Automatic continuous supply device for trace liquid medicine

Abstract

The invention provides an automatic continuous supply device for trace liquid medicine. The automatic continuous supply device comprises a liquid medicine storage and supply assembly and a trace liquid medicine quantitative suction assembly which are connected through a liquid conveying pipeline provided with a temporary storage pipe. The liquid medicine storage and supply assembly comprises an injection bottle driving mechanism, a locking mechanism and a puncture mechanism, and a plurality of loading positions containing injection bottles are arranged in the injection bottle driving mechanism. A needle head connected with one end of the medicine conveying pipeline is arranged at the tail end of the puncturing mechanism, a puncturing station is arranged under the puncturing mechanism, and when a certain loading position is located at the puncturing station, the loading position is locked through the locking mechanism, and the closed end of the injection bottle in the loading position is punctured through the needle head; the trace liquid medicine quantitative suction assembly comprises two peristaltic pumps, the first peristaltic pump is used for conveying the liquid medicine in the injection bottle on the puncture station into the buffer tube, and the second peristaltic pump is used for accurately conveying the liquid medicine in the buffer tube to the other end of the medicine conveying pipeline. According to the invention, high-precision automatic continuous supply of trace liquid medicine can be realized.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of medical equipment, and particularly relates to a micro-liquid medicine automatic continuous supply device. BACKGROUND

[0002] For the continuous delivery of micro-liquid medicine, such as medical scenarios with high requirements for medicine dosage precision, such as vaccination and hormone injection, existing medicine supply equipment generally adopts a single-pump driving combined with manual bottle changing operation mode. Such equipment realizes microliter-level medicine delivery through precise mechanical control, but still faces systematic technical bottlenecks in actual application.

[0003] In the prior art, the medicine bin capacity of the continuous medicine supply device is limited by the single-bottle loading capacity. After completing the single-bottle medicine supply, the process needs to be interrupted for manual bottle changing. The automation degree of this mode is low. When a small bottle of medicine is used up, the entire delivery process must be paused to wait for the medical staff to manually replace a new medicine bottle. This frequent manual intervention and process interruption not only seriously affects the continuity and overall efficiency of medicine supply, but also cannot meet the needs of high-throughput and uninterrupted operation. In terms of continuous supply capacity, the medicine bin capacity of existing equipment is usually limited by the loading capacity of a single injection bottle, and there is a lack of large-capacity medicine storage and continuous supply design, which fundamentally limits the ability of long-term uninterrupted operation.

[0004] The conventional single-pump system needs frequent manual intervention in long-term operation, which seriously affects the efficiency of medicine delivery. In terms of medicine delivery precision control, the traditional single-pump system has inherent defects. The system directly extracts medicine from the medicine bottle for delivery. When the liquid level in the medicine bottle is low or is about to be extracted, air is easily sucked into the pipeline. For micro-dosing, the small amount of air sucked in will also cause the volume of the output medicine to be inaccurate, thereby failing to strictly guarantee the dosage precision and posing a hidden danger to medicine safety.

[0005] In terms of pipeline design, many devices use a split-type or complex-joint-containing pipeline structure. This design easily causes medicine residue in the inner wall of the pipeline and the connection, which will soon lead to waste of expensive medicine and further affect the precision of medicine delivery. SUMMARY

[0006] The present application aims to at least partially solve one of the technical problems in the related art.

[0007] To this end, the micro-liquid medicine automatic continuous supply device provided by the present application can realize high-precision automatic continuous supply of micro-liquid medicine.

[0008] To achieve the above-mentioned purposes, the present application adopts the following technical solutions:

[0009] The application provides a micro-liquid medicine automatic continuous supply device, which comprises a medicine storage and supply assembly and a micro-liquid medicine quantitative suction assembly connected through a liquid delivery pipeline provided with a buffer tube.

[0010] The medicine storage and supply assembly comprises an injection bottle driving mechanism, a locking mechanism and a puncture mechanism, the injection bottle driving mechanism is internally provided with a plurality of loading positions, each loading position contains an injection bottle; the puncture mechanism is provided with a needle head connected with one end of the medicine delivery pipeline, and a puncture station is arranged below the needle head; when a loading position is in the puncture station, the locking mechanism is used for locking the loading position, and the needle head is used for puncturing the closed end of the injection bottle in the loading position.

[0011] The micro-liquid medicine quantitative suction assembly comprises two peristaltic pumps, the first peristaltic pump is used for delivering the medicine in the injection bottle in the puncture station into the buffer tube, and the second peristaltic pump is used for accurately delivering the medicine in the buffer tube to the other end of the medicine delivery pipeline.

[0012] In some embodiments, the injection bottle driving mechanism comprises a driving motor, an encoder and a transmission member, the transmission member is provided with a plurality of loading positions, each loading position is used for containing one injection bottle; the driving motor is arranged above the loading positions by a support plate, the encoder is coaxially connected with the driving motor and is used for detecting the rotation angle of the driving motor; the transmission member comprises meshed gears and a transmission chain, the transmission chain is constrained in an annular track, and the gears are coaxially connected below the driving motor; a plurality of loading positions are uniformly fixed to the top end of the transmission chain and synchronously move with the transmission chain.

[0013] In some embodiments, the locking mechanism comprises a suction switch and a claw connected with the suction switch, the claw faces the loading position in the puncture station, a clamping groove matched with the claw is arranged on the side wall of each loading position, and the suction switch is used for separating or contacting the claw and the loading position in the puncture station.

[0014] In some embodiments, the suction switch adopts a push-pull electromagnet.

[0015] In some embodiments, the puncture mechanism comprises a linear motor mounted on a support frame, the needle head is fixed to the output end of the linear motor, the support frame is fixed to a support plate, and a hole position for the needle head to pass through is formed in the support plate.

[0016] In some embodiments, the first peristaltic pump and the second peristaltic pump are fixed side by side on a support.

[0017] In some embodiments, the first peristaltic pump and the second peristaltic pump do not work at the same time, and the flow rate of the first peristaltic pump is set to be greater than that of the second peristaltic pump.

[0018] In some embodiments, the flow rate of the first peristaltic pump is set to be 8 mL / min to 12 mL / min, and the flow rate of the second peristaltic pump is set to be 0.1 mL / min.

[0019] In some embodiments, the buffer tube is a burette.

[0020] In some embodiments, before the medicine is supplied by the micro-liquid automatic continuous supply device, the infusion pipeline is wetted by the liquid to be supplied.

[0021] The present application has the following characteristics and beneficial effects:

[0022] For medical scenarios such as vaccination, hormone injection, etc. which have very high requirements for drug dosage accuracy, the present application develops a kind of automatic continuous micro-liquid drug supply device, which is specially used to meet the needs of clinical continuous, accurate and safe delivery of micro-liquid drugs. The device integrates high-precision driving control technology, which can realize the accurate control of microliter-level liquid drug flow, and the control error is very small, which ensures that each drug supply is stable and reliable, and is suitable for scenarios such as vaccination, hormone regulation, immunotherapy, etc. which need long-term or multiple small-dose drug delivery. The built-in large-capacity drug storage in the device and the optimized design of the micro-liquid drug quantitative suction assembly and the low-residual flow path structure formed by the infusion pipeline with a buffer tube effectively ensure the continuous supply of liquid medicine while greatly reducing the liquid residue and waste, thereby reducing the use cost and reducing the risk of cross contamination between drugs. In the design of the supply pipeline, the present application uses an integrated through type hose as the infusion pipeline. When the hose is used for the first time, the inner wall of the hose can be wetted with the drug to be supplied, which can greatly reduce the liquid residue in the flow path. Compared with the split type pipeline design, the through pipeline can effectively reduce the liquid residue due to its smooth structure inside the pipeline. In terms of drug supply accuracy, the design of double peristaltic pumps in series can ensure that air is not sucked in during drug supply, which can ensure that the single drug supply accuracy is 0.1 mL. The device supports full-process automatic drug supply function without frequent manual intervention, which not only significantly reduces the operation burden of medical staff, but also improves the efficiency and consistency of the drug supply process. The modular structure design of the present application makes the device have good compatibility, which can flexibly adapt to various types of drugs and meet the diversified needs in complex medical environments. In addition, the device of the present application adopts a lightweight body design, which is convenient to use in hospitals, clinics and even outdoor vaccination sites, improving the portability and application range of the device. Combined with low-power operation mode and the selection of environmentally friendly materials, the drug supply device not only saves energy during use, but also embodies good sustainability, which meets the trend of modern medical devices towards green and intelligent development. Overall, the automatic continuous micro-liquid drug supply device of the present application takes automation technology as the core highlight, and fully improves the reliability, safety and operation efficiency of micro-liquid drug delivery under the premise of ensuring high-precision drug supply, which provides a more advanced and intelligent solution for modern medicine. BRIEF DESCRIPTION OF DRAWINGS

[0023] Figure 1 is a structure schematic diagram of a micro-liquid automatic continuous supply device provided by an embodiment of the present application;

[0024] Figure 2 is Figure 1 the structure schematic diagram of the drug storage and drug supply assembly in the supply device shown in

[0025] Figure 3 is Figure 1The cooperation between the puncture mechanism and the locking mechanism in the shown supply device is shown schematically;

[0026] Figure 4 is Figure 1 The structure of the micro-liquid medicine quantitative suction assembly in the shown supply device is shown schematically;

[0027] In the figure:

[0028] 1. A medicine storage and supply assembly, 11. An injection bottle driving mechanism, 111. A driving motor, 112. An encoder, 113. A transmission member, 113a. A gear, 113b. A transmission chain, 114. A loading position, 115. An injection bottle, 116. A support plate, 117. An annular track, 12. A locking mechanism, 121. A clamping jaw, 122. A suction switch, 13. A puncture mechanism, 131. A support frame, 132. A linear motor, 133. A needle;

[0029] 2. A micro-liquid medicine quantitative suction assembly, 21. A first peristaltic pump, 22. A second peristaltic pump, 23. A support base;

[0030] 3. An infusion pipeline, 31. A buffer tube. DETAILED DESCRIPTION

[0031] In order to make the purpose, technical scheme and advantages of the present application more clear, the present application is further described in detail below in combination with the drawings and examples. It should be understood that the specific examples described herein are only used to explain the present application and do not limit the present application.

[0032] On the contrary, the present application covers any substitution, modification, equivalent method and scheme defined by the claims on the essence and scope of the present application. Further, in order to make the public better understand the present application, some specific details are described in the following detailed description of the present application. The present application can also be completely understood without the description of these details by those skilled in the art.

[0033] The structures, proportions, sizes, etc. shown in the drawings of the present specification are only used to cooperate with the content disclosed in the specification, to be understood and read by those skilled in the art, and are not used to limit the defined conditions of the implementation of the present application, so they do not have technical significance. Any modification of the structure, change of the proportional relationship or adjustment of the size, without affecting the effect and purpose that can be achieved by the present application, should still fall within the scope of the technical content disclosed by the present application. At the same time, the terms such as "upper", "lower", "left", "right", "middle" and "one" in the present specification are only for the convenience of clear description, and are not used to limit the scope of the implementation of the present application. The change or adjustment of the relative relationship, without substantially changing the technical content, is also considered as the implementation of the present application.

[0034] The present application is illustrated by way of example and not limitation in the following description, with reference to the accompanying drawings, in which:

[0035] Referring to Figures 1-4 The micro-liquid automatic continuous supply device provided by the embodiment of the present application comprises a liquid storage and supply assembly 1 and a micro-liquid quantitative pumping assembly 2 connected through a liquid delivery pipeline 3 provided with a buffer tube 31.

[0036] The liquid storage and supply assembly 1 comprises an injection bottle driving mechanism, a locking mechanism and a puncture mechanism. The injection bottle driving mechanism is provided with a plurality of loading positions, each of which contains an injection bottle. The puncture mechanism is provided with a needle connected to one end of the liquid delivery pipeline 3. The puncture position is located directly below the needle. When a loading position is at the puncture position, the locking mechanism is used to lock the loading position, and the needle is used to puncture the closed end of the injection bottle in the loading position.

[0037] The micro-liquid quantitative pumping assembly 2 comprises two peristaltic pumps fixed on a support. The first peristaltic pump is used to deliver the liquid in the injection bottle at the puncture position to the buffer tube, and the second peristaltic pump is used to accurately deliver the liquid in the buffer tube to the other end of the liquid delivery pipeline 3.

[0038] In some embodiments, the liquid storage and supply assembly 1 and the micro-liquid quantitative pumping assembly 2 are arranged side by side and connected through the liquid delivery pipeline 3.

[0039] In some embodiments, the liquid storage and automatic supply assembly 1 comprises an injection bottle driving mechanism 11, a locking mechanism 12 and a puncture mechanism 13. Wherein:

[0040] The injection bottle driving mechanism 11 comprises a driving motor 111, an encoder 112, a transmission member 113, a plurality of loading positions 114 arranged on the transmission member 113, each of the loading positions 114 being used for accommodating one injection bottle 115; the driving motor 111 is arranged above all the loading positions 114 by a support plate 116, the encoder 112 is coaxially connected with the driving motor 111 and is used for detecting the rotation angle of the driving motor 111; the transmission member 113 comprises a gear 113a and a transmission chain 113b which are engaged with each other, the transmission chain 113b is constrained in an annular track 117, the gear 113a is coaxially connected to the lower portion of the driving motor 111 by a key connection mode, the gear 113a is driven to rotate by the driving motor 111, and then the transmission chain 113b is driven to move in the annular track 117 in a circulating mode; the plurality of loading positions 114 are uniformly fixed to the top end of the transmission chain 113b and move synchronously with the transmission chain 113b.

[0041] The locking mechanism 12 comprises a suction switch 122 and a claw 121 connected with the suction switch 122, the claw 121 is arranged on the loading position 114 in the puncture station and faces the top end of the transmission chain 113b, a clamping groove matched with the claw 121 is arranged on the side wall of each of the loading positions 114, when the suction switch 122 is powered, the suction switch 122 is closed, the claw 121 is separated from the loading position 114 in the puncture station, so that the locking mechanism 122 is in an unlocked state; when the suction switch 122 is powered off, the suction switch 122 is opened, the claw 121 is in contact with the loading position 114 in the puncture station, and the loading position 114 is locked.

[0042] The puncture mechanism 13 comprises a linear motor 132 mounted on a support frame 131 and a needle 133 fixed to the output end of the linear motor 132, the support frame 131 is fixed to the support plate 116 and a hole position for the needle 133 to pass through is formed in the support plate 116, the needle 133 is located directly above the puncture station, under the driving of the linear motor 132, the needle 133 moves towards the puncture working position below, and then the injection bottle 115 in the loading position 114 is punctured.

[0043] Optionally, in one specific embodiment of the present application, the driving motor 111 adopts a TST42-40R type stepping motor of Yingpengfei, the encoder 112 adopts a UMot2 phase number encoder, the injection bottle 115 adopts a vial, the vial is filled with liquid medicaments (such as vaccines, hormones, etc.) required for injection, each of the loading positions 114 is a cylindrical structure matched with the size of the injection bottle 115, the suction switch 122 adopts a push-pull electromagnet, and the linear motor 132 adopts a direct current electric push rod.

[0044] In some embodiments, the micro-liquid medicine quantitative suction assembly 2 is mainly composed of a first peristaltic pump 21, a second peristaltic pump 22 and a support (specifically a metal frame) 23, which plays a key role in the accurate quantitative suction of micro-liquid medicine. The support 23 serves as a supporting and fixed main structure, and has threaded holes at the bottom, which can be fastened to the workbench to ensure stable installation of the entire micro-liquid medicine quantitative suction assembly 2 without displacement or loosening. At the same time, in order to ensure the stable installation of the peristaltic pump and its reasonable layout in the micro-liquid medicine quantitative suction assembly 2, the bottom of the support 23 is also provided with several (such as 8) larger threaded holes, which are used to fix the first peristaltic pump 21 and the second peristaltic pump 22, respectively. The bottom of the first peristaltic pump 21 is connected to the support 23 by a stud and is installed on the right side inside the support 23, ensuring the stability of the first peristaltic pump 21 and establishing its accurate relative position in the micro-liquid medicine quantitative suction assembly 2, so that it can smoothly perform the task of extracting liquid medicine in subsequent operations. The second peristaltic pump 22 is installed on the left side inside the support 23 in the same way and ensures the relative positional relationship between the first peristaltic pump 21 and the second peristaltic pump 22, so that it can maintain high precision and stability when performing the task of accurate quantitative suction. The first peristaltic pump 21 and the second peristaltic pump 22 both adopt existing commercial peristaltic pumps. The flow rate of the first peristaltic pump 21 is set to 8 mL / min-12 mL / min (10 mL / min in this embodiment), which aims to quickly extract all the liquid medicine in the injection bottle 115; the flow rate of the second peristaltic pump 22 is set to 0.1 mL / min, which aims to accurately control the accuracy of the drug dose to 0.1 mL.

[0045] The overall working process of the micro-liquid medicine automatic continuous supply device provided by the embodiment of the present application is as follows: first, the liquid medicine storage and medicine supply assembly 1 works, the driving motor 111 drives the gear set 113a, and then the transmission chain 12 moves, the encoder 112 detects that the target injection bottle 115 reaches the puncture station, the driving motor 11 stops rotating; the suction switch 122 is energized, the pawl 121 extends and inserts into the groove on the side wall of the loading position 114, locking the position of the injection bottle 115. The linear motor 132 drives the needle 133 to move downward and penetrate the rubber plug on the top of the injection bottle 115, specifically as Figure 3The micro-liquid medicine quantitative suction assembly 2 works, the first peristaltic pump 21 starts and extracts all the liquid medicine in the injection bottle 115 into the infusion pipeline 3, and temporarily stores it in the buffer tube 31 (specifically a Mohfis dropper) 31, which ensures that the liquid medicine is completely transferred from the injection bottle, providing a basis for subsequent accurate quantification, and the first peristaltic pump 21 stops working. The second peristaltic pump 22 starts to accurately extract the specified amount of liquid medicine, which can reach 0.1 mL, from the buffer tube 31 to the output end of the infusion pipeline 3, realizing the accurate supply of micro-liquid medicine. The reason for using two peristaltic pumps, the first peristaltic pump 21 and the second peristaltic pump 22, is based on the high precision requirement of liquid medicine quantitative suction. In order to ensure that the medicine supply precision reaches 0.1 mL, the liquid volume must be accurately controlled during the quantitative process. If the liquid medicine is directly extracted from the injection bottle 115 by one peristaltic pump, a small amount of air may be sucked in during the extraction process, thereby affecting the accuracy of the quantitative, resulting in that the extraction precision of the medicine cannot be strictly controlled to 0.1 mL. In contrast, using the buffer tube 31 as an intermediate storage and quantitative suction medium can effectively avoid the problem of air entering, improve the quantitative precision of the liquid medicine, and ensure that the dose of each medicine meets the strict standard requirements. This design of double peristaltic pumps with buffer tube makes the micro-liquid medicine quantitative suction assembly 2 work efficiently and meet the high-precision quantitative control requirements, ensuring the quality and safety of the medicine. Before using the medicine supply device, the infusion pipeline 3 can be wetted with the medicine to be supplied, which can avoid the residual liquid medicine in the pipeline from the buffer tube 31 to the output end, ensuring that the medicine supply precision is 0.1 mL. After completing the liquid extraction, the linear motor 132 retracts. The suction switch 122 is powered off, the pawl 121 retracts to release the loading position 114; the drive motor 111 drives the transmission chain 113b to step one position, so that the next injection bottle 115 enters the puncture position.

[0046] In the description of the present specification, the description of the terms "one embodiment", "some embodiments", "an example", "a specific example", or "some examples" and the like means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present application. In the present specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any appropriate manner in any one or more embodiments or examples. In addition, the different embodiments or examples described in the present specification and the features of the different embodiments or examples can be combined and combined by those skilled in the art without contradiction.

[0047] Although the examples of the present application have been shown and described above, it is understood that the above examples are exemplary, and are not to be construed as limiting the present application, and that changes, modifications, substitutions and variations can be made thereto by those of ordinary skill in the art within the scope of the present application.

Claims

1. A micro-volume continuous drug supply device, characterized in that, It includes a drug storage and supply component and a micro-volume drug dispensing component connected via an infusion tubing equipped with a buffer tube; The drug storage and dispensing assembly includes an injection vial driving mechanism, a locking mechanism, and a puncture mechanism. The injection vial driving mechanism has multiple loading positions, each of which contains an injection vial. The puncture mechanism has a needle at its end that is connected to one end of the drug delivery line. The puncture position is located directly below the needle. When a loading position is in the puncture position, the locking mechanism locks the loading position, and the needle punctures the closed end of the injection vial in the loading position. The micro-volume drug delivery assembly includes two peristaltic pumps. The first peristaltic pump is used to deliver the drug solution in the injection bottle at the puncture station to the buffer tube, and the second peristaltic pump is used to accurately deliver the drug solution in the buffer tube to the other end of the drug delivery line.

2. The automatic continuous micro-volume drug supply device according to claim 1, characterized in that, The injection vial driving mechanism includes a drive motor, an encoder, and a transmission component. The transmission component is equipped with multiple loading positions, each for accommodating one injection vial. The drive motor is mounted above the loading positions by a support plate. The encoder is coaxially connected to the drive motor and is used to detect the rotation angle of the drive motor. The transmission component includes meshing gears and a transmission chain. The transmission chain is constrained in a circular track, and the gears are coaxially connected to the lower part of the drive motor. The multiple loading positions are evenly fixed at the top of the transmission chain and move synchronously with the transmission chain.

3. The automatic continuous micro-volume drug supply device according to claim 1, characterized in that, The locking mechanism includes a pull switch and a claw connected to the pull switch. The claw faces the loading position on the puncture station. Each loading position has a slot on its side wall that matches the claw. The pull switch is used to separate or contact the claw with the loading position on the puncture station.

4. The automatic continuous micro-volume drug supply device according to claim 3, characterized in that, The latching switch uses a push-pull electromagnet.

5. The automatic continuous micro-volume drug solution supply device according to claim 1, characterized in that, The puncture mechanism includes a linear motor mounted on a support frame, the needle is fixed to the output end of the linear motor, the support frame is fixed to a support plate, and a hole is opened on the support plate for the needle to pass through.

6. The automatic continuous micro-volume drug supply device according to claim 1, characterized in that, The first peristaltic pump and the second peristaltic pump are fixed side by side on a support.

7. The automatic continuous micro-volume drug supply device according to claim 1, characterized in that, The first peristaltic pump and the second peristaltic pump do not operate simultaneously, and the flow rate of the first peristaltic pump is set to be greater than the flow rate of the second peristaltic pump.

8. The automatic continuous micro-volume drug supply device according to claim 1, characterized in that, The flow rate of the first peristaltic pump is set to 8 mL / min to 12 mL / min, and the flow rate of the second peristaltic pump is set to 0.1 mL / min.

9. The automatic continuous micro-volume drug solution supply device according to claim 1, characterized in that, The buffer tube is a Mofee dropper.

10. The automatic continuous supply device for micro-volume medicine solution according to any one of claims 1 to 9, characterized in that, Before administering medication using the aforementioned micro-volume continuous drug supply device, the infusion tubing is moistened with the medication to be supplied.

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