Bionic wrist pulse generator

Abstract

The invention discloses a bionic wrist pulse generator, and relates to the technical field of medical instruments, the bionic wrist pulse generator comprises a wrist bionic structure and a blood vessel bionic structure, the wrist bionic structure comprises a bionic skin layer, a mounting layer and a supporting layer, and the mounting layer is arranged between the bionic skin layer and the supporting layer; when the device is used, the peristaltic pump draws liquid from the liquid groove and outputs the liquid into the elastic tube, the purpose of simulating pulse vibration signals of the wrist of the human body is achieved by adjusting parameters of the peristaltic pump, adjusting the flow of the liquid in the elastic tube and reproducing periodic signals, the three-stage branch network structure is designed, the first-stage branch simulates the arteriole, and the second-stage branch simulates the arteriole; the second-stage branch and the third-stage branch simulate a micro artery and a blood capillary respectively, and then a periodic signal is sensed on the bionic skin layer, so that the practice effect is achieved.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a bionic wrist pulse generator. Background Technology

[0002] Traditional Chinese medicine pulse diagnosis, as a core diagnostic method in traditional medicine, has irreplaceable value in clinical practice. However, its reliance on human experience in diagnosis faces practical difficulties such as long training cycles, low standardization, and limited large-scale promotion, urgently requiring technological innovation to overcome these development bottlenecks.

[0003] In the context of a healthcare environment where public health is increasingly being prioritized, traditional Chinese medicine pulse diagnosis, a testing method that relies on accumulated experience, will undoubtedly face numerous limitations.

[0004] Therefore, a bionic wrist pulse generator is needed for scholars to practice with. Summary of the Invention

[0005] To address the problems existing in the prior art, the present invention solves this problem using the following technical structure.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] A bionic wrist pulse generator includes: a wrist bionic structure and a blood vessel bionic structure. The wrist bionic structure includes a bionic skin layer, an mounting layer, and a support layer. The mounting layer is disposed between the bionic skin layer and the support layer.

[0008] The biomimetic vascular structure includes an elastic tube, a peristaltic pump, and a liquid tank. One end of the elastic tube is disposed in the mounting layer, and the other end is connected to the peristaltic pump. The peristaltic pump is connected to the liquid tank.

[0009] The biomimetic vascular structure also includes vascular branches and an injection pump. The vascular branches are disposed within the mounting layer, and the injection pump is connected to the vascular branches.

[0010] The vascular branch is a multi-level branching network structure, which includes at least a number of primary branch vessels, a number of secondary branch vessels, and a number of tertiary branch vessels, with the inner diameter of the primary branch vessels, secondary branch vessels, and tertiary branch vessels decreasing sequentially.

[0011] The elastic tube is disposed on the side of the vascular branch near the support layer.

[0012] The mounting layer is provided with multiple sets of piezoelectric ceramic sheets, which are arranged sequentially along the extension direction of the elastic tube. Each set of piezoelectric ceramic sheets includes two piezoelectric ceramic sheets, and the two piezoelectric ceramic sheets in the same set are arranged opposite each other on the circumferential outer side of the elastic tube.

[0013] The biomimetic skin layer is made of Ecoflex material.

[0014] The mounting layer is made of PDMS material.

[0015] The support layer includes a foamed silicone layer and a rigid support layer, wherein the foamed silicone layer is disposed between the mounting layer and the rigid support layer.

[0016] One end of the elastic tube is embedded in the mounting layer.

[0017] The vascular branch is embedded within the mounting layer.

[0018] The following beneficial effects can be achieved by using the structure described above in this invention:

[0019] In use, the peristaltic pump draws liquid from the liquid tank and outputs it to the elastic tube. By adjusting the parameters of the peristaltic pump, the flow rate of the liquid in the elastic tube is adjusted to reproduce the periodic signal, thereby mimicking the pulse vibration signal of the human wrist. Then, by sensing the periodic signal on the bionic skin layer, the practical effect is achieved.

[0020] By designing a three-level branch network structure, the first-level branches simulate small arteries, while the second-level and third-level branches simulate microarteries and capillaries, respectively. Attached Figure Description

[0021] Figure 1 This is a three-dimensional structural diagram of this embodiment;

[0022] Figure 2 This is a schematic diagram of the vascular branch structure in this embodiment.

[0023] In the diagram: 1. Bionic skin layer; 2. Installation layer; 3. Elastic tube; 4. Peristaltic pump; 5. Liquid tank; 6. Blood vessel branch; 61. Primary branch blood vessel; 62. Secondary branch blood vessel; 63. Tertiary branch blood vessel; 7. Injection pump; 8. Piezoelectric ceramic sheet; 9. Foamed silicone layer; 10. Rigid support layer. Detailed Implementation

[0024] To enable those skilled in the art to better understand the present invention, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of the present invention.

[0025] It should be noted that the terms "comprising" and "having" and any variations thereof in the specification, claims and accompanying drawings of this invention are intended to cover non-exclusive inclusion. For example, a process, method, apparatus, product or device that includes a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such process, method, product or device.

[0026] The following is in conjunction with the appendix Figures 1-2 This application will be described in further detail.

[0027] refer to Figures 1-2 The bionic wrist pulse generator shown includes: a wrist bionic structure and a blood vessel bionic structure. The wrist bionic structure includes a bionic skin layer 1, an mounting layer 2, and a support layer. The mounting layer 2 is disposed between the bionic skin layer 1 and the support layer. The support layer includes a thermally conductive silicone layer (for wrist heat conduction), a foamed silicone layer 9 (low-density foamed silicone), and a rigid support layer 10. The thermally conductive silicone layer is disposed between the foamed silicone layer 9 and the mounting layer 2, and the foamed silicone layer 9 is disposed between the thermally conductive silicone layer and the rigid support layer 10.

[0028] The biomimetic vascular structure includes an elastic tube 3 (flexible silicone tube), a peristaltic pump 4 (preferably BT100-3J model, with a pump head using a YZ1515X three-roller structure; the peristaltic pump 4 rotates along a fixed trajectory via a drive wheel set, sequentially squeezing the tubing in a periodic mechanical motion to achieve liquid transport), and a liquid tank 5. One end of the elastic tube 3 is located within the mounting layer 2, and the other end is connected to the peristaltic pump 4, which is connected to the liquid tank 5.

[0029] Based on the above structure, during use, the peristaltic pump draws liquid from the liquid tank 5 and outputs it to the elastic tube 3. By adjusting the parameters of the peristaltic pump, the flow rate of the liquid in the elastic tube 3 is adjusted to reproduce the periodic signal, thereby achieving the purpose of mimicking the pulse vibration signal of the human wrist. Then, by sensing the periodic signal on the bionic skin layer 1, the practical effect is achieved.

[0030] like Figure 1 and Figure 2As shown, the biomimetic vascular structure also includes vascular branches 6 and an infusion pump 7 (the infusion pump model can be LSP11-1AP). The vascular branch 6 is disposed within the mounting layer 2, and the elastic tube 3 is disposed on the side of the vascular branch 6 near the support layer. The infusion pump 7 is connected to the vascular branch 6 and includes a stepper motor drive module, a screw transmission mechanism, and a piston-type liquid storage chamber. It is sealed to the vascular branch 6 through a medical-grade silicone tubing (inner diameter 0.8mm, wall thickness 0.2mm). The vascular branch 6 is a multi-level branch network structure, which includes at least several primary branch vessels 61, several secondary branch vessels 62, and several tertiary branch vessels 63. The inner diameters of the primary branch vessels 61, secondary branch vessels 62, and tertiary branch vessels 63 decrease sequentially. Specifically, the tertiary branches can be fabricated using a microfluidic chip (the microfluidic chip uses polydimethylsiloxane (PDMS) material) and a soft photolithography process. The network structure (a three-level branched network structure is used in this embodiment) is as follows: the first-level branch (0.8 mm inner diameter) simulates arterioles, the second-level branch (0.3 mm inner diameter) and the third-level branch (200 μm inner diameter) simulate microarteries and capillaries, respectively. A 0.2 mm radius arc transition zone is set at the branch point to reduce fluid separation noise. The first-level branch vessel 61 is connected to the injection pump. The advantage of this design is that when the simulated blood flows through the branch network via the injection pump, the abrupt change in the cross-sectional area of ​​the third-level branch (area ratio 1:0.6:0.3:0.1) and the difference in wall elasticity induce turbulent noise and wall vibration noise of 50-500 Hz. The power spectral density of the simulated noise signal is expected to have a greater than 90% match with the physiological noise of human capillaries. Optionally, an extracellular matrix (ECM) protein with a thickness of 0.1 μm is coated on the inner wall of the third-level branch to further enhance the biomimicry of the noise signal.

[0031] like Figure 1As shown, to address the simulation of the three positions (cun, guan, and chi) in traditional Chinese medicine pulse diagnosis, multiple sets of piezoelectric ceramic sheets (three sets in this embodiment) are arranged within the mounting layer 2. These sets are sequentially arranged along the extension direction of the elastic tube 3. Each set includes two piezoelectric ceramic sheets 8, which are positioned opposite each other on the outer circumferential side of the elastic tube 3 (the piezoelectric ceramic sheets 8 clamp the elastic tube 3, and the clamping force is adjusted to achieve precise control of the vibration signal). An array of three sets of piezoelectric ceramic sheets is used to construct a distributed high-frequency pulse simulation system. The piezoelectric ceramic sheet layout strictly follows the positioning of the three pulse points (cun, guan, chi) in Traditional Chinese Medicine. Specifically, this can be achieved through a programmable circuit module. This module connects the three piezoelectric ceramic sheets to the circuit input port via a silver conductor layer (20μm thick, 0.5mm wide, resistivity 1.6×10⁻⁸Ω□m) embedded within mounting layer 2, thus achieving electrical connection. The core control of the circuit module is a microcontroller chip (MCU). In this invention, an STM32F407VGT6 MCU can be used, which integrates a 12-bit analog-to-digital converter (2.4MSPS sampling rate) and a digital-to-analog converter (0.8mV resolution). The MCU communicates with the high-voltage drive circuit via an SPI interface (10MHz speed) and simultaneously outputs six independent control signals to differentially drive the piezoelectric ceramic sheets. The control program stored in the MCU's Flash memory achieves the following functions:

[0032] The waveform generation function supports preset high-frequency characteristic components of dozens of standard pulse waveforms (such as string pulse, slippery pulse, fine pulse, etc.), and the frequency range, amplitude range and phase difference of the control piezoelectric ceramic sheet are adjustable to achieve multi-parameter simulation.

[0033] The dynamic parameter modulation function receives custom parameters (such as frequency, amplitude, and phase difference) sent by the host computer via USB interface, and updates the control parameters after CRC32 verification. It supports two modulation modes: synchronous modulation: the three piezoelectric ceramic plates vibrate with the same waveform parameters for basic pulse simulation; asynchronous modulation: each part is controlled independently to realize differentiated pulse characteristics of the three parts and nine pulse positions (such as the combination of floating pulse in the cun position, wiry pulse in the guan position, and deep pulse in the chi position).

[0034] The biomimetic skin layer 1 can be made of Ecoflex (Ecoflex is a biodegradable polymer commonly used in various industries. It is composed of two main components, polylactic acid (PLA) and poly(hexamethylene terephthalate) succinate (PBAT). During the fabrication of the Ecoflex layer, its diffuse reflection capability is artificially controlled by adjusting the concentration of internal nanoparticles, and reflection parameters are specifically designed for different locations. Furthermore, surface textures are etched onto the upper surface of the Ecoflex layer using techniques such as soft lithography, thereby simulating the scattering characteristics caused by the roughness of human epidermis. This designed Ecoflex layer can significantly improve the optical detection adaptability of equipment and solve the problems of "oversaturation" or "under-distortion" of laser signals on traditional smooth elastomer surfaces.

[0035] Mounting layer 2 is made of PDMS (PDMS is a type of elastic organosilicon polymer), and one end of the elastic tube 3 and the blood vessel branch 6 are embedded in mounting layer 2.

[0036] like Figure 1 As shown, below the mounting layer 2 (PDMS layer), low-density foamed silicone is used as a buffer layer, and a composite structure design of rigid support layer and low-density foamed silicone layer is used. The rigid support layer, as a biomimetic structure constraining the wrist bones, is used to fix the position of the signal generator, resist structural displacement caused by various vibration signals from the wrist, and provide a stable bearing platform for the upper biomimetic skin layer 1 (Ecoflex layer), microcontroller chip, and piezoelectric ceramic sheet, preventing structural deformation due to external pressure or internal driven vibration, ensuring the stability of the vibration transmission path of the biomimetic blood vessel (such as elastic tube 3), maintaining the accuracy of pulse simulation, and providing a stable optical detection interface. The low-density foamed silicone layer is used to simulate the buffering effect of dermal elasticity and subcutaneous fat, reducing the impact of pulse vibration on the overall state of the instrument and dissipating the vibration transmitted downwards from the middle PDMS layer.

[0037] In summary, the wrist bionic structure adopts a layered design to simulate human skin, vascular network and wrist bones, taking into account both flexible fit and rigid support, adapting to wearable devices and desktop experimental platforms, and improving environmental compatibility.

[0038] Layered biomimetic support design: The upper Ecoflex layer simulates skin reflection and scattering, the middle PDMS layer generates vascular signals, and the lower composite structure (thermal conductive silicone + foamed silicone + rigid layer) achieves thermal management and noise isolation;

[0039] It has the ability to simulate pathological signals (peristaltic pump and injection pump work together to reproduce periodic signals and adapt to pathological noise simulation (such as arteriosclerosis)): It supports modulus differentiation adjustment under pathological conditions such as arteriosclerosis, and combined with dynamic parameter modulation, it provides a reliable model for pulse diagnosis of complex diseases.

[0040] The above are merely preferred embodiments of this application, and the present invention is not limited to the above embodiments. It is understood that other improvements and variations that are directly derived or conceived by those skilled in the art without departing from the spirit and concept of the present invention should be considered to be included within the protection scope of the present invention.

Claims

1. A bionic wrist pulse generator, characterized in that, include: A wrist bionic structure and a blood vessel bionic structure, wherein the wrist bionic structure includes a bionic skin layer (1), an mounting layer (2) and a support layer, wherein the mounting layer (2) is disposed between the bionic skin layer (1) and the support layer; The biomimetic vascular structure includes an elastic tube (3), a peristaltic pump (4), and a liquid tank (5). One end of the elastic tube (3) is disposed in the mounting layer (2), and the other end is connected to the peristaltic pump (4). The peristaltic pump (4) is connected to the liquid tank (5).

2. The bionic wrist pulse generator according to claim 1, characterized in that: The biomimetic vascular structure also includes a vascular branch (6) and an injection pump (7). The vascular branch (6) is disposed within the mounting layer (2), and the injection pump (7) is connected to the vascular branch (6).

3. The bionic wrist pulse generator according to claim 2, characterized in that: The vascular branch (6) is a multi-level branch network structure, which includes at least a number of primary branch vessels (61), a number of secondary branch vessels (62), and a number of tertiary vascular branches (63). The inner diameters of the primary branch vessels (61), secondary branch vessels (62), and tertiary vascular branches (63) decrease sequentially.

4. The bionic wrist pulse generator according to claim 2, characterized in that: The elastic tube (3) is disposed on the side of the vascular branch (6) near the support layer.

5. The bionic wrist pulse generator according to claim 1, characterized in that: Multiple sets of piezoelectric ceramic sheets are provided in the mounting layer (2). The multiple sets of piezoelectric ceramic sheets are arranged sequentially along the extension direction of the elastic tube (3). Each set of piezoelectric ceramic sheets includes two piezoelectric ceramic sheets (8). The two piezoelectric ceramic sheets (8) in the same set are arranged opposite each other on the circumferential outer side of the elastic tube (3).

6. The bionic wrist pulse generator according to claim 1, characterized in that: The biomimetic skin layer (1) is made of Ecoflex material.

7. The bionic wrist pulse generator according to claim 1, characterized in that: The mounting layer (2) is made of PDMS material.

8. The bionic wrist pulse generator according to claim 1, characterized in that: The support layer includes a foamed silicone layer (9) and a rigid support layer (10), wherein the foamed silicone layer (9) is disposed between the mounting layer (2) and the rigid support layer (10).

9. The bionic wrist pulse generator according to claim 1, characterized in that: One end of the elastic tube (3) is embedded in the mounting layer (2).

10. The bionic wrist pulse generator according to claim 2, characterized in that: The vascular branch (6) is embedded within the mounting layer (2).

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