Provocation system for inputting dry cold air to diagnose rhinitis and method of using the same

By using a miniaturized and intelligent dry and cold air excitation system, combined with filtration, dehumidification and heat exchange equipment, precise control of dry and cold air is achieved, solving the problems of large equipment footprint and difficult control, and improving the accuracy and economy of the experiment.

CN120860412BActive Publication Date: 2026-02-06TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
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Patent Information

Application Number
CN202511377867.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-09-25
Publication Date
2026-02-06
Estimated Expiration
2045-09-25

AI Technical Summary

Technical Problem

Existing dry and cold air nose provocation test equipment suffers from problems such as large equipment footprint, difficulty in high-precision single control of air source temperature and humidity, and lack of standardized equipment and standardized procedures.

Method used

A miniaturized and intelligent excitation system was designed, including a filtration device, a dehumidification device, and a heat exchange device. The airflow temperature and humidity are precisely controlled by a CNC device. A condenser and a desiccant are used for dehumidification and drying. A data acquisition device and a CNC module are integrated for real-time dynamic adjustment.

Benefits of technology

It achieves precise control of dry and cold air, improves the repeatability and accuracy of experimental data, reduces the space occupied by the equipment, and lowers the requirements for the air source, thus having good application prospects and economic value.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application relates to an excitation system for inputting dry cold air to diagnose rhinitis and a method for using the same, and relates to the technical field of rhinitis diagnosis equipment. The excitation system comprises a collecting part, a numerical control device, a filtering device, a dehumidifying device, a heat exchange device with a heat exchange medium and an input device which are sequentially connected in the air flow direction. The collecting part is arranged on the air flow path. The numerical control device comprises a dehumidifying control module and a temperature control module. The dehumidifying control module calculates the air flow humidity RN accepted by the dehumidifying device based on the air flow humidity RC, and regulates the power of the dehumidifying device based on the air flow humidity RN. The temperature control module calculates the air flow temperature TN accepted by the heat exchange device based on the air flow temperature TC and the power of the dehumidifying device, and regulates the temperature of the heat exchange medium based on the air flow temperature TN. The input device comprises an input pipeline connected with the output end of the heat exchange device and a breathing mask connected with the input pipeline. The application has the effects of miniaturization and intelligentization.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of dry cold air input equipment, in particular to a provocation system for inputting dry cold air to diagnose rhinitis and a method of using the same. BACKGROUND

[0002] Nasal mucosa hyperresponsiveness is an important feature of airway diseases such as allergic rhinitis and non-allergic rhinitis. Dry cold air provocation test is widely recognized as the "gold standard" for evaluating nasal cavity hyperresponsiveness. However, dry cold air nasal provocation test is still in its infancy, lacking standardized equipment and standardized procedures.

[0003] Related document KR101281025B1 discloses a low-temperature and low-humidity air production device, which cools the oxygen (air) sprayed from a supply source in a cooler, separates and automatically discharges the condensed water from the oxygen (air), realizes the separation of water and air, and thus converts the oxygen (air) into low-temperature and low-humidity oxygen (air) for supply to a patient, which is used as a test tool for the purpose of diagnosing the patient. Related document CN207976784U discloses a low-temperature dry air preparation system, which provides the system with air of predetermined temperature and humidity through an air bottle, and the air enters a low-temperature cold trap after being decompressed for drying and refrigeration, and finally forms dry cold air for output to a patient. The system has the problems of large equipment floor space and difficulty in high-precision single control of dry cold air.

[0004] Therefore, there is an urgent need to provide a miniaturized and intelligent provocation system that can reduce the floor space while performing high-precision single control of the temperature and humidity of the air source, and improve the accuracy and practicality of the CDA test. SUMMARY

[0005] The present application provides a miniaturized and intelligent provocation system for inputting dry cold air to diagnose rhinitis and a method of using the same, which addresses the deficiencies of the existing cold air provocation test equipment.

[0006] In a first aspect, the provocation system for inputting dry cold air to diagnose rhinitis provided by the present application adopts the following technical solution:

[0007] A provocation system for inputting dry cold air to diagnose rhinitis, comprising:

[0008] A filter device, a dehumidification device and a heat exchange device are sequentially connected in the airflow flow direction;

[0009] A collection piece is arranged on the airflow flow path, which is used to obtain the temperature T C and the humidity R C of the airflow;

[0010] The numerical control device comprises:

[0011] a dehumidification control module connected with the collecting unit and the dehumidification device, configured to calculate the air humidity R C of the air flow based on the air humidity R N of the air flow, and regulate the working parameter of the dehumidification device based on the air humidity R N of the air flow.

[0012] a temperature control module connected with the collecting unit, the dehumidification control module and the heat exchange device, configured to calculate the air temperature T C of the air flow based on the air temperature T N of the dehumidification device, and regulate the working parameter of the heat exchange device based on the air temperature T N of the air flow.

[0013] an input device including an input conduit connected with the output end of the heat exchange device, and a breathing mask connected with the input conduit, the breathing mask configured to input dry cold air to the human body.

[0014] Optionally, the dehumidification device includes a condensing unit, and the dehumidification control module is connected with the condensing unit, configured to calculate the air humidity R C of the air flow based on the air humidity R N of the condensing unit, and regulate the working parameter of the condensing unit based on the air humidity R N of the air flow.

[0015] Optionally, the evaporator of the condensing unit is provided with a drainage device, and the drainage device includes:

[0016] a water collecting tray provided in a funnel shape and having a large-diameter end and a small-diameter end, the large-diameter end of the water collecting tray being in communication with the bottom of the evaporator;

[0017] a drain pipe in communication with the small-diameter end of the water collecting tray.

[0018] Optionally, the dehumidification device further includes a dehumidification unit detachably arranged between the heat exchange device and the condensing unit, and the dehumidification unit includes a tube body and a desiccant filled in the tube body.

[0019] Optionally, the tube bodies are closely arranged in a sheet shape along a vortex shape, and the dehumidification unit further includes a partition arranged in the tube body, the partition separating the tube body to form a first chamber and a second chamber arranged in sequence along the flow direction of the air flow.

[0020] The desiccant includes silica gel desiccant and molecular sieve desiccant, the silica gel desiccant is arranged in the first chamber, and the molecular sieve desiccant is arranged in the second chamber.

[0021] Optionally, the dehumidification device further comprises:

[0022] a first suction member arranged between the input device and the heat exchange device;

[0023] a second suction member arranged between the condensing member and the filtering device;

[0024] a constant-pressure transfer tank arranged between the heat exchange device and the condensing member, for storing or outputting air;

[0025] the dehumidification control module is connected with the second suction member, for adjusting the working parameter of the second suction member based on the air humidity R C calculating the air humidity R N of the condensing member, and adjusting the working parameter of the second suction member based on the air humidity R N .

[0026] adjusting the working parameter of the second suction member and the condensing member based on the air humidity R N .

[0027] Optionally, the collecting member comprises a temperature sensor and a humidity sensor, the temperature sensor is arranged between the heat exchange device and the dehumidification device, and the humidity sensor is arranged between the filtering device and the dehumidification device.

[0028] Optionally, the heat exchange device comprises:

[0029] a tank body in which a heat exchange medium is sealed and stored;

[0030] a temperature control member arranged in the tank body and connected with the temperature control module, for adjusting the temperature of the heat exchange medium;

[0031] a heat exchange pipeline arranged in the tank body in a spiral or vortex shape, an input end of the heat exchange pipeline being connected to the dehumidification device, and an output end of the heat exchange pipeline being connected to the input device.

[0032] Optionally, the heat exchange medium comprises any one of anhydrous ethanol solution, propylene glycol solution, calcium chloride solution or polyethylene glycol solution.

[0033] In a second aspect, the application provides a use method of the provoking system, which uses the provoking system for inputting dry and cold air to diagnose rhinitis, and comprises the following steps:

[0034] collecting the air temperature T C and the air humidity R C on the air flow path;

[0035] calculating the air humidity R C of the dehumidification device, and adjusting the working parameter of the second suction member based on the air humidity R N of the dehumidification device.and based on the air flow humidity R N adjusting the working parameters of the dehumidification device;

[0036] based on the air flow temperature T C , the power of the dehumidification device, calculating the air flow temperature T N , and based on the air flow temperature T N adjusting the working parameters of the heat exchange device.

[0037] In summary, the present application includes at least one of the following beneficial technical effects:

[0038] 1. In the present application, air is processed in multiple stages. After entering the system, the air is processed in the order of filtration, dehumidification, and temperature adjustment. During the processing, the temperature and humidity of the air are individually adjusted by the numerical control device to ensure that the temperature and humidity of the output air are accurately controllable, improve the repeatability of experimental data, and the system has good application prospects and can be used as a unified standard instrument, solving the problem that the temperature and humidity of the traditional cooler or low-temperature cold trap cannot be individually adjusted.

[0039] At the same time, the excitation system individually adjusts the temperature and humidity of the air through the numerical control device, which can adapt to a wide range of temperature and humidity air sources, has lower requirements for the temperature and humidity of the air source, and compared with the traditional system, reduces the setting of the air bottle, making the land occupation of the excitation system smaller.

[0040] 2. The condensing member of the present application is further combined with the dehumidification member. The dehumidification member uses a desiccant to dry the air after the condensing member, ensuring the drying effect while effectively saving energy.

[0041] 3. The dehumidification member in the present application uses a desiccant to dry the air. During the drainage process of the system, if part of the air enters the dehumidification member through the drainage device, it can also be filtered and dried to reduce the possibility of impurities in the final output of dry cold air. BRIEF DESCRIPTION OF DRAWINGS

[0042] Figure 1 is a schematic diagram of the overall structure of the excitation system in Embodiment 1 of the present application.

[0043] Figure 2 is another schematic diagram of the overall structure of the excitation system in Embodiment 1 of the present application.

[0044] Figure 3 is a schematic diagram of the overall structure of the excitation system in Embodiment 2 of the present application.

[0045] Figure 4 is a data example diagram of the excitation system of the present application when it is running.

[0046] Figure 5 is another data example diagram of the excitation system runtime of the present application.

[0047] In the figure, 1, filtering device; 2, dehumidifying device; 21, condensing component; 211, evaporator; 212, condenser; 213, compressor; 22, dehumidifying component; 23, first suction component; 24, second suction component; 25, third suction component; 3, heat exchange device; 4, collecting component; 5, numerical control device; 6, drainage device; 61, water collecting tray; 62, drain pipe; 7, input device; 71, input conduit; 72, breathing mask. DETAILED DESCRIPTION

[0048] The following will be combined with the accompanying Figures 1-5 The technical solutions of the present application are clearly and completely described. The following examples are exemplary and are used to explain the present application, but cannot be interpreted as a limitation of the present application. In the following description, the same reference signs are used to represent the same or equivalent elements, and repeated descriptions are omitted.

[0049] In the description of the present application, it should be understood that the terms "upper", "lower", "inner", "outer", "left", "right", etc. indicate the orientation or positional relationship shown in the drawings, or the orientation or positional relationship commonly used when the product of the present application is used, or the orientation or positional relationship commonly understood by those skilled in the art, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the indicated device or element must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation of the present application.

[0050] In addition, the terms "mounting", "connecting", "connecting" should be broadly understood, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0051] It should be further understood that the term "and / or" used in the present application means any combination of one or more of the listed items and all possible combinations.

[0052] Example 1:

[0053] An excitation system for inputting dry cold air to diagnose rhinitis, with reference to Figure 1The system includes a filter device 1, a dehumidifier 2, a heat exchanger 3, and an input device 7, which are sequentially connected along the airflow direction. The airflow is specifically set as air. After entering the excitation system, the air undergoes filtration, dehumidification, and temperature regulation in sequence. The resulting dry and cold air is finally input to the subject at a specified flow rate through the input device 7.

[0054] Reference Figure 1 The filter device 1 is installed at the input end of the dehumidifier 2, so that the air is filtered before entering the dehumidifier 2. While ensuring the cleanliness of the air entering the dehumidifier system, it also effectively isolates the pollutants in the air to prevent them from blocking the airflow path.

[0055] Specifically, the filtration device 1 includes a primary filtration layer and a secondary filtration layer arranged sequentially along the airflow direction, with the filtration performance of the secondary filtration layer being higher than that of the primary filtration layer.

[0056] The primary filter layer performs preliminary filtration of the air to remove large particles such as dust, pollen, hair, and lint; the secondary filter layer further refines the filtration of the air to remove PM2.5, pathogenic microorganisms, mold spores, dust mite debris, etc., ensuring that the air entering the dehumidifier 2 has a high degree of cleanliness.

[0057] In one specific embodiment, the primary filtration layer is set as a G4-grade pre-filter (using non-woven fabric, glass fiber, etc. as filter media), and the secondary filtration layer is set as an H13-grade HEPA filter (using polytetrafluoroethylene filter membrane, etc., as filter media). The G4-grade pre-filter and the H13-grade HEPA filter are connected. In other embodiments, other suitable combinations can also be used to ensure that the output dry and cold air is clean.

[0058] Reference Figure 1 The dehumidification device 2 includes a condenser 21 and a second suction device 24. The condenser 21 is disposed between the heat exchange device 3 and the filter device 1, and the second suction device 24 is disposed between the condenser 21 and the heat exchange device 3.

[0059] The second suction component 24 draws air from the external environment into the excitation system, and the condenser 21 dehumidifies the air entering the excitation system. Through the synergistic effect of the condenser 21 and the second suction component 24, the air in the external environment is finally processed to form dry and cold air that meets the requirements of flow rate and humidity.

[0060] It should be noted that the second suction component 24 mainly provides power for air to enter the system, and its specific location can be designed according to the internal spatial structure of the system. For example, the second suction component 24 can also be set between the condenser 21 and the filter device 1, or it can be set at the input end of the filter device 1.

[0061] Further, the condensing component 21 comprises an evaporator 211, a condenser 212 and a compressor 213 forming a closed loop, and a refrigerant is circulated in the condensing component 21. The refrigerant is converted into a high-temperature and high-pressure state in the compressor 213, and then is cooled in the condenser 212, and then is lowered in pressure to form a low-temperature and low-pressure state, and then absorbs heat of the air in the evaporator 211, so that the moisture in the air is removed in the form of liquid water or small ice crystals, thereby achieving dehumidification of the air.

[0062] It should be noted that the pipeline corresponding to the condenser and the evaporator has an expansion valve, and the refrigerant is lowered in pressure when passing through the expansion valve after being cooled in the condenser 212, and then enters the evaporator in a low-temperature and low-pressure state.

[0063] The evaporator 211 is divided into a first flow channel for the refrigerant and a second flow channel for the air. In this embodiment, the flow directions of the air and the refrigerant are opposite (i.e., counter-flow), and compared with the air and the refrigerant flowing in the same direction or parallel-flow, the temperature gradient of the refrigerant and the air can be more evenly distributed along the length direction of the evaporator 211 in the heat exchange process, thereby improving the efficiency of the refrigerant absorbing heat of the air.

[0064] Further, referring to Figure 1 , the evaporator 211 of the condenser 212 is provided with a drainage device 6, which is connected to the second flow channel and collects the liquid water or small ice crystals separated from the air when the air is dehumidified by the condensing component 21.

[0065] In a specific embodiment, the drainage device 6 comprises a water collecting tray 61 and a drain pipe 62. The water collecting tray 61 is provided in a funnel shape, and has a large-diameter end and a small-diameter end. The second flow channel is connected to the large-diameter end of the water collecting tray 61, and the drain pipe 62 is connected to the small-diameter end of the water collecting tray 61. The drain pipe 62 is provided with a valve for controlling the opening and closing of the drain pipe 62.

[0066] The water collecting tray 61 stores the liquid water and small ice crystals, and the valve on the drain pipe 62 is opened periodically to timely drain the liquid water or small ice crystals from the system, so as to reduce the accumulation of too much moisture in the second flow channel, thereby preventing the dehumidification device 2 from being blocked, and inhibiting the dehumidification and cooling effects of the dehumidification device 2.

[0067] On this basis, in another specific embodiment, a pressure sensor can be arranged in the water collecting tray 61. When the pressure value of the liquid water and small ice crystals detected by the pressure sensor exceeds a preset calibration value, the valve is automatically opened, thereby achieving the purpose of automatic water removal.

[0068] Referring to Figure 1The heat exchange device 3 includes a box, a temperature control device, and a heat exchange pipeline. The heat exchange medium is sealed and stored in the box. The temperature control device and the heat exchange pipeline are arranged in the box. The input end of the heat exchange pipeline is connected to the suction member. The output end of the heat exchange pipeline is connected to the input device 7. The heat exchange pipeline is arranged in the box in a spiral shape. The heat exchange pipeline has a large contact area with the heat exchange medium and optimizes the flow path of the air in the heat exchange pipeline, so as to improve the heat exchange effect.

[0069] When the humidity of the air after the dehumidification treatment of the condensing member 21 meets the requirements but the temperature does not meet the requirements, the air is further subjected to temperature adjustment treatment after passing through the heat exchange device 3. The temperature of the heat exchange medium is adjusted by the temperature control device. The heat exchange medium with the adjusted temperature exchanges heat with the air, so that the temperature of the air meets the requirements.

[0070] The temperature of the heat exchange medium is specifically set according to actual conditions. In a specific embodiment, the temperature of the heat exchange medium is set to 0-15°C.

[0071] The heat exchange medium is stored in the box in a liquid state. During operation, the output power of the temperature control device is controlled according to the temperature of the air output to the heat exchange device 3, so that the temperature of the heat exchange medium changes in the range of 0-15°C, so as to perform temperature increasing or decreasing treatment on the air.

[0072] Further, the heat exchange medium can be specifically set according to actual conditions. In a specific embodiment, the heat exchange medium can be set as anhydrous ethanol solution. The anhydrous ethanol solution has good heat conduction capacity and can remain in a liquid state at low temperature to continuously absorb or transfer heat.

[0073] Meanwhile, in another specific embodiment, considering that anhydrous ethanol has strong volatility and flammability, the heat exchange medium can also be set as any one of propylene glycol solution or polyethylene glycol solution, which have higher stability and safety than anhydrous ethanol.

[0074] It should be noted that the heat exchange efficiency of different heat exchange media is different. When the heat exchange medium is replaced, the temperature range of the heat exchange medium is adjusted correspondingly.

[0075] Referring to Figure 1 The input device 7 includes an input pipeline 71 and a breathing mask 72 connected to the input pipeline 71. The breathing mask 72 is used to input dry cold air to the human body. In the embodiment, considering that the dry cold air needs to be finally output to the breathing mask 72 through the input pipeline 71, in a specific embodiment, a temperature locking protective layer (for example, polyurethane foam plastic, aerogel, etc.) can be wrapped on the input pipeline 71 to reduce the possibility that the temperature of the air slightly rises when the air flows in the input pipeline 71.

[0076] In addition, in a specific embodiment, the breathing mask 72 is made of silica gel, and a one-way valve is arranged on the breathing mask 72 to prevent exhaled gas of the subject from entering the excitation system through the breathing mask 72 to cause air flow reflux, thereby ensuring that the output dry cold air can stably act on the user.

[0077] In an example, the breathing mask 72 has a filter module inside.

[0078] It should be noted that, compared with the filter device 1, the filter device 1 undertakes the main air filtering work to ensure the cleanliness of the air and reduce the air carrying dirt to block the air flow path. For the filter module, it is more used as a protective means. Specifically, if the pipeline corresponding to the air flow path is damaged, causing unfiltered air to enter the system, the filter module filters it to protect the subject.

[0079] In a specific embodiment, the filter module is a small HEPA filter, which undertakes the secondary filtering work and filters the particulate matter and bacteria that may still exist in the air after being processed by the filter device 1.

[0080] In another specific embodiment, the filter module can also be similar to the filter device 1 and be provided with a two-layer filter structure including a non-woven fabric and a small HEPA filter arranged in sequence to enhance the filtering effect.

[0081] Referring to Figure 1 , the excitation system further includes a collection part 4 and a numerical control device 5. When the system is working, the collection part 4 collects the air flow temperature T C and the air flow humidity R C and feeds back to the numerical control device 5. The numerical control device 5 dynamically controls the state of the dehumidification device 2 and the heat exchange device 3 in real time according to the feedback air flow temperature T C and the air flow humidity R C to match the air source with different temperatures and humidities (the temperature and humidity of air are obviously different in different regions and different seasons) so that the air is processed by the dehumidification device 2 and the heat exchange device 3 in sequence to form dry cold air with required dryness and humidity.

[0082] It should be noted that the excitation system is operated indoors, and the temperature fluctuation is small with the change of seasons. And with the change of seasons, the excitation conditions of the patient also change adaptively. Based on this, the temperature and humidity parameters of the dry cold air can be considered comprehensively according to the season, altitude and other conditions.

[0083] In an example, the present application takes 15℃ and 15%RH as the baseline. When the humidity of the dry cold air is <15%RH and the temperature is 0-15℃, it means that the parameter requirement is met.

[0084] The collection part 4 comprises a temperature sensor and a humidity sensor, which are connected to the numerical control device 5 to obtain the temperature and humidity of the air. The position of the collection part 4 can be set according to actual conditions.

[0085] In a specific embodiment, the temperature sensor and the humidity sensor are highly integrated.

[0086] On this basis, referring to Figure 1 , the collection part 4 can be arranged at the output end of the heat exchange device 3 to obtain the air flow temperature T C and the air flow humidity R C , which can be used as reference data for the numerical control device 5 to control the dehumidification device 2 and the heat exchange device 3, and can also be directly output as the temperature and humidity parameters of the dry cold air. In this case, the temperature loss of the air during the process of transferring from the input conduit 71 to the breathing mask 72 can also be further considered, and a temperature correction function can be designed to make the output data more accurate.

[0087] Alternatively, the collection part 4 can also be arranged at the output end of the filtering device 1 to obtain the air flow temperature T C and the air flow humidity R C , which can be used as reference data for the numerical control device 5 to control the dehumidification device 2 and the heat exchange device 3, and can also be directly output as the temperature and humidity parameters of the air source.

[0088] In addition, the collection part 4 can also be provided with two groups, one group of collection parts 4 is arranged at the output end of the heat exchange device 3, and the other group of collection parts 4 is arranged at the output end of the filtering device 1, which can actually record the temperature and humidity parameters of the air flow entering and outputting from the system, and there is no need to calculate the air flow humidity R N and the air flow temperature T N . The temperature and humidity of the air flow output by the collection part 4 can be directly used to control the dehumidification device 2 and the heat exchange device 3.

[0089] In another specific embodiment, the temperature sensor and the humidity sensor are separately arranged. The temperature sensor is arranged between the heat exchange device 3 and the dehumidification device 2, and the humidity sensor is arranged between the filtering device 1 and the dehumidification device 2 to be close to the corresponding device to be detected, so as to more accurately and directly detect the humidity and temperature.

[0090] Correspondingly, on this basis, the numerical control device 5 can also comprise an alarm module. When the humidity and temperature of the air output by the dehumidification device 2 are abnormal, the alarm module sends an abnormal signal to ensure that the system can stably and accurately operate.

[0091] In addition, in other specific embodiments, the acquisition device 4 further comprises a flow sensor connected with the numerical control device 5 to obtain the flow rate of the air, the flow sensor is used to detect the real-time flow rate when the dry cold air is output by the excitation system, and timely adjustment is made when the real-time flow rate deviates from the specified flow rate.

[0092] Correspondingly, the numerical control device 5 comprises a display module and a storage module, the display module is connected with the acquisition device 4 to visually display the temperature, humidity and flow of the air and the like, and the storage module stores the above data to facilitate data tracking and analysis.

[0093] Further, the numerical control device 5 further comprises a dehumidification control module, the dehumidification control module is connected with the acquisition device 4 and the dehumidification device 2, and the dehumidification control module adjusts the working parameters of the dehumidification device 2 based on the air flow humidity R C The dehumidification control module calculates the air flow humidity R N of the dehumidification device 2 based on the air flow humidity R N , and adjusts the working parameters of the dehumidification device 2.

[0094] The dehumidification control module dynamically adjusts the dehumidification device 2 in real time, so that the humidity of the air treated by the dehumidification device 2 is less than 15% RH.

[0095] In a specific embodiment, the dehumidification control module calculates the air flow humidity R N of the dehumidification device 2 based on the air flow humidity R N , and adjusts the working parameters of the condensing component 21 to make the humidity of the output air meet the humidity requirement.

[0096] Specifically, a large amount of experimental data is used to fit the relationship function between the air flow humidity R N and the working parameters of the condensing component 21, and when the working parameters of the condensing component 21 are adjusted, the corresponding working parameters of the condensing component 21 in the relationship function are selected based on the air flow humidity R N .

[0097] On this basis, the air flow humidity R B can be further set as a reference value based on the requirement that the humidity of the dry cold air is less than 15% RH, and the air flow humidity R B is within the temperature range. By comparing the air flow humidity R B with the humidity of the dry cold air output from the excitation system after the working parameters of the condensing component 21 are adjusted, the working parameters of the condensing component 21 are further adjusted to reduce the fluctuation of the humidity of the output dry cold air.

[0098] For example, the acquisition device 4 is arranged at the output end of the heat exchange device 3, at this time, the temperature and humidity parameters output by the acquisition device 4 can be directly used as the temperature and humidity parameters of the dry cold air, and the specific process of the excitation system working in this case is as follows:

[0099] First, air is introduced for a period of time, during which the dehumidification control module adjusts the power of the condenser 21 according to the acquired air humidity R N The corresponding working parameters of the condenser 21 in the relationship function are selected, and the dehumidification control module continuously adjusts the power of the condenser 21 until the output air humidity reaches the air humidity R B The main adjustment is completed.

[0100] After the main adjustment is completed, the air humidity R C is compared with the size of R B to make real-time dynamic adjustment. For example, when the air humidity R C is less than R B , the dehumidification control module reduces the power of the dehumidification device 22, thereby weakening the dehumidification effect; when the air humidity R C is greater than R B , the dehumidification control module increases the power of the dehumidification device 22, thereby strengthening the dehumidification effect; the specific value of the adjusted power is determined according to the difference between R C and R B .

[0101] The value of the air humidity R B is within the humidity range, and in a specific embodiment, a lower value can be taken as the air humidity R B , for example: R B = 6% RH, 8% RH or 10% RH. By setting a lower air humidity R B as a reference value to control the humidity of the final output dry cold air, the situation that the dry cold air does not meet the humidity requirement after the humidity fluctuates when the value is selected to be larger (for example: R B = 14% RH or 15% RH) is reduced.

[0102] In addition, it should be noted that when the acquisition device 4 is arranged at the input end of the dehumidification device 2, the air humidity R C tends to be consistent with the air humidity R N , the humidity value of the final output air can be calculated and deduced according to the running state of the dehumidification device 2, and the size thereof is compared with R B to make real-time dynamic adjustment; or, a set of acquisition devices 4 is added at the output end of the heat exchange device 3 to obtain the humidity value of the final output air.

[0103] In a specific embodiment, referring to Figure 2 , the dehumidification device 2 further comprises a first suction device 23 arranged between the input device 7 and the heat exchange device 3, and a constant-pressure transfer tank arranged between the heat exchange device 3 and the condenser 21, which outputs or stores gas when the power of the first suction device 23 and the second suction device 24 is inconsistent.

[0104] Considering that dry cold air needs to be output to the outside of the system at a specified flow rate, at this time the first suction member 23 is operated at a constant power to ensure that the air meets the specified flow rate, and the operating state of the second suction member 24 is regulated to adjust the dehumidification capacity. Correspondingly, the dehumidification control module is connected with the second suction member 24, and the dehumidification control module regulates the operating state of the second suction member 24 based on the air flow humidity R C The dehumidification control module calculates the air flow humidity R N of the dehumidification device 2, and regulates the operating parameter of the second suction member 24 based on the air flow humidity R N .

[0105] The above structure cooperates with the dehumidification control module to realize the adjustment of humidity. Among them, the way of controlling the second suction member 24 is opposite to the way of controlling the condensing member 21. Specifically, the power of the condensing member 21 is increased to strengthen the dehumidification effect, and the power is reduced to weaken the dehumidification effect; and the power of the second suction member 24 is increased to reduce the flow time of the air flow in the condensing member 21 to weaken the dehumidification effect, and the power is reduced to prolong the flow time of the air flow in the condensing member 21 to strengthen the dehumidification effect.

[0106] It should be noted that the principle of main adjustment and real-time dynamic adjustment of the embodiment is consistent with the above-mentioned embodiment, that is, a large number of experimental data are used to fit the relationship function between the air flow humidity R N and the operating parameter of the second suction member 24, when the operating parameter of the second suction member 24 is adjusted, the corresponding operating parameter of the second suction member 24 in the relationship function is selected based on the air flow humidity R N .

[0107] In another specific embodiment, the dehumidification control module calculates the air flow humidity R C of the dehumidification device 2, and regulates the operating parameter of the second suction member 24 based on the air flow humidity R N . N

[0108] Specifically, a large number of experiments are used to fit the composite relationship function between the air flow humidity R N and the operating parameters of the condensing member 21 and the second suction member 24, and when the operating parameters of the condensing member 21 and the second suction member 24 are adjusted, the corresponding operating parameters of the condensing member 21 and the second suction member 24 in the relationship function are selected based on the air flow humidity R N .

[0109] ​In one specific embodiment, the control primarily focuses on adjusting the power of the condenser 21. When the workload of the condenser 21 is about to become excessive, the operating parameters of the second suction component 24 are further adjusted. In another specific embodiment, the power of the condenser 21 and the second suction component 24 are adjusted simultaneously during control. Specifically, both the condenser 21 and the second suction component 24 output α to β% of their maximum power, and the percentage of power output by both is kept consistent.

[0110] By simultaneously controlling the operating parameters of the condenser 21 and the second suction component 24, the dehumidification effect of the dehumidification device 2 is enhanced, further reducing the humidity requirements of the air source. At the same time, under the same temperature and humidity conditions, compared to controlling only the condenser 21 or only the second suction component 24, this method can rationally distribute the working load of the condenser 21 and the second suction component 24, reducing the possibility of excessive long-term working load on the condenser 21.

[0111] Furthermore, the CNC equipment 5 also includes a temperature control module, which is connected to the data acquisition unit 4, the dehumidification control module, and the heat exchange equipment 3. The temperature control module is based on the airflow temperature T. C Power calculation of dehumidification equipment 2; airflow temperature T received by heat exchanger 3. N And based on the airflow temperature T N Adjust the operating parameters of heat exchanger 3.

[0112] The heat exchanger 3 is dynamically regulated in real time by the temperature control module so that the temperature of the air processed by the dehumidifier 2 is within 0 to 15°C.

[0113] In this embodiment, the temperature control module adjusts the operating parameters of the heat exchange device 3 by regulating the temperature of the heat exchange medium. The way the temperature control module regulates the heat exchange device 3 is similar to the way the dehumidification control module regulates the dehumidification device 2.

[0114] Specifically, a large amount of experimental data was used to fit the airflow temperature T. N The relationship function between the heat exchange medium temperature and the operating parameters of the heat exchange medium is based on the airflow temperature T. N Select the temperature of the heat exchange medium corresponding to the relational function.

[0115] Based on this, the airflow temperature T can be preset according to the requirement of dry and cold air temperature of 0-15℃. B As a reference value, airflow temperature T B Within the temperature range, by comparing the airflow temperature R B The temperature of the heat exchange medium is further adjusted to correspond with the temperature of the dry, cold air output from the excitation system after the temperature of the heat exchange medium has been adjusted, so as to reduce the fluctuation of the temperature of the output dry, cold air.

[0116] For example, the temperature and humidity parameters output by the collection member 4 at the output end of the heat exchange device 3 can be directly output as the temperature and humidity parameters of the dry cold air, and the specific process of the excitation system in this case is as follows:

[0117] First, air is introduced for a period of time, and during this period, the dehumidification control module continuously adjusts the power of the condenser 21 until the humidity of the output air reaches the air flow humidity R B The temperature control module further adjusts the temperature of the heat exchange medium after considering the power of the condenser 21 until the air temperature reaches the air flow temperature T B The requirements are met, and the main adjustment is completed. At this time, the breathing mask 72 is worn on the subject, and the dry cold air excitation system continuously inputs dry cold air to the subject;

[0118] During the input, the temperature of the heat exchange medium is dynamically adjusted in real time according to the size of the air flow temperature T C Compared with T B For example, when the air flow temperature T C <T B , the temperature control module increases the temperature of the heat exchange medium under the reference power of the dehumidification device 2; when the air flow temperature T C >T B , the temperature control module decreases the temperature of the heat exchange medium, and the specific value of the temperature of the heat exchange medium is determined according to the difference between T C and T B .

[0119] Wherein, the air flow temperature T B is within the temperature range, in a specific embodiment, a lower value can be taken as the air flow temperature T B , for example: T B =6℃, 8℃ or 10℃. By setting a lower air flow temperature T B as a reference value to control the temperature of the finally output dry cold air, to reduce the case that the dry cold air does not meet the temperature requirements after the temperature fluctuation when the value is selected to be larger (for example: T B =14℃ or 15℃).

[0120] In summary, the air entering the system in this application is filtered, dehumidified, and temperature-adjusted in sequence, and finally outputs dry cold air that can be applied to excitation tests. The system has strong temperature and humidity control ability, which reduces the requirements for air sources, can directly use external air as the air source, reduces the setting of air bottles compared to traditional systems, makes the system smaller, and has lower cost of preparing dry cold air, which has good economic value.

[0121] The system as a whole is a box structure, the above-mentioned filtering device 1, dehumidifying device 2, heat exchanging device 3, input device 7, collecting part 4, numerical control device 5 are integrated into the box, the overall size is 90cm:60cm:50cm, the box structure makes the system easy to move, and the small floor area of the box structure makes it can be further hidden under the table board. It should be noted that the specific size of the box is not limited to 90cm:60cm:50cm, the length, width and height can be further changed by ±5% of the above-mentioned size, for example, it can also be set to 88cm:59cm:48cm.

[0122] Embodiment 2:

[0123] A provocation system for inputting dry cold air to diagnose rhinitis, referring to Figure 3 which is the same as embodiment 1, except that the dehumidifying device 2 further includes a dehumidifying part 22 detachably arranged at the input end of the heat exchanging device 3, and the dehumidifying part 22 includes a pipe body and a desiccant filled in the pipe body.

[0124] Along the length direction of the pipe body, the pipe body can be any shape such as straight line type, arc shape, etc. In order to reduce the occupied volume of the air drying device, in a specific embodiment, the pipe body is closely arranged in a sheet shape along a vortex path, which reduces the space required when installing the dehumidifying part 22, optimizes the airflow path, reduces the resistance of the gas when passing through the desiccant, and makes the gas flow output more stable, and guarantees the dehumidifying effect of the dehumidifying part 22.

[0125] Further, referring to Figure 3 , the dehumidifying part 22 further includes a partition, which is arranged in the pipe body to partition the pipe body, forming a first chamber and a second chamber arranged in sequence along the airflow direction; correspondingly, the desiccant includes silica gel desiccant and molecular sieve desiccant, the silica gel desiccant is arranged in the first chamber, and the molecular sieve desiccant is arranged in the second chamber.

[0126] The silica gel desiccant has higher dehumidifying capacity than the molecular sieve desiccant in a high humidity environment. By combining the two kinds of desiccants, the dehumidifying part 22 can continuously output stable dehumidifying capacity within a specified time to perform secondary dehumidification on the air, further reducing the working load of the suction part and the condensing part 21.

[0127] At the same time, after the dehumidifying part 22 is added to the dry cold system, when part of the air enters the system through the drainage device 6, the silica gel desiccant and the molecular sieve desiccant can also filter it, so as to guarantee that the air has high cleanliness.

[0128] In addition, when the air enters the dehumidification device 2 for dehumidification, the temperature will drop simultaneously. For some air sources with high humidity but low temperature (such as in winter), the temperature will drop further after dehumidification, resulting in a large workload for the heat exchange device 3. At this time, the silica gel desiccant and molecular sieve desiccant will release heat after absorbing moisture, which will cause the air temperature to rise slightly and further reduce the workload of the heat exchange device 3.

[0129] Example 3:

[0130] A method of using a provocation system for diagnosing rhinitis by introducing dry, cold air includes the following steps:

[0131] Collect the airflow temperature T along the airflow path C airflow humidity R C ;

[0132] Based on airflow humidity R C Calculate the humidity R of the airflow received by dehumidifier 2 N And based on airflow humidity R N Adjust the operating parameters of dehumidifier 2;

[0133] Based on airflow temperature T C Power calculation of dehumidification equipment 2; airflow temperature T received by heat exchanger 3. N And based on the airflow temperature T N Adjust the operating parameters of heat exchanger 3.

[0134] As the airflow passes sequentially through dehumidification device 2 and heat exchange device 3, the CNC device 5 uses the collected airflow temperature T as a basis for its calculations. C airflow humidity R C It can precisely control the temperature and humidity of the air.

[0135] In one specific embodiment, a humidity threshold 'a' and a temperature threshold 'b' are set for the air. Based on the humidity threshold 'a', the air humidity is divided into three ranges: (0, 1 / 3a), (1 / 3a, 2 / 3a), and (2 / 3a, a). Similarly, the air humidity is divided into three ranges: (0, 1 / 3b), (1 / 3b, 2 / 3b), and (2 / 3b, b). (1 / 3a, 2 / 3a) is used as the calibrated humidity range, and (1 / 3b, 2 / 3b) is used as the calibrated temperature range.

[0136] The humidity threshold 'a' and temperature threshold 'b' are determined based on the actual local environment. For example, humidity threshold 'a' can be 40%RH, 60%RH, or 80%RH, and temperature threshold 'b' can be 30℃, 35℃, or 40℃.

[0137] When the humidity of the air source is within the calibrated humidity range, if the temperature is within the calibrated temperature range, the dehumidification device 2 and the heat exchange device 3 output normally; if the temperature is below the calibrated temperature range, the dehumidification device 2 outputs normally and the working parameters of the heat exchange device 3 are reduced; if the temperature exceeds the calibrated temperature range, the dehumidification device 2 outputs normally and the working parameters of the heat exchange device 3 are increased.

[0138] When the humidity of the air source exceeds the calibrated humidity range, if the temperature is below or within the calibrated temperature range, the working parameters of the dehumidification device 2 are increased and the working parameters of the heat exchange device 3 are reduced; if the temperature exceeds the calibrated temperature range, the working parameters of the dehumidification device 2 and the heat exchange device 3 are both increased.

[0139] When the humidity of the air source is below the calibrated humidity range, if the temperature exceeds or is within the calibrated temperature range, the working parameters of the dehumidification device 2 are reduced and the working parameters of the heat exchange device 3 are increased; if the temperature is below the calibrated temperature range, the working parameters of the dehumidification device 2 and the heat exchange device 3 are both reduced.

[0140] It should be noted that, in a specific embodiment, the dehumidification device 2 operates at m-n% rated power when it outputs normally, and the inner heat exchange medium of the heat exchange device 3 operates at j-k℃ when it outputs normally. In other embodiments, adaptive adjustments can be made according to the specific parameters of the dehumidification device 2 and the heat exchange device 3.

[0141] The following examples illustrate the operation of the excitation system shown in Figure 3 when performing primary regulation, with the actual temperature and humidity of the air being 80% RH and 40℃.

[0142] It should be noted that the excitation system needs to run for a period of time to form dry cold air with temperature and humidity parameters meeting the requirements when performing primary regulation. In actual use, the excitation system does not act on the patient immediately after starting to run. The following examples take the time when the excitation system starts to act on the patient as the starting time and record the changes in temperature and humidity parameters of the dry cold air within 30 minutes.

[0143] Example 1:

[0144] An air source has a temperature of 28℃ and a humidity of 60% RH before entering the excitation system. After primary regulation, the temperature and humidity parameters of the air output by the excitation system are as shown in Figure 4 .

[0145] Example 2:

[0146] An air source has a temperature of 28℃ and a humidity of 50% RH before entering the excitation system. After primary regulation, the temperature and humidity parameters of the air output by the excitation system are as shown in Figure 5 .

[0147] The embodiments of the present application are preferred embodiments of the present application, and are not intended to limit the protection scope of the present application, wherein the same parts are denoted by the same reference numerals. Therefore, any equivalent changes made according to the structure, shape and principle of the present application should be covered within the protection scope of the present application.

Claims

1. A provocation system for diagnosing rhinitis by introducing dry, cold air, characterized in that, include: The filter (1), dehumidifier (2) and heat exchanger (3) are connected sequentially along the airflow direction. The data acquisition unit (4) is located on the airflow path and is used to acquire the airflow temperature TC and airflow humidity R. C ; CNC equipment (5), including: A dehumidification control module, which is connected to the data acquisition unit (4) and the dehumidification device (2); A temperature control module is connected to the data acquisition unit (4), the dehumidification control module, and the heat exchange device (3); The input device (7) includes an input conduit (71) connected to the output end of the heat exchange device (3) and a breathing mask (72) connected to the input conduit (71). The breathing mask (72) is used to input dry and cold air into the human body and has a filter module inside. The dehumidification device (2) includes a condenser (21), and the dehumidification control module is connected to the condenser (21) for controlling the humidity based on the airflow R. C Calculate the humidity R of the airflow received by the condenser (21). N And based on the airflow humidity R N Adjust the operating parameters of the condenser (21); The dehumidification device (2) further includes a dehumidification component (22) detachably disposed between the heat exchange device (3) and the condenser (21), the dehumidification component (22) including a tube body and a desiccant filled in the tube body; The tube body is arranged in a tightly packed sheet shape along a vortex direction. The dehumidifying component (22) also includes a partition disposed in the tube body. The partition separates the tube body to form a first chamber and a second chamber arranged sequentially along the airflow direction. The desiccant includes silica gel desiccant and molecular sieve desiccant, with the silica gel desiccant disposed in the first chamber and the molecular sieve desiccant disposed in the second chamber; The dehumidification device (2) also includes: The first suction element (23) is located between the input device (7) and the heat exchange device (3); The second suction element (24) is located between the condenser (21) and the filter (1); A constant pressure transfer tank is located between the heat exchange equipment (3) and the condenser (21) for storing or outputting air; The dehumidification control module is connected to the second suction component (24) and is used to control the humidity based on the airflow R. C Calculate the humidity R of the airflow received by the condenser (21). N And based on the airflow humidity R N Adjust the operating parameters of the second suction component (24); or Based on the airflow humidity R N Adjust the operating parameters of the second suction component (24) and the condenser component (21).

2. The excitation system according to claim 1, characterized in that, The bottom of the evaporator (211) of the condenser (21) is provided with a drainage device (6), the drainage device (6) comprising: The water collection tray (61) is configured as a funnel and has a large diameter end and a small diameter end. The large diameter end of the water collection tray (61) is connected to the bottom of the evaporator (211). The drain pipe (62) is connected to the small diameter end of the water collection tray (61).

3. The excitation system according to claim 1, characterized in that, The acquisition device (4) includes a temperature sensor and a humidity sensor. The temperature sensor is located between the heat exchange device (3) and the dehumidification device (2), and the humidity sensor is located between the filtration device (1) and the dehumidification device (2).

4. The excitation system according to claim 1, characterized in that, The heat exchange device (3) includes: The enclosure contains a sealed heat exchange medium. A temperature control device is installed inside the chamber and connected to the temperature control module to adjust the temperature of the heat exchange medium. The heat exchange pipe is arranged in a spiral or vortex shape inside the box. The input end of the heat exchange pipe is connected to the dehumidification device (2), and the output end of the heat exchange pipe is connected to the input device (7).

5. The excitation system according to claim 4, characterized in that, The heat exchange medium includes any one of anhydrous ethanol solution, propylene glycol solution, or polyethylene glycol solution.

6. A method of using an excitation system, characterized in that, The excitation system described in any one of claims 1-5 includes the following steps: Collect the airflow temperature T along the airflow path C airflow humidity R C ; Based on the airflow humidity R C Calculate the humidity R of the airflow received by the dehumidification device (2). N And based on the airflow humidity R N Adjust the operating parameters of the dehumidification device (2); Based on the airflow temperature T C The power calculation of the dehumidification device (2) and the airflow temperature T received by the heat exchange device (3) N And based on the airflow temperature T N Adjust the operating parameters of the heat exchanger (3).

Citation Information

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