Curved-surface large-view-field high-resolution catadioptric mixture mirror

By combining a refractive-reflective hybrid design with a series-connected Gregorian and reverse Cassegrain telescope structure and using aspheric and spherical lens groups, the problem of matching the two-photon microscope with the cerebral cortex under a large field of view was solved, enabling high-resolution monitoring of neuronal activity signals.

CN120802467APending Publication Date: 2025-10-17SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI +1
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Patent Information

Application Number
CN202511138348.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-08-14
Publication Date
2025-10-17

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Abstract

The invention provides a curved-surface large-view-field high-resolution catadioptric mixture mirror, which breaks through a conventional objective lens flat-field refraction type optical design scheme, and adopts a catadioptric mixed design scheme that a Grignard telescope structure and a reverse Cassegrain telescope structure are connected in series, and a lens group is embedded in a central position. The objective lens is a novel objective lens structure which is formed by mutual nesting of a lens group consisting of 14 spherical lenses, three of which are concave aspheric reflectors and one of which is convex aspheric reflectors) and the lens group consisting of 14 spherical lenses, and the effects of large view field area, high resolution, curved surface imaging (i.e., focal plane bending or view field bending) and excellent optical performance are realized, so that the optical invariant of a microscopic optical system is remarkably improved, and the objective lens is a novel objective lens structure which is formed by mutual nesting of the lenses. The problem that the two-photon flat-field mesoscopic objective lens is difficult to match with the curved surface of the cerebral cortex of the model animal in a wide-field range is solved, and the excitation efficiency of two photons can be effectively improved in a larger continuous range of the cerebral cortex of the model animal.
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