Calcitonin luminescence detection kit and detection method and application thereof

A calcitonin luminescent detection kit designed using alkaline phosphatase chemiluminescence assay overcomes the sensitivity limitations of traditional detection methods by combining magnetic beads and alkaline phosphatase, achieving highly sensitive and stable calcitonin detection suitable for dynamic monitoring during clinical treatment.

CN120971402APending Publication Date: 2025-11-18BEIJING STRONG BIOTECH INC
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Patent Information

Application Number
CN202511141223.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-08-14
Publication Date
2025-11-18

AI Technical Summary

Technical Problem

Traditional CT scans have poor sensitivity in detecting calcitonin within the reference range, making it difficult to meet the requirements for high-sensitivity detection.

Method used

The alkaline phosphatase chemiluminescence method was used, and a kit was designed by using magnetic beads coated with a first calcitonin antibody and alkaline phosphatase linked with a second calcitonin antibody. The kit combines magnetic field separation and chemiluminescence detection to achieve high-sensitivity detection of calcitonin.

Benefits of technology

It achieves high sensitivity and automation in calcitonin detection, is suitable for dynamic observation during treatment, has good sample correlation, good stability and precision, and meets the needs of clinical testing.

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Abstract

The invention relates to a calcitonin luminescence detection kit and a detection method and application thereof. Specifically, the invention provides the high-sensitivity calcitonin luminescence detection kit, the high-sensitivity calcitonin luminescence detection kit comprises a first reagent and a second reagent, and the first reagent comprises magnetic beads connected with first protein; the second reagent comprises alkaline phosphatase connected with the second protein. The kit improves the detection accuracy and the sample coincidence rate.
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