Radiotherapy end-to-end test die body and test system
By designing a cylindrical end-to-end radiotherapy test phantom, and utilizing a film-limiting structure and dose-forming layer, the problem of existing phantoms being unable to achieve three-dimensional dose measurement was solved, thus improving the accuracy and precision of three-dimensional dose measurement and making it suitable for the verification of various radiotherapy techniques.
Patent Information
- Application Number
- CN202511006039.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-21
- Publication Date
- 2025-10-24
AI Technical Summary
Existing end-to-end test phantoms make it difficult to achieve fast and convenient three-dimensional dose measurement, and the film is prone to warping and shifting during the curling process, resulting in inaccurate measurements.
A radiotherapy end-to-end testing phantom is designed, with a cylindrical phantom body and circumferentially extended film mounting positions. Through film limiting structures and dose building layers, the film is ensured to remain in contact during the rolling process to avoid displacement, thereby achieving three-dimensional dose measurement.
It achieves effective fixation of the three-dimensional rolled structure of the film, improves the accuracy and precision of three-dimensional dose measurement, increases the effective measurement area, and is suitable for dose distribution verification of various image-guided radiotherapy methods and complex radiotherapy techniques.
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Figure CN120831689A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to radiotherapy technology, in particular to a radiotherapy end-to-end test phantom and test system. BACKGROUND
[0002] End-to-end testing is a common quality assurance method in the field of radiotherapy. Modern radiotherapy usually consists of several relatively independent steps such as CT simulation positioning, target and organ at risk delineation, treatment plan design and verification, patient positioning and treatment plan implementation, etc. These steps are connected by a series of interdependent stages and actions. Therefore, end-to-end testing plays a key role in radiotherapy equipment, technology acceptance and quality assurance, and can ensure patient safety, treatment accuracy and technical reliability.
[0003] End-to-end test phantoms are one of the effective tools for implementing radiotherapy end-to-end testing, and can provide a physical experimental basis for simulating and reproducing the whole process of radiotherapy such as image acquisition, plan design and dose delivery. The phantom used for end-to-end testing is usually designed based on tissue equivalent materials and has different structures according to different quality control purposes. Most phantoms simulate the target and important organs at risk and embed dose detection devices (such as point dose or film) to reproduce and measure the whole process of clinical treatment. Through this end-to-end testing based on the phantom, not only can the deviation of a single link in the clinical process be found, but also the cumulative error in the whole process and multi-system cooperation can be exposed, thereby ensuring that the radiotherapy equipment and technology meet the stringent accuracy and error requirements in clinical application.
[0004] End-to-end test phantoms need to set up films or detectors for dose measurement. Existing end-to-end test phantoms are mostly point dose or two-dimensional dose measurement, and cannot quickly and conveniently realize three-dimensional dose measurement.
[0005] SUMMARY
[0006] The present application provides a radiotherapy end-to-end test phantom and test system to solve the problem that the end-to-end test phantom is difficult to realize quick and convenient three-dimensional dose measurement.
[0007] In a first aspect, the present application provides a radiotherapy end-to-end test phantom, comprising:
[0008] The phantom main body is of a cylindrical structure and is provided with a circumferentially extending film mounting position;
[0009] The film limiting structure is located on both sides of the film mounting position, one end of the film limiting structure is connected to the phantom main body, the other end of the film limiting structure extends towards the film mounting position, and an edge limiting groove is formed between the film limiting structure and the film mounting position, the edge limiting groove is used for inserting the edge of the film.
[0010] In some embodiments, the film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is spaced along the circumferential side of the phantom body, one end of each of the limiting frames is fixed to the phantom body, the other end of each of the limiting frames extends towards the film mounting position and forms the edge limiting groove with the film mounting position, and the circumferential adjacent limiting frames form a film mounting opening which communicates with the edge limiting groove.
[0011] In some embodiments, the radiotherapy end-to-end test phantom further comprises a dose building layer, the dose building layer comprises at least two film pressing covers, each of the film pressing covers is sequentially spliced and encloses the film mounting position, is used for pressing the film of the film mounting position along the circumferential side of the film, and adjacent two film pressing covers are detachably connected.
[0012] In some embodiments, the film pressing cover is made of tissue-equivalent material, and the thickness of the film pressing cover is between 5-15mm.
[0013] In some embodiments, the radiotherapy end-to-end test phantom further comprises a film positioning structure, the film positioning structure comprises a latitude scale line and a plurality of longitude scale lines, the latitude scale line is marked in the circumferential direction of the phantom body, and each of the longitude scale lines is marked in the axial direction of the phantom body and is uniformly spaced along the circumferential direction of the phantom body.
[0014] In some embodiments, the inner side of the phantom body forms a water containing cavity, the radiotherapy end-to-end test phantom further comprises a convenient operation end, the convenient operation end is fixed to the end of the phantom body and communicates with the water containing cavity, and the upper and lower sides of the convenient operation end are respectively provided with a water supply port and a drainage port which communicate with the inside of the convenient operation end.
[0015] In some embodiments, the radiotherapy end-to-end test phantom further comprises a dose building layer, the dose building layer encloses the film mounting position and is used for pressing the film of the film mounting position along the circumferential side of the film.
[0016] In some embodiments, the dose building layer comprises at least two film pressing covers, each of the film pressing covers is sequentially spliced and encloses the film mounting position, and adjacent two film pressing covers are detachably connected.
[0017] In some embodiments, the phantom body is a cylindrical structure, and the radiotherapy end-to-end test phantom further comprises an insert structure, the insert structure is arranged on the inner side of the phantom body.
[0018] In some embodiments, the radiotherapy end-to-end test phantom further comprises a plug-in structure, the plug-in structure comprising a detector plug-in and a target organ simulation plug-in, the detector plug-in and the target organ simulation plug-in being arranged inside the phantom body.
[0019] In some embodiments, the radiotherapy end-to-end test phantom further comprises a plug-in structure, the plug-in structure comprising a detector plug-in and a target organ simulation plug-in, the detector plug-in and the target organ simulation plug-in being arranged inside the phantom body.
[0020] In some embodiments, the plug-in board is provided with a plurality of insertion holes, the detector plug-in and the target organ simulation plug-in being inserted into any of the insertion holes, the detector plug-in and the target organ simulation plug-in being in sliding connection with the insertion slot and the insertion hole.
[0021] In some embodiments, the radiotherapy end-to-end test phantom further comprises a plug-in structure, the plug-in structure comprising a detector plug-in and a target organ simulation plug-in, the detector plug-in and the target organ simulation plug-in being arranged inside the phantom body.
[0022] The radiotherapy end-to-end test phantom provided by the present application comprises a phantom body, a film limiting structure, and a plug-in structure. The phantom body is in a cylindrical structure and is provided with a circumferentially extending film mounting position, which can be used to wind and mount a film. The film limiting structure is arranged on both sides of the film mounting position. The film limiting structure and the phantom body form an edge limiting slot through an end extending towards the film mounting position, which can effectively limit the film. Since the film is wound on the film mounting position and has a certain elasticity, the film can be kept in close contact with the film limiting structure under the elastic force of the film itself, effectively preventing the film from being raised. In addition, the film and the film limiting structure can effectively prevent the film from being deviated due to friction. Therefore, the radiotherapy end-to-end test phantom can ensure the accuracy of three-dimensional dose measurement and realize the measurement of three-dimensional dose. BRIEF DESCRIPTION OF DRAWINGS
[0023] The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present application and serve to explain the principles of the present application, together with the description.
[0024] Figure 1 is a structural schematic diagram of the radiotherapy end-to-end test phantom provided by the embodiments of the present application;
[0025] Figure 2 is a top view of the radiotherapy end-to-end test phantom provided by the embodiments of the present application;
[0026] Figure 3 is a sectional view along Figure 2 the line A-A in Fig. 1;
[0027] Figure 4 is a sectional view along Figure 3 the line A-A in Fig. 1;
[0028] Figure 5 is a structural schematic diagram of a radiotherapy end-to-end test phantom hidden dose build-up layer provided by an embodiment of the present application;
[0029] Figure 6 is a sectional view along Figure 5 the line A-A in Fig. 1;
[0030] Reference signs in the drawings:
[0031] 10 - phantom main body; 11 - film mounting position; 12 - square support plate; 13 - water containing cavity; 121 - pull hole;
[0032] 20 - film limiting structure; 21 - edge limiting groove; 22 - limiting frame; 221 - film mounting opening;
[0033] 30 - film positioning structure; 31 - latitude scale line; 32 - longitude scale line;
[0034] 40 - dose build-up layer; 41 - film pressing cover; 411 - lock catch;
[0035] 50 - convenient operation end; 51 - water supply port; 52 - water discharge port;
[0036] 60 - plug-in structure; 61 - plug-in board; 62 - plug-in slot; 611 - plug-in hole; 612 - water passing hole.
[0037] The specific embodiments of the present application have been shown in the above drawings, and will be described in more detail hereinafter. These drawings and written descriptions are not intended to limit the scope of the concept of the present application in any way, but to illustrate the concept of the present application to those skilled in the art by referring to specific embodiments. DETAILED DESCRIPTION
[0038] The exemplary embodiments will be described in detail herein with reference to the attached drawings. The same numbers are used in different drawings to represent the same or similar elements. The embodiments described in the following exemplary embodiments are not meant to represent all implementations consistent with the present application. Rather, they are merely examples of apparatus and methods consistent with some aspects of the present application as detailed in the appended claims.
[0039] The radiotherapy end-to-end test phantom provided by the embodiment of the present application is mainly used for quality assurance of radiotherapy, and in particular, in various image-guided adaptive radiotherapy, the overall performance of the radiotherapy system is evaluated by simulating the entire treatment process, including patient positioning, treatment planning, online adaptive plan adjustment, and accuracy of dosimetry. The end-to-end test phantom usually performs point dose measurement with a detector or two-dimensional dose measurement with a film. In the process of installing the film, the film is usually laid flat on the measurement plane, so that only two-dimensional dose measurement can be generally achieved. If three-dimensional dose measurement is to be achieved, the film needs to be curled to form a three-dimensional structure. However, the film area is large, and it is difficult to ensure that the film is accurately on the target measurement curved surface during the curling process, and local curling and deviation are prone to occur, thereby affecting the accuracy of dose measurement. In addition, in different application scenarios, the radiotherapy end-to-end test phantom generally needs to achieve functions such as dosimetry, imaging, and human body simulation. The existing phantom needs to be improved in terms of three-dimensional dose measurement, applicability of various image-guided radiotherapy modes, and simulation of target region organs and fraction changes.
[0040] To solve the technical problem that the end-to-end test phantom is difficult to achieve three-dimensional dose measurement with a film, the present application provides a radiotherapy end-to-end test phantom, which can provide good limiting for the film, thereby effectively fixing the three-dimensional curled structure of the film, achieving three-dimensional dose measurement and improving measurement accuracy.
[0041] The technical solutions of the present application and how the technical solutions of the present application solve the above technical problems will be described in detail in the specific embodiments below. The specific embodiments below can be combined with each other, and the same or similar concepts or processes can not be described in detail in some embodiments. The embodiments of the present application will be described below with reference to the drawings.
[0042] In order to better understand the present application, the following will be described in combination with Figures 1 to 6 The technical solutions of the present application will be described in detail:
[0043] The radiotherapy end-to-end test phantom provided by the embodiment of the present application includes a phantom main body 10 and a film limiting structure 20, as shown in Figure 5 The phantom main body 10 is a cylindrical structure, and the surface of the phantom main body 10 is provided with a circumferentially extending film mounting position 11. The film limiting structure 20 is located on both sides of the film mounting position 11, as shown in Figures 3-6 One end of the film limiting structure 20 is connected to the phantom main body, and the other end of the film limiting structure 20 extends towards the direction of the film mounting position 11 and forms an edge limiting groove 21 between the cylindrical film mounting position 11, and the edge limiting groove 21 is used for inserting and mounting the edge of the film.
[0044] Specifically, the radiotherapy end-to-end test phantom is provided by setting a phantom body 10 and a film limiting structure 20, the surface of the phantom body 10 is provided with a circumferentially extending film mounting position 11, the film mounting position 11 can be used for winding and mounting the film, the film limiting structure 20 is arranged on both sides of the film mounting position 11, and the film limiting structure 20 is limited by an edge limiting groove 21 formed by the film limiting structure 20 and the phantom body 10 and extending towards the film mounting position 11, so that the film can be effectively limited to facilitate imaging and dose measurement. Since the film is wound on the film mounting position 11 and the film itself has a certain elasticity, the film can be kept in close contact with the film limiting structure 20 under the elastic action of the film itself, the film is effectively prevented from being raised, the film is effectively prevented from being deviated due to friction between the film and the film limiting structure 20, and the film is not needed to be clamped by a clamping structure, thereby the film can be prevented from being damaged. Through the winding of the film, the phantom can complete the accurate measurement of three-dimensional dose distribution in a single test, thereby improving the measurement accuracy, and the effective area of the phantom can be effectively increased relative to the flat measurement.
[0045] In the embodiment, the film is a special irradiation color film for dose measurement, and generally has a certain flexibility and elasticity. The film can record the dose distribution and irradiation range of the rays and other key information. Through analysis of the dose distribution on the film, the dose irradiation of the imaging radiotherapy equipment can be verified. Therefore, the film is kept in close contact with the film limiting structure 20, thereby effectively improving the accuracy of dose measurement.
[0046] In the embodiment, the phantom body 10 is a main structure of the radiotherapy end-to-end test phantom and is made of a tissue-equivalent material, for example, solid water or polystyrene, which has physical and radiation characteristics similar to human tissue. In the embodiment, the phantom body 10 is polymethyl methacrylate (PMMA), which is a high polymer material with excellent transparency, mechanical properties and chemical stability, and has good chemical stability and biocompatibility.
[0047] It can be understood that the phantom body 10 can be a square cylinder, an elliptical cylinder or a circular cylinder structure.
[0048] In the embodiment, as shown in Figure 3 and 5 , the phantom body 10 is a hollow cylindrical structure, the length of the phantom body 10 is 420 mm, the outer diameter is 210 mm, and the inner diameter is 190 mm. The film mounting position 11 is arranged on the outer circumferential surface of the cylindrical phantom body 10. The cylindrical phantom body 10 has the advantages of simple structure, simulation of real human tissue, multifunctionality, applicability to various imaging angles, stable performance, convenience for positioning and calibration, and applicability to dynamic testing.
[0049] In the embodiment, in order to stabilize the phantom, aFigures 1-3 As shown in FIGS. 5 and 6, two square supporting plates 12 are arranged at two ends of the mold body 10, and the square supporting plates 12 are tightly combined with the mold body 10 and have a height of 380 mm, a width of 260 mm, and a thickness of 15 mm. The bottom of the square supporting plate 12 extends out of the mold body 10 to form a base, and the square supporting plate 12 can be stably placed on a platform to provide support for the mold. A lifting hole 121 is arranged at the upper end of the square supporting plate 12 to facilitate the transportation of the mold.
[0050] It can be understood that the mold body 10 and the square supporting plate 12 are not limited to the above-mentioned sizes. The size of the mold body 10 can be adaptively set according to actual testing, and the square supporting plate 12 only needs to have enough space to arrange the lifting hole 121 and the base.
[0051] In this embodiment, as shown in FIGS. 7 and 8, the film limiting structure 20 is a limiting ring 23 that is slidably connected to the mold body 10. Figures 1-3 As shown in FIGS. 9 and 10, the limiting ring 23 has an open edge limiting groove 21 on the inner side thereof. When the limiting ring 23 is slidably connected to the mold body 10, after the film is arranged in the film mounting position 11, the limiting ring 23 is slid toward the film to make the film enter the edge limiting groove 21 to limit the film. Figure 5 As shown in FIGS. 11 and 12, the film limiting structure 20 is a limiting frame 22 that is hingedly connected to the mold body 10. The limiting frame 22 has an open edge limiting groove 21 on the inner side thereof. The limiting frame 22 is hingedly connected to one side of the film mounting position 11. Before the film is arranged in the film mounting position 11, the limiting frame 22 is opened. After the film is arranged in the film mounting position 11, the limiting frame 22 is rotated toward the film to make the edge portion enter the edge limiting groove 21 to limit the film.
[0052] It can be understood that the film limiting structure 20 can be a limiting ring that is slidably connected or threadedly connected to the mold body 10. The inner side of the limiting ring is provided with an open edge limiting groove 21. When the limiting ring is slidably connected to the mold body 10, after the film is arranged in the film mounting position 11, the limiting ring is slid toward the film to make the film enter the edge limiting groove 21 to limit the film. When the limiting ring is threadedly connected to the mold body 10, after the film is arranged in the film mounting position 11, the limiting ring is rotated to make the limiting ring axially move toward the film to make the film enter the edge limiting groove 21 to limit the film. The film limiting structure 20 can also be a limiting frame 22 that is hingedly connected to the mold body 10. The inner side of the limiting frame 22 is provided with an open edge limiting groove 21. The limiting frame 22 is hingedly connected to one side of the film mounting position 11. Before the film is arranged in the film mounting position 11, the limiting frame 22 is opened. After the film is arranged in the film mounting position 11, the limiting frame 22 is rotated toward the film to make the edge portion enter the edge limiting groove 21 to limit the film.
[0053] In some embodiments, as shown in FIGS. 13 and 14, the film limiting structure 20 includes a plurality of limiting frames 22. Each limiting frame 22 is arranged on one side of the film mounting position 11 and is spaced apart along the circumferential side of the mold body 10. Figures 1-6 As shown in FIGS. 15 and 16, one end of each limiting frame 22 is fixed to the mold body 10, and the other end of each limiting frame 22 extends toward the film mounting position 11 to form an edge limiting groove 21 between the limiting frame 22 and the film mounting position 11. Figures 3-6 Figures 1-2 As shown in FIG. 5, the circumferentially adjacent limiting racks 22 form a film installation opening 221, and the film installation opening 221 is in communication with the edge limiting groove 21. Specifically, the limiting rack 22 is in a folded structure, and the inner side forms the edge limiting groove 21. The limiting racks 22 are arranged at intervals along the circumferential side of the phantom main body 10, and can provide limiting for the film in the circumferential direction. Since the film installation opening 221 is formed between the adjacent limiting racks 22, when the film is installed, only the end of the film needs to be inserted into the film installation opening 221, and then sequentially pass through the edge limiting groove 21 of each limiting rack 22, so that the film can be wound and installed on the film installation position 11. The film limiting is realized, and the installation of the film is facilitated.
[0054] It can be understood that the limiting rack 22 can be fixedly connected with the phantom main body 10, or connected in a sliding manner.
[0055] In this embodiment, as shown in FIG. 2, Figures 3-6 each limiting rack 22 is in a folded structure.
[0056] In this embodiment, the film installation opening 221 is arranged, so that the limiting rack 22 does not hinder the installation of the film. Therefore, the end of the limiting rack 22 is fixedly connected with the phantom main body 10.
[0057] In this embodiment, as shown in FIG. 5, Figure 5 the radiotherapy end-to-end test phantom further includes a film positioning structure 30. The film positioning structure 30 includes a latitude scale line 31 and a plurality of longitude scale lines 32. The latitude scale line 31 is marked on the circumferential direction of the phantom main body 10, and each longitude scale line 32 is marked on the axial direction of the phantom main body 10 and is uniformly spaced along the circumferential direction of the phantom main body 10. Specifically, the film positioning structure 30 can provide accurate positioning for the film in the three-dimensional space through the combination of the latitude scale line 31 and the plurality of longitude scale lines 32, so as to accurately obtain the spatial distribution information of the dose in the three-dimensional space. The film positioning structure 30 makes up for the deficiency of the traditional phantom which only supports point dose or surface dose measurement, and is especially suitable for verifying the dose distribution accuracy of various complex radiotherapy technologies such as intensity modulated radiotherapy. In combination with the measurement of the dose by the detector plug-in, the dose of various complex radiotherapy technologies can be accurately obtained.
[0058] In this embodiment, as shown in FIG. 5, Figure 5As shown, the film positioning structure 30 is engraved on the film mounting position 11, the latitude line 31 is a central circumferential line engraved on the central part of the film mounting position 11 in the circumferential direction, and the longitude line 32 is an axial line engraved on the film mounting position 11 in the axial direction. The longitude line 32 is uniformly spaced along the circumferential direction of the film mounting position 11, and the number thereof can be adaptively set according to actual needs. In the embodiment, there are 8 uniformly spaced longitude lines 32. The longitude line 32 takes the intersection with the latitude line 31 as the zero point, and marks the uniform scale in the direction of both ends of the film mounting position 11. The scale is set as 1 mm as a unit. The two sides of the latitude line 31 are positive scale and negative scale, respectively. The specific positive scale and negative scale can be determined according to actual application.
[0059] To further improve the measurement accuracy, in some embodiments, as shown in Figures 1-3 As shown, the radiotherapy end-to-end test phantom also includes a dose building layer 40 surrounding the film mounting position 11 for pressing the film of the film mounting position 11 along the circumferential side of the film. Specifically, the dose building layer 40 is located between the two groups of film limiting structures 20, and the dose building layer 40 is sleeved on the film of the film mounting position 11, thereby pressing the film in the circumferential direction, so that the two sides of the film can be tightly fitted with the film mounting position 11 and the dose building layer 40, respectively, thereby reducing the measurement error.
[0060] As can be understood, the dose building layer 40 can be fixed to the phantom main body 10 and extend to the plug-in interfaces at both ends, which are connected with the film mounting port 221. When the film is installed, the film can be inserted between the dose building layer 40 and the phantom main body 10 through the plug-in interface, and the end of the film is inserted into the edge limiting groove 21, thereby achieving the installation of the film. The dose building layer 40 can also be an arc-shaped fixed part and an arc-shaped flip part. The arc-shaped fixed part is fixed to the phantom main body 10, and the arc-shaped flip part is hinged to the arc-shaped fixed part. After the installation of the film in the film mounting position 11 is completed, only the arc-shaped flip part needs to be covered. The two arc-shaped structures of the dose building layer are not fixed to the phantom main body, and both are movable. In fact, it should be as described in the third paragraph below.
[0061] In some embodiments, as shown in Figures 1-3As shown, the dose building layer 40 comprises at least two film pressing covers 41, each film pressing cover 41 is sequentially spliced and encloses the film mounting position 11, and the adjacent two film pressing covers 41 are detachably connected. Specifically, by setting the dose building layer 40 as the detachable film pressing cover 41, after the film is mounted in the film mounting position 11, the film pressing covers 41 can be abutted and locked to form a cylindrical dose building layer 40 structure to limit the film. Through this setting, the dose building layer 40 can be detached relative to the phantom main body 10, on the one hand, it can facilitate the observation of the mounting state of the film, and on the other hand, it can facilitate the carrying of the phantom.
[0062] It can be understood that the film pressing cover 41 can be a plurality of blocks capable of splicing to form a cylindrical structure, and the adjacent film pressing covers 41 can be detachable through the cooperation of the embedding protrusions and the embedding grooves, or through the connection of the bolts.
[0063] In this embodiment, as shown in the figure, Figure 1 The number of film pressing covers 41 is two, and the two ends of the two film pressing covers 41 are abutted to form a cylindrical dose building layer 40, and the abutted part of the film pressing cover 41 is provided with a lock 411. After the film is mounted in the film mounting position 11, the two film pressing covers 41 are sleeved on the film and abutted with each other, and then they are buckled by the lock 411.
[0064] In some embodiments, the film pressing cover is made of tissue equivalent material, and the thickness of the film pressing cover is between 5-15mm. Specifically, the film measures the radiation dose by using the photosensitive property under the irradiation of the rays, and the film pressing cover can form a certain thickness on the film. The tissue equivalent material is similar in density to the human body, and by setting the thickness of the film pressing cover to be between 5-15mm, the photosensitive property of the film under the irradiation of the rays can be at the best value, which can ensure the measurement accuracy of the radiation dose.
[0065] In this embodiment, the tissue equivalent material for making the film pressing cover can be organic glass, high-density chlorovinyl, etc., and the thickness of the film pressing cover can be 5mm, 15mm, and any value between 5-15mm, for example, the thickness of the film pressing cover can also be 7mm, 10mm, etc.
[0066] In some embodiments, as shown in the figure, Figure 3 The inner side of the phantom main body 10 forms a water containing cavity 13, and the end-to-end test phantom for radiotherapy further comprises a convenient operation end 50, which is fixed to the end of the phantom main body 10 and communicates with the water containing cavity 13. The upper and lower sides of the convenient operation end 50 are respectively provided with a water inlet 51 and a water outlet 52.
[0067] Specifically, the phantom body 10 forms a water cavity 13 through the internal hollow structure, which contains water or magnetic resonance imaging liquid. When the water or magnetic resonance imaging liquid is supplied, it is conveniently supplied into the inside of the convenient operation end 50 through the water supply port 51, then enters the water cavity 13, and after the measurement is completed, the water or magnetic resonance imaging liquid can be discharged from the water outlet 52. The water or magnetic resonance imaging liquid can simulate human tissues, provide imaging conditions closer to the real human body, and at the same time provide good contrast in magnetic resonance imaging, ensuring the visibility and stability of the phantom in the magnetic resonance guided radiotherapy scene.
[0068] In this embodiment, as shown in Figure 1 and Figure 2 , the convenient operation end 50 is detachably fixed to the square support plate 12 provided with the supply plug plate 61 by a plurality of bolts, realizing the detachable connection of the convenient operation end 50 and the phantom body 10. When the phantom is transported, the convenient operation end 50 can be detached from the square support plate 12, facilitating the transportation of the phantom.
[0069] In this embodiment, as shown in Figures 1-3 , the radiotherapy end-to-end test phantom also includes a plug-in structure, which simulates different clinical scenarios and test conditions to provide a comprehensive solution for performance evaluation of radiation imaging equipment, ensuring that the equipment can provide accurate and reliable diagnostic information in actual application.
[0070] It can be understood that the plug-in structure can include one or more or a composite type of detector plug-in, target organ simulation plug-in, X-ray imaging quality control plug-in, magnetic resonance imaging quality control plug-in, etc. Whether the plug-in needs to be exactly the same as the shape of the human organ depends on the application purpose and specific needs. In the scene where high-precision simulation and real operation experience are required, the plug-in usually needs to simulate the shape and structure of the human organ as much as possible. However, in some specific applications or preliminary research, the plug-in may only need to simulate some key characteristics or functions of the organ, without the need to completely copy its appearance.
[0071] In some embodiments, as shown in Figures 1-3 , the plug-in structure includes a detector plug-in (not labeled in the figure) and a target organ simulation plug-in (not labeled in the figure), and the supply plug plate 61 is fixed to the end of the phantom body 10. The detector plug-in and the target organ simulation plug-in are both inserted into the supply plug plate 61 and located on the inside of the phantom body 10.
[0072] Specifically, the supply plug-in plate 61 is fixed at the end of the phantom main body 10, which can be used for detector plug-in and target organ simulation plug-in. The detector plug-in is used to measure the dose deposition of radiotherapy rays in the phantom, verify the dose accuracy of the treatment plan, and ensure that the actual dose is consistent with the planned dose. The target organ simulation plug-in is used to simulate lesions or specific areas in the human body. By combining the use of detector plug-in and target organ simulation plug-in, the dose distribution of specific areas can be measured. This combination can provide more comprehensive performance evaluation, ensuring the reliability and accuracy of radiotherapy equipment and technology in practical application.
[0073] In this embodiment, the target organ simulation plug-in includes a conventional plug-in that simulates the target organ, or a composite plug-in that internally sets the detector plug-in.
[0074] In some embodiments, as shown in Figures 1-3 , the radiotherapy end-to-end test phantom further includes a supply plug-in structure 60, which includes a supply plug-in plate 61 and a slot 62. The slot 62 is arranged at one end of the phantom main body for plug-in structure to be inserted and installed. The supply plug-in plate 61 is detachably connected to the other end of the phantom main body for the other end of the plug-in structure to be inserted and installed. Specifically, through the arrangement of the supply plug-in structure 60, when the plug-in structure is installed, one end of the plug-in structure is first inserted and installed in the slot 62, and the plug-in structure is pre-fixed. Then, the supply plug-in plate 61 is sleeved on the other end of the plug-in structure and installed on the phantom main body, thereby cooperating with the slot 62 to realize the stable fixation of the plug-in structure. Therefore, through the above arrangement of the plug-in structure, the installation of the plug-in structure is facilitated.
[0075] In this embodiment, as shown in Figure 3 , the square support plate 12 is provided with a fitting groove coaxial with the phantom main body 10. The supply plug-in plate 61 is installed in the fitting groove. The supply plug-in plate 61 is fitted in the fitting groove, which can realize the detachable connection of the supply plug-in plate 61 with the phantom main body 10, and provide positioning for the installation of the supply plug-in plate 61, thereby providing positioning for the detector plug-in and the region of interest simulation.
[0076] In some embodiments, as shown in Figure 1 , Figure 3 , and Figure 5As shown, the plug-in board 61 is provided with a plurality of plug holes 611, and the detector plug-in and the target organ simulation plug-in are respectively connected with the plug holes 611 and the plug slots 62 in a sliding mode. Specifically, by arranging a plurality of plug holes 611 on the plug-in board 61, the detector plug-in and the target organ simulation plug-in can be installed in any plug hole 611 and plug slot 62 according to actual needs, thereby supporting multi-angle and multi-position plug-in installation, so that the user can quickly replace different plug-ins according to actual needs, and achieve the simulation purpose of motion between fractions and different treatment scenarios. The universality of the phantom under different test conditions is significantly improved, and the test scene limitation caused by the fixed plug-in design is avoided. Moreover, since the detector plug-in and the target organ simulation plug-in are respectively connected with the plug holes 611 and the plug slots 62 in a sliding mode, the position of the detector plug-in and the target organ simulation plug-in can be adjusted by axial sliding, thereby improving the detection accuracy of the detector plug-in and the target organ simulation plug-in and the simulation accuracy of the target organ.
[0077] It can be understood that the plug holes 611 can be uniformly or non-uniformly arranged on the plug-in board 61, as long as they can meet the selective plug-in of the detector plug-in and the target organ simulation plug-in.
[0078] In this embodiment, as shown in Figure 3 , Figure 5 , the plug holes 611 and the plug slots 62 are arranged in a radial manner on the plug-in board 61.
[0079] It can be understood that, in order to avoid rotation of the detector plug-in and the target organ simulation plug-in, the plug holes 611 and the plug slots 62 can be arranged as plug holes of any shape other than a circular plug hole, such as an oval plug hole, a square plug hole, a special-shaped plug hole, etc.
[0080] In this embodiment, as shown in Figure 1 , Figure 3 and Figure 5 , the plug holes 611 and the plug slots 62 are hexagonal holes.
[0081] In this embodiment, as shown in Figure 5 , the edge of the plug-in board 61 is provided with a water passing hole 612, which is in communication with the water containing cavity 13 and the interior of the convenient operation end 50, so as to allow water or magnetic resonance imaging liquid to enter or exit the water containing cavity 13.
[0082] In this embodiment, the water inlet 51 of the convenient operation end 50 can not only supply water to the interior of the convenient operation end 50, but also serve as a control port for controlling the sliding of the detector plug-in and the target organ simulation plug-in, thereby providing convenience for adjustment of the detector plug-in and the target organ simulation plug-in.
[0083] In this embodiment, the inside of the convenient operation end 50 is also provided with a limiting groove 53, the limiting groove 53 is opposite to the insertion groove 62, and the end of the detector plug-in and the target area organ simulation plug-in can also be fixed to the limiting groove 53, so that the stability of the detector plug-in and the target area organ simulation plug-in is realized.
[0084] In this embodiment, the end-to-end test phantom does not use metal components in material use to ensure magnetic resonance compatibility.
[0085] The radiotherapy end-to-end test phantom provided by the embodiment of the application can complete accurate measurement of three-dimensional dose distribution in a single test, the film is curled and attached along the film mounting position 11 on the outer surface of the phantom main body 10, the dose building layer 40 ensures that the film is in close contact with the inner surface of the film mounting position 11 and the dose building layer 40, and measurement error is reduced, and the position recording function of the latitude scale line 31 and the longitude scale line 32 can be combined to accurately obtain spatial information of the dose distribution. The radiotherapy end-to-end test phantom makes up for the deficiency of the traditional phantom that only supports point dose or surface dose measurement, and is especially suitable for verifying the dose distribution accuracy of various complex radiotherapy technologies such as intensity modulated radiotherapy, and the cylindrical arrangement of the phantom can increase the effective test area of the phantom and support the use demand of complex treatment scenarios such as large-volume long target area or connected target area;
[0086] The water-containing cavity 13 formed in the inside of the phantom main body 10 can contain water or magnetic resonance imaging liquid, can better simulate the human body fluid environment, and ensures the visibility and stability of the phantom in the magnetic resonance guided radiotherapy scene;
[0087] The plug-in structure can simultaneously evaluate the dose output and imaging quality of the imaging equipment by combining the use of the detector plug-in and the target area organ simulation plug-in, can provide more comprehensive performance evaluation by cooperating with three-dimensional spatial measurement and evaluation, can ensure the reliability and accuracy of the equipment in actual application, can cooperate with the film to perform dose measurement, the detector plug-in and the target area organ simulation plug-in can be installed according to actual needs, and therefore support plug-in installation at multiple angles and multiple positions, so that the user can quickly replace different plug-ins according to actual needs, achieve the simulation purpose of inter-fraction motion and different treatment scenarios, improve the universality of the phantom under different test conditions, and reduce the test scene limitation caused by the fixed design.
[0088] In addition, the structure of the phantom is convenient to disassemble and assemble, thereby facilitating transportation and use, reducing use cost, and expanding the application range of the phantom.
[0089] In this embodiment, the two ends of the film are located on the film limiting structure 20 on the phantom main body 10 and are fixed by the dose building layer 40, and three-dimensional dose measurement is realized.
[0090] The inside of the phantom main body 10 is a hollow water-containing cavity 13, which can be filled with liquid, and can be used for multiple imaging modes such as X-ray and magnetic resonance, and is suitable for multiple image-guided radiotherapy modes.
[0091] The inside of the radiotherapy end-to-end test phantom is provided with a plug-in structure 60, and by adjusting the types and angle positions of different plugs, the point dose measurement function and the target organ treatment fraction change simulation function can be realized alone or in combination.
[0092] The embodiment of the present application also provides an end-to-end test system, which comprises a film and the radiotherapy end-to-end test phantom, the film is wound and installed at the film installation position 11 of the radiotherapy end-to-end test phantom, and the two ends of the film are located at the edge limiting grooves 21 of the radiotherapy end-to-end test phantom.
[0093] Specifically, the radiotherapy end-to-end test phantom can verify and analyze the errors of the tested system in the actual radiotherapy implementation process through full-process simulation of the actual radiotherapy scene, and ensure the accuracy of the system in the actual radiotherapy implementation.
[0094] In the embodiment, the two ends of the film are located at the film limiting structure 20 on the phantom main body 10 and are fixed by covering the dose buildup layer 40, so that three-dimensional dose measurement is realized.
[0095] The process of using the radiotherapy end-to-end test phantom to perform end-to-end test on the adaptive radiotherapy workflow can be performed according to the following steps:
[0096] Film dose calibration: using an ionization chamber and an electrometer, the measurement film is subjected to absolute dose calibration under a radiotherapy accelerator;
[0097] Installation of plug-in: the detector plug-in and the target organ simulation plug-in to be used are installed in the end-to-end test phantom;
[0098] CT simulation positioning: the assembled phantom is placed on a CT bed, a simulation film is inserted, the dose buildup layer is covered and fixed, water is poured into the phantom main body until there is no air bubble in the phantom main body, and CT simulation positioning is implemented;
[0099] Reference treatment plan design: reference treatment plan design and transmission are performed in a treatment planning system based on the CT simulation positioning image;
[0100] Simulation of treatment process: the phantom is transferred to a radiotherapy treatment bed and positioned, the simulation film is replaced with a measurement film, the position of the target organ simulation plug-in is fine-tuned to simulate the organ motion between fractions, and a complete adaptive radiotherapy treatment process is implemented;
[0101] Film analysis: The measurement film was taken out from the phantom, and the dose distribution on the film was quantitatively analyzed using a film scanner, combined with the point dose measurement results of the detector insert, and compared with the calculation results of the treatment planning system to analyze the errors in the whole adaptive radiotherapy process.
[0102] Other embodiments of the application will be apparent to those skilled in the art from consideration of the specification and practice of the application disclosed herein. It is intended that the specification and examples be considered as exemplary only, with the true scope and spirit of the application being indicated by the following claims.
[0103] It is to be understood that the application is not limited to the precise details of construction and the above-described and illustrated exact construction, and that various modifications and changes can be applied to the application without departing from the scope thereof or sacrificing any of its advantages. The scope of the application is accordingly indicated in the appended claims, rather than in the foregoing description.
Claims
1. A radiotherapy end-to-end test phantom, characterized in that, The radiation therapy end-to-end test phantom comprises a phantom body, a film limiting structure, and a film positioning structure. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body.
2. The radiotherapy end-to-end test phantom of claim 1, wherein, The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body.
3. The radiotherapy end-to-end test phantom of claim 1, wherein, The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body.
4. The radiotherapy end-to-end test phantom of claim 3, wherein, The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body.
5. The radiotherapy end-to-end test phantom of any of claims 1-4, wherein, The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body.
6. The radiotherapy end-to-end test phantom of any of claims 1-4, wherein, The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body.
7. The radiotherapy end-to-end test phantom of claim 6, wherein, The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body.
8. The radiotherapy end-to-end test phantom of claim 7, wherein, The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body.
9. The radiotherapy end-to-end test phantom of claim 8, wherein, The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body.
10. A radiotherapy end-to-end testing system, characterized by, The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames, each of which is located on both sides of the film mounting position and is arranged along the circumferential side of the phantom body. The film limiting structure comprises a plurality of limiting frames