Whitening and spot-fading cream and preparation method thereof
By using a combination of niacinamide and specific plant extracts in the whitening and spot-fading cream, along with ingredients such as hydroxypropyl cyclodextrin and sophora flavescens root extract, the irritation and poor efficacy issues of existing products are resolved, providing a highly effective and gentle whitening and spot-fading solution.
Patent Information
- Application Number
- CN202511676368.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-17
- Publication Date
- 2026-01-30
AI Technical Summary
Existing whitening and freckle-removing products often illegally add heavy metals or reduce the concentration of active ingredients in pursuit of results, leading to skin irritation and poor efficacy, failing to simultaneously meet the requirements of rapid whitening and gentleness.
Niacinamide is used as the main whitening and spot-fading agent, combined with specific proportions of Spirulina macrophylla extract, Portulaca oleracea extract, Morus alba root bark extract, cactus extract and jujube fruit extract, and hydroxypropyl cyclodextrin is added as a stabilizer. Through pre-combination treatment, it is combined with specific proportions of Sophora flavescens root extract and α-arbutin to form a uniform and stable emulsion system.
It achieves noticeable brightening and spot-fading effects within 2 weeks of use, is gentle on the skin, provides long-lasting whitening without irritation, and is suitable for various skin types.
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Abstract
Description
Technical Field
[0001] This invention relates to the field of skincare products, and in particular to a whitening and spot-fading cream and its preparation method. Background Technology
[0002] As people place increasing importance on appearance management, skin whitening and spot-removing skincare products have gradually become a popular category in the market. Consumer demand for improving facial pigmentation and brightening skin tone continues to grow, driving the rapid development of these products. Currently, the market offers a wide variety of whitening and spot-removing cream brands and products in different forms, covering different price ranges and efficacy claims to meet diverse consumer needs.
[0003] However, existing whitening and freckle-removing products often face the problem of not being able to achieve multiple benefits simultaneously. On the one hand, some unscrupulous merchants, in pursuit of so-called "rapid whitening and freckle-removing" effects, illegally add heavy metals such as mercury and lead, as well as prohibited substances such as glucocorticoids. Although these ingredients may make the skin appear whiter in the short term, they are highly irritating and leave residues. With prolonged use, they can easily accumulate on the user's skin or in the body, leading to damage to the stratum corneum and causing a series of skin problems such as pigmentation and chronic inflammation. On the other hand, some whitening and freckle-removing products emphasize a gentle and non-irritating freckle-removing effect. However, in pursuit of gentleness, these products often reduce the concentration of effective freckle-removing ingredients or choose freckle-removing ingredients with slower effects. As a result, users need to use them consistently for a long time to see any improvement. However, during the long waiting period, if users experience anxiety due to the lack of timely control of freckles, or are affected by external environmental factors, the freckles may worsen or recur due to endocrine disorders, directly affecting the product's whitening and freckle-removing effect. Summary of the Invention
[0004] In order to improve the skin-friendly properties of whitening and freckle-removing products while ensuring their whitening and freckle-removing effects and reducing their irritation to the user's skin, this application provides a whitening and freckle-removing cream and its preparation method.
[0005] Firstly, the whitening and spot-fading cream provided in this application adopts the following technical solution: A whitening and spot-fading cream comprises 1.5-2.5 wt% whitening and spot-fading agent, 3.4-4.6 wt% skin conditioning agent, 3-3.8 wt% plant extract, 4.6-5.2% emulsifier, 0.42-0.5 wt% preservative, 16.6-17 wt% moisturizer, 3.2-3.5 wt% skin moisturizer, 3.6-4 wt% homogenizer, 1.8-2 wt% lubricant, 1-1.2 wt% antioxidant, 0.2-0.3 wt% thickener, 0.1-0.15 wt% fragrance, and the balance being solvent. The whitening and spot-fading agent includes at least niacinamide; The skin conditioning agent comprises at least 0.25-0.3 wt% allantoin, 0.4-0.5 wt% glycyrrhizin, 0.35-0.48 wt% papain, 0.25 wt%-0.32 wt% phenoxyethanol, and 2-2.2 wt% 1-methylhydantoin-2-imide; The plant extract comprises at least 1.8-2 wt% Spirulina macrophylla extract, 0.5-0.6 wt% Portulaca oleracea extract, 0.1-0.3% Morus alba root bark extract, 0.1-0.3% Prickly pear cactus extract, and 0.05-0.2 wt% Jujube fruit extract; The emulsifier includes a hydrophilic emulsifier and a lipophilic emulsifier, wherein the mass ratio of the hydrophilic emulsifier to the lipophilic emulsifier is (1-1.2):(3.6-4). The preservatives include bis(hydroxymethyl)imidazolidinyl urea and hydroxyphenyl ester preservatives, wherein the mass ratio of bis(hydroxymethyl)imidazolidinyl urea to hydroxyphenyl ester preservatives is 1:(1.5-1.8).
[0006] By adopting the above technical solution, the whitening and spot-fading cream uses niacinamide as the main whitening and spot-fading agent, combined with plant extracts such as Spirulina macrophylla extract, Portulaca oleracea extract, mulberry root bark extract, cactus extract, and jujube fruit extract in specific proportions. This produces a whitening and spot-fading cream with good whitening and spot-fading effects, comfortable to use, and non-irritating. Significant brightening and spot-fading effects are visible after two weeks of use. Niacinamide not only effectively reduces the binding efficiency of tyrosinase to melanosomes, indirectly reducing the catalytic activity of tyrosinase on tyrosine, but also inhibits the activity of PAR-2 receptors, cutting off the signal transmission of "external stimulation-melanin production," reducing melanin deposition caused by external factors, and achieving a long-lasting whitening and spot-fading effect. The specific plant extracts not only synergistically enhance the skin's antioxidant capacity and inhibit tyrosinase activity, improving its whitening and spot-fading effect, but also moisturize, reduce inflammation, and nourish the skin, effectively reducing skin dryness caused by the high niacinamide content, thus improving the gentleness and comfort of the whitening and spot-fading cream.
[0007] Optionally, the whitening and spot-fading agent is specifically a composition comprising niacinamide, ferulic acid, and tranexamic acid, wherein the mass ratio of niacinamide, ferulic acid, and tranexamic acid is (1-1.2):(0.6-0.9):(0.1-0.2). The whitening and spot-fading cream also contains 1.8-2 wt% of a stabilizer, specifically hydroxypropyl cyclodextrin, and the whitening and spot-fading agent needs to be pre-combined with the stabilizer before being added.
[0008] By adopting the above technical solution, with nicotinamide, ferulic acid and tranexamic acid as whitening and spot-fading agents, and adding a certain proportion of hydroxypropyl cyclodextrin as a stabilizer, and pre-treating the two together, it can not only effectively improve the obvious irritation caused by the addition of ferulic acid and tranexamic acid, but also fully exert the brightening, whitening and spot-fading effects of the whitening and spot-fading agents, which is conducive to further improving the user experience of the whitening and spot-fading cream.
[0009] Optionally, the pre-combination process includes the following steps: A1. Weigh out nicotinamide and ferulic acid according to the proportion, add them to anhydrous ethanol at 45-50℃ and dissolve them completely to obtain a mixed ethanol solution; separately weigh out tranexamic acid and hydroxypropyl cyclodextrin according to the proportion, add them to distilled water and dissolve them completely to obtain a mixed aqueous solution; A2. Heat the mixed aqueous solution to 45-50℃, stir magnetically, and add the mixed ethanol solution dropwise. After the addition is complete, keep warm and continue stirring for 30-40 minutes to obtain a eutectic solution. Then heat to 55-60℃ and vacuum dry to obtain a pre-combined whitening and spot-fading agent.
[0010] By employing the above technical solution, hydroxypropyl cyclodextrin can fully encapsulate niacinamide, ferulic acid, and tranexamic acid. This not only effectively reduces the direct contact between the three components in the whitening and spot-fading agent and external oxygen and light, but also prevents adverse reactions between niacinamide and the other two acidic components during long-term storage, thus improving the overall stability and long-term shelf life of the whitening and spot-fading cream. Secondly, the encapsulation effect of hydroxypropyl cyclodextrin significantly reduces the free concentration of the three components in the whitening and spot-fading cream, directly reducing the osmotic pressure on the skin during their direct action and lowering the irritation of the whitening and spot-fading agent. Furthermore, due to the good compatibility of the hydrophilic shell of hydroxypropyl cyclodextrin with the stratum corneum of the skin, it can efficiently carry the encapsulated whitening and spot-fading agent to the dermis and release it slowly, allowing more whitening and spot-fading ingredients to reach their target sites and exert their effects, further improving the whitening and spot-fading performance of the whitening and spot-fading agent.
[0011] Optionally, the plant extract may further include 0.05-0.1 wt% Sophora flavescens root extract and 0.1-0.2 wt% α-arbutin.
[0012] By adopting the above technical solutions, not only can the whitening and spot-fading effects of the whitening and spot-fading cream be further improved, but the comfort of using the whitening and spot-fading cream is also not significantly affected.
[0013] Optionally, the hydrophilic emulsifier is at least one of sodium polyacrylate, C13-14 isoparaffin, and lauryl ether-7.
[0014] Optionally, the lipophilic emulsifier is at least one of glyceryl stearate, polyethylene glycol glyceryl stearate, and cetearyl alcohol.
[0015] Optionally, the hydroxyphenyl ester preservative is at least one of methylparaben, ethylparaben, and propylparaben.
[0016] Optionally, the moisturizer is at least one of glycerin, propylene glycol, sodium hyaluronate, and panthenol.
[0017] Optionally, the emollient is at least one of caprylic / capric triglyceride, cyclohexylsiloxane, and cyclopentamethoxysiloxane.
[0018] Secondly, the preparation method of the whitening and spot-fading cream provided in this application adopts the following technical solution: A method for preparing a whitening and spot-fading cream includes the following steps: S1. Take 90% solvent, allantoin, panthenol, Spirulina macrophylla extract and Portulaca oleracea extract as ingredient A, and add them to the aqueous phase pot in sequence. Heat to 80-85℃ while stirring. Pre-mix the humectant and thickener thoroughly as ingredient B, and then add them to the aqueous phase pot. Continue stirring and mix ingredient A and ingredient B thoroughly to obtain the aqueous phase material. S2. Add the lipophilic emulsifier, homogenizer, antioxidant, and hydroxyphenyl ester preservative as material C to the oil phase pot in sequence, heat to 80-85℃ with stirring, and mix evenly to obtain the oil phase material; S3. Pump the aqueous phase material into the vacuum emulsification pot, homogenize for 1-2 minutes, adjust the stirring speed to 1000-1200 r / min, then pump in the oil phase material and maintain vacuum homogenization for 4-5 minutes. S4. Turn on the cooling water and cool to 60-65℃. Add 8% solvent, whitening and spot-fading agent, aqueous emulsifier, emollient, and the remaining skin conditioning agent and plant extract as ingredient D in sequence, and homogenize for 4-5 minutes. S5. Continue cooling to 45-50℃, add the remaining solvent, bis(hydroxymethyl)imidazolidinyl urea and fragrance, continue homogenization for 1-2 minutes, cool to below 38℃ and discharge to obtain a whitening and spot-fading cream.
[0019] By adopting the above technical solution, the components can be effectively mixed evenly, which is conducive to obtaining a uniform and stable emulsion system. This not only effectively ensures the whitening and spot-fading cream's effect, but also helps improve the system's durability, giving the whitening and spot-fading cream better long-term storage properties.
[0020] In summary, the technical solution of this application has at least one of the following beneficial effects: 1. By using niacinamide in combination with specific amounts of Spirulina macrophylla extract, Portulaca oleracea extract, mulberry root bark extract, cactus extract, and jujube fruit extract, a whitening and spot-fading cream with good whitening and spot-fading effects, comfortable to use, and non-irritating can be prepared, and a significant brightening and spot-fading effect can be seen after 2 weeks of use.
[0021] 2. By using nicotinamide, ferulic acid, and tranexamic acid as whitening and spot-fading agents, combined with a certain proportion of hydroxypropyl cyclodextrin as a stabilizer, and pre-treating the two together, it can not only effectively improve the obvious irritation caused by the addition of ferulic acid and tranexamic acid, but also fully exert the brightening, whitening, and spot-fading effects of the whitening and spot-fading agents, which is conducive to further improving the user experience of the whitening and spot-fading cream.
[0022] 3. By adding a certain amount of Sophora flavescens root extract and α-arbutin, not only can the whitening and spot-fading effects of the whitening and spot-fading cream be further improved, but the comfort of using the whitening and spot-fading cream is also not significantly affected. Detailed Implementation
[0023] The present application will be further described in detail below with reference to the embodiments and preparation examples. Example
[0024] The whitening and spot-fading cream disclosed in Examples 1-3 of this application comprises the following raw materials in the mass ratio (%) shown in Table 1: Table 1
[0025] This application also discloses a method for preparing a whitening and spot-fading cream in [Example 1]-[Example 3], specifically including the following steps: S1. Take 90% solvent, allantoin, panthenol, Spirulina macrophylla extract and Portulaca oleracea extract as ingredient A, and add them to the aqueous phase pot in sequence. Heat to 80-85℃ while stirring. Pre-mix the humectant and thickener thoroughly as ingredient B, and then add them to the aqueous phase pot. Continue stirring and mix ingredient A and ingredient B thoroughly to obtain the aqueous phase material. S2. Add the lipophilic emulsifier, homogenizer, antioxidant, and hydroxyphenyl ester preservative as material C to the oil phase pot in sequence, heat to 80-85℃ with stirring, and mix evenly to obtain the oil phase material; S3. Pump the aqueous phase material into the vacuum emulsification pot, homogenize for 1 min, adjust the stirring speed to 1000 r / min, then pump in the oil phase material, maintain the vacuum less than -0.05 MPa and homogenize for 4 min. S4. Turn on the cooling water and cool to 60-65℃. Add 8% solvent, whitening and spot-fading agent, aqueous emulsifier, emollient, and the remaining skin conditioning agent and plant extract as ingredient D in sequence, and homogenize for 5 minutes. S5. Continue cooling to 45-50℃, add the remaining solvent, bis(hydroxymethyl)imidazolidinyl urea and fragrance, continue homogenization for 1 minute, cool to below 38℃ and discharge to obtain a whitening and spot-fading cream.
[0026] The whitening and spot-fading cream disclosed in Examples 4-7 of this application differs from that in Example 1 in the content of the whitening and spot-fading agent components, stabilizers, and solvents. In Examples 4-7, the whitening and spot-fading agent of the whitening and spot-fading cream includes the raw materials in the following mass ratio (%) as shown in Table 2: Table 2
[0027] In particular, the whitening and spot-fading agents in [Example 5]-[Example 7] of this application need to be pre-combined with stabilizers before addition. The specific pre-combination treatment includes the following steps: A1. Weigh out nicotinamide and ferulic acid according to the proportion, add them to anhydrous ethanol at 45°C and dissolve them completely to obtain a mixed ethanol solution; separately weigh out tranexamic acid and hydroxypropyl cyclodextrin according to the proportion, add them to distilled water and dissolve them completely to obtain a mixed aqueous solution; A2. Heat the mixed aqueous solution to 45°C, stir magnetically, and add the mixed ethanol solution dropwise. After the addition is complete, keep warm and continue stirring for 30-40 minutes to obtain a eutectic solution. Then heat to 60°C and vacuum dry to obtain the pretreated whitening and spot-fading agent.
[0028] The whitening and spot-fading cream disclosed in Examples 8-9 of this application differs from that in Example 5 in the composition of the plant extract and the content of the solvent. In Examples 8-9, the plant extract and solvent of the whitening and spot-fading cream include the following raw materials in the mass ratio (%) shown in Table 3: Table 3
[0029]
Example 10
[0030]
Example 11
[0031] Comparative Example 1 A whitening and spot-fading cream, which differs from [Example 1] in that: the Spirulina macrophylla extract uses an equal mass of Chlorella extract.
[0032] Comparative Example 2 A whitening and spot-fading cream differs from [Example 1] in that: the purslane extract is replaced with an equal mass of centella asiatica extract.
[0033] Comparative Example 3 A whitening and spot-fading cream differs from [Example 1] in that: the mulberry root bark extract, cactus extract, and jujube fruit extract are replaced with solvents of equal mass. Performance test data
[0034] Subject selection: 280 subjects were selected and divided into 14 groups of 20 people each. The 14 groups corresponded to the whitening and spot-fading creams prepared in the test examples and comparative examples, respectively. When grouping, it was necessary to fully consider different skin types (dry, oily, combination), the evenness of distribution of age within 18-60 years, and different types of pigmentation (freckles, melasma, sun spots, age spots, etc.) of healthy men or women. In addition, before the test, the subjects were required not to have used other whitening and spot-fading products in the past 3 months, and had no history of skin diseases or cosmetic allergies.
[0035] Each group of subjects applied the whitening and spot-fading cream at roughly the same time every morning and evening. Before each use, subjects were required to cleanse their faces and rest for at least 15 minutes as instructed. Each application involved taking approximately 0.5g of the product and applying it evenly to the entire face. The use was continued for 8 weeks. During the test, makeup and the use of other products with whitening and spot-fading effects were minimized as much as possible.
[0036] 1. Whitening and Spot-Fading Effect Test: Using a skin colorimeter (Minolta CM-26D), the skin brightness (L value) and pigment content (M value) of the subjects' faces with the same coating area and the neck without coating area were measured before the test and after 2, 4, and 8 weeks of product use. Skin brightness was measured mainly on facial areas without obvious spots, while pigment content was measured mainly on facial areas with obvious spots. Each test point on each test area was tested 4 times, and the average value was taken as the specific data for the corresponding area. Finally, the average value of the skin brightness change rate and the spot pigment content change rate of each group of subjects was calculated and recorded.
[0037] The formula for calculating the rate of change in skin brightness is as follows: △L = (Facial skin brightness - Neck skin brightness) / Neck skin brightness * 100% The formula for calculating the rate of change in pigment content is as follows: △L = (Pre-test melanin content - melanin content) / Pre-test melanin content * 100% 2. Irritation Test: Each time the whitening and spot-fading cream was applied, the subjects subjectively rated the level of irritation based on their own skin sensations. The rating was divided into severe irritation (discontinue use and seek medical attention), moderate irritation (requires measures to alleviate), mild irritation (can be alleviated on its own), and no irritation. Subjects rated their subjective irritation level on a scale of 1 to 10, with 1 representing severe irritation (discontinue use and seek medical attention) and 10 representing no irritation. The total average score for each group of subjects was calculated and recorded, and the result was rounded to one decimal place. In addition, it was observed whether redness, swelling, itching, stinging, peeling, etc. appeared on the face during long-term (8 weeks) use. If these phenomena occurred, the number of people experiencing them was recorded in the remarks, and the test for that person was discontinued.
[0038] Table 4. Test data on the whitening and spot-fading performance of the whitening and spot-fading cream.
[0039] Table 5 Irritation Test Data for Whitening and Spot-Fading Creams
[0040] Based on the data from Examples 1 and Comparative Examples 1-3, and combined with Tables 4 and 5, it can be seen that by using niacinamide as the main whitening and spot-fading agent, and combining it with plant extracts in specific proportions of Spirulina macrophylla extract, Portulaca oleracea extract, Morus alba root bark extract, cactus extract, and jujube fruit extract, a whitening and spot-fading cream with good whitening and spot-fading effects, comfortable to use, and non-irritating, can be prepared. Significant brightening and spot-fading effects are observed after two weeks of use. Through the action of niacinamide, the whitening and spot-fading cream effectively inhibits melanin formation in the skin, achieving the effects of brightening skin tone and fading dark spots. Simultaneously, the specific plant extracts not only synergistically enhance the skin's antioxidant capacity and inhibit tyrosinase activity, improving its whitening and spot-fading effects, but also moisturize, reduce inflammation, and nourish the skin, effectively reducing skin dryness caused by the high niacinamide content, thus improving the gentleness and comfort of the whitening and spot-fading cream.
[0041] Combining the data from Examples 1 and 4-7 with those from Tables 4 and 5, it is evident that when ferulic acid and tranexamic acid are used alone in combination with niacinamide as whitening and spot-removing agents, while the skin brightening effect is significantly increased, the spot-fading effect decreases, and the irritation of the whitening and spot-fading cream is also increased, resulting in reduced user comfort. However, when niacinamide, ferulic acid, and tranexamic acid are used as whitening and spot-fading agents, adding a certain proportion of hydroxypropyl cyclodextrin as a stabilizer to the system, and pre-mixing the two together, not only can the significant irritation caused by the addition of ferulic acid and tranexamic acid be effectively improved, but the whitening and spot-fading agents can also be fully utilized, which is beneficial to further improving the user experience of the whitening and spot-fading cream. In addition, when the mass ratio of niacinamide, ferulic acid, and tranexamic acid is (1-1.2):(0.6-0.9):(0.1-0.2), the overall performance of the whitening and spot-fading cream is better, which is more conducive to balancing the whitening and spot-fading effect and user comfort.
[0042] Combining the data from Examples 5 and 8-11 with those from Tables 4 and 5, it is evident that adding a specific proportion of Sophora flavescens root extract and α-arbutin to the system further enhances the whitening and spot-fading effect of the whitening and spot-fading cream, while having little impact on the comfort of use. This is likely because Sophora flavescens root extract and α-arbutin not only possess excellent melanin-inhibiting, antioxidant, and whitening effects, but the matrine in Sophora flavescens root extract can also reduce histamine release, alleviate skin redness and itching, and help reduce the slight irritation that α-arbutin may cause. Furthermore, they have skin-repairing effects, promoting keratinocyte proliferation, repairing and enhancing the skin barrier function, and improving skin tolerance. Therefore, when used synergistically, the overall gentleness is high, making it more suitable for sensitive skin, dry skin, and even damaged skin. However, when either Sophora flavescens root extract or α-arbutin is replaced in equal amounts with other plant extracts that have similar effects, the improvement in the overall performance of the whitening and spot-fading agent significantly decreases.
[0043] This specific embodiment is merely an explanation of this application and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this specific embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of the claims of this application.
Claims
1. A skin whitening and freckle lightening cream, characterized by comprising: The composition comprises 1.5-2.5wt% whitening and freckle-removing agent, 3.4-4.6wt% skin conditioning agent, 3-3.8wt% plant extract agent, 4.6-5.2% emulsifier, 0.42-0.5wt% preservative, 16.6-17wt% moisturizer, 3.2-3.5wt% emollient, 3.6-4wt% homogenizing agent, 1.8-2wt% slip agent, 1-1.2wt% antioxidant, 0.2-0.3wt% thickening agent, 0.1-0.15wt% fragrance, and the rest is solvent; The whitening and freckle-removing agent at least comprises niacinamide; The skin conditioning agent at least comprises 0.25-0.3wt% allantoin, 0.4-0.5wt% glycyrrhizin flavonoids, 0.35-0.48wt% papain, 0.25wt%-0.32wt% phenoxyethanol, and 2-2.2wt% 1-methylhydantoin-2-imide; The plant extract agent at least comprises 1.8-2wt% extremely large spirulina extract, 0.5-0.6wt% purslane extract, 0.1-0.3% mulberry root extract, 0.1-0.3% cactus extract, and 0.05-0.2wt% jujube fruit extract; The emulsifier comprises hydrophilic emulsifier and oleophilic emulsifier, and the mass ratio of the hydrophilic emulsifier to the oleophilic emulsifier is (1-1.2):(3.6-4); The preservative comprises bis(hydroxymethyl)imidazolidinyl urea and hydroxybenzoic ester preservative, and the mass ratio of the bis(hydroxymethyl)imidazolidinyl urea to the hydroxybenzoic ester preservative is 1:(1.5-1.8).
2. The skin whitening cream according to claim 1, wherein: The whitening and freckle-removing agent specifically comprises a combination of niacinamide, ferulic acid, and citric acid, and the mass ratio of the niacinamide, the ferulic acid, and the citric acid is (1-1.2):(0.6-0.9):(0.1-0.2). The whitening and freckle-removing cream further comprises 1.8-2wt% stabilizer, and the stabilizer specifically is hydroxypropyl cyclodextrin, and the whitening and freckle-removing agent needs to be pre-combined with the stabilizer before being added.
3. The skin whitening cream according to claim 2, wherein: The pre-combination process comprises the following steps: A1, niacinamide and ferulic acid are weighed according to the proportion, added into anhydrous ethanol at 45-50℃, and fully dissolved to obtain a mixed ethanol solution; citric acid and hydroxypropyl cyclodextrin are weighed according to the proportion, added into distilled water, and fully dissolved to obtain a mixed aqueous solution; A2, the mixed aqueous solution is heated to 45-50℃, and magnetic stirring is performed while the mixed ethanol solution is added dropwise; after the dropwise addition is completed, the temperature is kept constant and the stirring is continued for 30-40min to obtain a co-crystal solution, and then the co-crystal solution is heated to 55-60℃ and vacuum dried to obtain the pre-combined whitening and freckle-removing agent.
4. The skin whitening cream according to claim 2, wherein: The plant extract agent further comprises 0.05-0.1wt% sophora root extract and 0.1-0.2wt% α-arbutin.
5. A whitening and spot-fading cream according to any one of claims 1-4, characterized in that: The hydrophilic emulsifier is at least one of sodium polyacrylate, C13-14 isoparaffin, and laureth-7; and the oleophilic emulsifier is at least one of glyceryl stearate, polyethylene glycol glyceryl stearate, and cetearyl alcohol.
6. A whitening and spot-fading cream according to any one of claims 1-4, characterized in that: The hydroxybenzoic ester preservative is at least one of hydroxybenzoic acid methyl ester, hydroxybenzoic acid ethyl ester, and hydroxybenzoic acid propyl ester.
7. A whitening and spot-fading cream according to any one of claims 1-4, characterized in that: The humectant is at least one of glycerin, propylene glycol, sodium hyaluronate, panthenol.
8. A whitening and spot-fading cream according to any one of claims 1-4, characterized in that: The emollient is at least one of caprylic / capric triglyceride, cyclohexasiloxane, cyclononamethicone.
9. A method for preparing a skin-whitening and freckle-removing cream for preparing the skin-whitening and freckle-removing cream according to any one of claims 1 to 8, characterized by, The method comprises the following steps: S1, 90% solvent, allantoin, panthenol, spirulina extract and purslane extract are taken as A material, and are added into a water phase pot in sequence and heated to 80-85°C under stirring; the humectant and thickening agent are mixed fully in advance and taken as B material, and then are added into the water phase pot, and A material and B material are mixed fully and uniformly under continuous stirring, to obtain a water phase material; S2, the lipophilic emulsifier, homogenizing agent, antioxidant, hydroxybenzoic ester preservative are taken as C material, and are added into an oil phase pot in sequence and heated to 80-85°C under stirring, and the oil phase material is obtained after mixing uniformly; S3, the water phase material is pumped into a vacuum emulsification pot, and is homogenized for 1-2 min, the stirring speed is adjusted to 1000-1200 r / min, then the oil phase material is pumped in, and is homogenized for 4-5 min under vacuum; S4, cooling water is opened, and is cooled to 60-65°C, 8% solvent, whitening and freckle-removing agent, water phase emulsifier, emollient, and the remaining skin conditioner and plant extract are taken as D material, and are added in sequence, and are homogenized for 4-5 min; S5, the temperature is continuously lowered to 45-50°C, the remaining solvent, bis(hydroxymethyl)imidazolidinyl urea and fragrance are added, and are continuously homogenized for 1-2 min, the temperature is lowered to below 38°C, and the material is discharged, to obtain a whitening and freckle-removing cream.