Tumor electric field treatment system, tumor treatment equipment and method

Abstract

The invention provides a tumor electric field treatment system, tumor treatment equipment and a tumor treatment method. The system comprises an electrode plate and a controller, wherein the electrode plate comprises a substrate, a plurality of electrode units and a plurality of temperature detection units; the substrate is provided with a plurality of grounding wires and a plurality of dual-purpose signal wires; the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups on a circuit, the grounding ends of the temperature detection units in each column group are jointly connected to the same path of grounding wire, and the temperature detection units in each row group are connected in series to the same path of dual-purpose signal wire; the dual-purpose signal line is suitable for accessing an alternating electric signal to transmit the alternating electric signal to the corresponding electrode unit or accessing a direct current electric signal to transmit a temperature detection signal corresponding to one or more combinations of the temperature detection units; the controller controls each ground and each dual-purpose signal line to apply an alternating electric signal to the target electrode unit. As such, the plurality of electrode units are zoned controlled using fewer conductive traces.

Description

[0001] This application is a divisional application of the applicant's patent application No. 202411498027.8 filed on October 25, 2024, entitled "Tumor Electric Field Therapy System, Electrode Sheet, Tumor Therapy Device and Method". Technical Field

[0002] This application relates to tumor electric field therapy technology, and more particularly to tumor electric field therapy systems, tumor treatment equipment and methods. Background Technology

[0003] Tumor electric field therapy is a treatment that uses low-intensity, medium-to-high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis in mitotic cells, thereby achieving the therapeutic effect on tumors.

[0004] Compared to traditional cancer treatments, tumor electric field (TEF) therapy has an innovative mechanism of action. Certain physiological characteristics of tumor cells, such as their geometry and high-frequency mitosis, make them susceptible to TEF. TEF therapy disrupts the normal aggregation of tubulin by applying directional forces to intracellular polar particles (such as macromolecules and organelles). These processes can lead to physical damage to the cell membrane and apoptosis. During the telophase of mitosis, the morphology of the cleavage groove leads to an uneven distribution of the electric field around it. Under the influence of TEF, the electric field strength at the cleavage groove is significantly enhanced, causing charged substances in the cell to migrate towards the cleavage groove, interfering with or even destroying cell structure formation, ultimately leading to cell division failure and apoptosis.

[0005] In related technologies, tumor electric field therapy systems use an electric field application device to transmit alternating electrical signals for tumor electric field therapy to electrode pads. These pads then apply an alternating electric field to the patient's tumor site for tumor electric field therapy. When the tumor therapeutic electric field is applied to the patient's body, heat accumulates at the application site, causing a corresponding increase in temperature. Therefore, it is necessary to monitor the temperature at the application site. If the temperature becomes too high, the electric field intensity needs to be adjusted promptly to reduce the risk of burns to the patient's skin.

[0006] Tumor electric field therapy systems include at least one pair of electrode pads, each containing multiple electrode units. Even when the same alternating electrical signal is applied to each electrode unit, the heat generated on each unit will vary depending on its location. This means the temperature of each electrode unit across the entire electrode pad will not be completely uniform. Consequently, some electrode units may exceed a preset temperature while others remain at a normal temperature. To improve the effectiveness of tumor electric field therapy, individual control of overheating electrode units is necessary. However, for electrode pads in related technologies, individual control of electrode units requires a conductive trace for each electrode unit within the electrode pad's substrate. This increases the number of conductive traces within the substrate, making the electrode pad less flexible, and also thickens the cables electrically connected to the electrode pad, increasing its overall weight and hindering proper electrode application. Summary of the Invention

[0007] This application aims to at least partially address one of the technical problems in the related art. Therefore, the first objective of this application is to propose a tumor electric field therapy system that can control multiple electrode units in sections using fewer conductive traces, which not only improves the efficacy of tumor electric field therapy but also facilitates electrode application.

[0008] The second objective of this application is to propose a tumor treatment device.

[0009] The third objective of this application is to provide a method for detecting the temperature of an electrode sheet.

[0010] The fourth objective of this application is to propose a method for determining the quality of electrode sheets.

[0011] The fifth objective of this application is to propose a method for identifying electrode type.

[0012] The sixth objective of this application is to provide a computer-readable storage medium.

[0013] The seventh objective of this application is to provide an adapter for tumor electric field therapy.

[0014] The eighth objective of this application is to provide an electric field generator for tumor electric field therapy.

[0015] To achieve the above objectives, a first aspect of this application provides a tumor electric field therapy system, comprising: an electrode sheet, including a substrate on which multiple grounding lines and multiple dual-purpose signal lines are arranged, multiple electrode units capable of applying alternating electrical signals, and multiple temperature detection units respectively corresponding to the multiple electrode units; each temperature detection unit is used to detect the temperature at the corresponding electrode unit and has a grounding terminal and a signal terminal; wherein, the multiple temperature detection units are configured in the circuit as at least two row groups and at least two column groups; the grounding terminals of each temperature detection unit located in the same column group are connected to the same grounding line, and the grounding terminals of each temperature detection unit located in different column groups are respectively connected in parallel through different grounding lines. Each temperature detection unit located in the same row group is connected in series to the same dual-purpose signal line, and the signal terminals of each temperature detection unit located in different row groups are connected in parallel through different dual-purpose signal lines; each dual-purpose signal line is adapted to receive an alternating current signal to transmit an alternating current signal to each electrode unit in the corresponding row group or to receive a direct current signal to transmit one or more combinations of temperature detection signals from each temperature detection unit in the corresponding row group; and a controller is configured to: (1) determine the row group in which the target electrode unit is located, wherein the target electrode unit is the electrode unit to which an alternating current signal needs to be applied; and (2) combine the control of each grounding wire of the electrode sheet with each dual-purpose signal line to transmit an alternating current signal to the target electrode unit.

[0016] According to the embodiments of the tumor electric field therapy system of this application, the electrode pads divide multiple electrode units into multiple row groups and multiple column groups. The grounding terminals of the temperature detection units corresponding to each electrode unit in each column group are connected to the same grounding line. The temperature detection units corresponding to each electrode unit in each row group are connected in series to the same dual-purpose signal line. Each dual-purpose signal line is adapted to receive an alternating current signal to transmit the alternating current signal to each electrode unit in the corresponding row group, or to receive a direct current signal to transmit one or more combinations of temperature detection signals from each temperature detection unit in the corresponding row group. Thus, temperature sampling and alternating current signal transmission can be achieved through the dual-purpose signal line. This not only avoids adding new AC signal lines but also eliminates the need for existing AC signal lines. Therefore, multiple electrode units can be controlled in sections using fewer conductive traces, which not only improves the effect of tumor electric field therapy but also facilitates electrode pad application.

[0017] To achieve the above objectives, a second aspect of this application provides a tumor treatment device, including the aforementioned tumor electric field therapy system.

[0018] To achieve the above objectives, a third aspect of this application provides an electrode temperature detection method, applied to the aforementioned tumor electric field therapy system, wherein the method includes: switching each of the dual-purpose signal lines to transmit DC signals; sequentially and time-divisionally turning on each of the grounding lines to collect temperature detection signals from one or more combinations of temperature detection units in the corresponding row group row by row; and determining the temperature detection signal of each electrode unit based on the collected temperature detection signals.

[0019] To achieve the above objectives, a fourth aspect of this application provides a method for determining the quality of an electrode sheet, characterized in that it is applied to the aforementioned tumor electric field therapy system or the aforementioned tumor treatment device, the method comprising: determining the temperature detection signal of each electrode unit in the electrode sheet by performing the aforementioned electrode sheet temperature detection method; and determining whether the electrode sheet is qualified based on the temperature detection signal.

[0020] To achieve the above objectives, a fifth aspect of this application provides an electrode type identification method, applied to the aforementioned tumor electric field therapy system or the aforementioned tumor treatment device. The method includes: determining the temperature detection signal of each electrode unit in the electrode sheet by performing the aforementioned electrode sheet temperature detection method; and identifying the type of the electrode sheet based on the temperature detection signal.

[0021] To achieve the above objectives, a sixth aspect of this application provides a computer-readable storage medium having a computer program stored thereon. When executed by a processor, the computer program implements the aforementioned electrode temperature detection method; or the aforementioned electrode anomaly detection method; or the aforementioned electrode type identification method.

[0022] To achieve the above objectives, a seventh aspect of this application provides an adapter for tumor electric field therapy, including a first memory and a controller. The first memory stores a computer program, which, when executed by the controller, implements the aforementioned electrode temperature detection method; or the aforementioned electrode abnormality detection method; or the aforementioned electrode type identification method.

[0023] To achieve the above objectives, an eighth aspect of this application provides an electric field generator for tumor electric field therapy, including a second memory and a controller. The second memory stores a computer program, which, when executed by the controller, implements the aforementioned electrode temperature detection method; or the aforementioned electrode abnormality detection method; or the aforementioned electrode type identification method.

[0024] The above description is only an overview of the technical solution of this application. In order to better understand the technical means of this application and to implement it in accordance with the contents of the specification, and to make the above and other objects, features and advantages of this application more obvious and understandable, the following are specific embodiments of this application. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of a tumor electric field therapy system according to an embodiment of this application;

[0026] Figure 2 for Figure 1 The diagram shows the structure of the electrode pads in the tumor electric field therapy system.

[0027] Figure 3 for Figure 1 The diagram shows the circuit connection between an electrode plate and an adapter in a tumor electric field therapy system.

[0028] Figure 4 for Figure 1 The diagram shows the structure of the electrode unit of the tumor electric field therapy system.

[0029] Figure 5 for Figure 1 The diagram shows the circuit connection between an electrode plate, an adapter, and an electric field generator in the tumor electric field therapy system.

[0030] Figure 6 for Figure 1 A schematic block diagram of the internal structure of the adapter of the tumor electric field therapy system is shown.

[0031] Figure 7 for Figure 1 A schematic block diagram of the internal structure of the electric field generator in the tumor electric field therapy system is shown.

[0032] Figure 8 This is a schematic flowchart of an electrode temperature detection method according to an embodiment of this application;

[0033] Figure 9 This is a flowchart illustrating an electrode sheet anomaly detection method according to an embodiment of this application;

[0034] Figure 10 This is a schematic flowchart of a control method for a tumor electric field therapy system according to an embodiment of this application;

[0035] Figure 11 This is a flowchart illustrating an embodiment of the electrode type identification method of this application;

[0036] Figure 12 This is a schematic flowchart of a signal control method for tumor electric field therapy according to an embodiment of this application;

[0037] Figure 13 This is a schematic flowchart of an electrode temperature detection method according to another embodiment of this application;

[0038] Figure 14 This is a flowchart illustrating a method for applying alternating electrical signals for tumor electric field therapy according to another embodiment of this application.

[0039] Figure 15 This is a schematic flowchart of an embodiment of the alternating current signal application method based on a temperature detection signal according to this application;

[0040] Figure 16 This is a flowchart illustrating another embodiment of the alternating current signal application method based on a temperature detection signal.

[0041] Figure 17 This is a schematic diagram of a tumor electric field therapy system according to another embodiment of this application;

[0042] Figure 18 This is a schematic diagram of a tumor electric field therapy system according to another embodiment of this application;

[0043] Figure 19 for Figure 18 The diagram shows the circuit connection between an electrode plate and an adapter in a tumor electric field therapy system.

[0044] Figure 20 This is a schematic diagram of a tumor electric field therapy system according to another embodiment of this application;

[0045] Figure 21 This is a schematic diagram of a tumor electric field therapy system according to another embodiment of this application;

[0046] Figure 22 A schematic diagram of the circuit connection between an electrode plate and an adapter in a tumor electric field therapy system according to another embodiment of this application;

[0047] Figure 23 This is a schematic diagram of the circuit connection between an electrode and an adapter in a tumor electric field therapy system according to another embodiment of this application;

[0048] Figure 24 This is a schematic diagram of a tumor electric field therapy system according to another embodiment of this application;

[0049] Figure 25 for Figure 24 The diagram shows the circuit connection between an electrode plate and an adapter in a tumor electric field therapy system.

[0050] Figure 26 This is a schematic diagram of the circuit connection between an electrode and an adapter in a tumor electric field therapy system according to another embodiment of this application;

[0051] Figure 27 This is a schematic diagram of a tumor electric field therapy system according to another embodiment of this application;

[0052] Figure 28 This is a schematic diagram of the circuit connection between an electrode, an adapter, and an electric field generator in a tumor electric field therapy system according to another embodiment of this application.

[0053] Figure 29 for Figure 27 The diagram shows the structure of the electrode unit of the tumor electric field therapy system.

[0054] Figure 30 for Figure 28 A schematic block diagram of the internal structure of the adapter of the tumor electric field therapy system is shown.

[0055] Figure 31 for Figure 28 A schematic block diagram of the internal structure of the electric field generator in the tumor electric field therapy system is shown.

[0056] Figure 32 This is a flowchart illustrating a control method for a tumor electric field therapy system according to another embodiment of this application.

[0057] Figure 33 This is a schematic flowchart of a signal control method for tumor electric field therapy according to another embodiment of this application.

[0058] Explanation of reference numerals in the attached figures:

[0059] Tumor electric field therapy system 100, 100A~100H or 100', electrode pads 13, 13A~13H or 13', first cable 15 or 15', adapter 20, 20A~20B, 20E~20H or 20', second cable 25 or 25', electric field generator 30 or 30', substrate 31 or 31', electrode unit 33, 33A~33H or 33', temperature detection unit 35 or 35', grounding terminal Sub-terminal 35-1 or 35-1', signal terminal 35-2 or 35-2', temperature sensor 34 or 34', ground terminal 34-1 or 34-1', signal terminal 34-2 or 34-2', diode 36 or 36', anode 36-1 or 36-1', cathode 36-2 or 36-2', second power module 32 or 32', second controller 37 or 37', second communication unit 38 or 38', AC signal generator 3 9 or 39', power supply switch 40 or 40', first controller 51 or 51', ADC unit 52 or 52', voltage divider resistor 53 or 53', control switches 54, 54B, 54E~54H or 54', first control switches 54-1, 54-1B, 54-1E~54-1H or 54-1', second control switches 54-2, 54-2B, 54-2E~54-2H or 54-2', third control... Switches 54-3, 54-3B, 54-3E~54-3H or 54-3'; fourth control switches 54-4, 54-4B, 54-4E~54-4H or 54-4'; fifth control switches 54-5, 54-5B, 54-5E~54-5H or 54-5'; bidirectional switching switches 55, 55B, 55E~55H or 55'; first bidirectional switching switches 55-1, 55-1B, 55-1E~55-1H or 55-1'; second bidirectional switching switches 55-2, 55-2B, 55-2E~55-2H or 55-2'; third bidirectional switching switches 55-3, 55-3B, 55-3E~55-3H or 55-3'; fourth bidirectional switching switches 55-4, 55-4B, 55-4E. ~55-4H or 55-4', First communication unit 56 or 56', Alternating power line 57 or 57', First power module 58 or 58', Grounding wires 18, 18B, 18E~18H or 18', First grounding wires 18-1, 18-1B, 18-1E~18-1H or 18-1', Second grounding wires 18-2, 18-2B, 18-2E~18-2H or 18-2', Third grounding wires 18-3, 18-3B, 18-3E~18-3H or 18-3', Fourth grounding wires 18-4, 18-4B, 18-4E~18-4G or 18-4', Fifth grounding wires 18-5, 18-5B or 18-5', Dual-purpose signal lines 19, 19B, 19E~19H or 19'.The first dual-use signal cable is 19-1, 19-1B, 19-1E~19-1H or 19-1'; the second dual-use signal cable is 19-2, 19-2B, 19-2E~19-2H or 19-2'; the third dual-use signal cable is 19-3, 19-3B, 19-3E~19-3H or 19-3'; the fourth dual-use signal cable is 19-4, 19-4E~19-4F or 19-4'; the first connector is 60 or 60'; the first plug is 61; the first socket is 62; the second connector is 70 or 70'; the second plug is 71 or 71'; the second socket is 72 or 72'. Detailed Implementation

[0060] The embodiments of the technical solution of this application will now be described in detail with reference to the accompanying drawings. These embodiments are only used to more clearly illustrate the technical solution of this application and are therefore merely examples, and should not be used to limit the scope of protection of this application.

[0061] Example 1:

[0062] Figure 1 The diagram shown is a schematic representation of a tumor electric field therapy system 100 according to an embodiment of this application. Figure 1 As shown, the tumor electric field therapy system 100 includes: at least one pair of electrode pads 13, an adapter 20 connected to the at least one pair of electrode pads 13, and an electric field generator 30 connected to the adapter 20. The at least one pair of electrode pads 13 can be disposed in pairs on the patient's body surface, such as... Figure 1 The device comprises four electrode pads 13, with each pair of electrode pads 13 positioned on the patient's body surface. An electric field generator 30 supplies power to at least one pair of electrode pads 13, generating an alternating electric field between the at least one pair of electrode pads 13 for tumor treatment. An adapter 20 is electrically connected between the at least one pair of electrode pads 13 and the electric field generator 30, for transmitting the alternating electrical signal generated by the electric field generator 30 to the at least one pair of electrode pads 13. In other words, the electric field generator 30 generates an alternating electrical signal, which is transmitted to each electrode pad 13 via the adapter 20, thereby generating an alternating electric field between the same pair of electrode pads 13 for tumor treatment, thus applying the alternating electric field to the patient's tumor site for tumor therapy.

[0063] like Figure 1As shown, in this embodiment, there are four electrode pads 13, each electrode pad 13 including the same number of electrode units 33, each electrode unit 33 being electrically connected to the adapter 20, and each electrode pad 13 having 20 electrode units 33. In other embodiments, the tumor electric field therapy system 100 may have more or fewer electrode pads 13; in other embodiments, each pair of electrode pads 13 has the same number of electrode units 33, and different pairs of electrode pads 13 may have different numbers of electrode units 33; in other embodiments, the number of electrode units 33 on each electrode pad 13 may be 9, 13, etc.

[0064] In this embodiment, as Figure 1 As shown, from the spatial structure of the electrode sheet 13, the connection between two electrode units 33 can be called a connecting strip (unlabeled). The spacing between the electrode units 33 can be adjusted through the connecting strip (unlabeled). If an electrode unit 33 is connected to another electrode unit 33 only through one connecting strip (unlabeled), then that electrode unit 33 is an electrode unit 33 with a free end, for example... Figure 1Each electrode pad 13 shown has nine electrode units 33 with free ends. The space surrounding the electrode units 33 with free ends is an open space, meaning that the electrode units 33 with free ends have a certain degree of freedom and can move freely within the open space. For example, the connecting strip (not labeled) can stretch or bend to a certain extent, allowing the electrode units 33 to move in various directions. The reason why some electrode units 33 are set to be in the form of free ends in this embodiment is that after the electrode pad is applied to the human body, the electric field of each electrode unit 33 is inconsistent due to the skin folds and corresponding impedance changes, resulting in inconsistent temperatures among the electrode units 33. Moreover, the electrode units 33 located on the periphery of the electrode pad 13 heat up faster. Therefore, when some electrode units 33 in the electrode pad 13 are in the form of free ends, the heat dissipation space of the peripheral electrode units 33 can be increased by adjusting the electrode units 33 with free ends, thereby accelerating heat dissipation. In addition, the application position of the electrode units 33 with free ends on the human body can be adjusted to flexibly apply the electrode units 33 with free ends to the human body according to actual needs. Specifically, in this embodiment, the electrode sheet 13 has a total of 20 electrode units 33 arranged in a four-row, six-column array. The first and fourth rows each have four electrode units 33, and the second and third rows each have six electrode units 33. The four electrode units 33 in each of the first and fourth rows are located in the second to fifth columns, respectively, and the six electrode units 33 in each of the second and third rows are located in the first to sixth columns, respectively. The electrode sheet 13 is provided with several connecting strips (unlabeled) connecting two adjacent electrode units 33 and a bridging part (unlabeled) connecting to the first cable 15. The bridging part (unlabeled) connects two adjacent electrode units 33 located in the third row and third column and the fourth row and third column. The 20 electrode units 33 can be divided into a left part including the three columns on the left and a right part including the three columns on the right. The left part and the right part are connected only by the bridging part (unlabeled). That is, along the row upwards, there is no connecting strip (unlabeled) between the electrode unit 33 located in the third column and the adjacent electrode unit 33 located in the fourth column, but they form an open space. And along the column upwards, only the two adjacent electrode units 33 in the third and fifth columns are connected by connecting strips (unlabeled). The two adjacent electrode units 33 in the other four columns are not provided with connecting strips.

[0065] Figure 3 for Figure 1 The diagram shows the circuit connection between the electrode 13 and the adapter 20 in the tumor electric field therapy system 100. Figure 4 A schematic diagram of the electrode unit 33 is shown. It is worth noting that: Figure 3 The arrangement of electrode units 33 shown is to more clearly illustrate the electrical connection between an electrode piece 13 and the adapter 20. Figure 3The arrangement of electrode units 33 shown does not represent the spatial arrangement of electrode units 33. Figure 3 The diagram illustrates a bidirectional switch 55 in the adapter 20 where terminal 1 is on and terminal 2 is off to obtain the temperature detection signal from the temperature detection unit 35 of the corresponding electrode unit 33 in the electrode plate 13. In another example, when an alternating electrical signal needs to be applied to the electrode unit 33 in the corresponding electrode plate 13, terminal 1 of the bidirectional switch 55 is controlled to be off and terminal 2 to be on. That is, each bidirectional switch 55 has an alternating electrical signal transmission point (i.e., terminal 2 of the bidirectional switch 55) for transmitting alternating electrical signals and a temperature sampling point (i.e., terminal 1 of the bidirectional switch 55) for acquiring temperature detection signals. Combined with... Figure 1 , Figure 3 as well as Figure 4 The electrode sheet 13 includes: a substrate 31, a plurality of electrode units 33 electrically connected to the substrate 31 at intervals, a plurality of temperature detection units 35, and a first cable 15 electrically connected to the substrate 31. The substrate 31 may be a flexible circuit board. The substrate 31 is embedded with multiple conductive traces, including multiple ground lines 18 and multiple dual-purpose signal lines 19. The first cable 15 has multi-core wires (not shown), each of which is electrically connected to the multiple ground lines 18 and the multiple dual-purpose signal lines 19 of the substrate 31 in a one-to-one correspondence. In this embodiment, the total number of ground lines 18 and dual-purpose signal lines 19 embedded in the substrate 31 does not exceed 9, therefore the number of wires in the first cable 15 does not exceed 9.

[0066] Multiple electrode units 33 are configured into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13 has 20 electrode units 33, which are arranged in the order of 1 to 20 in the circuit connection, divided into four row groups and five column groups, that is, the 20 electrode units 33 are arranged in four rows and five columns in the circuit connection. Each electrode unit 33 is provided with a corresponding temperature detection unit 35, and each temperature detection unit 35 has a signal terminal 35-2 and a ground terminal 35-1. The electrode units 33 and the temperature detection units 35 are both soldered to the substrate 31, and the signal terminal 35-2 of the electrode unit 33 is shorted to the corresponding temperature detection unit 35. Since the multiple temperature detection units 35 are arranged in a one-to-one correspondence with the multiple electrode units 33, the multiple temperature detection units 35 are also arranged in four rows and five columns in the circuit connection. It should be noted that the arrangement shown here is to more clearly illustrate the electrical connection between electrode 13 and adapter 20, and does not represent the spatial arrangement of electrode unit 33. Its spatial structure may be as follows: Figure 2The structure shown is roughly array-like, but it can also be other structures, such as petal-shaped or scattering-shaped, and can be regular or irregular. Electrode unit 33 is configured to apply alternating electrical signals to the patient's tumor site. Temperature detection unit 35 is configured to detect the temperature of the patient's body surface that is in contact with electrode pad 13, i.e., the temperature at the corresponding electrode unit 33, and output a temperature detection signal to adapter 20. In this embodiment, the multi-purpose signal lines 19 of substrate 31 are respectively arranged in a one-to-one correspondence with multiple rows of electrode units 33, and are configured to transmit the alternating electrical signals generated by electric field generator 30 to each electrode unit 33 in the corresponding row group. That is, electrode units 33 located in the same row group are all short-circuited through the same multi-purpose signal line 19 of substrate 31, and electrode units 33 located in different row groups are connected in parallel through different multi-purpose signal lines 19 of substrate 31. The multi-purpose signal lines 19 of substrate 31 are electrically connected to the first cable 15, and then electrically connected to the electric field generator 30 via adapter 20. Furthermore, the dual-purpose signal line 19 of the substrate 31 receives the alternating electrical signal generated by the electric field generator 30 through the first cable 15 and the adapter 20.

[0067] Multiple grounding lines 18 are respectively configured to correspond one-to-one with multiple columns of electrode units 33, and are used to sequentially short-circuit and ground each temperature detection unit 35 in each column. That is, the grounding terminals 35-1 of multiple temperature detection units 35 located in the same column are all short-circuited through the same grounding line 18 of the substrate 31, and the grounding terminals 35-1 of temperature detection units 35 located in different columns are connected in parallel through different grounding lines 18 of the substrate 31. During the temperature detection period, only one of the multiple grounding lines 18 is conducting at any given time, and the rest are disconnected. The two ends of each temperature detection unit 35 are a signal terminal 35-2 and a grounding terminal 35-1, respectively. Multiple temperature detection units 35 located in the same row group are connected in series. The signal terminal 35-2 of one temperature detection unit 35 located at the end of each row group is connected to the DC power supply VCC through a series-connected bidirectional switching switch and a voltage divider resistor. The ground terminals 35-1 of the corresponding temperature detection units 35 in each column group are connected together, and then connected to the control switch 54 through the corresponding ground wire in the multi-path grounding line 18, and then connected to the grounding pin GND. The tumor electric field therapy system 100 configures the switching timing of the bidirectional switching switch 55 and the control switch 54 so that the temperature detection signals detected by one or more corresponding combinations of all temperature detection units 35 of the electrode sheet 13 are sampled respectively.

[0068] like Figure 3As shown, all temperature detection units 35 located in the same row group are connected in series to a single line (such as one of the dual-purpose signal lines 19-1, 19-2, 19-3, and 19-4) and connected to the DC power supply VCC. The grounding terminal 35-1 of all temperature detection units 35 located in the same row group is connected to the grounding pin GND via five grounding wires (such as grounding wires 18-1, 18-2, 18-3, 18-4, and 18-5). The grounding terminal 35-1 of all temperature detection units 35 located in the same column group is connected to the same grounding wire (such as one of the grounding wires 18-1, 18-2, 18-3, 18-4, and 18-5). Each temperature detection unit 35, arranged in a series configuration, has a bidirectional switch (such as bidirectional switch 55-1, 55-2, 55-3 or 55-4) and a voltage divider resistor (such as voltage divider resistor R1, R2, R3 or R4) connected in series at the DC power supply VCC terminal. The voltage divider resistors (such as voltage divider resistor R1, R2, R3 or R4) are all closer to the DC power supply VCC terminal than the bidirectional switch 55 (such as bidirectional switch 55-1, 55-2, 55-3 or 55-4). Each grounding wire 18 is connected in series with a control switch 54 (such as control switch 54-1, 54-2, 54-3, 54-4 or 54-5).

[0069] In this embodiment, with a temperature detection unit 35 configured in each electrode unit 33 for temperature detection, the above-described circuit design reduces the number of wires in the first cable 15, preventing the cable from becoming thicker and harder, thus increasing the difficulty of cable fixation; simultaneously, it avoids the increased number of wires in the first cable 15 affecting the adhesion between the electrode sheet 13 and the corresponding body surface of the patient's tumor site. The substrate 31 has a total of 9 embedded grounding wires 18 and dual-purpose signal lines 19. Specifically, in this embodiment, the substrate 31 has 5 embedded grounding wires 18 and 4 embedded dual-purpose signal lines 19. The number of grounding wires 18 is related to the number of column groups N of the electrode unit 33, and is greater than or equal to the number of column groups, where N is a positive integer. The number of dual-purpose signal lines 19 is related to the number of row groups M of the electrode unit 33, and is greater than or equal to the number of row groups, where M is a positive integer. The number of lines L embedded in the substrate 31 of the electrode sheet 13 is equal to the sum of the number of grounding wires 18 and the number of dual-purpose signal lines 19. In this embodiment, the number of grounding wires 18 is equal to the number of column groups N of electrode unit 33; the number of dual-purpose signal lines 19 is equal to the number of row groups M of electrode unit 33.

[0070] Multiple electrode units 33 are arranged in a roughly two-dimensional array on the substrate 31 at intervals. For example... Figure 2As shown, the electrode sheet 13 in this embodiment includes 20 electrode units 33, arranged in a four-row, six-column array. The first and fourth rows each contain four electrode units 33, and the second and third rows each contain six electrode units 33. The four electrode units 33 in each of the first and fourth rows are located in columns two through five, respectively. The six electrode units 33 in each of the second and third rows are located in columns one through six, respectively. Region 1 is defined as the second and third columns of the first row, and the five electrode units 33 in the first, second, and third columns of the second row. Region 2 is defined as the first, second, and third columns of the third row, and the five electrode units 33 in the second and third columns of the fourth row. Region 3 is defined as the fourth, fifth, and sixth columns of the third row, and the five electrode units 33 in the fourth and fifth columns of the fourth row. Region 4 is defined as the fourth, fifth, and sixth columns of the third row, and the five electrode units 33 in the fourth and fifth columns of the fourth row. Each region (1-4) corresponds to a row group. In other embodiments, the 20 electrode units 33 may also be arranged in other ways, and the 20 electrode units 33 may also be used to divide the regions in other ways. Of course, in other embodiments, the electrode sheet 13 may also have other numbers of electrode units 33. In summary, the implementation of this application is not limited by the number and arrangement of the electrode units 33 of the electrode sheet 13.

[0071] Each electrode unit 33 can be subjected to an alternating electrical signal, thereby enabling the paired electrode sheets 13 to apply an alternating electric field to the tumor site of the patient. Optionally, the electrode unit 33 is a dielectric element, such as a ceramic sheet, or a polymer dielectric layer made of polymer materials. Each temperature detection unit 35 is provided corresponding to one electrode unit 33 to detect the temperature at the corresponding electrode unit 33. Each temperature detection unit 35 can be located at any position of the corresponding electrode unit 33, such as... Figure 3 and Figure 4As shown, in this embodiment, each electrode unit 33 is provided with a through hole 331, which is suitable for installing a temperature detection unit 35. For example, each electrode unit 33 has a through hole 331 in the middle, and a corresponding temperature detection unit 35 is housed in the through hole 331 of each electrode unit 33. Each temperature detection unit 35 has a ground terminal 35-1 and a signal terminal 35-2. Each temperature detection unit 35 includes a temperature sensor 34. The tumor electric field therapy system 100 also includes a plurality of diodes 36. The temperature sensor 34 has a signal terminal 34-2 and a ground terminal 34-1. The diodes 36 have an anode 36-1 and a cathode 36-2. The anode 36-1 of each diode 36 is connected to the ground terminal 35-1 of the corresponding temperature detection unit 35. After the cathodes 36-2 of the corresponding diodes 36 in each row are connected together, they are connected to the ground pin GND through a corresponding control switch 54. Specifically, the anode 36-1 of diode 36 is connected to the ground terminal 34-1 of temperature sensor 34, and the cathode 36-2 of diode 36 is connected to the ground pin GND through a corresponding control switch 54. The ground terminal 34-1 of temperature sensor 34 serves as the ground terminal 35-1 of temperature detection unit 35, and the signal terminal 34-2 of temperature sensor 34 serves as the signal terminal 35-2 of temperature detection unit 35. Temperature sensor 34 can be a thermistor or other temperature sensor. Each temperature sensor 34 corresponds to a diode 36, which is connected in series with the corresponding temperature sensor 34. This diode prevents reverse current flow to prevent detection signals from other electrode units 33 from affecting the temperature sensor 34.

[0072] like Figure 3As shown, the electrode plate 13 in this embodiment includes five grounding wires 18, each grounding wire 18 being used to ground the grounding terminals 35-1 of the temperature detection units 35 in the same row. The five grounding wires 18 of the electrode plate 13 are the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, the fourth grounding wire 18-4, and the fifth grounding wire 18-5. In the five columns of electrode sheet 13, the first column includes electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16; the second column includes electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17; the third column includes electrode unit 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18; the fourth column includes electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19; and the fifth column includes electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20. Specifically, the first grounding wire 18-1 is used to ground electrode units 33-1, 33-6, 33-11, and 33-16 in the first column group; the second grounding wire 18-2 is used to ground the series-connected electrode units 33-1 and 33-2, 33-6 and 33-7, 33-11 and 33-12, and 33-16 and 33-17; the third grounding wire 18-3 is used to ground the series-connected electrode units 33-1 to 33-3, 33-6 to 33-8, and 33-11 to 33-16. 33-13, the series-connected electrode units 33-16 to 33-18 are grounded; the fourth grounding wire 18-4 is used to ground the series-connected electrode units 33-1 to 33-4, the series-connected electrode units 33-6 to 33-9, the series-connected electrode units 33-11 to 33-14, and the series-connected electrode units 33-16 to 33-19; the fifth grounding wire 18-5 is used to ground the series-connected electrode units 33-1 to 33-5, the series-connected electrode units 33-6 to 33-10, the series-connected electrode units 33-11 to 33-15, and the series-connected electrode units 33-16 to 33-20. It should be noted that these grounding wires 18 can be selectively closed or opened. This can be achieved by connecting each grounding wire 18 in series with a control switch 54. That is, the grounding terminal 35-1 of the temperature detection unit 35 corresponding to each electrode unit 33 in each column is connected to the grounding pin through a control switch 54, which will be described in detail below. Figure 4The aforementioned "grounding the electrode unit 33" means that the grounding terminal 34-1 of the corresponding temperature sensor 34 in each column is connected to the anode 36-1 of the corresponding diode 36, and then connected together through the cathode 36-2 of the corresponding diode 36. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 35-1 of all temperature detection units 35 corresponding to the electrode units 33 in each column through the diode 36.

[0073] like Figure 3As shown, the electrode sheet 13 in this embodiment also includes four dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to all electrode units 33 in the corresponding row group and all temperature detection units 35 connected in series, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting alternating electrical signals. Specifically, the four dual-purpose signal lines 19 of the electrode sheet 13 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. Electrode units 33-1 to 33-5, consisting of five electrode units 33 connected in series, are connected to the first dual-purpose signal line 19-1. The temperature detection units 35 corresponding to each of the five electrode units 33 are also connected in series to the first dual-purpose signal line 19-1. Electrode units 33-6 to 33-10, consisting of five electrode units 33 connected in series, are connected to the second dual-purpose signal line 19-2. The temperature detection units 35 corresponding to each of the five electrode units 33 are also connected in series to the second dual-purpose signal line 19-2. Five electrode units 33, from electrode unit 33-11 to electrode unit 33-15, are connected in series to the third dual-purpose signal line 19-3. The temperature detection units 35 corresponding to each of the five electrode units 33, from electrode unit 33-11 to electrode unit 33-15, are also connected in series to the third dual-purpose signal line 19-3. Similarly, five electrode units 33, from electrode unit 33-16 to electrode unit 33-20, are connected in series to the fourth dual-purpose signal line 19-4. The temperature detection units 35 corresponding to each of the five electrode units 33, from electrode unit 33-16 to electrode unit 33-20, are also connected in series to the third dual-purpose signal line 19-4. In short, each dual-purpose signal line 19 connects the electrode units 33 in the same row group in series and connects the temperature detection units 35 corresponding to each electrode unit 33 in the same row group in series to the adapter 20. It should be noted that these dual-purpose signal lines 19 can selectively transmit alternating electrical signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switching switch 55 and coordinating with the closing or opening of the grounding wire 18.In other words, the temperature detection units 35 in each row group are connected in series, and the signal terminals 35-2 of each temperature detection unit 35 in each row group are shorted to the corresponding electrode units 33. They are then connected to a switching unit (unlabeled) through a dual-purpose signal line 19. This switching unit (unlabeled) includes multiple bidirectional switching switches 55, which are configured to switch the dual-purpose signal line 19 to either a temperature sampling point (unlabeled) or an alternating power supply line 57. When the dual-purpose signal line 19 is connected to a temperature sampling point (unlabeled), the switching state of the control switch 54 is configured so that the temperature detection signal detected by the corresponding temperature detection unit 35 in each column group is sampled based on the temperature sampling point (unlabeled). When the dual-purpose signal line 19 is connected to the alternating power supply line 57, at least one electrode unit 33 in a row group is subjected to an alternating electrical signal based on the alternating power supply line 57. This will be described in detail below.

[0074] The multi-path grounding line 18 and the multi-path dual-purpose signal line 19 are both conductive traces embedded in the substrate 31. The substrate 31 is electrically connected to the first cable 15. The multi-path grounding line 18 and the multi-path dual-purpose signal line 19 embedded in the substrate 31 are electrically connected to the corresponding wires (not shown) in the first cable 15.

[0075] The tumor electric field therapy system 100 of this embodiment includes at least one pair of electrode pads 13 as described above, an adapter 20 electrically connected to the electrode pads 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode pads 13 and the electric field generator 30. The electric field generator 30 provides alternating electrical signals to multiple electrode units 33 of the electrode pads 13 via the adapter 20 and the dual-purpose signal line 19 of the electrode pads 13, or is used to receive temperature detection signals output by temperature detection units 35 corresponding to multiple electrode units 33. The adapter 20 transmits the alternating electrical signals generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode pads 13, and is also configured to receive temperature detection signals output by the multiple dual-purpose signal lines 19 of the electrode pads 13.

[0076] refer to Figure 3As shown, the adapter 20 includes: a first controller 51, multiple ADC units 52 connected to the first controller 51, multiple voltage-reducing resistors 53 and multiple control switches 54 corresponding to each of the multiple ADC units 52, multiple bidirectional switching switches 55 corresponding to each of the multiple ADC units 52, a first communication unit 56, an alternating power line 57 corresponding to each of the bidirectional switching switches 55, and a first power module 58 connected to the first communication unit 56, the first controller 51, and the multiple ADC units 52. The first power module 58 provides DC power VCC to each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unlabeled), which are electrically connected to multiple grounding lines 18 and multiple dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode plates 13 through the first cables 15 of the corresponding electrode plates 13. The multiple circuit lines (unlabeled) include multiple alternating power supply lines 57 that transmit alternating electrical signals to the corresponding electrode plates 13 and are electrically connected to the multiplexed dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode plate 13; multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multiplexed dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode plates 13 and are used to power each temperature detection unit 35 of the electrode plate 13 or transmit the temperature detection signal of the electrode plate 13; and multiple circuit lines (unlabeled) that are electrically connected one-to-one to the multiple grounding lines 18 in the substrate 31 of the corresponding electrode plates 13. The number L of circuit lines that the adapter 20 is electrically connected to one electrode plate 13 is equal to the sum of the number of rows and columns of the electrode units 33 of the electrode plate 13; the number H of circuit lines that the adapter 20 is electrically connected to X electrode plates 13 is equal to X times the number of circuit lines that it is electrically connected to a single electrode plate 13, that is, H=XL=X×(M+N). The number of groups of control switches 54 and bidirectional switching switches 55 are related to the number of electrode plates 13. The number of groups of control switches 54 and bidirectional switching switches 55 is the same and not less than the number of electrode plates 13. Optionally, the number of groups of control switches 54 and bidirectional switching switches 55 is the same as the number of electrode plates 13. The following detailed description only takes the electrical connection between an electrode plate 13 with 20 electrode units 33 and the adapter 20 as an example.

[0077] Each group of control switches 54 has multiple control switches 54, which are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multiple grounding wires 18 of a corresponding electrode plate 13, and are configured to control the on or off of the multiple grounding wires 18. The circuit lines (unlabeled) that are each electrically connected to the multiple grounding wires 18 of the electrode plate 13 are grounded at the end closest to the control switch 54. The number of control switches 54 in each group of control switches 54 is related to the number of grounding wires 18 on the substrate 31 of the corresponding electrode plate 13; in this embodiment, the two are equal. Figure 3As shown, in this embodiment, the multiple control switches 54 in each group of control switches 54 are respectively the first control switch 54-1, the second control switch 54-2, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5. The multiple control switches 54 in the same group each control the closing or opening of the corresponding grounding wire 18 of the same electrode plate 13. The first control switch 54-1 is used to control the opening or closing of the first grounding wire 18-1 of the corresponding electrode plate 13, and can then cooperate with the corresponding set of bidirectional switching switches 55 to control the energization and de-energization of the temperature detection units 35 corresponding to the four electrode units 33 (electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16) in the first column of the electrode plate 13; the second control switch 54-2 is used to control the opening or closing of the second grounding wire 18-2 of the electrode plate 13, and can then cooperate with the corresponding set of bidirectional switching switches 55 to control multiple electrode units 33 in the first and second columns of the electrode plate 13 (the multiple electrode units can be: electrode unit 33-1 and electrode unit 33-2, electrode unit 33-6 and electrode unit 33-16 respectively). -7. The temperature detection units 35 corresponding to electrode units 33-11, 33-12, 33-16, and 33-17 are energized and de-energized; the third control switch 54-3 is used to control the closing or opening of the third grounding wire 18-3 of the electrode plate 13, and can cooperate with the corresponding group of bidirectional switching switches 55 to control the energization and de-energization of the temperature detection units 35 corresponding to multiple electrode units 33 (multiple electrode units can be: electrode units 33-1 to 33-3, electrode units 33-6 to 33-8, electrode units 33-11 to 33-13, and electrode units 33-16 to 33-18) in the first, second, and third columns of the electrode plate 13; the fourth control switch 54-4 and the fifth control switch 54-5 are similar. The above control switches 54 can be mechanical switches, such as relays. The control switches 54 can also be electronic switches, and each control switch 54 can be opened and closed by the first controller 51.

[0078] In this embodiment, all sets of control switches 54 are electronic switches. The first controller 51 is communicatively connected to the multiple sets of control switches 54, and is used to sequentially and cyclically control the opening and closing states of multiple control switches 54 in each set, thereby sequentially and individually activating each of the multiple grounding wires 18 of the corresponding electrode pad 13 and coordinating with the switching of the corresponding bidirectional switching switch 55 to collect the patient's body surface temperature detected by all temperature detection units 35 on the electrode pad 13. The number of each set of control switches 54 is not less than the number of grounding wires 18 on the substrate 31 of the corresponding electrode pad 13. In this embodiment, the number of each set of control switches 54 is the same as the number of grounding wires 18 on the corresponding electrode pad 13.

[0079] Each group of bidirectional switching switches 55 is provided with multiple bidirectional switching switches 55. The multiple bidirectional switching switches 55 in each group are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) that correspond one-to-one with the multi-purpose signal lines 19 of the corresponding electrode plate 13. The number of bidirectional switching switches 55 in each group of bidirectional switching switches 55 is related to the number of dual-purpose signal lines 19 on the substrate 31 of the corresponding electrode plate 13, which is greater than or equal to the number of dual-purpose signal lines 19 on the substrate 31 of the corresponding electrode plate 13. In this embodiment, the two are equal. Each bidirectional switch 55 has two ends labeled 1 and 2. The ends of multiple bidirectional switches 55 in the same group are electrically connected to the corresponding detection channels of the multiple detection channels of the corresponding group of ADC units 52 through temperature sampling points (unlabeled). The ends of each bidirectional switch 55 in the same group are electrically connected to the same AC power line 57 and are configured to control the multiplex signal line 19 to connect to the corresponding AC power line 57 to transmit AC electrical signals or to connect to the corresponding detection channel of the corresponding group of ADC units 52 to receive the temperature detection signal output by the temperature detection unit 35.

[0080] like Figure 3As shown, taking the electrical connection of one electrode plate 13 with the adapter 20 as an example, in this embodiment with 20 electrode units 33, the multiple bidirectional switching switches 55 in each group of bidirectional switching switches 55 are respectively the first bidirectional switching switch 55-1, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3, and the fourth bidirectional switching switch 55-4. The multiple bidirectional switching switches 55 in the same group control the switching of a corresponding dual-purpose signal line 19 in the multi-channel dual-purpose signal line 19 of the same electrode plate 13 between transmitting alternating electrical signals and transmitting temperature detection signals. Specifically, the first bidirectional switching switch 55-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode pad 13 between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each electrode unit 33 from electrode unit 33-1 to electrode unit 33-5 in the first row of the electrode pad 13 and the conduction of the signal terminal 35-2 of each temperature detection unit 35 corresponding to electrode unit 33-1 to electrode unit 33-5 in the first row of the electrode pad 13. It also cooperates with the corresponding control switches 54-1, 54-2, 54-3, 54-4, and 54-5 to ensure that the first row of electrode units 33-1 to electrode unit 33-5 transmits alternating electrical signals to the patient or that the temperature detection signals detected by one or more combinations of the temperature detection units 35 corresponding to these electrode units 33 are sampled and output to the corresponding ADC unit 52. The second bidirectional switching switch 55-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode pad 13 between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each electrode unit 33 of the electrode unit 33-6 to electrode unit 33-10 in the second row of the electrode pad 13 and the conduction of the signal terminal 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-6 to electrode unit 33-10 in the second row of the electrode group, and cooperating with the corresponding control switches 54-1, 54-2, 54-3, 54-4, and 54-5 so that the second row of electrode units 33-6 to electrode unit 33-10 transmits alternating electrical signals to the patient or causes the temperature detection signals detected by one or more combinations of the temperature detection units 35 corresponding to these electrode units 33 to be sampled and output to the corresponding ADC unit 52.The third bidirectional switching switch 55-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode pad 13 between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each electrode unit 33 from electrode unit 33-11 to electrode unit 33-15 in the third row of the electrode pad 13 and the conduction of the signal terminals 35-2 of each temperature detection unit corresponding to electrode unit 33-11 to electrode unit 33-15 in the third row of the electrode pad 13, and cooperating with the corresponding control switches 54-1, 54-2, 54-3, 54-4, and 54-5, so that the third row of electrode units 33-11 to electrode unit 33-15 transmits alternating electrical signals to the patient or causes the temperature detection signals detected by one or more combinations of the temperature detection units 35 corresponding to these electrode units 33 to be sampled and output to the corresponding ADC unit 52; The four bidirectional switching switches 55-4 are used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode pad 13 between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of each electrode unit 33 in the fourth row of electrode units 33-16 to 33-20 and the conduction of the signal terminals 35-2 of each temperature detection unit 35 corresponding to the electrode units 33-16 to 33-20 in the fourth row of electrode units 33-16 to 33-20. It also works in conjunction with the corresponding control switches 54-1, 54-2, 54-3, 54-4, and 54-5 to enable the fourth row of electrode units 33-16 to 33-20 to transmit alternating electrical signals to the patient or to sample and output the temperature detection signals detected by one or more combinations of the temperature detection units 35 corresponding to these electrode units 33 to the corresponding ADC unit 52. When both ends of each bidirectional switch 55 are on and one end is off, alternating electrical signals can be transmitted to each electrode unit 33 of the corresponding electrode plate 13. When each bidirectional switch 55 in each group is sequentially and time-divisionally on one end and off the other two ends, and all the other bidirectional switches 55 are on and off the other two ends, it can cooperate with each control switch 54 in the corresponding group of control switches 54 to transmit the temperature detection signals collected by the temperature detection units 35 of each electrode unit 33 on the electrode plate 13 in a time-division manner. The bidirectional switch 55 can be a mechanical switch, such as a relay. The bidirectional switch 55 can also be an electronic switch, and each bidirectional switch 55 can be switched by the first controller 51.

[0081] In this embodiment, all of the multiple sets of bidirectional switching switches 55 are electronic switches. The first controller 51 is communicatively connected to the multiple sets of bidirectional switching switches 55 and is used to control the switching of multiple bidirectional switching switches 55 in each set between their respective terminals 1 and 2, and to cooperate with the closing or opening of the corresponding control switch 54, so as to continuously monitor the temperature of the patient's body surface detected by all temperature detection units 35 on the electrode pad 13 or transmit alternating electrical signals to the patient.

[0082] In this embodiment, each ADC unit 52 is electrically connected to one end of one of the multiple bidirectional switching switches 55 in the corresponding group through multiple circuit lines (unlabeled) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multi-channel dual-purpose signal line 19 of the corresponding electrode 13, and convert the temperature detection signal from an analog signal to a digital temperature signal. Figure 3 As shown, each ADC unit 52 contains four detection channels A, B, C, and D, namely the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. Each detection channel A, B, C, and D is used to connect to one of the multi-channel dual-purpose signal lines 19 and a corresponding temperature sampling point (unlabeled) through a corresponding bidirectional switch 55. Specifically, the first detection channel A is connected to the first dual-purpose signal line 19-1 through terminal 1 of the first bidirectional switch 55-1, the second detection channel B is connected to the second dual-purpose signal line 19-2 through terminal 1 of the second bidirectional switch 55-2, the third detection channel C is connected to the third dual-purpose signal line 19-3 through terminal 1 of the third bidirectional switch 55-3, and the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through terminal 1 of the fourth bidirectional switch 55-4. Each detection channel A, B, C, and D is used to receive the temperature detection signal collected by the temperature detection unit 35 corresponding to the electrode unit 33 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, and D is connected to a first power supply module 58 via a corresponding voltage divider resistor 53 in the adapter 20 to provide detection voltage to the detection channel A, B, C, and D. The first power supply module 58 provides DC power.

[0083] In this embodiment, the first communication unit 56 is configured to acquire digital temperature signals output by multiple sets of ADC units 52 and send the digital temperature signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage of the alternating electrical signal provided to the multiple electrode units 33 of the electrode sheet 13 according to the received digital temperature signals. For example, when any of the received digital temperature signals exceeds a preset threshold, it indicates that the temperature detected by the temperature detection unit 35 corresponding to at least one electrode unit 33 in the electrode sheet 13 exceeds the preset temperature threshold (e.g., 41°C, 42°C, etc.). At this time, the voltage of the alternating electrical signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode unit 33 of the electrode sheet 13 from becoming too hot when the alternating electrical signal is applied, causing low-temperature burns to the patient's skin. The aforementioned preset temperature threshold and preset threshold can be determined according to human safety thresholds. The first communication unit 56 is controlled by the first controller 51 and serially transmits the digital temperature signals converted by multiple sets of ADC units 52. In this embodiment, the preset temperature threshold can be a value within the range of 36°C-45°C.

[0084] refer to Figure 5 and Figure 6 In this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30 and is configured to supply power to the first controller 51, multiple ADC units 52, and the first communication unit 56 of the adapter 20. Each electrode 13 is connected to the adapter 20 via a first connector 60, which is adapted to connect the corresponding electrode 13 to the adapter 20. Figure 1 As shown, the first connector 60 includes a first plug 61 located at the end of the first cable 15 away from the electrode plate 13 and a first socket 62 located on the adapter 20. The first plug 61 and the first socket 62 are press-type spring connectors, that is, the first connector 60 connects the adapter 20 and the electrode plate 13 by means of a connector. Each first cable 15 has 4 wires that are electrically connected to the corresponding bidirectional switch 55 in the corresponding set of bidirectional switch 55 and 5 wires that are electrically connected to the corresponding control switch 54 in the corresponding set of control switches 54. That is, each first connector 60 is electrically connected to the corresponding set of bidirectional switch 55 and the corresponding set of control switches 54 of the adapter 20 through 9 wires, and is connected to the electric field generator 30 through a corresponding alternating power line 57 of the adapter 20.

[0085] A second connector 70 is provided between the adapter 20 and the electric field generator 30, and the second connector 70 is adapted to connect the electric field generator 30 to the adapter 20. For example... Figure 1As shown, the adapter 20 also includes a second cable 25 connected to the second connector 70. The second connector 70 includes a second plug 71 located at the end of the second cable 25 away from the first controller 51 and a second socket 72 located on the electric field generator 30. The second plug 71 and the second socket 72 are push-button spring connectors, that is, the second connector 70 connects the adapter 20 to the electric field generator 30 using a connector method. Each first connector 60, such as X1, Y1, X2, and Y2, is connected to the second connector 70 via a corresponding alternating power line 57. The first connectors 60, such as X1, Y1, X2, and Y2, are also connected to a corresponding set of control switches 54 and a corresponding set of ADC units 52, respectively. Each first connector 60 is connected to the second connector 70 and the corresponding set of ADC units 52 via a corresponding set of bidirectional switching switches 55. The second cable 25 has eight wires, including four wires 1 to 4 that are electrically connected to the corresponding alternating power lines 57 and used for transmitting alternating electrical signals, one wire 5 that is electrically connected to the data receiving line RX of the first communication unit 56, one wire 6 that is electrically connected to the data transmitting line TX of the first communication unit 56, one wire 7 that is electrically connected to the VCC power line of the first power module 58, and one wire 8 that is electrically connected to the GND line of the first power module 58. The second connector 70 is connected to the first communication unit 56 via the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58, and the GND pin of the second connector 70 is connected to the GND line of the first power module 58 and grounded. The VCC pin of the second connector 70 is also connected to the corresponding group of voltage-reducing resistors 53 and the corresponding group of ADC units 52 via the VCC power line of the first power module 58.

[0086] refer to Figure 5 and Figure 7The electric field generator 30 includes a second power supply module 32, a second controller 37, an AC signal generator 39, a second communication unit 38, and a set of power switches 40. The VCC pin of the second connector 70 is also electrically connected to the VCC power line of the second power supply module 32, and the GND pin of the second connector 70 is grounded through the GND line of the second power supply module 32. The second power supply module 32 is also connected to and supplies power to the second controller 37 and the AC signal generator 39, respectively. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 through its data receiving line RX and to the wire 6 of the second connector 70 through its data transmitting line TX, thereby enabling information exchange between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39, and a set of power switches 40. The second controller 37 is configured to control the opening and closing of each power switch 40 in the set of power switches 40 and adjust the relevant parameters of the alternating electrical signal applied by the AC signal generator 39 according to the relevant digital temperature signal received from the adapter 20 by the second communication unit 38. The AC signal generator 39 is electrically connected to the conductors 1 to 4 of the second connector 70 for transmitting alternating electrical signals through the set of power switches 40. The set of power switches 40 includes multiple power switches 40, and the multiple power switches 40 are arranged one-to-one with multiple electrode plates 13. Each power switch 40 is electrically connected to a corresponding conductor 1, 2, 3, 4 in the second connector 70 for transmitting alternating electrical signals through an AC power line 41-1, 41-2, 41-3, 41-4, and is also electrically connected to the corresponding electrode plate 13 through the corresponding conductors 1, 2, 3, 4 of the second connector 70, so as to transmit an alternating electrical signal to each electrode plate 13. The AC signal generator 39 is electrically connected to the group of power supply switches 40 via multiple AC power lines 41. Specifically, the number of power supply switches 40 of the electric field generator 30 is related to the number of electrode plates 13. In this embodiment, the number of power supply switches 40 is equal to the number of electrode plates 13, and both are four. The power supply switches 40 include a first power supply switch 40-1, a second power supply switch 40-2, a third power supply switch 40-3, and a fourth power supply switch 40-4, which are electrically connected to the wires 1 to 4 of the second connector 70 respectively.One end of the first power supply switch 40-1 is electrically connected to the AC signal generator 39 via the AC power line (unlabeled) of the electric field generator 30. The other end is electrically connected to the corresponding conductor 1 for transmitting alternating electrical signals in the second connector 70 via an AC power line 41-1, and is also electrically connected to the AC power line 57 at port X1 of the adapter 20 via the conductor 1 of the second connector 70. The AC power line 57 at port X1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at port X1 of the adapter 20 is electrically connected to the corresponding electrode plate 13, thereby controlling whether the AC signal generator 39 supplies alternating electrical signals to the electrode plate 13 electrically connected to port X1 of the adapter 20. The second power supply switch 40-2 is electrically connected at one end to the AC signal generator 39 via the AC power line (unlabeled) of the electric field generator 30, and at the other end via an AC power line 41-2 to the corresponding conductor 2 for transmitting alternating electrical signals in the second connector 70. The conductor 2 of the second connector 70 is then electrically connected to the alternating power line 57 at port Y1 of the adapter 20. The alternating power line 57 at port Y1 of the adapter 20 is electrically connected to the first connector 60. The first connector 60 at port Y1 of the adapter 20 is electrically connected to the corresponding electrode 13, thereby controlling whether the AC signal generator 39 supplies alternating electrical signals to the electrode 13 electrically connected to port Y1 of the adapter 20. The third power supply switch 40-3 is electrically connected at one end to the AC signal generator 39 via the AC power line (unlabeled) of the electric field generator 30, and at the other end via an AC power line 41-3 to the corresponding conductor 3 transmitting alternating electrical signals in the second connector 70. The conductor 3 of the second connector 70 is then electrically connected to the alternating power line 57 at port X2 of the adapter 20. The alternating power line 57 at port X2 of the adapter 20 is electrically connected to the first connector 60. The first connector 60 at port X2 of the adapter 20 is electrically connected to the corresponding electrode 13, thereby controlling whether the AC signal generator 39 supplies alternating electrical signals to the electrode 13 electrically connected to port X2 of the adapter 20. The fourth power supply switch 40-4 is electrically connected at one end to the AC signal generator 39 via the AC power line (unlabeled) of the electric field generator 30, and at the other end via an AC power line 41-4 to the corresponding conductor 4 in the second connector 70 that transmits alternating electrical signals. It is also electrically connected via the conductor 4 of the second connector 70 to the alternating power line 57 at port Y2 of the adapter 20. The alternating power line 57 at port Y2 of the adapter 20 is electrically connected to the first connector 60. The first connector 60 at port Y2 of the adapter 20 is electrically connected to the corresponding electrode 13, so as to control whether the AC signal generator 39 transmits alternating electrical signals to the electrode 13 electrically connected to port Y1 of the adapter 20.

[0087] The following will refer to Figures 3 to 5The working principle of the tumor electric field therapy system 100 in this embodiment is described in detail.

[0088] Specifically, when it is necessary to detect the temperature at each electrode unit 33 of an electrode plate 13, the second controller 37 of the electric field generator 30 controls the corresponding power supply switch 40 to disconnect the alternating electrical signal applied to the electrode plate 13; simultaneously, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 configures the switching and switching sequence of each control switch 54 and each bidirectional switching switch 55 in a set of control switches 54 electrically connected to the electrode plate 13. At this time, the temperature detection signals of one or more temperature detection units 35 corresponding to the electrode units 33 in the corresponding row group can be collected by multiple detection channels A, B, C, and D of a set of ADC units 52 corresponding to the electrode plate 13. The temperature detection signals can be characterized by resistance values. Only one of the five control switches 54 in the set of control switches 54 corresponding to the electrode plate 13 can be turned on at any given time, while the other four are turned off. At any given time, only one of the bidirectional switching switches 55 corresponding to the electrode 13 can be turned on at one end and turned off at the other end. The remaining bidirectional switching switches 55 are turned on at both ends and turned off at the other end. This allows the dual-purpose signal line 19 of the electrode 13 to be electrically connected to one of the corresponding detection channels A, B, C, and D of the corresponding ADC unit 52. With this configuration, the ADC unit 52 can acquire temperature detection signals from one or more combinations of temperature detection units 35 corresponding to the electrode units 33 in the row group corresponding to the turned-on bidirectional switching switches 55.

[0089] Specifically, the electric field generator 30 disconnects the alternating electrical signal applied to the electrode plate 13. Terminal 1 of the first bidirectional switch 55-1 is turned on and terminal 2 is turned off. Terminals 2 of the remaining bidirectional switches 55 (second bidirectional switch 55-2, third bidirectional switch 55-3, and fourth bidirectional switch 55-4) are all turned on and terminal 1 is all turned off. Simultaneously, the first control switch 54-1 is closed, and the second control switch 54-2, third control switch 54-3, fourth control switch 54-4, and fifth control switch 54-5 are all turned off. The temperature detection unit 35 corresponding to the electrode unit 33-1 of the first row group is energized, and the temperature detection units 35 corresponding to the remaining electrode units 33 are de-energized. This group of ADCs... In unit 52, the signal terminal 35-2 of the temperature detection unit 35 corresponding to electrode unit 33-1 is shorted on the first detection channel A. Since only the ground terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-1 is grounded, while the ground terminals 35-1 of the remaining electrode units 33 are all disconnected, only the temperature detection unit 35 corresponding to electrode unit 33-1 is effectively working on the first detection channel A of this ADC unit 52. The temperature detection signal (resistance value) collected by the first detection channel A is the temperature detection signal (resistance value) of the temperature detection unit 35 corresponding to electrode unit 33-1.

[0090] The first bidirectional switch 55-1 is turned on at terminal 1 and turned off at terminal 2. The remaining bidirectional switches 55 (the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4) are all turned on at terminal 2 and turned off at terminal 1. Simultaneously, the second control switch 54-2 is closed, and the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 are all turned off. The temperature detection units 35 corresponding to electrode units 33-1 to 33-2 in the first row group are energized, while the temperature detection units 35 corresponding to the remaining electrode units 33 are de-energized. The temperature detection unit 35 corresponding to electrode unit 33-1 is short-circuited on the first detection channel A of the ADC unit 52 in this group. Signal terminal 35-2, ground terminal 35-1 of temperature detection unit 35 corresponding to electrode unit 33-2 is connected to ground, so the temperature detection units 35 corresponding to electrode units 33-1 to 33-2 on the first detection channel A of this ADC unit 52 are effectively operating. The temperature detection signal (resistance value) collected by the first detection channel A is the combined temperature detection signal (resistance value) of the temperature detection units 35 corresponding to electrode units 33-1 to 33-2. Subtracting the temperature detection signal (resistance value) of the aforementioned temperature detection unit 35 corresponding to electrode unit 33-1 from this combined temperature detection signal (resistance value) gives the temperature detection signal (resistance value) of the temperature detection unit 35 corresponding to electrode unit 33-2.

[0091] The first bidirectional switch 55-1 is turned on at terminal 1 and turned off at terminal 2. The remaining bidirectional switches 55 (the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4) are all turned on at terminal 2 and turned off at terminal 1. Simultaneously, the third control switch 54-3 is closed, and the first control switch 54-1, the second control switch 54-2, the fourth control switch 54-4, and the fifth control switch 54-5 are all turned off. The temperature detection units 35 corresponding to electrode units 33-1 to 33-3 in the first row group are energized, while the temperature detection units 35 corresponding to the remaining electrode units 33 are de-energized. The signal terminal 35-2 of the temperature detection unit 35 corresponding to electrode unit 33-1 is short-circuited on the first detection channel A of the ADC unit 52 in this group. The grounding terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-3 is grounded. Therefore, the temperature detection units 35 corresponding to electrode units 33-1 to 33-3 on the first detection channel A of the ADC unit 52 are effectively operating. The temperature detection signal (resistance value) collected by the first detection channel A is the combined temperature detection signal (resistance value) of the temperature detection units 35 corresponding to electrode units 33-1 to 33-3. Subtracting the combined temperature detection signal (resistance value) of the temperature detection units 35 corresponding to electrode units 33-1 to 33-2 from this combined temperature detection signal (resistance value) gives the temperature detection signal (resistance value) of the temperature detection unit 35 corresponding to electrode unit 33-3.

[0092] The first bidirectional switch 55-1 is turned on at terminal 1 and turned off at terminal 2. The remaining bidirectional switches 55 (the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4) are all turned on at terminal 2 and turned off at terminal 1. Simultaneously, the fourth control switch 54-4 is closed, and the first control switch 54-1, the second control switch 54-2, the third control switch 54-3, and the fifth control switch 54-5 are all turned off. The temperature detection units 35 corresponding to electrode units 33-1 to 33-4 in the first row group are energized, while the temperature detection units 35 corresponding to the remaining electrode units 33 are de-energized. The signal terminal 35-2 of the temperature detection unit 35 corresponding to electrode unit 33-1 is short-circuited on the first detection channel A of the ADC unit 52 in this group. The grounding terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-4 is grounded. Therefore, the temperature detection units 35 corresponding to electrode units 33-1 to 33-4 on the first detection channel A of the ADC unit 52 are effectively operating. The temperature detection signal (resistance value) collected by the first detection channel A is the combined temperature detection signal (resistance value) of the temperature detection units 35 corresponding to electrode units 33-1 to 33-4. Subtracting the combined temperature detection signal (resistance value) of the temperature detection units 35 corresponding to electrode units 33-1 to 33-3 from this combined temperature detection signal (resistance value) gives the temperature detection signal (resistance value) of the temperature detection unit 35 corresponding to electrode unit 33-4.

[0093] The first bidirectional switch 55-1 is turned on at terminal 1 and turned off at terminal 2. The remaining bidirectional switches 55 (the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4) are all turned on at terminal 2 and turned off at terminal 1. Simultaneously, the fifth control switch 54-5 is closed, and the first, second, third, and fourth control switches 54-1, 54-2, 54-3, and 54-4 are all turned off. The temperature detection units 35 corresponding to electrode units 33-1 to 33-5 in the first row group are energized, while the temperature detection units 35 corresponding to the remaining electrode units 33 are de-energized. The signal terminal 35-2 of the temperature detection unit 35 corresponding to electrode unit 33-1 is short-circuited on the first detection channel A of the ADC unit 52 in this group. The grounding terminal 35-1 of the temperature detection unit 35 corresponding to electrode unit 33-5 is grounded. Therefore, the temperature detection units 35 corresponding to electrode units 33-1 to 33-5 on the first detection channel A of the ADC unit 52 are effectively operating. The temperature detection signal (resistance value) collected by the first detection channel A is the combined temperature detection signal (resistance value) of the temperature detection units 35 corresponding to electrode units 33-1 to 33-5. Subtracting the combined temperature detection signal (resistance value) of the temperature detection units 35 corresponding to electrode units 33-1 to 33-4 from this combined temperature detection signal (resistance value) gives the temperature detection signal (resistance value) of the temperature detection unit 35 corresponding to electrode unit 33-5.

[0094] Thus, the temperature detection signal (resistance value) of each temperature detection unit 35 corresponding to all electrode units 33 in the first row of the electrode sheet 13 is obtained. By analogy, the temperature detection signal (resistance value) of each temperature detection unit 35 corresponding to each electrode unit 33 in the remaining rows can be obtained.

[0095] Therefore, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can acquire the temperature detection signals of the temperature detection units 35 corresponding to all electrode units 33 of a certain electrode sheet 13 by controlling a set of bidirectional switching switches 55 and a set of control switches 54 that are all electrically connected to a certain electrode sheet 13. That is, the switching unit (unlabeled) is configured to switch the dual-purpose signal line 19 of the corresponding row group to the corresponding temperature sampling point (unlabeled), and the switching state of the control switch 54 of the corresponding column group is configured to obtain the temperature detection signal of a single temperature detection unit 35 or the combined temperature detection signal of multiple temperature detection units 35. Similarly, the temperature detection signals of the temperature detection units 35 of each electrode unit 33 of other electrode sheets 13 can be obtained.

[0096] The first controller 51 or the second controller 37, multiple ADC units 52, and multiple sets of bidirectional switching switches 55 can automatically execute operations through pre-programmed program code. For example, the first controller 51 or the second controller 37 first controls all bidirectional switching switches 55 in the corresponding set to switch to end 1, so that all ends 1 of these bidirectional switching switches 55 are turned on and all ends 2 are turned off, so that each dual-purpose signal line 19 of the corresponding electrode plate 13 is electrically connected to the corresponding set of ADC units 52. Then, it closes the control switch 54-1 in the corresponding set of control switches 54 and opens the remaining control switches 54-2 to 54-5 in the set of control switches 54. During this period, each detection of the ADC unit 52 in the set of ADC units 52... Channels A, B, C, and D acquire the temperature detection signals of each temperature detection unit 35 corresponding to each electrode unit 33 in the first column group of the corresponding electrode sheet 13, convert them into digital temperature signals, and store them in a separately set memory. Then, after a preset interval, the first controller 51 or the second controller 37 closes control switch 54-2 in the group of control switches 54, and opens control switches 54-1, 54-3, 54-4, and 54-5 in the group of control switches 54. During this period, each detection channel A, B, C, and D of the group of ADC units 52 acquires the temperature detection signal of a single temperature detection unit 35 or a combined temperature detection signal of multiple temperature detection units 35. By sequentially turning on each control switch 54 in the group of control switches 54, the temperature detection signals of all temperature detection units 35 on the electrode sheet 13 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature detection units 35 on at least one pair of electrode sheets 13 can be obtained.

[0097] The first controller 51 serially transmits the digital temperature signal obtained by the ADC unit 52 from the temperature detection signals of each temperature detection unit 35 through the first communication unit 56, such as to the electric field generator 30.

[0098] It should be noted that in other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can control a set of bidirectional switching switches 55 and a set of control switches 54 electrically connected to a certain electrode plate 13 to collect temperature detection signals of temperature detection units 35 corresponding to some electrode units 33 of the electrode plate 13 during the same temperature acquisition time period. For example, during the same acquisition time period, only the temperature detection signal of the temperature detection unit 35 corresponding to a single electrode unit 33 in a row group can be sampled. Similarly, during other acquisition time periods, the temperature detection signals of one or more temperature detection units 35 corresponding to electrode units 33 in other rows can be sampled. That is, the switching unit (unlabeled) is configured to switch the dual-purpose signal line 19 corresponding to each row group to the corresponding temperature sampling point (unlabeled), and the switching state of the control switch 54 is configured so that the temperature detection signals detected by one or more temperature detection units 35 in each row group are sampled respectively. It should be noted that in some other embodiments, the temperature detection signals of the temperature detection units 35 corresponding to one or more electrode units 33 in each of the two or three rows can be sampled within the same acquisition time period. The specific details will not be elaborated here.

[0099] Specifically, when it is necessary to apply an alternating electrical signal to each electrode unit 33 of an electrode plate 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each of the multiple bidirectional switching switches 55 electrically connected to the electrode plate 13 to turn on two ends and turn off one end, and controls a power supply switch 40 electrically connected to the electrode plate 13 to turn on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electrical signal to each electrode unit 33 of the electrode plate 13 through the alternating power supply line 57, and the magnitude of the applied alternating electrical signal voltage or current is adjustable. That is, the switching unit (unlabeled) is configured to switch the dual-purpose signal lines 19 corresponding to at least two row groups to be simultaneously connected to the alternating power supply line 57, so that the electrode units 33 of at least two row groups are simultaneously applied with alternating electrical signals based on the alternating power supply line 57.

[0100] It should be noted that in other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a group of bidirectional switching switches 55 electrically connected to a certain electrode plate 13 to apply alternating electrical signals to some electrode units 33 of the electrode plate 13 at the same time period. For example, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the first bidirectional switching switch 55-1 of a group of bidirectional switching switches 55 electrically connected to the electrode plate 13 to have its two ends turned on and its one end turned off, while the remaining bidirectional switching switches 55 have their one end turned on and their two ends turned off. At the same time, all control switches 54 are turned off, and a power supply switch 40 electrically connected to the electrode plate 13 is turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply alternating electrical signals to the first row of electrode units 33-1 to 33-5 located on the electrode plate 13 through the alternating power line 57, and the magnitude of the applied alternating electrical signal voltage or current is adjustable. That is, the switching unit (unlabeled) is configured to switch the dual-purpose signal line 19 corresponding to each row group to the alternating power supply line 57, so that the electrode unit 33 of each row group is simultaneously subjected to an alternating electrical signal based on the alternating power supply line 57. It should be noted that in some other embodiments, alternating electrical signals can also be applied to the electrode units 33 of two or three row groups at the same time period, which will not be described in detail here.

[0101] It should be noted that in this embodiment, the control switch 54, which is electrically connected to each of the multiple grounding lines 18 of the electrode plate 13, and the bidirectional switching switch 55, which is electrically connected to each of the multiple dual-purpose signal lines 19 of the electrode plate 13, are both located in the adapter 20. However, in other embodiments, the control switch 54, which is electrically connected to the grounding line 18, and the bidirectional switching switch 55, which is electrically connected to the dual-purpose signal line 19, may also be located on the electrode plate 13 or in the electric field generator 30, which will not be elaborated further here. In addition, the ADC unit 52 located in the adapter 20 may also be located in the electric field generator 30 and directly controlled by the second controller 37.

[0102] The tumor electric field therapy system 100 of this application can achieve real-time and comprehensive temperature monitoring of all electrode units 33 on the electrode sheet 13 without increasing the weight of the electrode sheet 13 or the number of wire cores in the first cable 15 electrically connected to the electrode sheet 13. Based on the obtained temperature detection signals, it can determine whether the electrode sheet 13 is qualified; or it can determine whether the temperature detection unit 35 of the electrode sheet 13 is faulty or abnormal based on the obtained temperature detection signals, and determine whether the electrode sheet 13 needs to be replaced based on the number of faulty or abnormal temperature detection units 35; or, if the electrode sheet is qualified, it can identify the electrode sheet type based on the obtained temperature detection signals; or, if the electrode sheet is qualified, it can determine whether the electrode units 33 of the electrode sheet 13 are overheated based on the obtained temperature detection signals, and further control the alternating electrical signals applied to the electrode sheet 13 or the corresponding electrode units 33 of the electrode sheet 13, thus avoiding low-temperature burns to the patient's skin during tumor treatment through the electrode sheet 13. Furthermore, the substrate 31 of the electrode sheet 13 of this application is electrically connected to the signal terminal 35-2 of the same electrode unit 33 and its corresponding temperature detection unit 35 via the same dual-purpose signal line 19. This allows for the transmission of both alternating current signals and DC signals for temperature signal acquisition, as well as the acquired temperature detection signals, via the dual-purpose signal line 19. Simultaneously, it significantly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) laid on the substrate, reducing the wiring difficulty of the substrate 31, simplifying the manufacturing process, reducing the weight of the substrate 31, and lowering manufacturing costs. The electrode sheet 13 of this application can also switch between applying alternating current signals for tumor treatment and transmitting DC signals for temperature acquisition and transmitting the acquired temperature detection signals through a combination of a control switch 54 electrically connected to the grounding line 18 and a bidirectional switching switch 55 electrically connected to the dual-purpose signal line 19.

[0103] Specifically, when it is necessary to apply alternating electrical signals to the patient through each electrode unit 33 of an electrode pad 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls all the control switches 54 in a set of control switches 54 corresponding to the electrode pad 13 to be disconnected, and at the same time controls all the bidirectional switching switches 55 in a set of bidirectional switching switches 55 corresponding to the electrode pad 13 to be switched to their respective 2 ends, so that 1 ends of these bidirectional switching switches 55 are all disconnected and 2 ends are all connected, so that each dual-purpose signal line 19 of the electrode pad 13 is electrically connected to an alternating power line 57 corresponding to the electrode pad 13 of the adapter 20, thereby transmitting the alternating electrical signals to each electrode unit 33 of the electrode pad 13.When the temperature detection signals of the temperature detection units 35 corresponding to all electrode units 33 of the detected electrode plate 13 are much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue generating alternating electrical signals with increased voltage or current amplitude, or with constant voltage or current amplitude, and then transmits them to the corresponding counter electrode plate 13 through a corresponding alternating power line 57 of the adapter 20, so that the counter electrode plate 13 continues to be applied with alternating electrical signals; when the temperature detection signals of the temperature detection units 35 corresponding to all electrode units 33 of the detected electrode plate 13 are lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator... The generator 30 can reduce the voltage or current of the alternating signal generated by the AC signal generator 39 through the second controller 37, thereby reducing the voltage or current of the alternating signal applied to the electrode 13; when it is detected that the temperature obtained by converting the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33 of a certain electrode 13 is greater than the preset temperature threshold, the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode 13 to disconnect through the second controller 37, so as to stop applying the alternating signal to the electrode 13; or the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 controls all the bidirectional switching switches 55 in a group electrically connected to the electrode 13 to automatically switch off. When the two ends of the switch are switched to the one end, that is, when all the two ends of a set of bidirectional switches 55 electrically connected to the electrode plate 13 are turned on, the alternating electrical signal applied to the electrode plate 13 is stopped; or, when it is detected that the temperature obtained by converting the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33 of a certain electrode plate 13 is greater than the preset temperature threshold, the second controller 37 of the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode plate 13 to continue to be turned on, and the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 controls the bidirectional switch 55 electrically connected to the electrode unit 33 of the electrode plate 13 to switch from its two ends to its one end. At the same time, the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 simultaneously controls the remaining bidirectional switching switches 55 that are electrically connected to the electrode units 33 in different rows from the electrode units 33 whose temperature obtained from the temperature detection signal of the electrode sheet 13 does not exceed the preset temperature threshold, so as to stop applying alternating electrical signals to all electrode units 33 in the row where the temperature obtained from the temperature detection signal of the electrode sheet 13 exceeds the preset temperature threshold, and continue to apply alternating electrical signals to the remaining rows of electrode units 33 whose temperature obtained from the temperature detection signal of the electrode sheet 13 does not exceed the preset temperature threshold.This enables a tumor electric field therapy system 100 based on an alternating electrical signal application control method using a temperature detection signal.

[0104] This application provides an electrode temperature detection method, applied to the electrode 13 or the tumor electric field therapy system 100 described above, with reference to... Figure 8 As shown, it includes the following steps:

[0105] Step 210: Control the switching unit so that the dual-use signal line 19 corresponding to each row group in the corresponding electrode sheet 13 is sequentially connected to the corresponding temperature sampling point.

[0106] Specifically, the power supply switch 40 of the electric field generator 30 is controlled to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode plate 13. At the same time, each of the bidirectional switching switches 55 electrically connected to each electrode unit 33 of the electrode plate 13 is controlled to sequentially perform the action of one end being turned on and the other end being turned off. The remaining bidirectional switching switches 55 are all turned on at one end and all ends are turned off at the other end, so as to connect the DC electrical signal applied to the signal terminal 35-2 of the temperature detection unit 35 corresponding to each electrode unit 33 in a certain row of the electrode plate 13.

[0107] Furthermore, each bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode plate 13 is sequentially switched from its end connected to the alternating current signal to its end connected to the direct current signal, while the remaining bidirectional switching switches 55 are switched from their end connected to the direct current signal to their end connected to the alternating current signal. That is, each bidirectional switching switch 55 electrically connected to the electrode plate 13 is sequentially switched from its 2nd end to its 1st end, while the remaining bidirectional switching switches 55 are switched from their 1st end to their 2nd end; or, each bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode plate 13 sequentially causes each electrode unit 33 in the row group corresponding to the bidirectional switching switch 55 in the electrode plate 13 to switch from the on state to the off state, and at the same time causes the signal terminal 35-2 of the temperature detection unit 35 corresponding to each electrode unit 33 in the row group corresponding to the bidirectional switching switch 55 in the electrode plate 13 to switch from the off state to the on state.

[0108] Step 220: Control the control switch 54 corresponding to each column group so as to sample the temperature detection signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0109] Specifically, a control switch 54, which is electrically connected to the ground terminal 35-1 of the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode sheet 13, is turned on in a time-sequential manner, and a bidirectional switching switch 55 is used in conjunction with it to obtain the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode sheet 13.

[0110] In some embodiments, when the dual-use signal lines 19 corresponding to each row group are sequentially connected to the corresponding temperature sampling points, the control switch 54 corresponding to each column group is controlled, including: controlling the control switch 54 corresponding to each column group to close sequentially, so as to sample the temperature detection signal of each electrode unit 33 in each row group respectively.

[0111] The electrode temperature detection method of this application can quickly and accurately obtain the temperature of all electrode units of the electrode sheet; and can determine whether the temperature detection units of the electrode sheet are faulty, abnormal, or whether the electrode sheet is qualified and needs to be replaced based on the obtained temperature detection signals of all temperature detection units of the electrode sheet; it can also determine whether each electrode unit of the electrode sheet is overheated based on the obtained temperature detection signals of all temperature detection units of the electrode sheet when all temperature detection units of the electrode sheet are normal, and then control the alternating electrical signal applied to the electrode sheet or each electrode unit of the electrode sheet; it can also identify the electrode sheet type when the temperature detection signals of each temperature detection unit of the electrode sheet are normal.

[0112] The first controller 51 or electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of this application embodiment is provided with a preset threshold, a first preset temperature, a second preset temperature and a preset temperature threshold, wherein the first preset temperature is lower than the second preset temperature and the second preset temperature is lower than the preset temperature threshold.

[0113] Reference Figure 9 As shown, this application also provides a method for detecting abnormal temperature of an electrode sheet, which includes the following steps:

[0114] Step 210: Control the switching unit so that the dual-use signal line 19 corresponding to each row group in the corresponding electrode sheet 13 is sequentially connected to the corresponding temperature sampling point.

[0115] Step 220: Control the control switch 54 corresponding to each column group so as to sample the temperature detection signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0116] Step 230: Determine whether there is any abnormality in electrode plate 13 based on the temperature detection signal.

[0117] In some embodiments, step 230, which determines whether the electrode plate 13 is abnormal based on the temperature detection signal, specifically includes the following steps:

[0118] Step 231: Compare the temperature at each electrode unit 33 in the corresponding electrode sheet 13 with a preset temperature threshold based on the temperature detection signal. Specifically, the temperature obtained by converting the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 can be compared with the preset temperature threshold.

[0119] Step 232: Determine whether the temperature of the electrode sheet 13 is abnormal based on the comparison results. Specifically, determine whether there is any temperature abnormality in each electrode unit 33 within the electrode sheet 13 based on the comparison results.

[0120] The comparison results in step 232 include those that do not exceed a preset temperature threshold and those that exceed a preset temperature threshold. "Does not exceed the preset temperature threshold" includes "far below the preset temperature threshold" and "close to the preset temperature threshold." The preset temperature threshold is 40℃-42℃. Optionally, the preset temperature threshold is 40.5℃-41.5℃. Optionally, the preset temperature threshold is 41℃-41.5℃. Optionally, the preset temperature threshold is 41℃.

[0121] The process of determining whether the temperature of the electrode sheet 13 is abnormal based on the comparison results in step 232 is as follows: if the temperature at any electrode unit 33 in the corresponding electrode sheet 13 exceeds a preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is abnormal. If the temperature at all electrode units 33 in the corresponding electrode sheet 13 does not exceed the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is not abnormal.

[0122] In other embodiments, step 230, which determines whether the electrode plate 13 is abnormal based on the temperature detection signal, specifically includes the following steps:

[0123] Step 233: If it is determined from the temperature detection signal that any electrode unit 33 in the corresponding electrode sheet 13 is abnormal or has a fault, the electrode sheet 13 is deemed unqualified.

[0124] Specifically, based on the temperature detection signals detected by the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13, it is determined whether the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13 are abnormal or faulty; then, based on whether the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13 are abnormal or faulty, it is determined whether the electrode sheet 13 is qualified. Specifically, if the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13 are abnormal or faulty, the electrode sheet 13 is determined to be unqualified; if the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13 are not abnormal or faulty, the electrode sheet 13 is determined to be qualified.

[0125] In some other embodiments, step 230, which involves determining whether the electrode plate 13 is abnormal based on the temperature detection signal, specifically includes the following steps:

[0126] Step 234: If it is determined from the temperature detection signal that there is an abnormal or faulty electrode unit 33 in the corresponding electrode sheet 13, determine the number of abnormal or faulty electrode units 33.

[0127] Step 235: If the number of abnormal or faulty electrode units 33 reaches a preset threshold, it is determined that the electrode sheet 13 needs to be replaced.

[0128] Specifically, based on the temperature detection signals of the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13, it is determined whether there is any abnormality or malfunction in the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13; then, based on whether there is any abnormality or malfunction in the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13, it is determined whether the electrode sheet 13 needs to be replaced.

[0129] For example, if the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or malfunctioning, and the number of abnormal or malfunctioning temperature detection units 35 exceeds a preset threshold, it is determined that the electrode sheet 13 needs to be replaced; if the number of abnormal or malfunctioning temperature detection units 35 in the electrode sheet 13 does not exceed the preset threshold, it is determined that the electrode sheet 13 does not need to be replaced. The preset threshold is 20% of the total number of temperature detection units 35 in the electrode sheet 13.

[0130] Reference Figure 10 As shown, this application also provides a control method for a tumor electric field therapy system, which includes the following steps:

[0131] Step 210: Control the switching unit so that the dual-use signal line 19 corresponding to each row group in the corresponding electrode sheet 13 is sequentially connected to the corresponding temperature sampling point.

[0132] Step 220: Control the control switch 54 corresponding to each column group so as to sample the temperature detection signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0133] Step 240: Control the intensity of the alternating electrical signal applied to the electrode unit 33 according to the temperature detection signal.

[0134] Specifically, when it is determined that the electrode plate 13 does not need to be replaced, the alternating electrical signal applied to each electrode unit 33 in the electrode plate 13 is controlled or adjusted according to the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode plate 13. That is to say, steps 234-235 can be added between steps 240 and 220.

[0135] In some embodiments, controlling the intensity of the alternating electrical signal applied to the electrode unit 33 based on the temperature detection signal in step 240 specifically includes the following steps:

[0136] Step 241: Compare the temperature at each electrode unit 33 in the electrode sheet 13 with the preset temperature threshold based on the temperature detection signal.

[0137] Step 242: Control the strength of the alternating current signal based on the comparison results.

[0138] In some embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242 specifically includes:

[0139] Step 2421: If the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, stop applying alternating electrical signals to the electrode units 33 of the electrode sheet 13. Specifically, stop applying alternating electrical signals to the electrode units 33 of the electrode sheet 13 when the temperature obtained from the temperature detection signals of all the electrode units 33 exceeds the preset temperature threshold. Continue applying alternating electrical signals to each electrode unit 33 of the electrode sheet 13 when the temperature obtained from the temperature detection signals of all the electrode units 33 does not exceed the preset temperature threshold.

[0140] In some embodiments, stopping the application of alternating electrical signals to the electrode units 33 of the electrode sheet 13 in step 2421 specifically includes: stopping the application of alternating electrical signals to all electrode units 33 of the electrode sheet 13; or stopping the application of alternating electrical signals to all electrode units 33 in the row group of electrode units 33 that exceed a preset temperature threshold in the electrode sheet 13.

[0141] Furthermore, while ceasing the application of alternating electrical signals to all electrode units 33 in the row group containing electrode units 33 exceeding a preset temperature threshold, alternating electrical signals continue to be applied to electrode units 33 in other rows of the electrode sheet 13. The intensity of the alternating electrical signals applied to the electrode units 33 in other rows of the electrode sheet 13 is adjustable. For example, all electrode units 33 in the electrode sheet 13 whose temperature obtained from the temperature detection signal conversion does not exceed the preset temperature threshold and are located in a different row from the electrode units 33 whose temperature obtained from the temperature detection signal conversion exceeds the preset temperature threshold, are still subject to alternating electrical signals, and these signals are adjustable.

[0142] In other embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242 specifically includes:

[0143] Step 2422: If the temperature at all electrode units 33 in the electrode sheet 13 does not exceed the preset temperature threshold, and if the temperature at all electrode units 33 in the electrode sheet 13 does not exceed the first preset temperature, then increase the intensity of the alternating electrical signal applied to the electrode units 33 of the electrode sheet 13, wherein the first preset temperature is less than the preset temperature threshold.

[0144] In step 2422, the electric field intensity increases by the same amount for each row group where the alternating electrical signal intensity is increased.

[0145] Step 2423: If the temperature at all electrode units 33 in the electrode sheet 13 does not exceed the preset temperature threshold, and if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the first preset temperature but is less than the second preset temperature, then the alternating electrical signal strength currently applied to the electrode unit 33 of the electrode sheet 13 remains unchanged.

[0146] Step 2424: If the temperature at all electrode units 33 in the electrode sheet 13 does not exceed the preset temperature threshold, and if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the second preset temperature but is less than the preset temperature threshold, then reduce the intensity of the alternating electrical signal applied to the electrode unit 33 of the electrode sheet 13, wherein the second preset temperature is greater than the first preset temperature but less than the preset temperature threshold.

[0147] In step 2424, the electric field intensity of each row group of electrode units 33 that reduces the alternating electric signal intensity decreases by the same amount.

[0148] For example, when the temperature obtained from the temperature detection signal is much lower than a preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 by increasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13, or by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 constant. When the temperature obtained from the temperature detection signal is close to the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 constant, or by decreasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13.

[0149] In some other embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242 specifically includes:

[0150] Step 2425: If the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, determine the number of over-temperature rows.

[0151] Step 2426: If the number of overheated rows exceeds a preset threshold, stop applying alternating electrical signals to all electrode units 33 of the electrode sheet 13.

[0152] Step 2427: If the number of rows with excessive temperature does not exceed the preset threshold, stop applying alternating electrical signals to all electrode units 33 in the row group where the electrode unit 33 with excessive temperature exceeds the preset threshold in the electrode sheet 13.

[0153] Furthermore, while ceasing the application of alternating electrical signals to all electrode units 33 in the row group containing electrode units 33 that exceed a preset temperature threshold in the electrode sheet 13, alternating electrical signals continue to be applied to electrode units 33 in other row groups in the electrode sheet 13. The intensity of the alternating electrical signals applied to the electrode units 33 in other row groups in the electrode sheet 13 is adjustable.

[0154] Step 2428: If the number of overheated rows does not exceed a preset threshold, and the temperature at each electrode unit 33 in the non-overheated rows does not exceed a first preset temperature, then increase the intensity of the alternating electrical signal applied to the electrode unit 33 of the non-overheated rows, wherein the first preset temperature is less than a preset temperature threshold.

[0155] In step 2428, the electric field intensity increases by the same amount for each row group where the alternating electrical signal intensity is increased.

[0156] Step 2429: If the number of overheated rows does not exceed the preset number threshold, and if the temperature at at least one electrode unit 33 in the non-overheated rows exceeds the first preset temperature but is less than the second preset temperature, then the alternating electrical signal strength currently applied to the electrode unit 33 in the non-overheated rows remains unchanged.

[0157] Step 2430: If the number of overheated rows does not exceed a preset threshold, and if at least one electrode unit 33 in the non-overheated rows has a temperature that exceeds a second preset temperature but is less than a preset temperature threshold, then reduce the intensity of the alternating electrical signal applied to the electrode unit 33 in the non-overheated rows, wherein the second preset temperature is greater than the first preset temperature but less than the preset temperature threshold.

[0158] In step 2430, the electric field intensity of each row group whose alternating electrical signal intensity is reduced is reduced by the same amount.

[0159] For example, when the temperature detection signal is much lower than a preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 by increasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13, or by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 constant. When the temperature detection signal is close to the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13 constant, or by decreasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33 of the electrode sheet 13.

[0160] Reference Figure 11 As shown, this application also provides a method for identifying electrode type, which includes the following steps:

[0161] Step 210: Control the switching unit so that the dual-use signal line 19 corresponding to each row group in the corresponding electrode sheet 13 is sequentially connected to the corresponding temperature sampling point.

[0162] Step 220: Control the control switch 54 corresponding to each column group so as to sample the temperature detection signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0163] Step 250: Identify the type of electrode 13 based on the temperature detection signal.

[0164] Specifically, if the electrode sheet 13 is qualified or the temperature detection units 35 of the electrode sheet 13 are not abnormal or have no faults, the type of the electrode sheet 13 is identified based on the temperature detection signals detected by the temperature detection units 35 corresponding to each electrode unit 33 in the electrode sheet 13.

[0165] This application also provides a signal control method for tumor electric field therapy, used in the tumor electric field therapy system 100 or the electrode sheet 13 described above. The method includes: combined control of a control switch 54 and a bidirectional switching switch 55 electrically connected to the electrode sheet 13 to switch each electrode unit 33 of the electrode sheet 13 between applying an alternating electrical signal and acquiring a temperature detection signal.

[0166] Reference Figure 12 As shown, this application also provides a signal control method for tumor electric field therapy, used in the above-mentioned electrode sheet 13, the method comprising:

[0167] Step 310: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the corresponding electrode sheet 13 to apply alternating electrical signals to each electrode unit 33 of the electrode sheet 13 and execute step 320;

[0168] Step 320: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to collect the temperature detection signals of each electrode unit 33 of the electrode plate 13 in a row and execute step 330;

[0169] Step 330: Determine the combined control mode of the control switch 54 and the bidirectional switching switch 55 electrically connected to the electrode 13 based on the collected temperature detection signal and execute step 340;

[0170] Step 340: Control the working state of each electrode unit 33 of the electrode sheet 13 according to the determined combination control method of control switch 54 and bidirectional switching switch 55.

[0171] The operating states of each electrode unit 33 of the electrode sheet 13 in step 340 include at least one of the following: stopping the application of alternating current signals and continuing to acquire temperature detection signals, and stopping the acquisition of temperature detection signals and continuing to apply alternating current signals. Continuing to apply alternating current signals includes continuing to apply alternating current signals by increasing the voltage or current amplitude of the currently applied alternating current signals, or continuing to apply alternating current signals by keeping the voltage or current amplitude of the currently applied alternating current signals unchanged, or continuing to apply alternating current signals by decreasing the voltage or current amplitude of the currently applied alternating current signals.

[0172] The operating state of each electrode unit 33 of the electrode sheet 13 is determined by the temperature detection signal it collects. Each electrode unit 33 of the electrode sheet 13 is divided into different regions, and each electrode unit 33 in each region can be cyclically switched between applying an alternating electrical signal and collecting a temperature detection signal by a combination of control switch 54 and bidirectional switching switch 55.

[0173] This application provides another method for detecting the temperature of electrode pads in a tumor electric field therapy system 100. Please refer to... Figure 13 As shown, the temperature detection method includes:

[0174] Step 510: Disconnect the input of the alternating electrical signal to the electrode 13, perform combined control of multiple control switches 54 and multiple bidirectional switching switches 55, and acquire the temperature detection signal of the temperature detection unit 35 of the electrode 13 corresponding to each combination.

[0175] Step 520: Sample and convert the temperature detection signal detected by each temperature detection unit 35 in the electrode 13 to obtain a digital temperature signal;

[0176] Step 530: The digital temperature signal is transmitted to the electric field generator 30 of the tumor electric field therapy system 100 so that the electric field generator 30 can determine the temperature at the corresponding electrode unit 33 based on the digital temperature signal.

[0177] In step 510, the combined control of multiple control switches 54 and multiple bidirectional switching switches 55 specifically includes:

[0178] Step 511: Control multiple bidirectional switching switches 55 so that the dual-purpose signal lines 19 corresponding to each row group in the corresponding electrode sheet 13 are sequentially connected to the corresponding temperature sampling points; place one bidirectional switching switch 55 at end 1 and the remaining bidirectional switching switches 55 at end 2 to conduct the electrical connection between the signal terminals 35-2 of each temperature detection unit 35 corresponding to each electrode unit 33 in the row group corresponding to the bidirectional switching switch 55 at end 1 and the corresponding ADC unit 52.

[0179] Step 512: Sequentially close one of the multiple control switches 54 individually to collect the temperature detection signals detected by each temperature detection unit 35 corresponding to each electrode unit 33 in the corresponding row group.

[0180] In step 512, closing one of the multiple control switches 54 in sequence and at different times can ground the ADC unit 52 and each temperature detection unit 35 in the corresponding column of the closed control switch 54 in sequence.

[0181] Thus, the temperature detection signals of each temperature detection unit 35 in each row group can be obtained sequentially, and then processed by the adapter 20 or the electric field generator 30 to obtain the temperature of all electrode units 33 on the electrode sheet 13, thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0182] The tumor electric field therapy system 100 of this application embodiment can perform temperature detection on individual electrode units 33. For example, temperature detection can be performed on a single electrode unit 33 located in the first column group. Taking electrode unit 33-1 as an example: the input of the alternating current signal is disconnected, the bidirectional switch 55 corresponding to the row group where the electrode unit 33-1 that needs to be individually measured is located is set to end 1, and the remaining bidirectional switch 55s are set to end 2; at the same time, the control switch 54 corresponding to the column group where the electrode unit 33-1 that needs to be individually measured is located is turned on and grounded, and all the remaining control switches 54 are turned off. Thus, the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-1 that needs to be individually measured can be sampled to obtain the temperature of the electrode unit 33-1. For example, the bidirectional switch 55-1 corresponding to electrode unit 33-1 is set to end 1, and all the remaining bidirectional switches (55-2 to 55-4) are set to end 2; simultaneously, the control switch 54-1 corresponding to electrode unit 33-1 is closed and grounded, and all the remaining control switches (54-2 to 54-5) are opened. Thus, the temperature of electrode unit 33-1 can be detected. Similarly, the other electrode units 33-6, 33-11, and 33-16 in the first column can also be individually temperature-detected. In addition to temperature detection of a single electrode unit 33 located in the first column, the temperature detection signals of other electrode units 33 are combined signals. For example, when the bidirectional switching switch 55-2 corresponding to electrode unit 33-2 is placed at end 1, and the remaining bidirectional switching switches (55-1, 55-3 to 55-4) are all placed at end 2; at the same time, the control switch 54-2 corresponding to electrode unit 33-2 is closed and grounded, and the remaining control switches (54-1, 54-3 to 54-5) are all opened, the temperature detection signal obtained at this time is a combined temperature detection signal of electrode unit 33-1 and electrode unit 33-2. The temperature detection signal of electrode unit 33-2 can be obtained by subtracting the temperature detection signal of electrode unit 33-1 from the combined temperature detection signal.

[0183] This application embodiment also provides another method for applying alternating electrical signals for tumor electric field therapy, applied to the aforementioned tumor electric field therapy system 100. Please refer to... Figure 14 As shown, the method for applying the alternating electrical signal includes:

[0184] Step 610: Determine the region (1-4) in which the electrode unit 33, to which the alternating electrical signal needs to be applied, is located in the electrode sheet 13;

[0185] Step 611: Combine multiple control switches 54 and multiple bidirectional switching switches 55 that are electrically connected to the electrode plate 13 to apply alternating electrical signals.

[0186] In step 611, the combination of multiple control switches 54 and multiple bidirectional switching switches 55 electrically connected to electrode plate 13 specifically refers to:

[0187] Step 612: Disconnect all control switches 54 that are electrically connected to electrode plate 13;

[0188] Step 613: Determine the row group where the electrode units 33 in the areas where the alternating electrical signals need to be applied are located, based on the area where the alternating electrical signals need to be applied.

[0189] Step 614: Determine the bidirectional switching switch 55 that is electrically connected to the electrode unit 33 in the row group where the electrode unit 33 that needs to be applied an alternating signal is located;

[0190] Step 615: Control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to be applied with alternating current signal to connect the electrode unit 33 that needs to be applied with alternating current signal to the alternating power supply line 57 to apply alternating current signal; at the same time, control the remaining bidirectional switching switches 55 to disconnect the electrical connection between each electrode unit 33 in the area where alternating current signal does not need to be applied and the alternating power supply line 57, thereby stopping the application of alternating current signal.

[0191] In step 615, "connecting the electrode unit 33 that needs to be applied with an alternating signal to the alternating power supply line 57 to apply the alternating signal, and disconnecting the electrical connection between the electrode unit 33 in the area where no alternating signal needs to be applied and the alternating power supply line 57 to stop applying the alternating signal" is achieved by placing the bidirectional switching switch 55, which is electrically connected to the electrode unit 33 in the row group corresponding to the area (1-4) in the electrode sheet 13 where the alternating signal needs to be applied, at its 2 end, and placing all the bidirectional switching switches 55, which are electrically connected to the electrode unit 33 in the remaining row groups, at their 1 end.

[0192] The first controller 51 or electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of this application embodiment is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2 and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2 and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0193] This application also provides a method for applying alternating electrical signals based on temperature detection signals, used in the aforementioned tumor electric field therapy system 100. Please refer to... Figure 15 As shown, the application method includes:

[0194] Step 710: Activate the tumor electric field therapy system 100;

[0195] Step 711: Combine the control switch 54 (also called grounding switch) and the bidirectional switching switch 55 that are electrically connected to the corresponding electrode plate 13 to apply alternating electrical signals to each electrode unit 33 of the electrode plate 13;

[0196] Step 712: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to obtain the temperature of each electrode unit 33 of the electrode plate 13;

[0197] Step 713: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 33 with a temperature exceeding the first preset temperature t1, proceed to step 714. If there is an electrode unit 33 with a temperature exceeding the first preset temperature t1, proceed to step 715.

[0198] Step 714: Continue to apply alternating current signals to each electrode unit 33 of electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating current signal and return to step 712;

[0199] Step 715: Determine whether there is an electrode unit 33 with a temperature exceeding the second preset temperature t2; if there is no electrode unit 33 with a temperature exceeding the second preset temperature t2, proceed to step 716; if there is an electrode unit 33 with a temperature exceeding the second preset temperature t2, proceed to step 717.

[0200] Step 716: Continue to apply alternating current signals to each electrode unit 33 of electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and return to step 712;

[0201] Step 717: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, proceed to step 718; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, proceed to step 719.

[0202] Step 718: Continue to apply alternating current signals to all electrode units 33 of electrode sheet 13 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal and return to step 712;

[0203] Step 719: Determine the number of overheated areas and proceed to step 720, wherein the overheated area is the area containing electrode units whose temperature exceeds the preset temperature threshold t0, and the non-overheated area is the area where the temperature of all electrode units does not exceed the preset temperature threshold t0.

[0204] Step 720: Determine whether the number of overheated areas exceeds the preset number threshold. If the number of overheated areas exceeds the preset number threshold, proceed to step 721. If the number of overheated areas does not exceed the preset number threshold, proceed to step 724.

[0205] Step 721: Stop applying alternating electrical signals to each electrode unit 33 of the electrode sheet 13 and proceed to step 722;

[0206] Step 722: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to obtain the temperature of each electrode unit 33 of the electrode plate 13 and execute step 723;

[0207] Step 723: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 33 with a temperature exceeding the first preset temperature t1 on the electrode sheet 13, return to step 711. If there is an electrode unit 33 with a temperature exceeding the first preset temperature t1 on the electrode sheet 13, return to step 722.

[0208] Step 724: Distinguish between overheated and non-overheated regions based on whether there is an electrode unit 33 with a temperature exceeding the preset temperature threshold t0. If the region is an overheated region, proceed to step 725; if the region is a non-overheated region, proceed to step 726.

[0209] Step 725: Stop applying alternating electrical signals to each electrode unit 33 in the over-temperature region and proceed to step 731;

[0210] Step 726: Determine whether the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1, execute step 727. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the first preset temperature t1, execute step 728.

[0211] Step 727: Continue to apply alternating current signals to each electrode unit 33 in the non-over-temperature region of electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating current signal and execute step 731;

[0212] Step 728: Determine whether the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2, proceed to step 729. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the second preset temperature t2, proceed to step 730.

[0213] Step 729: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area of ​​electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and execute step 731;

[0214] Step 730: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area of ​​electrode sheet 13 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal and execute step 731;

[0215] Step 731: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to reacquire the temperature of each electrode unit 33 of the electrode plate 13 and select to execute step 732 or step 734. The temperature of each electrode unit 33 of the electrode plate 13 includes the temperature of each electrode unit 33 in the over-temperature region and the temperature of each electrode unit 33 in the non-over-temperature region.

[0216] Step 732: Determine whether the temperature of each electrode unit 33 in the overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the overheated area does not exceed the first preset temperature t1, execute step 733. If there is a temperature in each electrode unit 33 in the overheated area that exceeds the first preset temperature t1, return to step 731.

[0217] Step 733: Re-determine the area as a non-overheated zone and proceed to step 734;

[0218] Step 734: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1, execute step 735. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the first preset temperature t1, execute step 736.

[0219] Step 735: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area by increasing the voltage or current amplitude of the currently applied alternating current signal and return to step 712;

[0220] Step 736: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2, execute step 737. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the second preset temperature t2, execute step 738.

[0221] Step 737: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and return to step 712;

[0222] Step 738: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the preset temperature threshold t0. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the preset temperature threshold t0, proceed to step 739. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the preset temperature threshold t0, return to step 719.

[0223] Step 739: Continue to apply alternating electrical signals to each electrode unit 33 in the non-overheated area by reducing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 712.

[0224] Specifically, the process in step 711 where the combined control is electrically connected to the control switch 54 and the bidirectional switching switch 55 of the corresponding electrode sheet 13 to apply alternating electrical signals to each electrode unit 33 of the electrode sheet is as follows:

[0225] Disconnect all control switches 54 electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 electrically connected to the corresponding electrode piece 13 to the end that applies an alternating electrical signal to each electrode unit 33; or

[0226] Disconnect all control switches 54 electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 electrically connected to the corresponding electrode piece 13 to the end that electrically connects each electrode unit 33 to the alternating power supply line 57; or

[0227] Disconnect all control switches 54 that are electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 that are electrically connected to the corresponding electrode piece 13 to their respective terminals 2.

[0228] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 712, 722, and 731 is as follows:

[0229] The power supply switch 40 of the control electric field generator 30 is used to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode plate 13. Each of the bidirectional switching switches 55 electrically connected to the electrode plate 13 is controlled to sequentially switch from its end that applies alternating electrical signals to each electrode unit 33 to its end that performs temperature acquisition. The remaining bidirectional switching switches 55 are switched from their temperature acquisition ends to their alternating electrical signal ends. The control switch 54 electrically connected to the electrode unit 33 of the electrode plate 13 is then sequentially closed to obtain the temperature of each electrode unit 33.

[0230] The power supply switch 40 of the control electric field generator 30 is used to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode plate 13. Each bidirectional switching switch 55 electrically connected to the electrode plate 13 is controlled to sequentially switch from its two ends that apply alternating electrical signals to each electrode unit 33 to its one end in a time-sharing manner. The remaining bidirectional switching switches 55 are switched from their one ends to their two ends that apply alternating electrical signals to each electrode unit 33 in a time-sharing manner. The control switch 54 electrically connected to the electrode unit 33 of the electrode plate 13 is then sequentially closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode plate 13; or

[0231] The power supply switch 40 of the control electric field generator 30 is used to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode plate 13. Each bidirectional switching switch 55 electrically connected to the electrode plate 13 is controlled to sequentially switch the electrode plate 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52. The remaining bidirectional switching switches 55 are switched from being electrically connected to the corresponding ADC unit 52 to being electrically connected to the alternating power line 57. The control switches 54 electrically connected to each electrode unit 33 of the electrode plate 13 are closed sequentially to obtain the temperature of each electrode unit 33 of the electrode plate 13.

[0232] The power supply switch 40 of the control electric field generator 30 is used to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode plate 13. The control switch 55 of the bidirectional switching switches 55 electrically connected to the electrode plate 13 is used to sequentially switch each electrode unit 33 of the electrode plate 13 from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals. The remaining bidirectional switching switches 55 switch from transmitting direct current signals or temperature detection signals to transmitting alternating electrical signals. The control switches 54 electrically connected to each electrode unit 33 of the electrode plate 13 are closed sequentially to obtain the temperature of each electrode unit 33 of the electrode plate 13.

[0233] The first preset temperature in steps 713, 723, 726, 732, and 734 is 40℃-40.3℃, preferably 40.2℃. The second preset temperature in steps 715, 728, and 736 is 40.4℃ to 40.6℃, preferably 40.5℃; the preset temperature threshold in steps 717 and 738 is 41℃ to 41.5℃, preferably 41℃; the preset quantity threshold in step 720 is preferably 2.

[0234] The process of continuing to apply the alternating electrical signal as described in steps 714, 716, 718, 727, 729, 730, 735, 737, and 739 is as follows:

[0235] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals to conduct the alternating electrical signal transmission path electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0236] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals to switch from its respective terminal 1 to its respective terminal 2, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0237] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue receiving alternating electrical signals, and simultaneously control the two ends of the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue receiving alternating electrical signals to be electrically connected to the alternating power supply line 57, so as to continue to apply alternating electrical signals to the electrode unit 33 that needs to continue receiving alternating electrical signals; or

[0238] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals so that its two ends are closed and its one end is open, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0239] The control switch 54, which is electrically connected to the electrode unit 33 that needs to continue to apply alternating electrical signals, is disconnected, and at the same time, the bidirectional switching switch 55, which is electrically connected to the electrode unit 33 that needs to continue to apply alternating electrical signals, is controlled to switch the electrode unit 33 that needs to continue to apply alternating electrical signals from transmitting temperature detection signals to applying alternating electrical signals.

[0240] The increase in the voltage or current amplitude of the currently applied alternating current signal in steps 714, 727, and 735 specifically involves boosting the voltage of the currently applied alternating current signal by increasing the DC voltage amplitude by 0.03V per second.

[0241] The method of continuing to apply the alternating current signal by reducing the voltage or current amplitude of the currently applied alternating current signal as described in steps 718, 730, and 739 specifically means continuing to apply the alternating current signal by reducing the voltage amplitude of the currently applied alternating current signal by 5V for 3 minutes.

[0242] The process of stopping the application of alternating electrical signals to each electrode unit 33 of the electrode sheet 13 as described in step 721 is as follows:

[0243] The bidirectional switching switch 55, which controls the electrical connection between the electrode unit 33 of the electrode 13 and the alternating power line 57, disconnects the electrical connection between the electrode unit 33 of the electrode 13 and the alternating power line 57; or

[0244] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, is switched from the end that applies alternating electrical signals to each electrode unit 33 to the end that allows each electrode unit 33 to acquire temperature; or

[0245] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, switches all two terminals that apply alternating electrical signals to each electrode unit 33 to one terminal; or

[0246] The bidirectional switching switch 55, which is electrically connected to the electrode 13, switches the electrode 13 from being electrically connected to the alternating power line 57 for each electrode unit 33 to being electrically connected to the corresponding ADC unit 52 for each electrode unit 33; or

[0247] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, controls the switching of each electrode unit 33 of the electrode plate 13 from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals.

[0248] The process of stopping the application of alternating electrical signals to each electrode unit 33 in the over-temperature region as described in step 725 is as follows:

[0249] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone and the alternating power line 57, disconnects the electrical connection between each electrode unit 33 in the over-temperature zone and the alternating power line 57; or

[0250] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, is switched from the end that applies alternating electrical signals to each electrode unit 33 in the over-temperature zone to the end that allows each electrode unit 33 in the over-temperature zone to acquire temperature data; or

[0251] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, switches all two terminals that apply alternating electrical signals to each electrode unit 33 in the over-temperature zone to one terminal; or

[0252] The bidirectional switching switch 55, which controls the electrical connection of each electrode unit 33 in the over-temperature zone, switches each electrode unit 33 in the over-temperature zone from being electrically connected to the alternating power line 57 to being electrically connected to its corresponding ADC unit 52; or

[0253] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, switches each electrode unit 33 in the over-temperature zone from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals.

[0254] In the above control method, the tumor electric field therapy system 100 includes at least two pairs of electrode plates 13 to alternately apply alternating electric fields with different directions. Each electrode plate 13 can alternately switch between applying an alternating electric signal and transmitting a temperature detection signal.

[0255] The tumor electric field therapy system 100 of this application embodiment further includes a third preset temperature t3 in the first controller 51 or electric field generator 30 within the adapter 20. The third preset temperature t3 is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. This application embodiment also provides an alternating electrical signal control method based on a temperature detection signal for use in the aforementioned tumor electric field therapy system. Figure 16 As shown, the alternating current signal control method includes:

[0256] Step 810: Activate the tumor electric field therapy system 100;

[0257] Step 811: Combine the control switch 54 (also called grounding switch) and the bidirectional switching switch 55 that are electrically connected to the corresponding electrode plate 13 to apply alternating electrical signals to each electrode unit 33 of the electrode plate 13;

[0258] Step 812: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to obtain the temperature of each electrode unit 33 of the electrode plate 13;

[0259] Step 813: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 33 with a temperature exceeding the first preset temperature t1, proceed to step 814. If there is an electrode unit 33 with a temperature exceeding the first preset temperature t1, proceed to step 815.

[0260] Step 814: Continue to apply alternating current signals to each electrode unit 33 of electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0261] Step 815: Determine whether there is an electrode unit 33 with a temperature exceeding the second preset temperature t2; if there is no electrode unit 33 with a temperature exceeding the second preset temperature t2, proceed to step 816; if there is an electrode unit 33 with a temperature exceeding the second preset temperature t2, proceed to step 817.

[0262] Step 816: Continue to apply alternating current signals to each electrode unit 33 of electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and return to step 812;

[0263] Step 817: Determine whether there is an electrode unit 33 with a temperature exceeding the third preset temperature t3. If there is no electrode unit 33 with a temperature exceeding the third preset temperature t3, proceed to step 818; if there is an electrode unit with a temperature exceeding the third preset temperature t3, proceed to step 819.

[0264] Step 818: Continue to apply alternating current signals to all electrode units 33 of electrode sheet 13 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0265] Step 819: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, proceed to step 820; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, proceed to step 821.

[0266] Step 820: Continue to apply the alternating current signal to all electrode units 33 of electrode sheet 13 in a manner that further reduces the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0267] Step 821: Determine the number of overheated areas and proceed to step 822, wherein the overheated area is the area containing electrode units whose temperature exceeds the preset temperature threshold t0, and the non-overheated area is the area where the temperature of all electrode units does not exceed the preset temperature threshold t0.

[0268] Step 822: Determine whether the number of overheated areas exceeds the preset number threshold. If the number of overheated areas exceeds the preset number threshold, proceed to step 823. If the number of overheated areas does not exceed the preset number threshold, proceed to step 826.

[0269] Step 823: Stop applying alternating electrical signals to each electrode unit 33 of the electrode sheet 13 and proceed to step 824;

[0270] Step 824: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to obtain the temperature of each electrode unit 33 of the electrode plate 13 and execute step 825;

[0271] Step 825: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If there is no electrode unit 33 with a temperature exceeding the first preset temperature t1 on the electrode sheet 13, return to step 811. If there is an electrode unit 33 with a temperature exceeding the first preset temperature t1 on the electrode sheet 13, return to step 824.

[0272] Step 826: Distinguish between overheated and non-overheated regions based on whether there is an electrode unit 33 with a temperature exceeding the preset temperature threshold t0. If the region is an overheated region, proceed to step 827; if the region is a non-overheated region, proceed to step 828.

[0273] Step 827: Stop applying alternating electrical signals to each electrode unit 33 in the over-temperature region and proceed to step 835;

[0274] Step 828: Determine whether the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1, proceed to step 829. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the first preset temperature t1, proceed to step 830.

[0275] Step 829: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area of ​​electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating current signal and execute step 835;

[0276] Step 830: Determine whether the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2, execute step 831. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the second preset temperature t2, execute step 832.

[0277] Step 831: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area of ​​electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and execute step 835;

[0278] Step 832: Determine whether there are any electrode units 33 in the non-overheated area whose temperature exceeds the third preset temperature t3. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the third preset temperature t3, execute step 833. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the third preset temperature t3, execute step 834.

[0279] Step 833: Continue to apply alternating current signals to each electrode unit 33 in the non-over-temperature region of electrode sheet 13 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal and execute step 835;

[0280] Step 834: Continue to apply alternating current signals to each electrode unit 33 in the non-over-temperature region of electrode sheet 13 in a manner that further reduces the voltage or current amplitude of the currently applied alternating current signal and proceed to step 835;

[0281] Step 835: Combine the control switch 54 and the bidirectional switching switch 55 that are electrically connected to the electrode plate 13 to reacquire the temperature of each electrode unit 33 of the electrode plate 13 and select to execute step 836 or step 838. The temperature of each electrode unit 33 of the electrode plate 13 includes the temperature of each electrode unit 33 in the over-temperature region and the temperature of each electrode unit 33 in the non-over-temperature region.

[0282] Step 836: Determine whether the temperature of each electrode unit 33 in the overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the overheated area does not exceed the first preset temperature t1, proceed to step 837. If there is a temperature in each electrode unit 33 in the overheated area that exceeds the first preset temperature t1, return to step 835.

[0283] Step 837: Re-determine the area as a non-overheated zone and proceed to step 838;

[0284] Step 838: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the first preset temperature t1, execute step 839. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the first preset temperature t1, execute step 840.

[0285] Step 839: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area by increasing the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0286] Step 840: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the second preset temperature t2, execute step 841. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the second preset temperature t2, execute step 842.

[0287] Step 841: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal constant, and return to step 812;

[0288] Step 842: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the third preset temperature t3. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the third preset temperature t3, execute step 843. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the third preset temperature t3, execute step 844.

[0289] Step 843: Continue to apply alternating current signals to each electrode unit 33 in the non-overheated area by reducing the voltage or current amplitude of the currently applied alternating current signal and return to step 812;

[0290] Step 844: Determine whether the temperature of each electrode unit 33 in the obtained non-overheated area does not exceed the preset temperature threshold t0. If the temperature of each electrode unit 33 in the non-overheated area does not exceed the preset temperature threshold t0, proceed to step 845. If there is a temperature in each electrode unit 33 in the non-overheated area that exceeds the preset temperature threshold t0, return to step 821.

[0291] Step 845: Continue to apply alternating electrical signals to each electrode unit 33 of the non-overheated region in a manner that further reduces the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812.

[0292] Specifically, the process in step 811 where the combined control is electrically connected to the control switch 54 and the bidirectional switching switch 55 of the corresponding electrode sheet 13 to apply alternating electrical signals to each electrode unit 33 of the electrode sheet is as follows:

[0293] Disconnect all control switches 54 electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 electrically connected to the corresponding electrode piece 13 to the end that applies an alternating electrical signal to each electrode unit 33; or

[0294] Disconnect all control switches 54 electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 electrically connected to the corresponding electrode piece 13 to the end that electrically connects each electrode unit 33 to the alternating power supply line 57; or

[0295] Disconnect all control switches 54 that are electrically connected to the corresponding electrode piece 13, and simultaneously switch all bidirectional switching switches 55 that are electrically connected to the corresponding electrode piece 13 to their respective terminals 2.

[0296] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 812, 824, and 835 is as follows:

[0297] The power supply switch 40 of the control electric field generator 30 is used to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode plate 13. Each of the bidirectional switching switches 55 electrically connected to the electrode plate 13 is controlled to sequentially switch from its end that applies alternating electrical signals to each electrode unit 33 to its end that performs temperature acquisition. The remaining bidirectional switching switches 55 are switched from their temperature acquisition ends to their alternating electrical signal ends. The control switch 54 electrically connected to the electrode unit 33 of the electrode plate 13 is then sequentially closed to obtain the temperature of each electrode unit 33.

[0298] The power supply switch 40 of the control electric field generator 30 is used to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode plate 13. Each bidirectional switching switch 55 electrically connected to the electrode plate 13 is controlled to sequentially switch from its two ends that apply alternating electrical signals to each electrode unit 33 to its one end in a time-sharing manner. The remaining bidirectional switching switches 55 are switched from their one ends to their two ends that apply alternating electrical signals to each electrode unit 33 in a time-sharing manner. The control switch 54 electrically connected to the electrode unit 33 of the electrode plate 13 is then sequentially closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode plate 13; or

[0299] The power supply switch 40 of the control electric field generator 30 is used to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode plate 13. Each bidirectional switching switch 55 electrically connected to the electrode plate 13 is controlled to sequentially switch the electrode plate 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52. The remaining bidirectional switching switches 55 are switched from being electrically connected to the corresponding ADC unit 52 to being electrically connected to the alternating power line 57. The control switches 54 electrically connected to each electrode unit 33 of the electrode plate 13 are closed sequentially to obtain the temperature of each electrode unit 33 of the electrode plate 13.

[0300] The power supply switch 40 of the control electric field generator 30 is used to disconnect the alternating electrical signal applied to each electrode unit 33 of the electrode plate 13. The control switch 55 of the bidirectional switching switches 55 electrically connected to the electrode plate 13 is used to sequentially switch each electrode unit 33 of the electrode plate 13 from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals. The remaining bidirectional switching switches 55 switch from transmitting direct current signals or temperature detection signals to transmitting alternating electrical signals. The control switches 54 electrically connected to each electrode unit 33 of the electrode plate 13 are closed sequentially to obtain the temperature of each electrode unit 33 of the electrode plate 13.

[0301] The first preset temperature in steps 813, 825, 828, 836, and 838 is 40℃-40.3℃, preferably 40.2℃. The second preset temperature in steps 815, 830, and 840 is 40.4℃ to 40.6℃, preferably 40.5℃; the third preset temperature in steps 817, 832, and 842 is 40.7℃ to 40.9℃, preferably 40.8℃; the preset temperature threshold in steps 819 and 844 is 41℃ to 41.5℃, preferably 41℃; and the preset quantity threshold in step 822 is preferably 2.

[0302] The process of continuing to apply the alternating electrical signal as described in steps 814, 816, 818, 820, 829, 831, 833, 834, 839, 841, 843, and 845 is specifically as follows:

[0303] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals to conduct the alternating electrical signal transmission path electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0304] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals to switch from its respective terminal 1 to its respective terminal 2, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0305] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue receiving alternating electrical signals, and simultaneously control the two ends of the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue receiving alternating electrical signals to be electrically connected to the alternating power supply line 57, so as to continue to apply alternating electrical signals to the electrode unit 33 that needs to continue receiving alternating electrical signals; or

[0306] Disconnect the control switch 54 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals, and simultaneously control the bidirectional switching switch 55 electrically connected to the electrode unit 33 that needs to continue applying alternating electrical signals so that its two ends are closed and its one end is open, thereby continuing to apply alternating electrical signals to the electrode unit 33 that needs to continue applying alternating electrical signals; or

[0307] The control switch 54, which is electrically connected to the electrode unit 33 that needs to continue to apply alternating electrical signals, is disconnected, and at the same time, the bidirectional switching switch 55, which is electrically connected to the electrode unit 33 that needs to continue to apply alternating electrical signals, is controlled to switch the electrode unit 33 that needs to continue to apply alternating electrical signals from transmitting temperature detection signals to applying alternating electrical signals.

[0308] The method of increasing the voltage or current amplitude of the currently applied alternating signal in steps 814, 829, and 839 specifically refers to boosting the voltage of the currently applied alternating signal by increasing the DC voltage amplitude by 0.03V per second before continuing to apply the alternating signal.

[0309] The method of continuing to apply the alternating current signal by reducing the voltage or current amplitude of the currently applied alternating current signal as described in steps 818, 820, 833, 834, 843, and 845 specifically refers to continuing to apply the alternating current signal by reducing the voltage amplitude of the currently applied alternating current signal by 5V for 3 minutes.

[0310] The process of stopping the application of alternating electrical signals to each electrode unit 33 of the electrode sheet 13 as described in step 823 is as follows:

[0311] The bidirectional switching switch 55, which controls the electrical connection between the electrode unit 33 of the electrode 13 and the alternating power line 57, disconnects the electrical connection between the electrode unit 33 of the electrode 13 and the alternating power line 57; or

[0312] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, is switched from the end that applies alternating electrical signals to each electrode unit 33 to the end that allows each electrode unit 33 to acquire temperature; or

[0313] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, switches all two terminals that apply alternating electrical signals to each electrode unit 33 to one terminal; or

[0314] The bidirectional switching switch 55, which is electrically connected to the electrode 13, switches the electrode 13 from being electrically connected to the alternating power line 57 for each electrode unit 33 to being electrically connected to the corresponding ADC unit 52 for each electrode unit 33; or

[0315] The bidirectional switching switch 55, which is electrically connected to the electrode plate 13, controls the switching of each electrode unit 33 of the electrode plate 13 from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals.

[0316] The process of stopping the application of alternating electrical signals to each electrode unit 33 in the over-temperature region as described in step 827 is as follows:

[0317] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone and the alternating power line 57, disconnects the electrical connection between each electrode unit 33 in the over-temperature zone and the alternating power line 57; or

[0318] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, is switched from the end that applies alternating electrical signals to each electrode unit 33 in the over-temperature zone to the end that allows each electrode unit 33 in the over-temperature zone to acquire temperature data; or

[0319] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, switches all two terminals that apply alternating electrical signals to each electrode unit 33 in the over-temperature zone to one terminal; or

[0320] The bidirectional switching switch 55, which controls the electrical connection of each electrode unit 33 in the over-temperature zone, switches each electrode unit 33 in the over-temperature zone from being electrically connected to the alternating power line 57 to being electrically connected to its corresponding ADC unit 52; or

[0321] The bidirectional switching switch 55, which controls the electrical connection between each electrode unit 33 in the over-temperature zone, switches each electrode unit 33 in the over-temperature zone from transmitting alternating electrical signals to transmitting direct current signals or temperature detection signals.

[0322] When the tumor electric field therapy system 100 is in standby mode before starting work, no alternating electrical signal is applied to the electrode unit 33. The first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the switching sequence of each bidirectional switching switch 55 and each control switch 54, so that the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to each row of electrode units 33 (33-1 to 33-20) in sequence.

[0323] The first controller 51 receives the temperature detection signals of the temperature detection units 35 corresponding to each electrode unit 33 (33-1 to 33-20) through the ADC unit 52, and transmits them to the AC signal generator 39 of the electric field generator 30 through the first communication unit 56 and the second communication unit 38. Then, the second controller 37 controls or adjusts the alternating electrical signals applied to each electrode unit 33.

[0324] Although the operations are depicted in the accompanying drawings in a specific order, this should not be construed as requiring that the operations be performed in the specific order shown or in chronological order, nor should it be construed as requiring that all the operations shown be performed to obtain the desired result.

[0325] Example 2:

[0326] In the tumor electric field therapy system 100 shown in Embodiment 1, some adjacent electrode units 33 in the electrode sheet 13 are connected by a connecting strip (not labeled). The connection method of the 10 electrode units 33 on the left side of the electrode sheet 13 is asymmetrical with the connection method of the 10 electrode units 33 on the right side. The 10 electrode units 33 on the left side of the electrode sheet 13 have 4 electrode units 33 with free ends, and the 10 electrode units 33 on the right side of the electrode sheet 13 have 5 electrode units 33 with free ends. Unlike the tumor electric field therapy system 100 shown in Embodiment 1, the reference... Figure 17 The following describes another tumor electric field therapy system 100A, whose main concept is the same as that of the tumor electric field therapy system 100 described above, and whose spatial arrangement of electrode units 33A is the same as that of the electrode units 33A of the tumor electric field therapy system 100 shown in Example 1. The difference is that the connection method of electrode units 33A in electrode sheet 13A of this tumor electric field therapy system 100A is different. The connection method of the 10 electrode units 33A on the left side of electrode sheet 13A is symmetrical to that of the 10 electrode units 33A on the right side. The 10 electrode units 33A on the left side of electrode sheet 13A have 4 electrode units 33A at free ends, and the 10 electrode units 33A on the right side of electrode sheet 13A have 4 electrode units 33A at free ends. Specifically, along the column upwards, only the adjacent two electrode units 33 in the third and fourth columns are connected by a connecting strip (unlabeled), while the adjacent two electrode units 33 in the other four columns are not connected by a connecting strip. The bridging part (unlabeled) connects the two opposite connecting strips (unlabeled) in the column upwards.

[0327] Other contents in this embodiment are similar to those in Embodiment 1 above, and will not be repeated here.

[0328] Example 3:

[0329] In the tumor electric field therapy system 100 shown in Embodiment 1, each electrode sheet 13 includes 20 electrode units 33. Unlike the tumor electric field therapy system 100 shown in Embodiment 1, the reference... Figure 18 and Figure 19The following describes another tumor electric field therapy system 100B, whose main concept is the same as the tumor electric field therapy system 100 described above. The difference is that each electrode sheet 13B of the tumor electric field therapy system 100B includes 13 electrode units 33B. Each electrode sheet 13B does not have an electrode unit 33B at a free end, and the number of electrode units 33B included in each row and column group of each electrode sheet 13B is different. Specifically, these 13 electrode units 33B are arranged in a spatial structure of five rows and five columns. Each of the first and fifth rows includes two electrode units 33B, and the two electrode units 33B in each row are located in the second and fourth columns, respectively. Each of the second to fourth rows includes three electrode units 33B, and the three electrode units 33B in each row are located in the first, third, and fifth columns, respectively. In each of the five rows of electrode units 33B, adjacent electrode units 33B are connected by a connecting strip (unnumbered). Similarly, adjacent electrode units 33B in the first, third, and fifth columns are connected by a connecting strip (unnumbered). The electrode unit 33B in the second column of the first row is connected to the electrode units 33B in the first and third columns of the second row by a connecting strip (unnumbered); the electrode unit 33B in the fourth column of the first row is connected to the electrode units 33B in the third and fifth columns of the second row by a connecting strip (unnumbered); the electrode unit 33B in the second column of the fifth row is connected to the electrode units 33B in the first and third columns of the fourth row by a connecting strip (unnumbered); and the electrode unit 33B in the fourth column of the fifth row is connected to the electrode units 33B in the third and fifth columns of the fourth row by a connecting strip (unnumbered).

[0330] Figure 19 for Figure 18 The diagram shows the circuit connection between the electrode pad 13B and the adapter 20B of the tumor electric field therapy system 100B. Multiple electrode units 33B are configured into multiple row groups and multiple column groups in the circuit connection. In this embodiment, each electrode pad 13B has 13 electrode units 33B. The 13 electrode units 33B are grouped in the circuit connection according to the order 1 to 13. Electrode units 33-1B to 33-13B are divided into three row groups and five column groups, that is, the 13 electrode units 33B are arranged in three rows and five columns in the circuit connection. The first and second row groups each include 5 electrode units 33B, the third row group includes 3 electrode units 33B, the first to third column groups each include 3 electrode units 33B, and the fourth to fifth column groups each include 2 electrode units 33B.

[0331] Electrode plate 13B includes five grounding wires 18B, namely the first grounding wire 18-1B, the second grounding wire 18-2B, the third grounding wire 18-3B, the fourth grounding wire 18-4B, and the fifth grounding wire 18-5B. Each of the five grounding wires 18B corresponds to one of the five column groups. In the five column groups of electrode plate 13B, the first column group includes electrode units 33-1B, 33-6B, and 33-11B; the second column group includes electrode units 33-2B, 33-7B, and 33-12B; the third column group includes electrode units 33-3B, 33-8B, and 33-13B; the fourth column group includes electrode units 33-4B and 33-9B; and the fifth column group includes electrode units 33-5B and 33-10B. Specifically, the first grounding wire 18-1B is used to ground the grounding terminal 35-1B of the corresponding temperature detection unit 35B of each of the electrode units 33-1B, 33-6B, and 33-11B in the first column group; the second grounding wire 18-2B is used to ground the grounding terminal 35-1B of the corresponding temperature detection unit 35B of each of the electrode units 33-2B, 33-7B, and 33-12B in the second column group; the third grounding wire 18-3B is used to ground the grounding terminal 35-1B of the corresponding temperature detection unit 35B of each of the electrode units 33-2B, 33-7B, and 33-12B in the third column group. The grounding terminal 35-1B of the corresponding temperature detection unit 35B of each of electrode units 3-3B, 33-8B, and 33-13B is grounded; the fourth grounding wire 18-4B is used to ground the grounding terminal 35-1B of the corresponding temperature detection unit 35B of each of electrode units 33-4B and 33-9B in the fourth column group; the fifth grounding wire 18-5B is used to ground the grounding terminal 35-1B of the corresponding temperature detection unit 35B of each of electrode units 33-5B and 33-10B in the fifth column group.

[0332] Unlike Embodiment 1 or Embodiment 2 above, the multi-channel dual-purpose signal line 19B in this embodiment only includes three dual-purpose signal lines: a first dual-purpose signal line 19-1B, a second dual-purpose signal line 19-2B, and a third dual-purpose signal line 19-3B. The first dual-purpose signal line 19-1B, the second dual-purpose signal line 19-2B, and the third dual-purpose signal line 19-3B are respectively configured one-to-one with the three rows of electrode units 33B of the electrode sheet 13B. Specifically, the five electrode units 33B from electrode units 33-1B to electrode units 33-5B are connected in series to the first dual-purpose signal line 19-1B, and the temperature detection units 35B corresponding to each of the five electrode units 33B from electrode units 33-1B to electrode units 33-5B are connected in series to the first dual-purpose signal line 19-1B; the five electrode units 33B from electrode units 33-6B to electrode units 33-10B are connected in series to the second dual-purpose signal line 19-2B, and the electrode units 33- The temperature detection units 35B corresponding to each of the five electrode units 33B (6B to 33-10B) are connected in series and then connected to the second dual-purpose signal line 19-2B. The three electrode units 33B (33-11B to 33-13B) are connected in series and then connected to the third dual-purpose signal line 19-3B. Furthermore, the temperature detection units 35B corresponding to each of the three electrode units 33B (33-11B to 33-13B) are also connected in series and then connected to the third dual-purpose signal line 19-3B. Of course, in some examples, the multi-channel dual-purpose signal line 19B may also include four dual-purpose signal lines, where the fourth dual-purpose signal line is not electrically connected to the signal terminal of any temperature detection unit.

[0333] Specifically, in this embodiment, the multiple control switches 54B in the corresponding group of control switches 54B are respectively a first control switch 54-1B, a second control switch 54-2B, a third control switch 54-3B, a fourth control switch 54-4B, and a fifth control switch 54-5B. The first control switch 54-1B, the second control switch 54-2B, the third control switch 54-3B, the fourth control switch 54-4B, and the fifth control switch 54-5B each control the closing or opening of the corresponding grounding wire 18B of the same electrode plate 13B. The first control switch 54-1B is used to control the opening or closing of the first grounding wire 18-1B of the corresponding electrode plate 13B, and can then cooperate with the corresponding set of bidirectional switching switches 55B to control the energization and de-energization of the temperature detection units 35B corresponding to the three electrode units 33B (33-1B, 33-6B, and 33-11B) in the first column of the electrode plate 13B; the second control switch 54-2B is used to control the opening or closing of the second grounding wire 18-2B of the electrode plate 13B, and can then cooperate with the corresponding set of bidirectional switching switches 55B to control multiple electrode units (which can be electrode unit 33-1B and electrode unit 33-2B) in the first and second columns of the electrode plate 13B. B. The temperature detection units 35B corresponding to electrode units 33-6B, 33-7B, 33-11B, and 33-12B are energized and de-energized; the third control switch 54-3B is used to control the closing or opening of the third grounding wire 18-3B of the electrode plate 13B, and can then cooperate with the corresponding bidirectional switching switch 55B to control the energization and de-energization of each temperature detection unit 35B corresponding to multiple electrode units (electrode units 33-1B to 33-3B, electrode units 33-6B to 33-8B, and electrode units 33-11B to 33-13B) in the first, second, and third columns of the electrode plate 13B; the fourth control switch 54-4B and the fifth control switch 54-5B are similar.

[0334] Taking the electrical connection between an electrode 13B and an adapter 20B as an example, the multiple bidirectional switches 55B in the corresponding group of bidirectional switches 55B are respectively the first bidirectional switch 55-1B, the second bidirectional switch 55-2B, the third bidirectional switch 55-3B, and the fourth bidirectional switch 55-4B. The first bidirectional switch 55-1B, the second bidirectional switch 55-2B, and the third bidirectional switch 55-3B control the switching of a corresponding dual-purpose signal line 19B in the multi-channel dual-purpose signal line 19B of the same electrode 13B between transmitting alternating electrical signals and transmitting temperature detection signals. Specifically, the first bidirectional switching switch 55-1B is used to control the switching of the first dual-purpose signal line 19-1B of the corresponding electrode pad 13B between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of each electrode unit 33B (from electrode unit 33-1B to electrode unit 33-5B) in the first row of the electrode pad 13B and the conduction of the signal terminals 35-2B of each temperature detection unit 35B corresponding to each electrode unit 33-1B to electrode unit 33-5B in the first row of the electrode pad 13B. It also cooperates with the corresponding first control switch 54-1B, second control switch 54-2B, third control switch 54-3B, fourth control switch 54-4B, and fifth control switch 54-5B to ensure that the first row of electrode units 33-1B to electrode units 33-5B transmits alternating electrical signals to the patient, or that the temperature detection signals detected by one or more combinations of the temperature detection units 35B corresponding to these electrode units 33B are sampled and output to the corresponding ADC unit 52B. The second bidirectional switching switch 55-2B is used to control the switching of the second dual-purpose signal line 19-2B of the corresponding electrode 13B between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of each electrode unit 33B in the second row of electrode units 33-6B to 33-10B and the conduction of the signal terminals 35-2B of each temperature detection unit 35B corresponding to the electrode units 33-6B to 33-10B in the second row of electrode units 33-6B to 33-10B. It also works in conjunction with the corresponding first control switch 54-1B, second control switch 54-2B, third control switch 54-3B, fourth control switch 54-4B, and fifth control switch 54-5B to enable the second row of electrode units 33-6B to 33-10B to transmit alternating electrical signals to the patient or to sample and output the temperature detection signals detected by one or more combinations of the temperature detection units 35B corresponding to these electrode units 33B to the corresponding ADC unit 52B.The third bidirectional switching switch 55-3B is used to control the switching of the third dual-purpose signal line 19-3B of the corresponding electrode 13B between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of electrode units 33-11B to each electrode unit 33B in the third row of the electrode 13B and the conduction of the signal terminals 35-2B of each temperature detection unit 35B corresponding to electrode unit 33-13B in the third row of the electrode 13B, and the corresponding first control switch 54-1B. The second control switch 54-2B and the third control switch 54-3B cooperate to enable the third row of electrode units 33-11B to 33-13B to transmit alternating electrical signals to the patient, or to sample and output the temperature detection signals detected by one or more combinations of temperature detection units 35B corresponding to these electrode units 33B to the corresponding ADC units; the fourth bidirectional switch 55-4B does not correspond to any row group (it is not connected to any dual-purpose signal line), therefore, signal control is not required through the fourth bidirectional switch 55-4B.

[0335] Other contents in this embodiment are similar to those in Embodiment 1 above, and will not be repeated here.

[0336] Example 4:

[0337] In the tumor electric field therapy system 100B shown in Embodiment 3, the terminal electrode unit 33B among the 13 electrode units 33B in each electrode sheet 13B is not freely disposed. Unlike the tumor electric field therapy system 100B shown in Embodiment 3, the reference... Figure 20 Another tumor electric field therapy system 100C shares the same basic concept as the aforementioned tumor electric field therapy system 100B, but differs in the connection method of the connecting strips (unlabeled) in the electrode pads 13C. The 13 electrode units 33C include two electrode units 33C located at their free ends. Specifically, Figure 20 In the electrode pad 13C of the tumor electric field therapy system 100C shown, no connecting strip is provided between the electrode unit 33C located in the first row and second column and the two electrode units 33C located in the first row and fourth column, and the second row and first column; no connecting strip is provided between the electrode unit 33C located in the fifth row and fourth column and the two electrode units 33C located in the fifth row and second column, and the fourth row and fifth column; no connecting strip is provided between the two electrode units 610 located in the second row and fifth column, and the third row and fifth column; no connecting strip is provided between the two electrode units 610 located in the second row and fifth column, and the third row and fifth column. The connecting strips (not shown) of the electrode pad 100C are arranged in this way to form corresponding open spaces and free ends, facilitating application.

[0338] Other contents in this embodiment are similar to those in embodiment 3 above, and will not be repeated here.

[0339] Example 5:

[0340] In the tumor electric field therapy system 100B shown in Embodiment 3, the 13 electrode units 33 in each electrode sheet 13B are connected by 22 connecting strips. Unlike the tumor electric field therapy system 100B shown in Embodiment 3, reference... Figure 21 Another tumor electric field therapy system 100D shares the same basic concept as the aforementioned tumor electric field therapy system 100B, but differs in that the 13 electrode units 33D within each electrode sheet 13D of this system are connected by 18 connecting strips. Specifically, Figure 21 In the electrode pads 13D of the tumor electric field therapy system 100D shown, no connecting strips are provided between adjacent electrode units 33D in the first and fifth rows; no connecting strips are provided between two electrode units 33D in the first and third columns of the second row; and no connecting strips are provided between two electrode units 33D in the third and fifth columns of the fourth row. This arrangement of the connecting strips (not shown) on the electrode pads 100D creates corresponding open spaces and free ends, facilitating application.

[0341] Other contents in this embodiment are similar to those in embodiment 3 above, and will not be repeated here.

[0342] Example 6:

[0343] Unlike the tumor electric field therapy system 100B shown in Example 3, the reference... Figure 22 The following describes another tumor electric field therapy system 100E, which is similar in concept to the tumor electric field therapy system 100B described above, except that the number of electrode units 33E contained in each row and column group of each electrode sheet 13E in the circuit connection of the tumor electric field therapy system 100E is different.

[0344] Figure 22This is a schematic diagram of the circuit connection between the electrode pad 13E and the adapter 20E of the tumor electric field therapy system 100E. Multiple electrode units 33E are configured into multiple row groups and multiple column groups. In this embodiment, each electrode pad 13E has 13 electrode units 33E. The 13 electrode units 33E are grouped in the circuit connection according to the order 1 to 13. Electrode units 33-1E to 33-13E are divided into four row groups and four column groups, that is, the 13 electrode units 33E are arranged in four rows and four columns in the circuit connection. Each row in the first to third row groups includes 4 electrode units 33E, and the fourth row group includes 1 electrode unit 33E. The first column group includes 4 electrode units 33E, and each of the second to fourth column groups includes 3 electrode units 33E.

[0345] The electrode plate 13E includes four grounding wires 18E, namely the first grounding wire 18-1E, the second grounding wire 18-2E, the third grounding wire 18-3E, and the fourth grounding wire 18-4E. The first grounding wire 18-1E, the second grounding wire 18-2E, the third grounding wire 18-3E, and the fourth grounding wire 18-4E are respectively set to correspond one-to-one with the four column groups. In the four column groups of the electrode plate 13E, the first column group includes electrode units 33-1E, 33-5E, 33-9E, and 33-13E; the second column group includes electrode units 33-2E, 33-6E, and 33-10E; the third column group includes electrode units 33-3E, 33-7E, and 33-11E; and the fourth column group includes electrode units 33-4E, 33-8E, and 33-12E. Specifically, the first grounding wire 18-1E is used to ground the grounding terminal 35-1E of the corresponding temperature detection unit 35E of each of the electrode units 33-1E, 33-5E, 33-9E, and 33-13E in the first column group; the second grounding wire 18-2E is used to ground the grounding terminal 35-1E of the corresponding temperature detection unit 35E of each of the electrode units 33-2E, 33-6E, and 33-10E in the second column group; the third grounding wire 18-3E is used to ground the grounding terminal 35-1E of the corresponding temperature detection unit 35E of each of the electrode units 33-3E, 33-7E, and 33-11E in the third column group; and the fourth grounding wire 18-4E is used to ground the grounding terminal 35-1E of the corresponding temperature detection unit 35E of each of the electrode units 33-4E, 33-8E, and 33-12E in the fourth column group. Of course, in some examples, the multi-ground wire 18E may also include five ground wires, wherein the fifth ground wire is not electrically connected to the ground terminal of any temperature sensing unit, that is, the fifth ground wire does not short-circuit each corresponding temperature sensing unit in any column group to ground.

[0346] In this embodiment, the multi-purpose signal line 19E includes a first dual-purpose signal line 19-1E, a second dual-purpose signal line 19-2E, a third dual-purpose signal line 19-3E, and a fourth dual-purpose signal line 19-4E, which are respectively configured to correspond one-to-one with the four rows of electrode units 33E of the electrode sheet 13E. Specifically, the four electrode units 33E from electrode unit 33-1E to electrode unit 33-4E are connected in series to the first dual-purpose signal line 19-1E, and the temperature detection units 35E corresponding to each of the four electrode units 33E from electrode unit 33-1E to electrode unit 33-4E are connected in series to the first dual-purpose signal line 19-1E; the four electrode units 33E from electrode unit 33-6E to electrode unit 33-8E are connected in series to the second dual-purpose signal line 19-2E, and the temperature detection units corresponding to each of the four electrode units 33E from electrode unit 33-5E to electrode unit 33-8E are connected in series to the second dual-purpose signal line 19-2E. The 35E electrodes are connected in series to the second dual-purpose signal line 19-2E; the four electrode units 33E, from electrode unit 33-9E to electrode unit 33-12E, are connected in series to the third dual-purpose signal line 19-3E, and the temperature detection units 35E corresponding to each of the four electrode units 33E, from electrode unit 33-9E to electrode unit 33-12E, are connected in series to the third dual-purpose signal line 19-3E; the electrode unit 33-13E is connected to the fourth dual-purpose signal line 19-4E, and the temperature detection unit 35E corresponding to the electrode unit 33-13E is connected to the fourth dual-purpose signal line 19-4E.

[0347] Specifically, in this embodiment, the multiple control switches 54E in the corresponding group of control switches 54E are respectively the first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, the fourth control switch 54-4E, and the fifth control switch 54-5E. The first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E control the closing or opening of the corresponding grounding wire 18E of the same electrode plate 13E. The first control switch 54-1E is used to control the opening or closing of the first grounding wire 18-1E of the corresponding electrode plate 13E, and can then cooperate with the corresponding set of bidirectional switching switches 55E to control the energization and de-energization of the temperature detection units 35E corresponding to the four electrode units 33E (33-1E, 33-5E, 33-9E, and 33-13E) in the first column of the electrode plate 13E; the second control switch 54-2E is used to control the opening or closing of the second grounding wire 18-2E of the electrode plate 13E, and can then cooperate with the corresponding set of bidirectional switching switches 55E to control multiple electrode units (which can be electrode units 33-1E and 33-2E, 33-5E and 33-6E) in the first and second columns of the electrode plate 13E. Temperature detection units 35E corresponding to electrode units 33-9E and 33-10E are energized and de-energized. The third control switch 54-3E is used to control the opening or closing of the third grounding wire 18-3E of the electrode plate 13E, and can cooperate with the corresponding bidirectional switching switch 55E to control the energization and de-energization of temperature detection units 35E corresponding to multiple electrode units (multiple electrode units can be: electrode units 33-1E to 33-3E, electrode units 33-5E to 33-7E, electrode units 33-9E to 33-11E) in the first, second and third columns of the electrode plate 13E. The fourth control switch 54-4E is similar. The fifth control switch 54-5E is not connected to any grounding wire and is not used for signal control.

[0348] Taking the electrical connection between an electrode 13E and an adapter 20E as an example, the multiple bidirectional switching switches 55E in the corresponding group of bidirectional switching switches 55E are respectively the first bidirectional switching switch 55-1E, the second bidirectional switching switch 55-2E, the third bidirectional switching switch 55-3E, and the fourth bidirectional switching switch 55-4E. The first bidirectional switching switch 55-1E, the second bidirectional switching switch 55-2E, the third bidirectional switching switch 55-3E, and the fourth bidirectional switching switch 55-4E control the switching of a corresponding dual-purpose signal line 19E in the multi-channel dual-purpose signal line 19E of the same electrode 13E between transmitting alternating electrical signals and transmitting temperature detection signals. Specifically, the first bidirectional switching switch 55-1E is used to control the switching of the first dual-purpose signal line 19-1E of the corresponding electrode pad 13E between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of each electrode unit 33E in the first row of electrode units 33-1E to 33-4E and the conduction of the signal terminals 35-2E of each temperature detection unit 35E corresponding to the electrode units 33-1E to 33-4E in the first row of electrode units 33-1E to 33-4E. It also cooperates with the corresponding first control switch 54-1E, second control switch 54-2E, third control switch 54-3E, and fourth control switch 54-4E to ensure that the first row of electrode units 33-1E to 33-4E transmits alternating electrical signals to the patient, or that the temperature detection signals detected by one or more combinations of the temperature detection units 35E corresponding to these electrode units 33E are sampled and output to the corresponding ADC unit 5. 2E; The second bidirectional switching switch 55-2E is used to control the switching of the second dual-purpose signal line 19-2E of the corresponding electrode 13E between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each electrode unit 33E to electrode unit 33-8E in the second row of the electrode 13E and the conduction of the signal terminal 35-2E of each temperature detection unit 35E corresponding to electrode unit 33-5E to electrode unit 33-8E in the second row of the electrode 13E, and cooperating with the corresponding first control switch 54-1E, second control switch 54-2E, third control switch 54-3E, and fourth control switch 54-4E, so that the second row of electrode units 33-5E to electrode unit 33-8E transmits alternating electrical signals to the patient or makes the temperature detection signals detected by one or more combinations of the temperature detection units 35E corresponding to these electrode units 33E sampled and output to the corresponding ADC unit 52E.The third bidirectional switching switch 55-3E is used to control the switching of the third dual-purpose signal line 19-3E of the corresponding electrode pad 13E between transmitting alternating electrical signals and transmitting temperature detection signals. This controls the switching between the conduction of each electrode unit 33E in the third row of electrode units 33-9E to 33-12E of the electrode pad 13E and the conduction of the signal terminals 35-2E of the corresponding temperature detection units 35E in the third row of electrode units 33-9E to 33-12E. It also works in conjunction with the corresponding first control switch 54-1E, second control switch 54-2E, third control switch 54-3E, and fourth control switch 54-4E to enable the third row of electrode units 33-9E to 33-12E to transmit alternating electrical signals to the patient or to enable the corresponding temperature detection units 35E to transmit alternating electrical signals to the patient. Temperature detection signals detected by one or more combinations of corresponding combinations in 35E are sampled and output to the corresponding ADC unit 52E; the fourth bidirectional switching switch 55-4E is used to control the switching of the fourth dual-purpose signal line 19-4E of the corresponding electrode 13E between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of electrode units 33-13E in the fourth row of the electrode 13E and the conduction of the signal terminal 35-2E of the temperature detection unit 35E corresponding to the electrode unit 33-13E in the fourth row of the electrode 13E, and cooperating with the corresponding first control switch 54-1E, so that the fourth row of electrode units 33-13E transmits alternating electrical signals to the patient or so that the temperature detection signals detected by the temperature detection unit 35E corresponding to the electrode unit 33E are sampled and output to the corresponding ADC unit 52E.

[0349] Other contents in this embodiment are similar to those in embodiment 3 above, and will not be repeated here.

[0350] Example 7:

[0351] Unlike the tumor electric field therapy system 100E shown in Example 6, the reference... Figure 23 The following describes another tumor electric field therapy system 100F, which is similar in concept to the tumor electric field therapy system 100E described above, except that the number of electrode units 33F contained in each row and column group of each electrode sheet 13E of the tumor electric field therapy system 100F is different.

[0352] Figure 23This is a schematic diagram of the circuit connection between the electrode pad 13F and the adapter 20F of the tumor electric field therapy system 100F. Multiple electrode units 33F are configured into multiple row groups and multiple column groups. In this embodiment, each electrode pad 13F has 13 electrode units 33F. The 13 electrode units 33F are grouped in the circuit connection according to the order 1 to 13. Electrode units 33-1F to 33-13F are divided into four row groups and four column groups, that is, the 13 electrode units 33F are arranged in four rows and four columns in the circuit connection. The first row group includes 4 electrode units 33F, the second to fourth row groups each include 3 electrode units 33F, the first to third column groups each include 4 electrode units 33F, and the fourth column group includes 1 electrode unit 33F.

[0353] The electrode plate 13F includes four grounding wires 18F: a first grounding wire 18-1F, a second grounding wire 18-2F, a third grounding wire 18-3F, and a fourth grounding wire 18-4F. These four grounding wires correspond one-to-one with the four column groups. In some examples, the multiple grounding wires 18F may include five grounding wires, where the fifth grounding wire is not electrically connected to the grounding terminal of any temperature detection unit; that is, the fifth grounding wire does not short-circuit each corresponding temperature detection unit in any column group. The multiple control switches 54F are designated as a first control switch 54-1F, a second control switch 54-2F, a third control switch 54-3F, a fourth control switch 54-4F, and a fifth control switch 54-5F. The first control switch 54-1F, the second control switch 54-2F, the third control switch 54-3F, and the fourth control switch 54-4F each control the closing or opening of the corresponding grounding wire 18F of the same electrode plate 13F. The fifth control switch 54-5F is not connected to any grounding wire and is not used for signal control.

[0354] The multi-channel dual-purpose signal line 19F includes four dual-purpose signal lines: the first dual-purpose signal line 19-1F, the second dual-purpose signal line 19-2F, the third dual-purpose signal line 19-3F, and the fourth dual-purpose signal line 19-4F, each corresponding to one of the four rows of the electrode unit 33F. Multiple bidirectional switches 55F are designated as the first bidirectional switch 55-1F, the second bidirectional switch 55-2F, the third bidirectional switch 55-3F, and the fourth bidirectional switch 55-4F. These switches control the switching of a corresponding dual-purpose signal line 19F within the same electrode sheet 13F between transmitting alternating electrical signals and transmitting temperature detection signals.

[0355] Other contents in this embodiment are similar to those in embodiment 3 above, and will not be repeated here.

[0356] Example 8:

[0357] Unlike the tumor electric field therapy systems 100B, 100C, 100D, 100E, and 100F shown in Examples 3 to 7, the reference... Figure 24 and Figure 25 The following describes another tumor electric field therapy system 100G, whose main concept is the same as the tumor electric field therapy systems 100B, 100C, 100D, 100E or 100F mentioned above. The difference is that each electrode sheet 13G of the tumor electric field therapy system 100G includes 9 electrode units 33G.

[0358] Figure 25 for Figure 24 The diagram shows the circuit connection between the electrode 13G and the adapter 20G of the tumor electric field therapy system 100G.

[0359] Multiple electrode units 33G are configured into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13G has 9 electrode units 33G. The 9 electrode units 33G are arranged in the order of 1 to 9 in the circuit connection. Electrode units 33-1G to 33-9G are divided into three row groups and four column groups. That is, the 9 electrode units 33G are arranged in three rows and four columns in the circuit connection. Each row of the first and second row groups includes 4 electrode units 33G, and the third row group includes 1 electrode unit 33G. The first column group includes 3 electrode units 33G, and each column of the second and fourth column groups includes 2 electrode units 33G.

[0360] The electrode plate 13G includes four grounding wires 18G: a first grounding wire 18-1G, a second grounding wire 18-2G, a third grounding wire 18-3G, and a fourth grounding wire 18-4G. These grounding wires correspond one-to-one with the four columns of the electrode unit 33G. In some examples, the multiple grounding wires 18G may include five grounding wires, where the fifth grounding wire is not electrically connected to the grounding terminal of any temperature detection unit; that is, the fifth grounding wire does not short-circuit each temperature detection unit in any column. The multiple control switches 54G are designated as a first control switch 54-1G, a second control switch 54-2G, a third control switch 54-3G, a fourth control switch 54-4G, and a fifth control switch 54-5G. The first control switch 54-1G, the second control switch 54-2G, the third control switch 54-3G, and the fourth control switch 54-4G each control the closing or opening of the corresponding grounding wire 18G of the same electrode plate 13G. The fifth control switch 54-5G is not connected to any grounding wire and is not used for signal control.

[0361] The multi-channel dual-purpose signal line 19G includes three dual-purpose signal lines: a first dual-purpose signal line 19-1G, a second dual-purpose signal line 19-2G, and a third dual-purpose signal line 19-3G. These three lines correspond one-to-one with the three rows of the electrode unit 33G. In some examples, the multi-channel dual-purpose signal line 19G may also include four dual-purpose signal lines, where the fourth dual-purpose signal line is not electrically connected to the signal terminal of any temperature detection unit. The multiple bidirectional switching switches 55G are designated as a first bidirectional switching switch 55-1G, a second bidirectional switching switch 55-2G, a third bidirectional switching switch 55-3G, and a fourth bidirectional switching switch 55-4G. The first bidirectional switch 55-1G, the second bidirectional switch 55-2G, and the third bidirectional switch 55-3G respectively control the switching of a corresponding dual-purpose signal line 19G in the multi-channel dual-purpose signal line 19G of the same electrode plate 13G between transmitting alternating electrical signals and transmitting temperature detection signals. The fourth bidirectional switch 55-4G is not connected to any dual-purpose signal line and is not used for signal control.

[0362] Other contents in this embodiment are similar to those in Embodiment 1 above, and will not be repeated here.

[0363] Example 9:

[0364] Unlike the tumor electric field therapy system 100G shown in Example 8, the reference... Figure 26The following describes another tumor electric field therapy system 100H, whose main concept is the same as the tumor electric field therapy system 100G described above. The difference is that the number of electrode units 33H contained in each row and column group of each electrode sheet 13H in the circuit connection of the tumor electric field therapy system 100H is different.

[0365] Figure 26 The diagram shows the circuit connection between the electrode 13H and the adapter 20H of the tumor electric field therapy system 100H.

[0366] Multiple electrode units 33H are configured into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13H is provided with 9 electrode units 33H. The 9 electrode units 33H are arranged in the order of 1 to 9 in the circuit connection. Electrode units 33-1H to electrode units 33-9H are divided into three row groups and three column groups. That is, the 9 electrode units 33H are arranged in three rows and three columns in the circuit connection. Each row group includes 3 electrode units 33H, and each column group includes 3 electrode units 33H.

[0367] The electrode plate 13H includes three grounding wires 18H: a first grounding wire 18-1H, a second grounding wire 18-2H, and a third grounding wire 18-3H. These three grounding wires correspond one-to-one with the three column groups. In some examples, the multiple grounding wires 18H may include four or five grounding wires, where the fourth and / or fifth grounding wires are not electrically connected to the grounding terminal of any temperature detection unit; that is, the fourth and / or fifth grounding wires do not short-circuit each corresponding temperature detection unit in any column group. The multiple control switches 54H are designated as a first control switch 54-1H, a second control switch 54-2H, a third control switch 54-3H, a fourth control switch 54-4H, and a fifth control switch 54-5H. The first control switch 54-1H, the second control switch 54-2H, and the third control switch 54-3H each control the closing or opening of the corresponding grounding wire 18H of the same electrode plate 13H. The fourth control switch 54-4H and the fifth control switch 54-5H are not connected to any grounding wire, and the fourth control switch 54-4H and the fifth control switch 54-5H are not used for signal control.

[0368] The multi-channel dual-purpose signal line 19H includes three dual-purpose signal lines: a first dual-purpose signal line 19-1H, a second dual-purpose signal line 19-2H, and a third dual-purpose signal line 19-3H. These three lines correspond one-to-one with the three rows of the electrode unit 33H. In some examples, the multi-channel dual-purpose signal line 19H may also include four dual-purpose signal lines, where the fourth dual-purpose signal line is not electrically connected to the signal terminal of any temperature detection unit. The multiple bidirectional switching switches 55H are designated as a first bidirectional switching switch 55-1H, a second bidirectional switching switch 55-2H, a third bidirectional switching switch 55-3H, and a fourth bidirectional switching switch 55-4H. The first bidirectional switch 55-1H, the second bidirectional switch 55-2H, and the third bidirectional switch 55-3H respectively control the switching of a corresponding dual-purpose signal line 19H in the multi-channel dual-purpose signal line 19H of the same electrode sheet 13H between transmitting alternating electrical signals and transmitting temperature detection signals. The fourth bidirectional switch 55-4H is not connected to any dual-purpose signal line and is not used for signal control.

[0369] Other contents in this embodiment are similar to those in embodiment 8 above, and will not be repeated here.

[0370] Example 10:

[0371] The main concept of the aforementioned tumor electric field therapy system 100 is that both the adapter 20 and the electric field generator 30 are equipped with an alternating power supply line 57 to control the synchronous change of the alternating electrical signal of all electrode units 33 on an electrode plate 13, such as voltage or current rising or falling simultaneously. However, it cannot simultaneously apply different alternating electrical signals, such as different voltages or currents, to electrode units 33 in different rows. (Reference) Figures 27 to 31 The following describes another tumor electric field therapy system 100', whose main concept is the same as the tumor electric field therapy system 100 described above. The difference is that: in the adapter 20' and electric field generator 30' of this tumor electric field therapy system 100', each row of electrode units 33' on the corresponding electrode plates 13' is provided with a corresponding alternating power supply line 57', so that different alternating electrical signals, such as different voltages or currents, can be applied to different row of electrode units 33' at the same time.

[0372] Figure 28 This is a schematic diagram of the circuit connection between an electrode 13', an adapter 20', and an electric field generator 30' in another tumor electric field therapy system 100' according to an embodiment of this application. Figure 29The following is a schematic diagram of another electrode unit 33' in an embodiment of this application. The tumor electric field therapy system 100' includes: at least one pair of electrode plates 13', an adapter 20' connected to the electrode plates 13', and an electric field generator 30' connected to the adapter 20'.

[0373] The specific structure of electrode 13' is the same as that of electrode 13 described above, and will not be repeated here.

[0374] The specific construction of adapter 20' is similar to that of adapter 20 described above, except that: (Refer to...) Figure 28 and Figure 30 Each electrode 13' in the adapter 20' is equipped with four alternating power lines 57'. The four alternating power lines 57' correspond one-to-one with the four row group electrode units 33' of each electrode 13'. Each electrode 13' is equipped with a corresponding bidirectional switching switch 55' and a grounding switch 54'. Both ends of the bidirectional switching switch 55' are electrically connected to a separate AC power line 57', so that the tumor electric field therapy system 100' can apply different alternating electrical signals, such as different voltages or currents, to different row group electrode units 33' in each electrode 13' as needed.

[0375] The specific structure of the electric field generator 30' is similar to that of the electric field generator 30 described above, except that: (Refer to...) Figure 28 and Figure 31 Each AC power supply line 57' between the AC signal generator 39' and the adapter 20' is equipped with a power supply switch 40' to control the switching on and off of the AC signal for each row of electrode units 33' of each electrode piece 13'.

[0376] Specifically, refer to Figure 28 and Figure 30As shown, the adapter 20' includes: a first controller 51', multiple ADC units 52' connected to the first controller 51', multiple voltage-reducing resistors 53' and multiple control switches 54' corresponding to each of the multiple ADC units 52', multiple bidirectional switching switches 55' corresponding to each of the multiple ADC units 52', a first communication unit 56', multiple alternating power lines 57' corresponding to each of the bidirectional switching switches 55', and a first power module 58' connected to the first communication unit 56', the first controller 51', and the multiple ADC units 52'. The first power module 58' provides DC power VCC to each electronic component of the adapter 20'. The adapter 20' also includes multiple circuit lines (unlabeled), which are electrically connected to multiple grounding lines 18' and multiple dual-purpose signal lines 19' in the substrate 31' of the corresponding electrode plates 13' through the first cables 15' of the corresponding electrode plates 13'. The multiple circuit lines (unlabeled) include multiple alternating power supply lines 57' that transmit alternating electrical signals to the corresponding electrode plates 13' and are electrically connected to the multi-purpose signal lines 19' in the substrate 31' of the corresponding electrode plate 13'; multiple circuit lines (unlabeled) that are electrically connected one-to-one with the multi-purpose signal lines 19' in the substrate 31' of the corresponding electrode plates 13' and are used to power each temperature detection unit 35' of the electrode plate 13' or transmit the temperature detection signal of the electrode plate 13'; and multiple circuit lines (unlabeled) that are electrically connected one-to-one with the multiple grounding lines 18' in the substrate 31' of the corresponding electrode plates 13'. The number L of circuit lines electrically connecting adapter 20' to one electrode piece 13' is equal to the sum of the number of rows and columns of electrode units 33' of electrode piece 13'; the number H of circuit lines electrically connecting adapter 20' to X electrode pieces 13' is equal to X times the number of circuit lines electrically connecting it to a single electrode piece 13', i.e., H = XL = X × (M + N). The number of groups of control switches 54' and bidirectional switching switches 55' is related to the number of electrode pieces 13'. The number of groups of control switches 54' is the same as the number of groups of bidirectional switching switches 55', and not less than the number of electrode pieces 13'. Optionally, the number of groups of control switches 54' and bidirectional switching switches 55' is the same as the number of electrode pieces 13'.

[0377] For example, each group of control switches 54' has multiple control switches 54', which are respectively connected to the adapter 20' and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multiple grounding wires 18' of a corresponding electrode piece 13', and are configured to control the on or off of the multiple grounding wires 18'. The circuit lines (unlabeled) that are each electrically connected to the multiple grounding wires 18' of the electrode piece 13' are grounded at the end closest to the control switch 54'. The number of control switches 54' in each group of control switches 54' is related to the number of grounding wires 18' of the corresponding electrode piece 13' substrate 31', and in this embodiment, the two are equal. Figure 28As shown, in this embodiment, the multiple control switches 54' in each group of control switches 54' are respectively the first control switch 54-1', the second control switch 54-2', the third control switch 54-3', the fourth control switch 54-4', and the fifth control switch 54-5'. The multiple control switches 54' in the same group each control the closing or opening of the corresponding grounding wire 18' of the same electrode plate 13'. The first control switch 54-1' is used to control the opening or closing of the first grounding wire 18-1' of the corresponding electrode plate 13', and can then cooperate with the corresponding set of bidirectional switching switches 55' to control the energization and de-energization of the temperature detection units 35' corresponding to the four electrode units 33' in the first column of the electrode plate 13': electrode unit 33-1', electrode unit 33-6', electrode unit 33-11', and electrode unit 33-16'. The second control switch 54-2' is used to control the opening or closing of the second grounding wire 18-2' of the electrode plate 13', and can then cooperate with the corresponding set of bidirectional switching switches 55' to control multiple electrode units in the first and second columns of the electrode plate 13' (the multiple electrode units can be: electrode unit 33-1' and electrode unit 33-2', electrode unit 33-6' and electrode unit 33-7', electrode unit 33-16', and electrode unit 33-17'). The temperature detection units 35' corresponding to electrode units 33-11', 33-12', 33-16', and 33-17' are energized and de-energized. The third control switch 54-3' is used to control the closing or opening of the third grounding wire 18-3' of the electrode plate 13', and can cooperate with the corresponding bidirectional switching switches 55' to control the energization and de-energization of the temperature detection units 35' corresponding to multiple electrode units (multiple electrode units can be: electrode units 33-1' to 33-3', electrode units 33-6' to 33-8', electrode units 33-11' to 33-13', and electrode units 33-16' to 33-18') in the first, second, and third columns of the electrode plate 13'. The fourth control switch 54-4' and the fifth control switch 54-5' work similarly. The control switches 54' can be mechanical switches, such as relays. The control switch 54' can also be an electronic switch, and each control switch 54' can be opened and closed by an additional first controller 51'.

[0378] In this embodiment, all sets of control switches 54' are electronic switches. The first controller 51' is communicatively connected to the multiple sets of control switches 54', and is used to sequentially and cyclically control the opening and closing states of multiple control switches 54' in each set, thereby sequentially and individually activating each grounding wire 18' of the corresponding electrode 13' and coordinating with the switching of the corresponding bidirectional switching switch 55' to collect the patient's body surface temperature detected by all temperature detection units 35' on the electrode 13'. The number of control switches 54' in each set is not less than the number of grounding wires 18' on the substrate 31' of the corresponding electrode 13'. In this embodiment, the number of control switches 54' in each set is the same as the number of grounding wires 18' on the corresponding electrode 13'.

[0379] Each group of bidirectional switching switches 55' has multiple bidirectional switching switches 55'. The multiple bidirectional switching switches 55' in each group are respectively connected to the adapter 20' and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multi-purpose signal lines 19' of the corresponding electrode piece 13'. The number of bidirectional switching switches 55' in each group of bidirectional switching switches 55' is related to the number of multi-purpose signal lines 19' of the substrate 31' of the corresponding electrode piece 13', which is greater than or equal to the number of multi-purpose signal lines 19' of the substrate 31' of the corresponding electrode piece 13'. In this embodiment, the two are equal. Each bidirectional switch 55' has two ends labeled 1 and 2. The ends of multiple bidirectional switches 55' in the same group are electrically connected to the corresponding detection channels of the multiple detection channels of the corresponding group of ADC units 52' through temperature sampling points (unlabeled). The ends of each bidirectional switch 55' in the same group are electrically connected to the corresponding different alternating power lines 57' and are configured to control the multiplexed signal line 19' to connect to the corresponding different alternating power lines 57' to transmit alternating electrical signals or to connect to the corresponding detection channels of the corresponding group of ADC units 52' to receive the temperature detection signals output by the temperature detection unit 35'.

[0380] like Figure 28As shown, taking the electrical connection of one electrode piece 13' with the adapter 20' as an example, in this embodiment with 20 electrode units 33', the multiple bidirectional switching switches 55' in each group of bidirectional switching switches 55' are respectively the first bidirectional switching switch 55-1', the second bidirectional switching switch 55-2', the third bidirectional switching switch 55-3', and the fourth bidirectional switching switch 55-4'. The multiple bidirectional switching switches 55' in the same group each control the switching of a corresponding dual-purpose signal line 19' in the same electrode piece 13' between transmitting alternating electrical signals and transmitting temperature detection signals. Specifically, the first bidirectional switching switch 55-1' is used to control the switching between the alternating electrical signal output from the alternating power supply line 57-1' and the temperature detection signal of the first dual-purpose signal line 19-1' of the corresponding electrode 13', thereby controlling the switching between the conduction of each electrode unit 33' from electrode unit 33-1' to electrode unit 33-5' in the first row of the electrode 13' and the conduction of the signal terminal 35-2' of each temperature detection unit 35' corresponding to electrode unit 33-1' to electrode unit 33-5' in the first row of the electrode 13', and the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', and fourth control switch 54-4'. The fifth control switch 54-5' works in conjunction with the first row of electrode units 33-1' to 33-5' to transmit individual alternating electrical signals to the patient, or to sample and output the temperature detection signals detected by one or more combinations of temperature detection units 35' corresponding to these electrode units 33' to the corresponding ADC unit 52'. The second bidirectional switching switch 55-2' controls the switching between the second dual-purpose signal line 19-2' of the corresponding electrode piece 13' and the alternating electrical signal output from the alternating power line 57-2', thereby controlling the switching between the conduction of each electrode unit 33' in the second row of electrode units 33-6' to 33-10' and the conduction of the signal terminals 35-2' of each temperature detection unit 35' corresponding to the electrode units 33-6' to 33-10' in the second row of electrode units 13', and the switching between the two, and the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', and fourth control switch 54-4'. The fifth control switch 54-5' is engaged to enable the second row of electrode units 33-6' to 33-10' to transmit individual alternating electrical signals to the patient or to enable the temperature detection signals detected by one or more combinations of the corresponding temperature detection units 35' of these electrode units 33' to be sampled and output to the corresponding ADC unit 52'.The third bidirectional switching switch 55-3' is used to control the switching of the third dual-purpose signal line 19-3' of the corresponding electrode piece 13' between the alternating electrical signal output from the alternating power supply line 57-3' and the temperature detection signal, thereby controlling the conduction of each electrode unit 33' in the third row group of the electrode piece 13' and the conduction of the signal terminal 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-11' to the electrode unit 33-15' in the third row group. This switching is also connected to the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', and fourth control switch 54-4'. The fifth control switch 54-5' is used to enable the third row of electrode units 33-11' to 33-15' to transmit individual alternating electrical signals to the patient, or to enable the temperature detection signals detected by one or more combinations of the corresponding temperature detection units 35' of these electrode units 33' to be sampled and output to the corresponding ADC unit 52'; the fourth bidirectional switching switch 55-4' is used to control the fourth dual-purpose signal line 19-4' of the corresponding electrode piece 13' to transmit alternating power from the alternating power line 57-4'. The switching between the signal and the transmitted temperature detection signal controls the conduction of each electrode unit 33' in the fourth row of electrode units 33-16' to 33-20' in the electrode pad 13' and the conduction of the signal terminals 35-2' of the corresponding temperature detection units 35' in the fourth row of electrode units 33-16' to 33-20'. This switching, in conjunction with the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', fourth control switch 54-4', and fifth control switch 54-5', allows the fourth row of electrode units 33-16' to 33-20' to transmit individual alternating electrical signals to the patient, or allows the temperature detection signals detected by one or more combinations of the corresponding temperature detection units 35' to be sampled and output to the corresponding ADC unit 52'. The aforementioned bidirectional switching switch 55' can be a mechanical switch, such as a relay. The bidirectional switch 55' can also be an electronic switch, and each bidirectional switch 55' can be switched via an additional first controller 51'.

[0381] In this embodiment, all of the multiple sets of bidirectional switching switches 55' are electronic switches. The first controller 51' is communicatively connected to the multiple sets of bidirectional switching switches 55' and is used to control the switching of multiple bidirectional switching switches 55' in each set between their respective terminals 1 and 2, and to cooperate with the closing or opening of the corresponding control switch 54' to continuously monitor the temperature of the patient's body surface detected by all temperature detection units 35' on the electrode pad 13' or to transmit alternating electrical signals to the patient.

[0382] In this embodiment, each ADC unit 52' is electrically connected to one end of multiple bidirectional switching switches 55' in the corresponding group via multiple circuit lines (unlabeled) within the adapter 20', and is configured to receive temperature detection signals transmitted from the multi-purpose signal lines 19' of the corresponding electrode 13', and convert the temperature detection signals from analog signals to digital temperature signals. Each ADC unit 52' includes multiple detection channels A, B, C, and D, each detection channel A, B, C, and D being connected to one corresponding dual-purpose signal line 19' in the multi-purpose signal lines 19' via the corresponding bidirectional switching switch 55'. Figure 28 As shown, each ADC unit 52' contains four detection channels A, B, C, and D, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. The first detection channel A is connected to the first dual-purpose signal line 19-1' through one end of the first bidirectional switch 55-1'; the second detection channel B is connected to the second dual-purpose signal line 19-2' through one end of the second bidirectional switch 55-2'; the third detection channel C is connected to the third dual-purpose signal line 19-3' through one end of the third bidirectional switch 55-3'; and the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4' through one end of the fourth bidirectional switch 55-4'. Each detection channel A, B, C, and D is used to receive the temperature detection signal collected by the temperature detection unit 35' corresponding to the electrode unit 33' connected to the corresponding dual-purpose signal line 19'. In addition, each detection channel A, B, C, and D is connected to a first power supply module 58' via a corresponding voltage divider resistor 53' within the adapter 20'. The first power supply module 58' provides DC power to the detection channel A, B, C, and D.

[0383] In this embodiment, the first communication unit 56' is configured to acquire digital temperature signals output by multiple ADC units 52' and send the digital temperature signals to the electric field generator 30'. The electric field generator 30' is also configured to control and adjust the voltage of the alternating electrical signal provided to the multiple electrode units 33' of the electrode sheet 13' according to the received digital temperature signals. For example, when any of the received digital temperature signals exceeds a preset threshold, it indicates that the temperature detected by the temperature detection unit 35' corresponding to at least one electrode unit 33' in the electrode sheet 13' exceeds the preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage of the alternating electrical signal output by the electric field generator 30' can be appropriately reduced or stopped to avoid the electrode units 33' of the electrode sheet 13' from becoming too hot when the alternating electrical signal is applied, causing low-temperature burns to the patient's skin. The aforementioned preset threshold temperature and preset threshold can be determined according to human safety thresholds. The first communication unit 56' is controlled by the first controller 51' and serially transmits the digital temperature signals converted by the multiple ADC units 52'. In this embodiment, the preset threshold temperature can be a value within the range of 36℃-45℃.

[0384] refer to Figure 28In this embodiment, the first power module 58' is electrically connected to the second power module 32' of the electric field generator 30', and is configured to supply power to the first controller 51', multiple ADC units 52', and the first communication unit 56' of the adapter 20'. A first connector 60' is provided between each electrode 13' and the adapter 20', and the first connector 60' is adapted to connect the corresponding electrode 13' to the adapter 20'. A second connector 70' is provided between the adapter 20' and the electric field generator 30', and the second connector 70' is adapted to connect the electric field generator 30' to the adapter 20'. The adapter 20' also includes a second cable 25' connected to the second connector 70'. The second connector 70' includes a second plug 71' located at the end of the second cable 25' away from the first controller 51' and a second socket 72' located on the electric field generator 30'. The second plug 71' and the second socket 72' are push-button spring connectors, meaning the second connector 70' connects the adapter 20' and the electric field generator 30' using a connector. Each first connector 60', such as X1, Y1, X2, and Y2, is connected to the second connector 70' via a corresponding four-way AC power line 57'. The first connectors 60', such as X1, Y1, X2, and Y2, are also connected to a corresponding set of control switches 54' and a corresponding set of ADC units 52'. Each first connector 60' is connected to the second connector 70' and the corresponding set of ADC units 52' via a corresponding set of bidirectional switching switches 55'. The second cable 25' has eight wires, including four five-core wires 1 to 4 that are electrically connected to the corresponding four AC power lines 57' and used to transmit different AC signals; one wire 5 that is electrically connected to the data receiving line RX' of the first communication unit 56'; one wire 6 that is electrically connected to the data transmitting line TX' of the first communication unit 56'; one wire 7 that is electrically connected to the VCC power line of the first power module 58'; and one wire 8 that is electrically connected to the GND line of the first power module 58'. The second connector 70' is connected to the first communication unit 56' via the data receiving line RX' and the data transmitting line TX'. The VCC pin of the second connector 70' is connected to the VVC power line of the first power module 58', and the GND pin of the second connector 70' is connected to the GND line of the first power module 58' and grounded. The VCC pin of the second connector 70' is also connected to the corresponding group of voltage regulators 53' and the corresponding group of ADC units 52' via the VCC power line of the first power module 58'.

[0385] refer to Figure 28 and Figure 31The electric field generator 30' includes: a second power module 32', a second controller 37', an AC signal generator 39', a second communication unit 38', and multiple sets of power switches 40'. The VCC pin of the second connector 70' is also electrically connected to the VCC power line of the second power module 32', and the GND pin of the second connector 70' is grounded through the GND line of the second power module 32'. The second power module 32' is also connected to and supplies power to the second controller 37' and the AC signal generator 39', respectively. The second communication unit 38' is electrically connected to the wire 5 of the second connector 70' through its data receiving line RX' and to the wire 6 of the second connector 70' through its data transmitting line TX', thereby enabling information exchange between the electric field generator 30' and the adapter 20'. The second controller 37' is also electrically connected to the second communication unit 38', the AC signal generator 39', and multiple sets of power supply switches 40'. The second controller 37' is configured to control the opening and closing of each power supply switch 40' in the multiple sets of power supply switches 40' and adjust the relevant parameters of different alternating electrical signals applied by the AC signal generator 39' based on the relevant digital temperature signals received from the adapter 20' by the second communication unit 38'. The AC signal generator 39 is electrically connected to the second connector 70' via wires 1 to 4 that transmit different alternating electrical signals through the multiple sets of power supply switches 40'. Each set of power supply switches 40' includes multiple power supply switches 40', and the multiple sets of power supply switches 40' are arranged one-to-one with multiple electrode plates 13'. Each group of power supply switches 40' is electrically connected to a corresponding four-core wire 1, 2, 3, 4 in the second connector 70' via a four-core AC power cable 41-1', 41-2', 41-3', 41-4', and then electrically connected to the corresponding electrode plate 13' via the corresponding four-core wire 1, 2, 3, 4 in the second connector 70', so as to transmit different alternating electrical signals to each row of electrode units 33' in each electrode plate 13. The AC signal generator 39' is electrically connected to multiple groups of power supply switches 40' via a five-core AC power cable 41'. Specifically, the number of groups of power supply switches 40' in the electric field generator 30' is related to the number of electrode plates 13'. In this embodiment, the number of groups of power supply switches 40' is equal to the number of electrode plates 13', both being four. The number of multiple power supply switches 40' in each group of power supply switches 40' is related to the number of rows of the corresponding electrode plates 13'. In this embodiment,The number of each group of power supply switches 40' is equal to the number of rows of the corresponding electrode plates 13', and there are 4 of each group. The multiple groups of power supply switches 40' include a first group of power supply switches 40-1', a second group of power supply switches 40-2', a third group of power supply switches 40-3', and a fourth group of power supply switches 40-4', which are electrically connected to the four-core wires 1 to 4 of the second connector 70' respectively. One end of the first power supply switch 40-1' is electrically connected to the AC signal generator 39' via the four-core AC power line (unlabeled) of the electric field generator 30'. The other end is electrically connected to the corresponding four-core wire 1 for transmitting alternating electrical signals in the second connector 70' via a four-core AC power line 41-1', and then electrically connected to the four-way alternating power line 57' at port X1' of the adapter 20' via the four-core wire 1 of the second connector 70'. The four-way alternating power line 57' at port X1' of the adapter 20' is electrically connected to the first connector 60'. The first connection at port X1 of the adapter 20'... The device 60' is electrically connected to the corresponding electrode 13' to control whether the AC signal generator 39' supplies different alternating electrical signals to the electrode units 33' in the four rows of the four alternating power lines 57' in the electrode 13' electrically connected to the port X1 of the adapter 20'; one end of the second power supply switch 40-2' is electrically connected to the AC signal generator 39' through the four-core AC power line (unlabeled) of the electric field generator 30', and the other end is electrically connected to the corresponding four-core wire 2 for transmitting alternating electrical signals in the second connector 70' through a four-core AC power line 41-2' and through the second connector 70'. The four-core wire 2 is electrically connected to the four-channel AC power line 57' located at port Y1' of adapter 20'; the four-channel AC power line 57' located at port Y1' of adapter 20' is electrically connected to the first connector 60'; the first connector 60' located at port Y1' of adapter 20' is electrically connected to the corresponding electrode piece 13', so as to control whether the AC signal generator 39' transmits different AC electrical signals to the electrode unit 33' in the four rows of the electrode piece 13' electrically connected to port Y1' of adapter 20' corresponding to the four-channel AC power line 57'; one end of the third group power supply switch 40-3' is connected through... The four-core AC power cable (unlabeled) of the electric field generator 30' is electrically connected to the AC signal generator 39'. The other end is electrically connected to the corresponding four-core wire 3 for transmitting alternating electrical signals in the second connector 70' via a four-core AC power cable 41-3'. It is also electrically connected to the four-channel alternating power cable 57' located at port X2' of the adapter 20' via the four-core wire 3 of the second connector 70'. The four-channel alternating power cable 57' located at port X2' of the adapter 20' is electrically connected to the first connector 60'. The first connector 60' located at port X2' of the adapter 20' is electrically connected to the corresponding electrode plate 13'.The AC signal generator 39' controls whether it supplies different alternating electrical signals to the electrode units 33' in the four rows of the four alternating power lines 57' in the electrode plate 13' electrically connected to the port X2' of the adapter 20'; one end of the fourth power supply switch 40-4' is electrically connected to the AC signal generator 39' through the four-core AC power line (unlabeled) of the electric field generator 30', and the other end is electrically connected to the corresponding four-core wire 4 for transmitting alternating electrical signals in the second connector 70' through a four-core AC power line 41-4' and through the second connector 70. The four-core wire 4 of the adapter 20 is electrically connected to the four alternating power lines 57' located at port Y2'. The four alternating power lines 57' located at port Y2' of the adapter 20 are electrically connected to the first connector 60'. The first connector 60' located at port Y2' of the adapter 20 is electrically connected to the corresponding electrode plate 13', so as to control whether the AC signal generator 39' transmits different alternating electrical signals to the electrode units 33' in the four rows of the electrode plate 13' corresponding to the four alternating power lines 57', which are electrically connected to port Y1' of the adapter 20'.

[0386] The following will refer to Figures 28 to 31 The working principle of the tumor electric field therapy system 100' in this embodiment is described in detail.

[0387] It should be noted that the working principle of temperature acquisition in the tumor electric field therapy system 100' is the same as that of temperature acquisition in the tumor electric field therapy system 100, and will not be repeated here.

[0388] The working principle of applying alternating electrical signals to the tumor electric field therapy system 100' is similar to that of applying alternating electrical signals to the tumor electric field therapy system 100. The difference is that this embodiment can apply different alternating electrical signals to electrode units 33' located in different rows at the same time, which is more flexible.

[0389] Specifically, when it is necessary to apply alternating electrical signals to each electrode unit 33' of a certain electrode plate 13', the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls each of the multiple bidirectional switching switches 55' of a set of bidirectional switching switches 55' electrically connected to the electrode plate 13' to turn on two ends and turn off one end. At the same time, it controls all the control switches 54' of the corresponding set of control switches 54' to turn off, and controls a set of power supply switches 40' electrically connected to the electrode plate 13' to turn on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply different alternating electrical signals to each row of electrode units 33' of the electrode plate 13' through different alternating power lines 57', and the magnitude of the voltage or current of the different alternating electrical signals applied can be adjusted. That is, the switching unit (unlabeled) is configured to switch the dual-use signal line 19 corresponding to at least two row groups to different alternating power lines 57', so that each electrode unit 33 of each row group is applied with different alternating electrical signals based on different alternating power lines 57'.

[0390] It should be noted that in other embodiments, a set of bidirectional switching switches 55' electrically connected to a certain electrode piece 13' can also be controlled by the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' to apply different alternating electrical signals to some electrode units 33' of the electrode piece 13' at the same time period. For example, the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls the first bidirectional switch 55-1' of a set of bidirectional switches 55' electrically connected to the electrode 13' to turn on at both ends and turn off at the other end. At the same time, it controls all the control switches 54' in the corresponding set of control switches 54' to turn off, and controls the one power supply switch 40' of a set of power supply switches 40' electrically connected to the electrode 13' and corresponding to the first bidirectional switch 55-1' to turn on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply an alternating electrical signal to the first row of electrode units 33-1' to 33-5' of the electrode 13' through the corresponding alternating power supply line 57', and the magnitude of the applied alternating electrical signal voltage or current is adjustable. It should be noted that in some other embodiments, different alternating electrical signals can be applied to the two or three rows of electrode units 33' simultaneously within the same time period, which will not be elaborated here.

[0391] It should be noted that in this embodiment, the control switch 54', which is electrically connected to each of the multiple grounding lines 18' of the electrode plate 13', and the bidirectional switching switch 55', which is electrically connected to each of the multiple dual-purpose signal lines 19' of the electrode plate 13', are both located in the adapter 20'. However, in other embodiments, the control switch 54', which is electrically connected to the grounding line 18', and the bidirectional switching switch 55', which is electrically connected to the dual-purpose signal lines 19', may also be located on the electrode plate 13' or in the electric field generator 30', which will not be elaborated further here. In addition, the ADC unit 52' located in the adapter 20' may also be located in the electric field generator 30' and directly controlled by the second controller 37'.

[0392] The tumor electric field therapy system 100' of this application can achieve real-time and comprehensive temperature monitoring of all electrode units 33' on the electrode sheet 13' without increasing the weight of the electrode sheet 13' or the number of wire cores in the first cable 15' electrically connected to the electrode sheet 13'. Based on the obtained temperature detection signals, it can determine whether the electrode sheet 13' is qualified; or it can determine whether the temperature detection unit 35' of the electrode sheet 13' is faulty or abnormal, and determine whether the electrode sheet 13' needs to be replaced based on the number of faulty or abnormal temperature detection units 35'; or, if the electrode sheet 13' is qualified, it can identify the electrode sheet type based on the obtained temperature detection signals; or, if the electrode sheet 13' is qualified, it can determine whether the electrode units 33' of the electrode sheet 13' are overheated based on the obtained temperature detection signals, and thus control the alternating electrical signal applied to the electrode sheet 13' or the corresponding electrode units 33' of the electrode sheet 13', avoiding low-temperature burns to the patient's skin during tumor treatment through the electrode sheet 13'. Furthermore, the substrate 31' of the electrode sheet 13' of this application is electrically connected to the signal terminal 35-2' of the same electrode unit 33' and its corresponding temperature detection unit 35' simultaneously via the same dual-purpose signal line 19'. This allows for the transmission of both alternating current signals and DC signals for temperature signal acquisition, along with the acquired temperature detection signals, via the dual-purpose signal line 19'. Simultaneously, it significantly reduces the number of conductive traces (grounding line 18', dual-purpose signal line 19') on the substrate 31', lowering the wiring complexity, simplifying the manufacturing process, reducing the weight of the substrate 31', and lowering manufacturing costs. The electrode sheet 13' of this application can also switch between applying alternating current signals for tumor treatment and transmitting DC signals for temperature acquisition and the acquired temperature detection signals through a combination of control switch 54' electrically connected to its grounding line 18' and bidirectional switching switch 55' electrically connected to the dual-purpose signal line 19'.

[0393] Specifically, when it is necessary to apply alternating electrical signals to the patient through each electrode unit 33' of a certain electrode pad 13', the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls all the control switches 54' in a set of control switches 54' corresponding to the electrode pad 13' to be disconnected, and at the same time controls all the bidirectional switching switches 55' in a set of bidirectional switching switches 55' corresponding to the electrode pad 13' to be switched to their respective 2 ends, so that 1 end of these bidirectional switching switches 55' is completely disconnected and 2 ends are completely connected, so that each dual-purpose signal line 19' of the electrode pad 13' is electrically connected to the adapter 20' and the corresponding multi-channel alternating power supply line 57' of the electrode pad 13', thereby transmitting the same or different alternating electrical signals to each electrode unit 33' of the electrode pad 13'. When the temperature detection signals of the temperature detection units 35' corresponding to all electrode units 33' of the detected electrode 13' are much lower than the preset temperature threshold stored in the electric field generator 30' or the adapter 20', the electric field generator 30' controls the AC signal generator 39 to continue generating alternating electrical signals with increased voltage or current amplitude, or with constant voltage or current amplitude, through its second controller 37'. These signals are then transmitted to the corresponding counter electrode 13' via the corresponding multi-channel alternating power line 57' of the adapter 20', so that the counter electrode 13' continues to receive alternating electrical signals. When the temperature detection signals of the temperature detection units 35' corresponding to all electrode units 33' of the detected electrode 13' are lower than but close to the preset temperature threshold stored in the electric field generator 30' or the adapter 20', the electric field generator 30' can reduce the voltage or current of the alternating electrical signals generated by the AC signal generator 39' through the second controller 37'. The alternating current applied to the electrode 13' is reduced by the current applied to the electrode 13'. When the temperature detection signal of the temperature detection unit 35' corresponding to the electrode unit 33' of a certain electrode 13' is detected to be greater than the preset temperature threshold, the electric field generator 30' controls a set of power supply switches 40' electrically connected to the electrode 13' to disconnect through the second controller 37', so as to stop applying the alternating current signal to the electrode 13'. Alternatively, the second controller 37' of the electric field generator 30' or the first controller 51' of the adapter 20' controls all the bidirectional switching switches 55' of a set of bidirectional switching switches 55' electrically connected to the electrode 13' to switch from their 2 ends to their 1 ends, that is, controls all the bidirectional switching switches 55' of a set of bidirectional switching switches 55' electrically connected to the electrode 13' to have their 1 ends fully turned on and their 2 ends fully turned off, thereby stopping the application of the alternating current signal to the electrode 13'.Alternatively, when the temperature detection signal of a temperature detection unit 35' corresponding to an electrode unit 33' of a certain electrode plate 13' is detected to be greater than a preset temperature threshold, the second controller 37' of the electric field generator 30' controls a set of power supply switches 40' electrically connected to the electrode plate 13' to continue to conduct, and the second controller 37' of the electric field generator 30' or the first controller 51' of the adapter 20' controls a bidirectional switching switch 55' electrically connected to the electrode unit 33' of the electrode plate 13' to switch from its 2nd end to its 1st end, and the second controller 37' of the electric field generator 30' or the first controller 51' of the adapter 20' simultaneously controls the electrode unit 33' whose temperature detection signal does not exceed the preset temperature threshold and is in a different row from the electrode unit 33' whose temperature detection signal exceeds the preset temperature threshold. The remaining bidirectional switching switches 55' connected to electrode 33' remain electrically connected to their respective terminals to stop applying alternating electrical signals to all electrode units 33' in the row where the temperature detection signal of electrode unit 33' exceeds a preset temperature threshold. Alternating electrical signals continue to be applied to the remaining rows of electrode units 33' where the temperature detection signal does not exceed the preset temperature threshold. The alternating electrical signals applied to the remaining rows of electrode units 33' can be the same or different. For example, rows whose temperature detection signals do not exceed the preset temperature threshold but are closer to it are treated with a reduced voltage or current amplitude, while rows whose temperature detection signals do not exceed the preset temperature threshold but are farther from it are treated with a increased voltage or current amplitude. This achieves a method for controlling the application of alternating electrical signals based on temperature detection signals in the tumor electric field therapy system 100'.

[0394] It should be noted that the alternating electrical signal application method, electrode temperature detection method, electrode temperature anomaly detection method, control method, and electrode type identification method of the tumor electric field therapy system 100' in this embodiment are similar to the control method of the aforementioned tumor electric field therapy system 100. The difference is that the tumor electric field therapy system 100' in this embodiment can also apply different alternating electrical signals, such as different voltages or currents, to the electrode units 33' in each region (i.e., each row group) simultaneously according to the temperature of the electrode units 33' in each region, to prevent the electrode units 33' in the corresponding region from exceeding the preset temperature threshold, so as to apply the electric field continuously for a long time and improve the treatment effect.

[0395] Specifically, the tumor electric field therapy system 100' of this embodiment can adopt... Figure 8 The electrode temperature detection method shown determines the temperature at each electrode unit 33' in electrode 13'. For details, please refer to [reference needed]. Figure 8 This will not be elaborated upon here.

[0396] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 9 The method for detecting abnormal temperature of electrode 13' shown can be used to determine whether there is an abnormality. Please refer to the following for details. Figure 9 This will not be elaborated upon here.

[0397] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 32 The control method of the tumor electric field therapy system shown controls the intensity of the alternating electrical signal applied to the electrode unit 33', specifically including the following steps:

[0398] Step 210': Control the switching unit so that the dual-use signal line 19' corresponding to each row group in the corresponding electrode sheet 13' is sequentially connected to the corresponding temperature sampling point.

[0399] Step 220': Control the control switch 54' corresponding to each column group to sample the temperature detection signal of the corresponding electrode unit 33' based on the corresponding temperature sampling point. Step 240': Control the intensity of the alternating electrical signal applied to the electrode unit 33' according to the temperature detection signal.

[0400] Specifically, when it is determined that the electrode plate 13' does not need to be replaced, the alternating electrical signal applied to each electrode unit 33' in the electrode plate 13' is controlled or adjusted according to the temperature detection signal detected by the temperature detection unit 35' corresponding to each electrode unit 33' in the electrode plate 13'.

[0401] In some embodiments, controlling the intensity of the alternating electrical signal applied to the electrode unit 33' based on the temperature detection signal in step 240' specifically includes the following steps:

[0402] Step 241': Compare the temperature at each electrode unit 33' in the electrode sheet 13' with the preset temperature threshold based on the temperature detection signal.

[0403] Step 242': Control the strength of the alternating current signal based on the comparison results.

[0404] In some embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242' specifically includes:

[0405] Step 2421': If the temperature at at least one electrode unit 33' exceeds a preset temperature threshold, stop applying alternating electrical signals to the electrode units 33' of the electrode sheet 13'. Specifically, stop applying alternating electrical signals to the electrode units 33' of the electrode sheet 13' when the temperature obtained from the temperature detection signals of all the electrode units 33' of the electrode sheet 13' exceeds the preset temperature threshold. Continue applying alternating electrical signals to each electrode unit 33' of the electrode sheet 13' when the temperature obtained from the temperature detection signals of each electrode unit 33' of the electrode sheet 13' does not exceed the preset temperature threshold.

[0406] In some embodiments, stopping the application of alternating electrical signals to the electrode units 33' of the electrode sheet 13' in step 2421' specifically includes: stopping the application of alternating electrical signals to all electrode units 33' of the electrode sheet 13'; or stopping the application of alternating electrical signals to all electrode units 33' in the row group of electrode units 33' that exceed a preset temperature threshold in the electrode sheet 13'.

[0407] Furthermore, while ceasing the application of alternating electrical signals to all electrode units 33' in the row group containing electrode units 33' that exceed the preset temperature threshold, alternating electrical signals continue to be applied to electrode units 33' in other rows of electrode units 33' in electrode unit 13'. The intensity of the alternating electrical signals applied to the electrode units 33' in other rows of electrode unit 33' in electrode unit 13' is adjustable. For example, all electrode units 33' in electrode unit 13' whose temperature obtained from the temperature detection signal conversion does not exceed the preset temperature threshold and are located in different rows from the electrode units 33' whose temperature obtained from the temperature detection signal conversion exceeds the preset temperature threshold, continue to be applied with alternating electrical signals. The alternating electrical signals applied to different rows can be the same or different; for example, the voltage or current amplitude of the alternating electrical signal applied to rows closer to but not exceeding the preset temperature threshold is smaller, and vice versa.

[0408] In other embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242' specifically includes:

[0409] Step 2422': If the temperature at all electrode units 33' in the electrode sheet 13' does not exceed the preset temperature threshold, and if the temperature at all electrode units 33' in the electrode sheet 13' does not exceed the first preset temperature, then increase the intensity of the alternating electrical signal applied to the electrode units 33' of the electrode sheet 13', wherein the first preset temperature is less than the preset temperature threshold.

[0410] In step 2422', the increase in electric field intensity corresponding to each row group whose alternating electrical signal intensity is increased can be the same or different, that is, they can be adjusted separately. For example, the voltage or current amplitude of the alternating electrical signal applied to the row group with the lower highest temperature is larger, and vice versa.

[0411] Step 2423': If the temperature at all electrode units 33' in the electrode sheet 13' does not exceed the preset temperature threshold, and if the temperature at at least one electrode unit 33' in the electrode sheet 13' exceeds the first preset temperature but is less than the second preset temperature, then the alternating electrical signal strength currently applied to the electrode unit 33' of the electrode sheet 13' remains unchanged.

[0412] In step 2423', maintaining the alternating electrical signal strength currently applied to electrode unit 33' specifically includes: maintaining the alternating electrical signal strength currently applied to the first target row group, wherein the first target row group is a row group where the temperature at electrode unit 33' exceeds a first preset temperature but is less than a second preset temperature. That is, only the voltage or current amplitude of the alternating electrical signal corresponding to the row group whose temperature exceeds the first preset temperature but is less than the second preset temperature can be maintained, while the voltage or current amplitude of the alternating electrical signal corresponding to the other row groups can still be adjusted according to the temperature of the respective row group.

[0413] Step 2424': If the temperature at all electrode units 33' in the electrode sheet 13' does not exceed the preset temperature threshold, and if the temperature at at least one electrode unit 33' in the electrode sheet 13' exceeds the second preset temperature but is less than the preset temperature threshold, then reduce the intensity of the alternating electrical signal applied to the electrode unit 33' of the electrode sheet 13'.

[0414] In step 2424', reducing the intensity of the alternating electrical signal applied to the electrode unit 33' specifically includes: reducing the intensity of the alternating electrical signal applied to the electrode unit 33' of the second target row group, wherein the second target row group is a row group where the temperature at the electrode unit 33' exceeds a second preset temperature but is less than a preset temperature threshold. That is, only the voltage or current amplitude of the alternating electrical signal corresponding to the row group whose temperature exceeds the second preset temperature but is less than the preset temperature threshold can be reduced, and the reduced amplitude can be the same or different, while the voltage or current amplitude of the alternating electrical signal corresponding to the other row groups can still be adjusted according to the temperature of the corresponding row group, for example, maintained or increased.

[0415] For example, when the temperature obtained by converting the temperature detection signal is much lower than the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode sheet 13' by increasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode sheet 13'. The voltage or current amplitude of the alternating electrical signal applied to different rows may be the same or different. Alternatively, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode sheet 13' by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode sheet 13' unchanged. The voltage or current amplitude of the alternating electrical signal applied to only some rows may remain unchanged. When the temperature obtained from the temperature detection signal is close to the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode sheet 13' remains unchanged. This can be done by keeping the voltage or current amplitude of the alternating electrical signal applied to only a portion of the row groups unchanged, or by reducing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode sheet 13'. The voltage or current amplitude of the alternating electrical signal applied to different row groups can be the same or different.

[0416] In some other embodiments, controlling the alternating electrical signal strength based on the comparison result in step 242' specifically includes:

[0417] Step 2425': If the temperature at at least one electrode unit 33' exceeds a preset temperature threshold, determine the number of over-temperature rows.

[0418] Step 2426': If the number of overheated rows exceeds a preset threshold, stop applying alternating electrical signals to all electrode units 33' of electrode sheet 13'.

[0419] Step 2427': If the number of over-temperature rows does not exceed the preset number threshold, stop applying alternating electrical signals to all electrode units 33' in the row where the electrode unit 33' that exceeds the preset temperature threshold is located in the electrode sheet 13'.

[0420] Furthermore, while ceasing the application of alternating electrical signals to all electrode units 33' in the row group containing electrode units 33' that exceed the preset temperature threshold, alternating electrical signals continue to be applied to electrode units 33' in other rows of electrode units 33' in electrode unit 13'. The intensity of the alternating electrical signals applied to the electrode units 33' in other rows of electrode unit 33' in electrode unit 13' is adjustable. For example, all electrode units 33' in electrode unit 13' whose temperature obtained from the temperature detection signal conversion does not exceed the preset temperature threshold and are located in different rows from the electrode units 33' whose temperature obtained from the temperature detection signal conversion exceeds the preset temperature threshold, continue to be applied with alternating electrical signals. The alternating electrical signals applied to different rows can be the same or different; for example, the voltage or current amplitude of the alternating electrical signal applied to rows closer to but not exceeding the preset temperature threshold is smaller, and vice versa.

[0421] Step 2428': If the number of overheated rows does not exceed a preset threshold, and the temperature at each electrode unit 33' in the non-overheated rows does not exceed a first preset temperature, then increase the intensity of the alternating electrical signal applied to the electrode unit 33' of the non-overheated rows, wherein the first preset temperature is less than a preset temperature threshold.

[0422] In step 2428', the increase in electric field intensity corresponding to each row group whose alternating electrical signal intensity is increased can be the same or different, that is, they can be adjusted separately. For example, the voltage or current amplitude of the alternating electrical signal applied to the row group with the lower highest temperature is larger, and vice versa.

[0423] Step 2429': If the number of overheated rows does not exceed the preset number threshold, and if the temperature at at least one electrode unit 33' in the non-overheated rows exceeds the first preset temperature but is less than the second preset temperature, then the alternating electrical signal strength currently applied to the electrode unit 33' in the non-overheated rows remains unchanged.

[0424] In step 2429', maintaining the alternating electrical signal strength currently applied to electrode unit 33' specifically includes: maintaining the alternating electrical signal strength currently applied to the first target row group, wherein the first target row group is a row group where the temperature at electrode unit 33' exceeds a first preset temperature but is less than a second preset temperature. That is, only the voltage or current amplitude of the alternating electrical signal corresponding to the row group whose temperature exceeds the first preset temperature but is less than the second preset temperature can be maintained, while the voltage or current amplitude of the alternating electrical signal corresponding to the other row groups can still be adjusted according to the temperature of the respective row group.

[0425] Step 2430': If the number of overheated rows does not exceed a preset threshold, and if the temperature at at least one electrode unit 33' in the non-overheated rows exceeds a second preset temperature but is less than a preset temperature threshold, then reduce the intensity of the alternating electrical signal applied to the electrode unit 33' in the non-overheated rows, wherein the second preset temperature is greater than the first preset temperature but less than the preset temperature threshold.

[0426] In step 2430', reducing the intensity of the alternating electrical signal applied to the electrode unit 33' specifically includes: reducing the intensity of the alternating electrical signal applied to the electrode unit 33' of the second target row group, wherein the second target row group is a row group where the temperature at the electrode unit 33' exceeds a second preset temperature but is less than a preset temperature threshold. That is, only the voltage or current amplitude of the alternating electrical signal corresponding to the row group whose temperature exceeds the second preset temperature but is less than the preset temperature threshold can be reduced, and the reduced amplitude can be the same or different, while the voltage or current amplitude of the alternating electrical signal corresponding to the other row groups can still be adjusted according to the temperature of the corresponding row group, for example, maintained or increased.

[0427] For example, when the temperature obtained by converting the temperature detection signal is much lower than the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode sheet 13' by increasing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode sheet 13'. The voltage or current amplitude of the alternating electrical signal applied to different rows may be the same or different. Alternatively, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode sheet 13' by keeping the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode sheet 13' unchanged. The voltage or current amplitude of the alternating electrical signal applied to only some rows may remain unchanged. When the temperature obtained from the temperature detection signal is close to the preset temperature threshold, the alternating electrical signal is continued to be applied to each electrode unit 33' of the electrode sheet 13' in a manner that the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode sheet 13' remains unchanged. This can be done by keeping the voltage or current amplitude of the alternating electrical signal applied to only a portion of the row groups unchanged, or by reducing the voltage or current amplitude of the alternating electrical signal applied to each electrode unit 33' of the electrode sheet 13'. The voltage or current amplitude of the alternating electrical signal applied to different row groups can be the same or different.

[0428] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 11 The electrode type identification method shown identifies the type of electrode 13'. For details, please refer to [link / reference]. Figure 11 This will not be elaborated upon here.

[0429] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 32 The signal control method for tumor electric field therapy shown combines the control switch 54' and the bidirectional switching switch 55', which are electrically connected to the electrode sheet 13', to switch each electrode unit 33' of the electrode sheet 13' between applying an alternating electrical signal and acquiring a temperature detection signal.

[0430] Reference Figure 33 As shown, the method includes:

[0431] Step 310': Combine the control switch 54' and the bidirectional switching switch 55' that are electrically connected to the corresponding electrode sheet 13' to apply alternating electrical signals to each electrode unit 33' of the electrode sheet 13' and execute step 320';

[0432] The application of alternating electrical signals to each electrode unit 33' of electrode sheet 13' in step 310' specifically includes: simultaneously applying the same or different alternating electrical signals to the electrode units 33' of some or all row groups in all row groups.

[0433] Step 320': Combine the control switch 54' and the bidirectional switching switch 55' that are electrically connected to the electrode plate 13' to collect the temperature detection signals of each electrode unit 33' of the electrode plate 13' in a row and execute step 330;

[0434] The temperature detection signals of each electrode unit 33' of the row-collecting electrode sheet 13' in step 320' specifically include: sampling the temperature detection signals of all electrode units 33' of some or all row groups in all row groups in sequence during the same sampling time period; or sampling the temperature detection signals of some electrode units 33' of some or all row groups in all row groups in sequence during the same sampling time period.

[0435] Step 330': Determine the combined control mode of the control switch 54' and the bidirectional switching switch 55' electrically connected to the electrode 13' based on the collected temperature detection signal and execute step 340';

[0436] Step 340': Control the working state of each electrode unit 33' of the electrode sheet 13' according to the determined combination control method of control switch 54' and bidirectional switching switch 55'.

[0437] The operating states of each electrode unit 33' of the electrode sheet 13' in step 340' include at least one of the following: stopping the application of alternating current signals and continuing to acquire temperature detection signals, and stopping the acquisition of temperature detection signals and continuing to apply alternating current signals. Continuing to apply alternating current signals includes: continuing to apply alternating current signals by increasing the voltage or current amplitude of the currently applied alternating current signal, or continuing to apply alternating current signals by maintaining the voltage or current amplitude of the currently applied alternating current signal unchanged, or continuing to apply alternating current signals by decreasing the voltage or current amplitude of the currently applied alternating current signal. The methods of continuing to apply alternating current signals corresponding to different row groups can be the same or different.

[0438] The operating state of each electrode unit 33' of electrode sheet 13' is determined by the temperature detection signal it acquires. Each electrode unit 33' of electrode sheet 13' is divided into different regions. By combining control switch 54' and bidirectional switching switch 55', each electrode unit 33' in each region can be cyclically switched between applying an alternating current signal and acquiring a temperature detection signal. When applying an alternating current signal, different regions can be the same or different.

[0439] The tumor electric field therapy system 100' of this embodiment can adopt... Figure 13 The electrode temperature detection method shown detects the temperature of electrode 13'. For details, please refer to [link / reference needed]. Figure 13 This will not be elaborated upon here.

[0440] The tumor electric field therapy system 100' of this embodiment can adopt... Figures 14-16 The method of applying alternating electrical signals for tumor electric field therapy shown applies alternating electrical signals to electrode 13'. The difference is that when applying alternating electrical signals, the alternating electrical signals applied to different rows...

Claims

1. A tumor electric field therapy system, characterized in that, include: An electrode sheet includes a substrate on which multiple grounding lines and multiple dual-purpose signal lines are arranged, multiple electrode units capable of applying alternating electrical signals, and multiple temperature detection units corresponding one-to-one with the multiple electrode units. Each temperature detection unit is used to detect the temperature at the corresponding electrode unit and has a ground terminal and a signal terminal. The multiple temperature detection units are configured in the circuit as at least two row groups and at least two column groups. The ground terminals of the temperature detection units in the same column group are connected to the same grounding line, and the ground terminals of the temperature detection units in different column groups are connected in parallel through different grounding lines. The temperature detection units in the same row group are connected in series to the same dual-purpose signal line, and the signal terminals of the temperature detection units in different row groups are connected in parallel through different dual-purpose signal lines. Each dual-purpose signal line is adapted to receive an alternating electrical signal to transmit the alternating electrical signal to the electrode units in the corresponding row group or to receive a direct current signal to transmit one or more combinations of temperature detection signals from the temperature detection units in the corresponding row group. The controller is configured to: (1) determine the row group where the target electrode unit is located, wherein the target electrode unit is an electrode unit to which an alternating electrical signal needs to be applied; and (2) combine the grounding wires and dual-purpose signal lines of the control electrode sheet to transmit the alternating electrical signal to the target electrode unit.

2. The tumor electric field therapy system according to claim 1, characterized in that, When transmitting alternating electrical signals to the target electrode unit, all the grounding wires are disconnected, the dual-purpose signal line corresponding to the row group where the target electrode unit is located is connected to the alternating electrical signal, and the remaining dual-purpose signal lines are not connected to the alternating electrical signal.

3. The tumor electric field therapy system according to claim 1, characterized in that, Each of the grounding wires is grounded through a control switch connected in series with it, and each of the dual-purpose signal lines is connected to a temperature sampling point or an alternating power supply line through a bidirectional switching switch connected in series with it.

4. The tumor electric field therapy system according to claim 3, characterized in that, The bidirectional switching switch has a first terminal for receiving alternating current signals and a second terminal for receiving direct current signals. The controller controls the closing and opening of each of the control switches and the switching of each of the bidirectional switching switches to conduct either its first terminal or its second terminal.

5. The tumor electric field therapy system according to claim 4, characterized in that, When transmitting an alternating electrical signal to the target electrode unit, the controller controls all the control switches to be disconnected, the bidirectional switching switch connected in series with the dual-use signal corresponding to the row group where the target electrode unit is located is switched to conduct its first terminal, and the remaining bidirectional switching switches are all switched to conduct their respective second terminals.

6. The tumor electric field therapy system according to claim 5, characterized in that, Each of the dual-purpose signal lines is connected to the same alternating power supply line through the second terminal of its corresponding bidirectional switching switch.

7. The tumor electric field therapy system according to claim 6, characterized in that, The strength of the alternating electrical signal transmitted by the alternating power line is adjustable.

8. The tumor electric field therapy system according to claim 5, characterized in that, Each of the dual-purpose signal lines is connected to different alternating power supply lines via the second terminal of its corresponding bidirectional switching switch.

9. The tumor electric field therapy system according to claim 8, characterized in that, The intensity of the alternating electrical signal transmitted by each of the alternating power lines is adjustable.

10. The tumor electric field therapy system according to claim 1, characterized in that, When transmitting an AC signal to the target electrode unit, the controller controls all the grounding wires to be disconnected, each of the dual-purpose signal lines corresponding to the row group where the target electrode unit is located to be connected to an AC signal, and the remaining dual-purpose signal lines to be connected to a DC signal.

11. The tumor electric field therapy system according to claim 1, characterized in that, The controller is configured to determine the row group of the target electrode unit based on the region where the target electrode unit is located.

12. The tumor electric field therapy system according to any one of claims 1-11, characterized in that, It also includes an AC signal generator that provides alternating electrical signals and a power supply switch electrically connected to the AC signal generator. The controller controls whether to output the alternating electrical signals provided by the AC signal generator through the power supply switch.

13. The tumor electric field therapy system according to claim 12, characterized in that, The controller is also configured to combine control of each of the grounding wires and each of the dual-purpose signal lines to acquire one or more combinations of temperature detection signals from each of the temperature detection units in the corresponding row group, row by row.

14. The tumor electric field therapy system according to claim 13, characterized in that, The controller controls the strength of the alternating electrical signal provided by the AC signal generator based on each of the temperature detection signals.

15. The tumor electric field therapy system according to claim 13, characterized in that, The controller is configured to have a preset temperature threshold and is set to: When all the temperature detection signals are less than the preset temperature threshold, the AC signal generator is controlled to provide the electrode unit with an alternating electrical signal whose voltage or current amplitude increases, remains unchanged, or decreases. When a temperature detection signal is greater than the preset temperature threshold, the AC signal generator is controlled to stop providing the alternating electrical signal to the electrode unit.

16. The tumor electric field therapy system according to claim 15, characterized in that, The controller controls the AC signal generator to stop providing the alternating electrical signal to the electrode unit in the following specific manner: Control the power supply switch to disconnect the AC signal transmission path between the AC signal generator and each of the electrode units; or Control each of the aforementioned grounding wires to disconnect, and simultaneously control each of the aforementioned dual-purpose signal lines to switch from the end connected to the alternating current signal to the end connected to the respective direct current signal; or The control disconnects each of the grounding wires and simultaneously controls each of the dual-purpose signal lines to switch from transmitting AC signals to each of the electrode units to transmitting DC signals to the signal terminals of the temperature detection units corresponding to each of the electrode units; or The grounding wires are disconnected, and at the same time, the dual-purpose signal lines are switched from being connected to the electrode units electrically connected to them to being connected to the signal terminals of the temperature detection units electrically connected to them.

17. The tumor electric field therapy system according to claim 15, characterized in that, Stopping the AC signal generator from transmitting alternating electrical signals to the electrode units includes stopping the transmission of alternating electrical signals to all the electrode units and stopping the transmission of alternating electrical signals to each electrode unit in the row group where the temperature detection signal exceeds the preset temperature threshold, while continuing to transmit alternating electrical signals to each electrode unit in the remaining row groups.

18. The tumor electric field therapy system according to claim 13, characterized in that, When each of the temperature detection signals is much smaller than the preset temperature threshold, the controller controls the AC signal generator to provide the alternating electrical signal with increased voltage or current amplitude.

19. The tumor electric field therapy system according to claim 13, characterized in that, When a temperature detection signal approaches the preset temperature threshold, the controller controls the AC signal generator to provide an alternating electrical signal with a voltage or current amplitude that remains constant or decreases.

20. The tumor electric field therapy system according to claim 13, characterized in that, When a temperature detection signal exceeds the preset temperature threshold, the controller controls the AC signal generator to stop providing alternating electrical signals to each electrode unit in the row group where the temperature detection signal exceeds the preset temperature threshold, and continues to provide alternating electrical signals to each electrode unit in the remaining row groups.

21. A tumor treatment device, characterized in that, include: The tumor electric field therapy system according to any one of claims 1-20.

22. A method for detecting the temperature of an electrode sheet, characterized in that, The method, applied to a tumor electric field therapy system as described in any one of claims 1-20 or to a tumor treatment device as described in claim 13, comprises: Switch each of the dual-purpose signal lines to transmit DC signals; Each grounding wire is sequentially and in a time-division manner to collect temperature detection signals from one or more combined detection units in each row group, row by row. The temperature detection signal of each electrode unit is determined based on the collected temperature detection signals.

23. The method according to claim 22, characterized in that, The temperature detection signal of each electrode unit is used to determine at least one of the following: ① whether the electrode sheet is qualified; ② whether the temperature detection unit of the electrode sheet is faulty or abnormal; ③ whether the electrode sheet needs to be replaced; ④ whether the electrode sheet is overheated; ⑤ the electrode sheet type is identified; ⑥ adjust or control the intensity of the alternating electrical signal transmitted by the dual-purpose signal line.

24. The method according to claim 22, characterized in that, Whether the electrode sheet is overheated and the type of the electrode sheet are both determined under the condition that the electrode sheet is qualified.

25. The method according to claim 22, characterized in that, Whether the electrode needs to be replaced is determined based on the number of malfunctions or abnormalities in the temperature detection unit of the electrode.

26. The method according to claim 25, characterized in that, The electrode is deemed to need to be replaced when the number of its faulty or abnormal temperature detection units reaches 20% of the total number of its temperature detection units.

27. A method for judging the quality of electrode sheets, characterized in that, Applied to the tumor electric field therapy system as described in any one of claims 1-20 or the tumor treatment device as described in claim 21, the method comprises: By executing the electrode sheet temperature detection method according to claim 22, the temperature detection signal of each electrode unit in the electrode sheet is determined; The quality of the electrode sheet is determined based on the temperature detection signal.

28. The method according to claim 27, characterized in that, Determining whether the electrode sheet is qualified based on the temperature detection signal includes: Compare the temperature detection signals of each electrode unit with the preset temperature threshold; Determine whether the electrode unit is abnormal or faulty based on the comparison results; The quality of the electrode sheet is determined by whether there are any abnormalities or malfunctions in the electrode unit.

29. The method according to claim 28, characterized in that, The comparison results determine whether the electrode unit is abnormal or faulty, including: When none of the temperature detection signals exceed the preset temperature threshold, it is determined that no abnormality or malfunction has occurred in any of the electrode units. When a temperature detection signal exceeds the preset temperature threshold, it is determined that the electrode unit is abnormal or faulty.

30. The method according to claim 28 or 29, characterized in that, Determining the qualification of the electrode sheet based on whether there are abnormalities or malfunctions in the electrode unit includes: When at least one of the electrode units is abnormal or faulty, the electrode sheet is deemed unqualified. When all the electrode units are functioning normally, the electrode sheet is deemed qualified.

31. A method for identifying electrode type, characterized in that, Applied to the tumor electric field therapy system as described in any one of claims 1-20 or the tumor treatment device as described in claim 21, the method comprises: By executing the electrode sheet temperature detection method according to claim 22, the temperature detection signal of each electrode unit in the electrode sheet is determined; The type of the electrode is identified based on the temperature detection signals.

32. A computer-readable storage medium, characterized in that, It stores a computer program, which, when executed by a processor, implements... The electrode temperature detection method according to any one of claims 22-26; or The method for judging the quality of electrode sheets according to any one of claims 27-30; or The electrode type identification method according to claim 31.

33. An adapter for tumor electric field therapy, comprising a first memory and the controller, characterized in that, The first memory stores a computer program, which, when executed by the controller, implements... The electrode temperature detection method according to any one of claims 22-26; or The method for judging the quality of electrode sheets according to any one of claims 27-30; or The electrode type identification method according to claim 31.

34. An electric field generator for tumor electric field therapy, comprising a second memory and the controller, characterized in that, The second memory stores a computer program that, when executed by the controller, implements... The electrode temperature detection method according to any one of claims 22-26; or The method for judging the quality of electrode sheets according to any one of claims 27-30; or The electrode type identification method according to claim 31.

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