Traditional Chinese medicine face cleansing gel capable of rapidly resisting wrinkles and tightening skin and preparation method of traditional Chinese medicine face cleansing gel

Abstract

The invention provides a traditional Chinese medicine face cleansing gel capable of rapidly resisting wrinkles and tightening and a preparation method thereof, and belongs to the technical field of cosmetics, the traditional Chinese medicine face cleansing gel comprises the following raw material components by weight: 2-5% of disodium cocoamphodiacetate, 8-12% of decyl glucoside, 4-7% of a traditional Chinese medicine compound, 0.1-0.3% of cineole, 1-1.5% of polyquaternium-51, 0.3-0.6% of carnosine, 3-5% of glycerin, 1-2% of PEG-7 glyceryl cocoate, and the balance of water. The cleaning agent is prepared from the following components in percentage by weight: 0.3 to 0.5 percent of carbomer U20, 0.6 to 0.8 percent of preservative, 0.1 to 0.3 percent of sodium chloride, 0.3 to 0.8 percent of triethanolamine, 0.1 to 0.15 percent of essence and the balance of distilled water. The traditional Chinese medicine compound is a mixture of a centella asiatica alcohol extract, an astragalus membranaceus alcohol extract and a radix asparagi aqueous extract which are coated with lipidosome. According to the facial cleansing gel, the adsorption rate of the traditional Chinese medicine ingredients on the face is increased by adding the traditional Chinese medicine ingredients coated with the lipidosome into the facial cleansing gel, and meanwhile, the polyquaternium-51 forms a film and locks water after cleansing the face, so that the adhesion of the traditional Chinese medicine ingredients is synergistically enhanced, and the effects of quickly resisting wrinkles and immediately tightening the skin are achieved.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, specifically to a fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleanser and its preparation method. Background Technology

[0002] Skin aging includes endogenous aging and exogenous aging. Endogenous aging is mainly due to the functional decline of fibroblasts, the key cells that synthesize extracellular matrix such as collagen, elastin, and hyaluronic acid. Exogenous aging is mainly caused by damage from reactive oxygen free radicals generated by ultraviolet radiation. Therefore, anti-wrinkle products mostly focus on stimulating fibroblast regeneration, replenishing collagen, elastin, hyaluronic acid, and other substances, clearing free radicals generated by ultraviolet radiation, and are mostly leave-on products.

[0003] The contemporary society's emphasis on skin health and youthfulness has driven profound changes in the skincare market: the demand for anti-aging has shifted from traditional serums and creams to the initial step of the skincare routine—cleansing; consumers are no longer satisfied with the "repair after cleansing" model, but instead pursue an anti-aging strategy of "cleansing as defense".

[0004] Most existing facial cleansing formulas focus on cleansing. To effectively remove sebum, dirt, and makeup residue, many formulas rely heavily on pure petrochemical ingredients. Some of these ingredients can irritate the skin, causing sensitivity and other problems. Replacing some chemical ingredients with traditional Chinese medicine can soothe skin allergy symptoms. Furthermore, the antioxidants in traditional Chinese medicine can remove free radicals generated by UV exposure during cleansing, thus contributing to skin repair. However, the cleansing process involves rinsing with a large amount of water, and the herbal ingredients are easily washed away along with the water by the emulsifying and solubilizing effects of surfactants, making it difficult for them to effectively adhere to the skin's surface.

[0005] Therefore, increasing the adsorption of active ingredients in facial cleansers on the skin surface is a key aspect of the preparation process. Summary of the Invention

[0006] The purpose of this invention is to provide a fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleanser and its preparation method, so as to solve the problems mentioned in the background art.

[0007] To achieve the above objectives, the present invention provides the following technical solution:

[0008] A fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleansing gel, characterized in that, by weight percentage, it comprises the following raw material components: disodium cocoamphodiacetate 2-5%, decyl glucoside 8-12%, traditional Chinese medicine complex 4-7%, eucalyptol 0.1-0.3%, polyquaternium-51 1-1.5%, carnosine 0.3-0.6%, glycerin 3-5%, PEG-7 glyceryl cocoate 1-2%, carbomer U20 0.3-0.5%, preservative 0.6-0.8%, sodium chloride 0.1-0.3%, triethanolamine 0.3-0.8%, fragrance 0.1-0.15%, and the balance being distilled water. The traditional Chinese medicine complex is a mixture of liposome-coated Centella asiatica alcohol extract, Astragalus membranaceus alcohol extract, and Asparagus cochinchinensis water extract.

[0009] Specifically, the extraction methods for Centella asiatica alcohol extract include:

[0010] (1) After cleaning the Centella asiatica, dry it thoroughly and crush it. After crushing, add 70% ethanol at a material-to-liquid ratio of 1:15 (g:mL). Reflux and extract at 70-80℃ 2-3 times, 2 hours each time.

[0011] (2) Combine the extracts, filter them, concentrate them under reduced pressure until there is no alcohol odor, and spray dry to obtain Centella asiatica alcohol extract powder.

[0012] The extraction methods for Astragalus ethanol extract include:

[0013] (1) After cleaning the Astragalus membranaceus, dry it thoroughly and pulverize it. After pulverizing, add 70% ethanol at a material-to-liquid ratio of 1:15 (g:mL) and reflux extract at 70-80℃ for 2-3 times, 2 hours each time.

[0014] (2) Combine the extracts, filter them, concentrate them under reduced pressure until there is no alcohol odor, and spray dry to obtain Astragalus alcohol extract powder.

[0015] The extraction methods for asparagus water extracts include:

[0016] (1) After cleaning the tuberous roots of Asparagus, dry them and crush them. After crushing, add distilled water at a ratio of 1:10 (g:mL) and boil them 2-3 times, 1 hour each time.

[0017] (2) Combine the extracts, filter them, concentrate them under reduced pressure, and spray dry them to obtain asparagus water extract powder.

[0018] Preferably, the preservative is a mixture of phenoxyethanol and ethylhexylglycerin in a mass ratio of 1.5:1.

[0019] Preferably, the preparation of the traditional Chinese medicine compound includes the following steps:

[0020] S1. Lipid membrane formation: Egg yolk lecithin and cholesterol were added to anhydrous ether, dissolved by sonication, and then transferred to a round-bottom flask. Centella asiatica extract and Astragalus membranaceus extract were added to anhydrous ethanol, dissolved by sonication, and then added to the round-bottom flask. The mixture was shaken evenly, and the organic solvent was removed by vacuum distillation in a water bath at 40°C to form a uniform lipid membrane on the round-bottom flask.

[0021] S2. Hydration and drug loading: Add the asparagus water extract to phosphate buffer, sonicate to dissolve, and then add it to the round bottom flask of step S1. Sonicate until hydration is complete to form a multilayer liposome suspension A.

[0022] S3. Nanoparticle formation: Liposome suspension A is processed by a high-pressure homogenizer to obtain a monolayer liposome suspension B;

[0023] S4. Sterilization and preservation: Pass the liposome suspension B through a 0.22μm filter membrane to obtain the traditional Chinese medicine complex, and store it at 4℃ in the dark.

[0024] Preferably, in step S2, the mass ratio of egg yolk lecithin: cholesterol: Centella asiatica alcohol extract: Astragalus membranaceus alcohol extract: Asparagus cochinchinensis water extract in suspension A is 5:1:(0.6-0.9):(0.4-0.6):(0.2-0.3).

[0025] Preferably, in step S2, the phosphate buffer concentration is 0.05 mol / L, the pH is 7.0, the hydration temperature is 55°C, and the hydration time is 30–40 min.

[0026] Preferably, in step S3, the particle size of the liposome suspension B is 90–120 nm.

[0027] This invention also discloses a method for preparing a fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleanser, comprising the following steps:

[0028] A1. After cleaning and disinfecting the emulsifying pot, add disodium cocoamphodiacetate, decyl glucoside, eucalyptol, carnosine, glycerin, PEG-7 glyceryl cocoate, carbomer U20, preservative, sodium chloride, flavoring and most of the distilled water, and stir until the mixture is semi-transparent.

[0029] A2. Add the traditional Chinese medicine complex, polyquaternium-51 and the remaining water, and stir at low speed for 5 to 10 minutes;

[0030] A3. Add triethanolamine to adjust the pH of the seasoning mixture to 5.5–6.0;

[0031] A4. Let stand to defoam, and the finished product is obtained.

[0032] The beneficial effects of the above-described technical solution of the present invention are as follows:

[0033] 1. This invention uses traditional Chinese medicine ingredients as antioxidants. Centella asiatica contains asiaticoside, asiaticoside, and asiatic acid, etc. Aceticoside has antioxidant and immunomodulatory effects, asiaticoside can promote skin growth, and asiatic acid has anti-inflammatory, antibacterial, and anti-aging effects. Astragalus is rich in saponins (such as astragaloside A), flavonoids, and polysaccharides, etc. Asparagus also contains polysaccharides. Astragaloside A can delay cell aging, flavonoids have antioxidant effects and can scavenge free radicals, and polysaccharides have various biological activities such as lowering blood sugar, anti-oxidation, anti-tumor, and improving immunity. By using traditional Chinese medicine ingredients instead of chemical ingredients, the side effects of chemical ingredients, such as skin allergies, are avoided, which is more in line with the development trend of "green health".

[0034] 2. Liposomes, as microcapsule structures composed of phospholipid bilayers, have cell membrane-like properties and can simultaneously encapsulate water-soluble and lipid-soluble substances. The biomembrane-like structure of liposomes has a strong affinity for the stratum corneum of the skin, and encapsulating traditional Chinese medicine can increase the adsorption of traditional Chinese medicine components on the skin.

[0035] 3. Polyquaternium-51 is a positively charged cationic polymer. Since the surface of human skin is usually slightly negatively charged at physiological pH, this positively charged polymer can generate a stronger affinity with the skin through electrostatic attraction, increasing its adsorption rate during rinsing. Furthermore, polyquaternium-51 is an excellent film-forming agent. When diluted in an aqueous system (e.g., by adding water and rubbing during cleansing), it tends to precipitate from the solution and deposit on the skin surface, forming a thin film that resists rinsing. Therefore, its film-forming properties can be used to "anchor" the entire herbal complex to the skin surface, thereby increasing the adsorption of herbal components. In addition, polyquaternium-51 itself has excellent moisturizing properties, which can be maintained even after washing. The water-locking film it forms can quickly replenish and lock in moisture in the stratum corneum, making dry keratinocytes plump and thus visually reducing fine lines caused by dryness.

[0036] 4. This invention uses decyl glucoside as a surfactant to replace the traditional sodium lauroyl sarcosinate, resulting in less foam and easier defoaming, which can reduce rinsing time and thus reduce the loss of anti-wrinkle ingredients; in addition, decyl glucoside has lower skin irritation and is gentler.

[0037] 5. Eucalyptol, as a lipophilic small molecule, can penetrate the lipid region of the stratum corneum, interfere with lipid arrangement, increase the fluidity of intercellular spaces, thereby forming temporary channels and promoting penetration.

[0038] In summary, this solution utilizes eucalyptus oil for enhanced penetration, liposome encapsulation of traditional Chinese medicine to increase adsorption, and polyquaternium-51 to further enhance adsorption and form a film for water retention. Combined with a low-foaming system, it comprehensively improves the adsorption rate of traditional Chinese medicine ingredients in the facial cleansing gel on the face, effectively removes free radicals from the skin surface, and provides immediate hydration, resulting in a rapid anti-wrinkle effect. Detailed Implementation

[0039] The preferred embodiments of the present invention are described below. It should be understood that the preferred embodiments described herein are for illustration and explanation only and are not intended to limit the present invention.

[0040] For experiments not specified in this protocol, the procedures and conditions described in the literature in this field should be followed. Reagents or instruments whose manufacturers are not specified are all commercially available products.

[0041] Example

[0042] A fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleansing gel, by weight percentage, comprises the following raw material components: disodium cocoamphodiacetate 2-5%, decyl glucoside 8-12%, traditional Chinese medicine complex 4-7%, eucalyptol 0.1-0.3%, polyquaternium-51 1-1.5%, carnosine 0.3-0.6%, glycerin 3-5%, PEG-7 glyceryl cocoate 1-2%, carbomer U20 0.3-0.5%, preservative 0.6-0.8%, sodium chloride 0.1-0.3%, triethanolamine 0.3-0.8%, fragrance 0.1-0.15%, and the balance being distilled water.

[0043] The herbal compound is a mixture of liposome-coated Centella asiatica alcohol extract, Astragalus membranaceus alcohol extract, and Asparagus cochinchinensis water extract; the preservative is a mixture of phenoxyethanol and ethylhexylglycerin in a mass ratio of 1.5:1.

[0044] Specifically, the preparation of the traditional Chinese medicine complex includes the following steps:

[0045] S1. Lipid membrane formation: 25 mg egg yolk lecithin and 5 mg cholesterol were added to 5 mL of anhydrous ether, dissolved by sonication, and then transferred to a round-bottom flask. 3–4.5 mg of Centella asiatica extract and 2–3 mg of Astragalus membranaceus extract were added to 3 mL of anhydrous ethanol, dissolved by sonication, and then added to the round-bottom flask. The mixture was shaken evenly, and the organic solvent was removed by vacuum distillation in a 40°C water bath to form a uniform lipid membrane on the round-bottom flask.

[0046] S2. Hydration and drug loading: Add 1-1.5 mg of asparagus water extract to 6 mL of 0.05 mol / L pH 7.0 phosphate buffer, sonicate to dissolve, and then add to the round-bottom flask of step S1. Sonicate at 55℃ for 30-40 min to form a multilayer liposome suspension A.

[0047] S3. Nanoparticles: Liposome suspension A is processed by a high-pressure homogenizer to obtain a monolayer liposome suspension B with a particle size of 90-120 nm.

[0048] S4. Sterilization and preservation: Pass the liposome suspension B through a 0.22μm filter membrane to obtain the traditional Chinese medicine complex, and store it at 4℃ in the dark.

[0049] A method for preparing a fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleanser includes the following steps:

[0050] A1. After cleaning and disinfecting the emulsifying pot, add disodium cocoamphodiacetate, decyl glucoside, eucalyptol, carnosine, glycerin, PEG-7 glyceryl cocoate, carbomer U20, preservative, sodium chloride, flavoring and most of the distilled water, and stir until the mixture is semi-transparent.

[0051] A2. Add the traditional Chinese medicine complex, polyquaternium-51 and the remaining water, and stir at low speed for 5 to 10 minutes;

[0052] A3. Add triethanolamine to adjust the pH of the seasoning mixture to 5.5–6.0;

[0053] A4. Let stand to defoam, and the finished product is obtained.

[0054] Example 1

[0055] The preparation method of the rapid anti-wrinkle and firming traditional Chinese medicine facial cleanser described in the above embodiments includes the following components by weight percentage:

[0056] Disodium cocoamphodiacetate 4%, decyl glucoside 10%, traditional Chinese medicine complex 6%, eucalyptol 0.2%, polyquaternium-51 1.2%, carnosine 0.5%, glycerol 4%, PEG-7 glyceryl cocoate 1.5%, carbomer U20 0.4%, preservative 0.7%, sodium chloride 0.2%, triethanolamine 0.5%, fragrance 0.12%, balance distilled water.

[0057] In step S2 of the preparation of the traditional Chinese medicine complex, the mass ratio of egg yolk lecithin: cholesterol: Centella asiatica alcohol extract: Astragalus membranaceus alcohol extract: Asparagus cochinchinensis water extract in suspension A is 5:1:0.75:0.5:0.25.

[0058] Example 2

[0059] The preparation method of the rapid anti-wrinkle and firming traditional Chinese medicine facial cleanser described in the above embodiments includes the following components by weight percentage:

[0060] Disodium cocoamphodiacetate 2%, decyl glucoside 12%, traditional Chinese medicine complex 4%, eucalyptol 0.1%, polyquaternium-51 1.5%, carnosine 0.3%, glycerol 3%, PEG-7 glyceryl cocoate 1%, carbomer U20 0.3%, preservative 0.6%, sodium chloride 0.1%, triethanolamine 0.3%, fragrance 0.1%, balance distilled water.

[0061] In step S2 of the preparation of the traditional Chinese medicine complex, the mass ratio of egg yolk lecithin: cholesterol: Centella asiatica alcohol extract: Astragalus membranaceus alcohol extract: Asparagus cochinchinensis water extract in suspension A is 5:1:0.9:0.4:0.2.

[0062] Example 3

[0063] The preparation method of the rapid anti-wrinkle and firming traditional Chinese medicine facial cleanser described in the above embodiments includes the following components by weight percentage:

[0064] Disodium cocoamphodiacetate 5%, decyl glucoside 8%, traditional Chinese medicine complex 7%, eucalyptol 0.3%, polyquaternium-51 1%, carnosine 0.6%, glycerol 5%, PEG-7 glyceryl cocoate 2%, carbomer U20 0.5%, preservative 0.8%, sodium chloride 0.3%, triethanolamine 0.8%, fragrance 0.15%, balance distilled water.

[0065] In step S2 of the preparation of the traditional Chinese medicine complex, the mass ratio of egg yolk lecithin: cholesterol: Centella asiatica alcohol extract: Astragalus membranaceus alcohol extract: Asparagus cochinchinensis water extract in suspension A is 5:1:0.6:0.6:0.3.

[0066] Comparative Example 1

[0067] The difference between this and Example 1 is that it does not use liposomes to encapsulate the herbal extract, and by weight percentage includes the following components:

[0068] Disodium cocoamphodiacetate 4%, decyl glucoside 10%, Centella asiatica extract 4.5%, Astragalus membranaceus extract 3%, Asparagus cochinchinensis extract 1.5%, eucalyptol 0.2%, polyquaternium-51 1.2%, carnosine 0.5%, glycerol 4%, PEG-7 glyceryl cocoate 1.5%, carbomer U20 0.4%, preservative 0.7%, sodium chloride 0.2%, triethanolamine 0.5%, fragrance 0.12%, balance distilled water.

[0069] Comparative Example 2

[0070] The difference between this example and Example 1 is that polyquaternium-51 is not added.

[0071] Comparative Example 3

[0072] The difference between this and Example 1 is that no traditional Chinese medicine compound is added.

[0073] Comparative Example 4

[0074] The difference between this and Example 1 is that eucalyptol is not added.

[0075] Comparative Example 5

[0076] The difference between this and Example 1 is that sodium lauroyl sarcosinate is used instead of decyl glucoside.

[0077] Experiment 1: Stability Evaluation

[0078] The facial cleansing gel prepared in Example 1 was divided into three groups. Two groups were placed at 25 and 40°C for 28 days, and the other group was placed at -20°C for 10 days. After that, the product was warmed to room temperature, and the appearance and pH value changes were observed visually. The results are shown in Table 1.

[0079] Table 1. Stability test results

[0080] Group Appearance pH 25℃ Transparent and uniform, without layering 5.78 40℃ Transparent and uniform, without layering 5.57 -20℃ Transparent and uniform, without layering 5.91

[0081] As shown in Table 1, the facial cleansing gel prepared in Example 1 was transparent, did not separate into layers, and was stable after being placed at 25 and 40°C for 28 days and at -20°C for 10 days and then allowed to warm to room temperature.

[0082] Experiment 2: Evaluation of antioxidant properties

[0083] Prepare a 0.04 mg / mL DPPH (1,1-diphenyl-2-trinitrophenylhydrazine) solution (solvent: anhydrous ethanol). Take 100 mg of facial cleansing gel and add 10 mL of anhydrous ethanol. Sonicate for 10 min and centrifuge to collect the supernatant. Take a 96-well plate, add 100 μL of DPPH solution, and then add 100 μL of gel supernatant. Mix well and react at room temperature in the dark for 30 min. Measure the absorbance value A1 at 517 nm. Measure the absorbance value A0 with anhydrous ethanol and DPPH, and measure the absorbance value A2 with anhydrous ethanol and gel supernatant.

[0084]

[0085] In the formula, A1 is the absorbance value measured by mixing DPPH solution with gel supernatant; A2 is the absorbance value obtained by mixing gel supernatant with anhydrous ethanol (blank group); and A0 is the absorbance value obtained by mixing DPPH solution with anhydrous ethanol (control group).

[0086] Table 2 Results of Antioxidant Test

[0087] Group Antioxidant activity / % Example 1 19.8 Example 2 19.1 Example 3 19.6 Comparative Example 3 0.9

[0088] DPPH has a characteristic absorption at 517 nm. Antioxidants can scavenge DPPH free radicals, resulting in a decrease in absorbance. The scavenging rate can be calculated by measuring the change in absorbance using an enzyme-linked immunosorbent assay (ELISA) reader. As shown in Table 1, the traditional Chinese medicine complex in the formula has the ability to scavenge free radicals and possesses antioxidant properties.

[0089] Experiment 3: Measuring the adsorption rate of traditional Chinese medicine components on the skin surface

[0090] Clean the inner forearm (5×5cm area) of the subject, rinse with water and air dry. Peel off the adhesive tape 3 times, each time for 10 seconds, and collect the sample as the baseline sample. Apply 0.5g of facial cleansing gel to the experimental area, massage gently for 1 minute, rinse thoroughly with water at a constant flow rate (no foam and no stickiness), and air dry naturally. After air drying, peel off the adhesive tape 3 times, each time for 10 seconds, and collect the experimental sample. Dissolve the sample in methanol and extract by ultrasonication for 30 minutes. Quantitatively analyze the adsorption rate of asiatic acid on the skin surface by high performance liquid chromatography. The results are shown in Table 3.

[0091] Table 3. Adsorption rate of asiatic acid on skin surface after cleansing

[0092] Group Adsorption rate / % Example 1 19.2 Example 2 18.6 Example 3 18.8 Comparative Example 1 5.1 Comparative Example 2 4.7 Comparative Example 4 13.1 Comparative Example 5 7.3

[0093] Note: Adsorption rate = Adsorption amount on skin surface / Initial content × 100%.

[0094] Except for Comparative Example 5, the cleansing gels in the other groups could be washed off in 10 seconds, while Comparative Example 5 required 20 seconds to be washed off. Therefore, the adsorption rate of asiatic acid on the skin surface was lower than that in Example 1. The results of Comparative Examples 1 and 2 show that liposome encapsulation and the addition of polyquaternium-51 can significantly increase the adsorption rate of active ingredients on the skin surface. Comparative Example 4 shows that the diffusion effect of eucalyptol can promote the adsorption of liposome-encapsulated active ingredients on the skin surface.

[0095] Experiment 4: Skin Moisture and Skin Elasticity Test

[0096] 160 healthy female subjects aged 30-40 years were selected for the test and divided into 8 groups of 20 people each. After cleansing their faces with the facial cleansing gel products of Examples 1-3 and Comparative Examples 1-5, the subjects patted their skin dry with a tissue and were tested in an environment with a temperature of 25°C and a humidity of about 50%. The subjects' skin moisture and skin elasticity were tested.

[0097] The skin moisture content of the subjects was measured and recorded on both cheekbones before and 30 minutes after cleansing using a Corneometer CM 825 skin moisture meter. The average of the three measurements was taken as the final result, as shown in Table 4.

[0098] Table 4. Skin Moisture Test Results

[0099] Group Clean face After cleansing Improvement rate / % Example 1 35.2 44.3 25.85 Example 2 37.7 46.9 24.40 Example 3 36.6 45.8 25.14 Comparative Example 1 31.7 36.8 16.09 Comparative Example 2 38.9 43.1 10.80 Comparative Example 3 37.6 43.2 14.89 Comparative Example 4 35.0 42.9 22.57 Comparative Example 5 36.2 43.4 19.89

[0100] The skin elasticity of the subjects was measured and recorded on both cheekbones before and 30 minutes after cleansing using a Cutometer MPA580 skin elasticity tester. The average R2 value of the three measurements was taken as the final result, as shown in Table 5. Wherein, R2 = Ua / Uf; Ua is the skin recovery value when negative pressure is removed and then applied again in the next continuous test; Uf is the maximum stretch of the skin when negative pressure is applied (the closer R2 is to 1, the better the elasticity).

[0101] Table 5 Results of Skin Elasticity Test

[0102]

[0103]

[0104] By comparing the data of Examples 1-3 with Comparative Examples 1-5 in Tables 4 and 5, it can be seen that the product containing both the traditional Chinese medicine complex and polyquaternium-51 has a better effect on improving skin moisture content and skin elasticity.

[0105] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Any other modifications or equivalent substitutions made by those skilled in the art to the technical solutions of the present invention, as long as they do not depart from the spirit and scope of the technical solutions of the present invention, should be covered within the scope of the claims of the present invention.

Claims

1. A fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleanser, characterized in that, The product comprises, by weight percentage, the following raw material components: disodium cocoamphodiacetate 2-5%, decyl glucoside 8-12%, traditional Chinese medicine complex 4-7%, eucalyptol 0.1-0.3%, polyquaternium-511-1.5%, carnosine 0.3-0.6%, glycerol 3-5%, PEG-7 glyceryl cocoate 1-2%, carbomer U20 0.3-0.5%, preservative 0.6-0.8%, sodium chloride 0.1-0.3%, triethanolamine 0.3-0.8%, fragrance 0.1-0.15%, and the balance being distilled water. The traditional Chinese medicine complex is a mixture of liposome-coated Centella asiatica alcohol extract, Astragalus membranaceus alcohol extract, and Asparagus cochinchinensis water extract.

2. The fast-acting anti-wrinkle and firming herbal facial cleanser according to claim 1, characterized in that, The preservative is a mixture of phenoxyethanol and ethylhexylglycerin in a mass ratio of 1.5:

1.

3. The fast-acting anti-wrinkle and firming herbal facial cleanser according to claim 1, characterized in that, The preparation of traditional Chinese medicine complexes includes the following steps: S1. Lipid membrane formation: Egg yolk lecithin and cholesterol were added to anhydrous ether, dissolved by sonication, and then transferred to a round-bottom flask. Centella asiatica extract and Astragalus membranaceus extract were added to anhydrous ethanol, dissolved by sonication, and then added to the round-bottom flask. The mixture was shaken evenly, and the organic solvent was removed by vacuum distillation in a water bath at 40°C to form a uniform lipid membrane on the round-bottom flask. S2. Hydration and drug loading: Add the asparagus water extract to phosphate buffer, sonicate to dissolve, and then add it to the round bottom flask of step S1. Sonicate until hydration is complete to form a multilayer liposome suspension A. S3. Nanoparticles: Liposome suspension A is processed by a high-pressure homogenizer to obtain a monolayer liposome suspension B; S4. Sterilization and preservation: Pass the liposome suspension B through a 0.22μm filter membrane to obtain the traditional Chinese medicine complex, and store it at 4℃ in the dark.

4. The fast-acting anti-wrinkle and firming herbal facial cleanser according to claim 3, characterized in that, In step S2, the mass ratio of egg yolk lecithin: cholesterol: Centella asiatica alcohol extract: Astragalus membranaceus alcohol extract: Asparagus cochinchinensis water extract in suspension A is 5:1:(0.6-0.9):(0.4-0.6):(0.2-0.3).

5. The fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleanser according to claim 3, characterized in that, In step S2, the hydration temperature is 55℃ and the hydration time is 30-40 minutes.

6. The fast-acting anti-wrinkle and firming herbal facial cleansing gel according to claim 3, characterized in that, In step S3, the particle size of liposome suspension B is 90–120 nm.

7. A method for preparing a fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleanser, comprising the fast-acting anti-wrinkle and firming traditional Chinese medicine facial cleanser according to any one of claims 1 to 6, characterized in that, Includes the following steps: A1. After cleaning and disinfecting the emulsifying pot, add disodium cocoamphodiacetate, decyl glucoside, eucalyptol, carnosine, glycerin, PEG-7 glyceryl cocoate, carbomer U20, preservative, sodium chloride, flavoring and most of the distilled water, and stir until the mixture is semi-transparent. A2. Add the traditional Chinese medicine complex, polyquaternium-51 and the remaining water, and stir at low speed for 5 to 10 minutes; A3. Add triethanolamine to adjust the pH of the seasoning mixture to 5.5–6.0; A4. Let stand to defoam, and the finished product is obtained.

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