Optical fiber ranging tool and POCT fluorescence immunoassay instrument thereof

Abstract

The optical fiber distance measuring tool comprises a main body which is provided with a central hole, a left hole located at the left side of the central hole, a right hole located at the right side of the central hole, a front hole located in front of the central hole, and a rear hole located behind the central hole; the central hole is communicated with a central observation port, the left hole is communicated with a left observation port, the right hole is communicated with a right observation port, the front hole is communicated with a front observation port, and the rear hole is communicated with a rear observation port; the plurality of optical fibers are respectively arranged in the central hole, the left hole, the right hole, the front hole and the rear hole, and the tail ends of the plurality of optical fibers are respectively exposed from the corresponding central observation port, the left observation port, the right observation port, the front observation port and the rear observation port; by combining optical fiber on-off feedback and recording critical coordinates of optical fibers triggered by light spots, the center position of the light spots and the center of the center hole are located on the same axis, detection light accurately covers a detection line area, meanwhile, the optical fiber on-off feedback can be visually seen through an observation opening, and calibration by technicians is facilitated.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and more particularly to a fiber optic ranging fixture and its POCT fluorescence immunoassay analyzer. Background Technology

[0002] POCT fluorescence immunoassay is a rapid detection and analysis technology that is close to the patient. It has significant advantages such as simplicity, efficiency, short testing cycle, and small sample volume. It can meet the needs of doctors and patients in terms of test report time. Moreover, it is relatively easy to operate and can be completed by clinicians, nurses, or even patients or their families.

[0003] In existing POCT fluorescence immunoassay analyzers, the accuracy of the detection light emitted by the optical module is difficult to guarantee. The detection light needs to precisely illuminate the detection line area of ​​the test strip to excite the fluorescent material on the detection line to generate a fluorescence signal. However, due to factors such as assembly errors, thermal expansion and contraction of components, and mechanical wear after long-term use, the position of the detection light is prone to deviation, resulting in inaccurate coverage of the detection line area, thus affecting the accuracy and reliability of the test results. For example, when the detection light deviates from the detection line, it may cause incomplete acquisition of the fluorescence signal or be affected by background interference, leading to deviations in the test results.

[0004] If the position of the detection light shifts, existing instruments often lack an effective adjustment mechanism. This typically requires complex adjustments and calibrations by specialized technicians, which not only consumes significant time and manpower but may also introduce new errors during the adjustment process. Furthermore, due to the complex internal structure of the instrument, adjusting the position of the detection light is difficult and demands a high level of expertise from the technicians.

[0005] Therefore, it is necessary to develop a fiber optic ranging fixture and its POCT fluorescence immunoassay analyzer to solve the above problems. Summary of the Invention

[0006] The purpose of this invention is to provide an easily calibrated fiber optic ranging fixture and its POCT fluorescence immunoassay analyzer.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a fiber optic ranging fixture, comprising: The main body has a central hole, a left hole located to the left of the central hole, a right hole located to the right of the central hole, a front hole located in front of the central hole, and a rear hole located behind the central hole; The central hole is connected to a central observation port, the left hole is connected to a left observation port, the right hole is connected to a right observation port, the front hole is connected to a front observation port, and the rear hole is connected to a rear observation port. Several optical fibers are respectively disposed in the central hole, the left hole, the right hole, the front hole and the rear hole, and the ends of the several optical fibers are exposed from the corresponding central observation port, the left observation port, the right observation port, the front observation port and the rear observation port.

[0008] Furthermore, the distances between the left hole, the right hole, the front hole, the rear hole, and the center hole are the same.

[0009] Furthermore, the diameters of the central hole, the left hole, the right hole, the front hole, and the rear hole are the same.

[0010] Furthermore, the main body has a central optical fiber fixing groove formed by a recess from the surface inward, the two ends of the central optical fiber fixing groove are respectively connected to the central hole and the central observation port, a central optical fiber is installed in the central optical fiber fixing groove, and the two ends of the central optical fiber extend into the central hole and the central observation port respectively.

[0011] Furthermore, the main body has a left optical fiber fixing groove formed by a recess from the surface inward. The two ends of the left optical fiber fixing groove are respectively connected to the left hole and the left observation port. A left optical fiber is installed in the left optical fiber fixing groove, and the two ends of the left optical fiber extend into the left hole and the left observation port respectively.

[0012] Furthermore, the main body has a right optical fiber fixing groove formed by a recess from the surface inward. The two ends of the right optical fiber fixing groove are respectively connected to the right hole and the right observation port. A right optical fiber is provided in the right optical fiber fixing groove, and the two ends of the right optical fiber extend into the right hole and the right observation port respectively.

[0013] Furthermore, the main body has a front fiber fixing groove formed by recessing from the surface inward. The two ends of the front fiber fixing groove are respectively connected to the front hole and the front observation port. A front fiber is provided in the front fiber fixing groove, and the two ends of the front fiber extend into the front hole and the front observation port respectively.

[0014] Furthermore, the main body has a rear optical fiber fixing groove formed by recessing from the surface inward. The two ends of the rear optical fiber fixing groove are respectively connected to the rear hole and the rear observation port. A rear optical fiber is provided in the rear optical fiber fixing groove, and the two ends of the rear optical fiber extend into the rear hole and the rear observation port respectively.

[0015] Furthermore, the positions of the central hole, the left hole, the right hole, the front hole, and the rear hole are the same as the positions of the test area of ​​the detection strip, and the center of the central hole coincides with the center of the test area of ​​the detection strip.

[0016] A POCT fluorescence immunoassay analyzer includes the aforementioned fiber optic ranging fixture, wherein the fiber optic ranging fixture is limited by a slot.

[0017] Compared with the prior art, the beneficial effects of the present invention are as follows: The fiber optic ranging fixture and its POCT fluorescence immunoassay analyzer of the present invention are easy to calibrate. High-precision positioning is achieved through multi-fiber collaborative calibration. The central hole and the four surrounding holes (left, right, front, and back) accurately correspond to the area to be measured. Combined with fiber optic on / off feedback, by recording the critical coordinates of each fiber triggered by the light spot, the center position of the light spot and the center of the central hole are on the same axis, so that the detection light accurately covers the detection line area. At the same time, the fiber optic on / off feedback can be directly seen through the observation port, which is convenient for technicians to calibrate. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort, wherein: Figure 1 This is an exploded view of an optical fiber ranging fixture according to the present invention; Figure 2 for Figure 1 A schematic diagram of the main partial structure of the fiber optic ranging fixture shown. Figure 3 for Figure 1 A schematic diagram of another part of the main structure of the fiber optic ranging fixture shown. Figure 4 This is a three-dimensional structural schematic diagram of a fiber optic ranging fixture and its POCT fluorescence immunoassay analyzer according to the present invention. Figure 5 Figure 4 The diagram shows another angle of the fiber optic ranging fixture and its POCT fluorescence immunoassay analyzer.

[0019] In the diagram: 100. Fiber optic ranging fixture; 1. Main body; 11. Mounting slot; 12. Cover plate; 13. Fiber optic fixing slot; 131. Central fiber optic fixing slot; 1311. Central observation port; 1312. Central hole; 132. Left fiber optic fixing slot; 1321. Left observation port; 1322. Left hole; 133. Right fiber optic fixing slot; 1331. Right observation port; 1332. Right hole; 134. Front fiber optic fixing slot; 1341. Front observation port; 1342. Front hole; 135. Rear fiber optic fixing slot; 1351. Rear observation port; 1352. Rear hole; 2. Fiber optic cable; 21. Central optical fiber; 22. Left optical fiber; 23. Right optical fiber; 24. Front optical fiber; 25. Rear optical fiber; 200. POCT fluorescence immunoassay analyzer; 10. Platform; 101. Slot; 20. Support; 201. Horizontal beam; 202. Vertical beam; 30. Transmission module; 301. X-axis transmission assembly; 3011. X-axis motor; 3012. Connecting block; 3013. Transmission shaft; 3014. Synchronous belt; 3015. Track; 3016. Slider; 302. Y-axis transmission assembly; 3021. Y-axis drive component; 3022. Base block; 40. Optical module. Detailed Implementation

[0020] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0021] Please refer to Figures 1 to 5 This invention relates to an optical fiber ranging fixture and its POCT fluorescence immunoassay analyzer.

[0022] Please refer to Figures 1 to 3 The fiber optic ranging fixture 100 includes a main body 1 and several optical fibers 2 installed inside the main body 1.

[0023] The main body 1 has a mounting groove 11 formed by recessing from the lower surface inward, and a cover plate 12 is provided at the mounting groove 11. The shape of the cover plate 12 matches the shape of the mounting groove 11.

[0024] The main body 1 also has multiple fiber optic fixing slots 13 recessed inward from the bottom of the mounting slot 11, and several optical fibers 2 are respectively installed in the fiber optic fixing slots 13. The cover plate 12 is fixedly connected to the main body 1 by bolts or screws to fix the position of the optical fibers 2.

[0025] The fiber optic fixing groove 13 includes a central fiber optic fixing groove 131, in which a central fiber optic cable 21 is installed. The central fiber optic fixing groove 131 is recessed inward from the bottom of the mounting groove 11. One end of the central fiber optic fixing groove 131 penetrates the end face of the main body 1 to form a central observation port 1311, and the other end penetrates the upper surface of the main body 1 to form a central hole 1312. One end of the central fiber optic cable 21 is placed in the central observation port 1311, and the other end extends along the central fiber optic fixing groove 131 and is placed in the central hole 1312.

[0026] The fiber optic fixing slot 13 includes a left fiber optic fixing slot 132, in which a left fiber optic cable 22 is installed. The left fiber optic fixing slot 132 is recessed inward from the bottom of the mounting slot 11. One end of the left fiber optic fixing slot 132 penetrates the end face of the main body 1 to form a left observation port 1321, and the other end penetrates the upper surface of the main body 1 to form a left hole 1322. One end of the left fiber optic cable 22 is placed in the left observation port 1321, and the other end extends along the left fiber optic fixing slot 132 and is placed in the left hole 1322. Specifically, the left hole 1322 is located to the left of the central hole 1312.

[0027] The fiber optic fixing slot 13 includes a right fiber optic fixing slot 133, in which a right fiber optic cable 23 is installed. The right fiber optic fixing slot 133 is recessed inward from the bottom of the mounting slot 11. One end of the right fiber optic fixing slot 133 penetrates the end face of the main body 1 to form a right observation port 1331, and the other end penetrates the upper surface of the main body 1 to form a right hole 1332. One end of the right fiber optic cable 23 is placed in the right observation port 1331, and the other end extends along the right fiber optic fixing slot 133 and is placed in the right hole 1332. Specifically, the right hole 1332 is located to the right of the central hole 1312.

[0028] The fiber optic fixing slot 13 includes a front fiber optic fixing slot 134, in which a front fiber optic cable 24 is installed. The front fiber optic fixing slot 134 is recessed inward from the bottom of the mounting slot 11. One end of the front fiber optic fixing slot 134 penetrates the end face of the main body 1 to form a front observation port 1341, and the other end penetrates the upper surface of the main body 1 to form a front hole 1342. One end of the front fiber optic cable 24 is placed in the front observation port 1341, and the other end extends along the front fiber optic fixing slot 134 and is placed in the front hole 1342. Specifically, the front hole 1342 is located in front of the central hole 1312.

[0029] The fiber optic fixing groove 13 includes a rear fiber optic fixing groove 135, in which a rear fiber optic cable 25 is installed. The rear fiber optic fixing groove 135 is recessed inward from the bottom of the mounting groove 11. One end of the rear fiber optic fixing groove 135 penetrates the end face of the main body 1 to form a rear observation port 1351, and the other end penetrates the upper surface of the main body 1 to form a rear hole 1352. One end of the rear fiber optic cable 25 is placed in the rear observation port 1351, and the other end extends along the rear fiber optic fixing groove 135 and is placed in the rear hole 1352. Specifically, the rear hole 1352 is located behind the central hole 1312.

[0030] Left hole 1322, right hole 1332, front hole 1342, and rear hole 1352 surround the central hole 1312. Specifically, the diameters of the left hole 1322, right hole 1332, front hole 1342, rear hole 1352, and central hole 1312 are all the same, 1 mm, and the center distance between the left hole 1322, right hole 1332, front hole 1342, rear hole 1352 and central hole 1312 is 3.5 mm.

[0031] The shape of the fiber optic ranging fixture 100 matches the shape of the test strip (not shown). The positions of its left hole 1322, right hole 1332, front hole 1342, rear hole 1352 and center hole 1312 are also the same as the position of the test area of ​​the test strip. Specifically, the center of the center hole 1312 coincides with the center of the test area of ​​the test strip.

[0032] Please refer to Figures 4 to 5 The POCT fluorescence immunoassay analyzer 200 includes a platform 10, a support 20 mounted on the platform 10, a transmission module 30 mounted on the support 20, and an optical module 40 driven by the transmission module 30.

[0033] The platform 10 is horizontal and is used to support the bracket 20. Its surface is covered with a slot 101, which is fixed to the surface of the platform 10 by bolts or screws.

[0034] The support 20 includes a horizontal beam 201 and a vertical beam 202. There is a pair of vertical beams 202. The bottom of the vertical beams 202 is fixedly connected to the platform 10, and the top extends vertically upward to connect to the horizontal beams 201. The two ends of the horizontal beams 201 are vertically fixedly connected to the pair of vertical beams 202.

[0035] The transmission module 30 includes an X-axis transmission assembly 301 and a Y-axis transmission assembly 302.

[0036] The X-axis transmission assembly 301 includes an X-axis motor 3011 mounted on a bracket 20 and a connecting block 3012 driven by the X-axis motor 3011. The X-axis motor 3011 is fixed to the outside of any bracket 20. A transmission shaft 3013 is mounted on the outside of another bracket 20. The conveying end of the X-axis motor 3011 and the transmission shaft 3013 are connected by a synchronous belt 3014, that is, the synchronous belt 3014 surrounds the transmission shaft 3013 and the conveying end of the X-axis motor 3011.

[0037] Furthermore, a track 3015 is laid on the lower surface of the crossbeam 201, and the track 3015 extends from one end of the crossbeam 201 to the other end. The connecting block 3012 is fixedly installed on the synchronous belt 3014. A slider 3016 is provided on the lower surface of the connecting block 3012. The slider 3016 is movably connected to the track 3015. The X-axis motor 3011 drives the connecting block 3012 to move along the track 3015 through the slider 3016.

[0038] The Y-axis transmission assembly 302 includes a Y-axis drive 3021 and a base block 3022 driven by the Y-axis drive 3021. The Y-axis drive 3021 is a lead screw motor, fixed to one end of the connecting block 3012. Meanwhile, a track 3015 is laid on the lower surface of the connecting block 3012, extending from one end of the connecting block 3012 to the other end. The Y-axis drive 3021 pushes the base block 3022 to move along the track 3015 laid on the lower surface of the connecting block 3012.

[0039] The optical module 40 is mounted on the base block 3022 and can produce a light spot with a diameter of 1.5mm.

[0040] When using the fiber optic ranging fixture and its POCT fluorescence immunoassay analyzer, the detection strip is removed from the slot 101, the fiber optic ranging fixture 100 is inserted into the slot 101, the optical module 40 is activated, generating a light spot with a diameter of 1.5 mm. The X-axis drive assembly 301 and the Y-axis drive assembly 302 drive the optical module 40 to move above the fiber optic ranging fixture 100, and the emitted light spot illuminates the surface of the fiber optic ranging fixture 100. By adjusting the X-axis drive assembly 301 and the Y-axis drive assembly 302... 02. The light spot emitted by the optical module 40 illuminates the central aperture 1312. The central optical fiber 21 guides the light, and the central optical fiber 21 at the central observation port 1311 lights up. When the central optical fiber 21 is observed to be lit, the position of the light spot is initially confirmed and recorded. Then, the light spot is moved unidirectionally until the central optical fiber 21 turns off, and the position is recorded. The light spot is moved until the left observation port 1321 lights up. At this time, the edge of the light spot illuminates the left aperture 1322, and the position is recorded. The light spot returns along the original path, and the left optical fiber 22 turns off, and the position is recorded. In this way, the left optical fiber 22, right optical fiber 23, front optical fiber 24, and rear optical fiber 25 are lit up in sequence (the lighting order can be changed according to needs), and the position is recorded one by one to obtain the coordinates of the above-mentioned optical fibers 2. The center of the light spot and the center of the central aperture 1312 are aligned on the same axis through a program or algorithm to complete the ranging and positioning.

[0041] This invention discloses a fiber optic ranging fixture and its POCT fluorescence immunoassay analyzer, which is easy to calibrate. It achieves high-precision positioning through multi-fiber collaborative calibration. The central hole and the four surrounding holes (left, right, front, and back) precisely correspond to the area to be measured. Combined with fiber optic on / off feedback, by recording the critical coordinates of each fiber triggered by the light spot, the center position of the light spot is aligned with the center of the central hole on the same axis, so that the detection light accurately covers the detection line area. At the same time, the fiber optic on / off feedback can be directly observed through the observation port, which is convenient for technicians to calibrate.

[0042] The above description is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. A fiber optic ranging fixture, characterized in that, include: The main body (1) has a central hole (1312), a left hole (1322) located to the left of the central hole (1312), a right hole (1332) located to the right of the central hole (1312), a front hole (1342) located in front of the central hole (1312), and a rear hole (1352) located behind the central hole (1312). The central hole (1312) is connected to the central observation port (1311), the left hole (1322) is connected to the left observation port (1321), the right hole (1332) is connected to the right observation port (1331), the front hole (1342) is connected to the front observation port (1341), and the rear hole (1352) is connected to the rear observation port (1351). Several optical fibers (2) are respectively disposed in the central hole (1312), the left hole (1322), the right hole (1332), the front hole (1342) and the rear hole (1352), and the ends of the several optical fibers (2) are exposed from the corresponding central observation port (1311), the left observation port (1321), the right observation port (1331), the front observation port (1341) and the rear observation port (1351).

2. The fiber optic ranging fixture according to claim 1, characterized in that, The distances between the left hole (1322), the right hole (1332), the front hole (1342), and the rear hole (1352) and the center hole (1312) are the same.

3. The fiber optic ranging fixture according to claim 1 or 2, characterized in that, The diameters of the central hole (1312), the left hole (1322), the right hole (1332), the front hole (1342), and the rear hole (1352) are the same.

4. The fiber optic ranging fixture according to claim 1, characterized in that, The main body (1) has a central optical fiber fixing groove (131) formed by recessing from the surface inward. The two ends of the central optical fiber fixing groove (131) are respectively connected to the central hole (1312) and the central observation port (1311). A central optical fiber (21) is installed in the central optical fiber fixing groove (131). The two ends of the central optical fiber (21) extend into the central hole (1312) and the central observation port (1311) respectively.

5. The fiber optic ranging fixture according to claim 1, characterized in that, The main body (1) has a left optical fiber fixing groove (132) formed by recessing from the surface inward. The two ends of the left optical fiber fixing groove (132) are respectively connected to the left hole (1322) and the left observation port (1321). A left optical fiber (22) is installed in the left optical fiber fixing groove (132). The two ends of the left optical fiber (22) extend into the left hole (1322) and the left observation port (1321) respectively.

6. The fiber optic ranging fixture according to claim 1, characterized in that, The main body (1) has a right optical fiber fixing groove (133) formed by recessing from the surface inward. The two ends of the right optical fiber fixing groove (133) are respectively connected to the right hole (1332) and the right observation port (1331). A right optical fiber (23) is provided in the right optical fiber fixing groove (133). The two ends of the right optical fiber (23) extend into the right hole (1332) and the right observation port (1331) respectively.

7. The fiber optic ranging fixture according to claim 1, characterized in that, The main body (1) has a front fiber fixing groove (134) formed by recessing from the surface inward. The two ends of the front fiber fixing groove (134) are respectively connected to the front hole (1342) and the front observation port (1341). A front fiber (24) is provided in the front fiber fixing groove (134), and the two ends of the front fiber (24) extend into the front hole (1342) and the front observation port (1341) respectively.

8. The fiber optic ranging fixture according to claim 1, characterized in that, The main body (1) has a rear optical fiber fixing groove (135) formed by recessing from the surface inward. The two ends of the rear optical fiber fixing groove (135) are respectively connected to the rear hole (1352) and the rear observation port (1351). The rear optical fiber fixing groove (135) is provided with a rear optical fiber (25). The two ends of the rear optical fiber (25) extend into the rear hole (1352) and the rear observation port (1351) respectively.

9. The fiber optic ranging fixture according to claim 1, characterized in that, The positions of the central hole (1312), the left hole (1322), the right hole (1332), the front hole (1342), and the rear hole (1352) are the same as the positions of the test area of ​​the test strip, and the center of the central hole (1312) coincides with the center of the test area of ​​the test strip.

10. A POCT fluorescence immunoassay analyzer, characterized in that, include: The fiber optic ranging fixture according to any one of claims 1 to 9, wherein the fiber optic ranging fixture is limited by a slot (101).

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