Traditional Chinese medicine composition for preventing cold and treating early symptoms of cold and preparation method of traditional Chinese medicine composition

Abstract

The invention relates to a traditional Chinese medicine composition for preventing cold and treating early symptoms of cold and a preparation method, and belongs to the technical field of traditional Chinese medicine preparations. The composition is prepared from radix aconiti lateralis praeparata slices, radix astragali, cassia twigs and other traditional Chinese medicines according to a specific weight part ratio, and has the dual functions of prevention and treatment through the synergistic effects of strengthening yang, tonifying qi, strengthening superficies, regulating ying and wei, reducing phlegm and stopping coughing. During preparation, the raw materials are mixed and then subjected to superfine grinding to prepare powder, or the raw materials are extracted and concentrated to prepare granules, the granules are subpackaged into independent tea bag preparations, and one bag of the tea bag preparations is brewed for drinking every day. The composition takes yang warming, superficies consolidating and immunity enhancing as the core, and is combined with lung ventilating and phlegm reducing components to relieve symptoms such as cough and throat itching in a targeted manner; a standardized preparation process is combined with a medicinal tea form, so that the problem that a traditional decoction is inconvenient to decoct is solved; the traditional Chinese medicine composition is suitable for long-term prevention of old people and people with low immunity, and has fast effect and high safety on early-stage cold patients. The traditional Chinese medicine theory and the modern preparation technology are combined, and the traditional Chinese medicine composition has the advantages of being rigorous in formula, convenient to take and controllable in quality.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition for preventing cold and treating early symptoms of cold and a preparation method thereof. BACKGROUND

[0002] Traditional Chinese medicine in the field of cold prevention and treatment mostly uses single-effect prescription, or focuses on strengthening healthy qi and consolidating the exterior, or focuses on eliminating pathogenic factors and relieving the exterior, which is difficult to meet the dual needs of prevention and early treatment. Although existing powders and granules have certain applications, they generally have the following limitations:

[0003] 1. The prescription lacks synergistic design, and the physical adaptability for the elderly and immunocompromised population is insufficient;

[0004] 2. The preparation process is rough, such as traditional decoction method leading to loss of effective components, and the particle size control of powders affects the dissolution rate;

[0005] 3. The taking method is not convenient, lacks quantitative packaging design, and is difficult to meet the compliance needs of susceptible population for long-term prevention. In addition, it is found in clinical practice that the conventional preparations have limited effect on relieving symptoms such as sticky sputum, itching cough, etc. in the early stage of cold.

[0006] In view of the above problems, it is urgent to develop a traditional Chinese medicine compound preparation which integrates the theory of strengthening healthy qi and eliminating pathogenic factors, has a standardized preparation process and is convenient to take. SUMMARY

[0007] The present application provides a traditional Chinese medicine composition for preventing cold and treating early symptoms of cold and a preparation method thereof to solve the problems of the prior art.

[0008] To solve the above technical problems, the present application is realized by the following technical scheme: in the first aspect, a traditional Chinese medicine composition for preventing cold and treating early symptoms of cold is composed of the following raw materials in weight ratio:

[0009] Fuzi 3 parts, Zixiao flower 2 parts, Luoyang 2 parts, Guizhi 2 parts, Fuling 2 parts, Huangqi 3 parts, Chenpi 2 parts, Baizhu 2 parts, Banxia 2 parts, Jingjie 2 parts, Fangfeng 2 parts, Xingren 2 parts, Jujiang 2 parts, Kuanfeng 2 parts, Zixian 2 parts, Shegan 2 parts, Gancao 1 part, Mudu 1 part, Sangbaipi 2 parts, Hupu 2 parts, Hongcha 1 part.

[0010] The application forms a compound preparation with the synergistic effects of supporting yang, tonifying qi, and consolidating the exterior, regulating the Ying and Wei, and resolving phlegm and relieving cough by scientifically matching the traditional Chinese medicine formula. The prescription takes the pill for warming yang and dispelling cold as the monarch, and is matched with Astragalus, Atractylodes for tonifying qi and consolidating the exterior, Cinnamon Twig and Windproof for regulating the Ying and Wei, Violet and Winter Flower for resolving phlegm and relieving cough, Purple Tip Flower and Lock Yang for warming and tonifying kidney yang, Magnolia Bark and Tangerine Peel for regulating qi and resolving phlegm, Platycodon and Apricot Kernel for descending lung qi, Belamcanda and Butterfly Pea for benefiting the throat and relieving cough, White Mulberry Bark for clearing lung heat, Poria for invigorating the spleen and draining dampness, Pinellia for drying dampness and resolving phlegm, Schizonepeta for relieving the exterior and dispelling pathogenic factors, and Licorice for regulating all the medicines, and is supplemented with Red Tea for leading the medicine upward and improving the taste. The components are matched in a specific ratio to have synergistic effects, which can not only enhance the body defense function of the elderly and people with low immunity, effectively preventing the occurrence of cold, but also play the therapeutic role of promoting lung and resolving phlegm, benefiting the throat and relieving cough for the symptoms of cough, throat itching, and sticky sputum difficult to expectorate, etc. in the early stage of cold. The preparation is in the form of powder or granules, and is made into an independent packaged tea preparation through a standardized crushing or extraction process, which not only retains the active ingredients of traditional Chinese medicine decoction pieces, but also has the convenience of being ready to drink. The daily one-bag design ensures the safety and compliance of drug use. The scheme combines the traditional Chinese medicine theory of supporting the body and eliminating evil with modern preparation technology to form a traditional Chinese medicine health care product with prevention and treatment integration, and has the characteristics of rigorous formula, synergistic effect, and easy popularization.

[0011] In a specific embodiment of the first aspect, the weight ratio of each raw material component allows a preparation error of ±10%.

[0012] The second aspect is a preparation method of a traditional Chinese medicine composition for preventing cold and treating symptoms in the early stage of cold, which comprises the following steps:

[0013] After mixing each raw material component according to the ratio, the powder is prepared by crushing, or the granules are prepared by extraction, and is packaged into a tea bag type.

[0014] In a specific embodiment of the first aspect, the tea bag preparation is independently packaged, and the daily dose is one bag.

[0015] The third aspect is the application of a traditional Chinese medicine composition for preventing cold and treating symptoms in the early stage of cold, which is used for:

[0016] Preventing the occurrence of cold in the elderly and people with low immunity

[0017] Treating patients in the early stage of cold with symptoms of cough, sticky sputum difficult to expectorate, and throat itching.

[0018] The fourth aspect is a traditional Chinese medicine tea preparation for preventing cold and treating symptoms in the early stage of cold, which contains a traditional Chinese medicine composition for preventing cold and treating symptoms in the early stage of cold, and contains:

[0019] Fuzi 3-3.3g, Zixiao Hua 2-2.2g, Duzhong 2-2.2g, Gudzhi 2-2.2g, Fuling 2-2.2g, Huangqi 3-3.3g, Chenpi 2-2.2g, Baizhu 2-2.2g, Banxia 2-2.2g, Jingjie 2-2.2g, Fangfeng 2-2.2g, Xingren 2-2.2g, Juemingeng 2-2.2g, Kuanfenghua 2-2.2g, Ziyuan 2-2.2g, Shegan 2-2.2g, Gancao 1-1.1g, Muduobe 1-1.1g, Sangbaipi 2-2.2g, Hupu 2-2.2g, Hongcha 1-1.1g.

[0020] The beneficial effects of the present application are:

[0021] 1. Through scientific compatibility of Fuzi, Huangqi, Gudzhi and other traditional Chinese medicines, a synergistic system with triple functions of "supporting Yang, benefiting Qi and consolidating the exterior, regulating Ying and Wei, resolving phlegm and relieving cough" is formed: to enhance the immunity of the body by warming Yang and consolidating the exterior, to reduce the susceptibility to cold of the elderly and weak people, to quickly relieve the symptoms of early cold by the targeted combination of promoting the lung and benefiting the throat, resolving phlegm and relieving cough, to convert the traditional prescription into a tea agent form which can be brewed and drunk immediately by combining the standardized preparation process of dispersible granules, to solve the problems of complicated decoction and difficult dosage control of traditional decoction while ensuring the stable release of active ingredients. Finally, a traditional Chinese medicine health care product with rigorous prescription, convenient taking and suitable for long-term promotion is formed, which has the advantages of both TCM theory support and modern preparation technology. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the present application will be clearly and completely described below in combination with the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0023] A traditional Chinese medicine composition for preventing cold and treating early symptoms of cold and a preparation method thereof.

[0024] Embodiment 1: Preparation of the traditional Chinese medicine composition

[0025] (1) Raw material ratio: the following traditional Chinese medicine decoction pieces are accurately weighed according to weight parts:

[0026] Fuzi 3 parts, Zixiao Hua 2 parts, Duzhong 2 parts, Gudzhi 2 parts, Fuling 2 parts, Huangqi 3 parts, Chenpi 2 parts, Baizhu 2 parts, Banxia 2 parts, Jingjie 2 parts, Fangfeng 2 parts, Xingren 2 parts, Juemingeng 2 parts, Kuanfenghua 2 parts, Ziyuan 2 parts, Shegan 2 parts, Gancao 1 part, Muduobe 1 part, Sangbaipi 2 parts, Hupu 2 parts, Hongcha 1 part.

[0027] (2) Preparation process:

[0028] Powder preparation: After mixing the above decoction pieces, dry and sterilize, use a super micro grinder to crush to a particle size of ≤150 μm, sieve and pack into filter paper tea bags, each bag containing a total of 40 g of crude drugs (error ± 5%).

[0029] Granule preparation: Mix the decoction pieces and decoct twice (first time with 10 times the amount of water, decoct for 1.5 hours; second time with 8 times the amount of water, decoct for 1 hour), combine the decoction and concentrate to a relative density of 1.20-1.25 (60°C), add dextrin as an excipient (drug solution to dextrin weight ratio 3:1), granulate and dry, then pack as granules, each bag containing 40 g of crude drugs equivalent to the original medicinal materials.

[0030] Example 2: Method of using tea infusion preparations

[0031] (1) Indications:

[0032] Preventive use: Suitable for people over 60 years old or those with weak constitution and prone to repeated colds, take continuously for 3-5 days per week.

[0033] Therapeutic use: For those with symptoms of initial colds such as itching in the throat, coughing, and thick mucus that is not easily coughed out, take 1 dose daily continuously until symptoms are alleviated.

[0034] (2) Method of taking:

[0035] Take one tea bag, add 200-300 ml of boiling water, cover and steep for 10-15 minutes, then drink, and can be repeated until the medicinal flavor is weak.

[0036] Example 3: Allowed preparation error of component ratio

[0037] In actual production, the weight ratio of each raw material component is allowed to have a preparation error of ±10%. For example:

[0038] The amount of attached pieces is in the range of 2.7-3.3 parts, purple tip flowers are 1.8-2.2 parts, black tea is 0.9-1.1 parts, and the rest of the components are adjusted in the same proportion.

[0039] The total amount of crude drugs is controlled within the range of 38-42 g per bag.

[0040] Example 4: Verification of synergistic effect of technical solutions

[0041] Through clinical observation (selecting 100 susceptible people):

[0042] Preventive group (50 cases): Take according to the method of Example 2, continuously for 3 months, the incidence of colds is reduced by 62%.

[0043] Treatment group (50 cases): take within 24 hours after the initial symptoms of cold, cough relief time is shortened by an average of 48 hours, sputum discharge efficiency increased by 55%.

[0044] While embodiments of the application have been shown and described, it is to be understood that the embodiments described are merely divergences of the principles and spirit of the application and that numerous modifications, changes, substitutions, and alterations can be made thereto without departing from the spirit and scope of the application as defined by the appended claims and their equivalents.

Claims

1. A traditional Chinese medicine composition for preventing cold and treating early symptoms of cold, characterized in that: The following raw materials are mixed in the following proportions by weight: ​ Fupi 3 parts, Zixiao Hua 2 parts, Suanzaoren 2 parts, Guizhi 2 parts, Fuling 2 parts, Huangqi 3 parts, Chenpi 2 parts, Baizhu 2 parts, Banxia 2 parts, Jingjie 2 parts, Fangfeng 2 parts, Xingren 2 parts, Jiegeng 2 parts, Kuan Donghua 2 parts, Ziyuan 2 parts, Shegan 2 parts, Gancao 1 part, Mudanpi 1 part, Sangbaipi 2 parts, Hupu 2 parts, Hongcha 1 part.

2. The Chinese medicine composition for preventing cold and treating initial symptoms of cold according to claim 1, characterized in that: The proportions of the raw materials are allowed to have a preparation error of ±10%.

3. A method for preparing a traditional Chinese medicine composition for preventing cold and treating early symptoms of cold, characterized in that: The following steps are included: After mixing the raw materials according to the proportions, the mixture is crushed to make a powder or extracted to make granules, which are packaged as a tea bag type.

4. The method for preparing the Chinese medicine composition for preventing cold and treating early symptoms of cold according to claim 3, characterized in that: The tea bag type is packaged individually, and each bag contains a single daily dose.

5. The use of a Chinese medicine composition for preventing cold and treating early symptoms of cold, characterized in that, For: Preventing colds in the elderly and people with low immunity Treating patients in the early stages of colds with symptoms such as cough, sticky sputum, and throat itching.

6. A traditional Chinese medicine tea preparation for preventing colds and treating early symptoms of colds, characterized in that: A Chinese medicine composition for preventing colds and treating early symptoms of colds, as claimed in claim 1, contains the following daily dose: Fupi 3-3.3g, Zixiao Hua 2-2.2g, Suanzaoren 2-2.2g, Guizhi 2-2.2g, Fuling 2-2.2g, Huangqi 3-3.3g, Chenpi 2-2.2g, Baizhu 2-2.2g, Banxia 2-2.2g, Jingjie 2-2.2g, Fangfeng 2-2.2g, Xingren 2-2.2g, Jiegeng 2-2.2g, Kuan Donghua 2-2.2g, Ziyuan 2-2.2g, Shegan 2-2.2g, Gancao 1-1.1g, Mudanpi 1-1.1g, Sangbaipi 2-2.2g, Hupu 2-2.2g, Hongcha 1-1.1g.