Multifunctional integrated cervical cancer screening equipment

Abstract

The invention relates to the technical field of cervical cancer screening equipment, and discloses multifunctional integrated cervical cancer screening equipment which comprises a detection box, an oscillation mechanism, four centrifugal mechanisms and a driving mechanism and further comprises linear lifting mechanisms fixedly mounted on the two side walls and the back wall in the detection box correspondingly. The oscillating mechanism is fixedly mounted at the top of the mounting plate; according to the technical scheme, the driving mechanism simultaneously drives the oscillation mechanism to operate and cooperates with the oscillation mechanism to drive the centrifugal mechanism planet to rotate; a cervical exfoliated cell sample is subjected to high-frequency oscillation treatment by utilizing an oscillation mechanism, and adhesion and aggregation states among cells are destroyed through mechanical force, so that the dispersity among the cells is improved; the centrifugal mechanism of planet rotation generates centrifugal force, and cells can be uniformly deposited on the tube wall of the centrifugal tube, so that the cells are uniformly distributed on the surface of the glass slide to form a single-layer cell layer, each cell is ensured to be independently tiled without overlapping and shielding, and the cell morphology is completely displayed.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of cervical cancer screening equipment, in particular to a multifunctional integrated cervical cancer screening equipment. BACKGROUND

[0002] Cervical cancer is one of the common malignant tumors of women, which seriously threatens the health of women. Early detection and treatment can significantly improve the survival rate and cure rate of patients, so the screening method of cervical cancer becomes the key. The traditional cervical cancer screening method usually uses Pap smear. This method mainly spreads the collected cervical cells on a glass slide and checks them under a microscope to find abnormal cells or cancer cells. The multifunctional integrated cervical cancer screening equipment and screening method with publication number CN114544301B have solved the problem that the two technologies cannot be combined. If both screening methods are to be applied simultaneously, multiple instruments are needed to cooperate with each other to achieve the purpose. Neither from the economic point of view nor from the screening efficiency can the technology meet the needs of the current busy clinical detection work. However, similar structures still have many defects in actual use. For example, the existing cervical cancer screening equipment cannot form a uniform distribution of thin layer smears on the glass slide due to the diversity of operation methods and cell collection environment when making smears. Specifically, this will cause overlapping between cells, making it difficult to accurately display the overall morphology of the cells. The distortion of cell morphology not only affects the identification of cells by doctors, but also makes it difficult to discover or diagnose early changes in cancer cells in time.

[0003] Therefore, the above technical problems need to be solved. SUMMARY

[0004] In order to overcome the shortcomings of the prior art, the present application provides a multifunctional integrated cervical cancer screening equipment to solve the problem of overlapping between cells, which makes it difficult to accurately display the overall morphology of the cells. The distortion of cell morphology affects the identification of cells by doctors.

[0005] In order to solve the above technical problems, the basic technical scheme of the present application is as follows: A multifunctional integrated cervical cancer screening equipment, comprising a detection box, an oscillation mechanism, four sets of centrifugal mechanisms and a driving mechanism, further comprising linear lifting mechanisms fixedly installed on the two side walls and the back wall inside the detection box, the front of the linear lifting mechanisms of the two side walls is fixedly installed with a dyeing mechanism and a liquid taking mechanism respectively, and the front of the linear lifting mechanism of the back wall is fixedly installed with a cell suspension dropping mechanism; a sliding groove plate is fixedly installed inside the detection box, and an installation plate is fixedly installed below the sliding groove plate. The oscillation mechanism is fixedly installed on the top of the mounting plate, and is composed of a center table, a transmission spline rod, a spline sleeve and an oscillation disc. A through hole is formed in the inner annular array of the oscillation disc, and the through hole provides an insertion position for the oscillation bottle. The spline sleeve is fixedly installed on the bottom of the oscillation disc, the transmission spline rod is movably installed in the inner part of the center table and extends to the top of the center table. The top of the transmission spline rod is connected with the oscillation disc through the spline sleeve, the bottom of the oscillation disc is annularly installed with a plurality of rollers, the outer side of the center table is fixedly installed with a first face gear disc, and the top of the center table is annularly fixedly installed with an inclined block. The driving mechanism is rotatably installed on the bottom of the mounting plate, and is composed of a driving face gear disc, a driving bevel gear, a driving motor, a double-head bevel gear part, a rotating frame, a second face gear disc and a driven face gear disc. The driven face gear disc is fixedly installed on the top of the driving face gear disc and extends to the inner part of the center table. The top of the driven face gear disc is connected with the bottom end of the transmission spline rod through the spline. The rotating frame is movably sleeved on the outer side of the center table, and the second face gear disc is fixedly installed on the top of the rotating frame. The double-head bevel gear part is rotatably installed on one side of the center table and penetrates into the inner part of the center table. One end of the double-head bevel gear part is engagedly connected with the driven face gear disc, and the other end of the double-head bevel gear part is engagedly connected with the second face gear disc. The four sets of centrifugal mechanisms are annularly installed on the top of the rotating frame, and are composed of a mounting table, an intermittent rotation assembly, a clamping table, an intermittent transmission wheel and a clamping assembly. The inner wall of the mounting table is fixedly installed with a stop block. The intermittent transmission wheel is rotatably installed on one side in the inner part of the mounting table, and one side of the intermittent transmission wheel is fixedly installed with a first bevel gear extending into the inner part of the mounting table through a shaft rod. The first bevel gear is engagedly connected with the first face gear disc. The clamping table is rotatably installed on the top of the mounting table, and the bottom of the clamping table is fixedly installed with a spline groove extending into the inner part of the mounting table. The clamping table is connected with the intermittent rotation assembly through the spline groove. The clamping assembly is installed in the inner part of the clamping table through a bearing. The top of the clamping table is clamped with a glass slide and a centrifugal tube through the clamping assembly, and the centrifugal tube is located on the top surface of the glass slide. The oscillation mechanism is driven to operate by the driving mechanism, and the two sets of linear lifting mechanisms are driven to operate. The oscillation mechanism drives the position of the four sets of centrifugal mechanisms to alternately change and rotate. The collected cervical exfoliative cell samples are subjected to oscillation treatment by the oscillation mechanism. The cells are released by oscillation, and the samples in the oscillation bottle are transferred to the centrifugal tube in the centrifugal mechanism by the linear lifting mechanism driving the lifting movement of the liquid taking mechanism. The centrifugal force generated by the rotating centrifugal mechanism makes the cells move to the wall of the centrifugal tube and uniformly deposit on the glass slide to form a single cell layer. Meanwhile, the four sets of centrifugal mechanisms alternately change the position to uniformly deposit the cells on the four glass slides. The back wall one group of linear lifting mechanism drives the cell suspension drop mechanism to drop the cell suspension on the slide glass marked with numbers; the back wall another group of linear lifting mechanism drives the dyeing mechanism to move downward to dye the cells, and the morphology of the cervical cell can be observed by using a microscope.

[0006] Preferably, the intermittent rotating assembly is composed of a rotating wheel, a linkage spline rod, a first return spring and a blocking tooth, the linkage spline rod is fixedly installed on the top of the rotating wheel, the linkage spline rod extends to the inside of the spline groove for active connection, the first return spring is movably sleeved on the outside of the linkage spline rod, the blocking tooth is fixedly installed on one side of the first return spring, and the blocking tooth is dynamically in contact with the blocking block.

[0007] Preferably, the clamping assembly is composed of a worm gear, two one-way screws, two screw sleeve frames, two clamping seats and a worm, the two one-way screws are respectively fixedly installed on the two sides of the worm gear, the two screw sleeve frames are respectively sleeved on the outside of the two one-way screws, the two clamping seats are respectively fixedly installed on the top of one side of the two screw sleeve frames, the worm is meshed with the worm gear, and one end of the worm is fixedly installed with a shaft rod extending into the inside of the clamping table.

[0008] Preferably, the linear lifting mechanism is composed of a mounting frame, a bidirectional screw rod, a screw sleeve seat, a guide rod and a servo motor, the bidirectional screw rod is rotatably installed on one side of the inside of the mounting frame, the guide rod is fixedly installed on the other side of the inside of the mounting frame, the screw sleeve seat is sleeved on the outside of the bidirectional screw rod and the guide rod, the front surface of the screw sleeve seat is fixedly installed with a bracket, the output end of the servo motor is fixedly connected with the bottom end of the bidirectional screw rod, and the servo motor is fixedly installed on the bottom of the mounting frame.

[0009] Preferably, the dyeing mechanism is composed of a storage tank and a first contact injection head, the first contact injection head is screwedly installed on the bottom of the storage tank, and the first contact injection head is embeddedly installed in the bracket on the front surface of the screw sleeve seat.

[0010] Preferably, the first contact injection head is composed of a liquid outlet pipe, a conical hole head, a second return spring and a catheter, the conical hole head is movably installed in the inside of the liquid outlet pipe, the bottom of the conical hole head is movably installed with the catheter extending out, and the second return spring is sleeved on the outside of the catheter.

[0011] Preferably, the liquid taking mechanism is composed of a telescopic rod, an electric rod and a second contact injection head, the electric rod is fixedly installed in the inside of the telescopic rod, and the second contact injection head is embeddedly installed on one end of the telescopic rod.

[0012] Preferably, the driving face gear is rotatably installed on the bottom of the mounting plate, the driving motor is fixedly installed on the bottom of the mounting plate, the driving bevel gear is fixedly connected with the output end of the driving motor through the shaft rod, and the driving bevel gear is meshed with the driving face gear.

[0013] The beneficial effects of the present application are: The technical scheme of the present application drives the oscillation mechanism to operate through the driving mechanism, and drives the centrifugal mechanism to rotate in a planetary mode in cooperation with the oscillation mechanism, uses the oscillation mechanism to perform high-frequency oscillation processing on the cervical exfoliative cell sample, destroys the adhesion and aggregation state between cells through mechanical force, improves the dispersion degree between cells, ensures that the cells are in a dispersed state when being transferred to the centrifugal tube, and enables the cells to be uniformly dispersed on the surface of the slide when being centrifuged; the centrifugal mechanism in the planetary mode generates a centrifugal force, and the cells can be uniformly deposited to the wall of the centrifugal tube, so that the cells are uniformly distributed on the surface of the slide to form a single cell layer, ensures that each cell is independently laid out without overlapping and shielding, the cell morphology can be completely displayed, the problems of missed diagnosis or misdiagnosis caused by overlapping are avoided, and doctors can more accurately observe the details of the cells, thereby improving the speed and accuracy of cervical cancer screening. BRIEF DESCRIPTION OF DRAWINGS

[0014] Figure 1 It is a schematic diagram of the overall structure in the present application; Figure 2 It is a schematic diagram of the internal structure of the detection box in the present application; Figure 3 It is a schematic diagram of the transmission connection between the driving mechanism and the oscillation mechanism and the synchronous lifting mechanism in the present application; Figure 4 It is a schematic diagram of the structure of the driving mechanism in the present application; Figure 5 It is a schematic diagram of the transmission connection between the driving mechanism and the oscillation mechanism in the present application; Figure 6 It is a schematic diagram of the internal expansion structure of the oscillation mechanism in the present application; Figure 7 It is a schematic diagram of the transmission connection between the oscillation mechanism and the centrifugal mechanism in the present application; Figure 8 It is a schematic diagram of the internal structure of the centrifugal mechanism in the present application; Figure 9 It is a schematic diagram of the structure of the intermittent rotation assembly in the present application; Figure 10 It is a schematic diagram of the structure of the clamping assembly in the present application; Figure 11 It is a schematic diagram of the transmission connection between the driving mechanism and the synchronous lifting mechanism in the present application; Figure 12 It is a schematic diagram of the structure of the synchronous lifting mechanism in the present application; Figure 13 It is a schematic diagram of the internal structure of the dyeing mechanism in the present application; Figure 14 It is a schematic diagram of the connection between the linear lifting mechanism and the liquid taking mechanism in the present application; Figure 15It is the internal structure schematic view of the liquid taking mechanism in the application.

[0015] Mark explanation: 1, detection box; 101, chute plate; 102, mounting plate; 2, oscillation mechanism; 201, center table; 202, first face gear disc; 203, transmission spline rod; 204, inclined block; 205, spline sleeve; 206, oscillation disc; 207, roller; 208, oscillation bottle; 3, centrifugal mechanism; 301, mounting table; 3011, stop block; 302, intermittent rotation assembly; 3021, rotating wheel; 3022, linkage spline rod; 3023, first return spring; 3024, stop gear; 303, clamping table; 3031, spline groove; 304, intermittent transmission wheel; 3041, first bevel gear; 305, clamping assembly; 3051, worm gear; 3052, one-way screw rod; 3053, screw sleeve frame; 3054, clamping seat; 3055, worm; 306, glass slide; 307, centrifugal tube; 4, linear lifting mechanism; 401, mounting frame; 402, bidirectional screw rod; 403, screw sleeve seat; 404, guide rod; 405, servo motor; 5, dyeing mechanism; 501, storage tank; 502, first resistance injection head; 5021, liquid outlet pipe; 5022, conical hole head; 5023, second return spring; 5024, guide pipe; 6, cell suspension dropping mechanism; 7, liquid taking mechanism; 701, telescopic rod; 702, electric rod; 703, second resistance injection head; 8, driving mechanism; 801, driving face gear disc; 802, driving bevel gear; 803, driving motor; 804, double-head bevel gear part; 805, rotating frame; 806, second face gear disc; 807, driven face gear disc. DETAILED DESCRIPTION

[0016] The following will be combined with the accompanying Figure 1 to the accompanying Figure 15 The technical solutions in the embodiments of the application are clearly and completely described. Obviously, the described embodiments are only part of the embodiments of the application, rather than all the embodiments. Based on the embodiments in the application, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the application.

[0017] A multifunctional integrated cervical cancer screening device, comprising a detection box 1, an oscillation mechanism 2, four sets of centrifugal mechanisms 3 and a driving mechanism 8, further comprising a linear lifting mechanism 4 fixedly installed on the front surface of the two side walls and the back wall in the detection box 1 respectively, the front surface of the linear lifting mechanism 4 of the two side walls is fixedly installed with a dyeing mechanism 5 and a liquid taking mechanism 7 respectively, and the front surface of the linear lifting mechanism 4 of the back wall is fixedly installed with a cell suspension dropping mechanism 6; a chute plate 101 is fixedly installed inside the detection box 1, and a mounting plate 102 is fixedly installed below the chute plate 101; The oscillation mechanism 2 is fixedly installed on the top of the mounting plate 102, and the oscillation mechanism 2 is composed of a center table 201, a transmission spline shaft 203, a spline sleeve 205 and an oscillation disc 206, a plurality of through holes are arranged in the inner annular array of the oscillation disc 206, and the through holes provide insertion positions for oscillation bottles 208; the spline sleeve 205 is fixedly installed on the bottom of the oscillation disc 206, the transmission spline shaft 203 is movably installed in the inner part of the center table 201 and extends to the top of the center table 201; the top of the transmission spline shaft 203 is connected with the oscillation disc 206 through the spline sleeve 205, a plurality of rollers 207 are annularly arranged on the bottom of the oscillation disc 206, a first face gear disc 202 is fixedly installed on the outer side of the center table 201, and an inclined block 204 is annularly fixedly installed on the top of the center table 201; The driving mechanism 8 is rotatably installed on the bottom of the mounting plate 102, and the driving mechanism 8 is composed of a driving face gear disc 801, a driving bevel gear 802, a driving motor 803, a double-head bevel gear part 804, a rotating frame 805, a second face gear disc 806 and a driven face gear disc 807, the driven face gear disc 807 is fixedly installed on the top of the driving face gear disc 801 and extends to the inner part of the center table 201, and the top of the driven face gear disc 807 is connected with the bottom end of the transmission spline shaft 203 through the spline; the rotating frame 805 is movably sleeved on the outer side of the center table 201, the second face gear disc 806 is fixedly installed on the top of the rotating frame 805, the double-head bevel gear part 804 is rotatably installed on one side of the center table 201 and penetrates into the inner part of the center table 201, one end of the double-head bevel gear part 804 is engagedly connected with the driven face gear disc 807, and the other end of the double-head bevel gear part 804 is engagedly connected with the second face gear disc 806; The four sets of centrifugal mechanisms 3 are annularly arranged on the top of the rotating frame 805, and each centrifugal mechanism 3 is composed of a mounting table 301, an intermittent rotation assembly 302, a clamping table 303, an intermittent transmission wheel 304 and a clamping assembly 305, a plurality of stop blocks 3011 are fixedly installed on the inner wall of the mounting table 301, the intermittent transmission wheel 304 is rotatably installed on one side in the inner part of the mounting table 301, a first bevel gear 3041 extending out of the inner part of the mounting table 301 is fixedly installed on one side of the intermittent transmission wheel 304 through a shaft, the first bevel gear 3041 is engagedly connected with the first face gear disc 202, the clamping table 303 is rotatably installed on the top of the mounting table 301, a spline groove 3031 extending into the inner part of the mounting table 301 is fixedly installed on the bottom of the clamping table 303, the clamping table 303 is connected with the intermittent rotation assembly 302 through the spline groove 3031, and the clamping assembly 305 is installed in the inner part of the clamping table 303 through a bearing; a plurality of glass slides 306 and centrifugal tubes 307 are clamped and installed on the top of the clamping table 303 through the clamping assembly 305, and the centrifugal tubes 307 are located on the top surface of the glass slides 306; The oscillation mechanism 2 is driven to run by the driving mechanism 8, and the two sets of linear lifting mechanisms 4 are driven to run, and the running oscillation mechanism 2 drives the four sets of centrifugal mechanisms 3 to alternately change positions and rotate by itself. The collected cervical exfoliated cell sample is subjected to oscillation treatment by the running oscillation mechanism 2, and the cells are released by oscillation; the internal sample in the oscillation bottle 208 of the oscillation mechanism 2 is transferred to the centrifugal tube 307 in the centrifugal mechanism 3 by the cooperation of the linear lifting mechanism 4 and the liquid taking mechanism 7; the cells are moved to the tube wall of the centrifugal tube 307 and uniformly deposited on the glass slide 306 by the centrifugal force generated by the self-rotation running centrifugal mechanism 3, forming a single layer of cells; at the same time, the four sets of centrifugal mechanisms 3 with position alternation rotation uniformly deposit the cells on the four glass slides 306 in turn; Among them, the linear lifting mechanism 4 running on the side wall drives the cell suspension dropwise adding mechanism 6 to uniformly add the cell suspension to the glass slide 306 which has been marked with number; then the linear lifting mechanism 4 running on the other side wall drives the staining mechanism 5 to move downward for cell staining treatment, after staining, the morphology of cervical exfoliated cells can be observed by microscope; It should be noted that the top of the centrifugal tube 307 is provided with an injection hole, the cervical exfoliated cell sample is stored in the internal storage liquid of the oscillation bottle 208, the driving motor 803 is running to drive the driving bevel gear 802 to rotate, the rotating driving bevel gear 802 drives the driving face gear disc 801 connected in mesh to rotate, the rotating driving face gear disc 801 drives the driven face gear disc 807 to rotate; the rotating driven face gear disc 807 drives the transmission spline rod 203 connected by spline to rotate, the rotating transmission spline rod 203 drives the oscillation disc 206 connected by spline through the spline sleeve 205 to rotate, when the rotating oscillation disc 206 passes through the inclined block 204 by using the bottom annular array distributed roller 207, the oscillation disc 206 moves upward, so that the oscillation disc 206 moves up and down while rotating to generate vibration, the vibration force is transmitted to the oscillation bottle 208 to oscillate the collected cervical exfoliated cell sample, the liquid flow shear force generated by oscillation disperses the cells, breaks the physical binding of cell aggregates, ensures that the cells are in a relatively dispersed state when transferred to the centrifugal tube 307, improves the dispersion degree between the cells, and makes the subsequent centrifugal process more uniform; At the same time, the driven face gear disc 807 rotates through the double-headed bevel gear part 804 connected in mesh to drive the second face gear disc 806 connected in mesh to rotate, the rotating second face gear disc 806 drives the four sets of centrifugal mechanisms 3 to alternately change position at the same time through the rotating frame 805, at the same time, the four sets of centrifugal mechanisms 3 rotate around the first face gear disc 202 connected in mesh by using the first bevel gear 3041 to rotate, specifically, the first bevel gear 3041 drives the intermittent transmission wheel 304 to rotate through self-rotation, the rotating intermittent transmission wheel 304 drives the intermittent rotation assembly 302 to rotate intermittently, drives the continuous clamping table 303 to rotate intermittently, and drives the centrifugal tube 307 and the glass slide 306 to rotate to generate centrifugal force; After the oscillation process is completed, the driving motor 803 stops running, the oscillation bottle 208 on the oscillation disc 206 is kept in a stable position, and then the liquid taking mechanism 7 is driven to move downward by the linear lifting mechanism 4 to extend into the inside of the oscillation bottle 208, so as to extract the cervical exfoliative cell sample in the inside of the oscillation bottle 208, and then the liquid taking mechanism 7 is driven to move upward by the linear lifting mechanism 4, and the cervical exfoliative cell sample is transferred to the centrifugal tube 307 by cooperation of the linear lifting mechanism 4 and the liquid taking mechanism 7; Then the driving motor 803 is driven to run, and the centrifugal force generated by the rotation of the centrifugal mechanism 3 makes the cells move to the wall of the centrifugal tube 307 and uniformly deposit on the glass slide 306 to form a single cell layer; the four groups of centrifugal mechanisms 3 are used to uniformly deposit the cells on the four glass slides 306 in turn, so as to avoid the overlapping of the cells and make the overall morphology of the cells be accurately displayed, which is helpful for doctors to better identify the morphology and structure of the cells; The linear lifting mechanism 4 of one group is driven to move downward to uniformly drop the cell suspension on the glass slide 306 which has been marked and numbered, and the linear lifting mechanism 4 of another group is driven to move upward at this time; The linear lifting mechanism 4 of one group is driven to move upward to move away from the centrifugal tube 307 while the rotating frame 805 is continuously rotated to switch the positions of the four groups of centrifugal mechanisms 3, and the linear lifting mechanism 4 of another group is driven to move downward at this time.

[0018] As shown in Figures 8 to 9 The intermittent rotation assembly 302 is composed of a rotating wheel 3021, a linkage spline rod 3022, a first reset spring 3023 and a stop tooth 3024, the linkage spline rod 3022 is fixedly installed at the top of the rotating wheel 3021, the linkage spline rod 3022 extends to the inside of the spline groove 3031 and is movably connected, the first reset spring 3023 is movably sleeved outside the linkage spline rod 3022, the stop tooth 3024 is fixedly installed on one side of the first reset spring 3023, and the stop tooth 3024 is dynamically in contact with the stop block 3011; It needs to be explained that the intermittent transmission wheel 304 dynamically contacts the rotating wheel 3021, when the intermittent transmission wheel 304 rotates to the high position, the intermittent transmission wheel 304 forms an upward contact force on the rotating wheel 3021, so that the rotating wheel 3021 moves up to press the first return spring 3023, and at the same time the rotating wheel 3021 moves up utilizes the blocking tooth 3024 on one side to contact and connect with the stop block 3011, limiting the rotation of the intermittent transmission wheel 304; when the intermittent transmission wheel 304 rotates to the low position, the intermittent transmission wheel 304 removes the upward contact force on the rotating wheel 3021, and the rotating wheel 3021 moves down under the restoring force of the first return spring 3023, and keeps in contact with the intermittent transmission wheel 304, so that the rotating wheel 3021 is rotated by the intermittent transmission wheel 304, and the rotating rotating wheel 3021 drives the mounting table 301 to rotate intermittently through the linkage spline shaft 3022 and the spline groove 3031.

[0019] As shown in Figures 8 to 10 The clamping assembly 305 is composed of a worm wheel 3051, two one-way lead screws 3052, two lead sleeve frames 3053, two clamping seats 3054 and a worm 3055. The two one-way lead screws 3052 are fixedly installed on the two sides of the worm wheel 3051 respectively, the two lead sleeve frames 3053 are sleeved on the outer sides of the two one-way lead screws 3052 respectively, the two clamping seats 3054 are fixedly installed on the top of one side of the two lead sleeve frames 3053 respectively, and the worm 3055 is meshingly connected with the worm wheel 3051, and one end of the worm 3055 is fixedly installed with a shaft rod extending into the inside of the clamping table 303. It needs to be explained that the hand-held shaft rod drives the worm 3055 to rotate, the rotating worm 3055 drives the two one-way lead screws 3052 to rotate synchronously through the meshing connection of the worm wheel 3051, the two one-way lead screws 3052 drive the two lead sleeve frames 3053 to move linearly relative to each other respectively, so that the two clamping seats 3054 move relative to each other to clamp and fix the centrifugal tube 307 and the glass slide 306.

[0020] As shown in Figure 12 The linear lifting mechanism 4 is composed of a mounting frame 401, a bidirectional lead screw 402, a lead sleeve seat 403, a guide rod 404 and a servo motor 405. The bidirectional lead screw 402 is rotatably installed on one side inside the mounting frame 401, the guide rod 404 is fixedly installed on the other side inside the mounting frame 401, the lead sleeve seat 403 is sleeved on the outer sides of the bidirectional lead screw 402 and the guide rod 404, and the front surface of the lead sleeve seat 403 is fixedly installed with a bracket, the output end of the servo motor 405 is fixedly connected with the bottom end of the bidirectional lead screw 402, and the servo motor 405 is fixedly installed on the bottom of the mounting frame 401. It should be noted that the servo motor 405 drives the bidirectional screw rod 402 to rotate, and the rotating bidirectional screw rod 402 drives the sleeve seat 403 to move vertically and reciprocally, so as to drive the dyeing mechanism 5, the cell suspension drop adding mechanism 6 or the liquid taking mechanism 7 to move up and down through the bracket on the front of the sleeve seat 403.

[0021] As shown in Figure 13 , the dyeing mechanism 5 is composed of a storage tank 501 and a first contact injection head 502, the first contact injection head 502 is screw-mounted at the bottom of the storage tank 501, and the first contact injection head 502 is embeddedly installed in the bracket on the front of the sleeve seat 403. It should be noted that when the linear lifting mechanism 4 drives the dyeing mechanism 5 to move downward, the first contact injection head 502 extends into the centrifugal tube 307, and the first contact injection head 502 continues to move downward to form a liquid outlet passage to transport the dyeing agent stored in the storage tank 501 to the surface of the slide glass 306, so as to dye the cells uniformly distributed on the surface of the slide glass 306.

[0022] As shown in Figure 13 , the first contact injection head 502 is composed of a liquid outlet pipe 5021, a conical hole head 5022, a second reset spring 5023 and a catheter 5024, the conical hole head 5022 is movably installed in the inside of the liquid outlet pipe 5021, the catheter 5024 is movably installed at the bottom of the conical hole head 5022, and the second reset spring 5023 is sleeved on the outside of the catheter 5024. It should be noted that the catheter 5024 extends into the centrifugal tube 307 through the injection hole at the top of the centrifugal tube 307, when the catheter 5024 continues to move downward to generate an upward thrust on the catheter 5024 through the injection hole, the catheter 5024 moves upward to compress the second reset spring 5023, at the same time, the upward moving catheter 5024 drives the conical hole head 5022 to move upward, so that the conical hole head 5022 forms a liquid outlet passage with the inner wall of the liquid outlet pipe 5021, the liquid outlet passage transports the dyeing agent in the liquid outlet pipe 5021 to the conical hole head 5022, transports the dyeing agent to the catheter 5024 through the conical hole head 5022, and drops the dyeing agent to the surface of the slide glass 306 through the catheter 5024; when the catheter 5024 moves away from the inside of the centrifugal tube 307, the centrifugal tube 307 stops pressing the second reset spring 5023, and the catheter 5024 and the conical hole head 5022 reset by the reset force of the second reset spring 5023, so as to close the liquid outlet passage formed by the conical hole head 5022 and the inner wall of the liquid outlet pipe 5021, and achieve the purpose of pressing the contact switch to open the liquid outlet passage.

[0023] As shown in Figures 14 to 15 , the liquid taking mechanism 7 is composed of a telescopic rod 701, an electric rod 702 and a second contact injection head 703, the electric rod 702 is fixedly installed in the inside of the telescopic rod 701, and the second contact injection head 703 is embeddedly installed at one end of the telescopic rod 701. Need to explain, the electric rod 702 power operation drive telescopic rod 701 telescopic movement, telescopic telescopic rod 701 drive second contact injection head 703 horizontal linear movement.

[0024] As Figures 4 to 5 The active face gear plate 801 is rotatably installed at the bottom of the mounting plate 102, the driving motor 803 is fixedly installed at the bottom of the mounting plate 102, the driving motor 803 is fixedly connected with the output end of the driving motor 803 through a shaft, and the driving motor 803 is meshingly connected with the active face gear plate 801. Need to explain, the driving motor 803 drives the active bevel gear 802 to rotate, and the rotating active bevel gear 802 drives the meshingly connected active face gear plate 801 to rotate.

[0025] According to the explanation and teaching of the above description, those skilled in the art of the present application can also make changes and modifications to the above embodiments. Therefore, the present application is not limited to the specific embodiments disclosed and described above, and some modifications and changes of the present application should fall within the protection scope of the claims of the present application. In addition, although some specific terms are used in the specification, these terms are only for convenience of explanation and do not constitute any limitation on the present application.

Claims

1. A multifunctional integrated cervical cancer screening device, comprising a detection box (1), an oscillation mechanism (2), four sets of centrifugation mechanisms (3), and a drive mechanism (8), characterized in that, It also includes linear lifting mechanisms (4) that are fixedly installed on the two side walls and the back wall inside the detection box (1). The front of the linear lifting mechanism (4) on the two side walls is fixedly installed with a staining mechanism (5) and a liquid taking mechanism (7). The front of the linear lifting mechanism (4) on the back wall is fixedly installed with a cell suspension dripping mechanism (6). A slide plate (101) is fixedly installed inside the detection box (1). An installation plate (102) is fixedly installed below the slide plate (101). The oscillation mechanism (2) is fixedly installed on the top of the mounting plate (102). The oscillation mechanism (2) consists of a central platform (201), a transmission spline rod (203), a spline sleeve (205), and an oscillation disk (206). The oscillation disk (206) has through holes in its internal annular array, and the through holes provide a insertion position for the oscillation bottle (208). The spline sleeve (205) is fixedly installed on the bottom of the oscillation disk (206). The transmission spline rod (203) is movably installed inside the central platform (201) and extends to the top of the central platform (201). The top of the transmission spline rod (203) is splinedly connected to the oscillation disk (206) through the spline sleeve (205). Rollers (207) are installed in an annular array at the bottom of the oscillation disk (206). A first toothed disc (202) is fixedly installed on the outside of the central platform (201). Inclined blocks (204) are fixedly installed in an annular array at the top of the central platform (201). The drive mechanism (8) is rotatably mounted on the bottom of the mounting plate (102). The drive mechanism (8) consists of a driving gear plate (801), a driving bevel gear (802), a drive motor (803), a double-headed bevel gear (804), a rotating frame (805), a second gear plate (806), and a driven gear plate (807). The driven gear plate (807) is fixedly mounted on the top of the driving gear plate (801) and extends into the interior of the central platform (201). The top of the gear is splined to the bottom of the transmission spline rod (203); the rotating frame (805) is movably sleeved on the outside of the center platform (201), and the second face gear plate (806) is fixedly installed on the top of the rotating frame (805); the double-headed bevel gear (804) is rotatably installed on one side of the center platform (201) and extends into the interior of the center platform (201); one end of the double-headed bevel gear (804) is meshed with the driven face gear plate (807), and the other end of the double-headed bevel gear (804) is meshed with the second face gear plate (806); The four sets of centrifugal mechanisms (3) are arranged in a ring array on the top of the rotating frame (805). Each centrifugal mechanism (3) consists of a mounting platform (301), an intermittent rotation assembly (302), a clamping platform (303), an intermittent transmission wheel (304), and a clamping assembly (305). A stop block (3011) is fixedly installed on the inner wall of the mounting platform (301). The intermittent transmission wheel (304) is rotatably installed on one side inside the mounting platform (301), and a first bevel gear (3041) extending out of the mounting platform (301) is fixedly installed on one side of the intermittent transmission wheel (304) via a shaft. The first bevel gear (3041) and the first... The gear plate (202) is engaged, the clamping stage (303) is rotatably mounted on the top of the mounting stage (301), and the bottom of the clamping stage (303) is fixedly mounted with a spline groove (3031) extending into the mounting stage (301). The clamping stage (303) is splinedly connected to the intermittent rotating component (302) through the spline groove (3031). The clamping component (305) is mounted inside the clamping stage (303) through a bearing. The top of the clamping stage (303) is clamped and mounted with a glass slide (306) and a centrifuge tube (307) through the clamping component (305), and the centrifuge tube (307) is located on the top surface of the glass slide (306). The oscillation mechanism (2) is driven by the drive mechanism (8), and two sets of linear lifting mechanisms (4) are driven to operate. The oscillation mechanism (2) drives four sets of centrifugal mechanisms (3) to alternately change positions and rotate. The collected cervical exfoliated cell samples are shaken using the operating oscillation mechanism (2) to release the cells. The liquid collection mechanism (7) is then moved up and down by the linear lifting mechanism (4) to transfer the sample inside the shaking bottle (208) in the oscillation mechanism (2) to the centrifuge tube (307) in the centrifugation mechanism (3). The centrifugal force generated by the self-rotating centrifugation mechanism (3) causes the cells to move toward the wall of the centrifuge tube (307) and be evenly deposited on the glass slide (306) to form a monolayer of cells. At the same time, the four sets of centrifugation mechanisms (3) with alternating positions are used to evenly deposit the cells onto the four glass slides (306) in sequence. Among them, a set of linear lifting mechanisms (4) running on the side wall drives the cell suspension dripping mechanism (6) to evenly drip the cell suspension onto the labeled slide (306); then another set of linear lifting mechanisms (4) running on the side wall drives the staining mechanism (5) to move down for cell staining. After staining is completed, the morphology of the exfoliated cervical cells can be observed using a microscope.

2. The multifunctional integrated cervical cancer screening device according to claim 1, characterized in that: The intermittent rotation assembly (302) consists of a rotating wheel (3021), a linkage spline rod (3022), a first return spring (3023), and a stop tooth (3024). The linkage spline rod (3022) is fixedly installed on the top of the rotating wheel (3021). The linkage spline rod (3022) extends into the spline groove (3031) and is movably connected. The first return spring (3023) is movably sleeved on the outside of the linkage spline rod (3022). The stop tooth (3024) is fixedly installed on one side of the first return spring (3023), and the stop tooth (3024) is dynamically abutting against the stop block (3011).

3. The multifunctional integrated cervical cancer screening device according to claim 1, characterized in that: The clamping assembly (305) consists of a worm gear (3051), two one-way lead screws (3052), two thread sleeves (3053), two clamping seats (3054), and a worm (3055). The two one-way lead screws (3052) are respectively fixedly installed on both sides of the worm gear (3051). The two thread sleeves (3053) are respectively sleeved on the outside of the two one-way lead screws (3052). The two clamping seats (3054) are respectively fixedly installed on the top of one side of the two thread sleeves (3053). The worm (3055) is meshed with the worm gear (3051), and one end of the worm (3055) is fixedly installed with a shaft extending out of the clamping table (303).

4. The multifunctional integrated cervical cancer screening device according to claim 1, characterized in that: The linear lifting mechanism (4) consists of a mounting frame (401), a bidirectional lead screw (402), a lead sleeve seat (403), a guide rod (404), and a servo motor (405). The bidirectional lead screw (402) is rotatably mounted on one side inside the mounting frame (401), and the guide rod (404) is fixedly mounted on the other side inside the mounting frame (401). The lead sleeve seat (403) is sleeved on the outside of the bidirectional lead screw (402) and the guide rod (404), and a bracket is fixedly mounted on the front of the lead sleeve seat (403). The output end of the servo motor (405) is fixedly connected to the bottom end of the bidirectional lead screw (402), and the servo motor (405) is fixedly mounted on the bottom of the mounting frame (401).

5. The multifunctional integrated cervical cancer screening device according to claim 4, characterized in that: The dyeing mechanism (5) consists of a storage tank (501) and a first contact injection head (502). The first contact injection head (502) is threadedly installed at the bottom of the storage tank (501) and is embedded in a bracket installed on the front of the wire sleeve seat (403).

6. The multifunctional integrated cervical cancer screening device according to claim 5, characterized in that: The first contact injection head (502) consists of a lower liquid tube (5021), a tapered orifice head (5022), a second return spring (5023), and a conduit (5024). The tapered orifice head (5022) is movably installed inside the lower liquid tube (5021), and the conduit (5024) is movably installed at the bottom of the tapered orifice head (5022). The second return spring (5023) is sleeved on the outside of the conduit (5024).

7. The multifunctional integrated cervical cancer screening device according to claim 1, characterized in that: The liquid dispensing mechanism (7) consists of a telescopic rod (701), an electric rod (702), and a second contact injection head (703). The electric rod (702) is fixedly installed inside the telescopic rod (701), and the second contact injection head (703) is embedded in one end of the telescopic rod (701).

8. The multifunctional integrated cervical cancer screening device according to claim 1, characterized in that: The active face gear disk (801) is rotatably mounted on the bottom of the mounting plate (102), the drive motor (803) is fixedly mounted on the bottom of the mounting plate (102), the active bevel gear (802) is fixedly connected to the output end of the drive motor (803) through a shaft, and the active bevel gear (802) meshes with the active face gear disk (801).

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