Tissue treatment device

By designing a multifunctional tissue processing device, the problems of large footprint and high temperature requirements associated with multiple constant-temperature shakers were solved, enabling efficient and space-saving tissue transparency and staining on a single device, thus improving processing quality.

CN120992282APending Publication Date: 2025-11-21NUOHAI LIFE SCIENCE (SHANGHAI) CO LTD
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Patent Information

Application Number
CN202511145449.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-08-15
Publication Date
2025-11-21

AI Technical Summary

Technical Problem

In existing technologies, tissue clearing and staining processes require multiple constant-temperature shakers, which occupy a large area and are difficult to meet the processing conditions with different temperature requirements.

Method used

A tissue processing device was designed, comprising a shell module, a constant temperature chamber module, and an oscillation module. By stacking temperature control chamber units and an angle adjustment module, the temperature and oscillation of multiple temperature control chamber units are controlled, reducing the equipment footprint. The oscillation module also improves the uniform contact between the tissue and the solution.

Benefits of technology

It enables clearing and staining processes under different conditions to be performed simultaneously on a single device, reducing the equipment footprint and improving the quality and efficiency of tissue processing.

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Abstract

The invention relates to the technical field of biology, in particular to a tissue treatment device which comprises a shell module, a constant-temperature bin module and an oscillation module. The constant-temperature bin module is arranged above the oscillation module, and the constant-temperature bin module and the oscillation module are located in the shell module; the shell module comprises a control unit, a man-machine interaction unit, a front door and a shell; the constant-temperature bin module comprises a plurality of temperature control bin units and bin doors of the temperature control bin units; wherein test tube holes are formed in the temperature control bin units, and the temperature control bin units are stacked; the control unit is used for respectively controlling the temperature of each temperature control bin unit based on the temperature control instruction sent by the man-machine interaction unit; and the oscillation module is controlled to oscillate based on an oscillation instruction sent by the man-machine interaction unit so as to drive each temperature control bin unit to oscillate. Transparent and / or dyeing treatment under different conditions can be achieved at the same time, and the occupied area of equipment is reduced.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of biotechnology, and more particularly to a tissue processing device. BACKGROUND

[0002] Before the whole tissue is imaged, the tissue needs to be processed, such as transparentization and staining, to ensure that the inside of the tissue can be clearly photographed.

[0003] At present, the transparentization and staining of the tissue are generally carried out in a constant temperature shaker. Specifically, a plurality of centrifuge tubes are placed in the constant temperature shaker, each of which contains a tissue and a corresponding transparentization or staining solution, a temperature is set, and the components in the solution are replaced with the components in the tissue by constant shaking, so as to finally realize the transparentization or staining of the tissue.

[0004] Due to different temperature requirements or used solutions in the transparentization and staining processes, in order to improve the transparentization and staining efficiency, a plurality of constant temperature shakers are often used, which occupies a large area. SUMMARY

[0005] The present application is provided to solve the above problems in the prior art. The tissue processing device provided by the embodiments of the present application can simultaneously realize transparentization and / or staining processing under different conditions and reduce the equipment floor area.

[0006] The embodiments of the present application provide a tissue processing device, which comprises a shell module, a constant temperature bin module and an oscillation module.

[0007] The constant temperature bin module is arranged above the oscillation module, and the constant temperature bin module and the oscillation module are located in the shell module.

[0008] The shell module comprises a control unit, a human-computer interaction unit, a front door and a shell.

[0009] The constant temperature bin module comprises a plurality of temperature control bin units and bin doors of each temperature control bin unit, wherein a test tube hole is arranged in each temperature control bin unit, and each temperature control bin unit is arranged in a stacked manner.

[0010] The control unit is configured to control the temperature of each temperature control bin unit based on a temperature control instruction sent by the human-computer interaction unit, and control the oscillation of the oscillation module based on an oscillation instruction sent by the human-computer interaction unit to drive the oscillation of each temperature control bin unit.

[0011] The tissue processing device provided by the embodiment of the present application comprises a plurality of temperature control bin units, each of the temperature control bin units is arranged in a stack, thereby reducing the floor area. The control unit can control the temperature of each temperature control bin unit respectively, so that each temperature control bin unit can meet different condition requirements and realize different transparentization or dyeing processing. The oscillation module is used to make the tissue and the solution uniformly contact, thereby improving the tissue processing quality. BRIEF DESCRIPTION OF DRAWINGS

[0012] In the drawings, which are not necessarily drawn to scale, like numerals can describe similar components in different views. Like numerals having different letter suffixes can represent different instances of similar components. The drawings illustrate generally by way of example, and not by way of limitation, various embodiments discussed in the present document, as provided herein. The same reference numerals are used consistently throughout the drawings and the description to refer to the same or like components. Such embodiments are illustrative, and not intended to be exhaustive or limiting of the present devices and methods.

[0013] Figure 1 is a schematic diagram of a tissue processing device provided by an embodiment of the present application;

[0014] Figure 2 is a schematic diagram of a shell module provided by an embodiment of the present application;

[0015] Figure 3 is a schematic diagram of a tissue processing device provided by another embodiment of the present application;

[0016] Figure 4 is a schematic diagram of a constant-temperature bin module provided by an embodiment of the present application;

[0017] Figure 5 is a schematic diagram of a heating bin unit provided by an embodiment of the present application;

[0018] Figure 6 is a schematic diagram of a room-temperature bin unit and a refrigeration bin unit provided by an embodiment of the present application;

[0019] Figure 7 is a perspective view of an angle adjustment module provided by an embodiment of the present application;

[0020] Figure 8 is a top view of an angle adjustment module provided by an embodiment of the present application;

[0021] Figure 9 is a front view of an oscillation module provided by an embodiment of the present application;

[0022] Figure 10is a top view of an oscillation module provided by an embodiment of the present application. DETAILED DESCRIPTION

[0023] To make the skilled in the art better understand the technical solutions of the present application, the present application will be described in detail below in conjunction with the drawings and specific embodiments. The embodiments of the present application will be further described in detail below in conjunction with the drawings and specific embodiments, but not as a limitation on the present application. The terms "first", "second" and "third" used in the present application are only intended to distinguish the corresponding features, and do not necessarily represent the order, nor necessarily represent the singular form.

[0024] Reference Figure 1 and Figure 2 The embodiment of the present application provides a tissue processing device, comprising: a shell module 000, a constant temperature bin module 100 and an oscillation module 300;

[0025] The constant temperature bin module 100 is arranged above the oscillation module 300, and the constant temperature bin module 100 and the oscillation module 300 are located in the shell module 000;

[0026] The shell module 000 comprises a control unit 001, a human-computer interaction unit 002, a front door 003 and a shell 004;

[0027] The constant temperature bin module 100 comprises a plurality of temperature control bin units and bin doors 140 of each temperature control bin unit; wherein a test tube hole is arranged in the temperature control bin unit, and each temperature control bin unit is arranged in a stack;

[0028] The control unit 001 is used for controlling the temperature of each temperature control bin unit based on the temperature control instruction sent by the human-computer interaction unit 002; and controlling the oscillation of the oscillation module 300 based on the oscillation instruction sent by the human-computer interaction unit 002, so as to drive the oscillation of each temperature control bin unit.

[0029] The constant temperature bin module can comprise a plurality of temperature control bin units, and the embodiment of the present application is only illustrated by taking three as an example. The number and size of the test tube holes can be adjusted according to the business requirements, and 12 test tube holes are arranged in each temperature control bin unit in the embodiment of the present application.

[0030] The human-computer interaction unit can provide buttons or touch screens to receive temperature parameters input by the user. Each temperature control bin unit has an independent bin door to facilitate the independent control of the temperature of each temperature control bin unit.

[0031] In the embodiment of the present application, each temperature control bin unit is arranged in a stack, which can reduce the floor area. The control unit can control the temperature of each temperature control bin unit respectively, so that each temperature control bin unit can meet different condition requirements and realize different transparentization or staining processing. The oscillation module makes the tissue and the solution uniformly contact, thereby improving the tissue processing quality.

[0032] In an embodiment of the present application, as shown in Figure 3 The device further comprises an angle adjustment module 200;

[0033] The angle adjustment module 200 is located in the shell module 000, the constant-temperature warehouse module 100 is fixed on the angle adjustment module 200, and the angle adjustment module 200 is fixed on the oscillation module 300.

[0034] The control unit 001 is configured to control the movement of the angle adjustment module 200 based on the angle adjustment instruction sent by the human-computer interaction unit 002, so as to change the inclination angle of each temperature control warehouse unit.

[0035] In order to ensure that the liquid in the centrifugal tube is in sufficient contact with the tissue, the inclination angle of the temperature control warehouse unit is adjusted by the angle adjustment module in the embodiment of the present application. The user can set the inclination angle through the human-computer interaction unit, and the angle adjustment instruction can include the set inclination angle.

[0036] The temperature control warehouse unit comprises a warehouse body, a temperature control module, and a test tube hole arranged in the warehouse body, and each temperature control warehouse unit is arranged in a stacked manner. Taking the heating warehouse unit as an example, the warehouse body is a first warehouse body, and the temperature control module comprises a first outer plate, a first heat insulation plate, a heating plate, a first heat preservation layer, and a first temperature sensor.

[0037] In an embodiment of the present application, as shown in Figure 4 and Figure 5 The plurality of temperature control warehouse units comprise a heating warehouse unit 110.

[0038] The heating warehouse unit 110 comprises a first outer plate 111, a first heat insulation plate 112, a first warehouse body 113, a heating plate 114, a first heat preservation layer 115, a first temperature sensor 116, and a test tube hole 117 (not shown in the figure). Figure 4

[0039] The heating plate 114 is arranged around the outer side of the first warehouse body 113, the first temperature sensor 116 is arranged at the bottom of the first warehouse body 113 and away from the test tube hole, the heating plate 114, the first temperature sensor 116, and the first warehouse body 113 are wrapped in the first heat preservation layer 115, the first heat insulation plate 112 is arranged on the side of the first warehouse body 113, the heating plate 114, and the first heat preservation layer 115 close to the test tube hole, and the first outer plate 111 is arranged on the side of the first heat insulation plate 112 close to the test tube hole.

[0040] ​The heating plate 114 transmits the generated heat to the first chamber body 113, the first temperature sensor 116 is in contact with the first chamber body 113, and the collected temperature data is sent to the control unit 001. The control unit 001 sends the temperature data to the human-computer interaction unit 002, which provides the temperature data to the user. The control unit 001 controls the heating plate 114 based on the temperature control instructions sent by the human-computer interaction unit 002 to increase the temperature of the heating chamber unit 110.

[0041] The same type of temperature-controlled chamber unit can be included in the constant-temperature chamber module, or different types of temperature-controlled chamber units can be included, such as four heating chamber units, or two heating chamber units and two room temperature chamber units.

[0042] The heating plate is wrapped around the outside of the first chamber body, which facilitates uniform heating of the first chamber body and maintains the stability of the temperature of the first chamber body. Even if the chamber door is opened briefly, it will not cause fluctuations in the temperature of the first chamber body. The heating chamber unit can also be implemented through other structures, such as adjusting the position of the heating plate, adjusting the position of the first temperature sensor, adjusting the number of test tube holes, etc.

[0043] In an embodiment of the present application, as shown in Figure 4 and Figure 6 The plurality of temperature-controlled chamber units include a room temperature chamber unit 120.

[0044] The room temperature chamber unit 120 includes a second outer plate 121, a second heat insulation plate 122, a second chamber body 123, a heat conduction block 124, a semiconductor refrigeration sheet 125, a heat dissipation fin 126, an axial flow fan 127, a second temperature sensor 128, a second heat preservation layer 129, and a test tube hole 131. The axial flow fan 127 is installed outside the heat dissipation fin 126.

[0045] When the semiconductor refrigeration sheet 125 is forward energized, the side of the semiconductor refrigeration sheet 125 in contact with the second chamber body 123 is the cold end, and the side of the semiconductor refrigeration sheet 125 in contact with the heat dissipation fin 126 is the hot end. The cold end transmits the heat generated by the second chamber body 123 to the hot end, and the hot end transmits the heat to the heat dissipation fin 126. The axial flow fan 127 blows air into the heat dissipation fin 126 to transmit the heat of the heat dissipation fin 126 to the air.

[0046] When the semiconductor refrigeration sheet 125 is reverse energized, the side of the semiconductor refrigeration sheet 125 in contact with the second chamber body 123 is the hot end, and the side of the semiconductor refrigeration sheet 125 in contact with the heat dissipation fin 126 is the cold end. Heat is transmitted from the hot end to the second chamber body 123, and the cold end absorbs heat from the heat dissipation fin 126. The axial flow fan 127 blows air into the heat dissipation fin 126 to allow the heat dissipation fin 126 to absorb heat from the air.

[0047] The second temperature sensor 128 is in contact with the second chamber body 123, and sends the collected temperature data to the control unit 001, which sends the temperature data to the human-computer interaction unit 002, which provides the temperature data to the user. The control unit 001 controls the semiconductor refrigeration sheet 125 based on the temperature control instruction sent by the human-computer interaction unit 002 to adjust the temperature of the room temperature chamber unit 120.

[0048] In the embodiment of the present application, the semiconductor refrigeration sheet is an energy conversion technology that utilizes the Peltier effect of semiconductor materials to achieve refrigeration or heating. This phenomenon is completely reversible, and heat can be transferred in the opposite direction by simply changing the direction of the current. Therefore, both refrigeration and heating functions can be achieved on one semiconductor refrigeration sheet.

[0049] In one embodiment of the present application, as shown in Figure 4 , the plurality of temperature-controlled chamber units further include a refrigeration chamber unit 130;

[0050] The refrigeration chamber unit 130 and the room temperature chamber unit 120 have the same structure, and the control unit 001 controls the semiconductor refrigeration sheet 125 in the refrigeration chamber unit 130 based on the temperature control instruction to adjust the temperature of the refrigeration chamber unit 130. The temperature of the refrigeration chamber unit 130 is lower than that of the room temperature chamber unit 120.

[0051] Since the refrigeration chamber unit and the room temperature chamber unit have the same structure, the structure of the refrigeration chamber unit can be referred to Figure 6 , and the present application will not be described again. Unlike the room temperature chamber unit, the temperature of the refrigeration chamber unit is lower, for example, the temperature of the room temperature chamber unit is controlled at about 25°C, and the temperature of the refrigeration chamber unit is controlled at about 10°C.

[0052] In one embodiment of the present application, as shown in Figure 7 and Figure 8 , the angle adjusting module 200 includes an upper substrate 211, an upper substrate handle 2111, a lower substrate 212, a flip shaft 213, a straight slide rail 214, a rear connecting rod slider 215, a front connecting rod slider 216, a rear connecting rod 217, a front connecting rod 218, a latch 219, a pull rod 220, an electric push rod motor 221, a power-assisted tension spring 222, a horizontal limit position sensor 223, and a flip angle limit position sensor 224.

[0053] The push rod of the electric push rod motor 221 is connected to the pull rod 220 through the latch 219, and the pull rod 220 is threadedly connected to the front connecting rod slider 216.

[0054] When the control unit 001 controls the electric push rod motor 221 to move the push rod forward based on the angle adjustment instruction, the pull rod 220 moves forward synchronously, the front connecting rod slider 216 also moves forward synchronously, the front connecting rod 218 pulls the upper base plate 211 to overturn around the overturning shaft 213 to the horizontal position, the connecting rod 217 pushes the rear connecting rod slider 215 to move backward, the booster tension spring 222 is pulled open, until the upper base plate 211 moves to the horizontal state, the horizontal limit position sensor 223 is activated, sends a first feedback signal to the control unit 001, and the control unit 001 controls the electric push rod motor 221 to stop moving based on the first feedback signal.

[0055] When the control unit 001 controls the electric push rod motor 221 to move the push rod backward based on the angle adjustment instruction, the pull rod 220 moves backward synchronously, the front connecting rod slider 216 also moves backward synchronously, the front connecting rod 218 pushes the upper base plate 211 to overturn around the overturning shaft 213 to the maximum inclination angle state, the connecting rod 217 pulls the rear connecting rod slider 215 to move forward, the booster tension spring 222 is retracted, until the upper base plate 211 overturns to the maximum inclination angle state, the overturning angle limit position sensor 224 is activated, sends a second feedback signal to the control unit 001, and the control unit 001 controls the electric push rod motor 221 to stop moving based on the second feedback signal.

[0056] The control unit can control the position of the push rod of the electric push rod motor to move based on the angle control instruction, so as to control the inclination angle of the constant temperature bin module.

[0057] In an embodiment of the present application, as shown in Figure 9 and Figure 10 The oscillation module 300 comprises a circumferential oscillation table 301, a support frame 302, a small pulley 303, a large pulley 304, a belt 305, a rotating motor 306, and an eccentric shaft 307.

[0058] The rotating motor 306 is flange-fixed on the support frame 302, the small pulley 303 is connected to the output shaft of the rotating motor 306, and when the rotating motor 306 rotates, the power is transmitted to the large pulley 304 through the friction between the small pulley 303 and the large pulley 304 via the belt 305. The eccentric shaft 307 is distributed between the circumferential oscillation table 301 and the support frame 302, providing three-point circumferential rotation support for the circumferential oscillation table 301. The eccentric shaft 307 and the circumferential oscillation table 301, and the eccentric shaft 307 and the support frame 302 are connected by rotating pairs. The output shaft of the large pulley 304 is fixedly connected to one of the eccentric shafts 307.

[0059] The control unit 001 controls the rotating motor 306 to rotate based on the oscillation instruction, driving the circumferential oscillation table 301 to move.

[0060] The circumferential oscillation table 301 is fixedly connected with the lower base plate 212, the upper base plate 211 is fixedly connected with the constant-temperature bin module 100, and the control unit 001 controls the rotation speed of the rotating motor 306, so as to realize the circumferential vibration frequency control of the constant-temperature bin module 100. Since the large pulley 304 output shaft is fixedly connected with one of the eccentric shafts 307, the power on the large pulley can drive the eccentric shaft 307 to rotate, so that the circumferential oscillation table 301 also rotates around the center of the eccentric shaft 307, forming a circumferential oscillation track. Among them, the size ratio of the large pulley can improve the output torque on the large pulley.

[0061] In an embodiment of the present application, the first bin body 113 is an aluminum alloy, the second bin body 123 is an aluminum alloy, and the heat dissipation fins 126 are aluminum heat dissipation fins.

[0062] The aluminum alloy has good heat conduction performance and low cost.

[0063] In an embodiment of the present application, the diameter of the test tube hole 131 is 29.1 mm, and the depth is 103 mm. The test tube hole is used to place a 50 mL centrifuge tube.

[0064] Different sizes of sleeves can also be placed in the test tube hole to reduce the size and depth of the test tube hole to meet the centrifuge tubes smaller than 50 mL, such as 30 mL, 15 mL, 5 mL, etc. The sleeve is also made of aluminum alloy, so that heat can be transferred from the surrounding test tube hole to the inner sleeve, and then transferred to the centrifuge tube in the middle through the sleeve.

[0065] In an embodiment of the present application, the hole wall of the test tube hole has high adhesion with the tube wall of the centrifuge tube, high temperature transfer efficiency, small temperature fluctuation before and after the opening and closing of the bin door, and stable temperature.

[0066] In addition, although the exemplary embodiments have been described herein, the scope thereof includes any and all embodiments based on the present application with equivalent elements, modifications, omissions, combinations (for example, solutions of various embodiments are crossed), adaptations or changes.

[0067] The elements in the claims are to be construed broadly based on the language adopted in the claims, and are not limited to the examples described in the specification or during the implementation of the present application, and the examples are to be construed as non-exclusive. Therefore, the specification and examples are intended to be considered only as examples, and the true scope and spirit are indicated by the full scope of the claims and their equivalents.

[0068] The order of the steps in the present application is only exemplary and not limiting. Without affecting the implementation of the present application (without destroying the logical relationship between the required steps), the execution order of the steps can be adjusted, and the various embodiments obtained after the adjustment still fall within the scope of the present application.

[0069] The above description is intended to be illustrative, and not restrictive. For example, the above-described examples (or one or more aspects thereof) can be used in combination with each other. Other embodiments can be used in addition to those described specifically herein, by one of ordinary skill in the art upon reviewing the above description. Still further, in the specific embodiments described above, various features can be grouped together or divided up for the purpose of simplifying the present disclosure. This should not be interpreted as a requirement in any of the claims that the disclosed features be grouped together. Rather, the subject matter of the application encompasses any suitable claim. The scope of the application should be determined with reference to the appended claims and throughout the full scope of equivalents to which such claims are entitled.

Claims

1. A tissue processing device, characterized in that, include: The outer casing module, the constant temperature chamber module, and the oscillation module; The constant temperature chamber module is disposed above the oscillation module, and the constant temperature chamber module and the oscillation module are located in the outer shell module; The outer casing module includes: a control unit, a human-machine interface unit, a front door, and a housing; The constant temperature chamber module includes multiple temperature control chamber units and a chamber door for each temperature control chamber unit; wherein, each temperature control chamber unit is provided with a test tube hole, and the temperature control chamber units are stacked together; The control unit is used to control the temperature of each temperature-controlled chamber unit based on the temperature control command sent by the human-machine interaction unit; and to control the oscillation module to oscillate based on the oscillation command sent by the human-machine interaction unit, so as to drive each temperature-controlled chamber unit to oscillate.

2. The tissue processing apparatus as described in claim 1, characterized in that, Further includes: Angle adjustment module; The angle adjustment module is located in the outer shell module, the constant temperature chamber module is fixed on the angle adjustment module, and the angle adjustment module is fixed on the oscillation module. The control unit is used to control the movement of the angle adjustment module based on the angle adjustment command sent by the human-machine interaction unit, so as to change the tilt angle of each of the temperature control chamber units.

3. The tissue processing apparatus as described in claim 1, characterized in that, The plurality of temperature-controlled chamber units include: a heating chamber unit; The heating chamber unit includes: a first outer plate, a first heat insulation plate, a first chamber body, a heating plate, a first heat insulation layer, a first temperature sensor, and the test tube hole; The heating plate is provided around the outer perimeter of the first chamber. The first temperature sensor is provided at the bottom of the first chamber on the side away from the test tube opening. The heating plate, the first temperature sensor and the first chamber are wrapped in the first insulation layer. The first heat insulation plate is provided on the side of the first chamber, the heating plate and the first insulation layer near the test tube opening. The first outer plate is provided on the side of the first heat insulation plate near the test tube opening. The heating plate transfers the heat generated to the first chamber. The first temperature sensor contacts the first chamber and sends the collected temperature data to the control unit. The control unit sends the temperature data to the human-machine interface unit. The human-machine interface unit provides the temperature data to the user. The control unit controls the heating plate based on the temperature control command sent by the human-machine interface unit to increase the temperature of the heating chamber unit.

4. The tissue processing apparatus as described in claim 1, characterized in that, The plurality of temperature-controlled chamber units include: a room temperature chamber unit; The room temperature chamber unit includes: a second outer plate, a second heat insulation plate, a second chamber body, a heat-conducting block, a semiconductor cooling chip, heat dissipation fins, an axial fan, a second temperature sensor, a second insulation layer, and the test tube hole; the axial fan is installed on the outside of the heat dissipation fins. When the semiconductor cooling chip is forward-energized, the side of the semiconductor cooling chip that contacts the second chamber is the cold end, and the side that contacts the heat dissipation fins is the hot end. The cold end transfers the heat generated by the second chamber to the hot end, and the hot end transfers the heat to the heat dissipation fins. The axial fan blows air into the heat dissipation fins to transfer the heat from the heat dissipation fins to the air. When the semiconductor cooling chip is reverse-energized, the side of the semiconductor cooling chip that contacts the second chamber is the hot end, and the side that contacts the heat dissipation fins is the cold end. Heat is transferred from the hot end to the second chamber, and the cold end absorbs heat from the heat dissipation fins. The axial fan blows air into the heat dissipation fins so that the heat dissipation fins absorb heat from the air. The second temperature sensor contacts the second chamber and sends the collected temperature data to the control unit. The control unit sends the temperature data to the human-machine interface unit. The human-machine interface unit provides the temperature data to the user. The control unit controls the semiconductor cooling chip based on the temperature control command sent by the human-machine interface unit to adjust the temperature of the room temperature chamber unit.

5. The tissue processing apparatus as described in claim 4, characterized in that, The plurality of temperature-controlled chamber units also include: a refrigeration chamber unit; The refrigeration unit and the room temperature unit have the same structure. The control unit controls the semiconductor cooling chip in the refrigeration unit based on the temperature control command to adjust the temperature of the refrigeration unit. The temperature of the refrigeration unit is lower than the temperature of the room temperature unit.

6. The tissue processing apparatus as described in claim 2, characterized in that, The angle adjustment module includes: an upper base plate, an upper base plate handle, a lower base plate, a flip shaft, a linear slide rail, a rear connecting rod slider, a front connecting rod slider, a rear connecting rod, a front connecting rod, a pin, a pull rod, an electric push rod motor, a power assist spring, a horizontal limit position sensor, and a flip angle limit position sensor. The push rod of the electric push rod motor is connected to the pull rod via the pin; the pull rod is threadedly connected to the front connecting rod slider. When the control unit controls the push rod of the electric push rod motor to move forward based on the angle adjustment command, the pull rod moves forward synchronously, the front connecting rod slider also moves forward synchronously, the front connecting rod pulls the upper base plate to rotate horizontally around the flip axis, the connecting rod pushes the rear connecting rod slider to move backward, the assist spring is pulled open, until the upper base plate moves to a horizontal state, the horizontal limit position sensor is activated, and sends a first feedback signal to the control unit, the control unit controls the electric push rod motor to stop moving based on the first feedback signal; When the control unit controls the electric push rod motor to move backward based on the angle adjustment command, the pull rod moves backward synchronously, and the front connecting rod slider also moves backward synchronously. The front connecting rod pushes the upper base plate to rotate upward around the rotation axis, and the connecting rod pulls the rear connecting rod slider to move forward. The assist spring contracts until the upper base plate rotates to the maximum tilt angle. The rotation angle limit position sensor is activated and sends a second feedback signal to the control unit. Based on the second feedback signal, the control unit controls the electric push rod motor to stop moving.

7. The tissue processing apparatus as claimed in claim 1, characterized in that, The oscillation module includes: a circular oscillation table, a support frame, a small pulley, a large pulley, a belt, a rotary motor, and an eccentric shaft; The rotary motor flange is fixed on the support frame, the small pulley is connected to the output shaft of the rotary motor, and when the rotary motor rotates, the power is transmitted to the large pulley through the friction between the belt and the small pulley and the large pulley. The eccentric shaft is distributed between the circumferential oscillation table and the support frame, providing three-point support for the circumferential oscillation table to rotate circumferentially. The eccentric shaft is connected to the circumferential oscillation table and the support frame by a revolute joint. The output shaft of the large pulley is fixedly connected to one of the eccentric shafts. Based on the oscillation command, the control unit controls the rotary motor to rotate, thereby driving the circular oscillation table to move.

8. The tissue processing apparatus as described in claim 3, characterized in that, The first compartment is made of aluminum alloy.

9. The tissue processing apparatus as claimed in claim 4, characterized in that, The second chamber is made of aluminum alloy, and the heat dissipation fins are made of aluminum.

10. The tissue processing apparatus as claimed in claim 1, characterized in that, The test tube well has a diameter of 29.1 mm and a depth of 103 mm, and is used to hold a 50 mL centrifuge tube.