Fish intestinal flora transplanting device
By designing an automated fish gut microbiota transplantation device, which employs components such as a sliding table, a fixing clamp, and a precision pushing cylinder, the problems of high stress and low efficiency in fish gut microbiota transplantation in existing technologies have been solved. This has enabled efficient and low-stress microbiota transplantation and collection, thereby improving fish survival rates.
Patent Information
- Application Number
- CN202511449987.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-11
- Publication Date
- 2026-01-23
AI Technical Summary
Existing fish gut microbiota transplantation procedures suffer from problems such as high stress, easy damage to the fish, low efficiency, and difficulty in scaling up, especially the reliance on manual operation and rigid catheters, which leads to physical damage to the gut and uneven transplantation.
A fish gut microbiota transplantation device was designed, including a fixation component and an aspiration component. It employs a sliding table, a fixing clamp, a precision pushing cylinder, an insertion tube, and a protective enlargement sleeve. Through clamping and fixing, slow movement, and precision pushing, it achieves automated microbiota transplantation and collection, reducing harm to the fish.
It improved the efficiency and survival rate of fish gut microbiota transplantation, reduced human intervention, decreased operational stress and fish damage, and achieved a more stable fixation and efficient microbiota transplantation process.
Smart Images
Figure 509B04E3-4145-471C-9E10-FDA260CBCF76 
Figure AC8E4E6E-4EAF-43BD-99BF-CDF64F2C5ACD 
Figure BFE4218C-64B9-40C6-9CD0-02D859FA93CD
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of aquaculture, and particularly relates to a fish intestinal flora transplantation device. BACKGROUND
[0002] Intestinal flora transplantation (FMT) is a new technology that transplants intestinal microflora in the body of a healthy donor into the body of a recipient, aiming to repair the intestinal micro-ecosystem and treat diseases. The technology has achieved remarkable results in human medicine and is gradually applied to the field of aquaculture to improve the intestinal health of economic fish, promote growth and enhance disease resistance. At present, fish FMT operations mostly rely on traditional manual tools such as syringes and hard catheters. The operator needs to manually fix the fish, implant the catheter into the intestinal tract of the fish, and collect the bacterial solution.
[0003] This method has many problems. First, the operation stress is large, and manual fixing and operation easily lead to violent struggle of the fish, causing strong stress reaction; the fish is damaged, and the hard catheter is easy to scratch the intestinal mucosa of the fish, causing physical damage and even secondary infection; The manual push injection dose is not the same; the research conclusion or application effect is affected; the efficiency is low, and it is extremely dependent on skilled workers, time-consuming and laborious, and difficult to be applied on a large scale.
[0004] Therefore, there is an urgent need for a special device that can automatically, finely and low-stress complete the fish intestinal flora transplantation operation. SUMMARY
[0005] In view of the defects in the prior art, the present application provides a fish intestinal flora transplantation device to improve work efficiency and reduce manual participation.
[0006] The fish intestinal flora transplantation device provided by the present application comprises a fixing assembly and a suction assembly; one end of the suction assembly is installed at one end of the fixing assembly; the fixing assembly comprises a sliding table and a fixing clamp; the fixing clamp is installed on the base of the sliding table; the fixing clamp is provided with two parts and is oppositely arranged, and one side of the two fixing clamps is hinged; the fixing clamp is provided with a fastening mold and is used for fixing fish; the suction assembly comprises a precision push cylinder, an insertion group pipe and a protective hole expansion group; the protective hole expansion group is installed on the insertion group pipe; the insertion group pipe is in transmission connection with the precision push cylinder; the insertion group pipe is located on the sliding seat of the sliding table; and the insertion group pipe can be inserted into the intestinal tract of the fish and absorb the intestinal flora of the fish.
[0007] Further, the fixing assembly further comprises support cylinders, the support cylinders are provided with two and are installed on both sides of the sliding table respectively, one end of the support cylinder is hinged with the sliding table, and the other end of the support cylinder is hinged with the fixing clamp. In actual application, the design, the support cylinder used is an electric cylinder, which realizes the opening and closing of the fixing clamp through extension and retraction, thereby conveniently realizing the fixation of the fish transplanted with intestinal flora and avoiding shaking. In actual work, the hinged design facilitates the overturning fixation, and the mechanism mainly composed of the electric cylinder also facilitates control, reduces shaking and guarantees the stability during the intestinal flora transplantation of fish.
[0008] Further, the fixing assembly further comprises a flexible bushing, the flexible bushing is installed on the inner wall of the fixing clamp, and the flexible bushing is made of silica gel material. In actual application, the flexible bushing is made of silica gel material, which effectively facilitates the abutment fixation of the fish and avoids the fish from being pressed to cause death or surface damage through the flexible feature.
[0009] Further, the fixing assembly further comprises a fixing net and a penetrating cylinder, the penetrating cylinders are provided with a plurality of and are evenly arranged on the fixing clamp, and one end of the penetrating cylinder penetrates through the flexible bushing and is connected with the fixing net. In actual application, the purpose of the design is to realize the further fixation of the fish, the design guarantees the stability and also realizes the fixation of the fish, the penetrating cylinder used is a conventional electric cylinder, the fixing net is penetrated forward through a plurality of electric cylinders, the fixation of the fish is realized and the fixation effect is maintained. Meanwhile, the output shaft of the penetrating cylinder extends backward, the fixing net is separated from the fish, in this way, the fish damage can be reduced through the fixing net, and the traditional clamp gap becomes larger after long-time use, the fish clamping is invalid, the fish shakes and the intestinal flora transplantation difficulty is increased. The double-structure combined fixation effect of the net-shaped fixation and the mold fixation is more stable, is easy to replace and is simple to operate, in this way, a more durable service life can be realized, and the cost is greatly reduced.
[0010] Further, the insertion group tube comprises a mounting frame, a syringe and a heat preservation sleeve; the mounting frame is mounted on the sliding seat of the sliding table, the syringe is detachably mounted on the mounting frame, and the heat preservation sleeve is mounted outside the syringe. In actual application, the purpose of this design is to achieve effective fixation while facilitating the disassembly and assembly of the syringe. Moreover, the heat preservation sleeve design effectively achieves a high survival rate of the bacterial flora transplantation through its low-temperature characteristics. The syringe is detachably connected with the output shaft of the precision push cylinder. In actual work, when the bacterial flora needs to be collected, the syringe is first extended into the fish intestine by sliding the sliding table, and then the precision push cylinder is started to move the output shaft away from the fish; in this way, the bacterial flora in the fish intestine can be more effectively collected. When the existing bacterial flora needs to be transplanted into the existing fish, the syringe containing the bacterial flora is simply injected into the fish intestine, that is, the precision push cylinder is moved towards the fish to achieve the work of transplanting and injecting the bacterial flora.
[0011] Further, the protective reaming set is mounted on the needle of the syringe, and comprises a silica gel sleeve and an inner heating element; the silica gel sleeve is mounted on the needle of the syringe and covers the needle of the syringe; the inner heating element is located in the silica gel sleeve and close to the direction of the needle of the syringe. In actual application, the purpose of this design is to achieve thermal expansion and cold contraction, and to expand the hole during the collection of intestinal flora, that is, to dilate the anus of the fish, which facilitates the collection of intestinal flora. Moreover, due to the silica gel characteristics, the dilated radius is limited, and the flexible characteristics of silica gel greatly meet the actual application.
[0012] Further, the silica gel sleeve is provided with a cavity layer and a flexible support layer, and the inner heating element is located in the cavity layer; the flexible support layer is arranged on the cavity layer.
[0013] Further, the inner heating element is an electric heating ring. In actual application, the cavity layer design is used to facilitate the installation of the electric heating ring in the cavity layer, and to achieve heat transfer in space, avoid rapid heating and damage to the bacterial flora, and avoid the influence of high temperature on the survival rate of the bacterial flora during collection.
[0014] From the above technical solution, the fish intestinal flora transplantation device provided by the application has the following advantages: In actual application, the design adopts the design idea of clamping fixation and bacterial flora transplantation by suction, which can effectively solve the bacterial flora transplantation work of fish. The combination of the sliding table and the fixed clamp realizes slow movement to the suction assembly after clamping, which facilitates the subsequent precise transplantation work. Meanwhile, in order to facilitate transplantation, a combination of a precision push cylinder, an insertion group tube and a protective reaming set is adopted, wherein the precision push cylinder serves as a power source to push the insertion group tube into the intestinal tract of the fish; Moreover, the device can not only achieve transplantation, but also collection, with the intestinal tract as the inlet and outlet, replacing the traditional operation of transplanting the flora from the oral cavity of the fish, which can greatly reduce the damage to the oral cavity and further improve the survival rate of the fish during the transplantation process. Moreover, the precision push cylinder is an electric cylinder equipment mainly composed of a precision screw rod mechanism, which effectively improves the work efficiency and replaces manual operation to achieve automation. BRIEF DESCRIPTION OF DRAWINGS
[0015] In order to more clearly illustrate the specific embodiments of the present application, the drawings required to be used in the specific embodiments or prior art description will be briefly introduced below. In all the drawings, the elements or parts are not necessarily drawn according to the actual scale.
[0016] Figure 1 A front view of a fish intestinal flora transplantation device according to an embodiment of the present application is provided. Figure 2 A schematic view of a fixing assembly in the present application is provided. Figure 3 A schematic view of the installation structure of a counter-advancing cylinder in the fixing clamp in the fixing assembly in the present application is provided. Figure 4 A schematic view of the installation structure of a counter-advancing cylinder in the fixing clamp in the fixing assembly in the present application is provided. Figure 1 A schematic view of the installation structure of a counter-advancing cylinder in the fixing clamp in the fixing assembly in the present application is provided. Figure 5 A front view of a fixing clamp in the present application is provided. Reference signs: Fixing assembly 1, suction assembly 2, sliding table 11, fixing clamp 12, supporting cylinder 13, flexible bushing 14, fixing net 15, counter-advancing cylinder 16, precision push cylinder 21, insertion group tube 22, mounting rack 221, syringe 222, heat preservation sleeve 223, protective reaming set 23, silica gel outer sleeve 231, cavity layer 2311, flexible support layer 2312, internal heating element 232. DETAILED DESCRIPTION
[0017] The embodiments of the technical solutions of the present application will be described in detail below with reference to the drawings. The following embodiments are only used to more clearly illustrate the technical solutions of the present application, and therefore only serve as examples, but cannot limit the protection scope of the present application.
[0018] The embodiments are basically as shown in the drawings: Figures 1 to 5 As Figure 1 - Figure 5 The fish intestinal flora transplantation device provided by the embodiment can improve work efficiency and reduce manual participation.
[0019] The fish intestinal flora transplantation device provided by the embodiment can improve work efficiency and reduce manual participation. The fish intestinal flora transplantation device provided by the embodiment can improve work efficiency and reduce manual participation. In actual application, the design adopts the design idea of clamping fixation and subsequent absorption of flora transplantation. This method can effectively solve the flora transplantation work of fish. The combination design of the sliding table 11 and the fixed clamp 12 realizes slow movement to the absorption assembly 2 after clamping, which facilitates subsequent precise transplantation work. In order to facilitate transplantation, the combination design of the precision push cylinder 21, the insertion group pipe 22 and the protective hole expansion group 23 is also adopted. The precision push cylinder 21 serves as a power source to push the insertion group pipe 22 into the intestinal tract of fish. Moreover, the device can not only realize transplantation but also realize collection. The intestinal tract serves as an inlet and an outlet, replacing the traditional flora transplantation operation through the oral cavity of fish. In this way, the damage to the oral cavity can be greatly reduced, and the survival rate of the transplantation process of fish is further improved. Moreover, the precision push cylinder 21 is an electric cylinder equipment mainly based on a precision lead screw mechanism, which effectively improves the work efficiency and replaces manual operation to realize automation.
[0020] In the embodiment, in order to realize further automation operation, the fixed assembly 1 further includes support cylinders 13. The support cylinders 13 are provided in two places and are respectively installed on both sides of the sliding table 11. One end of the support cylinder 13 is hinged to the sliding table 11, and the other end of the support cylinder 13 is hinged to the fixed clamp 12. In actual application, the support cylinder 13 is an electric cylinder, which realizes the opening and closing of the fixed clamp 12 through stretching and contracting, thereby facilitating the fixation of fish for transplantation of intestinal flora and avoiding shaking of the fish. In actual work, the hinged design facilitates the overturning fixation, and the mechanism mainly based on the electric cylinder also facilitates control, reduces shaking and ensures stability during the fish intestinal flora transplantation.
[0021] Meanwhile, in order to reduce the internal damage of the fish, the fixing assembly 1 further comprises a flexible bushing 14 mounted on the inner wall of the fixing clamp 12 in the embodiment. The flexible bushing 14 is made of silica gel material. In actual application, the flexible bushing 14 is made of silica gel material, which effectively facilitates the abutting and fixing of the fish and avoids the fish being pressed to death or surface damage through the flexible feature.
[0022] Moreover, in order to prolong the actual service life, the fixing assembly 1 further comprises a fixing net 15 and a penetrating cylinder 16 in the embodiment. The penetrating cylinder 16 is provided with a plurality of penetrating cylinders and is uniformly arranged on the fixing clamp 12 and connected with the fixing net 15 through one end penetrating the flexible bushing 14. In actual application, the purpose of the design is to further fix the fish, which further guarantees the stability and realizes the fixation of the fish through the penetrating cylinder 16 designed as a conventional electric cylinder. The output shaft of the penetrating cylinder 16 extends rearward, the fixing net 15 is separated from the fish, so that the fish damage can be reduced through the fixing net 15. The traditional clamping design of silica gel or other soft materials causes the gap of the clamp to become larger after a long time of use, which causes the clamping of the fish to be invalid, causes the fish to shake and increases the difficulty of bacteria transplantation. The double-structure combination of the net-shaped fixation and the mold fixation of the device has the advantages of stable fixation, easy replacement and simple operation, which can realize a more durable service life and greatly reduce the cost.
[0023] Meanwhile, in order to facilitate collection and transplantation, the insertion group tube 22 comprises a mounting frame 221, a syringe 222 and a heat preservation sleeve 223 in the embodiment. The mounting frame 221 is mounted on the sliding seat of the sliding table 11, the syringe 222 is detachably mounted on the mounting frame 221, and the heat preservation sleeve 223 is mounted outside the syringe 222. In actual application, the purpose of the design is to effectively fix and facilitate the disassembly and assembly of the syringe 222. Moreover, the heat preservation sleeve 223 is designed to effectively realize the high survival rate of bacteria transplantation through the low-temperature feature. The syringe 222 and the output shaft of the precision push cylinder 21 are detachably connected. In actual work, when the bacteria are collected, the syringe 222 is inserted into the fish intestine through the sliding of the sliding table 11, and then the precision push cylinder 21 is started to move the output shaft away from the fish. In this way, the bacteria in the fish intestine can be collected. When the existing bacteria are transplanted into the existing fish, the syringe 222 containing the bacteria is injected into the fish intestine, that is, the precision push cylinder 21 moves towards the fish to realize the work of transplanting and injecting the bacteria.
[0024] And in order to further protect the fish intestine, in the embodiment, the protective reaming set 23 is installed on the needle of the injector 222, the protective reaming set 23 comprises a silica gel sheath 231 and an inner heating element 232; the silica gel sheath 231 is installed on the needle of the injector 222 and covers the needle of the injector 222; the inner heating element 232 is located in the silica gel sheath 231 and close to the direction of the needle of the injector 222. In actual application, the purpose of the design is to realize thermal expansion and contraction; and then realize the reaming in the process of collecting intestinal flora, that is, the anus of the fish is expanded, so that the intestinal flora is collected conveniently; and due to the silica gel characteristics, the expansion of the expansion radius is limited; in addition, the flexible characteristics of the silica gel greatly meet the actual application.
[0025] At the same time, in order to realize higher survival rate, in the embodiment, the silica gel sheath 231 is provided with a cavity layer 2311 and a flexible support layer 2312, the inner heating element 232 is located in the cavity layer 2311; the flexible support layer 2312 is arranged on the cavity layer 2311. Specifically, the inner heating element 232 is an electric heating ring. In actual application, the design of the cavity layer 2311 is to facilitate the installation of the electric heating ring in the cavity layer 2311, and on the other hand, it also realizes heat transfer in space, avoids rapid heating and causes damage to the flora; at the same time, it can also avoid the influence of high temperature on the survival rate of the flora during collection.
[0026] In summary, the fish intestinal flora transplantation device can effectively realize the transplantation of flora, and can also realize the collection of flora, greatly improving the application range, so that the device is suitable for industry promotion.
[0027] In the specification of the present application, a large number of specific details are described. However, it can be understood that the embodiments of the present application can be practiced without these specific details. In some examples, well-known methods, structures and techniques are not shown in detail in order not to obscure the understanding of the present specification.
[0028] The above embodiments are only used to illustrate the technical solutions of the present application, but not limit it; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: it can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement to part or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should be covered in the scope of the claims and the specification of the present application.
Claims
1. A fish gut microbiota transplantation device, characterized in that, include: A fixing component and a suction component; one end of the suction component is mounted on one end of the fixing component; The fixing assembly includes a slide and a fixing clamp; the fixing clamp is mounted on the base of the slide; the fixing clamp has two locations, which are arranged opposite each other, and one side of the two fixing clamps is hinged; the fixing clamp has a fastening mold and is used to fix the fish. The suction assembly includes a precision push cylinder, an insertion tube, and a protective expansion sleeve. The protective expansion sleeve is installed on the insertion tube. The insertion tube is connected to the precision push cylinder. The insertion tube is located on the slide of the slide table. It can be inserted into the fish's intestine and absorb the fish's intestinal flora.
2. The fish intestinal flora transplantation device according to claim 1, characterized in that, The fixing assembly also includes a support cylinder, which has two locations and is respectively installed on both sides of the slide. One end of the support cylinder is hinged to the slide, and the other end of the support cylinder is hinged to the fixing clamp.
3. The fish intestinal flora transplantation device according to claim 1, characterized in that, The fixing component also includes a flexible bushing, which is mounted on the inner wall of the fixing clamp; the flexible bushing is made of silicone material.
4. The fish intestinal flora transplantation device according to claim 3, characterized in that, The fixing component also includes a fixing net and a pressing cylinder; multiple pressing cylinders are provided and evenly distributed on the fixing clamp, and one end of each cylinder passes through the flexible bushing and is connected to the fixing net.
5. The fish intestinal flora transplantation device according to claim 1, characterized in that, The insertion tube includes a mounting bracket, a syringe, and an insulation sleeve; the mounting bracket is mounted on the slide of the slide table, the syringe is detachably mounted on the mounting bracket, and the insulation sleeve is mounted on the outside of the syringe.
6. The fish intestinal flora transplantation device according to claim 5, characterized in that, The protective enlarger sleeve is installed on the needle of the syringe. The protective enlarger sleeve includes a silicone outer sleeve and an inner heating element. The silicone outer sleeve is installed on the needle of the syringe and covers the needle of the syringe. The inner heating element is located inside the silicone outer sleeve and is close to the needle of the syringe.
7. A fish intestinal flora transplantation device according to claim 6, characterized in that, The silicone outer casing has a cavity layer and a flexible support layer, with the internal heating element located inside the cavity layer; the flexible support layer is disposed on the cavity layer.
8. A fish intestinal flora transplantation device according to claim 6, characterized in that, The internal heating element is an electric heating coil.