Section observation device for oncology pathological research

Abstract

The slice observation device comprises a slice table, a slice groove is concavely formed in the top end of the slice table, a plurality of liquid draining openings are formed in the inner bottom wall of the slice groove, and a detachable objective table is further arranged on the inner bottom wall of the slice groove; a plurality of sample grooves are formed in the top of the objective table, and slicing assemblies matched with the sample grooves are mounted on the side walls of the slicing grooves; the top of the slicing table is further connected with a portal frame, and the lower end of the portal frame is provided with a pressing and holding assembly used for pressing and holding a tumor sample; the top of the portal frame is further rotationally connected with a multifunctional supporting arm. Compared with the prior art, the slice observation device for the oncology pathological research has the advantages that the slice observation device is convenient to operate and use, multiple sample slicing can be carried out, and the samples can be conveniently transferred and directly observed.

Description

Technical Field

[0001] This invention relates to the field of oncology pathology research equipment technology, specifically to a slide observation device for oncology pathology research. Background Technology

[0002] In oncology pathology research, the examination of tumor samples by section is a crucial step. Traditional sectioning devices have many shortcomings, such as unstable sample fixation during the sectioning process, which can easily lead to uneven sections or sample damage.

[0003] The placement and transfer of samples after slicing are inconvenient, increasing the difficulty of operation and the risk of sample contamination; the observation device has limited functionality and cannot meet diverse research needs.

[0004] Therefore, developing a new type of slice observation device is of great practical significance. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to overcome the above-mentioned technical defects and provide a slide observation device for oncology pathology research that is easy to operate and use, can perform multi-sample slicing, and facilitates sample transport and direct observation.

[0006] To solve the above-mentioned technical problems, the technical solution provided by the present invention is as follows: a slide observation device for oncology pathology research, including a slide stage, a slide groove is provided in the upper part of the slide stage, a plurality of drainage ports are formed in the bottom wall of the slide groove, and a removable loading stage is also provided in the bottom wall of the slide groove.

[0007] The top of the stage has several sample slots, and the sidewalls of the slicing slots are fitted with slicing assemblies that are designed to match the sample slots.

[0008] The top of the slicing stage is also connected to a gantry frame, and the lower end of the gantry frame is equipped with a holding component for holding the tumor sample.

[0009] The top of the gantry is also rotatably connected to a multi-functional support arm, and an observation platform is integrally connected to the end of the multi-functional support arm. A slot is formed on the observation platform, and a positioning slot for placing a loading platform is formed on the top of the gantry.

[0010] Preferably, the inner wall of the slicing groove is further provided with a plurality of nozzles along its circumference, and the nozzles are positioned facing the stage.

[0011] Preferably, the bottom wall of the stage is provided with a magnetic suction plate, and the bottom wall of the slicing groove cooperates with the magnetic suction plate to form a magnetic suction structure.

[0012] Preferably, the slicing groove is provided with a first blade opening, and the top of the stage is recessed with a groove, and a second blade opening is provided on the groove corresponding to the position of the first blade opening;

[0013] A slicing blade is inserted between the first blade tip and the second blade tip.

[0014] Preferably, the tail end of the slicing blade has a push plate.

[0015] Preferably, the pressing assembly includes a cylinder installed at the top of the gantry and a pressing block located at the lower end of the cylinder.

[0016] Preferably, a stop flange is formed at the bottom of the slot.

[0017] Preferably, a magnetic suction groove is formed in the positioning groove.

[0018] Preferably, the cross-section of the multi-functional support arm is L-shaped;

[0019] The top of the gantry frame is fitted with a multi-functional support arm to form a rotating collar.

[0020] The advantages of this invention compared with the prior art are: through the holding component and the magnetic fixation structure, the tumor sample and the stage can be firmly fixed, effectively preventing the movement of the sample and the stage during the slicing process, and improving the accuracy and quality of the slicing.

[0021] The removable stage design facilitates sample placement and transfer; the inclusion of a drain port and spray nozzle makes it easy to clean up liquids generated during slicing, keeping the device clean.

[0022] The slots and frames on the observation platform can be used to place different tools and sample slices, meeting diverse research needs and facilitating widespread use. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of a slide observation device used in oncology pathology research.

[0024] Figure 2 This is a schematic diagram of a second-view structure for a slide observation device used in oncology pathology research.

[0025] Figure 3 This is a schematic diagram of a third-view structure for a slide observation device used in oncology pathology research.

[0026] As shown in the figure: 1. Slicing stage, 2. Slicing groove, 3. Drain outlet, 4. Stage, 5. Sample groove, 6. Gantry frame, 7. Multifunctional support arm, 8. Observation table, 9. Groove opening, 10. Positioning groove, 11. Nozzle, 12. Blade tip one, 13. Groove, 14. Blade tip two, 15. Slicing blade, 16. Push plate, 17. Cylinder, 18. Pressing block, 19. Stop flange, 20. Rotating collar. Detailed Implementation

[0027] The present invention will now be described in further detail with reference to the accompanying drawings.

[0028] Combined with appendix Figure 1-3 As shown, a slide observation device for oncology pathology research includes a slide stage 1, a slide groove 2 recessed at the top of the slide stage 1, a plurality of drainage ports 3 formed in the bottom wall of the slide groove 2, and a removable loading platform 4 provided in the bottom wall of the slide groove 2.

[0029] Among them, the top of the stage 4 has a number of sample slots 5, and the side wall of the slicing slot 2 is equipped with a slicing assembly that matches the sample slots 5.

[0030] The top of the slicing stage 1 is also connected to a gantry 6, and the lower end of the gantry 6 is equipped with a holding component for holding the tumor sample.

[0031] The holding assembly includes a cylinder 17 mounted on the top of the gantry 6 and a pressing block 18 located at the lower end of the cylinder 17, which is used to press the tumor sample.

[0032] After slicing, a multi-functional support arm 7 is rotatably connected to the top of the gantry 6. An observation platform 8 is integrally connected to the end of the multi-functional support arm 7. A slot 9 is formed on the observation platform 8. A positioning slot 10 for placing the stage 4 is formed on the top of the gantry 6. The positioning slot 10 is used for positioning, and different observation components are placed in conjunction with the slot 9 to observe the sliced ​​sample.

[0033] In one embodiment:

[0034] The inner wall of the slicing groove 2 is also connected with several nozzles 11 along its circumference. The nozzles 11 are set towards the stage 4. The bottom wall of the stage 4 is provided with a magnetic suction plate. The inner bottom wall of the slicing groove 2 and the magnetic suction plate form a magnetic suction structure.

[0035] In one embodiment:

[0036] When slicing, a blade opening 12 is provided on the slicing groove 2, and a groove 13 is recessed in the top of the stage 4. A blade opening 14 is provided on the groove 13 corresponding to the position of the blade opening 12. A slicing knife 15 is inserted between the blade opening 12 and the blade opening 14.

[0037] The end of the slicing blade 15 has a push plate 16, which facilitates manual or electric pushing of the slices.

[0038] When placing the observation component, a retaining flange 19 is formed at the bottom of the slot 9 to facilitate the engagement of the observation component.

[0039] When in use, a magnetic suction groove is formed in the positioning groove 10, and the stage 4 is used to magnetically attract the object through the magnetic suction groove.

[0040] In one embodiment, the cross-section of the multi-functional support arm 7 is L-shaped;

[0041] The top of the gantry frame 6 and the multi-functional support arm 7 form a rotating collar 20, which allows the multi-functional support arm 7 to be rotated for easy cleaning and use.

[0042] In specific implementation, the stage is placed in the slicing slot. The stage is firmly fixed in the slot by the magnetic attraction between the magnetic plate and the bottom wall of the slicing slot. The microtome is inserted between blade tip one and blade tip two, ensuring a secure installation. The cylinder is activated, causing the pressure block to press down and hold the tumor sample, ensuring it does not move during slicing. An appropriate amount of liquid, such as cleaning or fixing solution, is sprayed onto the stage through a nozzle, pushing the push plate at the tail of the microtome to slice the tumor sample along the sample slot. Liquid generated during slicing is drained from the slicing slot through a drain port. After slicing, the stage is removed from the slicing slot and placed in the positioning slot at the top of the gantry. The angle of the multi-functional support arm is adjusted according to observation needs to position the observation stage for observation.

[0043] The contents not described in detail in this specification are existing technologies known to those skilled in the art.

[0044] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0045] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0046] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature being directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature being directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0047] The present invention and its embodiments have been described above. This description is not restrictive, and the accompanying drawings are only one embodiment of the present invention; the actual structure is not limited thereto. In conclusion, if those skilled in the art are inspired by this description and design similar structures and embodiments without departing from the spirit of the invention, such designs should fall within the protection scope of the present invention.

Claims

1. A slide observation device for oncology pathology research, characterized in that: Includes a slicing stage (1), the top of the slicing stage (1) is recessed with a slicing groove (2), the bottom wall of the slicing groove (2) is formed with a plurality of drain outlets (3), and the bottom wall of the slicing groove (2) is also provided with a removable platform (4). The top of the stage (4) is formed with a plurality of sample slots (5), and the side wall of the slicing slot (2) is equipped with a slicing assembly that matches the sample slots (5); The top of the slicing stage (1) is also connected to a gantry frame (6), and the lower end of the gantry frame (6) is equipped with a holding component for holding the tumor sample; The top of the gantry (6) is also rotatably connected to a multi-functional support arm (7), and the end of the multi-functional support arm (7) is integrally connected to an observation platform (8). A slot (9) is formed on the observation platform (8), and a positioning slot (10) for placing a platform (4) is formed on the top of the gantry (6).

2. The slide observation device for oncology pathology research according to claim 1, characterized in that: The inner wall of the slicing groove (2) is also provided with a number of nozzles (11) along its circumference, and the nozzles (11) are set towards the stage (4).

3. The slide observation device for oncology pathology research according to claim 1, characterized in that: The bottom wall of the stage (4) is provided with a magnetic suction plate, and the bottom wall of the slicing groove (2) cooperates with the magnetic suction plate to form a magnetic suction structure.

4. The slide observation device for oncology pathology research according to claim 3, characterized in that: The slicing groove (2) is provided with a blade opening (12), and the top of the stage (4) is recessed with a groove (13), and a blade opening (14) is provided on the groove (13) corresponding to the position of the blade opening (12). A slicing blade (15) is inserted between the first blade opening (12) and the second blade opening (14).

5. The slide observation device for oncology pathology research according to claim 3, characterized in that: A push plate (16) is formed at the tail end of the slicing blade (15).

6. The slide observation device for oncology pathology research according to claim 1, characterized in that: The pressing assembly includes a cylinder (17) installed at the top inside the gantry (6) and a pressing block (18) located at the lower end of the cylinder (17).

7. The slide observation device for oncology pathology research according to claim 1, characterized in that: A stop flange (19) is formed at the bottom of the groove (9).

8. A slide observation device for oncology pathology research according to claim 7, characterized in that: A magnetic groove is formed inside the positioning groove (10).

9. A slide observation device for oncology pathology research according to claim 8, characterized in that: The cross-section of the multi-functional support arm (7) is L-shaped; The top of the gantry (6) is fitted with a multi-functional support arm (7) to form a rotating collar (20).

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