Separation column and strontium [90Sr]-yttrium [90Y] generator

Abstract

The invention provides a separation column and a strontium [90Sr]-yttrium [90Y] generator, the separation column comprises: a sleeve, the two ends of the sleeve in the axial direction are respectively a first closed end and a second closed end, and the peripheral side of the sleeve is provided with a liquid inlet and a liquid outlet; the filter plate is arranged in the sleeve, the interior of the sleeve is divided into a first inner cavity and a second inner cavity by the filter plate, the first inner cavity and the second inner cavity are arranged in the axial direction of the sleeve, the liquid inlet is communicated with the first inner cavity, the first inner cavity is used for containing an adsorbent, and the adsorbent is used for adsorbing strontium [90Sr] or yttrium [90Y]; the overflow pipe is arranged in the sleeve and penetrates through the filter plate, one end of the overflow pipe is located in the second inner cavity, the other end of the overflow pipe is connected to the sleeve, and the overflow pipe is communicated between the second inner cavity and the liquid outlet; the liquid inlet and the liquid outlet are arranged close to the first closed end in the axial direction of the sleeve.

Description

Technical Field

[0001] This disclosure relates to the field of radionuclide generation technology, and more particularly to a separation column and strontium [ 90 Sr]-Yttrium[ 90 Y] generator. Background Technology

[0002] In related technologies, yttrium is produced using a nuclide generator. 90 When obtaining Y], it is often difficult to obtain yttrium that meets medical standards through a single separation method. 90 Y] solution, therefore, multiple separation columns are usually connected in series to separate yttrium [ 90 Y] is subjected to multiple separation and extraction processes.

[0003] However, due to the limitations of the separation column structure in related technologies, the assembly operation is relatively inconvenient when multiple separation columns are connected in series. Furthermore, the multiple separation columns connected in series tend to have a large spatial distribution range, which is not conducive to reducing the overall size of the generator, resulting in poor portability and ease of use of the generator. Summary of the Invention

[0004] This disclosure aims to address at least one of the technical problems existing in the prior art or related technologies.

[0005] In view of this, a separation column is provided according to a first aspect of the present disclosure, comprising:

[0006] The sleeve has a first closed end and a second closed end at its two axial ends, and an inlet and an outlet are provided on the circumference of the sleeve.

[0007] A filter plate, disposed inside the sleeve, divides the interior of the sleeve into a first inner cavity and a second inner cavity. The first and second inner cavities are arranged along the axial direction of the sleeve. The liquid inlet is connected to the first inner cavity, which is used to contain the adsorbent, which is used to adsorb strontium. 90 Sr] or yttrium 90 Y];

[0008] An overflow pipe is installed inside the sleeve, passes through the filter plate, and one end of the overflow pipe is located in the second inner cavity, while the other end is connected to the sleeve. The overflow pipe connects the second inner cavity and the outlet.

[0009] Along the axial direction of the casing, both the inlet and outlet are located close to the first closed end.

[0010] In one feasible implementation, the separation column further includes:

[0011] The liquid inlet connector has a liquid inlet hole. The liquid inlet connector is located outside the sleeve and is arranged corresponding to the liquid inlet. The liquid inlet hole is connected to the liquid inlet.

[0012] The liquid outlet connector is provided with a liquid outlet hole. The liquid outlet connector is located outside the sleeve and is arranged corresponding to the liquid outlet. The liquid outlet hole is connected to the liquid outlet.

[0013] The axial direction of both the inlet and outlet connectors intersects with the axial direction of the sleeve.

[0014] In one feasible implementation, along the axial direction of the sleeve, both the inlet and outlet connectors are located between the first and second closed ends; and / or

[0015] The axial distance between the inlet end and the first closed end of the inlet connector on the sleeve is less than or equal to the axial distance between the inlet and the first closed end on the sleeve; and / or

[0016] The distance between the outlet end and the first closed end of the liquid outlet connector in the axial direction of the sleeve is less than or equal to the distance between the outlet and the first closed end in the axial direction of the sleeve.

[0017] In one feasible implementation, the length of the first inner cavity in the axial direction of the sleeve is greater than or equal to the length of the second inner cavity in the axial direction of the sleeve.

[0018] According to a second aspect of the embodiments of this disclosure, a strontium [ 90 Sr]-Yttrium[ 90 Y] generator, including:

[0019] The housing assembly provides installation space.

[0020] The first container is located within the installation space;

[0021] The second container is located within the installation space and is used to hold the rinsing solution.

[0022] A power unit is installed within the installation space, and the liquid input end of the power unit is connected to a second container;

[0023] A shielding assembly is disposed within the installation space, and the shielding assembly forms a receiving cavity;

[0024] Multiple separation columns as described in any of the first aspects above are disposed within the receiving cavity, and the multiple separation columns are connected in series between the liquid output end of the power assembly and the first container.

[0025] The power unit is used to drive the eluent solution in the second container to flow toward the separation column.

[0026] In one feasible implementation, the housing assembly includes:

[0027] The cylindrical section has an installation space, and the top of the cylindrical section has a cylinder opening, while the side wall of the cylindrical section has an operation opening.

[0028] The cover is detachably mounted on the cylinder body and is used to open or cover the cylinder opening.

[0029] The door section is hinged to the cylinder section and is used to open or cover the operating opening.

[0030] The first bracket is set in the installation space. The first bracket is arranged between the operating port and the cylinder opening along the height direction of the cylinder body. The power unit is set on the first bracket.

[0031] The second bracket is installed within the installation space, and the shielding component is installed on the second bracket;

[0032] Both the first container and the second container are arranged corresponding to the operation ports.

[0033] In one feasible implementation, the housing assembly further includes:

[0034] The telescopic frame has a fixed end and a free end at both ends in the telescopic direction. The fixed end is fixedly installed in the cylindrical part, and the free end is suitable for extending or retracting into the installation space through the operating port.

[0035] The third support is located at the free end, and the first container is detachably mounted on the third support;

[0036] The fourth support is located at the free end, and the second container is detachably mounted on the fourth support.

[0037] In one feasible implementation, the shielding component includes:

[0038] The tank body is located within the installation space;

[0039] The tank cover is detachably mounted on the tank body. The tank cover has an inlet for the inlet and an outlet for the outlet. When the tank cover is mounted on the tank body, the tank body and the tank cover form a receiving cavity. The inlet for the inlet and the outlet for the outlet are both connected to the receiving cavity.

[0040] Both the tank body and the tank cover are made of radioactive shielding material.

[0041] In one feasible implementation, the shielding component further includes:

[0042] The first shielding layer consists of multiple separation columns arranged at intervals along a predetermined direction within the receiving cavity. The first shielding layer is disposed between two adjacent separation columns and is made of radioactive shielding material.

[0043] A buffer pad is provided on the inner bottom wall of the tank body, and the second closed end is provided on the buffer pad;

[0044] The preset direction is perpendicular to the axial direction of the sleeve.

[0045] In one feasible embodiment, the cylindrical body is constructed as a multi-layer structure in the direction of the cylindrical wall thickness. The multi-layer structure includes a first wall layer, a second wall layer and a third wall layer arranged sequentially from the inside to the outside, and the installation space is enclosed by the first wall layer.

[0046] The first wall layer is made of a flexible material, while the second and third wall layers are made of different radioactive shielding materials, and the atomic number of the material in the second wall layer is less than that in the third wall layer.

[0047] The above description is merely an overview of the technical solution provided in this disclosure. In order to better understand the technical means of this disclosure and to implement it in accordance with the contents of the specification, and to make the above and other features and effects of this disclosure more obvious and understandable, the following are specific examples of the implementation methods of this disclosure. Attached Figure Description

[0048] Various other advantages and benefits will become apparent to those skilled in the art upon reading the following detailed description of exemplary embodiments. The accompanying drawings are for illustrative purposes only and are not intended to limit the scope of this disclosure. Furthermore, the same reference numerals denote the same parts throughout the drawings. In the drawings:

[0049] Figure 1 This is a schematic structural diagram of a separation column according to an embodiment of the present disclosure;

[0050] Figure 2 for Figure 1 A schematic cross-sectional view of the separation column is shown in the figure;

[0051] Figure 3 A schematic structural diagram of a separation column according to another embodiment of this disclosure;

[0052] Figure 4 for Figure 3 A schematic cross-sectional view of the separation column is shown in the figure;

[0053] Figure 5 Strontium [a] provided in one embodiment of this disclosure 90 Sr]-Yttrium[ 90 A schematic structural diagram of the Y] generator from the first perspective;

[0054] Figure 6 Strontium [a] provided in one embodiment of this disclosure 90 Sr]-Yttrium[ 90 A schematic structural diagram of the Y] generator from a second perspective;

[0055] Figure 7 for Figure 6 Strontium shown in the image [ 90 Sr]-Yttrium[90 A schematic cross-sectional view of the generator along the AA direction;

[0056] Figure 8 Strontium [a] provided in one embodiment of this disclosure 90 Sr]-Yttrium[ 90 A schematic structural diagram of the Y] generator from the third perspective;

[0057] Figure 9 Strontium [a] provided in one embodiment of this disclosure 90 Sr]-Yttrium[ 90 A schematic structural diagram of the Y] generator from the fourth perspective;

[0058] Figure 10 Strontium [a] provided in one embodiment of this disclosure 90 Sr]-Yttrium[ 90 A schematic structural diagram of the Y] generator from the fifth perspective;

[0059] Figure 11 A schematic structural diagram of a shielding component according to an embodiment of the present disclosure from a first-view perspective;

[0060] Figure 12 A schematic structural diagram of a shielding component according to an embodiment of this disclosure from a second perspective;

[0061] Figure 13 A schematic cross-sectional view of a shielding assembly according to an embodiment of this disclosure;

[0062] Figure 14 A schematic structural diagram of a first container according to an embodiment of this disclosure;

[0063] Figure 15 A schematic cross-sectional view of a first container provided in one embodiment of this disclosure.

[0064] in, Figures 1 to 15 The correspondence between the reference numerals and component names in the attached drawings is as follows:

[0065] 100. Separation column; 110. Sleeve; 120. Filter plate; 130. Overflow pipe; 140. Inlet connector; 150. Outlet connector;

[0066] 200. Shell assembly; 210. Cylindrical part; 220. Cover part; 230. Door part; 240. First bracket; 250. Second bracket; 260a. Telescopic frame; 260b. Third bracket; 260c. Fourth bracket; 270. Handle; 280. First buckle connector; 290. Double-ended pin;

[0067] 300, First container; 310, First tank body; 320, First tank lid; 330, Second tank body; 340, Second tank lid; 350, Silicone gasket;

[0068] 500. Power assembly; 510. Peristaltic pump; 520. Power battery;

[0069] 600, Shielding assembly; 610, Slot body; 620, Slot cover; 630, Second shielding layer; 640, Buffer pad; 650, Self-sealing quick connector; 660, Flip handle; 670, Second latch connector;

[0070] 1101, First closed end; 1102, Second closed end; 1103, Liquid inlet; 1104, Liquid outlet; 1105, First inner cavity; 1106, Second inner cavity;

[0071] 1401, Liquid Inlet;

[0072] 1501, Liquid outlet;

[0073] 2101. Installation space; 2102. Cylinder opening; 2103. Operating port;

[0074] 6001, Receiving cavity;

[0075] 6101. Protruding structure;

[0076] 6201, Input tube through port; 6202, Output tube through port; 6203, Groove structure. Detailed Implementation

[0077] Exemplary embodiments of the present disclosure will now be described in more detail with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.

[0078] In related technologies, yttrium is produced using a nuclide generator. 90 When obtaining Y], it is often difficult to obtain yttrium that meets medical standards through a single separation method. 90 Y] solution, therefore, multiple separation columns are usually connected in series to separate yttrium [ 90 Y] Perform multiple separation and extraction. The aforementioned separation column is usually cylindrical, with the two ends of the separation column constructed as the inlet and outlet, respectively. In practical applications, the separation column is arranged vertically with the inlet located above the outlet.

[0079] However, due to the aforementioned structure of the separation column, when multiple separation columns are connected in series, if they are arranged axially sequentially, the overall length of the series-connected separation columns will increase, making it more difficult for the generator to shield the separation columns from radiation and increasing the size of the shielding structure. This is not conducive to reducing the overall volume of the generator, resulting in poor portability and ease of use. If the multiple separation columns are arranged radially, although it is beneficial to reduce the spatial distribution range of the series-connected separation columns, a large height difference will be formed between the liquid inlet end of one of the two adjacent separation columns in the series path and the liquid outlet end of the other. Therefore, when assembling multiple separation columns placed vertically in the shielding container in series, the installation operation of the inter-column connecting pipe is inconvenient. In order to connect the aforementioned inter-column connecting pipe between two adjacent separation columns, the inter-column connecting pipe needs to be bent multiple times, which also increases the risk of bending and blockage of the inter-column connecting pipe.

[0080] In view of this, such as Figures 1 to 4 As shown, a separation column 100 is provided according to a first aspect of the present disclosure, comprising: a sleeve 110, the two ends of the sleeve 110 along its axial direction being a first closed end 1101 and a second closed end 1102, and an inlet 1103 and an outlet 1104 provided on the circumferential side of the sleeve 110; a filter plate 120 disposed inside the sleeve 110, the filter plate 120 dividing the interior of the sleeve 110 into a first inner cavity 1105 and a second inner cavity 1106, the first inner cavity 1105 and the second inner cavity 1106 being arranged along the axial direction of the sleeve 110, the inlet 1103 being connected to the first inner cavity 1105, the first inner cavity 1105 being used to contain an adsorbent, the adsorbent being used to adsorb strontium [ 90 Sr] or yttrium 90 Y]; Overflow pipe 130 is disposed inside sleeve 110. Overflow pipe 130 passes through filter plate 120, and one end of overflow pipe 130 is located in second inner cavity 1106, and the other end is connected to sleeve 110. Overflow pipe 130 connects the second inner cavity 1106 and outlet 1104; wherein, along the axial direction of sleeve 110, inlet 1103 and outlet 1104 are both arranged close to first closed end 1101.

[0081] The separation column 100 provided in this embodiment includes the aforementioned sleeve 110, filter plate 120 and overflow pipe 130. The sleeve 110 has an internal central hole structure. An inlet 1103 and an outlet 1104 are provided on the circumference of the sleeve 110. In practical applications, the inlet 1103 can be used to receive liquid media, and the outlet 1104 can be used to discharge the liquid media from the sleeve 110. The two axial ends of the sleeve 110 are a first closed end 1101 and a second closed end 1102, respectively, meaning both axial ends of the sleeve 110 are closed, thus preventing leakage of liquid media through the axial ends of the sleeve 110 and enhancing the flow guidance effect of the sleeve 110 on the liquid media. The overflow pipe 130 and the filter plate 120 are both disposed inside the sleeve 110. The two ends of the overflow pipe 130 are arranged close to the first closed end 1101 and the second closed end 1102, respectively. The end of the overflow pipe 130 closest to the first closed end 1101 is connected to the sleeve 110. Furthermore, the internal channel of the overflow pipe 130 is connected to the aforementioned outlet 1104. The filter plate 120 is sleeved on the overflow pipe 130, dividing the inside of the sleeve 110 into a first inner cavity 1105 and a second inner cavity 1106. The end of the overflow pipe 130 near the second closed end 1102 is located in the second inner cavity 1106. The aforementioned inlet 1103 is connected to the first inner cavity 1105. Based on this, the overflow pipe 130 can be connected between the aforementioned second inner cavity 1106 and the aforementioned outlet 1104. Correspondingly, when the aforementioned inlet 1103 is connected to a liquid medium, the liquid medium can flow sequentially through the first inner cavity 1105, the filter plate 120, the second inner cavity 1106, and the overflow pipe 130 as it flows towards the aforementioned outlet 1104, and then exits the separation column 100 through the outlet 1104. In practical applications, the aforementioned first inner cavity 1105 is used to contain materials suitable for adsorbing strontium. 90 Sr] or yttrium 90 The adsorbent [Y] is used so that when the liquid medium is introduced into the inlet 1103, the liquid medium flowing into the sleeve 110 easily interacts preferentially with the adsorbent, thereby facilitating the processing of strontium [Y]. 90[Y] Solution acquisition; both the inlet 1103 and the outlet 1104 are arranged along the axial direction of the sleeve 110 close to the aforementioned first closed end 1101, and the first inner cavity 1105 and the second inner cavity 1106 are arranged along the axial direction of the sleeve 110. Thus, when the separation column 100 is placed vertically, the aforementioned first closed end 1101 can serve as the top end of the separation column 100, and the aforementioned second closed end 1102 can serve as the bottom end of the separation column 100. Furthermore, given a fixed axial length of the sleeve 110, the inlet of the sleeve 110... The height difference between outlet 1103 and outlet 1104 can be reduced, which facilitates the radial arrangement of multiple separation columns 100 during series assembly. Connecting pipes between adjacent separation columns 100 along the series path reduces the degree and number of bends in the connecting pipes, lowering the risk of blockage. This improves the convenience of series assembly of multiple separation columns 100 while reducing the spatial distribution range of the connected columns, thus providing better conditions for strontium […]. 90 Sr]-Yttrium[ 90 The miniaturization and portability of the Y] generator provide favorable conditions.

[0082] It is understood that the series assembly of the aforementioned multiple separation columns 100 refers to the sequential connection of the multiple separation columns 100 in the flow path, that is, the multiple separation columns 100 are arranged in sequence according to a certain path. Among two adjacent separation columns 100 on the path, the outlet 1104 of one is connected to the inlet 1103 of the other. The inlet 1103 of the separation column 100 located at the upstream end of the path can be used to receive liquid media output by external equipment, and the outlet 1104 of the separation column 100 located at the downstream end of the path can be used to deliver liquid media to external equipment. Correspondingly, the liquid media received by the separation column 100 located at the upstream end of the path can flow through the multiple separation columns 100 in sequence along the aforementioned path.

[0083] Taking the number of separation columns 100 as an example, such as Figure 13As shown, both separation columns 100 can be disposed inside the shielding assembly 600, which is used to provide radioactive shielding for the separation columns 100. The axes of the two separation columns 100 can be parallel to each other, and the two separation columns 100 can be arranged radially at intervals along the sleeve 110 to reduce the spatial distribution range of the multiple separation columns 100 when arranged. The outlet 1104 of one of the two separation columns 100 can be connected to the inlet 1103 of the other through a connecting pipe (not shown in the figure) to form a series relationship between the two. In practical applications, the second closed ends 1102 of the two separation columns 100 can be arranged approximately flush so that when the two separation columns 100 are placed vertically, their heights are similar, thereby reducing the height difference between the inlet 1103 and outlet 1104 of the two separation columns 100, facilitating the assembly and connection of the aforementioned connecting pipe, and reducing the number of bends in the aforementioned connecting pipe.

[0084] It is understood that the aforementioned liquid medium may be, but is not limited to, an activation solution for activating the aforementioned adsorbent, a loading solution for loading the separation column 100 onto the column, and a solution for eluting or eluting yttrium. 90 One of the rinsing solutions of Y].

[0085] It should be noted that, in practical applications, the aforementioned separation column 100 can be used as a strontium [ 90 Sr]-Yttrium[ 90 A component of the Y] generator is used. Exemplarily, the aforementioned first cavity 1105 may be filled with the aforementioned adsorbent, which may be, but is not limited to, an adsorbent capable of selectively adsorbing strontium [ 90 Sr] or yttrium 90 Ion exchange resin adsorbents or macroporous adsorption resin adsorbents, etc., can be used in practical applications. In these applications, the adsorbents can be wet-filled into the first inner cavity 1105, and the filling quantity can be set according to actual needs. After filling the first inner cavity 1105 of the multiple separation columns 100 with adsorbent, the multiple separation columns 100 can be connected in series using connecting pipes. Then, an activation solution is injected into the separation column 100 located upstream of the series path, so that the activation solution flows sequentially through the multiple separation columns 100 in the series path, thereby activating the adsorbents within the multiple separation columns 100. After activating the multiple separation columns 100, an upper column solution can be injected into the separation column 100 located upstream of the series path, so that the upper column solution flows sequentially through the multiple separation columns 100 in the series path. The aforementioned upper column solution can contain yttrium […]. 90 Strontium of Y] 90 Sr] solution, for example, but not limited to strontium[ 90 Sr]-Yttrium[ 90In the equilibrium solution, as the solution flows through each separation column 100, the adsorbent within each separation column 100 can target the strontium in the solution. 90 Sr] or yttrium 90 Y] is adsorbed to allow strontium[ 90 Sr] and yttrium 90 [Y] separation, the column loading process can be carried out in a radioactive shielded container; after the column loading is completed and strontium [Y] is reached at 100 on each separation column. 90 Sr]-Yttrium[ 90 Before the decay equilibrium of yttrium [Y], a rinsing solution can be injected into the separation column 100 located at the upstream end of the series path to rinse the liquid medium in each separation column 100, reduce interfering components in the liquid medium in each separation column 100, and help ensure the subsequent acquisition of yttrium [Y]. 90 The purity of the Y] solution; after the aforementioned rinsing process is completed, multiple separation columns 100 can be loaded with strontium [ 90 Sr]-Yttrium[ 90 The shielding assembly 600 of the Y] generator is used to reduce strontium [ 90 Sr]-Yttrium[ 90 The radiation effect of the Y] generator on the surrounding environment can then be mitigated, and the aforementioned shielding component 600 can be transferred to the strontium [ 90 Sr]-Yttrium[ 90 The assembly line for the Y] generator, and with strontium[ 90 Sr]-Yttrium[ 90 Assemble and connect the other components of the Y] generator to complete the strontium [ 90 Sr]-Yttrium[ 90 Assembly of the Y] generator. Using the aforementioned strontium [ 90 Sr]-Yttrium[ 90 Y] generator acquires yttrium[ 90 When the Y] solution is in use, an eluent solution can be injected into the separation column 100 located at the upstream end of the series path, so that the aforementioned eluent solution removes the yttrium [Y] in each separation column 100. 90 Y] is carried out, and correspondingly, the liquid discharged from the separation column 100 located at the downstream end of the series path can be collected to realize the separation of yttrium[ 90 The acquisition of the Y] solution. Furthermore, based on the method of setting up multiple separation columns 100 in series, it is also possible to perform strontium […] in practical applications. 90 Sr] and yttrium 90 Multiple separations of Y] reduce strontium[ 90 The risk of Sr] leakage increases the amount of yttrium obtained. 90 The purity and quality of the Y solution.

[0086] It is understood that the aforementioned adsorbent can be phosphate ester resin particles, amide-ether resin particles, crown ether resin particles, etc. In practical applications, the aforementioned filter plate 120 is suitable for intercepting the aforementioned adsorbent in the first inner cavity 1105 and is suitable for the flow of liquid media. Accordingly, the filtration accuracy of the aforementioned filter plate 120 can be set in combination with the particle size of the aforementioned adsorbent. The aforementioned filter plate 120 can be, but is not limited to, a sand core sieve plate with specifications of G1-G5.

[0087] It is understood that the aforementioned sleeve 110, overflow tube 130, and connecting tube can be made of acid-resistant and radiation-resistant materials, which is beneficial to extending the service life of the aforementioned connecting tube and the aforementioned separation column 100. For example, the aforementioned connecting tube can be made of PEEK (Polyetheretherketone) or silicone; the aforementioned sleeve 110 and overflow tube 130 can be made of quartz glass, and the aforementioned sleeve 110 and overflow tube 130 can be an integral structure.

[0088] It is understood that the aforementioned arrangement of the inlet 1103 and outlet 1104 close to the first closed end 1101 along the axial direction of the sleeve 110 means that the axial distance between the inlet 1103 and the first closed end 1101 is less than the axial distance between the inlet 1103 and the second closed end 1102, and the axial distance between the outlet 1104 and the first closed end 1101 is less than the axial distance between the outlet 1104 and the second closed end 1102. In practical applications, the inlet 1103 and outlet 1104 can be arranged as close as possible to the first closed end 1101 or opened on the aforementioned first closed end 1101, based on the actual structure of the sleeve 110. This helps to extend the flow path of the liquid medium in the separation column 100, increase the arrangement height of the adsorbent in the sleeve 110, and improve the separation column 100's ability to absorb strontium […]. 90 Sr] and yttrium 90 The separation effect of Y].

[0089] It is understandable that, given a fixed structural dimension of the sleeve 110, and considering the amount of adsorbent filling the first inner cavity 1105, the aforementioned filter plate 120 can be arranged close to the second closed end 1102 to increase the volume of the first inner cavity 1105.

[0090] It is understood that the aforementioned overflow pipe 130 may include a connecting pipe section and a cantilever pipe section, wherein the cantilever pipe section is coaxially arranged with the sleeve 110, the two ends of the connecting pipe section are respectively connected to the cantilever pipe section and the sleeve 110, and the connecting pipe section is connected between the outlet 1104 and the cantilever pipe section.

[0091] It is understandable that the types, concentrations, and amounts of the aforementioned activation solution, column loading solution, and elution solution, as well as the types, particle sizes, and amounts of the aforementioned adsorbents, can all be set according to actual needs.

[0092] It is understandable that the type and adsorption capacity of the adsorbents packed in the multiple separation columns 100 in the series path can be different. For example, the multiple separation columns 100 can be uniformly packed with adsorbents capable of selectively adsorbing strontium. 90 The adsorbent for Sr is either filled with a selective adsorbent for yttrium [Sr], or the adsorbent is filled with a material capable of selectively adsorbing yttrium. 90 The adsorbent for [Y], or a portion of the separation column 100, is filled with an adsorbent capable of selectively adsorbing strontium [Y]. 90 The adsorbent is Sr, and another part of the separation column 100 is filled with yttrium […]. 90 The adsorbent is Y; preferably, the separation column 100 located downstream of the series path can be filled with an adsorbent capable of selectively adsorbing strontium [Y]. 90 Sr] adsorbent, to avoid Sr[ 90 Sr] leakage. Accordingly, the type of the aforementioned elution solution can be selected based on the actual situation of the aforementioned adsorbent.

[0093] For example, at least one separation column 100 in the series path may be filled with an adsorbent for adsorbing interfering components, thereby facilitating the purification of the liquid medium flowing through the separation column 100, for obtaining yttrium [ 90 The purity and quality of the Y] solution are guaranteed; the aforementioned interfering components may be, but are not limited to, non-strontium [ 90 Sr] and yttrium 90 Inorganic ions and organic fragments of Y].

[0094] Taking the aforementioned series-connected separation columns 100 as an example, and with an effective volume of 100 greater than or equal to 5 mL and less than or equal to 12 mL, two optional combinations of the aforementioned solutions and adsorbents are provided below:

[0095] (1) The upstream separation column 100 is filled with 4.0 g of phosphate ester resin particles as adsorbent; the downstream separation column 100 is filled with 1.0 g of amide-ether resin particles as adsorbent; the activation solution is 10 mL of 0.1 mol / L nitric acid solution; the column loading solution is a 10 mL solution of 0.1 mol / L nitric acid with an activity of 50 mCi, containing 10 mL of strontium nitrate (Strontium-90); after the column loading is completed and the Strontium [ 90 Sr]-Yttrium[ 90 The elution solution used during the elution process before the decay equilibrium of yttrium [Y] was 20 mL of 3.0 mol / L nitric acid solution; in obtaining yttrium [ 90The rinsing solution used in the Y] solution process is nitric acid solution, and the amount and concentration can be set according to actual needs.

[0096] (2) Both separation columns 100 can be filled with 5.0 g of crown ether resin particles as adsorbent; the activation solution is 10 mL of 0.1 mol / L nitric acid solution; the loading solution is a 10 mL solution of strontium nitrate (strontium-90) with an activity of 50 mCi, and a system of 4.0 mol / L nitric acid; after loading is completed and strontium […] is reached in each separation column 100… 90 Sr]-Yttrium[ 90 The elution solution used during the elution process before the decay equilibrium of yttrium [Y] was 20 mL of 4.0 mol / L nitric acid solution; in obtaining yttrium [ 90 The rinsing solution used in the Y] solution process is nitric acid solution, and the amount and concentration can be set according to actual needs.

[0097] It is understandable that the separation column 100 is used in the aforementioned strontium [ 90 Sr]-Yttrium[ 90 In the case of the Y] generator, when strontium[ 90 Sr]-Yttrium[ 90 After the Y] generator is assembled, it can be left for about 5 days to allow the strontium [ 90 Sr]-Yttrium[ 90 Y] is used after decay equilibrium.

[0098] like Figures 1 to 4 As shown, in some examples, the separation column 100 further includes: a liquid inlet connector 140 with a liquid inlet hole 1401, the liquid inlet connector 140 being disposed outside the sleeve 110 and corresponding to the liquid inlet 1103, the liquid inlet hole 1401 being connected to the liquid inlet 1103; and a liquid outlet connector 150 with a liquid outlet hole 1501, the liquid outlet connector 150 being disposed outside the sleeve 110 and corresponding to the liquid outlet 1104, the liquid outlet hole 1501 being connected to the liquid outlet 1104; wherein, the axial direction of both the liquid inlet connector 140 and the liquid outlet connector 150 intersects the axial direction of the sleeve 110.

[0099] In this technical solution, the separation column 100 may further include the aforementioned inlet connector 140 and the aforementioned outlet connector 150. Based on the aforementioned configuration, the separation column 100 can respectively receive and discharge liquid media through the aforementioned inlet connector 140 and the aforementioned outlet connector 150, facilitating connection with external pipelines; by setting the axial direction of the aforementioned inlet connector 140 and the axial direction of the aforementioned outlet connector 150 to intersect with the axial direction of the sleeve 110, the aforementioned inlet connector 140 and the outlet connector 150 can be arranged at an angle relative to the sleeve 110. Therefore, given a fixed length of the aforementioned inlet hole 1401 and the aforementioned outlet hole 1501, the distribution length of the inlet connector 140 and the outlet connector 150 in the axial and radial directions of the sleeve 110 can be reduced, which is beneficial to further improve the structural compactness of the separation column 100. Furthermore, when multiple separation columns 100 are arranged radially, it is beneficial to reduce the radial distance between adjacent separation columns 100, thus providing a better foundation for Strontium […]. 90 Sr]-Yttrium[ 90 The miniaturization and portability of the Y generator provide more favorable conditions.

[0100] For example, the aforementioned inlet connector 140, outlet connector 150, sleeve 110 and overflow pipe 130 are an integral structure and are all made of quartz glass.

[0101] like Figures 1 to 4 As shown, in some examples, along the axial direction of the sleeve 110, both the inlet connector 140 and the outlet connector 150 are located between the first closed end 1101 and the second closed end 1102; and / or

[0102] The axial distance between the inlet end of the inlet connector 140 and the first closed end 1101 in the sleeve 110 is less than or equal to the axial distance between the inlet port 1103 and the first closed end 1101 in the sleeve 110; and / or

[0103] The distance between the outlet end of the outlet connector 150 and the first closed end 1101 in the axial direction of the sleeve 110 is less than or equal to the distance between the outlet 1104 and the first closed end 1101 in the axial direction of the sleeve 110.

[0104] In this technical solution, the inlet connector 140 and the outlet connector 150 can be positioned along the axial direction of the sleeve 110, both located between the first closed end 1101 and the second closed end 1102. Based on this, the inlet connector 140 and the outlet connector 150 can be prevented from protruding from the first closed end 1101 or the second closed end 1102 along the axial direction of the sleeve 110. This facilitates further reducing the length of the separation column 100 along the axial direction of the sleeve 110, improving the structural compactness of the separation column 100, and providing a better foundation for strontium [ 90 Sr]-Yttrium[ 90 The miniaturization and portability of the Y generator provide more favorable conditions.

[0105] In this technical solution, the distance between the inlet end of the inlet connector 140 and the first closed end 1101 in the axial direction of the sleeve 110 can be set to be less than or equal to the distance between the inlet port 1103 and the first closed end 1101 in the axial direction of the sleeve 110. Based on this, the inlet connector 140 can be inclined to extend from the outer peripheral wall of the sleeve 110 towards the first closed end 1101. Thus, when the separation column 100 is placed vertically, the inlet end of the inlet connector 140 can be in a relatively high position, which makes it easier for operators to assemble pipe fittings on the inlet connector 140 and improves the installation convenience of the separation column 100 in practical applications.

[0106] In this technical solution, the distance between the liquid outlet end of the liquid outlet connector 150 and the first closed end 1101 in the axial direction of the sleeve 110 can be set to be less than or equal to the distance between the liquid outlet 1104 and the first closed end 1101 in the axial direction of the sleeve 110. Based on this, the liquid outlet connector 150 can be inclined to extend from the outer peripheral wall of the sleeve 110 towards the first closed end 1101. Thus, when the separation column 100 is placed vertically, the liquid outlet end of the liquid outlet connector 150 can be in a relatively high position, which makes it easier for operators to assemble pipe fittings on the liquid outlet connector 150 and improves the installation convenience of the separation column 100 in practical applications.

[0107] It is understandable that, in practical applications, one, two, or all of the three settings proposed in this technical solution can be used.

[0108] Such as 2 and Figure 4 As shown, in some examples, the length of the first inner cavity 1105 in the axial direction of the sleeve 110 is greater than or equal to the length of the second inner cavity 1106 in the axial direction of the sleeve 110.

[0109] In this technical solution, the length of the first inner cavity 1105 in the axial direction of the sleeve 110 can be set to be greater than or equal to the length of the second inner cavity 1106 in the axial direction of the sleeve 110. Based on this, with a fixed structural size of the sleeve 110, the volume of the first inner cavity 1105 can be increased, thereby ensuring the maximum filling amount of adsorbent in the first inner cavity 1105 and providing a guarantee for the separation effect of the separation column 100.

[0110] Understandably, in practical applications, the filter plate 120 can be arranged close to the second closed end 1102 so that the length of the first inner cavity 1105 in the axial direction of the sleeve 110 is greater than the length of the second inner cavity 1106 in the axial direction of the sleeve 110.

[0111] like Figures 1 to 15 As shown, a strontium […] is proposed according to a second aspect of the embodiments of this disclosure. 90 Sr]-Yttrium[ 90The generator includes: a housing assembly 200 having an installation space 2101; a first container 300 disposed within the installation space 2101; a second container disposed within the installation space 2101 for containing a rinsing solution; a power assembly 500 disposed within the installation space 2101, the liquid input end of the power assembly 500 being connected to the second container; a shielding assembly 600 disposed within the installation space 2101, the shielding assembly 600 having a receiving cavity 6001; and a plurality of separation columns 100 as described in any of the first aspects above disposed within the receiving cavity 6001, the plurality of separation columns 100 being connected in series between the liquid output end of the power assembly 500 and the first container 300; wherein the power assembly 500 is used to drive the rinsing solution in the second container to flow towards the separation columns 100.

[0112] The strontium provided in this embodiment of the disclosure 90 Sr]-Yttrium[ 90 The Y] generator includes the aforementioned housing assembly 200, a first container 300, a second container, a power assembly 500, a shielding assembly 600, and a plurality of separation columns 100 as described in any of the first aspects above. The housing assembly 200 forms an installation space 2101, and in practical applications, the housing assembly 200 can serve as a strontium [ 90 Sr]-Yttrium[ 90 The Y] generator housing is used to provide structural protection for other components within the mounting space 2101 and to reduce strontium [ 90 Sr]-Yttrium[ 90 The radiation impact of the generator on the external environment; the first container 300, the second container, the power component 500 and the shielding component 600 are all arranged in the installation space 2101, and multiple separation columns 100 are arranged in the receiving cavity 6001 of the shielding component 600. The multiple separation columns 100 are connected in series between the liquid output end of the power component 500 and the first container 300, and the liquid input end of the power component 500 is connected to the second container. When the power component 500 is running, it can drive the elution solution in the second container to flow to the separation column 100. Correspondingly, the elution solution flows along the series path of the multiple separation columns 100, and can interact with the adsorbent and liquid medium in the corresponding separation column 100 during the flow through the multiple separation columns 100. The liquid medium discharged from the separation column 100 at the downstream end of the series path can further flow into the first container 300 for collection by the first container 300. It can be understood that the aforementioned elution solution is suitable for eluting yttrium adsorbed on the adsorbent. 90 Y]; Before starting the aforementioned power assembly 500, if the aforementioned adsorbent has been treated with yttrium [ 90 Strontium of Y] 90 When the Sr] solution is fed onto the column, during the process of the aforementioned elution solution flowing through each separation column 100, the yttrium [Sr] within the corresponding separation column 100 can be removed.90 Y] is washed out into the first container 300, and correspondingly, the liquid medium collected in the first container 300 may be yttrium [ 90 Y] solution.

[0113] Based on this, the strontium […] provided in the embodiments of this disclosure 90 Sr]-Yttrium[ 90 The Y] generator can obtain yttrium relatively easily. 90 [Y] solution, and can utilize multiple separation columns 100 to reduce strontium [ 90 The risk of Sr] leakage, ensuring yttrium[ 90 The purity and quality of the Y] solution, and based on the aforementioned arrangement of the separation column 100, multiple separation columns 100 are suitable for radial arrangement within the shielding assembly 600 and series assembly, which helps to reduce the volume of the shielding assembly 600 and reduce the strontium [ 90 Sr]-Yttrium[ 90 The assembly difficulty of the Y] generator increases the strontium [ 90 Sr]-Yttrium[ 90 The miniaturization and portability of the Y] generator are beneficial for yttrium [Y] generation in practical applications. 90 The on-site acquisition of the Y] solution reduces the amount of yttrium [ 90 The transportation cost of the Y solution.

[0114] Understandably, in practical applications, the liquid output end of the power assembly 500 and the liquid inlet 1103 of the separation column 100 located upstream in the series path among the multiple separation columns 100 can be connected via a PEEK pipe (not shown in the figure) to establish the connection between the liquid output end of the power assembly 500 and the multiple separation columns 100 while ensuring the acid resistance and radiation resistance of the connecting pipe, which is beneficial for reducing strontium [ 90 Sr]-Yttrium[ 90 The risk of liquid leakage from the Y] generator; similarly, among the multiple separation columns 100, the outlet 1104 of the separation column 100 located at the downstream end of the series path can also be connected to the first container 300 via a PEEK pipe (not shown in the figure), and the liquid input end of the power assembly 500 can also be connected to the second container via a PEEK pipe. For example, considering the convenience of connecting the PEEK pipe to the first container 300 and the second container, strontium [ 90 Sr]-Yttrium[ 90 The Y] generator may also include two double-ended pins 290, one of which has its output end detachably inserted into the first container 300 and its input end connected to a PEEK tube corresponding to the first container 300, and the other double-ended pin 290 has its input end detachably inserted into the second container and its input end connected to a PEEK tube corresponding to the second container.

[0115] It should be noted that, Figures 5 to 15The second container is not shown. It can be understood that the aforementioned second container is suitable for containing the rinsing solution and for inserting the double-headed needle 290. The specific structural form is not limited here.

[0116] It is understandable that, in practical applications, both the aforementioned housing assembly 200 and the aforementioned shielding assembly 600 can be configured as openable and closable structures to facilitate the opening or closing of the aforementioned installation space 2101 and receiving cavity 6001. This facilitates the disassembly and maintenance of the power assembly 500, the first container 300, the second container, the shielding assembly 600, and the separation column 100, and is beneficial for further improving the performance of strontium […]. 90 Sr]-Yttrium[ 90 The ease of use of the Y generator.

[0117] Understandably, in practical applications, considering the ease of control of the power component 500, strontium [ 90 Sr]-Yttrium[ 90 The generator may also include a control panel disposed on the outer wall of the housing assembly 200. The control panel is signal-connected to the power assembly 500 and is used to control the start / stop status and operating parameters of the power assembly 500. The aforementioned operating parameters may include, but are not limited to, output pressure, output flow rate, input pressure, input flow rate, etc.

[0118] Understandably, by locating both the power assembly 500 and the shielding assembly 600 within the installation space 2101, and by placing the separation column 100 within the shielding assembly 600, the need for operators to handle strontium [ 90 Sr]-Yttrium[ 90 The radiation dose received by the Y generator.

[0119] It is understood that the series assembly of the aforementioned multiple separation columns 100 refers to the sequential connection of the multiple separation columns 100 in the flow path, that is, the multiple separation columns 100 are arranged in sequence according to a certain path. Among two adjacent separation columns 100 on the path, the liquid outlet 1104 of one is connected to the liquid inlet 1103 of the other. The liquid inlet 1103 of the separation column 100 located at the upstream end of the path can be connected to the liquid output end of the power component 500, and the liquid outlet 1104 of the separation column 100 located at the downstream end of the path can be connected to the first container 300.

[0120] Taking the number of separation columns 100 as an example, such as Figure 13As shown, both separation columns 100 can be disposed inside the shielding assembly 600, which is used to provide radioactive shielding for the separation columns 100. The axes of the two separation columns 100 can be parallel to each other, and the two separation columns 100 can be arranged radially at intervals along the sleeve 110 to reduce the spatial distribution range of the multiple separation columns 100 when arranged. The outlet 1104 of one of the two separation columns 100 can be connected to the inlet 1103 of the other through a connecting pipe (not shown in the figure) to form a series relationship between the two. In practical applications, the second closed ends 1102 of the two separation columns 100 can be arranged approximately flush so that when the two separation columns 100 are placed vertically, their heights are similar, thereby reducing the height difference between the inlet 1103 and outlet 1104 of the two separation columns 100, facilitating the assembly and connection of the aforementioned connecting pipe, and reducing the number of bends in the aforementioned connecting pipe.

[0121] It should be noted that the aforementioned first inner cavity 1105 may be filled with the aforementioned adsorbent, which may be, but is not limited to, an adsorbent capable of selectively adsorbing strontium. 90 Sr] or yttrium 90 Ion exchange resin adsorbents or macroporous adsorption resin adsorbents, etc., can be used in practical applications. In these applications, the adsorbents can be wet-filled into the first inner cavity 1105, and the filling quantity can be set according to actual needs. After filling the first inner cavity 1105 of the multiple separation columns 100 with adsorbent, the multiple separation columns 100 can be connected in series using connecting pipes. Then, an activation solution is injected into the separation column 100 located upstream of the series path, so that the activation solution flows sequentially through the multiple separation columns 100 in the series path, thereby activating the adsorbents within the multiple separation columns 100. After activating the multiple separation columns 100, an upper column solution can be injected into the separation column 100 located upstream of the series path, so that the upper column solution flows sequentially through the multiple separation columns 100 in the series path. The aforementioned upper column solution can contain yttrium […]. 90 Strontium of Y] 90 Sr] solution, for example, but not limited to strontium[ 90 Sr]-Yttrium[ 90 In the equilibrium solution, as the solution flows through each separation column 100, the adsorbent within each separation column 100 can target the strontium in the solution. 90 Sr] or yttrium 90 Y] is adsorbed to allow strontium[ 90 Sr] and yttrium 90 [Y] separation, the column loading process can be carried out in a radioactive shielded container; after the column loading is completed and strontium [Y] is reached at 100 on each separation column. 90 Sr]-Yttrium[ 90Before the decay equilibrium of yttrium [Y], a rinsing solution can be injected into the separation column 100 located at the upstream end of the series path to rinse the liquid medium in each separation column 100, reduce interfering components in the liquid medium in each separation column 100, and help ensure the subsequent acquisition of yttrium [Y]. 90 The purity of the Y] solution; after the aforementioned rinsing process is completed, multiple separation columns 100 can be placed inside the shielding assembly 600 to reduce strontium [ 90 Sr]-Yttrium[ 90 The radiation effect of the Y] generator on the surrounding environment can then be mitigated, and the aforementioned shielding component 600 can be transferred to the strontium [ 90 Sr]-Yttrium[ 90 The assembly line for the Y] generator, and with strontium[ 90 Sr]-Yttrium[ 90 Assemble and connect the other components of the Y] generator to complete the strontium [ 90 Sr]-Yttrium[ 90 Assembly of the Y] generator. Using the aforementioned strontium [ 90 Sr]-Yttrium[ 90 Y] generator acquires yttrium[ 90 When the Y] solution is in use, the power assembly 500 can be used to inject the elution solution into the separation column 100 located at the upstream end of the series path, so that the aforementioned elution solution can remove the yttrium [] in each separation column 100. 90 Y] is carried out, and correspondingly, the liquid discharged from the separation column 100 located at the downstream end of the series path can be collected to realize the separation of yttrium[ 90 The acquisition of the Y] solution. Furthermore, based on the method of setting up multiple separation columns 100 in series, it is also possible to perform strontium […] in practical applications. 90 Sr] and yttrium 90 Multiple separations of Y] reduce strontium[ 90 The risk of Sr] leakage increases the amount of yttrium obtained. 90 The purity and quality of the Y solution.

[0122] It is understandable that the types, concentrations, and amounts of the aforementioned activation solution, column loading solution, and elution solution, as well as the types, particle sizes, and amounts of the aforementioned adsorbents, can all be set according to actual needs.

[0123] It is understandable that the type and adsorption capacity of the adsorbents packed in the multiple separation columns 100 in the series path can be different. For example, the multiple separation columns 100 can be uniformly packed with adsorbents capable of selectively adsorbing strontium. 90 The adsorbent for Sr is either filled with a selective adsorbent for yttrium [Sr], or the adsorbent is filled with a material capable of selectively adsorbing yttrium. 90 The adsorbent for [Y], or a portion of the separation column 100, is filled with an adsorbent capable of selectively adsorbing strontium [Y]. 90The adsorbent is Sr, and another part of the separation column 100 is filled with yttrium […]. 90 The adsorbent is Y; preferably, the separation column 100 located downstream of the series path can be filled with an adsorbent capable of selectively adsorbing strontium [Y]. 90 Sr] adsorbent, to avoid Sr[ 90 Sr] leakage. Accordingly, the type of the aforementioned elution solution can be selected based on the actual situation of the aforementioned adsorbent.

[0124] For example, at least one separation column 100 in the series path may be filled with an adsorbent for adsorbing interfering components, thereby facilitating the purification of the liquid medium flowing through the separation column 100, for obtaining yttrium [ 90 The purity and quality of the Y] solution are guaranteed; the aforementioned interfering components may be, but are not limited to, non-strontium [ 90 Sr] and yttrium 90 Inorganic ions and organic fragments of Y].

[0125] Taking the aforementioned series-connected separation columns 100 as an example, and with an effective volume of 100 greater than or equal to 5 mL and less than or equal to 12 mL, two optional combinations of the aforementioned solutions and adsorbents are provided below:

[0126] (1) The upstream separation column 100 is filled with 4.0 g of phosphate ester resin particles as adsorbent; the downstream separation column 100 is filled with 1.0 g of amide-ether resin particles as adsorbent; the activation solution is 10 mL of 0.1 mol / L nitric acid solution; the column loading solution is a 10 mL solution of 0.1 mol / L nitric acid with an activity of 50 mCi, containing 10 mL of strontium nitrate (Strontium-90); after the column loading is completed and the Strontium [ 90 Sr]-Yttrium[ 90 The elution solution used during the elution process before the decay equilibrium of yttrium [Y] was 20 mL of 3.0 mol / L nitric acid solution; in obtaining yttrium [ 90 The rinsing solution used in the Y] solution process is nitric acid solution, and the amount and concentration can be set according to actual needs.

[0127] (2) Both separation columns 100 can be filled with 5.0 g of crown ether resin particles as adsorbent; the activation solution is 10 mL of 0.1 mol / L nitric acid solution; the loading solution is a 10 mL solution of strontium nitrate (strontium-90) with an activity of 50 mCi, and a system of 4.0 mol / L nitric acid; after loading is completed and strontium […] is reached in each separation column 100… 90 Sr]-Yttrium[ 90 The elution solution used during the elution process before the decay equilibrium of yttrium [Y] was 20 mL of 4.0 mol / L nitric acid solution; in obtaining yttrium [90 The rinsing solution used in the Y] solution process is nitric acid solution, and the amount and concentration can be set according to actual needs.

[0128] It is understandable that when strontium [ 90 Sr]-Yttrium[ 90 After the Y] generator is assembled, it can be left for about 5 days to allow the strontium [ 90 Sr]-Yttrium[ 90 Y] is used after decay equilibrium.

[0129] like Figures 5 to 10 As shown, in some examples, the housing assembly 200 includes: a cylindrical portion 210 having an installation space 2101, a cylindrical opening 2102 at the top of the cylindrical portion 210, and an operation opening 2103 on the side wall of the cylindrical portion 210; a cover portion 220 detachably disposed on the cylindrical portion 210 for opening or covering the cylindrical opening 2102; a door portion 230 hinged to the cylindrical portion 210 for opening or covering the operation opening 2103; a first bracket 240 disposed within the installation space 2101, the first bracket 240 being arranged along the height direction of the cylindrical portion 210 between the operation opening 2103 and the cylindrical opening 2102, and a power assembly 500 disposed on the first bracket 240; and a second bracket 250 disposed within the installation space 2101, and a shielding assembly 600 disposed on the second bracket 250; wherein, both the first container 300 and the second container are arranged corresponding to the operation opening 2103.

[0130] In this technical solution, the housing assembly 200 may include the aforementioned cylindrical portion 210, cover portion 220, door portion 230, first bracket 240, and second bracket 250. Based on the aforementioned arrangement, the housing assembly 200 can use the first bracket 240 to fix the power assembly 500 along the height direction of the cylindrical portion 210 between the operating port 2103 and the cylindrical opening 2102, so that while the cylindrical portion 210 provides structural protection for the power assembly 500, the first bracket 240 and the power assembly 500 do not obstruct the operating port 2103; correspondingly, the first container 300 and the second container are both arranged corresponding to the aforementioned operating port 2103, and the door portion 230 is used to open or cover the operating port 2103, thereby facilitating the operator's use of strontium [ 90 Sr]-Yttrium[ 90 During the Y] generator process, the operation port 2103 is opened and closed through the door body 230, and the first container 300 and the second container are operated through the operation port 2103, which is beneficial to further improve the strontium [ 90 Sr]-Yttrium[ 90 The Y] generator improves ease of use; the housing assembly 200 can also utilize the second bracket 250 to support the shielding assembly 600, thereby enhancing the stability of the shielding assembly 600 and the separation column 100, providing a stable environment for strontium [90 Sr]-Yttrium[ 90 The safety and reliability of the Y] generator are guaranteed; when maintenance of components within the installation space 2101 is required, the cover 220 can be removed to open the cylinder opening 2102, thereby facilitating operation of the components within the installation space 2101 by the operator; in strontium[ 90 Sr]-Yttrium[ 90 When the generator is in an idle or running state, the cover 220 and the door 230 can be used to cover the cylinder opening 2102 and the operating opening 2103 respectively, to isolate the installation space 2101 from the external environment, thereby reducing strontium [ 90 Sr]-Yttrium[ 90 The radiation impact of the Y generator on the external environment.

[0131] In some feasible examples, the housing assembly 200 also includes a handle 270 disposed on the cover portion 220, and a first latching connector 280 for locking and unlocking the cover portion 220 and the cylindrical portion 210. Based on the foregoing configuration, on the one hand, it facilitates the operator to assemble and disassemble the cover portion 220 by pulling the handle 270, or, when the cover portion 220 is locked to the cylindrical portion 210, to remove strontium […]. 90 Sr]-Yttrium[ 90 The overall transfer of the Y] generator is beneficial to improving the strontium [ 90 Sr]-Yttrium[ 90 Y] The ease of use of the generator; on the other hand, when the cover portion 220 and the cylinder portion 210 are locked by the aforementioned first buckle connector 280, the connection stability between the cover portion 220 and the cylinder portion 210 can be improved, reducing the risk of the cover portion 220 coming loose from the cylinder portion 210, and ensuring the airtightness of the installation space 2101.

[0132] In some feasible examples, the aforementioned power assembly 500 is detachably connected to the first bracket 240, the aforementioned shielding assembly 600 is detachably disposed on the second bracket 250, and both the aforementioned first bracket 240 and the aforementioned second bracket 250 are detachably disposed on the cylinder portion 210, thereby facilitating independent maintenance and replacement of each component in practical applications.

[0133] In some feasible examples, the power assembly 500 may include a power battery 520 and a peristaltic pump 510 electrically connected to the power battery 520. The peristaltic pump 510 has the aforementioned liquid inlet and liquid outlet. The first bracket 240 is provided with a battery mounting position and a pump mounting position. The power battery 520 and the peristaltic pump 510 are respectively mounted in the aforementioned battery mounting position and pump mounting position, so that the first bracket 240 can independently fix the power battery 520 and the peristaltic pump 510, which is beneficial to improving the regularity of component arrangement within the installation space 2101. Furthermore, during use, the peristaltic pump 510 can be powered by the power battery 520, which can improve the efficiency of strontium […]. 90 Sr]-Yttrium[ 90 The convenience of power supply for the Y] generator.

[0134] like Figure 8 and Figure 9 As shown, in some examples, the housing assembly 200 further includes: a telescopic frame 260a, with a fixed end and a free end at its two ends in the telescopic direction, the fixed end being fixedly disposed on the cylindrical portion 210, and the free end being adapted to extend or retract into the installation space 2101 through the operating port 2103; a third bracket 260b disposed on the free end, with the first container 300 detachably disposed on the third bracket 260b; and a fourth bracket 260c disposed on the free end, with the second container detachably disposed on the fourth bracket 260c.

[0135] In this technical solution, the housing assembly 200 may further include the aforementioned telescopic frame 260a, third support 260b, and fourth support 260c. Based on the aforementioned configuration, the housing assembly 200 can utilize the third support 260b and fourth support 260c to support the first container 300 and the second container respectively, which helps ensure the placement stability of the first container 300 and the second container. The telescopic frame 260a can drive the third support 260b and fourth support 260c to extend or retract into the installation space 2101. Therefore, in practical applications, it is convenient for operators to move the first container 300 and the second container outside the cylinder section 210, so that operators can operate the first container 300 and the second container in a relatively open space, which is beneficial to further improving the performance of strontium [ 90 Sr]-Yttrium[ 90 The ease of use of the Y generator.

[0136] In some feasible examples, both the third bracket 260b and the fourth bracket 260c can be provided with needle tube fixing slots, and the aforementioned double-headed needle 290 corresponds one-to-one with the aforementioned needle tube fixing slots. The double-headed needle 290 is detachably disposed in the needle tube fixing slot, thereby facilitating the use of the double-headed needle 290.

[0137] like Figures 11 to 13As shown, in some examples, the shielding assembly 600 includes: a tank portion 610 disposed within the installation space 2101; and a tank cover portion 620 detachably disposed on the tank portion 610, the tank cover portion 620 having an input pipe passage 6201 and an output pipe passage 6202. When the tank cover portion 620 is disposed on the tank portion 610, the tank portion 610 and the tank cover portion 620 form a receiving cavity 6001, and both the input pipe passage 6201 and the output pipe passage 6202 are connected to the receiving cavity 6001; wherein, both the tank portion 610 and the tank cover portion 620 are made of radioactive shielding material.

[0138] In this technical solution, the shielding assembly 600 may include the aforementioned tank portion 610 and tank cover portion 620. Based on the aforementioned configuration, the shielding assembly 600 can utilize the tank portion 610 and tank cover portion 620 to form the aforementioned receiving cavity 6001, and provide radioactive shielding for the separation column 100, which is beneficial for improving the strontium [ 90 Sr]-Yttrium[ 90 The safety and reliability of the generator; at the same time, the input pipe port 6201 and output pipe port 6202 opened on the slot cover 620 are suitable for the installation of the aforementioned PEEK pipe, which can facilitate the docking of multiple series-connected separation columns 100 with the power assembly 500 and the first container 300.

[0139] In some feasible examples, both the tank body 610 and the tank cover 620 are made of lead.

[0140] In some feasible examples, a protruding structure 6101 is formed on the top of the groove portion 610, and a groove structure 6203 is formed on the bottom of the groove cover portion 620. The protruding structure 6101 and the groove structure 6203 are adapted to each other. When the groove cover portion 620 is provided on the groove portion 610, the protruding structure 6101 is embedded in the groove structure 6203, which helps to improve the connection reliability between the groove portion 610 and the groove cover portion 620.

[0141] In some feasible examples, the shielding assembly 600 also includes a flip handle 660 disposed on the cover portion 620, and a second latching connector 670 for locking and unlocking the cover portion 620 and the tank body portion 610. Based on the aforementioned configuration, on the one hand, it is convenient for operators to disassemble and assemble the cover portion 620 by pulling the flip handle 660, or to transfer the entire shielding assembly 600 by pulling the flip handle 660 when the cover portion 620 is locked to the tank body portion 610; on the other hand, when the second latching connector 670 locks the cover portion 620 and the tank body portion 610, the connection stability between the cover portion 620 and the tank body portion 610 can be improved, reducing the risk of the cover portion 620 becoming loose from the tank body portion 610, and ensuring the structural stability of the shielding assembly 600.

[0142] In some feasible examples, the shielding assembly 600 may also include two self-sealing quick-connect fittings 650, wherein one self-sealing quick-connect fitting 650 is connected between the liquid inlet 1103 of the separation column 100 located at the upstream end of the series path and the liquid outlet of the power assembly 500, and the other self-sealing quick-connect fitting 650 is connected between the liquid outlet 1104 of the separation column 100 located at the downstream end of the series path and the first container 300, and the aforementioned self-sealing quick-connect fittings 650 are used to connect the PEEK tube at the corresponding position.

[0143] like Figure 13 As shown, in some examples, the shielding assembly 600 further includes: a first shielding layer, wherein a plurality of separation columns 100 are arranged at intervals along a preset direction in the receiving cavity 6001, the first shielding layer is disposed between two adjacent separation columns 100, and the first shielding layer is made of a radioactive shielding material; a buffer pad 640 is disposed on the inner bottom wall of the tank portion 610, and a second closed end 1102 is disposed on the buffer pad 640; wherein the preset direction is perpendicular to the axial direction of the sleeve 110.

[0144] In this technical solution, the shielding assembly 600 may further include the aforementioned first shielding layer and buffer pad 640. Based on the aforementioned configuration, the shielding assembly 600 can utilize the buffer pad 640 to support the separation column 100, which helps reduce the probability of structural damage to the separation column 100. Furthermore, the first shielding layer can be used to provide radioactive shielding between adjacent separation columns 100, which helps reduce the radioactive impact between the separation columns 100, thus protecting yttrium [ 90 The preparation effect of the Y] solution is guaranteed, and the relative positional relationship between the separation columns 100 can be limited, reducing the risk of collision between multiple separation columns 100.

[0145] In some feasible examples, the first shielding layer can be made of plexiglass.

[0146] In some feasible examples, the cushioning pad 640 can be made of silicone or plexiglass.

[0147] In some feasible examples, the shielding assembly 600 further includes a second shielding layer 630, which covers the inner wall of the tank portion 610, and the second shielding layer 630 is made of a radioactive shielding material with an atomic number lower than that of the material of the tank portion 610. For example, if the tank portion 610 is made of lead, the second shielding layer 630 may be made of plexiglass.

[0148] In some examples, the cylindrical body 210 is constructed as a multi-layer structure in the direction of the cylindrical wall thickness. The multi-layer structure includes a first wall layer, a second wall layer, and a third wall layer arranged sequentially from the inside to the outside. The installation space 2101 is enclosed by the first wall layer. The first wall layer is made of a flexible material, and the second and third wall layers are made of different radioactive shielding materials. The atomic number of the material of the second wall layer is less than the atomic number of the material of the third wall layer.

[0149] In this technical solution, the cylindrical portion 210 can be constructed as the aforementioned multi-layer structure. Based on the aforementioned configuration, the cylindrical portion 210, from the inside to the outside of the mounting space 2101, can be composed of a first wall layer, a second wall layer, and a third wall layer arranged sequentially. Furthermore, based on the material limitations of the aforementioned first, second, and third wall layers, the cylindrical portion 210 can utilize the first wall layer, which has good flexibility and cushioning properties, to support other components within the mounting space 2101, thereby reducing the impact on the components within the mounting space 2101 during use and reducing strontium […]. 90 Sr]-Yttrium[ 90 The risk of strontium [Y] generator malfunction or damage can be mitigated by using the second wall layer with a lower atomic number and the third wall layer with a higher atomic number to provide radioactive shielding for components inside the installation space 2101, which is beneficial for further reducing strontium [ 90 Sr]-Yttrium[ 90 The radiation impact of the Y] generator on the external environment is strontium [ 90 Sr]-Yttrium[ 90 The safety and reliability of the Y generator are guaranteed.

[0150] Similarly, the aforementioned cover portion 220 and door portion 230 can also be multi-layered structures. The cover portion 220 includes a first cover layer, a second cover layer, and a third cover layer stacked along the thickness direction. The second cover layer is located between the first cover layer and the third cover layer, and the first cover layer is used to cover the cylinder opening 2102. The door portion 230 includes a first door panel layer, a second door panel layer, and a third door panel layer stacked along the thickness direction. The second door panel layer is located between the first door panel layer and the third door panel layer, and the first door panel layer is used to cover the operating opening 2103. The aforementioned first cover layer and the aforementioned second cover layer are made of flexible material. The aforementioned second cover layer and the aforementioned second door panel layer are made of a first shielding material. The aforementioned third cover layer and the aforementioned fourth cover layer are made of a second shielding material. The first shielding material and the second shielding material are suitable for radioactive shielding, and the atomic number of the first shielding material is lower than the atomic number of the second shielding material.

[0151] For example, the aforementioned flexible material may be, but is not limited to, silicone; the aforementioned material of the second wall layer and the first shielding material may be, but is not limited to, plexiglass; and the aforementioned material of the third wall layer and the second shielding material may be, but is not limited to, stainless steel.

[0152] like Figure 14 and Figure 15 As shown, the first container 300 may include a first canister 310, a first canister cap 320, a second canister 330, a second canister cap 340, a silicone pad 350, and a vial (not shown in the figure). The first canister 310 is threadedly connected to the first canister cap 320, and the second canister 330 is threadedly connected to the second canister cap 340. The first canister 310 is fitted over the second canister 330, and the first canister cap 320 is fitted over the second canister cap 340. The silicone pad 350 is disposed on the inner bottom wall of the second canister 330. The vial is disposed on the silicone pad 350 and located inside the second canister 330. The first container 300 has a pinhole penetrating the first canister cap 320 and the second canister cap 340. The pinhole is used to insert a double-ended needle 290. The mouth of the vial is arranged correspondingly to the needle opening, so that the double-ended needle 290 can be inserted into the mouth of the vial through the needle opening to facilitate the insertion of yttrium [ 90 The Y] solution is introduced into a vial for collection, and based on the aforementioned setup, the first container 300 can enhance the effect of collecting yttrium. 90 The radioactive shielding effect of the Y solution.

[0153] Furthermore, due to the strontium [provided in the embodiments of this disclosure] 90 Sr]-Yttrium[ 90 The Y] generator includes the separation column 100 as described in any of the first aspects above, and thus possesses all the beneficial effects of the separation column, which will not be elaborated here.

[0154] In this disclosure, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance; the term "multiple" refers to two or more unless otherwise expressly defined. The terms "install," "connect," "link," and "fix" should be interpreted broadly. For example, "connect" can be a fixed connection, a detachable connection, or an integral connection; "link" can be a direct connection or an indirect connection through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms in this disclosure according to the specific circumstances.

[0155] In the description of this disclosure, it should be understood that the terms "upper," "lower," "left," "right," "front," "rear," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this disclosure and simplifying the description, and do not indicate or imply that the device or unit referred to must have a specific orientation or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this disclosure.

[0156] In the description of this specification, the terms "one embodiment," "some embodiments," "specific embodiment," etc., refer to a specific feature, structure, material, or characteristic described in connection with that embodiment or example, which is included in at least one embodiment or example of this disclosure. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0157] The above are merely preferred embodiments of this disclosure and are not intended to limit this disclosure. Various modifications and variations can be made to this disclosure by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this disclosure should be included within the scope of protection of this disclosure.

Claims

1. A separation column, characterized in that, Used for separating yttrium 90 Y] and Strontium 90 Sr], the separation column includes: The sleeve has a first closed end and a second closed end at its two axial ends, and an inlet and an outlet are provided on the circumferential side of the sleeve. A filter plate is disposed inside the sleeve, dividing the interior of the sleeve into a first inner cavity and a second inner cavity. The first inner cavity and the second inner cavity are arranged along the axial direction of the sleeve. The liquid inlet communicates with the first inner cavity, which is used to contain the adsorbent for adsorbing strontium. 90 Sr] or yttrium 90 Y]; An overflow pipe is disposed inside the sleeve, the overflow pipe passes through the filter plate, one end of the overflow pipe is located in the second inner cavity, and the other end is connected to the sleeve, the overflow pipe communicates between the second inner cavity and the outlet. Along the axial direction of the sleeve, both the inlet and the outlet are located close to the first closed end.

2. The separation column according to claim 1, characterized in that, The separation column further includes: The inlet connector has an inlet hole, the inlet connector is located outside the sleeve and is arranged corresponding to the inlet, and the inlet hole is connected to the inlet; The liquid outlet connector has a liquid outlet hole. The liquid outlet connector is located outside the sleeve and is arranged corresponding to the liquid outlet. The liquid outlet hole is connected to the liquid outlet. The axial direction of both the inlet connector and the outlet connector intersects with the axial direction of the sleeve.

3. The separation column according to claim 2, characterized in that, Along the axial direction of the sleeve, both the inlet connector and the outlet connector are located between the first closed end and the second closed end; and / or The distance between the inlet end of the inlet connector and the first closed end in the axial direction of the sleeve is less than or equal to the distance between the inlet port and the first closed end in the axial direction of the sleeve; and / or The distance between the liquid outlet end and the first closed end of the liquid outlet connector in the axial direction of the sleeve is less than or equal to the distance between the liquid outlet and the first closed end in the axial direction of the sleeve.

4. The separation column according to claim 1, characterized in that, The length of the first inner cavity in the axial direction of the sleeve is greater than or equal to the length of the second inner cavity in the axial direction of the sleeve.

5. A type of strontium [ 90 Sr]-Yttrium[ 90 Y] generator, characterized in that, include: The housing assembly provides installation space. A first container is disposed within the installation space; A second container is disposed within the installation space, and the second container is used to contain the rinsing solution; A power assembly is disposed within the installation space, and the liquid input end of the power assembly is connected to the second container; A shielding assembly is disposed within the installation space, and the shielding assembly forms a receiving cavity; A plurality of separation columns as described in any one of claims 1 to 4 are disposed within the receiving cavity, and the plurality of separation columns are connected in series between the liquid output end of the power assembly and the first container; The power unit is used to drive the elution solution in the second container to flow into the separation column.

6. The strontium according to claim 5 90 Sr]-Yttrium[ 90 Y] generator, characterized in that, The housing assembly includes: The cylindrical part has the installation space, the top of the cylindrical part has a cylindrical opening, and the side wall of the cylindrical part has an operating opening; A cover portion is detachably disposed on the cylindrical portion, and the cover portion is used to open or cover the opening of the cylindrical portion; The door portion is hinged to the cylindrical portion, and the door portion is used to open or cover the operating port; A first bracket is disposed within the installation space. The first bracket is arranged between the operating port and the cylinder opening along the height direction of the cylinder portion. The power assembly is disposed on the first bracket. The second bracket is disposed within the installation space, and the shielding component is disposed on the second bracket; Both the first container and the second container are arranged corresponding to the operation port.

7. The strontium according to claim 6 90 Sr]-Yttrium[ 90 Y] generator, characterized in that, The housing assembly also includes: A telescopic frame, wherein the two ends of the telescopic frame in the telescopic direction are a fixed end and a free end, the fixed end is fixedly disposed on the cylindrical part, and the free end is adapted to extend or retract into the installation space through the operating port; A third support is provided at the free end, and the first container is detachably provided on the third support; A fourth support is provided at the free end, and the second container is detachably provided on the fourth support.

8. The strontium according to claim 5 90 Sr]-Yttrium[ 90 Y] generator, characterized in that, The shielding component includes: The groove portion is disposed within the installation space; The trough cover is detachably disposed on the trough body. The trough cover has an inlet for an input pipe and an outlet for an output pipe. When the trough cover is disposed on the trough body, the trough body and the trough cover form the receiving cavity. The inlet for an input pipe and the outlet for an output pipe are both connected to the receiving cavity. Both the tank body and the tank cover are made of radioactive shielding material.

9. The strontium according to claim 8 90 Sr]-Yttrium[ 90 Y] generator, characterized in that, The shielding component also includes: A first shielding layer is provided, wherein a plurality of the separation columns are arranged at intervals along a predetermined direction within the receiving cavity, and the first shielding layer is disposed between two adjacent separation columns, and the first shielding layer is made of a radioactive shielding material; A buffer pad is disposed on the inner bottom wall of the tank body, and the second closed end is disposed on the buffer pad; The preset direction is perpendicular to the axial direction of the sleeve.

10. The strontium according to claim 6 90 Sr]-Yttrium[ 90 Y] generator, characterized in that, The cylindrical body is constructed as a multi-layer structure in the direction of the cylindrical wall thickness. The multi-layer structure includes a first wall layer, a second wall layer and a third wall layer arranged sequentially from the inside to the outside. The installation space is enclosed by the first wall layer. The first wall layer is made of a flexible material, the second wall layer and the third wall layer are made of different radioactive shielding materials, and the atomic number of the material of the second wall layer is less than the atomic number of the material of the third wall layer.

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