Oil-in-water emulsion composition

Abstract

The present invention provides an oil-in-water emulsion composition which contains the following components (A), (B), (C) and (D): (A) a ceramide, (B) an oil agent that is liquid at 25 DEG C, (C) a nonionic surfactant having an HLB of less than 10, and (D) water, and which has a Z-average particle diameter of emulsified particles of 0.05-0.3 [mu] m.

Description

TECHNICAL FIELD

[0001] The present application relates to an oil-in-water emulsified composition and a method for producing the same. BACKGROUND

[0002] In the intercellular space of the horny cells constituting the horny layer existing on the outermost layer of the skin, there is a lipid called "intercellular lipid of horny cells". About 50% of the intercellular lipid of horny cells is ceramide, which is closely related to rough skin and dry skin, and it is known that the state of the horny layer can be improved by externally supplementing ceramide.

[0003] However, if a solid lipid such as ceramide is incorporated into a cosmetic, it is difficult to stabilize the solid lipid in the formulation because the solid lipid has high crystallinity and a high melting point, and therefore, techniques for stably incorporating them have been studied.

[0004] For example, Patent Literature 1 describes a translucent cosmetic containing ceramide, an oily ingredient, a nonionic surfactant, and water, and an O / W emulsion formed by them, the average particle diameter of which is 100 nm to 300 nm, which is excellent in temporal stability and has a beautiful appearance.

[0005] (Patent Literature 1) International Publication No. 2004 / 045566 SUMMARY

[0006] The present application relates to an oil-in-water emulsified composition, which contains the following components (A), (B), (C), and (D):

[0007] (A) a ceramide or the like,

[0008] (B) an oil agent that is liquid at 25°C,

[0009] (C) a nonionic surfactant having an HLB of less than 10, and

[0010] (D) water,

[0011] and the Z-average particle diameter of the emulsified particles is 0.05 to 0.3 μm.

[0012] Further, the present application relates to a method for producing the above-mentioned oil-in-water emulsified composition, which includes: a step 1 of obtaining an oil phase containing the component (A), the component (B), and the component (C); and a step 2 of mixing the oil phase obtained in the step 1 with an aqueous phase containing the component (D). DETAILED DESCRIPTION

[0013] Existing cosmetics do not sufficiently provide smoothness and a moisturizing feeling to the skin after application. In addition, there are problems in terms of storage stability.

[0014] The present inventors have found that an oil-in-water emulsified composition having excellent storage stability, smooth skin after application, and excellent moisturizing feeling can be obtained by using a combination of ceramides, liquid oil agents, and specific nonionic surfactants, and stably emulsifying and dispersing the ceramide-containing oil phase into fine particles.

[0015] The oil-in-water emulsified composition of the present application stably emulsifies and disperses the ceramide-containing oil phase into fine particles, and thus has excellent storage stability, smooth skin after application, and excellent moisturizing feeling.

[0016] As the component (A) ceramides used in the present application, in addition to natural ceramides 1, 2, 3, 4, 5, 6, 7, and the like, sphingosine derivatives such as phytosphingosine, and the like, there can be cited, for example, ceramide-like structural substances described in Japanese Patent Laid-Open No. 62-228048, Japanese Patent Laid-Open No. 63-216812, Japanese Patent Laid-Open No. 63-227513, Japanese Patent Laid-Open No. 64-29347, Japanese Patent Laid-Open No. 64-31752, Japanese Patent Laid-Open No. 8-319263, and the like. As the ceramide-like structural substances, specifically, from the viewpoint of making the ceramide-containing oil into fine particles and the viewpoint of improving storage stability, there can be cited, for example, compounds represented by the following general formulas (1) and (2):

[0017]

[0018] [In the formula, R 1b represents a hydrocarbon group having 10 to 26 carbon atoms, R 2b represents a hydrocarbon group having 9 to 25 carbon atoms, and X represents -(CH2) n (wherein n represents an integer of 2 to 6).]

[0019]

[0020] (In the formula, R 1 and R 2 are the same or different and represent a hydroxylatable hydrocarbon group having 1 to 40 carbon atoms; R 3 represents an alkylene group having 1 to 6 carbon atoms or a single bond; and R 4 represents a hydrogen atom, an alkoxy group having 1 to 12 carbon atoms, or a 2,3-dihydroxypropoxy group. When R 3 is a single bond, R 4 is a hydrogen atom.)

[0021] Further, in the above general formulas (1) and (2), as the hydrocarbon group, an alkyl group or an alkenyl group is preferable.

[0022] As examples of the compound of general formula (1), there can be mentioned, for example, N- (hexadecyloxyhydroxypropyl) -N-hydroxyethyl hexadecanamide, and as examples of the compound of general formula (2), there can be mentioned, for example, long-chain dibasic acid bis 3-methoxypropionamide.

[0023] The compound represented by general formula (1) is a ceramide-like compound, and belongs to a ceramide functional component, and has a ceramide- supplementing action, and can improve the skin condition (moisture content, etc.).

[0024] From the viewpoint of making the oil containing the ceramide-like compound into fine particles and the viewpoint of improving the storage stability, as the component (A), one or two or more selected from natural ceramides, sphingosines, the compounds represented by general formulae (1) and (2) above are preferable; one or two or more selected from natural ceramides, sphingosines, the compound represented by general formula (1) above are more preferable; one or two or more selected from natural ceramides, phytosphingosine, N- (hexadecyloxyhydroxypropyl) -N-hydroxyethyl hexadecanamide are particularly preferable; and N- (hexadecyloxyhydroxypropyl) -N-hydroxyethyl hexadecanamide is further more preferable.

[0025] The component (A) can be used one or two or more, and from the viewpoint of making the oil containing the ceramide-like compound into fine particles, the viewpoint of improving the storage stability, and the viewpoint of improving the moisturizing feeling of the skin after application, the content thereof in the total composition is preferably 0.3% by mass or more, more preferably 0.5% by mass or more, particularly preferably 0.6% by mass or more, further more preferably 0.7% by mass or more, further particularly preferably 0.8% by mass or more, and in addition, preferably 4% by mass or less, more preferably 3% by mass or less, particularly preferably 2% by mass or less, further more preferably 1.8% by mass or less, further particularly preferably 1.3% by mass or less.

[0026] In addition, the content of the component (A) in the total composition is preferably 0.3 to 4% by mass, more preferably 0.5 to 3% by mass, particularly preferably 0.6 to 2% by mass, further more preferably 0.7 to 1.8% by mass, further particularly preferably 0.8 to 1.3% by mass.

[0027] In addition, the content of the component (A) in the total composition is preferably 0.3 to 2% by mass, more preferably 0.3 to 1.8% by mass, particularly preferably 0.5 to 1.5% by mass.

[0028] The component (B) is an oil agent that is in a liquid state at 25°C. The "liquid state" means fluidity, and also includes a paste state.

[0029] As the oil agent of the component (B), there can be mentioned, for example, hydrocarbon oils, ester oils, ether oils, higher alcohols, silicone oils, higher fatty acids, etc.

[0030] More specifically, as the hydrocarbon oil, for example, squalane, liquid paraffin, liquid isoparaffin, light liquid isoparaffin, heavy liquid isoparaffin, etc. can be exemplified.

[0031] As the hydrocarbon oil, from the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application, it is preferable to contain one or two or more kinds selected from squalane, liquid paraffin, liquid isoparaffin, light liquid isoparaffin, more preferable to contain one or two or more kinds selected from squalane, liquid paraffin, liquid isoparaffin, particularly preferable to contain one or more kinds selected from squalane, liquid isoparaffin, and further more preferable to contain liquid isoparaffin. In addition, liquid isoparaffin is also called "hydrogenated polyisobutene".

[0032] As the ester oil, for example, monoester oil, diester oil, triester oil, and tetraester oil can be exemplified.

[0033] As the monoester oil, for example, monoester of aliphatic or aromatic monocarboxylic acid or dicarboxylic acid having 2 to 24 carbon atoms can be exemplified, and as specific examples, for example, cetyl 2-ethylhexanoate, cetyl octanoate, isononyl isononanoate, isotridecyl isononanoate, isostearyl isostearate, hexyl laurate, isopropyl myristate, octyldodecyl myristate, myristyl myristate, 2-hexyldecyl myristate, isopropyl palmitate, octyl palmitate, 2-hexyldecyl palmitate, butyl stearate, isocetyl stearate, isocetyl isostearate, decyl oleate, isodecyl benzoate, octyl methoxycinnamate, dimethyl octanoyl hexyldecyl lactate, cetyl lactate, myristyl lactate, lanolin acetate, 2-ethylhexyl succinate, 2-hexyldecyl adipate, alkyl (C12 to C15) benzoate, jojoba oil, etc. can be exemplified.

[0034] As the monoester oil, from the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application, it is preferable to contain one or two or more kinds selected from isononyl isononanoate, isotridecyl isononanoate, isostearyl isostearate, octyldodecyl myristate, jojoba oil, more preferable to contain one or two or more kinds selected from isononyl isononanoate, isotridecyl isononanoate, isostearyl isostearate, jojoba oil, and particularly preferable to contain isononyl isononanoate.

[0035] As the diester oil, for example, a diester of a dicarboxylic acid having 3 to 18 carbon atoms, a di-fatty acid ester of a polyhydric alcohol, etc. can be exemplified. As specific examples, for example, propylene glycol dioctanoate, neopentyl glycol dicaprate, ethylene glycol distearate, propylene glycol diisostearate, glycerin monomyristate monomyristate, glycerin di-2- heptylundecanoate, di-2-ethylhexyl succinate, diisopropyl sebacate, diisostearyl malate, ethylene glycol di-2-ethylhexanoate, diisobutyl adipate, di-2-heptylundecyl adipate, di-2- ethylhexyl sebacate, etc. can be exemplified.

[0036] From the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application, as the diester oil, it is preferable to contain one or more selected from propylene glycol dioctanoate, neopentyl glycol dicaprate, and more preferable to contain neopentyl glycol dicaprate.

[0037] As the triester oil, for example, a tri-fatty acid ester of a polyhydric alcohol of three or more, specifically, for example, glycerin trimyristate, glycerin triisopalmitate, glycerin tri-2- heptylundecanoate, trimethylolpropane triethylhexanoate, trimethylolpropane trioctanoate, glycerin tri(caprylate / caprate), glycerin trioleate, glycerin tri-2-ethylhexanoate, glycerin triisostearate, and olive oil, kukui nut oil, meadowfoam oil, castor oil, safflower oil, sunflower seed oil, avocado oil, rapeseed oil, almond oil, rice germ oil, rice bran oil, and other plant oils, etc. can be exemplified.

[0038] From the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application, as the triester oil, it is preferable to contain one or two or more selected from glycerin tri(caprylate / caprate), glycerin tri-2-ethylhexanoate, and plant oils, and more preferable to contain one or more selected from glycerin tri(caprylate / caprate) and olive oil, and particularly preferable to contain glycerin tri(caprylate / caprate).

[0039] As the tetraester oil, for example, a tetra-fatty acid ester of a polyhydric alcohol of four or more, specifically, for example, pentaerythritol tetra(behenate / benzoate / ethylhexanoate), pentaerythritol tetraethylhexanoate, pentaerythritol tetraoctanoate, pentaerythritol tetra-2-ethylhexanoate can be exemplified.

[0040] From the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application, as the ester oil, it is preferable to contain one or two or more selected from the monoester oil, the diester oil, and the triester oil, and more preferable to contain one or more selected from the monoester oil and the diester oil, and particularly preferable to contain the diester oil.

[0041] In addition, as the ester oil, an ester oil having a hydroxyl group in the structure can be used, and an ester oil not having a hydroxyl group can also be used, and from the viewpoint of making the oil containing the ceramide into fine particles and the viewpoint of improving the storage stability, an ester oil not having a hydroxyl group in the structure is preferred.

[0042] As the ether oil, for example, a dialkyl ether can be exemplified, and specifically, for example, dihexyl ether, dioctyl ether, cetyl-1,3-dimethylbutyl ether, and the like can be exemplified, and cetyl-1,3-dimethylbutyl ether is preferred.

[0043] As the higher alcohol, for example, a higher alcohol having a linear or branched alkyl group or alkenyl group having 10 to 24 carbon atoms can be exemplified, and for example, lauryl alcohol, myristyl alcohol, isocetyl alcohol, isostearyl alcohol, 2-octyldodecanol, oleyl alcohol, and the like can be exemplified.

[0044] As the silicone oil, for example, a linear dimethylpolysiloxane such as volatile, non-volatile dimethylpolysiloxane (1 cs), dimethylpolysiloxane (1.5 cs), dimethylpolysiloxane (2 cs), dimethylpolysiloxane (6 cs), a branched siloxane such as methyltrimethicone, tristrimethylsilylmethylsilane, tetratrimethylsilylsilane, a cyclic dimethylsiloxane such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, a methylphenylpolysiloxane such as diphenylsiloxylphenyltrimethylsiloxane, and the like can be exemplified.

[0045] From the viewpoint of making the oil containing the ceramide into fine particles, the viewpoint of improving the storage stability, the viewpoint of improving the smoothness of the skin after application, and the viewpoint of improving the moisturizing feeling of the skin after application, as the silicone oil, one or two or more kinds selected from a linear dimethylpolysiloxane and a branched siloxane are preferred, a linear dimethylpolysiloxane is more preferred, and one or more kinds selected from dimethylpolysiloxane (2 cs) and dimethylpolysiloxane (6 cs) are particularly preferred, and further, dimethylpolysiloxane (2 cs) is much more preferred.

[0046] As the higher fatty acid, for example, oleic acid, isostearic acid, undecylenic acid, and the like can be exemplified.

[0047] As the oil agent of component (B), from the viewpoint of making the oil containing the ceramide into fine particles, the viewpoint of improving the storage stability, and the viewpoint of improving the moisturizing feeling of the skin after application, (B1) a hydrocarbon oil, (B2) a polar oil, and a silicone oil are preferred, and (B1) a hydrocarbon oil and (B2) a polar oil are more preferred.

[0048] From the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moisturizing feeling of the skin after application, as the (B2) polar oil, it is preferable to contain one or two or more selected from ester oils, ether oils, higher fatty acids, and more preferable to contain ester oils.

[0049] From the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moisturizing feeling of the skin after application, the content of component (B1) in the total composition is preferably 0.1% by mass or more, more preferably 0.3% by mass or more, particularly preferably 0.5% by mass or more, and further more preferably 1.5% by mass or more, and on the other hand, is preferably 5% by mass or less, more preferably 4% by mass or less, particularly preferably 3% by mass or less, and further more preferably 2.5% by mass or less. In addition, the content of component (B1) in the total composition is preferably 0.1 to 5% by mass, more preferably 0.3 to 4% by mass, particularly preferably 0.5 to 3% by mass, and further more preferably 1.5 to 2.5% by mass. In addition, the content of component (B1) in the total composition is preferably 0.5 to 2.5% by mass.

[0050] The content of component (B2) in the total composition is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, particularly preferably 0.3% by mass or more, further more preferably 0.5% by mass or more, and further particularly preferably 1.5% by mass or more, and on the other hand, is preferably 3.5% by mass or less, more preferably 2.8% by mass or less, particularly preferably 2.5% by mass or less, further more preferably 2.3% by mass or less, and further particularly preferably 2.1% by mass or less. In addition, the content of component (B2) in the total composition is preferably 0.05 to 3.5% by mass, more preferably 0.1 to 2.8% by mass, particularly preferably 0.3 to 2.5% by mass, further more preferably 0.5 to 2.3% by mass, and further particularly preferably 1.5 to 2.1% by mass. In addition, the content of component (B2) in the total composition is preferably 0.3 to 3.5% by mass, more preferably 1.5 to 2.5% by mass.

[0051] In the present application, as component (B), in the case of containing components (B1) and (B2), from the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moisturizing feeling of the skin after application, the mass ratio (B1) / (B2) of component (B1) to component (B2) is preferably 0.05 or more, more preferably 0.1 or more, particularly preferably 0.5 or more, and further more preferably 0.7 or more, and on the other hand, is preferably 6 or less, more preferably 3 or less, particularly preferably 2.5 or less, and further more preferably 2 or less.

[0052] In addition, the mass ratio (B1) / (B2) of component (B1) to component (B2) is preferably from 0.05 to 6, more preferably from 0.1 to 3, particularly preferably from 0.5 to 2.5, and further more preferably from 0.7 to 2. In addition, the mass ratio (B1) / (B2) of component (B1) to component (B2) is preferably from 0.5 to 6, more preferably from 0.7 to 3, and particularly preferably from 0.7 to 2.5.

[0053] Component (B) can be used singly or in combination of two or more kinds, and the content thereof in the total composition is preferably 0.15% by mass or more, more preferably 1% by mass or more, particularly preferably 3% by mass or more, and further more preferably 5% by mass or more, from the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application, and is preferably 9% by mass or less, more preferably 7.5% by mass or less, particularly preferably 7% by mass or less, and further more preferably 6.5% by mass or less.

[0054] In addition, the content of component (B) in the total composition is preferably from 0.15 to 9% by mass, more preferably from 1 to 7.5% by mass, particularly preferably from 3 to 7% by mass, and further more preferably from 5 to 6.5% by mass. In addition, the content of component (B) in the total composition is preferably from 1 to 9% by mass.

[0055] In the present application, the mass ratio (A) / (B) of component (A) to component (B) is preferably 0.05 or more, more preferably 0.1 or more, particularly preferably 0.12 or more, and further more preferably 0.15 or more, and is preferably 1 or less, more preferably 0.4 or less, particularly preferably 0.3 or less, and further more preferably 0.2 or less, from the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application.

[0056] In addition, the mass ratio (A) / (B) of component (A) to component (B) is preferably from 0.05 to 1, more preferably from 0.1 to 0.4, particularly preferably from 0.12 to 0.3, and further more preferably from 0.15 to 0.2. In addition, the mass ratio (A) / (B) of component (A) to component (B) is preferably from 0.05 to 0.4, and more preferably from 0.05 to 0.3.

[0057] Component (C) is a nonionic surfactant having an HLB of less than 10.

[0058] Here, HLB [Hydrophilic-Lipophilic Balance] is a value indicating the proportion of the molecular weight of the hydrophilic group in the total molecular weight of the surfactant. In the present application, the HLB value is calculated according to the Griffin formula for nonionic surfactants.

[0059] As the nonionic surfactant having an HLB of less than 10, if it is a component used in general cosmetics, there is no limitation, and examples thereof include polyoxyethylene fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene alkyl ethers, polyoxyethylene sorbitol fatty acid esters, polyoxyethylene glycerin fatty acid esters, polyoxyethylene propylene glycol fatty acid esters, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyethylene hydrogenated castor oil fatty acid esters, polyoxyethylene phytostanol ethers, polyoxyethylene phytosterol ethers, polyoxyethylene cholestanol ethers, polyoxyethylene cholesterol ethers, silicone surfactants such as polyether-modified silicones, and the like.

[0060] As the nonionic surfactant having an HLB of less than 10, from the viewpoint of making the oil containing the ceramide fine particles and the viewpoint of improving the storage stability, the HLB is preferably 7 or less, more preferably 5 or less. In addition, the HLB is preferably 1 or more, more preferably 3 or more.

[0061] Among these, from the viewpoint of making the oil containing the ceramide fine particles and the viewpoint of improving the storage stability, it is preferable to contain one or two or more selected from the group consisting of polyether-modified silicones, glycerin fatty acid esters, alkyl glyceryl ethers, and sorbitan fatty acid esters, more preferably one or more selected from the group consisting of glycerin fatty acid esters and sorbitan fatty acid esters, and particularly preferably sorbitan fatty acid esters.

[0062] The content of the component (C) is preferably 0.1% by mass or more, more preferably 0.4% by mass or more, particularly preferably 0.5% by mass or more, and further more preferably 0.55% by mass or more, and is preferably 3% by mass or less, more preferably 2.5% by mass or less, particularly preferably 1.8% by mass or less, and further more preferably 1.4% by mass or less, in the total composition, from the viewpoint of making the oil containing the ceramide fine particles and the viewpoint of improving the storage stability.

[0063] In addition, the content of the component (C) is preferably 0.1 to 3% by mass, more preferably 0.4 to 2.5% by mass, particularly preferably 0.5 to 1.8% by mass, and further more preferably 0.55 to 1.4% by mass, in the total composition. In addition, the content of the component (C) is preferably 0.1 to 2.5% by mass, in the total composition.

[0064] In the present application, the mass ratio (A) / (C) of component (A) to component (C) is preferably 0.05 or more, more preferably 0.1 or more, particularly preferably 0.5 or more, further more preferably 0.6 or more, further particularly preferably 0.8 or more, and on the other hand, preferably 10 or less, more preferably 5 or less, particularly preferably 2.5 or less, further more preferably 2.2 or less, further particularly preferably 1.8 or less, from the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application.

[0065] In addition, the mass ratio (A) / (C) of component (A) to component (C) is preferably 0.05 to 10, more preferably 0.1 to 5, particularly preferably 0.5 to 2.5, further more preferably 0.6 to 2.2, further particularly preferably 0.8 to 1.8. In addition, the mass ratio (A) / (C) of component (A) to component (C) is preferably 0.1 to 10.

[0066] In the present application, the mass ratio (B) / (C) of component (B) to component (C) is preferably 0.05 or more, more preferably 1 or more, particularly preferably 3 or more, further more preferably 3.5 or more, further particularly preferably 4.5 or more, and on the other hand, preferably 40 or less, more preferably 20 or less, particularly preferably 15 or less, further more preferably 12 or less, further particularly preferably 10 or less, from the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application.

[0067] In addition, the mass ratio (B) / (C) of component (B) to component (C) is preferably 0.05 to 40, more preferably 1 to 20, particularly preferably 3 to 15, further more preferably 3.5 to 12, further particularly preferably 4.5 to 10. In addition, the mass ratio (B) / (C) of component (B) to component (C) is preferably 1 to 40.

[0068] In the present application, the content of water in component (D) is preferably 50 mass% or more, more preferably 60 mass% or more, particularly preferably 70 mass% or more, and on the other hand, preferably 95 mass% or less, more preferably 90 mass% or less, particularly preferably 88 mass% or less, in the total composition, from the viewpoint of making the oil containing ceramides into fine particles, the viewpoint of improving storage stability, the viewpoint of improving smoothness of the skin after application, and the viewpoint of improving the moist feeling of the skin after application.

[0069] The oil-in-water emulsion composition of the present application can further contain (E) a nonionic surfactant having an HLB of 10 or more to make the oil containing the ceramide fine particles, and to further improve the storage stability.

[0070] The nonionic surfactant of component (E) is preferably one having an HLB of 11 to 16, and more preferably one having an HLB of 12 to 15, from the viewpoint of making the oil containing the ceramide fine particles, and from the viewpoint of improving the storage stability.

[0071] The nonionic surfactant of component (E) can be exemplified by, for example, polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene alkylol ether, polyglycerin fatty acid ester, sucrose fatty acid ester, and the like. Of these, from the viewpoint of making the oil containing the ceramide fine particles, and from the viewpoint of improving the storage stability, it is preferable to contain one or more selected from polyoxyethylene hydrogenated castor oil and polyoxyethylene sorbitan fatty acid ester, and more preferable to contain polyoxyethylene sorbitan fatty acid ester.

[0072] In addition, in the polyoxyethylene hydrogenated castor oil, the average addition mole number of the polyoxyethylene chain constituting the polyoxyethylene hydrogenated castor oil is preferably 25 to 100, more preferably 35 to 85, particularly preferably 45 to 75, further more preferably 55 to 65, and further particularly preferably 60, from the viewpoint of making the oil containing the ceramide fine particles, and from the viewpoint of improving the storage stability.

[0073] In the polyoxyethylene sorbitan fatty acid ester, the average addition mole number of the polyoxyethylene chain constituting the polyoxyethylene sorbitan fatty acid ester is preferably 10 to 30, more preferably 15 to 25, and particularly preferably 20, from the viewpoint of making the oil containing the ceramide fine particles, and from the viewpoint of improving the storage stability. In the polyoxyethylene sorbitan fatty acid ester, the number of carbon atoms of the alkyl group constituting the polyoxyethylene sorbitan fatty acid ester is preferably 10 to 25, more preferably 16 to 20, and particularly preferably 18, from the viewpoint of making the oil containing the ceramide fine particles, and from the viewpoint of improving the storage stability.

[0074] The nonionic surfactant of component (E) can be used alone or in combination of two or more, and the content thereof in the total composition is preferably 0.5% by mass or more, more preferably 1% by mass or more, and particularly preferably 1.4% by mass or more, from the viewpoint of making the oil containing the ceramide fine particles, and from the viewpoint of improving the storage stability, and is preferably 3% by mass or less, more preferably 2.5% by mass or less, and particularly preferably 2% by mass or less. In addition, the content of component (E) in the total composition is preferably 0.5 to 3% by mass, more preferably 1 to 2.5% by mass, and particularly preferably 1.4 to 2% by mass.

[0075] The oil-in-water emulsion composition of the present application can further contain an ionic surfactant to make the oil containing ceramide into fine particles, and to improve the storage stability.

[0076] As the ionic surfactant, for example, anionic surfactants, cationic surfactants, amphoteric surfactants can be exemplified.

[0077] As the anionic surfactant, for example, sodium laurate, potassium palmitate, stearic acid arginine, and the like, fatty acids or salts thereof having 12 to 22 carbon atoms can be exemplified.

[0078] Sodium lauryl sulfate, potassium lauryl sulfate, sodium cetyl sulfate, and the like, alkyl sulfates or salts thereof having 12 to 22 carbon atoms can be exemplified.

[0079] Triethanolamine polyoxyethylene lauryl sulfate, and the like, alkyl ether sulfates or salts thereof having 12 to 22 carbon atoms can be exemplified.

[0080] Sodium lauroyl sarcosinate, and the like, N-acyl sarcosinates or salts thereof having 12 to 22 carbon atoms can be exemplified.

[0081] Sodium monostearyl phosphate, and the like, alkyl phosphates or salts thereof having 12 to 22 carbon atoms can be exemplified.

[0082] Sodium polyoxyethylene oleyl ether phosphate, sodium polyoxyethylene stearyl ether phosphate, and the like, polyoxyethylene alkyl ether phosphates or salts thereof having 12 to 22 carbon atoms can be exemplified.

[0083] Sodium di-2-ethylhexyl sulfosuccinate, and the like, dialkyl sulfosuccinates or salts thereof having 12 to 24 carbon atoms can be exemplified.

[0084] Sodium N-stearoyl-N-methyl taurate, and the like, N-alkanoyl methyl taurates or salts thereof having 12 to 22 carbon atoms can be exemplified.

[0085] Sodium dilauroyl glutamate, monosodium N-lauroyl glutamate, sodium N-stearoyl-L-glutamate, N-stearoyl-L-glutamic acid arginine, sodium N-stearoyl glutamate, sodium N-myristoyl-L-glutamate, and the like, N-acyl glutamic acids or salts thereof having 12 to 22 carbon atoms can be exemplified.

[0086] As the N-alkanoyl methyl taurate or salt thereof having 12 to 22 carbon atoms, from the viewpoint of making the oil containing ceramide into fine particles and the viewpoint of improving the storage stability, sodium N-stearoyl-N-methyl taurate is preferable.

[0087] As the N-acyl glutamic acid or salt thereof having 12 to 22 carbon atoms, from the viewpoint of making the oil containing ceramide into fine particles and the viewpoint of improving the storage stability, sodium N-stearoyl-L-glutamate is preferable.

[0088] In addition, sodium N-stearoyl-N-methyl taurate is also referred to as "stearoyl methyl taurine Na", and sodium N-stearoyl-L-glutamate is also referred to as "stearoyl glutamate Na".

[0089] In addition, as the cationic surfactant, a quaternary ammonium salt is preferable, and examples thereof include: alkyltrimethylammonium chlorides such as stearyltrimethylammonium chloride and behenyltrimethylammonium chloride; dialkyldimethylammonium chlorides, trialkylmethylammonium chlorides, and alkylamine salts.

[0090] In addition, as the amphoteric surfactant, examples thereof include: alkyl dimethyl amine oxides, alkyl carboxybetaines, alkyl sulfobetaines, amido amino acid salts, and alkyl amido propyl betaines, and an alkyl amido propyl betaine is preferable.

[0091] As the ionic surfactant, from the viewpoint of making the oil containing a ceramide into fine particles and the viewpoint of improving the storage stability, an anionic surfactant is preferable.

[0092] In addition, as the anionic surfactant, from the viewpoint of making the oil containing a ceramide into fine particles and the viewpoint of improving the storage stability, one or more selected from the group consisting of N-alkanoyl methyl taurines having 12 to 22 carbon atoms or salts thereof, and N-acyl glutamic acids having 12 to 22 carbon atoms or salts thereof are preferable, N-alkanoyl methyl taurines having 12 to 22 carbon atoms or salts thereof are more preferable, and N-stearoyl-N-methyl taurine or a salt thereof is particularly preferable.

[0093] The ionic surfactant can be used alone or in combination with two or more, and from the viewpoint of making the oil containing a ceramide into fine particles and the viewpoint of improving the storage stability, the content thereof in the total composition is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, particularly preferably 0.13% by mass or more, further more preferably 0.15% by mass or more, further particularly preferably 0.18% by mass or more, and on the other hand, is preferably 2% by mass or less, more preferably 1% by mass or less, particularly preferably 0.8% by mass or less, further more preferably 0.5% by mass or less, further particularly preferably 0.45% by mass or less. In addition, the content of the ionic surfactant in the total composition is preferably 0.05 to 2% by mass, more preferably 0.1 to 1% by mass, particularly preferably 0.13 to 0.8% by mass, further more preferably 0.15 to 0.5% by mass, further particularly preferably 0.18 to 0.45% by mass. In addition, the content of the ionic surfactant is preferably 0.1 to 2% by mass, more preferably 0.1 to 0.8% by mass.

[0094] The oil-in-water emulsion composition of the present application can further contain a polyol, which can make the oil containing the ceramide fine particles, and can improve the storage stability. The polyol is a compound having two or more hydroxyl groups in the molecule, and can be any ingredient used in general cosmetics.

[0095] As the dihydric alcohol, for example, ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, polypropylene glycol, 1,3-butanediol, 1,3-propanediol, pentanediol, and the like can be given. As the trihydric alcohol, for example, glycerin, trimethylolpropane, and the like can be given. As the tetrahydric alcohol, for example, diglycerin, erythritol, and the like can be given. As the polyhydric alcohol of five or more, for example, polyglycerin such as triglycerin; saccharides such as glucose, maltose, maltulose, sucrose, xylitol, sorbitol, maltitol, polyoxyethylene methyl glucoside, polyoxyethylene ethyl glucoside, polyoxyethylene propylene glucoside, and sugar alcohols can be given.

[0096] Of these, from the viewpoint of making the oil containing the ceramide fine particles, and the viewpoint of improving the storage stability, it is preferable to contain one or more selected from dihydric alcohol and trihydric alcohol, more preferable to contain dihydric alcohol, and particularly preferable to contain one or more selected from 1,3-butanediol and dipropylene glycol.

[0097] The polyhydric alcohol can be used singly or in combination of two or more, and from the viewpoint of making the oil containing the ceramide fine particles, and the viewpoint of improving the storage stability, the content is preferably 1% by mass or more, more preferably 1.3% by mass or more, particularly preferably 1.5% by mass or more, and further more preferably 1.8% by mass or more in the total composition, and on the other hand, is preferably 30% by mass or less, more preferably 20% by mass or less, particularly preferably 15% by mass or less, and further more preferably 12% by mass or less. In addition, the content of the polyhydric alcohol is preferably 1 to 30% by mass, more preferably 1.3 to 20% by mass, particularly preferably 1.5 to 15% by mass, and further more preferably 1.8 to 12% by mass in the total composition.

[0098] In addition, as the polyhydric alcohol, when dihydric alcohol is contained, the dihydric alcohol can be used singly or in combination of two or more, and from the viewpoint of making the oil containing the ceramide fine particles, and the viewpoint of improving the storage stability, the content is preferably 1% by mass or more, more preferably 1.3% by mass or more, particularly preferably 1.5% by mass or more, and further more preferably 1.8% by mass or more in the total composition, and on the other hand, is preferably 30% by mass or less, more preferably 20% by mass or less, particularly preferably 15% by mass or less, and further more preferably 10% by mass or less. In addition, the content of the dihydric alcohol is preferably 1 to 30% by mass, more preferably 1.3 to 20% by mass, particularly preferably 1.5 to 15% by mass, and further more preferably 1.8 to 10% by mass in the total composition.

[0099] The oil-in-water emulsified composition of the present application can contain, in addition to the above-mentioned components, components generally used in cosmetics, such as an oil component other than component (B), a water-soluble polymer, an antioxidant, a perfume, a preservative, a pH adjustor, a blood circulation promoter, a cooling agent, an antiperspirant, a bactericide, a skin activator, a humectant other than a polyhydric alcohol, a cooling agent, a coloring agent, and the like.

[0100] The method for producing the oil-in-water emulsified composition of the present application includes: a step 1 of obtaining an oil phase containing component (A), component (B), and component (C); and a step 2 of mixing the oil phase obtained in step 1 with an aqueous phase containing component (D).

[0101] The oil-in-water emulsified composition of the present application preferably contains a glycol from the viewpoint of obtaining a fine emulsified product, and as a method for producing the same, a method for producing an oil-in-water emulsified composition including: a step 1 of obtaining an oil phase containing component (A), component (B), component (C), a glycol, and a part of component (D); and a step 2 of mixing the oil phase obtained in step 1 with an aqueous phase containing the remaining part of component (D) is preferred.

[0102] In step 1, the oil phase contains a part of the water of component (D) and the glycol, and from the viewpoint of obtaining a fine emulsified product, the oil phase obtained in step 1 is preferably transparent to the eye (at the temperature at the time of mixing). In this case, the content of the glycol in the oil phase of step 1 is preferably 5% by mass or more, more preferably 8% by mass or more, from the viewpoint of obtaining a fine emulsified product, and is preferably 30% by mass or less, more preferably 25% by mass or less, from the same viewpoint. In addition, the content of the water of component (D) in the oil phase of step 1 is preferably 2% by mass or more, more preferably 5% by mass or more, from the viewpoint of obtaining a fine emulsified product, and is preferably 10% by mass or less, more preferably 8% by mass or less, from the same viewpoint.

[0103] The content of the component (A) in the oil phase of Step 1 is preferably 1% by mass or more, more preferably 2% by mass or more, from the viewpoint of improving the moisturizing feeling of the skin after application, and is preferably 15% by mass or less, more preferably 13% by mass or less, from the viewpoint of obtaining a fine emulsion. The content of the component (B) in the oil phase of Step 1 is preferably 20% by mass or more, more preferably 30% by mass or more, from the viewpoint of improving the moisturizing feeling of the skin after application, and is preferably 90% by mass or less, more preferably 80% by mass or less, from the viewpoint of obtaining a fine emulsion. The content of the component (C) in the oil phase of Step 1 is preferably 2% by mass or more, more preferably 3% by mass or more, from the viewpoint of obtaining a fine emulsion, and is preferably 30% by mass or less, more preferably 20% by mass or less, from the viewpoint of obtaining a fine emulsion.

[0104] The oil phase of Step 1 can contain the component (E) or other surfactants and the like as other components. In addition, the water phase can contain polyhydric alcohols other than glycols and the like as other components.

[0105] In Step 2, the oil phase and the water phase obtained in Step 1 are preferably mixed while being heated to preferably 60°C or higher, more preferably 70°C or higher, and preferably 100°C or lower, from the viewpoint of obtaining a fine emulsion. In addition, it is preferable to add the oil phase of Step 1 to the water phase and mix them, from the viewpoint of obtaining a fine emulsion.

[0106] The mixing mass ratio (oil phase / water phase) of the oil phase and the water phase in Step 2 is preferably 2 / 98 or more, more preferably 5 / 95 or more, from the viewpoint of productivity, and is preferably 40 / 60 or less, more preferably 30 / 70 or less, from the viewpoint of obtaining a fine emulsion.

[0107] After the oil phase and the water phase are mixed, it is preferable to stir them for preferably 10 minutes or more and 2 hours or less, and then cool them to room temperature. The mixing can be performed using a general stirring device provided with a stirring blade.

[0108] In addition, the oil-in-water emulsion composition of the present application has a Z-average particle diameter of the emulsified particles of 0.05 to 0.3 μm, preferably 0.05 to 0.25 μm, particularly preferably 0.05 to 0.2 μm, and further more preferably 0.05 to 0.15 μm, from the viewpoint of making the oil containing a ceramide into fine particles and the viewpoint of improving the storage stability.

[0109] In the present application, the Z-average particle diameter of the emulsified particles is measured at 25°C using a Zetasizer Nano Z manufactured by Malvern Co. after diluting each oil-in-water emulsion composition 20 times. A cell is used which is a product manufactured by SARSTEDT Co. having a size of 10 x 10 x 45 mm.

[0110] In addition, by reducing the particle size, the oil-in-water emulsion composition of the present application can be made to have low viscosity. As a result, when the oil-in-water emulsion composition of the present application is used as a makeup remover as described later, the oil-in-water emulsion composition is easily absorbed into a cosmetic cotton when the oil-in-water emulsion composition is applied to the cosmetic cotton, and the cosmetic cotton does not slip on the skin surface when the skin is wiped, so that makeup dirt can be removed.

[0111] The oil-in-water emulsion composition of the present application is suitable as an oil-in-water emulsion cosmetic. It can be used, for example, as a skin care cosmetic such as a lotion, an emulsion, an essence, and the like, and a skin cosmetic such as a makeup remover. The oil-in-water emulsion composition of the present application is suitable as a makeup remover because the oil containing a ceramide is formed into fine particles and is easily permeated when applied to a cosmetic cotton.

[0112] In addition, the oil-in-water emulsion composition of the present application can be used by being absorbed into a cosmetic cotton or a sheet and wiping the skin, in addition to being applied to the hand, and being applied to the skin using the fingers.

[0113] The oil-in-water emulsion composition of the present application, when used as a makeup remover, has a viscosity at 25°C of preferably 10 to 3000 mPa-s, more preferably 10 to 1000 mPa-s, and particularly preferably 10 to 400 mPa-s, from the viewpoint of easily permeating the oil-in-water emulsion composition into a cosmetic cotton.

[0114] In addition, the viscosity of the oil-in-water emulsion composition of the present application is measured using a B-type viscometer under the following measurement conditions. In any case, the measurement temperature is 25°C.

[0115] In the case where the viscosity is 1 mPa-s or more and less than 200 mPa-s: rotor No. 1, 30 rpm, 30 seconds,

[0116] In the case where the viscosity is 200 mPa-s or more and less than 500 mPa-s: rotor No. 1, 12 rpm, 30 seconds,

[0117] In the case where the viscosity is 500 mPa-s or more and less than 2500 mPa-s: rotor No. 2, 12 rpm, 30 seconds,

[0118] In the case where the viscosity is 2500 mPa-s or more and less than 10000 mPa-s: rotor No. 3, 12 rpm, 30 seconds.

[0119] With respect to the above-described embodiments, the present application further discloses the following composition, manufacturing method, and the like.

[0120] An oil-in-water emulsified composition comprising the following components (A), (B), (C) and (D):

[0121] (A) a ceramide,

[0122] (B) an oil agent in a liquid state at 25°C,

[0123] (C) a nonionic surfactant having an HLB of less than 10, and

[0124] (D) water,

[0125] and the Z-average particle diameter of the emulsified particles is 0.05 to 0.3 μm.

[0126] <2> The oil-in-water emulsified composition described in the above <1>, wherein the ceramide of the component (A) preferably contains one or two or more selected from natural ceramides, sphingosines, and the compounds represented by the above general formulae (1) and (2):

[0127]

[0128] [In the formula, R 1b represents a hydrocarbon group having 10 to 26 carbon atoms, R 2b represents a hydrocarbon group having 9 to 25 carbon atoms, and X represents -(CH2) n (wherein n represents an integer of 2 to 6)];

[0129]

[0130] (In the formula, R 1 and R 2 are the same or different and represent a hydroxylatable hydrocarbon group having 1 to 40 carbon atoms; R 3 represents an alkylene group having 1 to 6 carbon atoms or a single bond; and R 4 represents a hydrogen atom, an alkoxy group having 1 to 12 carbon atoms, or a 2,3-dihydroxypropoxy group. When R 3 is a single bond, R 4 is a hydrogen atom);

[0131] More preferably, it contains one or two or more selected from natural ceramides, sphingosines, and the compound represented by the above general formula (1);

[0132] Particularly preferably, it contains one or two or more selected from natural ceramides, phytosphingosine, and N-(hexadecyloxyhydroxypropyl)-N-hydroxyethyldocosanoyl amide;

[0133] Further more preferably, it contains N-(hexadecyloxyhydroxypropyl)-N-hydroxyethyldocosanoyl amide.

[0134] The content of the component (A) in the total composition is preferably 0.5% by mass or more, more preferably 0.6% by mass or more, particularly preferably 0.7% by mass or more, and further more preferably 0.8% by mass or more, and is preferably 3% by mass or less, more preferably 2% by mass or less, particularly preferably 1.8% by mass or less, and further more preferably 1.3% by mass or less.

[0135] The component (B) oil agent is preferably one or two or more selected from the group consisting of hydrocarbon oils, ester oils, ether oils, higher alcohols, and silicone oils.

[0136] More preferably, the component (B) contains (B1) a hydrocarbon oil, (B2) a polar oil, and a silicone oil. Particularly preferably, the component (B) contains (B1) a hydrocarbon oil and (B2) a polar oil.

[0137] The content of the component (B1) in the total composition is preferably 0.1% by mass or more, more preferably 0.3% by mass or more, particularly preferably 0.5% by mass or more, and further more preferably 1.5% by mass or more, and is preferably 5% by mass or less, more preferably 4% by mass or less, particularly preferably 3% by mass or less, and further more preferably 2.5% by mass or less.

[0138] The content of the component (B2) in the total composition is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, particularly preferably 0.3% by mass or more, further more preferably 0.5% by mass or more, and particularly further more preferably 1.5% by mass or more, and is preferably 3.5% by mass or less, more preferably 2.8% by mass or less, particularly preferably 2.5% by mass or less, further more preferably 2.3% by mass or less, and particularly further more preferably 2.1% by mass or less.

[0139] The component (B) preferably contains the components (B1) and (B2), and the mass ratio (B1) / (B2) of the component (B1) to the component (B2) is preferably 0.05 or more, more preferably 0.1 or more, particularly preferably 0.5 or more, and further more preferably 0.7 or more, and is preferably 6 or less, more preferably 3 or less, particularly preferably 2.5 or less, and further more preferably 2 or less.

[0140] The oil-in-water emulsion composition according to any one of the above <1> to <7>, wherein the content of the component (B) is preferably 0.15% by mass or more, more preferably 1% by mass or more, particularly preferably 3% by mass or more, and further more preferably 5% by mass or more, and is preferably 9% by mass or less, more preferably 7.5% by mass or less, particularly preferably 7% by mass or less, and further more preferably 6.5% by mass or less, in the total composition.

[0141] The oil-in-water emulsion composition according to any one of the above <1> to <8>, wherein the mass ratio (A) / (B) of the component (A) to the component (B) is preferably 0.05 or more, more preferably 0.1 or more, particularly preferably 0.12 or more, and further more preferably 0.15 or more, and is preferably 1 or less, more preferably 0.4 or less, particularly preferably 0.3 or less, and further more preferably 0.2 or less.

[0142] The oil-in-water emulsion composition according to any one of the above <1> to <9>, wherein the HLB of the component (C) is preferably 7 or less, and more preferably 5 or less, and is preferably 1 or more, and more preferably 3 or more.

[0143] The oil-in-water emulsion composition according to any one of the above <1> to <10>, wherein the component (C) preferably contains one or two or more selected from the group consisting of a polyether-modified silicone, a glycerin fatty acid ester, an alkyl glyceryl ether, and a sorbitan fatty acid ester, more preferably contains one or two or more selected from the group consisting of a glycerin fatty acid ester and a sorbitan fatty acid ester, and particularly preferably contains a sorbitan fatty acid ester.

[0144] The oil-in-water emulsion composition according to any one of the above <1> to <11>, wherein the content of the component (C) is preferably 0.1% by mass or more, more preferably 0.4% by mass or more, particularly preferably 0.5% by mass or more, and further more preferably 0.55% by mass or more, and is preferably 3% by mass or less, more preferably 2.5% by mass or less, particularly preferably 1.8% by mass or less, and further more preferably 1.4% by mass or less, in the total composition.

[0145] The oil-in-water emulsion composition according to any one of the above <1> to <12>, wherein the mass ratio (A) / (C) of the component (A) to the component (C) is preferably 0.05 or more, more preferably 0.1 or more, particularly preferably 0.5 or more, further more preferably 0.6 or more, and further particularly preferably 0.8 or more, and is preferably 10 or less, more preferably 5 or less, particularly preferably 2.5 or less, further more preferably 2.2 or less, and further particularly preferably 1.8 or less.

[0146] The mass ratio (B) / (C) of component (B) to component (C) is preferably 0.05 or more, more preferably 1 or more, particularly preferably 3 or more, further more preferably 3.5 or more, further particularly preferably 4.5 or more, and is preferably 40 or less, more preferably 20 or less, particularly preferably 15 or less, further more preferably 12 or less, further particularly preferably 10 or less.

[0147] The content of water in component (D) is preferably 50% by mass or more, more preferably 60% by mass or more, particularly preferably 70% by mass or more, and is preferably 95% by mass or less, more preferably 90% by mass or less, particularly preferably 88% by mass or less, in the total composition.

[0148] The water-in-oil emulsion composition according to any one of <1> to <15> above preferably further contains (E) a nonionic surfactant having an HLB of 10 or more, more preferably an HLB of 11 to 16, particularly preferably an HLB of 12 to 15.

[0149] The water-in-oil emulsion composition according to <16> above, wherein the nonionic surfactant of component (E) preferably contains one or more selected from polyoxyethylene hydrogenated castor oil and polyoxyethylene sorbitan fatty acid ester, more preferably polyoxyethylene sorbitan fatty acid ester.

[0150] The water-in-oil emulsion composition according to <17> above, wherein the average addition mole number of the polyoxyethylene chain constituting the polyoxyethylene hydrogenated castor oil in the polyoxyethylene hydrogenated castor oil is preferably 25 to 100, more preferably 35 to 85, particularly preferably 45 to 75, further more preferably 55 to 65, further particularly preferably 60.

[0151] The water-in-oil emulsion composition according to <17> above, wherein the average addition mole number of the polyoxyethylene chain constituting the polyoxyethylene sorbitan fatty acid ester in the polyoxyethylene sorbitan fatty acid ester is preferably 10 to 30, more preferably 15 to 25, particularly preferably 20, and the number of carbon atoms of the alkyl group is preferably 10 to 25, more preferably 16 to 20, particularly preferably 18.

[0152] The oil-in-water emulsion composition according to any one of <16> to <19> described above, wherein the content of the component (E) is preferably 0.5% by mass or more, more preferably 1% by mass or more, particularly preferably 1.4% by mass or more, and further preferably 3% by mass or less, more preferably 2.5% by mass or less, particularly preferably 2% by mass or less, in the total composition.

[0153] The oil-in-water emulsion composition according to any one of <1> to <20> described above, wherein it preferably further contains an ionic surfactant, more preferably an anionic surfactant.

[0154] Particularly preferably, it contains one or more selected from the group consisting of N-alkanoylmethyl taurine having 12 to 22 carbon atoms or a salt thereof, and N-acyl glutamic acid having 12 to 22 carbon atoms or a salt thereof.

[0155] Further more preferably, it contains N-alkanoylmethyl taurine having 12 to 22 carbon atoms or a salt thereof; further particularly preferably, it contains N-stearyln-methyl taurine or a salt thereof.

[0156] The oil-in-water emulsion composition according to <21> described above, wherein the content of the ionic surfactant is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, particularly preferably 0.13% by mass or more, further more preferably 0.15% by mass or more, further particularly preferably 0.18% by mass or more, and further preferably 2% by mass or less, more preferably 1% by mass or less, particularly preferably 0.8% by mass or less, further more preferably 0.5% by mass or less, further particularly preferably 0.45% by mass or less, in the total composition.

[0157] The oil-in-water emulsion composition according to any one of <1> to <22> described above, wherein it preferably further contains a polyhydric alcohol, more preferably one or more selected from the group consisting of dihydric alcohol and trihydric alcohol, particularly preferably dihydric alcohol, and further more preferably one or more selected from the group consisting of 1,3-butanediol and dipropylene glycol.

[0158] The oil-in-water emulsion composition according to <23> described above, wherein the content of the polyhydric alcohol is preferably 1% by mass or more, more preferably 1.3% by mass or more, particularly preferably 1.5% by mass or more, and further more preferably 1.8% by mass or more, and further preferably 30% by mass or less, more preferably 20% by mass or less, particularly preferably 15% by mass or less, and further more preferably 12% by mass or less, in the total composition.

[0159] <25> The oil-in-water emulsion composition described in any one of the above items <23> or <24>, wherein, when the polyhydric alcohol contains a dihydric alcohol, the content of the dihydric alcohol is preferably 1% by mass or more, more preferably 1.3% by mass or more, particularly preferably 1.5% by mass or more, and further more preferably 1.8% by mass or more, and is preferably 30% by mass or less, more preferably 20% by mass or less, particularly preferably 15% by mass or less, and further more preferably 10% by mass or less, in the total composition.

[0160] <26> The oil-in-water emulsion composition described in any one of the above items <1> to <25>, wherein the Z-average particle diameter of the emulsified particles is preferably 0.05 to 0.25 μm, more preferably 0.05 to 0.2 μm, and particularly preferably 0.05 to 0.15 μm.

[0161] <27> The oil-in-water emulsion composition described in any one of the above items <1> to <26>, which is preferably an oil-in-water emulsion cosmetic.

[0162] <28> The oil-in-water emulsion composition described in any one of the above items <1> to <27>, which is used by being applied to the skin with the fingers taken from the hand.

[0163] <29> The oil-in-water emulsion composition described in any one of the above items <1> to <27>, which is used by being impregnated in a cosmetic cotton or sheet and then being wiped on the skin.

[0164] <30> A method for producing the oil-in-water emulsion composition described in any one of the above items <1> to <29>, which comprises: a step 1 of obtaining an oil phase containing component (A), component (B), and component (C); and a step 2 of mixing the oil phase obtained in step 1 with an aqueous phase containing component (D).

[0165] <31> The method for producing the oil-in-water emulsion composition described in the above item <30>, wherein the oil-in-water emulsion composition contains a dihydric alcohol, and the method comprises: a step 1 of obtaining an oil phase containing component (A), component (B), component (C), a dihydric alcohol, and a part of component (D); and a step 2 of mixing the oil phase obtained in step 1 with an aqueous phase containing the remaining part of component (D).

[0166] <32> The method for producing the oil-in-water emulsion composition described in the above item <31>, wherein the content of the dihydric alcohol is preferably 5% by mass or more, and more preferably 8% by mass or more, and is preferably 30% by mass or less, and more preferably 25% by mass or less, in the oil phase of step 1.

[0167] The method for producing the oil-in-water emulsion composition according to any one of <30> to <32> described above, wherein the content of water of component (D) in the oil phase of Step 1 is preferably 2% by mass or more, more preferably 5% by mass or more, and is preferably 10% by mass or less, more preferably 8% by mass or less.

[0168] The method for producing the oil-in-water emulsion composition according to any one of <30> to <33> described above, wherein the content of component (A) in the oil phase of Step 1 is preferably 1% by mass or more, more preferably 2% by mass or more, and is preferably 15% by mass or less, more preferably 13% by mass or less.

[0169] The method for producing the oil-in-water emulsion composition according to any one of <30> to <34> described above, wherein the content of component (B) in the oil phase of Step 1 is preferably 20% by mass or more, more preferably 30% by mass or more, and is preferably 90% by mass or less, more preferably 80% by mass or less.

[0170] The method for producing the oil-in-water emulsion composition according to any one of <30> to <35> described above, wherein the content of component (C) in the oil phase of Step 1 is preferably 2% by mass or more, more preferably 3% by mass or more, and is preferably 30% by mass or less, more preferably 20% by mass or less.

[0171] The method for producing the oil-in-water emulsion composition according to any one of <30> to <36> described above, wherein in Step 2, the oil phase obtained in Step 1 and the water phase are mixed by heating to preferably 60°C or higher, more preferably 70°C or higher, and preferably 100°C or lower.

[0172] The method for producing the oil-in-water emulsion composition according to any one of <30> to <37> described above, wherein in Step 2, the mixing mass ratio of the oil phase to the water phase (oil phase / water phase) is preferably 2 / 98 or more, more preferably 5 / 95 or more, and is preferably 40 / 60 or less, more preferably 30 / 70 or less.

[0173] An oil-in-water emulsion composition comprising the following components (A), (B), (C), and (D), and an anionic surfactant:

[0174] (A) a ceramide,

[0175] (B) an oil agent that is liquid at 25°C,

[0176] (C) a nonionic surfactant having an HLB of less than 10,

[0177] (D) water,

[0178] and the Z-average particle diameter of the emulsified particles is 0.05 to 0.3 μm.

[0179] <40> An oil-in-water emulsified composition comprising the following components (A), (B), (C), and (D):

[0180] (A) a ceramide,

[0181] (B) an oil agent that is liquid at 25°C,

[0182] (C) a nonionic surfactant having an HLB of less than 10, and

[0183] (D) water,

[0184] and the average particle diameter of the emulsified particles is 0.05 to 0.3 μm;

[0185] The component (B) contains:

[0186] (B1) a hydrocarbon oil, and

[0187] (B2) a polar oil 0.05 to 3.5% by mass;

[0188] and the mass ratio (A) / (C) of the component (A) to the component (C) is 0.05 to 10.

[0189] <41> An oil-in-water emulsified composition comprising the following components (A), (B), (C), and (D):

[0190] (A) a ceramide,

[0191] (B) an oil agent that is liquid at 25°C,

[0192] (C) a nonionic surfactant having an HLB of less than 10, and

[0193] (D) water,

[0194] and the average particle diameter of the emulsified particles is 0.05 to 0.3 μm;

[0195] further containing one or more selected from the group consisting of sodium N-stearoyl-N-methyl taurate and sodium N-stearoyl-L-glutamate: 0.05 to 2% by mass.

[0196] <42> An oil-in-water emulsified composition comprising the following components (A), (B), (C), and (D):

[0197] (A) a ceramide,

[0198] (B) an oil agent that is liquid at 25°C,

[0199] (C) a nonionic surfactant having an HLB of less than 10, and

[0200] (D) water,

[0201] and the average particle diameter of the emulsified particles is 0.05 to 0.3 μm;

[0202] Component (B) contains:

[0203] (B1) a hydrocarbon oil, and

[0204] (B2) a polar oil 0.05 to 3.5 mass%,

[0205] and the mass ratio (A) / (B) of component (A) to component (B) is 0.05 to 1.

[0206] [Examples]

[0207] [Examples 1 to 19, Comparative Examples 1 and 2]

[0208] An oil-in-water emulsified composition having the composition shown in Tables 1 to 4 was produced, the emulsified particle diameter was measured immediately after production, and the stability (45°C, 2 weeks), the skin moisturizing feel and smoothness after application to the skin using a finger, and the skin moisturizing feel and smoothness after application to the skin using a cosmetic cotton were evaluated. The results are shown in Tables 1 to 4.

[0209] In addition, the oil-in-water emulsified compositions of Examples 1 to 19 can also be used as a makeup remover.

[0210] (Production method)

[0211] (1) Component (A) to (C), a part of component (D) (0.94 mass% of the entire component (D)), component (E), stearoyl methyl taurine, and 1,3-butanediol were uniformly mixed (150 rpm) and dissolved at 80°C to produce an oil phase.

[0212] (2) The remaining water of component (D) (99.06 mass% of the entire component (D)) and glycerin were uniformly mixed and dissolved at 80°C to produce an aqueous phase.

[0213] (3) The oil phase obtained in (1) was added to the aqueous phase obtained in (2) at 80°C, mixed (300 rpm), and stirred for 10 minutes, and then cooled to room temperature (25°C) to obtain an oil-in-water emulsified composition.

[0214] (Evaluation method)

[0215] (1) Particle diameter:

[0216] Immediately after production, the Z-average particle diameter of the emulsified particles was measured at 25°C using a Zetasizer Nano Z manufactured by Malvern Co. at a dilution of 20 times for each of the oil-in-water emulsion compositions. In addition, the Z-average particle diameter here is the average of three measured values. In addition, a sample cell was used that was a product manufactured by SARTSTEDT Co. with a sample cell length of 10 x 10 x 45 mm.

[0217] (2) Presence or absence of large particles:

[0218] In the measurement results of (1), the proportion of particles of 1 μm or more was evaluated according to the following criteria from the particle size distribution.

[0219] 3: Less than 1%.

[0220] 2: 1% or more and less than 5%.

[0221] 1: 5% or more.

[0222] (3) Stability (45°C, 2 weeks):

[0223] After 20 mL of each of the oil-in-water emulsion compositions was charged into a 28 mL transparent glass container (Mighty Vial No. 6, manufactured by MARUEMU Co.), it was stored at 45°C for 2 weeks in a sealed state, and then evaluated for appearance according to the following criteria.

[0224] 5: Uniform layer without separation.

[0225] 4: Although slight turbidity appeared in the upper layer, the turbidity disappeared upon visual confirmation when the container was shaken slightly, and there were no problems in actual use.

[0226] 3: Separation of less than 1 mm appeared in the upper layer, and this was visually confirmed even when the container was shaken slightly.

[0227] 2: Separation of 1 mm or more and less than 5 mm appeared in the upper layer, and this was visually confirmed even when the container was shaken slightly.

[0228] 1: Separation of 5 mm or more appeared in the upper layer.

[0229] (4) Moist feeling and smoothness of the skin after application (application to the skin using the fingers):

[0230] Each of the oil-in-water emulsion compositions was applied to the inner side of the forearm in a range of 4 x 10 cm using the fingers by three professional panelists, and the three fingers (index finger, middle finger, and ring finger) were made to fuse with the skin for about 20 seconds. Then, the moist feeling and smoothness of the skin were evaluated according to the following criteria. The results are expressed as the total score of the three professional panelists.

[0231] (4-1) Moisturizing feeling:

[0232] 5: Clearly moisturizing.

[0233] 4: Moisturizing.

[0234] 3: Slightly moisturizing.

[0235] 2: Not so moisturizing.

[0236] 1: Clearly not moisturizing.

[0237] (4-2) Smoothness:

[0238] 5: Clearly smooth.

[0239] 4: Smooth.

[0240] 3: Slightly smooth.

[0241] 2: Not so smooth.

[0242] 1: Clearly not smooth.

[0243] (5) Moisturizing feeling and smoothness of the skin after application (to be applied to the skin by being soaked in a cosmetic cotton):

[0244] Each of the oil-in-water emulsion compositions 2 mL was taken on a cosmetic cotton (3.5 x 6.5 cm, Beauty Works Daily Cotton, manufactured by Kanebo Cosmetics Inc.) by 3 professional panelists, and was applied to the inner side of the forearm in a range of 4 x 10 cm. Then, the moisturizing feeling and smoothness of the skin were evaluated according to the same criteria as (4-1) and (4-2). The results were expressed as the total scores of the 3 professional panelists.

[0245] [Table 1]

[0246]

[0247] [Table 2]

[0248]

[0249] [Table 3]

[0250]

[0251] [Table 4]

[0252]

[0253] *1: N-(hexadecyloxyhydroxypropyl)-N-hydroxyethyl hexadecanamide, Sphingolipid E (manufactured by Kao Corporation),

[0254] *2: hydrogenated polyisobutylene, PARLEAM EX (manufactured by NOF Corporation),

[0255] *3: neopentyl glycol dicaprate, Estemol N-01 (manufactured by The Nisshin OilliO Group, Inc.),

[0256] *4: dimethylpolysiloxane, Silicone 2CS (manufactured by Shin-Etsu Chemical Co., Ltd.),

[0257] *5: sorbitan stearate (HLB: 4.7), RHEODOL SP-S10V (manufactured by Kao Corporation),

[0258] *6: polyoxyethylene (20 EO) sorbitan stearate (HLB: 14.9), RHEODOL TW-S120V (manufactured by Kao Corporation),

[0259] *7: stearoyl methyl taurate, NIKKOL SMT (manufactured by Nippon Surfactant Industries Co., Ltd.),

[0260] *8: 1,3-butanediol, 1,3-butanediol (manufactured by KH Neochem Co., Ltd.),

[0261] *9: isotridecyl isononanoate, SALACOS 913 (manufactured by The Nisshin OilliO Group, Inc.),

[0262] *10: ceramide 2, CERAMIDE TIC-001 (manufactured by Takasago Perfumery Industry Co., Ltd.),

[0263] *11: ceramide 3, CERAMIDE III (manufactured by Evonik industries AG),

[0264] *12: squalane, NIKKOL SUGARSQUALANE (manufactured by Nikko Chemicals Co., Ltd.),

[0265] *13: isononyl isononanoate, SALACOS 99 (manufactured by The Nisshin OilliO Group, Inc.),

[0266] *14: isostearyl isostearate, ISIS (manufactured by Kokyu Alcohol Kogyo Co., Ltd.),

[0267] *15: jojoba oil, refined jojoba oil (manufactured by Kao Corporation),

[0268] *16: olive oil, CROPURE OL (manufactured by Croda Japan KK),

[0269] *17: tri(caprylin • capric)glyceride, COCONAD MT (manufactured by Kao Corporation),

[0270] *18: stearic acid monoglyceride (HLB: 3.5), RHEODOL MS-60 (manufactured by Kao Corporation),

[0271] *19: stearoyl glutamic acid Na, AMISOFT HS-11P (manufactured by Ajinomoto Co., Inc.)

[0272] Formulation Examples 1 to 3 (makeup removers)

[0273] The oil-in-water emulsion cosmetic (makeup remover) shown in Table 5 was manufactured in the same manner as in Examples 1 to 19, stably emulsified and dispersed the oil phase containing the ceramide into fine particles, and was excellent in storage stability, makeup removal effect, and smooth and excellent moisturizing feeling of the skin after application.

[0274] [Table 5]

[0275]

Claims

1. An oil-in-water emulsified composition, wherein contains the following components (A), (B), (C), and (D): (A) a ceramide, (B) an oil agent that is liquid at 25°C, (C) a nonionic surfactant having an HLB of less than 10, and (D) water, and the Z-average particle diameter of the emulsified particles is 0.05 to 0.3 μm.

2. The oil-in-water emulsified composition according to claim 1, wherein further contains an anionic surfactant.

3. The oil-in-water emulsified composition according to claim 1 or 2, wherein the mass ratio (A) / (C) of component (A) to component (C) is 0.1 to 5.

4. The oil-in-water emulsified composition according to any one of claims 1 to 3, wherein the mass ratio (B) / (C) of component (B) to component (C) is 1 to 20.

5. The oil-in-water emulsified composition according to any one of claims 1 to 4, wherein component (B) contains (Bl) a hydrocarbon oil and (B2) a polar oil.

6. The oil-in-water emulsified composition according to any one of claims 1 to 5, wherein further contains (E) a nonionic surfactant having an HLB of 10 or more.

7. An oil-in-water emulsified composition, wherein contains the following components (A), (B), (C), and (D) and an anionic surfactant: (A) a ceramide, (B) an oil agent that is liquid at 25°C, (C) a nonionic surfactant having an HLB of less than 10, (D) water, and the Z-average particle diameter of the emulsified particles is 0.05 to 0.3 μm.

8. The oil-in-water emulsified composition according to any one of claims 2 to 7, wherein the anionic surfactant contains one or more selected from the group consisting of N-alkanoylmethyl taurine or a salt thereof having a carbon number of 12 to 22 and N-acyl glutamic acid or a salt thereof having a carbon number of 12 to 22.

9. The oil-in-water emulsified composition according to any one of claims 1 to 8, wherein the oil-in-water emulsified composition is a makeup remover.

10. A method of producing the oil-in-water emulsion composition according to claim 1, wherein comprises: a process 1 of obtaining an oil phase containing component (A), component (B), and component (C); and a process 2 of mixing the oil phase obtained in process 1 with an aqueous phase containing component (D).

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