Amido polylactic acid as well as preparation method, application and application method thereof

By preparing amide-based polylactic acid (PLA) using PLA, oxidants, dicarboxylic acid compounds, and zinc-rare earth bimetallic organic framework catalysts to form amide groups, the brittleness problem of PLA is solved, and amide-based PLA degradable membrane materials with high heat resistance and chemical stability are realized, which are suitable for biomedical applications.

CN121517686APending Publication Date: 2026-02-13JIANGSU SHENTAI SCI & TECH DEV
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Patent Information

Application Number
CN202511986847.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-12-26
Publication Date
2026-02-13

AI Technical Summary

Technical Problem

Polylactic acid (PLA) is brittle, which limits its application in many fields. It needs to be modified to improve its heat resistance, chemical stability and biocompatibility.

Method used

The performance of polylactic acid (PLA) is improved by esterification of PLA, oxidant, dicarboxylic acid compound and hydroxyl-containing acyl chloride monomer using zinc-rare earth bimetallic organic framework catalyst (Zn/Ce-MOF) to form amide groups.

Benefits of technology

The prepared amide-based polylactic acid degradable membrane material has high heat resistance, chemical stability and antibacterial properties, making it suitable for biomedical applications.

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Abstract

The invention discloses amido polylactic acid as well as a preparation method, application and an application method thereof. The amido polylactic acid is prepared from polylactic acid, an oxidizing agent, a dicarboxyl amine compound, a hydroxyl-containing acyl chloride monomer and a catalyst. The preparation method comprises the following steps: firstly, respectively preparing a dihydroxy amide monomer and polylactic acid with carboxyl at two ends, then esterifying the dihydroxy amide monomer and the polylactic acid to obtain an amido polylactic acid fiber with an amido group, and blending the amido polylactic acid fiber with a polyethylene fiber to prepare the amido polylactic acid degradation film material. According to the invention, amide groups are introduced into polylactic acid molecules through a chemical method, so that the polylactic acid is endowed with new performance, the heat resistance, chemical stability, biocompatibility and the like of the polylactic acid can be improved, and the formed amido polylactic acid degradable film material has the characteristics of degradability and antibacterial property, is relatively high in heat resistance and mechanical property, and can be widely applied to the field of degradable film materials. The method can be widely applied to the biomedical field.
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