Method for combined control of multiple cell centrifugal devices

Abstract

The invention discloses a combined control method for multiple cell centrifugal devices. A controller sends preset process parameters to the multiple cell centrifugal devices; each piece of cell centrifugal equipment receives and executes preset process parameters; when the process parameters of one cell centrifugal device are adjusted, the cell centrifugal device sends an operation signal and the adjusted process parameters to the controller; after the controller receives the adjusted technological parameters and the operation signals, the adjusted technological parameters are used as new preset technological parameters to be sent to the multiple cell centrifugal devices, and each cell centrifugal device receives and executes the new preset technological parameters. The invention provides a combined control method which is convenient to operate and can remotely and synchronously control the technological process of a plurality of cell centrifugal devices.

Description

Technical Field

[0001] This invention belongs to the field of joint control of cell centrifugation equipment, specifically relating to a method for joint control of multiple cell centrifugation devices. Background Technology

[0002] In the process of biological cell culture, it is necessary to continuously add culture medium containing cell growth factors and nutrients, as well as oxygen, air, and carbon dioxide, to the cells to promote cell growth. When cell culture is complete, the proliferated cells need to undergo "cell fluid concentration" to remove excess culture medium and metabolic waste, facilitating subsequent cell cryopreservation. Due to limitations in cell concentration technology, the production efficiency of a single machine cannot meet the demands of large-scale cell preparation. Therefore, multiple cell centrifuges need to operate in conjunction, allowing the cell preparation volume to be controlled by increasing or decreasing the number of machines operating simultaneously. This requires the ability to jointly control multiple cell centrifuges, ensuring consistent process parameters across the machines, and monitoring the combined operating status of multiple machines in real time.

[0003] Therefore, there is an urgent need for a joint control method that is easy to operate and can achieve remote and synchronous control of the process flow of multiple devices. Summary of the Invention

[0004] To address the aforementioned technical problems, this invention improves upon existing technologies and optimizes the joint control of multiple novel cell therapy devices. The specific solution is as follows: A method for the joint control of multiple cell centrifugation devices, characterized in that the method includes the following steps: The controller sends preset process parameters to multiple cell centrifuges; Each cell centrifuge receives and executes preset process parameters; When the process parameters of one of the cell centrifuge devices are adjusted, that cell centrifuge device sends the operation signal and the adjusted process parameters to the controller. After receiving the adjusted process parameters and operation signals, the controller sends the adjusted process parameters as new preset process parameters to multiple cell centrifuges. Each cell centrifuge receives and executes the new preset process parameters.

[0005] Furthermore, the controller includes the control and monitoring of task allocation, process status, and production equipment status of the entire control terminal, and completes the statistical analysis of process data of the production system.

[0006] Furthermore, each cell centrifuge unit has the capability to independently complete its assigned parallel processing task for the sample volume.

[0007] Furthermore, the process parameters include, but are not limited to, at least one of the following: sample size, product quantity, centrifugal force, pump speed, circulation volume, and pipeline pressure.

[0008] Preferably, the process parameters of the cell centrifugation equipment are manually adjusted by the operator according to actual needs.

[0009] Furthermore, based on the needs of the cell preparation production system, the controller classifies the process parameters contained in the production system and analyzes the equipment status in the production system corresponding to different data types; based on the data analysis results, the data is fed back to the controller for active intervention in the process of the cell centrifugation equipment.

[0010] Furthermore, based on the actual sample size, the process parameters are input, and the controller distributes the operation instructions to each online cell centrifugation device through broadcast mapping.

[0011] Preferably, the process data of a single cell centrifugation device during the operation of the production system is automatically fed back to the controller for classification and statistics.

[0012] Furthermore, the controller includes operation control, process status, equipment status, and equipment alarms. Operation control includes equipment operation, equipment self-test, and input of process parameters; process status includes the process parameters of each piece of equipment and the number of online equipment; equipment status includes the detailed operating process parameters of the currently selected equipment; equipment alarms indicate abnormal equipment failures that occur during equipment operation.

[0013] Preferably, each cell centrifuge device is equipped with a fault sensor. The fault sensor detects equipment malfunctions, generates fault information, packages and transmits the fault information for analysis.

[0014] Furthermore, the data collection process includes protocol encapsulating data information from process data, operation processes, equipment status, and equipment alarms, then parsing the encapsulated data information through connection management, and finally performing statistical analysis.

[0015] Preferably, the data collection information is marked as an event for equipment / process management, and then transmitted to the controller for logic control at the control end.

[0016] Furthermore, the controller is connected to the device containing multiple cell centrifugation devices via a TCP / IP network protocol, employing a master / slave mode.

[0017] Preferably, the controller acts as the master, the devices act as slaves, and multiple online cell centrifuge devices on the device side constitute multiple subsystems; data information is actively pushed from the slave to the master via heartbeat data. This structure enables dynamic task allocation, avoids overloading of a single device, optimizes resource utilization, and improves overall response speed and quality.

[0018] The master / slave mode can effectively utilize network bandwidth and provide a clear data flow for the entire system. It not only simplifies the complexity of network communication and reduces data redundancy, but also helps ensure the orderly transmission of data.

[0019] Furthermore, the heartbeat data includes the status of the cell centrifugation equipment in operation and process data information; after the subsystem connects to the master, the heartbeat data is triggered; the master, through the information sent by the slave, classifies and statistically analyzes the information to determine the process progress of the system, as well as the connection status and equipment operation status of the subsystem.

[0020] Preferably, by analyzing heartbeat data, potential problems can be identified in advance. Abnormal changes in heartbeat data can indicate that an impending device failure can be detected, allowing for preventative measures to avoid unexpected system interruptions. The heartbeat data mechanism simplifies the interaction logic between master and slave systems, reduces the complexity of system design and maintenance, and facilitates implementation and expansion.

[0021] Furthermore, each cell centrifuge device sends actual operating data to the controller at preset intervals.

[0022] The controller logic automatically checks the actual operating data according to the process management rules, analyzes the status of the production equipment based on the check results, and obtains updated process data.

[0023] Furthermore, the controller can analyze the operating status of a single cell centrifugation device by analyzing changes in process data.

[0024] Furthermore, the controller receives actual operating condition data and compares it with preset process parameters to determine whether the cell centrifugation equipment is in normal or abnormal condition.

[0025] Furthermore, when any cell centrifuge device is in an abnormal state, the controller sends a shutdown command to all cell centrifuge devices.

[0026] Preferably, when the actual operating data of any cell centrifuge device does not match the preset process parameters and the controller does not receive an operation signal, the cell centrifuge device is determined to be in an abnormal state.

[0027] Preferably, if the controller does not receive actual operating data from any cell centrifuge device within a preset time, it determines that the cell centrifuge device is in an abnormal state.

[0028] Furthermore, when any cell centrifuge device malfunctions, the cell centrifuge device sends a fault signal to the controller, and the controller sends a shutdown command to all cell centrifuge devices after receiving the fault signal.

[0029] Preferably, if the cell centrifugation equipment malfunctions, i.e., the main end does not detect the heartbeat data of a single subsystem, it is determined that the subsystem is disconnected from the main end, triggering a systemic failure.

[0030] Furthermore, the cell centrifugation equipment fault information is packaged and parsed, and the parsing result is transmitted to the main terminal. The main terminal cancels the ongoing process operation, generates an alarm signal, enters the alarm process, and terminates all task processes of the production system through broadcast mapping.

[0031] Furthermore, the equipment malfunctions include network anomalies, equipment damage, and equipment malfunctions.

[0032] Furthermore, the actual operating data of the cell centrifugation equipment includes, but is not limited to, at least one of the following: sample volume, product quantity, centrifugal force, pump speed, pipeline pressure, and separation cup pressure.

[0033] Furthermore, the device can adjust the process parameters of a single cell centrifuge by adjusting the process status of the device, and the cell centrifuge control will automatically upload the operating parameters to the controller.

[0034] Furthermore, after receiving the operation signal, the controller logic automatically checks and switches the process status according to the process management rules. Through the check and judgment, the process data is mapped to the other equipment through operation instructions to complete the switching of the process status.

[0035] Furthermore, the system includes a controller and multiple cell centrifugation devices, the controller being electrically connected to the multiple cell centrifugation devices.

[0036] Furthermore, each cell centrifuge device has a corresponding feed branch pipe connected to its feed end, which is connected to the main feed pipe via a branch connector. Similarly, each cell centrifuge device has a corresponding discharge branch pipe connected to its discharge end, which is connected to the main discharge pipe via a branch connector.

[0037] Preferably, the sample is prepared using a continuous flow operation at the feed end. The workload of a single cell centrifuge is automatically allocated by the controller, and the equipment's own flow monitoring unit automatically measures the input sample volume until the specified workload is completed.

[0038] Preferably, each cell centrifuge unit is equipped with its own input control valve.

[0039] Preferably, the discharge end uses the same adapter as the inlet end, with the connection direction opposite to the input direction. The discharge branch pipe is connected to the discharge main pipe, and the discharge main pipe is connected to the cell cryopreservation preparation end to perform subsequent cell dispensing and complete product collection.

[0040] Furthermore, the controller is connected to an input module and a display module.

[0041] Preferably, the input module includes a keyboard, mouse, buttons, joystick, encoder, handheld terminal, etc., for operating and executing process parameter settings and process control.

[0042] Furthermore, the display module includes an operation control display area, a process status display area, and an equipment group actual operating condition display area.

[0043] Preferably, the operation control display area is used for user operation to set process parameters and control the process, specifically including operation control of the cell centrifugation equipment, equipment self-test, and setting process parameters such as sample volume, circulation volume, centrifugal force, and pump speed of the cell centrifugation equipment.

[0044] Preferably, the process status display area is used to display the number of processes completed for each device and the device's operating status, specifically including the specific operating time and number of processes completed for the cell centrifugation device.

[0045] Preferably, the actual operating condition display area of ​​the equipment group is used to display detailed operating parameters of any currently selected equipment, specifically including parameters such as the completed sample volume, product quantity, centrifugal force of the current centrifuge cup, pump speed, and pipeline pressure.

[0046] Furthermore, the display module uses monitors, touch screens, etc., to cooperate with the graphical user interface display areas such as the operation control display area, process status display area, and equipment group actual operating parameter display area, to monitor the process completion quantity and equipment operating status of each device in real time.

[0047] Furthermore, the controller also includes a "process management module," a "data capture module," and a "page navigation module" for responding to process status, as well as for receiving remote intervention commands and sending and mapping equipment operation commands.

[0048] Preferably, the "process management module" sends the operation instructions of one of the cell centrifuge devices to the controller via heartbeat data. The controller then maps the instructions to the remaining online cell centrifuge devices, affecting the process of individual devices and all devices.

[0049] Furthermore, when the "process management module" receives operation commands from the controller and interferes with the local process, it feeds back to the "page navigation module" to synchronize the local operation page display.

[0050] Preferably, the "data capture module" is used for real-time data acquisition by the device and uploads the acquired data to the controller.

[0051] This invention provides a method for the joint control of multiple cell centrifuge devices. The entire production system monitors and controls the production process through a controller. Each cell centrifuge device executing the process is an independent and complete production system. By independently executing process operations on each cell centrifuge device and automatically feeding back the process parameters from that device to the system controller, the controller makes logical judgments and intervenes in the process operation of the remaining devices, thereby achieving the purpose of joint system control.

[0052] Compared with the prior art, the beneficial effects of the present invention include: 1) This invention provides a method for joint control of multiple cell centrifugation devices, which enables remote and synchronous joint control of the process flow of multiple cell centrifugation devices.

[0053] 2) This invention provides a method for the joint control of multiple cell centrifugation devices, which can monitor and control the process operation of the entire system through a controller, and the controller can be located anywhere on the network. Simultaneously, users can monitor the system's operating status in real time, greatly reducing limitations and increasing user convenience.

[0054] 3) This invention provides a method for the joint control of multiple cell centrifugation devices. Each individual device is an independent and complete control system with full production process control capabilities. By employing multiple individual device operation methods, the workload of the number of devices multiplied within a unit of time is completed, greatly improving production efficiency. Simultaneously, through process early warning and proactive intervention mechanisms, the safety of the entire system's process execution can be effectively ensured.

[0055] 4) This invention provides a method for joint control of multiple cell centrifugation devices. The system adopts a dynamic deployment method, and the connected operation subsystems can be configured with a corresponding number of process devices according to actual needs, which greatly increases the flexibility of the system. Attached Figure Description

[0056] The present invention will be further described below with reference to the accompanying drawings and embodiments. In the accompanying drawings: Figure 1 A topology diagram of a joint control scheme for multiple cell centrifugation devices; Figure 2 A schematic diagram of the adapter at the equipment end of a method for joint control of multiple cell centrifugation devices; Figure 3 A schematic diagram of the functional logic of a system for the joint control of multiple cell centrifugation devices; Figure 4 A schematic diagram of the controller's main control page for a method of jointly controlling multiple cell centrifugation devices; Figure 5A schematic diagram of the process control logic of a controller for a method of jointly controlling multiple cell centrifugation devices; Figure 6 This is a schematic diagram of the control logic at the device end for a method of jointly controlling multiple cell centrifugation devices.

[0057] The diagram is labeled as follows: 1-Main pipeline, 2-Sub-pipeline. Detailed Implementation

[0058] The technical solution of the present invention will be clearly and completely described below with reference to the embodiments and accompanying drawings. The described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0059] In the description of this invention, it should be understood that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicating orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, are only for the convenience of describing the invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the invention. Furthermore, the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined with "first," "second," etc., may explicitly or implicitly include one or more of that feature. In the description of this invention, unless otherwise stated, "a plurality of" means two or more.

[0060] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art will understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0061] This invention provides a method for the joint control of multiple cell centrifugation devices. The cell sample solution delivery pipeline is split, with each device performing its independent task. The concentrated final cell solution is then collected and combined to complete the preparation process. This method overcomes the limitations of cell concentration processes, where the maximum efficiency of a single device cannot meet the demands of large-scale cell preparation. The entire system utilizes multiple devices to jointly execute the process requirements. Within a given time frame, the system's operation is actively or passively adjusted based on set conditions. By increasing or decreasing the number of devices operating in conjunction with the process, the required cell preparation volume can be controlled.

[0062] The controller sends preset process parameters to multiple cell centrifuges; each cell centrifuge receives and executes the preset process parameters; the operator manually adjusts the process parameters of one of the cell centrifuges, and that cell centrifuge sends the operation signal and the adjusted process parameters to the controller; after receiving the adjusted process parameters and the operation signal, the controller sends the adjusted process parameters as new preset process parameters to multiple cell centrifuges, and each cell centrifuge receives and executes the new preset process parameters.

[0063] The acquisition, storage, use, and processing of data in the technical solution of this invention all comply with relevant regulations.

[0064] To better understand the technical solution of this invention, the following uses a specific method for the joint control of multiple cell centrifugation devices as an example to illustrate this invention.

[0065] like Figure 1 As shown, the entire system employs a design that utilizes multiple cell centrifuges operating in parallel and continuously. The system comprises a controller and the equipment itself. The user operates the controller, transmitting signals to the equipment. The input sample is then connected in parallel to multiple cell centrifuges via a main valve. Cells processed by the centrifuges enter the discharge end for final product collection.

[0066] In this embodiment, the entire system needs to connect 10 cell centrifugation devices to work together, using a 1-to-10 adapter (such as...). Figure 2 (As shown), connect the main pipeline Figure 1 At the central interface, the cell centrifuge equipment is connected to its corresponding sub-pipeline. The pipeline is divided into 10 equally spaced branch lines, with each cell centrifuge unit deployed in its corresponding branch line to complete its respective task. This connection method facilitates operator control of pipeline flow and serves a safety management function.

[0067] Controller: Used for system task allocation, system status monitoring, process operation monitoring and control management, and statistical analysis of process data. The controller includes job control, process status, equipment status, alarm mechanisms, and a main control page.

[0068] Equipment side: Composed of multiple cell centrifuges, each a complete and independent process unit capable of fulfilling its assigned tasks. Each centrifuge automatically closes its feed branch via its own input control valve, stopping operation when no more samples are input. Each unit connects to the feed end via connecting pipes, and its built-in flow monitoring unit automatically measures the input sample volume until the assigned task volume is completed. The task volume is automatically allocated by the main control unit.

[0069] Feeding end: A single input pipe is used as the main pipe 1. The main pipe 1 is divided into multiple sub-pipes 2 through branch joints. This method can make the flow rate and pressure of each sub-pipe 2 balanced, so that the control system can manage the process execution of each sub-component in a balanced manner.

[0070] Discharge end: The discharge end uses the same adapter as the feed end, with the connection direction opposite to the input direction. The discharge branch pipe is connected to the discharge main pipe, and the discharge main pipe is connected to the cell cryopreservation preparation end to perform subsequent cell dispensing and complete product collection.

[0071] The controller and the devices are connected via a TCP / IP network protocol in a master / slave mode. The controller acts as the master, and the devices act as slaves. Multiple online cell centrifuge devices on the device side constitute multiple subsystems. Data is actively pushed from the slave to the master via heartbeat data within a specified time. The heartbeat data includes device status and process data. After a subsystem connects to the master, it triggers the heartbeat data. The master, after classifying and statistically analyzing the information sent by the subsystems, determines the system's process progress, as well as the connection status of the subsystems and the operating status of the devices.

[0072] like Figure 3 As shown, the controller includes: operation control, process status, equipment status, and alarm mechanisms. The controller distributes task plans to users, encapsulates the user's task instructions, parses them, and then issues operation instructions to all cell centrifuge devices. Each cell centrifuge device operates according to the corresponding operation instructions. Multiple cell centrifuge devices operate simultaneously, collecting data from the online devices, encapsulating and uploading different data, parsing it, performing statistical analysis on the device data, and then transmitting the analysis results to the main control terminal for appropriate operations.

[0073] Example 1: Based on the input sample size, the controller maps operation commands to each online device via broadcast. The controller is connected to an input module and a display module. Input modules include keyboards, mice, buttons, joysticks, encoders, and handheld terminals, while display modules include monitors and touchscreens. Figure 4As shown, the main control page of the display module includes a job control display area, a process status display area, and an equipment group actual operating status display area. The job control display area is used for user operation and execution of process parameter settings and process control, specifically including operation control of the cell centrifuge equipment, equipment self-testing, and setting process parameters such as sample volume, circulation volume, centrifugal force, and pump speed. The process status display area displays the number of processes completed and the operating status of each device, specifically including the specific running time and number of processes completed for the cell centrifuge equipment. The equipment group actual operating status display area displays detailed operating parameters for any currently selected device, specifically including the completed sample volume, product quantity, current centrifugal force, pump speed, and pipeline pressure. Users input relevant process parameters based on the total sample volume through the input module on the main control page of the control terminal display module.

[0074] In this embodiment, a 500L concentration operation is selected. On the main control panel, the user inputs "500000" in the "Sample Volume" field of the process parameter execution box. Since the pipeline is divided into 10 equal parts, 10 cell centrifuges are used, and each device needs to complete a specified task volume of 500 / 10 = 50 liters. The product concentration rate: Based on the dynamic volume of the centrifuge cup (350 ml), the concentration rate = single cycle / 350. With a cycle volume set to 3500, the concentration rate = 3500 / 350 = 10 times. By selecting any device in the "Equipment Group" in the process status display module, detailed operating parameters of the currently selected device can be viewed. These include the completed sample volume, product volume, current centrifugal force, pump speed, pipeline pressure, and other parameters.

[0075] After the user completes the parameter settings, they can start the process by clicking the job control button on the main control page. The controller automatically distributes the set process parameters and process start commands to each online cell centrifuge device via broadcast mapping. The main control unit collects the process data actively uploaded by each cell centrifuge device, categorizes and statistically analyzes the completed sample and product quantities, and displays this data on the main control page display module. Users can view the current operating status of any device in the "Device Group" section of the main control page and can also autonomously control the system's job process through the control page. The control logic automatically monitors and judges the job progress in real time based on the process status data, and actively intervenes in the cell centrifuge device's process process by sending control commands through the network connection between the cell centrifuge device and the controller.

[0076] Example 2: Adjusting the process parameters of independent equipment to achieve process state switching. like Figure 5As shown, the system supports setting process parameters and managing process progress on independent cell centrifuge devices. When the process parameters of one cell centrifuge device are manually adjusted, that device sends the operation signal and the adjusted process parameters to the controller. Upon receiving the operation signal, the controller's logic automatically checks and determines whether the current operation is valid according to the process management rules, detects and executes the operation, and sends the adjusted process parameters as new preset process parameters to multiple cell centrifuge devices. Each cell centrifuge device receives and executes the new preset process parameters.

[0077] Specifically, instead of achieving unified control between devices, each device actively connects to the control terminal and uploads its operating status to the controller in real time via heartbeat data. Users modify commands on the cell centrifuge device's terminal, and these modifications are also sent to the controller via heartbeat data. This allows for the switching of the entire system's process state by adjusting the parameters of individual devices.

[0078] Example 3: Handling Abnormalities in Cell Centrifugation Equipment During operation, the controller can analyze changes in process data to determine the operating status of individual cell centrifuge units. Specifically, after a subsystem connects to the master unit, it triggers a heartbeat signal. The master unit then categorizes and statistically analyzes the feedback information from the subsystems to determine the overall process progress, connection status, and operating status of the subsystems. When any cell centrifuge unit in a subsystem is in an abnormal state—for example, if it sends a fault signal to the controller, fails to detect a feedback signal from a single cell centrifuge unit within a specified time, or detects that the actual operating data of a single cell centrifuge unit does not match the preset process parameters—a fault alarm is triggered. The controller determines whether the alarm is a message type affecting the system's process progress based on the reported fault type. If the determination fails, the controller logic automatically triggers a systemic fault and terminates its own process. The controller system then broadcasts a shutdown command to the remaining connected cell centrifuge units, causing them to execute the same command and stop the process progress of all units.

[0079] Example 4: Remote Synchronization Control of the System like Figure 6As shown, the entire system also includes a "process management module," a "page navigation module," and a "data capture module." Users can remotely intervene in the equipment based on the operation instructions of these three modules, and broadcast these intervention instructions to the entire system. Users can control the process of all equipment through the controller, or control the process of individual equipment. The "process management module" sends local operation instructions to the controller via heartbeat data, and the controller maps the instructions to the remaining cell centrifuge equipment. Simultaneously, the "process management module" is responsible for receiving control instructions issued by the controller, interfering with the local process, and feeding back to the "page navigation module" to synchronize the operation display on the local main control page. Meanwhile, real-time data from the equipment is collected in real time and uploaded to the controller through the "data capture module."

[0080] The above description is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. A method for joint control of a plurality of cell centrifuge apparatuses, characterized by, The method comprises the following steps: The controller sends preset process parameters to the plurality of cell centrifuge devices; Each cell centrifuge device receives and executes the preset process parameters; When the process parameters of one of the cell centrifuge devices are adjusted, the cell centrifuge device sends an operation signal and the adjusted process parameters to the controller; After receiving the adjusted process parameters and the operation signal, the controller sends the adjusted process parameters as new preset process parameters to the plurality of cell centrifuge devices, and each cell centrifuge device receives and executes the new preset process parameters.

2. The method of joint control of a plurality of cell centrifuge apparatuses according to claim 1, wherein, The process parameters include at least one of sample volume, product quantity, centrifugal force, pump speed, circulation volume, and pipeline pressure.

3. The method of joint control of a plurality of cell centrifuge apparatuses according to claim 1, wherein, The method further comprises the following steps: Each cell centrifuge device sends actual working condition data to the controller at a preset time interval; The controller receives the actual working condition data and compares the actual working condition data with the preset process parameters to determine whether the cell centrifuge device is in a normal operating state or an abnormal state, and sends a shutdown instruction to all cell centrifuge devices when any cell centrifuge device is in an abnormal state.

4. The method of joint control of a plurality of cell centrifuge apparatuses according to claim 3, wherein, The actual working condition data include at least one of sample volume, product quantity, centrifugal force, pump speed, and pipeline pressure.

5. The method of joint control of a plurality of cell centrifuge apparatuses according to claim 3, wherein, When the actual working condition data of any cell centrifuge device do not match the preset process parameters and the controller does not receive an operation signal, it is determined that the cell centrifuge device is in an abnormal state.

6. The method of joint control of a plurality of cell centrifuge apparatuses according to claim 3, wherein, When the controller does not receive actual working condition data from any cell centrifuge device within a preset time, the controller sends a shutdown instruction to all cell centrifuge devices.

7. The method of joint control of a plurality of cell centrifuge apparatuses according to claim 1, wherein, The method further comprises the following steps: When any cell centrifuge device fails, the cell centrifuge device sends a failure signal to the controller, and the controller receives the failure signal and sends a shutdown instruction to all cell centrifuge devices.

8. A joint control system for multiple cell centrifugation devices, characterized in that, The system comprises a controller and a plurality of cell centrifuge devices, the controller is electrically connected to the plurality of cell centrifuge devices, the feed end of each cell centrifuge device is one-to-one connected to a feed branch pipe, the feed branch pipe is connected to a feed main pipe through a shunt joint, the discharge end of each cell centrifuge device is one-to-one connected to a discharge branch pipe, and the discharge branch pipe is connected to a discharge main pipe through a shunt joint.

9. The multi-cell centrifuge system of claim 8, wherein the controller is configured to: The controller is connected to an input module and a display module.

10. The multi-cell centrifuge system of claim 9, wherein: The display module comprises a job control display area, a process state display area, and a device group actual working condition display area.

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