Super-resolution imaging method, display method and ultrasonic imaging device

Abstract

The invention discloses a super-resolution imaging method, a display method and an ultrasonic imaging device, and the method comprises the steps: controlling an ultrasonic probe to emit a first ultrasonic wave to a target tissue, and generating and displaying a first tissue image; selecting a super-resolution imaging area on the first tissue image; controlling the ultrasonic probe to emit a second ultrasonic wave to the target tissue injected with the contrast agent, processing the second ultrasonic echo data based on the first imaging parameter to obtain first data, and processing the first data based on a first contrast agent microbubble identification threshold to generate a first super-resolution contrast image; displaying the first super-resolution contrast image; and in response to a received user instruction for amplifying the first super-resolution contrast image, processing the second ultrasonic echo data based on a second imaging parameter to obtain second data, and processing the second data based on a second contrast agent microbubble identification threshold to generate a second super-resolution contrast image.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of ultrasonic imaging, and more particularly to an ultrahigh-resolution imaging method, a display method and an ultrasonic imaging device. BACKGROUND

[0002] Ultrasonic medical imaging is a method of using ultrasonic waves as a detection means to display the image of the internal organs of the human body by receiving the scattering, reflection or projection of the sound waves on the surface of the human body. If a medium (micro-bubble) with a sound impedance that is completely different from that of the blood is added to the blood, the scattering in the blood is enhanced, which is the basic principle of acoustic contrast. Ultrasonic contrast imaging is based on the nonlinear oscillation of contrast agent micro-bubbles under the driving of acoustic emission, and at a lower acoustic pressure, the contrast micro-bubbles are not easy to break, the duration is long, and the tissue around the micro-vessels almost only produces a linear fundamental wave component, so that the linear information of the tissue can be suppressed by the transmission of the positive and negative pulses, and the nonlinear signal component from the micro-bubbles is enhanced for imaging to obtain an ultrasonic image with high signal-to-noise ratio. It is just by using this principle that ultrasonic contrast agent, i.e. a solution containing micro-bubbles, is injected into the vein, and the contrast agent perfuses into the organs and tissues along with the blood flow, so that the organs and tissues are developed or developed to enhance, thereby providing an important basis for clinical diagnosis.

[0003] When a doctor performs a contrast examination using a contrast device, first, according to the part, the appropriate probe is selected to be positioned at the lesion location and the section, then the contrast mode of the device is entered, and the imaging parameters such as imaging frequency, gain and mechanical index MI (reflecting the intensity of the transmitted sound field) are adjusted according to the depth of the lesion. Next, the timer is started while the ultrasonic contrast agent is injected, and the entire process of the contrast agent micro-bubbles entering and exiting the lesion is observed and compared with the normal tissue around the lesion, and then a differential diagnosis is made on the benign and malignant properties of the lesion.

[0004] Due to the traditional acoustic wave diffraction phenomenon, the resolution limit of ultrasonic imaging is about half a wavelength, and doctors will be helpless when facing micro-vessels with a diameter of 10 μm, so an ultrahigh-resolution contrast imaging is proposed to enable ultrasonic to break through the resolution limit of traditional imaging. In addition, when doctors use the ultrahigh-resolution contrast function, they often pay more attention to the detailed information of the lesion area in the image, and thus hope to obtain a larger image for observation through the magnification function. The current ultrahigh-resolution contrast mode only has a simple magnification function, which magnifies the image in visual effect, and the image clarity and resolution are reduced after the image is magnified, which is not conducive to observing the micro-vascular information. SUMMARY

[0005] In one aspect of the present application, a super-resolution imaging method is provided, which comprises: controlling an ultrasonic probe to emit first ultrasonic waves to a target tissue, receiving echoes of the first ultrasonic waves to obtain first ultrasonic echo data, and generating and displaying a first tissue image according to the first ultrasonic echo data; selecting a super-resolution imaging region on the first tissue image; controlling the ultrasonic probe to emit second ultrasonic waves to the target tissue into which a contrast agent has been injected, receiving echoes of the second ultrasonic waves to obtain and store second ultrasonic echo data, processing the second ultrasonic echo data based on first imaging parameters to obtain first data, determining a first contrast agent microbubble recognition threshold based on the first data, processing the first data based on the first contrast agent microbubble recognition threshold to generate a first super-resolution contrast image corresponding to the super-resolution imaging region; displaying the first super-resolution contrast image; in response to a received user instruction to magnify the first super-resolution contrast image, processing the second ultrasonic echo data based on second imaging parameters to obtain second data, determining a second contrast agent microbubble recognition threshold based on the second data, processing the second data based on the second contrast agent microbubble recognition threshold to generate a second super-resolution contrast image corresponding to part or all of the super-resolution imaging region, wherein at least one parameter in the second imaging parameters has a value greater than a value of a same parameter in the first imaging parameters; and displaying the second super-resolution contrast image, which has a size greater than a size of an image portion in the first super-resolution contrast image corresponding to an imaging region of the second super-resolution contrast image and has a resolution not lower than a resolution of the image portion.

[0006] According to another aspect of the present application, a super-resolution imaging method is provided, which comprises: controlling an ultrasonic probe to emit second ultrasonic waves to a target tissue into which a contrast agent has been injected with first transmission parameters, receiving echoes of the second ultrasonic waves, processing the second ultrasonic echo data to obtain first data, determining a first contrast agent microbubble recognition threshold based on the first data, and processing the first data based on the first contrast agent microbubble recognition threshold to generate a first super-resolution contrast image; displaying the first super-resolution contrast image; determining a region to be magnified on the first super-resolution contrast image; in response to a received user instruction to magnify the first super-resolution contrast image, controlling the ultrasonic probe to emit third ultrasonic waves to the target tissue into which the contrast agent has been injected with second transmission parameters, receiving echoes of the third ultrasonic waves, processing the third ultrasonic echo data to obtain third data, determining a third microbubble recognition threshold based on the third data, and processing the third data based on the third microbubble recognition threshold to generate a third super-resolution contrast image corresponding to the region to be magnified; and displaying the third super-resolution contrast image.

[0007] According to still another aspect of the present application, a display method of a super-resolution image is provided, the method comprising: displaying a first tissue image of a target tissue; selecting a super-resolution imaging region on the first tissue image; after the target tissue is injected with a contrast agent, displaying a first super-resolution contrast image corresponding to the super-resolution imaging region, the first super-resolution contrast image having a first imaging parameter; in response to receiving a user instruction to zoom in the first super-resolution contrast image, displaying a second super-resolution contrast image corresponding to a region to be zoomed in on the first super-resolution contrast image, the second super-resolution contrast image having a second imaging parameter, wherein at least one parameter in the second imaging parameter has a value greater than a same parameter in the first imaging parameter, the second super-resolution contrast image has a size greater than a size of an image portion corresponding to the region to be zoomed in on the first super-resolution contrast image, and the second super-resolution contrast image has a resolution not lower than a resolution of the image portion.

[0008] According to still another aspect of the present application, an ultrasound imaging device is provided, the device comprising a transmit-receive circuit, an ultrasound probe, a processor, and a display, wherein: the transmit-receive circuit is configured to control the ultrasound probe to transmit ultrasound waves to a target object, receive echoes of the ultrasound waves, and obtain ultrasound echo data from the echoes; the processor is configured to control the transmit-receive circuit and perform the method described above to generate a first tissue image, a first super-resolution contrast image, and a second super-resolution contrast image; and the display is configured to display the first tissue image, the first super-resolution contrast image, and the second super-resolution contrast image.

[0009] The super-resolution imaging method of the present application first performs a first processing on raw data (i.e., second ultrasound echo data) used to generate a super-resolution imaging result by a first imaging parameter to generate a first super-resolution contrast image, and after receiving a user instruction to zoom in the image, performs a second processing on the raw data by a second imaging parameter. Since at least one parameter in the second imaging parameter has a value greater than a same parameter in the first imaging parameter, the finally generated second super-resolution contrast image has a size greater than a size of an image portion in the first super-resolution contrast image corresponding to an imaging region of the second super-resolution contrast image, and the second super-resolution contrast image has a resolution not lower than a resolution of the image portion. BRIEF DESCRIPTION OF DRAWINGS

[0010] The above and other objects, features and advantages of the present application will become more apparent from the following detailed description when taken in conjunction with the accompanying drawings in which:

[0011] Figure 1 A schematic flow chart of a super-resolution imaging method according to an embodiment of the present application is shown.

[0012] Figure 2 An example diagram showing a first tissue image, a super-resolution imaging region selected on the first tissue image, and a first super-resolution contrast image of the super-resolution imaging region is shown.

[0013] Figure 3 A schematic diagram showing increasing line density by changing the strategy of receiving line composites in a super-resolution imaging method according to an embodiment of the present application is shown.

[0014] Figure 4 An example diagram showing a first super-resolution contrast image in Figure 2 , an enlarged effect diagram of the first super-resolution contrast image, i.e., a second super-resolution contrast image is shown.

[0015] Figure 5 An example diagram showing a user interaction interface in a super-resolution imaging method according to an embodiment of the present application is shown.

[0016] Figure 6 A schematic flow chart of a super-resolution imaging method according to another embodiment of the present application is shown.

[0017] Figure 7 A schematic flow chart of a display method of a super-resolution image according to an embodiment of the present application is shown.

[0018] Figure 8 A schematic structural block diagram of an ultrasound imaging apparatus according to an embodiment of the present application is shown. DETAILED DESCRIPTION

[0019] In order to make the objects, technical solutions and advantages of the present application more apparent, the following will describe example embodiments of the present application in detail with reference to the accompanying drawings. Obviously, the described embodiments are only some of the embodiments of the present application, rather than all the embodiments of the present application, and it should be understood that the present application is not limited to the example embodiments described herein. Based on the embodiments of the present application described in the present application, all other embodiments obtained by those skilled in the art without creative effort should fall within the protection scope of the present application.

[0020] Figure 1 A schematic flowchart of the super-resolution imaging method 100 according to an embodiment of the present application is shown. As shown in the flowchart, the super-resolution imaging method 100 can include the following steps: Figure 1

[0021] At step S110, the ultrasound probe is controlled to emit first ultrasound waves to the target tissue, receive echoes of the first ultrasound waves to obtain first ultrasound echo data, and generate and display a first tissue image according to the first ultrasound echo data.

[0022] At step S120, a super-resolution imaging region is selected on the first tissue image.

[0023] At step S130, the ultrasound probe is controlled to emit second ultrasound waves to the target tissue injected with contrast agent, receive echoes of the second ultrasound waves to obtain and store second ultrasound echo data, process the second ultrasound echo data based on first imaging parameters to obtain first data, determine a first contrast agent microbubble recognition threshold based on the first data, and generate a first super-resolution contrast image corresponding to the super-resolution imaging region by processing the first data based on the first contrast agent microbubble recognition threshold.

[0024] At step S140, the first super-resolution contrast image is displayed.

[0025] At step S150, in response to a received user instruction to zoom in the first super-resolution contrast image, the second ultrasound echo data is processed based on second imaging parameters to obtain second data, a second contrast agent microbubble recognition threshold is determined based on the second data, and a second super-resolution contrast image corresponding to part or all of the super-resolution imaging region is generated by processing the second data based on the second contrast agent microbubble recognition threshold, wherein at least one parameter in the second imaging parameters has a value greater than a value of a same parameter in the first imaging parameters.

[0026] At step S160, the second super-resolution contrast image is displayed, the size of the second super-resolution contrast image is greater than the size of an image portion in the first super-resolution contrast image corresponding to an imaging region of the second super-resolution contrast image, and the resolution of the second super-resolution contrast image is not lower than the resolution of the image portion.

[0027] In an embodiment of the present application, the first ultrasound waves are emitted to the target tissue to generate a tissue image (i.e., the first tissue image) of the target tissue, so that a region of interest (i.e., the super-resolution imaging region) is selected on the tissue image, wherein the target tissue can or can not contain contrast agent.

[0028] ​The second ultrasound wave is emitted to the target tissue containing the contrast agent to obtain second ultrasound echo data for performing super-resolution imaging, and the part of the ultrasound echo data is mainly used for generating the super-resolution image and can also be used for generating the tissue image and / or the contrast image.

[0029] Specifically, the second ultrasound echo data can be processed based on the first imaging parameters (for example, including the first sampling rate, the first receiving line density, etc.) to obtain first data. The first data can be data for generating the multiple contrast-enhanced images or can be the multiple contrast-enhanced images. Since the contrast agent microbubbles in the contrast-enhanced images need to be identified to track the motion trajectory of the microbubbles, and the super-resolution contrast image is synthesized by superimposing the microbubble positioning points of several frames of contrast-enhanced images, the first contrast agent microbubble identification threshold for identifying the contrast agent microbubbles can be determined based on the first data, and the first data is processed based on the threshold (i.e., the contrast agent microbubble data in the first data is identified, the motion trajectory thereof is tracked, and the microbubble positioning points of several frames of contrast-enhanced images are superimposed) to generate and display the super-resolution contrast image (i.e., the first super-resolution contrast image corresponding to the selected super-resolution imaging region).

[0030] At this point, the user can see the generated first super-resolution contrast image on the display. Figure 2 That is, an example diagram of the first tissue image 210, the selected super-resolution imaging region 220 on the first tissue image 210, and the first super-resolution contrast image 230 of the super-resolution imaging region 220 is shown.

[0031] Since the user often pays more attention to the detail information of the lesion region in the first super-resolution contrast image 230, it is desired to obtain a larger image through the zoom-in function to observe. The existing zoom-in method can only visually zoom in the super-resolution contrast image 230, but the zoomed-in image has reduced clarity and resolution relative to the super-resolution contrast image 230, which is not conducive to observing the tiny blood vessel information.

[0032] To this end, the application provides a new zooming solution. Specifically, a user can input a user instruction for zooming in on a first super-resolution contrast image, and in response to receiving the user instruction, the second ultrasound echo data is processed based on second imaging parameters (e.g., including a second sampling rate, a second receive line density, etc.) to obtain second data. The second data can be data for generating a plurality of contrast-enhanced images or can be the plurality of contrast-enhanced images. Since the contrast agent microbubbles in the contrast-enhanced images need to be identified to track the motion trajectory of the microbubbles, and the super-resolution contrast image is synthesized by superimposing the microbubble positioning points of a plurality of contrast-enhanced images, a second contrast agent microbubble identification threshold for identifying the contrast agent microbubbles can be determined based on the second data, the second data is processed based on the threshold (i.e., identifying the contrast agent microbubble data in the second data, tracking the motion trajectory of the microbubbles, and superimposing the microbubble positioning points of a plurality of contrast-enhanced images), and thus a super-resolution contrast image (i.e., a second super-resolution contrast image) is generated and displayed.

[0033] In the embodiments of the application, the value of at least one parameter in the second imaging parameters is greater than the value of the same parameter in the first imaging parameters. For example, the first imaging parameters include a first sampling rate and a first receive line density, and the second imaging parameters include a second sampling rate and a second receive line density, wherein: the second sampling rate is greater than the first sampling rate; and / or, the second receive line density is greater than the first receive line density.

[0034] For example, when the second sampling rate is greater than the first sampling rate, the number of longitudinal points required for finally generating the super-resolution contrast image (i.e., the second super-resolution contrast image) is increased, so that the size of the second super-resolution contrast image finally generated is greater than the size of the image portion in the first super-resolution contrast image corresponding to the imaging area of the second super-resolution contrast image, and the resolution of the second super-resolution contrast image is not lower than the resolution of the image portion.

[0035] For another example, when the second receive line density is greater than the first receive line density, the number of transverse points required for finally generating the super-resolution contrast image (i.e., the second super-resolution contrast image) is increased, so that the size of the second super-resolution contrast image finally generated is greater than the size of the image portion in the first super-resolution contrast image corresponding to the imaging area of the second super-resolution contrast image, and the resolution of the second super-resolution contrast image is not lower than the resolution of the image portion. Figure 3 That is, a schematic diagram showing that the line density is increased by changing the strategy of receive line compounding.

[0036] For example, when the second sampling rate is greater than the first sampling rate and the second receiving line density is greater than the first receiving line density, the number of longitudinal points and the number of transverse points required for finally generating the super-resolution angiogram image (i.e., the second super-resolution angiogram image) are increased, so that the size of the finally generated second super-resolution angiogram image is greater than the size of the image portion in the first super-resolution angiogram image corresponding to the imaging area of the second super-resolution angiogram image, and the resolution of the second super-resolution angiogram image is not lower than the resolution of the image portion.

[0037] Therefore, due to the fact that the value of at least one parameter in the second imaging parameter is greater than the value of the same parameter in the aforementioned first imaging parameter, the finally obtained second data has more image points relative to the first data, so that the size of the finally generated second super-resolution angiogram image is greater than the size of the image portion in the first super-resolution angiogram image corresponding to the imaging area of the second super-resolution angiogram image, and the resolution of the second super-resolution angiogram image is not lower than the resolution of the image portion.

[0038] Figure 4 That is, the enlarged effect diagram of the first super-resolution angiogram image 230 in Figure 2 is shown, i.e., the second super-resolution angiogram image 430. In combination with Figure 2 and Figure 4 , the above method realizes the enlargement of the first super-resolution angiogram image, and the size of the enlarged image is increased, but the resolution is not decreased, which is more convenient for the user to observe the detailed information of the lesion area.

[0039] Therefore, according to the super-resolution imaging method 100 of the embodiment of the present application, the original data (i.e., the second ultrasonic echo data) used for generating the super-resolution imaging result is first processed by the first imaging parameter to generate the first super-resolution angiogram image, and after receiving the user instruction of the enlarged image, the original data is processed by the second imaging parameter. Due to the fact that the value of at least one parameter in the second imaging parameter is greater than the value of the same parameter in the first imaging parameter, the size of the finally generated second super-resolution angiogram image is greater than the size of the image portion in the first super-resolution angiogram image corresponding to the imaging area of the second super-resolution angiogram image, and the resolution of the second super-resolution angiogram image is not lower than the resolution of the image portion.

[0040] In the embodiments of the present application, after the first super-resolution contrast image is displayed, the method 100 can further include: determining a region to be zoomed in on the first super-resolution contrast image, wherein the region to be zoomed in on is part or all of the super-resolution imaging region; the step S150 of processing the second ultrasound echo data based on the second imaging parameter to obtain second data, and determining a second contrast agent microbubble recognition threshold based on the second data, and processing the second data based on the second contrast agent microbubble recognition threshold to generate a second super-resolution contrast image corresponding to part or all of the super-resolution imaging region can include: obtaining second ultrasound echo data of the region to be zoomed in, processing the second ultrasound echo data of the region to be zoomed in based on the second imaging parameter to obtain second data, and determining a second contrast agent microbubble recognition threshold based on the second data, and processing the second data based on the second contrast agent microbubble recognition threshold to generate a second super-resolution contrast image corresponding to the region to be zoomed in.

[0041] In this embodiment, by determining the region to be zoomed in on the first super-resolution contrast image, obtaining data corresponding to the region to be zoomed in from the second ultrasound echo data, and processing the data based on the second imaging parameter to obtain second data, and then obtaining the second super-resolution contrast image, the zooming in on part of the first super-resolution contrast image can be realized, and the zooming in on the entire first super-resolution contrast image can also be realized, and different needs of users can be flexibly met.

[0042] Exemplarily, the region to be zoomed in can be obtained based on user input, for example, the user circles the region to be zoomed in on the first super-resolution contrast image, and an identifier of the region to be zoomed in can be displayed on the first super-resolution contrast image to more clearly show the position of the region to be zoomed in.

[0043] In the embodiments of the present application, the processing of the second data based on the second contrast agent microbubble recognition threshold in the step S150 can further include interpolation processing. By interpolating the second data, the number of data points can be further increased, and thus the definition and resolution of the zoomed-in super-resolution contrast image can be further improved.

[0044] In the embodiments of the present application, the user instruction in the step S150 includes a zooming-in multiple of the first super-resolution contrast image, and the method 100 further includes: determining the second imaging parameter based on the zooming-in multiple and the first imaging parameter. In this embodiment, the user instruction includes a specific zooming-in multiple, and the second imaging parameter can be determined according to the specific zooming-in multiple. In another embodiment, the zooming-in multiple can not be included in the user instruction, and then the second imaging parameter can be determined according to a system default zooming-in multiple.

[0045] In one example, the user instruction can be obtained based on a user interaction interface, where the user interaction interface can provide a selection control for the user to select a zoom factor or provide an input control for the user to input a zoom factor. In this example, the user instruction is obtained through the user interaction interface. Figure 5 That is, a schematic diagram of a user interaction interface is shown. As shown, a "Holo Msc" button represents a super-resolution contrast mode, and the user can click the button to start entering the super-resolution contrast imaging mode to perform super-resolution contrast imaging. An "ROI" button represents a super-resolution imaging region, and the user can click the button to select a super-resolution imaging region on the first tissue image, and subsequently, the ultrasound echo data (i.e., the second ultrasound echo data described above) of the region will be automatically collected and stored for super-resolution imaging. A "Zoom" button represents a zoom factor input control, and the user can click the control to input a desired zoom factor to zoom the first super-resolution contrast image to obtain the second super-resolution contrast image, as described above. Figure 5 In the example shown, the zoom factor is obtained in the form of an input control, and in other examples, the zoom factor can also be obtained in other ways, such as a selection control such as a drop-down box, etc. Figure 5

[0046] In another example, the user instruction is obtained based on a user interaction button, which provides zoom factor levels for the user to select or input a zoom factor. In this example, the user interaction is provided in the form of a physical button, relative to the previous example. For example, the physical button can be located on the user interaction device of the ultrasound device. The user interaction button here can provide multiple zoom levels, for example, in the form of a rotary knob, different rotary knob positions represent different zoom levels, or different buttons represent different levels, etc. In addition, a button to start voice input can also be provided, and after clicking the button, the user can directly input the desired zoom factor through voice input.

[0047] In one embodiment, the second super-resolution contrast image and the first super-resolution contrast image can be displayed in different display regions of the display interface / display screen. In this embodiment, both the second super-resolution contrast image and the first super-resolution contrast image can be displayed simultaneously for the user to observe and compare.

[0048] ​In one embodiment, as described above, the second ultrasound echo data can also be used to generate a tissue image. In order to distinguish from the first tissue image generated based on the first ultrasound echo data, the tissue image generated based on the second ultrasound echo data is referred to as a second tissue image. The second tissue image can be displayed in a first display area of the display interface / display screen, and the first super-resolution contrast image and the second tissue image can be simultaneously displayed in a second display area, and the first super-resolution contrast image is displayed as a foreground image superimposed on the second tissue image. The first display area and the second display area are different display areas.

[0049] In one example, after the second super-resolution contrast image is generated, the first super-resolution contrast image can be replaced by the second super-resolution contrast image in the second display area and the second super-resolution contrast image can be displayed. In this example, the first super-resolution contrast image and the second super-resolution contrast image are displayed in the same display area, and the two images are not displayed simultaneously. This can be applied to a scenario in which the display interface / display screen is small.

[0050] In another example, after the second super-resolution contrast image is generated, the second super-resolution contrast image can be displayed in a third display area, wherein the third display area is different from the second display area, so that the second super-resolution contrast image and the first super-resolution contrast image can be simultaneously displayed without blocking each other. In this example, the first super-resolution contrast image and the second super-resolution contrast image are displayed in different display areas, and the two images can be simultaneously displayed without blocking each other, so that a user can observe and compare.

[0051] The above examples illustrate the super-resolution imaging method 100 according to one embodiment of the present application. Based on the above description, the super-resolution imaging method 100 according to the embodiment of the present application first processes the original data (i.e., the second ultrasound echo data) for generating a super-resolution imaging result by a first imaging parameter to generate a first super-resolution contrast image. After receiving a user instruction to zoom in, the original data is processed by a second imaging parameter. Since the value of at least one parameter in the second imaging parameter is greater than the value of the same parameter in the first imaging parameter, the size of the finally generated second super-resolution contrast image is greater than the size of the image part in the first super-resolution contrast image corresponding to the imaging area of the second super-resolution contrast image, and the resolution of the second super-resolution contrast image is not lower than the resolution of the image part.

[0052] The super-resolution imaging method according to another embodiment of the present application will be described below. Figure 6 The super-resolution imaging method according to another embodiment of the present application will be described below. Figure 6 A schematic flowchart of a super-resolution imaging method 600 according to another embodiment of the present application is shown. As shown in the figure, the super-resolution imaging method 600 can include the following steps: Figure 6 The super-resolution imaging method according to another embodiment of the present application will be described below.

[0053] At step S610, the ultrasound probe is controlled to transmit second ultrasound waves to the target tissue injected with the contrast agent at a first transmission parameter, receive echoes of the second ultrasound waves, process the second ultrasound echo data to obtain first data, and determine a first contrast agent microbubble recognition threshold based on the first data, and process the first data based on the first contrast agent microbubble recognition threshold to generate a first super-resolution contrast image.

[0054] At step S620, the first super-resolution contrast image is displayed.

[0055] At step S630, a region to be zoomed in is determined on the first super-resolution contrast image.

[0056] At step S640, in response to the received user instruction to zoom in the first super-resolution contrast image, the ultrasound probe is controlled to transmit third ultrasound waves to the target tissue injected with the contrast agent at a second transmission parameter, receive echoes of the third ultrasound waves, process the third ultrasound echo data to obtain third data, determine a third microbubble recognition threshold based on the third data, and process the third data based on the third microbubble recognition threshold to generate a third super-resolution contrast image corresponding to the region to be zoomed in.

[0057] At step S650, the third super-resolution contrast image is displayed.

[0058] The super-resolution imaging method 600 according to the embodiments of the present application and the super-resolution imaging method 100 according to the embodiments of the present application described above are both to obtain a zoomed-in super-resolution contrast image with no reduction in clarity and resolution, and the main difference lies in that: after receiving the user instruction to zoom in the first super-resolution contrast image, the super-resolution imaging method 100 obtains the second ultrasound echo data used to generate the first super-resolution contrast image, reprocesses the second ultrasound echo data to obtain second data, and generates a second super-resolution contrast image based on the second data; while the super-resolution imaging method 600, after receiving the user instruction to zoom in the first super-resolution contrast image, no longer uses the second ultrasound echo data used to generate the first super-resolution contrast image, but transmits third ultrasound waves to the target tissue at a transmission parameter different from that of the second ultrasound waves, obtains new ultrasound echo data, i.e., third ultrasound echo data, and then obtains third data based on the third data, and generates a third super-resolution contrast image based on the third data, which is the zoomed-in result of the region to be zoomed in in the first super-resolution contrast image.

[0059] Specifically, first, the ultrasound probe is controlled to emit second ultrasound waves with a first emission parameter to the target tissue injected with contrast agent, to obtain second ultrasound echo data, and the second ultrasound echo data is processed to obtain first data. The first data can be data used to generate multiple contrast-enhanced images or can be multiple contrast-enhanced images. Since it is necessary to identify contrast agent microbubbles in the contrast-enhanced images, to track and locate the motion trajectory of the microbubbles, and to superimpose the microbubble locating points of several frames of contrast-enhanced images to synthesize a super-resolution contrast image, a first contrast agent microbubble identification threshold for identifying the contrast agent microbubbles can be determined based on the first data, and the first data is processed based on the threshold (i.e., the contrast agent microbubble data in the first data is identified, the motion trajectory thereof is tracked and located, and the microbubble locating points of several frames of contrast-enhanced images are superimposed), so as to generate and display a super-resolution contrast image (i.e., a first super-resolution contrast image).

[0060] After a user instruction of zooming in on the first super-resolution contrast image is input, in response to receiving the user instruction, the ultrasound probe can be controlled to emit third ultrasound waves with a second emission parameter to the target tissue injected with contrast agent, to obtain third ultrasound echo data, and the third ultrasound echo data is processed to obtain third data. The third data can be data used to generate multiple contrast-enhanced images or can be multiple contrast-enhanced images. Since it is necessary to identify contrast agent microbubbles in the conventional contrast images, to track and locate the motion trajectory of the microbubbles, and to superimpose the microbubble locating points of several frames of contrast-enhanced images to synthesize a super-resolution contrast image, a third contrast agent microbubble identification threshold for identifying the contrast agent microbubbles can be determined based on the third data, and the third data is processed based on the threshold (i.e., the contrast agent microbubble data in the third data is identified, the motion trajectory thereof is tracked and located, and the microbubble locating points of several frames of contrast-enhanced images are superimposed), so as to generate and display a super-resolution contrast image (i.e., a third super-resolution contrast image).

[0061] In the embodiments of the present application, the second emission parameter is different from the first emission parameter, and the size of the finally generated third super-resolution contrast image is greater than that of an image part in the first super-resolution contrast image corresponding to the imaging area of the third super-resolution contrast image, and the definition of the third super-resolution contrast image is not lower than that of the image part. Therefore, the super-resolution imaging method 600 according to the embodiments of the present application can realize the effect of zooming in on the super-resolution contrast image without reducing the image definition by changing the emission parameter.

[0062] Further, the second emission parameter is different from the first emission parameter, and the quality of the finally generated third super-resolution contrast image is higher than that of the first super-resolution contrast image. In this embodiment, by changing the emission parameter, not only can the super-resolution contrast image be zoomed in, but also the quality of the zoomed-in image is higher, which is more conducive to the user to observe the lesion details.

[0063] In the embodiments of the present application, the region to be enlarged determined on the first super-resolution contrast image can be a partial region of the first super-resolution contrast image, or can be the entire region of the first super-resolution contrast image, thereby flexibly meeting different needs of the user.

[0064] For example, the region to be enlarged can be obtained based on user input, for example, the user circles the region to be enlarged on the first super-resolution contrast image, and the identification of the region to be enlarged can be displayed on the first super-resolution contrast image to more clearly show the position of the region to be enlarged.

[0065] In the embodiments of the present application, the processing of the third data based on the third contrast agent microbubble recognition threshold in step S640 can further include interpolation processing. By interpolating the third data, the number of data points can be further increased, thereby further improving the clarity and resolution of the enlarged super-resolution contrast image.

[0066] In the embodiments of the present application, the user instruction in step S640 can include a magnification of the first super-resolution contrast image, and the method 100 can further include determining a second emission parameter based on the magnification and the first emission parameter. In this embodiment, the user instruction contains a specific magnification, and the second emission parameter can be determined according to the specific magnification. In another embodiment, the user instruction can also not include the magnification, and then the second emission parameter can be determined according to the system default magnification.

[0067] In one example, the user instruction can be obtained based on a user interaction interface, wherein the user interaction interface can provide a selection control for the user to select a magnification or provide an input control for the user to input a magnification. In this example, the user instruction is obtained through the user interaction interface.

[0068] In another example, the user instruction is obtained based on a user interaction button, and the user interaction button provides magnification gears for the user to select or input a magnification. Relative to the previous example, in this example, the user interaction is provided in the form of a physical button. For example, the physical button can be located on the user interaction device of the ultrasound device. The user interaction button here can provide multiple magnification gears, for example, in the form of a knob to provide gears, different knob positions represent different magnification gears, or different buttons represent different gears, etc. In addition, a button to start voice input can also be provided, after clicking the button, the user can directly input the desired magnification through voice input.

[0069] In one embodiment, the third super-resolution contrast image and the first super-resolution contrast image can be displayed in different display regions of the display interface / display screen. In this embodiment, the third super-resolution contrast image and the first super-resolution contrast image can be displayed simultaneously so as to be observed by the user in comparison.

[0070] In one embodiment, as described above, the third ultrasound echo data can also be used to generate a tissue image. The tissue image can be displayed in a first display region of the display interface / display screen, the first super-resolution contrast image and the tissue image can be displayed simultaneously in a second display region, and the first super-resolution contrast image is displayed as a foreground image superimposed on the tissue image. Herein, the first display region and the second display region are different display regions.

[0071] In one example, after the third super-resolution contrast image is generated, the first super-resolution contrast image can be replaced by the third super-resolution contrast image in the second display region and the third super-resolution contrast image is displayed. In this example, the first super-resolution contrast image and the third super-resolution contrast image are displayed in the same display region, and the two are not displayed simultaneously, which can be applied to the scenario that the display interface / display screen is small.

[0072] In another example, after the third super-resolution contrast image is generated, the third super-resolution contrast image can be displayed in a third display region, wherein the third display region is different from the second display region, so that the third super-resolution contrast image and the first super-resolution contrast image can be displayed simultaneously without blocking each other. In this example, the first super-resolution contrast image and the third super-resolution contrast image are displayed in different display regions, and the two can be displayed simultaneously without blocking each other so as to be observed by the user in comparison.

[0073] The above examples exemplarily show the super-resolution imaging method 600 according to one embodiment of the present application. Based on the above description, the super-resolution imaging method 600 according to the embodiment of the present application first obtains data (i.e., the second ultrasound echo data) for generating a super-resolution imaging result by using a first emission parameter, processes the data, generates a first super-resolution contrast image, and after receiving a user instruction of zooming the image, obtains data (i.e., the third ultrasound echo data) for generating a super-resolution imaging result by using a second emission parameter. Since the second emission parameter is different from the first emission parameter, and can make the size of the finally generated third super-resolution contrast image greater than the size of an image part in the first super-resolution contrast image corresponding to the imaging region of the third super-resolution contrast image, and the definition of the third super-resolution contrast image is not lower than the definition of the image part, the super-resolution contrast image can be zoomed without reducing the image quality, which is beneficial to the user to observe the lesion details.

[0074] In further embodiments of the present application, the aforementioned methods 100 and 600 can be combined with each other, that is, after receiving a user instruction to enlarge the first super-resolution contrast image, a third ultrasound wave is emitted to the target tissue with different emission parameters from those used to emit the second ultrasound wave, obtaining new ultrasound echo data, that is, third ultrasound echo data; the third ultrasound echo data is processed with third imaging parameters to obtain fourth data, based on which a fourth contrast agent microbubble recognition threshold is determined, and based on the fourth contrast agent microbubble recognition threshold, the fourth data is processed to generate a fourth super-resolution contrast image corresponding to the partial or entire super-resolution imaging region, wherein the third imaging parameters are different from the second imaging parameters, and the second emission parameters are different from the first emission parameters, which can make the size of the fourth super-resolution contrast image greater than that of an image portion of the first super-resolution contrast image corresponding to the imaging region of the fourth super-resolution contrast image, and the resolution of the fourth super-resolution contrast image is not lower than that of the image portion. In this embodiment, the effect of enlarging the super-resolution contrast image without reducing the image resolution can be achieved by changing both the imaging parameters and the emission parameters.

[0075] The display method of a super-resolution image according to an embodiment of the present application will be described below in conjunction with Figure 7 The display method of a super-resolution image according to an embodiment of the present application will be described below in conjunction with Figure 7 A schematic flowchart of a display method 700 of a super-resolution image according to an embodiment of the present application is shown. As shown in the flowchart, the display method 700 of a super-resolution image can include the following steps: Figure 7

[0076] In step S710, a first tissue image of the target tissue is displayed.

[0077] In step S720, a super-resolution imaging region is selected on the first tissue image.

[0078] In step S730, after the target tissue is injected with a contrast agent, a first super-resolution contrast image corresponding to the super-resolution imaging region is displayed, and the imaging parameters of the first super-resolution contrast image are first imaging parameters.

[0079] In step S740, in response to receiving a user instruction to enlarge the first super-resolution contrast image, a second super-resolution contrast image corresponding to a region to be enlarged on the first super-resolution contrast image is displayed, and the imaging parameters of the second super-resolution contrast image are second imaging parameters, wherein at least one parameter in the second imaging parameters has a value greater than that of the same parameter in the first imaging parameters, the size of the second super-resolution contrast image is greater than that of an image portion of the first super-resolution contrast image corresponding to the region to be enlarged, and the resolution of the second super-resolution contrast image is not lower than that of the image portion.

[0080] ​The display method 700 of the super-resolution image according to the embodiments of the present application is generally similar to the super-resolution imaging method 100 according to the embodiments of the present application described above, but the super-resolution imaging method 100 describes the super-resolution imaging method from the aspects of workflow and algorithm, while the display method 700 of the super-resolution image describes the method from the perspective of user view. Therefore, the display method 700 of the super-resolution image can also obtain a first super-resolution angiogram based on the first imaging parameter, and after receiving the user instruction of the zoomed image, obtain a zoomed super-resolution image, i.e., a second super-resolution angiogram, based on the second imaging parameter, the size of the second super-resolution angiogram is greater than the size of an image part in the first super-resolution angiogram corresponding to the imaging area of the second super-resolution angiogram, and the definition of the second super-resolution angiogram is not lower than the definition of the image part.

[0081] In the embodiments of the present application, after the target tissue is injected with the contrast agent, the first conventional angiogram can be displayed; and after the first conventional angiogram is displayed, the first super-resolution angiogram can be displayed.

[0082] In the embodiments of the present application, after the first super-resolution angiogram is displayed, the method 700 can further include determining a region to be zoomed on the first super-resolution angiogram, wherein the region to be zoomed is part or all of the super-resolution imaging area; and the finally obtained second super-resolution angiogram is a zoomed image corresponding to the region to be zoomed.

[0083] In this embodiment, by determining the region to be zoomed on the first super-resolution angiogram, the zooming of part of the first super-resolution angiogram or the zooming of the entire first super-resolution angiogram can be realized, thereby flexibly meeting different needs of users.

[0084] For example, the region to be zoomed can be obtained based on user input, for example, the user circles the region to be zoomed on the first super-resolution angiogram, and the identification of the region to be zoomed can be displayed on the first super-resolution angiogram to more clearly show the position of the region to be zoomed.

[0085] In the embodiments of the present application, the user instruction of the step S740 includes the zooming multiple of the first super-resolution angiogram, and the method 700 further includes determining the second imaging parameter based on the zooming multiple and the first imaging parameter. In this embodiment, the user instruction contains the specific zooming multiple, and the second imaging parameter can be determined according to the specific zooming multiple. In another embodiment, the user instruction can also not include the zooming multiple, and then the second imaging parameter can be determined according to the system default zooming multiple.

[0086] In one example, the user instruction can be acquired based on a user interaction interface, where the user interaction interface can provide a selection control for the user to select a magnification factor or provide an input control for the user to input a magnification factor. In this example, the user instruction is acquired through the user interaction interface. Figure 5 i.e. a schematic view of the user interaction interface is shown, Figure 5 The specific content is as described above, which will not be repeated here.

[0087] In another example, the user instruction is acquired based on a user interaction button, which provides magnification factor gears for the user to select or input a magnification factor. In this example, the user interaction is provided in the form of a physical button relative to the previous example. For example, the physical button can be located on the user interaction device of the ultrasound device. The user interaction button here can provide multiple magnification gears, such as providing gears in the form of a knob, where different knob positions represent different magnification gears, or different buttons represent different gears, etc. In addition, a button for starting voice input can also be provided, and after clicking the button, the user can directly input the desired magnification factor through voice input.

[0088] In one embodiment, the second super-resolution contrast image and the first super-resolution contrast image can be displayed in different display areas of the display interface / display screen. In this embodiment, the second super-resolution contrast image and the first super-resolution contrast image can be displayed simultaneously for the user to observe and compare.

[0089] In one embodiment, after the target tissue is injected with contrast agent, the second tissue image can be displayed in the first display area of the display interface / display screen, and the first super-resolution contrast image and the second tissue image can be simultaneously displayed in the second display area, and the first super-resolution contrast image is displayed as a foreground image superimposed on the second tissue image. Wherein, the first display area and the second display area are different display areas.

[0090] In one example, after the second super-resolution contrast image is generated, the first super-resolution contrast image can be replaced by the second super-resolution contrast image in the second display area and the second super-resolution contrast image can be displayed. In this example, the first super-resolution contrast image and the second super-resolution contrast image are displayed in the same display area, and they are not displayed at the same time, which can be applied to the scenario where the display interface / display screen is small.

[0091] In another example, after the second super-resolution contrast image is generated, it can be displayed in a third display area. This third display area is different from the second display area, allowing the second and first super-resolution contrast images to be displayed simultaneously without obscuring each other. In this example, the first and second super-resolution contrast images are displayed in different display areas, allowing them to be displayed simultaneously without obscuring each other, facilitating comparison and observation by the user.

[0092] The above exemplarily illustrates a super-resolution imaging method 700 according to an embodiment of this application. Based on the above description, the super-resolution imaging method 700 according to the embodiment of this application can obtain a first super-resolution imaging image based on first imaging parameters, and after receiving a user instruction to magnify the image, obtain a magnified super-resolution image, i.e., a second super-resolution imaging image, based on second imaging parameters. The size of the second super-resolution imaging image is larger than the size of the image portion corresponding to the imaging area of ​​the second super-resolution imaging image in the first super-resolution imaging image, and the sharpness of the second super-resolution imaging image is not lower than the sharpness of the image portion.

[0093] The following is combined with Figure 8 Describes an ultrasound imaging apparatus provided according to another aspect of this application. Figure 8 A schematic structural block diagram of an ultrasound imaging apparatus 800 according to an embodiment of this application is shown. Figure 8 As shown, the ultrasound imaging device 800 may include a transmit-receive circuit 810, an ultrasound probe 820, a processor 830, and a display 840. Specifically: the transmit-receive circuit 810 controls the ultrasound probe 820 to emit ultrasound waves towards a target object, receives the echoes of the ultrasound waves, and acquires ultrasound echo signals from the echoes; the processor 830 controls the transmit-receive circuit and executes the methods 100, 600, or 700 described above according to embodiments of this application to generate a first tissue image, a first super-resolution contrast image, and a second super-resolution contrast image. The display 840 displays the first tissue image, the first super-resolution contrast image, and the second super-resolution contrast image. Methods 100, 600, and 700 according to embodiments of this application have been described in detail above. Those skilled in the art can understand the structure and operation of the ultrasound imaging device 800 in conjunction with the foregoing description; for brevity, further details are omitted here.

[0094] In addition, according to an embodiment of the present application, a storage medium is also provided, on which program instructions are stored, and the program instructions are used to perform corresponding steps of the super-resolution imaging method or the display method of the super-resolution image according to an embodiment of the present application when the program instructions are run by a computer or a processor. The storage medium may, for example, include a memory card of a smart phone, a storage component of a tablet computer, a hard disk of a personal computer, a read-only memory (ROM), an erasable programmable read-only memory (EPROM), a portable compact disc read-only memory (CD-ROM), a USB memory, or any combination of the above storage media. The computer-readable storage medium can be any combination of one or more computer-readable storage media.

[0095] In addition, according to an embodiment of the present application, a computer program is also provided, which can be stored on a cloud or a local storage medium. The computer program is used to perform corresponding steps of the super-resolution imaging method or the display method of the super-resolution image according to an embodiment of the present application when the computer program is run by a computer or a processor.

[0096] Based on the above description, the super-resolution imaging method and the display method of the super-resolution image according to an embodiment of the present application first obtain a first super-resolution contrast image, and after receiving a user instruction to zoom in the image, obtain a zoomed-in super-resolution image, i.e., a second super-resolution contrast image. The size of the second super-resolution contrast image is greater than that of an image part in the first super-resolution contrast image corresponding to an imaging area of the second super-resolution contrast image, and the definition of the second super-resolution contrast image is not lower than that of the image part, thereby facilitating the user to observe the lesion details.

[0097] Although the example embodiments have been described herein with reference to the accompanying drawings, it is to be understood that the example embodiments are only exemplary and are not intended to limit the scope of the present application. Those of ordinary skill in the art can make various changes and modifications without departing from the scope and spirit of the present application. All such changes and modifications are intended to be included within the scope of the present application as claimed in the appended claims.

[0098] Those of ordinary skill in the art can realize that the units and algorithm steps of each example described in connection with the embodiments disclosed herein can be realized by electronic hardware, or a combination of computer software and electronic hardware. Whether the functions are performed by hardware or software depends on the specific application and design constraints of the technical solution. Those of ordinary skill in the art can use different methods to implement the described functions for each specific application, but such implementation should not be considered beyond the scope of the present application.

[0099] In several embodiments provided by the present application, it should be understood that the disclosed apparatus and methods can be implemented in other ways. For example, the above-described apparatus embodiments are merely schematic, and the division of units is merely a logical function division. In actual implementation, another division manner can be used, for example, a plurality of units or components can be combined or integrated into another apparatus, or some features can be omitted or not implemented.

[0100] In the specification provided herein, a large number of specific details are described. However, it can be understood that the embodiments of the present application can be practiced without these specific details. In some examples, well-known methods, structures and techniques are not described in detail in order not to obscure the understanding of the present specification.

[0101] Similarly, it should be appreciated that, in the description of the exemplary embodiments of the present application, various features of the present application are sometimes grouped together in a single embodiment, figure, or description of a related aspect. This is done for the purpose of clarity in understanding the present application. However, it should be understood that the method of the present application is not limited in this manner. In accordance with the application, features from different embodiments can be combined to make or implement a different embodiment of the present application. Therefore, the following claims are hereby expressly intended to include all possible combinations of the features described herein.

[0102] Those of skill in the art will understand that, in addition to the features described herein, all of the features of the application described and illustrated herein, including both the methods and the apparatuses, can be combined in any combination. Each of the features disclosed in this specification (including the claims, abstract, and drawings) can be replaced by alternative features that serve the same, equivalent or a similar purpose, unless expressly stated otherwise. Thus, unless expressly stated otherwise, each feature disclosed in this specification (including the claims, abstract and drawings) is a description of a specific embodiment of the application.

[0103] Furthermore, those of skill in the art will appreciate that the features of the various embodiments can be combined with features of other embodiments, as can be desired. Thus, the foregoing description of the embodiments of the application is by way of example only, and other embodiments of the application are within the scope of the application.

[0104] The various component embodiments of the present application can be implemented in hardware, or as software modules running in one or more processors, or combinations thereof. Those skilled in the art will appreciate that some or all of the functionality of some of the modules in the item analysis apparatus according to embodiments of the present application can be implemented in practice using a microprocessor or a digital signal processor (DSP). The present application can also be implemented as a program (for example, a computer program and a computer program product) for executing some or all of the methods described herein. Such a program implementing the present application can be stored on a computer-readable medium, or can be in the form of one or more signals. Such a signal can be downloaded from an Internet website, or provided on a carrier signal, or in any other form.

[0105] It should be noted that the above-mentioned embodiments illustrate rather than limit the application, and that one skilled in the art will be able to design many alternative embodiments without departing from the scope of the appended claims. In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The word 'comprising' does not exclude the presence of elements or steps other than those listed in a claim. The word 'a' or 'an' preceding an element does not exclude the presence of a plurality of such elements. The application can be implemented by means of hardware comprising several distinct elements, and by means of a suitably programmed computer. In a unitary claim, several of the devices, apparatuses or means, if any, can be implemented by one and the same item of hardware. The use of the words 'first','second' and 'third', etc. do not imply any order but rather are used for naming purposes only. Further, the word'step' can not imply any order and can not necessarily be construed to refer to a sequence of steps.

[0106] Any discussion of documents, acts, materials, devices, articles or the like that has been included in the present summary is not to be taken as an admission that any or all of these matters form part of the prior art base or were common general knowledge in the field relevant to the present application, as it exists worldwide at the priority date of each claim of this application.

Claims

1. A super-resolution imaging method, characterized by, The method comprises: controlling an ultrasonic probe to emit first ultrasonic waves to a target tissue, receiving echoes of the first ultrasonic waves to obtain first ultrasonic echo data, and generating and displaying a first tissue image according to the first ultrasonic echo data; selecting an ultrahigh-resolution imaging region on the first tissue image; controlling the ultrasonic probe to emit second ultrasonic waves to the target tissue into which a contrast agent has been injected, receiving echoes of the second ultrasonic waves to obtain and store second ultrasonic echo data, processing the second ultrasonic echo data based on first imaging parameters to obtain first data, determining a first contrast agent microbubble recognition threshold based on the first data, processing the first data based on the first contrast agent microbubble recognition threshold to generate a first ultrahigh-resolution contrast image corresponding to the ultrahigh-resolution imaging region; displaying the first ultrahigh-resolution contrast image; in response to a received user instruction to zoom in on the first ultrahigh-resolution contrast image, processing the second ultrasonic echo data based on second imaging parameters to obtain second data, determining a second contrast agent microbubble recognition threshold based on the second data, and processing the second data based on the second contrast agent microbubble recognition threshold to generate a second ultrahigh-resolution contrast image corresponding to part or all of the ultrahigh-resolution imaging region, wherein at least one parameter in the second imaging parameters has a value greater than a same parameter in the first imaging parameters; displaying the second ultrahigh-resolution contrast image, which has a size greater than that of an image portion in the first ultrahigh-resolution contrast image corresponding to an imaging region of the second ultrahigh-resolution contrast image and a resolution not lower than that of the image portion.

2. The method of claim 1, wherein: the first imaging parameters comprise a first sampling rate and a first receive line density; the second imaging parameters comprise a second sampling rate and a second receive line density; wherein the second sampling rate is greater than the first sampling rate; and / or the second receive line density is greater than the first receive line density.

3. The method of claim 1, wherein, processing the second data based on the second contrast agent microbubble recognition threshold comprises interpolation processing.

4. The method according to any one of claims 1-3, characterized by, the user instruction includes a zoom-in multiple of the first ultrahigh-resolution contrast image, and the method further comprises: determining the second imaging parameters based on the zoom-in multiple and the first imaging parameters.

5. The method of claim 4, wherein, the user instruction is obtained based on a user interaction interface, wherein the user interaction interface provides a selection control for a user to select a zoom-in multiple or an input control for a user to input a zoom-in multiple.

6. The method of claim 4, wherein, the user instruction is obtained based on a user interaction key, which provides a zoom-in multiple gear for a user to select or input a zoom-in multiple, and the input includes voice input.

7. The method according to any one of claims 1-3, characterized by, The method further comprises: after obtaining the second ultrasonic echo data, generating a first conventional contrast image based on the second ultrasonic echo data and displaying the first conventional contrast image.

8. The method according to any one of claims 1-7, characterized by, the second ultrahigh-resolution contrast image and the first ultrahigh-resolution contrast image are displayed in different display regions.

9. The method according to any one of claims 1-3, characterized by, the method further comprises: After the second ultrasonic echo data is acquired, a second tissue image is generated based on the second ultrasonic echo data, and the second tissue image is displayed in a first display area; The first super-resolution contrast image and the second tissue image are simultaneously displayed in a second display area, and the first super-resolution contrast image is displayed as a foreground image superimposed on the second tissue image, Wherein, the first display area and the second display area are different display areas.

10. The method of claim 9, wherein, The method further comprises: In the second display area, the first super-resolution contrast image is replaced by the second super-resolution contrast image, and the second super-resolution contrast image is displayed.

11. The method of claim 9, wherein, The method further comprises: The second super-resolution contrast image is displayed in a third display area, wherein the third display area and the second display area are different display areas, so that the second super-resolution contrast image and the first super-resolution contrast image can be simultaneously displayed without blocking each other.

12. The method according to any one of claims 1-3, characterized by, After the first super-resolution contrast image is displayed, the method further comprises: A region to be enlarged is determined on the first super-resolution contrast image, wherein the region to be enlarged is part or all of the super-resolution imaging region; The second data is obtained by processing the second ultrasonic echo data based on the second imaging parameter, and the second contrast agent microbubble recognition threshold is determined based on the second data, and the second super-resolution contrast image corresponding to part or all of the super-resolution imaging region is generated by processing the second data based on the second contrast agent microbubble recognition threshold, comprising: The second ultrasonic echo data of the region to be enlarged is acquired, the second data is obtained by processing the second ultrasonic echo data of the region to be enlarged based on the second imaging parameter, and the second contrast agent microbubble recognition threshold is determined based on the second data, and the second super-resolution contrast image corresponding to the region to be enlarged is generated by processing the second data based on the second contrast agent microbubble recognition threshold.

13. The method of claim 12, wherein, The method further comprises: An identifier of the region to be enlarged is displayed on the first super-resolution contrast image.

14. A super-resolution imaging method, characterized by, The method comprises: The ultrasonic probe is controlled to emit second ultrasonic waves to the target tissue injected with contrast agent at a first emission parameter, the echoes of the second ultrasonic waves are received, the first data is obtained by processing the second ultrasonic echo data, and the first contrast agent microbubble recognition threshold is determined based on the first data, and the first super-resolution contrast image is generated by processing the first data based on the first contrast agent microbubble recognition threshold; The first super-resolution contrast image is displayed; A region to be enlarged is determined on the first super-resolution contrast image; in response to the received user instruction to zoom in the first super-resolution contrast image, controlling the ultrasound probe to transmit third ultrasound waves to the target tissue injected with the contrast agent with a second transmission parameter, receiving echoes of the third ultrasound waves, processing the third ultrasound echo data to obtain third data, determining a third microbubble recognition threshold based on the third data, and processing the third data based on the third microbubble recognition threshold to generate a third super-resolution contrast image corresponding to the region to be zoomed in. displaying the third super-resolution contrast image.

15. The method of claim 14, wherein the second transmission parameter is different from the first transmission parameter, and the third super-resolution contrast image has a higher quality than the first super-resolution contrast image.

16. A display method of a super-resolution image, characterized by, the method comprises: displaying a first tissue image of the target tissue; selecting a super-resolution imaging region on the first tissue image; after the target tissue is injected with the contrast agent, displaying a first super-resolution contrast image corresponding to the super-resolution imaging region, the first super-resolution contrast image being generated with a first imaging parameter; in response to receiving a user instruction to zoom in the first super-resolution contrast image, displaying a second super-resolution contrast image corresponding to a region to be zoomed in on the first super-resolution contrast image, the second super-resolution contrast image being generated with a second imaging parameter, wherein at least one parameter in the second imaging parameter has a value greater than a value of a same parameter in the first imaging parameter, the second super-resolution contrast image has a size greater than a size of an image portion corresponding to the region to be zoomed in on the first super-resolution contrast image, and the second super-resolution contrast image has a resolution no less than a resolution of the image portion.

17. The method of claim 16, wherein, the method further comprises: presenting a user interaction interface, wherein the user interaction interface provides a selection control for a user to select a zoom-in factor and / or an input control for a user to input a zoom-in factor; receiving the user instruction based on the selection control and / or the input control.

18. The method of claim 16, wherein, the method further comprises: after the target tissue is injected with the contrast agent, displaying a first conventional contrast image; after displaying the first conventional contrast image, displaying the first super-resolution contrast image.

19. The method according to any one of claims 16-18, characterized by, the second super-resolution contrast image and the first super-resolution contrast image are displayed in different display regions.

20. The method of any one of claims 16-18, wherein after the target tissue is injected with the contrast agent, displaying a second tissue image in a first display region; simultaneously displaying the first super-resolution contrast image and the second tissue image in a second display region, and displaying the first super-resolution contrast image as a foreground image superimposed on the second tissue image, wherein the first display region and the second display region are different display regions.

21. The method of claim 20, wherein, the method further comprises: replacing the first super-resolution contrast image with the second super-resolution contrast image in the second display region and displaying the second super-resolution contrast image.

22. The method of claim 20, wherein, the method further comprises: displaying the second super-resolution angiogram image in a third display area, wherein the third display area is different from the second display area, so that the second super-resolution angiogram image and the first super-resolution angiogram image can be displayed simultaneously without blocking each other.

23. The method of any of claims 16-18, wherein, After displaying the first super-resolution angiogram image, the method further comprises: determining a region to be enlarged on the first super-resolution angiogram image, wherein the region to be enlarged is part or all of the super-resolution imaging region; displaying a second super-resolution angiogram image corresponding to the region to be enlarged.

24. The method of claim 23, wherein, The method further comprises: displaying an identifier of the region to be enlarged on the first super-resolution angiogram image.

25. An ultrasound imaging apparatus, characterized by The device comprises a transmitting and receiving circuit, an ultrasonic probe, a processor and a display, wherein: the transmitting and receiving circuit is configured to control the ultrasonic probe to emit ultrasonic waves to a target object, receive echoes of the ultrasonic waves, and obtain ultrasonic echo data from the echoes; the processor is configured to control the transmitting and receiving circuit, and execute the method of any one of claims 1-24 to generate a first tissue image, a first super-resolution angiogram image and a second super-resolution angiogram image; the display is configured to display the first tissue image, the first super-resolution angiogram image and the second super-resolution angiogram image.

Images