Mammary gland X-ray energy spectrum enhanced imaging system and method supporting synchronization of high-pressure injectors

Abstract

The invention provides a mammary gland X-ray energy spectrum enhanced imaging system and method supporting high-pressure injector synchronization. The system comprises a mammary gland X-ray system; a high pressure injector system; the synchronous control interfaces are respectively arranged in the mammary gland X-ray system and the high-pressure injector system and are used for providing standardized communication connection points; the injection communication module is used for realizing state synchronization and real-time data interaction between the mammary gland X-ray system and the high-pressure injector system; and the control module is used for receiving and analyzing the state information from the high-pressure injector system, automatically or manually triggering a breast positioning instruction and an X-ray photography instruction in an optimal window period after the contrast agent is injected, and ensuring that breast energy spectrum enhanced imaging is completed at an optimal physiological opportunity. By synchronizing the state of the high-pressure injector to the mammary gland X-ray system, synchronization of various states such as preparation, injection starting / suspending and injection finishing is achieved, a strict operation process is provided for mammary gland contrast enhancement photography, and an optimal image is output.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a mammography X-ray energy-spectral enhancement imaging system and method that supports synchronization with a high-pressure injector, and particularly to energy-spectral enhancement imaging of a mammography X-ray system and a high-pressure injector. Background Technology

[0002] X-ray-based mammography is increasingly widely used in the treatment of breast diseases. X-rays are short-wavelength, high-energy electromagnetic waves with penetrating power. When X-rays pass through certain materials, some of the electromagnetic waves are absorbed, and the intensity of the X-rays decreases exponentially. Different materials absorb X-rays differently, and the unabsorbed X-rays are received by a detector after passing through the object. The detector receives X-rays of varying intensities, converts them into digital signals, and sends these signals to a computer for processing and image reconstruction. This is the principle of digital mammography. The strength of the signal received by the detector depends on the density of the tissue within a cross-section of the breast. Tissues with higher density absorb more X-rays, resulting in a weaker signal, such as tumors and calcified tissues; tissues with lower density absorb less X-rays, resulting in a stronger signal, such as fatty tissues. The information received by the detector displays images of breast shadows of different densities. By comparing these shadow images and combining them with clinical experience, it is relatively easy to determine whether there are abnormalities in the breast tissue.

[0003] Full-field digital mammography (FFDM) is an important tool for current breast cancer screening. It provides high-resolution breast images in a very short time. However, its acquisition method has inherent limitations: tissue overlap. While it may be sufficient to detect abnormalities in screening, additional functional imaging techniques can offer significant diagnostic advantages for recalled women, as they can reveal atypical physiological processes.

[0004] Further diagnosis of breast cancer can be achieved using mammography with contrast enhancement, also known as energy-spectrum imaging. This is a novel, fully digital mammography technique based on X-ray attenuation and using iodine-based contrast agents. The contrast agent is injected to enhance the visibility of vascular structures or to visually represent the uptake of the contrast agent in the tissue. Understanding the distribution of neovascularization within the lesion of a malignant breast tumor allows for the detection of malignant lesions, and the analysis of the blood supply to the lesion can be performed within the mammography room.

[0005] Breast contrast-enhanced imaging requires the injection of a contrast agent. Because the uptake rate of the contrast agent differs between healthy breast tissue and tumor tissue, positioning and X-ray imaging must be performed within the optimal window of 2-6 minutes. Strict time control is required from the initiation of contrast agent injection to its completion, and then to breast positioning and imaging, in order to ensure the effectiveness of breast contrast-enhanced imaging. Summary of the Invention

[0006] To address the various shortcomings of existing technologies, this invention provides a breast X-ray energy-spectral enhancement imaging system and method that supports synchronization with a high-pressure injector. By synchronizing the status of the high-pressure injector to the breast X-ray system, it achieves synchronization of multiple states such as ready, start / pause injection, and injection completion, providing a strict workflow for breast contrast-enhanced imaging and outputting optimal images.

[0007] The present invention achieves the above objectives through the following technical solutions: A breast X-ray spectral enhancement imaging system supporting synchronization with a high-pressure injector includes: A mammography X-ray system is used to generate X-rays and receive X-rays after they pass through breast tissue, and convert the received X-rays into digital signals to reconstruct breast images; High-pressure injector system for injecting contrast agents into a patient via intravenous route; Synchronous control interfaces are located in both the mammography X-ray system and the high-pressure injector system, providing standardized communication connection points. The injection communication module establishes communication connections with the mammography X-ray system and the high-pressure injector system through a synchronous control interface, enabling status synchronization and real-time data exchange between the mammography X-ray system and the high-pressure injector system, including but not limited to the transmission of information such as injection rate, injection dose, injection time, ready status, in-injection status, and end-of-injection status. The control module, located within the mammography X-ray system, receives and analyzes status information from the high-pressure injector system. Based on the preset imaging process and algorithm, it automatically or manually triggers breast positioning and X-ray imaging commands within the optimal window period after contrast agent injection, ensuring that breast spectral enhancement imaging is completed at the optimal physiological time.

[0008] According to the present invention, a breast X-ray spectral enhancement imaging system supporting synchronization with a high-pressure injector is provided, wherein the injection communication module includes: The CAN bus module is used to implement CAN protocol-based communication functions and is used to connect to the CAN communication interfaces of the mammography X-ray system and the high-pressure injector system, respectively. Multiple first input / output ports and second input / output ports are used to receive and send control signals and status information. The first input / output ports interact with the CPU of the mammography X-ray system, and the second input / output ports interact with the CPU of the high-pressure injector system, thereby enabling the injection communication module to monitor the status of the high-pressure injector system and transmit control commands to the mammography X-ray system. Multiple logic control circuits are used to process signals from each input port and generate corresponding control signals to output ports according to preset logic.

[0009] A method for breast X-ray spectral enhancement imaging supporting high-pressure injector synchronization, the method employing the aforementioned breast X-ray spectral enhancement imaging system supporting high-pressure injector synchronization, includes the following steps: Initialize settings, start the mammography X-ray system and high-pressure injector system, and establish a communication connection with the injection communication module through their respective built-in synchronous control interfaces to ensure that the system is in an interactive state; Imaging parameters are set on the mammography system; simultaneously, injection parameters are set on the high-pressure injector system. The injection communication module receives real-time status information from the high-pressure injector system, including ready status, in-injection status, and estimated injection end time, and displays it on the mammography X-ray system interface; after confirming that the high-pressure injector system is ready, the imaging process is prepared to begin. According to the preset injection parameters, the high-pressure injector system is activated to deliver the contrast agent via intravenous route; simultaneously, the mammography system continuously receives and displays real-time status information during the injection process through the injection communication module. The control module of the mammography system automatically calculates and displays the optimal imaging window period after contrast agent injection based on the received injection end time information; within this window period, the operator performs breast positioning operations according to instructions. Based on the timing results, breast positioning and X-ray imaging were completed within the optimal window period after contrast agent injection; After breast positioning is completed within the optimal window period, the control module automatically or according to the operator's instructions triggers X-ray imaging, generates X-rays and receives X-rays after passing through breast tissue, and converts them into digital signals. The mammography X-ray system reconstructs images from the received digital signals, applies a preset image processing algorithm to optimize image quality, and obtains enhanced mammography images. The processed breast spectral enhancement images, along with related imaging parameters, injection parameters, and other information, are stored and displayed on the breast X-ray system interface.

[0010] According to the present invention, a method for mammography using high-pressure injector synchronization with energy-spectral contrast (ESG) includes the following steps when data interaction is performed using the CAN protocol: Initialize the ISI module of the high-pressure injector system and the mammography system to ensure that each device is in normal working condition; the ISI module is an interface module used to realize communication, control and data interaction between the high-pressure injector system and other medical devices. The communication object and node configuration interface allows for the configuration and authentication of communication objects and nodes that are permitted to interact with the system. Only authenticated communication objects and nodes can be added to the interactive list; unauthenticated objects and nodes cannot participate in subsequent data interaction processes. Configure the interaction permissions between the device software and the CAN communication interface, and set that only authorized operators or programs can perform configuration operations related to data interaction between the device software and the CAN interface to prevent unauthorized access from causing system failure or data leakage. The ISI module establishes a connection with the mammography X-ray system via a CAN bus module and uses the CAN protocol for data transmission; the ISI module acquires the status data of the high-pressure injector system in real time. The acquired status data is encapsulated and processed to generate a data frame according to the format specified by the CAN protocol, and then sent to the mammography X-ray system via the CAN bus. The mammography X-ray system receives the data frame, parses it, obtains the real-time status information of the syringe, and displays it on the system interface.

[0011] According to the present invention, a method for mammography with energy-spectral enhancement that supports synchronization with a high-pressure injector is provided. When it is necessary to configure or query the relevant parameters of the high-pressure injector system, the mammography system sends a read / write request instruction for the object dictionary to the ISI module via the CAN bus. The instruction clearly specifies the object dictionary entries to be operated and the corresponding read / write operation type. After receiving a read / write request command, the ISI module parses the command and accesses the object dictionary according to the command requirements. If it is a read operation, it reads the data of the corresponding entry from the object dictionary, encapsulates it according to the CAN protocol format, and returns it to the mammography X-ray system. If it is a write operation, it writes the new data carried in the command into the corresponding entry of the object dictionary, completing the parameter configuration update.

[0012] According to the present invention, a method for mammography with energy-spectral enhancement that supports synchronization with a high-pressure injector is provided, wherein an operation plan for the high-pressure injector system is preset on the mammography system. When the preset execution conditions are met, the mammography X-ray system sends control commands to the ISI module via the CAN bus. After receiving the commands, the ISI module controls the syringe to perform the corresponding operations according to the pre-set requirements, ensuring that the injection process meets the requirements of the examination procedure. Based on the examination process and requirements, and combined with the syringe status information obtained from the ISI module, the mammography X-ray system sends linkage control commands to the ISI module via the CAN bus. The ISI module coordinates the operation of the high-pressure injector system and the imaging action of the mammography system based on the received linkage control commands.

[0013] According to the present invention, a method for mammography with X-ray spectral enhancement that supports synchronization with a high-pressure injector is provided, wherein the required injection parameters are set in the high-pressure injector system; and contrast agent is prepared in the high-pressure injector system. Once the high-pressure injector system has completed setting the injection parameters and preparing the contrast agent, the injection communication module detects that the system is in a ready state. At this time, the internal circuit of the injection communication module causes the level of a specific input / output port IO10 to go low, thereby feeding back to the mammography X-ray system that the high-pressure injector system is in a ready-to-inject state and waiting for the mammography X-ray system to send further instructions. On the operating interface of the mammography system, verify the injection parameters set by the high-pressure injector system to check whether the parameters meet the requirements of this mammography examination and ensure that the injection process can cooperate with the imaging examination. After verifying that the parameters are correct, the mammography X-ray system sends an injection command to the injection communication module through its internal control logic. During the process of sending the injection command, the level of another set of specific input / output ports IO8 and IO2 of the injection communication module simultaneously goes low, which serves as a clear injection start signal to be transmitted to the high-pressure injector system. The high-pressure injector system continuously monitors the status of the input and output ports of the injection communication module. When it detects that the input and output ports IO8 and IO2 have gone low, it recognizes this as a valid injection command from the mammography system and then starts the injection program to complete the contrast agent injection operation in conjunction with the mammography examination according to the preset injection parameters.

[0014] According to the present invention, a method for mammography with X-ray energy-spectral enhancement that supports synchronization with a high-pressure injector is provided. During the contrast agent injection process, the high-pressure injector system generates an injection command and controls the level of specific input / output ports IO5 and IO11 of the injection communication module to go low simultaneously through internal circuitry. This is sent to the mammography X-ray system as an injection command. After receiving the command, the mammography X-ray system converts it into recognizable information and displays it on the operation interface. At the same time, it starts an internal timer to record the time information of the injection process. After the contrast agent injection is completed, the high-pressure injector system generates an injection completion command and simultaneously lowers the level of another set of specific input / output ports IO6 and IO12 of the injection communication module, transmitting the injection completion command to the mammography X-ray system. Before the exposure countdown ends, the mammography system is operated; when the exposure countdown ends, specific operation commands are executed on the operation interface of the mammography system to trigger the mammography system to perform energy-spectrum enhanced imaging; the mammography system completes low-energy and high-energy X-ray exposures in sequence according to the preset program to obtain mammary image information at different energies.

[0015] According to the present invention, a method for breast X-ray energy spectrum enhancement imaging that supports synchronization with a high-pressure injector is provided, which performs reconstruction and subtraction post-processing operations on the acquired breast energy spectrum image data. Based on the OpenGL rendering module, the post-processed dual-energy subtraction image data is rendered in real time, converting the image data into a graphic image that can be intuitively presented on the display device; then, the rendered image is output and displayed in real time on the operating interface of the mammography system or a designated display device. The DICOMEditor software tool or related function library is invoked to parse the preset DICOM template; After the parameters are filled in, the rendered dual-energy subtraction image data is integrated with the DICOM template with the parameters filled in, and a complete dual-energy subtraction DICOM image file is generated according to the DICOM file format specifications.

[0016] According to the present invention, a method for breast X-ray spectral enhancement imaging supporting synchronization with a high-pressure injector is provided. The acquired breast spectral image data is first subjected to noise suppression and correction processing. A median filtering algorithm is used to suppress noise in the image. The median filtering formula is as follows:

[0017] in, f ( s , t ) is the original image at coordinates ( s , t The pixel value at () S xy For coordinates ( x , y The filtering window is centered on ) g ( x , y ) represents the image after median filtering at coordinates ( x , y The pixel value at () Based on the physical model of energy spectrum imaging, the expectation-maximum EM algorithm is used to reconstruct image data from low-energy and high-energy exposures; let the observed low-energy and high-energy image data be respectively... Y L and Y HThe distribution of the hidden breast tissue attenuation coefficient is as follows: X Then the iterative formula for the EM algorithm is:

[0018] in, A and B The system matrices for low-energy and high-energy imaging systems, respectively, describe the mapping relationship from tissue attenuation coefficients to observed images; N and M These represent the number of pixels in the low-energy and high-energy images, respectively. k This represents the number of iterations. The reconstructed low-energy image IL and high-energy images IH The subtraction operation is represented as:

[0019] in, I sub The image after subtraction. ks This is the subtraction factor.

[0020] Therefore, compared with the prior art, the breast X-ray energy spectrum enhancement imaging system and method supporting high-pressure injector synchronization proposed in this invention have the following beneficial effects: 1. This invention achieves synchronized control of the high-pressure injector and the mammography system, ensuring that the contrast agent is injected, the breast is positioned, and X-ray imaging is completed within the optimal window period (2-6 minutes). This significantly improves the contrast-enhanced imaging effect of the breast, making the contrast between high-density lesions such as tumors and calcified tissues and the surrounding low-density tissues (such as fat) more vivid, thereby improving image clarity and detail. Based on these high-quality images, doctors can more accurately determine whether there are abnormalities in breast tissue, improving the early detection rate and diagnostic accuracy of diseases such as breast cancer.

[0021] 2. This invention employs a message-driven and data-interactive approach to automate the operation of the high-pressure injector during imaging examinations. This eliminates the need for technicians to manually operate the injector or precisely time injections and imaging, significantly reducing their workload. The automated process minimizes errors caused by human factors, such as missing the optimal imaging window due to improper timing, thus improving the consistency and reliability of the examination.

[0022] 3. Through closed-loop control and automated collaborative working mechanisms, this invention significantly improves the examination efficiency of breast X-ray spectral enhancement imaging, enabling faster completion of the entire process from contrast agent injection to image acquisition, reducing patient waiting time, and improving diagnostic and treatment efficiency. Simultaneously, the automated examination process reduces repetitive examinations caused by human error, further optimizing the utilization of medical resources.

[0023] 4. The system design of this invention has high compatibility, not limiting the brand and model of the high-pressure injector. As long as the communication requirements of the synchronization interface are met, it can be connected and used. This allows the invention to be widely applied in different medical institutions and equipment environments, reducing users' procurement costs and lowering the barrier to entry. Furthermore, since no similar solution for synchronizing breast X-ray spectral enhancement imaging with a high-pressure injector has been found on the market, this invention has significant market expansion advantages and is expected to become one of the mainstream technologies in the field of breast imaging in the future.

[0024] 5. This invention supports multiple positioning and imaging positions, enabling comprehensive capture of breast tissue information from different angles and layers. This is particularly important for the diagnosis of complex cases, helping doctors to more accurately determine the nature and extent of lesions. Simultaneously, multi-position imaging improves the flexibility and adaptability of the examination, meeting the clinical needs of different patients.

[0025] The present invention will now be described in further detail with reference to the accompanying drawings and specific embodiments. Attached Figure Description

[0026] Figure 1 This is a simplified workflow diagram of an embodiment of a breast X-ray energy spectral enhancement imaging system that supports synchronization with a high-pressure injector according to the present invention.

[0027] Figure 2 This is a schematic diagram of an embodiment of a breast X-ray energy spectrum enhancement imaging system that supports synchronization with a high-pressure injector according to the present invention.

[0028] Figure 3 This is a diagram showing the linkage information interface between the high-pressure injector system and the mammography system in an embodiment of the present invention, which supports synchronization of a high-pressure injector with a mammography X-ray energy spectrum enhancement imaging system.

[0029] Figure 4 This is a schematic diagram illustrating the principle of synchronous control between the high-pressure injector system and the mammography system in an embodiment of a mammography X-ray energy spectrum enhancement imaging system supporting synchronization with a high-pressure injector according to the present invention.

[0030] Figure 5 This is a circuit diagram of the high-pressure injector system, the mammary X-ray system, and the injection communication module in an embodiment of a mammary X-ray energy spectrum enhancement imaging system supporting synchronization with a high-pressure injector according to the present invention. Detailed Implementation

[0031] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this invention. All other embodiments obtained by those skilled in the art based on the embodiments of this invention without creative effort are within the scope of protection of this invention.

[0032] In this document, the term "embodiment" means that a particular feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a separate or alternative embodiment mutually exclusive with other embodiments. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.

[0033] Enhanced X-ray imaging of the breast is based on X-ray attenuation. Different substances absorb X-rays differently; unabsorbed X-rays pass through the object and are received by a detector. The detector receives X-rays of varying intensities and converts them into digital signals. A single patient position requires two consecutive exposures, one low-energy and one high-energy, to obtain low-energy and high-energy image information. This information is further uploaded to an image processing workstation. Based on the difference in absorption rates of iodine contrast agents to high and low-energy X-rays, subtraction processing is performed on the low-energy and high-energy images to remove normal tissue from the breast tissue, resulting in a subtracted image containing only the lesion.

[0034] A high-pressure injector delivers iodine contrast agent intravenously to the patient requiring contrast-enhanced mammography. The main control panel allows for setting injection parameters and configuring the system. The touchscreen on the main unit enables functions such as drug aspiration, air release, trial injection, and injection. The working principle is as follows: a microprocessor chip sends control signals to rotate a motor, which in turn drives a lead screw to convert rotational motion into linear motion, pushing the piston of the injector to deliver the drug solution into the patient. This achieves high-precision, stable, and pulsation-free liquid delivery for contrast enhancement.

[0035] The clinical workflow for contrast-enhanced spectral imaging begins with the injection of iodine contrast agent using a high-pressure injector. At the time of injection, the breast is not yet compressed to allow for normal tissue perfusion; the flow of contrast agent into the breast should not be obstructed. After waiting 2 minutes, breast compression can begin, and the first positional contrast-enhanced exposure can be performed. This process is repeated, typically requiring 4-6 positions for imaging. To minimize absorption of the iodine solution by normal tissue, the imaging should be completed within a 2-6 minute timeframe whenever possible. Figure 1 As shown.

[0036] An embodiment of a breast X-ray spectral enhancement imaging system supporting synchronization with a high-pressure injector See Figures 2 to 5 This embodiment provides a breast X-ray energy-spectral enhancement imaging system that supports synchronization with a high-pressure injector, comprising: A mammography X-ray system is used to generate X-rays and receive X-rays after they pass through breast tissue, and convert the received X-rays into digital signals to reconstruct breast images; High-pressure injector system for injecting contrast agents into a patient via intravenous route; Synchronous control interfaces are located in both the mammography X-ray system and the high-pressure injector system, providing standardized communication connection points. The injection communication module establishes communication connections with the mammography X-ray system and the high-pressure injector system through a synchronous control interface, enabling status synchronization and real-time data exchange between the mammography X-ray system and the high-pressure injector system, including but not limited to the transmission of information such as injection rate, injection dose, injection time, ready status, in-injection status, and end-of-injection status. The control module, located within the mammography X-ray system, receives and analyzes status information from the high-pressure injector system. Based on the preset imaging process and algorithm, it automatically or manually triggers breast positioning and X-ray imaging commands within the optimal window period after contrast agent injection, ensuring that breast spectral enhancement imaging is completed at the optimal physiological time.

[0037] like Figure 2 As shown, the X-ray tube module includes a high-voltage generator section and an X-ray tube module. The high-voltage generator section generates a high-frequency pulse voltage, which is rectified and applied to the X-ray tube, causing the tube to produce X-rays. The collimator module confines the X-ray field of view to a specified range, preventing the patient from receiving additional X-ray exposure. The compression plate module receives motion control commands and controls the up-and-down movement of the compression plate to compress the breast and obtain optimal breast imaging results. The exposure control module implements exposure control, controlling the high-voltage module and the detector plate. The detector plate module receives X-rays and converts them into digital image information. The image processing module obtains the image information from the detector plate, and then performs image optimization processing and display, as well as image analysis and sharing. The injection communication module is responsible for receiving the current status of the high-voltage injector and synchronously displaying the received information to the breast X-ray system. The high-voltage injector includes an injection control module and an injection module, which can inject contrast agents into the patient's breast tissue.

[0038] In this embodiment, the mammography system has a high-pressure injector connection interface. This interface connects to the high-pressure injector via CAN, allowing the high-pressure injector to synchronize information such as injection rate, dosage, time, readiness status, in-injection status, and termination status to the mammography system (e.g., [missing information]). Figure 3 (As shown). After the contrast agent injection is completed, the high-pressure injector will automatically synchronize the time to the operating interface of the mammography system. After the technician in charge of the exposure waits for 2 minutes, the patient's breast will be positioned and exposed within 2-6 minutes, which can strictly control the imaging time after the contrast agent is injected.

[0039] like Figure 4 As shown, the mammography X-ray system includes: an X-ray tube for generating X-rays; a high-pressure section connected to the X-ray tube for providing the high pressure required for X-ray generation; an exposure control module including a processor 1 for controlling exposure parameters and procedures; the exposure control module is also connected to a communication module for communication with external devices; a compressor motion control module including a processor 2 for controlling the movement of the compressor plate to adjust the position of the breast; this module is also connected to the communication module 2 for information exchange; the high-pressure injector system includes: an injection module for storing contrast agent and injecting the contrast agent into the patient via intravenous route; an injection motion drive connected to the injection module for providing injection power; and a processor for controlling injection parameters and procedures.

[0040] The injection communication module is used to establish a communication connection between the mammography X-ray system and the high-pressure injector, enabling status synchronization and real-time data interaction between the two. It receives injection status information from the high-pressure injector, including but not limited to injection rate, injection dose, injection time, ready status, in-injection status, and end-of-injection status, and transmits this information to the exposure control module and the compressor motion control module of the mammography X-ray system. It also receives control commands from the mammography X-ray system and transmits these commands to the high-pressure injector to achieve coordinated control of the injection process and the X-ray imaging process. Therefore, by using an injection communication module to achieve close cooperation between the mammography X-ray system and the high-pressure injector, within the optimal window period after contrast agent injection, the exposure control module and the compression plate movement control module of the mammography X-ray system automatically or manually trigger the corresponding exposure and compression plate movement operations based on the received injection status information, ensuring that mammography is completed at the optimal physiological time.

[0041] In this embodiment, the injection communication module includes: The CAN bus module is used to implement CAN protocol-based communication functions and is used to connect to the CAN communication interfaces of the mammography X-ray system and the high-pressure injector system, respectively. Multiple primary and secondary input / output ports, such as IO1-IO12, are used to receive and send control signals and status information. For example, IO3 receives the connection status signal of the high-pressure injector, IO4 receives the ready status signal, IO5 receives the injection in progress status signal, and IO6 receives the injection completed and ready-to-expose status signal. Simultaneously, IO7 can be used to send a cancel ready command, and IO8 can be used to send an injection start command. Through these I / O interfaces, precise monitoring of different states of the high-pressure injector and flexible control of the injection process are achieved.

[0042] The first input / output port interacts with the CPU of the mammography X-ray system, and the second input / output port interacts with the CPU of the high-pressure injector system, thereby enabling the injection communication module to transmit status monitoring and control commands to the high-pressure injector system and the mammography X-ray system. Multiple logic control circuits process signals from each input port and generate corresponding control signals to output ports based on preset logic. For example, when receiving status signals such as "connected," "ready," "injecting," or "injection complete, ready for exposure" from the high-pressure injector, the logic control unit generates control commands such as "cancel readiness" or "start injection" through logical operations and judgments based on these signals and relevant signals received from the mammography X-ray system. This coordinates the operating timing of the high-pressure injector and the mammography X-ray system, ensuring precise coordination between the injection process and the X-ray exposure process.

[0043] The injection communication module can process and analyze various received signals in real time, and dynamically adjust the control strategy according to the working status and requirements of the high-pressure injector and the mammography system. For example, after the high-pressure injector completes the injection and sends a "injection complete, exposure permitted" signal, the injection communication module promptly sends a control signal to the mammography system to allow exposure, achieving seamless connection between injection and exposure operations and improving the efficiency and accuracy of mammography examinations.

[0044] In summary, through the aforementioned internal structure and connection relationships, this injection communication module can effectively realize information exchange and collaborative control between the high-pressure injector and the mammography X-ray system, ensuring the precise execution of injection operations and good coordination with X-ray exposure during mammography X-ray examinations.

[0045] An embodiment of a method for mammography using X-ray energy-spectral enhancement imaging with high-pressure injector synchronization. This embodiment provides a method for mammography using X-ray energy-spectral contrast imaging that supports synchronization with a high-pressure injector. The method employs the aforementioned mammography system that supports synchronization with a high-pressure injector and includes the following steps: Initialize the settings, start the mammography X-ray system and the high-pressure injector system, and establish a communication connection with the injection communication module through their respective built-in synchronous control interfaces to ensure that the system is in an interactive state; the definition of the synchronous control interface is shown in Table 1.

[0046] Imaging parameters are set on the mammography system; simultaneously, injection parameters are set on the high-pressure injector system. The injection communication module receives real-time status information from the high-pressure injector system, including ready status, in-injection status, and estimated injection end time, and displays it on the mammography X-ray system interface; after confirming that the high-pressure injector system is ready, the imaging process is prepared to begin. According to the preset injection parameters, the high-pressure injector system is activated to deliver the contrast agent via intravenous route; simultaneously, the mammography system continuously receives and displays real-time status information during the injection process through the injection communication module. The control module of the mammography system automatically calculates and displays the optimal imaging window period after contrast agent injection based on the received injection end time information; within this window period, the operator performs breast positioning operations according to instructions. Based on the timing results, breast positioning and X-ray imaging were completed within the optimal window period after contrast agent injection; After breast positioning is completed within the optimal window period, the control module automatically or according to the operator's instructions triggers X-ray imaging, generates X-rays and receives X-rays after passing through breast tissue, and converts them into digital signals. The mammography X-ray system reconstructs images from the received digital signals, applies a preset image processing algorithm to optimize image quality, and obtains enhanced mammography images. The processed breast spectral enhancement images, along with related imaging parameters, injection parameters, and other information, are stored and displayed on the breast X-ray system interface.

[0047] Table 1: Pin Definitions of the 9-Pin Aviation Head Interface for Mammography X-rays

[0048] In this embodiment, when using the CAN protocol for data interaction, the following steps are included: Initialize the ISI module of the high-pressure injector system and the mammography system to ensure that each device is in normal working condition; the ISI module is an interface module used to realize communication, control and data interaction between the high-pressure injector system and other medical devices. The communication object and node configuration interface allows for the configuration and authentication of communication objects and nodes that are permitted to interact with the system. Only authenticated communication objects and nodes can be added to the interactive list; unauthenticated objects and nodes cannot participate in subsequent data interaction processes. Configure the interaction permissions between the device software and the CAN communication interface, and set that only authorized operators or programs can perform configuration operations related to data interaction between the device software and the CAN interface to prevent unauthorized access from causing system failure or data leakage. The ISI module establishes a connection with the mammography X-ray system via a CAN bus module and uses the CAN protocol for data transmission; the ISI module acquires the status data of the high-pressure injector system in real time. The acquired status data is encapsulated and processed to generate a data frame according to the format specified by the CAN protocol, and then sent to the mammography X-ray system via the CAN bus. After receiving the data frame, the mammography X-ray system parses and processes it to obtain the real-time status information of the syringe, and displays it on the system interface so that the operator can understand the working status of the syringe in real time.

[0049] When it is necessary to configure or query the relevant parameters of the high-pressure injector system, the mammography X-ray system sends a read / write request command for the object dictionary to the ISI module via the CAN bus. The command clearly specifies the object dictionary entry to be operated on and the corresponding read / write operation type. After receiving a read / write request command, the ISI module parses the command and accesses the object dictionary according to the command requirements. If it is a read operation, it reads the data of the corresponding entry from the object dictionary, encapsulates it according to the CAN protocol format, and returns it to the mammography X-ray system. If it is a write operation, it writes the new data carried in the command into the corresponding entry of the object dictionary, completing the parameter configuration update.

[0050] An operational plan for a high-pressure injector system is pre-set on the mammography system. The plan defines in detail the injection parameters, injection time points, and coordination with other examination actions of the injector in different examination scenarios. When the preset execution conditions are met, the mammography X-ray system sends control commands to the ISI module via the CAN bus. After receiving the commands, the ISI module controls the syringe to perform corresponding operations according to the preset requirements, such as starting injection, adjusting injection rate, and stopping injection, to ensure that the injection process meets the requirements of the examination procedure. Based on its own examination procedures and needs, and combined with the syringe status information obtained from the ISI module, the mammography X-ray system sends linkage control commands to the ISI module via the CAN bus.

[0051] The ISI module coordinates the operation of the high-pressure injector system with the exposure and scanning actions of the mammography system based on received linkage control commands. For example, it controls the mammography system to perform exposure imaging at the optimal time after contrast agent injection, ensuring that high-quality mammography images are obtained under appropriate physiological conditions, thereby improving diagnostic accuracy.

[0052] Set the required injection parameters in the high-pressure injector system; at the same time, prepare the contrast agent in the high-pressure injector system. Once the high-pressure injector system has completed setting the injection parameters and preparing the contrast agent, the injection communication module detects that the system is in a ready state. At this time, the internal circuit of the injection communication module causes the level of a specific input / output port IO10 to go low, thereby feeding back to the mammography X-ray system that the high-pressure injector system is in a ready-to-inject state and waiting for the mammography X-ray system to send further instructions. On the operating interface of the mammography system, verify the injection parameters set by the high-pressure injector system to check whether the parameters meet the requirements of this mammography examination and ensure that the injection process can cooperate with the imaging examination. After verifying that the parameters are correct, the mammography X-ray system sends an injection command to the injection communication module through its internal control logic. During the process of sending the injection command, the level of another set of specific input / output ports IO8 and IO2 of the injection communication module simultaneously goes low, which serves as a clear injection start signal to be transmitted to the high-pressure injector system. The high-pressure injector system continuously monitors the status of the input and output ports of the injection communication module. When it detects that the input and output ports IO8 and IO2 have gone low, it recognizes this as a valid injection command from the mammography system and then starts the injection program to complete the contrast agent injection operation in conjunction with the mammography examination according to the preset injection parameters.

[0053] During contrast agent injection, the high-pressure injector system generates an injection command and controls the level of specific input / output ports IO5 and IO11 of the injection communication module to go low simultaneously via internal circuitry. This is sent to the mammography X-ray system as an injection command. Upon receiving the command, the mammography X-ray system converts it into recognizable information and displays it on the operating interface. At the same time, it starts an internal timer to accurately record the time information of the injection process. After the contrast agent injection is completed, the high-pressure injector system generates an injection completion command and simultaneously lowers the voltage levels of another set of specific input / output ports IO6 and IO12 of the injection communication module, transmitting the injection completion instruction to the mammography system. Upon receiving this instruction, the mammography system displays a clear "Injection Complete" message on the operating interface, informing the operator that the injection process is complete.

[0054] Before the exposure countdown ends, the mammography system is manually operated to adjust the patient's position and apply sufficient breast compression to ensure that the breast is in the optimal imaging position and condition, thus making full preparation for the subsequent exposure imaging. When the exposure timer of the mammography system reaches 2 minutes, the operator executes a specific operation command on the operating interface of the mammography system to trigger the mammography system to perform energy-spectrum enhanced imaging; the mammography system completes low-energy and high-energy X-ray exposures in sequence according to the preset program to obtain breast image information at different energies.

[0055] After completing the low-energy and high-energy exposures, the mammography X-ray system automatically records the time of this exposure operation and marks it as the "Acquisition 1" time, accurately recording the time nodes of the imaging process to provide a time basis for subsequent image analysis and diagnosis.

[0056] Based on actual clinical needs, the operator continues to operate the mammography system, arranging and taking images in other positions, generally performing 4-6 imaging operations. After each exposure is completed, the mammography system automatically records the time between the exposure and the start of the contrast agent injection, forming a complete time record sequence. This allows for a comprehensive and accurate analysis of the uptake and distribution of the contrast agent in the breast tissue, providing detailed temporal information for disease diagnosis.

[0057] For the acquired breast spectral imaging data, a specific algorithm is used for reconstruction and post-subtraction processing. The reconstruction process is based on the physical principles and mathematical models of spectral imaging, optimizing the image data acquired from low-energy and high-energy exposures to improve image quality, contrast, and resolution. Post-subtraction processing involves pixel-level calculations on the low-energy and high-energy images to eliminate the influence of background and irrelevant tissue, highlighting the lesions and contrast agent distribution within the breast, and generating clear dual-energy subtraction image data.

[0058] Based on the OpenGL rendering module, post-processed dual-energy subtraction angiography image data is rendered in real time. The OpenGL rendering module utilizes its powerful graphics processing capabilities to perform operations such as color mapping, lighting simulation, and view transformation according to the characteristics of the image data and display requirements, converting the image data into a graphical image that can be intuitively displayed on a display device. Then, the rendered image is output in real time and displayed on the operating interface of the mammography system or a designated display device for operators to observe and analyze in real time.

[0059] The DICOMEditor software tool or related function library is invoked to parse the preset DICOM template. DICOMEditor can accurately identify each field and structure in the DICOM template, understand its data format and semantics, and accurately fill in the examination-related parameters such as the current body position exposure time, patient information, examination equipment information, and injection parameters into the preset DICOM custom fields according to the DICOM standard, ensuring the completeness and accuracy of the information.

[0060] After the parameters are entered, the rendered dual-energy subtraction angiography (DSA) image data is integrated with the DICOM template with the entered parameters. Following the DICOM file format specifications, a complete DSA DICOM image file is generated. This file contains all the key information from the breast spectral imaging examination, including image data, examination parameters, and patient information. It meets the standard requirements for medical image storage and transmission, facilitating subsequent storage, archiving, transmission, and sharing, and providing a reliable data foundation for long-term preservation of medical images and remote diagnosis.

[0061] For the acquired breast spectral image data, noise suppression and correction processing is first performed. Median filtering is used to suppress noise in the images; the median filtering formula is as follows:

[0062] in, f ( s , t ) is the original image at coordinates ( s , t The pixel value at () S xy For coordinates ( x , y The filtering window is centered on ) g ( x , y ) represents the image after median filtering at coordinates ( x , y The pixel value at () is used. Median filtering is applied to remove random noise from the image, improving the signal-to-noise ratio. Next, geometric and intensity corrections are performed to eliminate image distortion and uneven brightness caused by equipment errors, patient movement, and other factors during imaging.

[0063] Based on a physical model of energy spectrum imaging, the expectation-maximization (EM) algorithm is used to reconstruct image data from low-energy and high-energy exposures. Let the observed low-energy and high-energy image data be respectively... YL and YH The distribution of the hidden breast tissue attenuation coefficient is as follows: X Then the iterative formula for the EM algorithm is:

[0064] in, A and B The system matrices for low-energy and high-energy imaging systems, respectively, describe the mapping relationship from tissue attenuation coefficients to observed images; N and M These represent the number of pixels in the low-energy and high-energy images, respectively. k This represents the number of iterations. It is updated through continuous iteration. X This makes the reconstructed image closer to the actual attenuation coefficient distribution of breast tissue, improving the accuracy and resolution of the image.

[0065] The reconstructed low-energy image IL and high-energy images IH Subtraction is performed to eliminate the influence of background and irrelevant tissue, highlighting the lesions and contrast agent distribution within the breast. The subtraction formula is:

[0066] in, I sub The image after subtraction. ks The subtraction factor is determined based on the intensity ratio of low-energy and high-energy images and the energy spectrum characteristics of the contrast agent, and is adjusted... ks This can make the subtraction image better display the lesion area and improve the detection rate of lesions.

[0067] Further optimization processing is performed on the subtracted image, including contrast enhancement and edge sharpening. Histogram equalization is used for contrast enhancement, which works by redistributing the grayscale values ​​of image pixels to make the image's grayscale histogram more uniform, thereby enhancing image contrast. For edge sharpening, the Laplacian operator is used for edge detection and enhancement. The Laplacian operator formula is:

[0068] In practical applications, the method provided in this embodiment specifically includes the following steps: (1) Connect the synchronous control interface of the mammography X-ray system. The interface is defined as shown in Table 1.

[0069] (2) After the main unit of the mammary X-ray system is powered on and initialized, select the high-pressure injector to enhance the imaging mode and wait to receive the connection request sent by the 320 injector communication module.

[0070] (3) After the host of the high-pressure injector system is powered on and initialized, the injection communication module IO3 goes low and IO9 goes low, indicating that the mammography X-ray system and the high-pressure injector system are successfully connected.

[0071] (4) The workstation periodically queries the current settings parameters of the high-pressure injector, such as injection rate, injection dose, and contrast agent concentration, through the serial port protocol and according to the serial port instruction set defined with the lower-level machine. It also parses the data frames returned by the injector and displays the parameters in real time on the high-pressure injector and the acquisition status interface.

[0072] (5) After the high-pressure injector system sets the injection parameters and prepares the contrast agent, the injection communication mode IO4 and IO10 decrease. The operator confirms that the high-pressure injector is ready and waits for the mammography X-ray system to issue instructions.

[0073] (6) After the operator verifies that the parameters are correct, the mammary X-ray system sends an injection command. The injection communication mode IO8 goes low, IO2 goes low, and the high-pressure injector system starts injection.

[0074] (7) If the operator discovers a problem / abnormality in the parameter settings, the mammography X-ray system will send a "cancel ready" signal, the injection communication module IO7 will go low, IO1 will also go low, the high-pressure injector system will cancel the ready status, and high-pressure injector injection will be prohibited. After verification, the ready signal will be sent again.

[0075] (8) During the injection process, the high-pressure injector system sends an injection command, the injection communication mode IO5 goes low, IO11 also goes low, the mammography X-ray system receives the action command and displays it on the interface, and starts timing.

[0076] (9) After the injection is completed, the high-pressure injector system sends an injection completion command, the injection communication mode IO6 goes low, IO12 also goes low, and the interface of the mammography X-ray system displays "Injection completed".

[0077] (10) Two minutes before the exposure countdown ends, operate the mammography system to adjust the body position and apply sufficient pressure to prepare for the exposure.

[0078] (11) When the exposure timer of the mammography system reaches 2 minutes, the operator operates the mammography system to perform energy spectrum enhancement photography to complete the low-energy and high-energy exposure.

[0079] (12) After exposure is completed, the mammography X-ray system records the time of “Acquisition 1”.

[0080] (13) Depending on clinical needs, other positions and imaging are then performed. Generally, 4-6 positions are used for imaging. The mammography system records the time between each exposure and the injection of contrast agent.

[0081] (14) Perform algorithmic reconstruction and subtraction post-processing on the acquired energy spectrum image data, and perform real-time image rendering and output display based on the OpenGL rendering module. Call DICOMEditor to parse the DICOM template, fill in the inspection parameters such as the current body position and exposure time into the preset DICOM custom fields, and generate a complete dual-energy subtraction DICOM image file for storage and archiving.

[0082] As can be seen from the above steps, this invention effectively realizes the application of high-pressure injectors in mammography X-ray systems, enabling automated collaborative operation of high-pressure injectors during the imaging examination process. This significantly reduces the workload of examination technicians, minimizes errors caused by manual injection and time differences, prevents missed optimal imaging windows, and improves work efficiency. Simultaneously, it enables the archiving of contrast agent injection records, filling a crucial gap in radiological image quality control, standardizing the imaging examination process, and improving examination quality.

[0083] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0084] The above embodiments are merely preferred embodiments of the present invention and should not be construed as limiting the scope of protection of the present invention. Any non-substantial changes and substitutions made by those skilled in the art based on the present invention shall fall within the scope of protection claimed by the present invention.

Claims

1. A breast x-ray spectrum enhanced imaging system supporting high voltage injector synchronization, comprising: The system comprises: a breast X-ray system for generating X-rays and receiving X-rays after passing through breast tissue, converting the received X-rays into digital signals to reconstruct a breast image; a high-pressure injector system for injecting contrast agent into a patient's body through an intravenous route; a synchronous control interface provided in the breast X-ray system and the high-pressure injector system, respectively, for providing a standardized communication connection point an injection communication module for establishing communication connection with the breast X-ray system and the high-pressure injector system through the synchronous control interface, realizing state synchronization and real-time data interaction between the breast X-ray system and the high-pressure injector system, including but not limited to injection rate, injection dose, injection time, ready state, injection state and end injection state information transmission; a control module located in the breast X-ray system for receiving and analyzing state information from the high-pressure injector system, automatically or manually triggering breast positioning instructions and X-ray photography instructions in the best window period after contrast agent injection according to a preset imaging process and algorithm, ensuring completion of breast spectral enhanced imaging at the best physiological time.

2. The system of claim 1, wherein, The injection communication module comprises: a CAN bus module for realizing CAN protocol-based communication function, respectively connected with the CAN communication interfaces of the breast X-ray system and the high-pressure injector system; a plurality of first input / output ports and second input / output ports for receiving and sending control signals and state information; wherein the first input / output ports interact with the CPU of the breast X-ray system, and the second input / output ports interact with the CPU of the high-pressure injector system, thereby realizing state monitoring and control instruction transmission of the injection communication module to the high-pressure injector system and the breast X-ray system, a plurality of logic control circuits for processing signals from each input port and generating corresponding control signals according to a preset logic and outputting to the output port.

3. A method of breast x-ray spectrum enhanced imaging supporting high voltage injector synchronization, characterized in that, The method adopts the breast X-ray spectral enhanced imaging system supporting high-pressure injector synchronization as claimed in claim 1 or 2, comprising the following steps: initialization setting, starting the breast X-ray system and the high-pressure injector system, establishing communication connection with the injection communication module through the respective built-in synchronous control interface, ensuring that the system is in an interactive state; setting imaging parameters on the breast X-ray system; at the same time, setting injection parameters on the high-pressure injector system; real-time receiving of state information of the high-pressure injector system through the injection communication module, including ready state, injection state and estimated end injection time, and displaying on the breast X-ray system interface; after confirming that the high-pressure injector system is in the ready state, preparing to start the imaging process; starting the high-pressure injector system to output contrast agent through an intravenous route according to the preset injection parameters; at the same time, the breast X-ray system continuously receives and displays real-time state information during the injection process through the injection communication module the control module of the breast X-ray system automatically calculates and displays the best imaging window period after the contrast agent injection according to the received injection end time information; within the window period, the operator performs breast positioning operation according to the instructions; According to the timing result, breast positioning and X-ray photography are completed in the optimal window period after the injection of the contrast agent; After the breast positioning is completed in the optimal window period, the control module automatically or according to the instruction of the operator triggers the X-ray photography, generates X-rays and receives the X-rays after passing through the breast tissue, and converts the X-rays into digital signals; The breast X-ray system reconstructs the received digital signals, optimizes the image quality by applying a preset image processing algorithm, and obtains a breast spectral enhancement image; The processed breast spectral enhancement image and related imaging parameters, injection parameters and other information are stored, and the imaging results are displayed on the interface of the breast X-ray system.

4. The method of claim 3, wherein, When data interaction is performed by using the CAN protocol, the following steps are included: The ISI module of the high-pressure injector system and the breast X-ray system are initialized and set to ensure that the devices are in a normal working state; the ISI module is an interface module for realizing communication, control and data interaction between the high-pressure injector system and other medical devices; The communication objects and nodes allowed to interact with the system are configured and authenticated through the communication object and node configuration interface; only the authenticated communication objects and nodes can be added to the interactive list, and the unauthenticated objects and nodes cannot participate in the subsequent data interaction process; The interaction authority of the device software and the CAN communication interface is authorized and configured, and it is set that only the authorized operators or programs can perform configuration operations related to data interaction of the device software and the CAN interface, so as to prevent system failure or data leakage caused by unauthorized access; The ISI module and the breast X-ray system are connected through the CAN bus module, and data transmission is performed by using the CAN protocol; the ISI module acquires state data of the high-pressure injector system in real time; The acquired state data is encapsulated, a data frame is generated according to the format specified in the CAN protocol, and the data frame is sent to the breast X-ray system through the CAN bus; after receiving the data frame, the breast X-ray system performs analysis and processing to obtain real-time state information of the injector, and displays the information on the system interface.

5. The method of claim 4, wherein: when it is necessary to configure or query the related parameters of the high-pressure injector system, the breast X-ray system sends a read-write request instruction for the object dictionary to the ISI module through the CAN bus, and the instruction specifies the object dictionary entry to be operated and the corresponding read-write operation type; after receiving the read-write request instruction, the ISI module analyzes the instruction and accesses the object dictionary according to the instruction; if it is a read operation, the data of the corresponding entry in the object dictionary is read and returned to the breast X-ray system after being encapsulated according to the CAN protocol format; if it is a write operation, the new data carried in the instruction is written into the corresponding entry of the object dictionary to complete the configuration update of the parameters.

6. The method of claim 5, wherein: operation plans of the high-pressure injector system are preset on the breast X-ray system; When the preset plan execution condition is met, the breast X-ray system sends a control instruction to the ISI module through the CAN bus, and the ISI module controls the injector to perform corresponding operations according to the instruction content, so as to ensure that the injection process meets the requirements of the examination process; The breast X-ray system sends a linkage control instruction to the ISI module through the CAN bus according to the examination process and requirements and the injector state information obtained from the ISI module; The ISI module coordinates the operation of the high-pressure injector system and the imaging action of the breast X-ray system according to the received linkage control instruction.

7. The method of claim 6, wherein: The required injection parameters are set in the high-pressure injector system, and the contrast agent is prepared in the high-pressure injector system; When the high-pressure injector system completes the injection parameter setting and the contrast agent preparation, the injection communication module detects that the system is in a ready state, and the internal circuit of the injection communication module makes the level state of a specific input / output port IO10 low, so as to feed back to the breast X-ray system that the high-pressure injector system is in a ready state and waits for further instructions from the breast X-ray system; The injection parameters set in the high-pressure injector system are verified on the operation interface of the breast X-ray system, and it is checked whether the parameters meet the requirements of the breast X-ray examination, so as to ensure that the injection process can cooperate with the imaging examination; After the verified parameters are correct, the breast X-ray system sends an injection command to the injection communication module through the internal control logic, and in the process of sending the injection command, the level states of another group of specific input / output ports IO8 and IO2 of the injection communication module are simultaneously low, so as to transmit the injection start signal to the high-pressure injector system; The high-pressure injector system continuously monitors the input / output port state of the injection communication module, and when it detects that the level of the input / output ports IO8 and IO2 is low, it identifies that it is a valid injection command from the breast X-ray system, and then starts the injection program to complete the contrast agent injection operation according to the pre-set injection parameters.

8. The method of claim 7, wherein: During the contrast agent injection process, the high-pressure injector system generates an injection command, and controls the level states of specific input / output ports IO5 and IO11 of the injection communication module to be simultaneously low through the internal circuit, so as to send the injection command to the breast X-ray system; after receiving the command, the breast X-ray system converts it into identifiable information and displays it on the operation interface, and starts an internal timer to record the time information of the injection process; When the contrast agent injection is completed, the high-pressure injector system generates an injection completion command, and makes the level states of another group of specific input / output ports IO6 and IO12 of the injection communication module to be simultaneously low, so as to transmit the injection completion command to the breast X-ray system. The breast X-ray system is operated before the exposure countdown arrives; when the exposure countdown of the breast X-ray system ends, a specific operation instruction is executed on the operation interface of the breast X-ray system, triggering the breast X-ray system to perform spectral enhancement photography; the breast X-ray system completes X-ray exposure of low energy and high energy in turn according to a preset program, and obtains breast image information under different energies.

9. The method of claim 3, wherein: The reconstructed and subtracted breast spectral image data is processed; Based on the OpenGL rendering module, the post-processed dual-energy subtraction image data is rendered in real time, and the image data is converted into a graphical image that can be intuitively presented on a display device; Then, the rendered image is output in real time on the operation interface of the breast X-ray system or a designated display device; The DICOMEditor software tool or related function library is called to analyze the preset DICOM template; After the parameter filling is completed, the rendered dual-energy subtraction image data is integrated with the DICOM template with the filled parameters, and a complete dual-energy subtraction DICOM image file is generated according to the format specification of the DICOM file.

10. The method of claim 9, wherein: The collected breast spectral image data is first subjected to noise suppression and correction processing, and a median filtering algorithm is used for noise suppression of the image, and the median filtering formula is: wherein, f s t are pixel values of the original image at coordinates s t S xy is a filter window centered at coordinates x y g x y are pixel values of the median filtered image at coordinates x y ​​​​​​​​​​ Based on the physical model of spectral imaging, the low-energy and high-energy exposed image data are reconstructed by using the maximum expectation EM algorithm; the observed low-energy and high-energy image data are respectively Y L and Y H The hidden breast tissue attenuation coefficient distribution is X The iteration formula of the EM algorithm is: wherein, A and B are the system matrices of the low and high energy imaging systems, respectively, describing the mapping from the tissue attenuation coefficients to the observed images; N and M are the number of pixels of the low and high energy images, respectively; k is the number of iterations. The reconstructed low energy image IL and the high energy image IH are subjected to a subtraction operation, denoted as: wherein, I sub to subtract the image, ks is a subtraction coefficient.

Images