Artery return pipe and mechanical circulation support system

Abstract

The invention relates to an arterial return pipe and a mechanical circulation support system. A backflow channel for blood to pass through is arranged in the artery backflow pipe; the artery backflow pipe comprises a supporting section and a bending section located at the far end of the supporting section, when the artery backflow pipe is in a free state, at least part of the bending section is in a preset bending state relative to the supporting section, and the bending section can elastically deform to change the bending state; the bent section is provided with a perfusion port, the perfusion port is connected with the backflow channel, and at least part of the perfusion port faces the near end side of the artery backflow pipe, so that blood discharged from the perfusion port flows towards the near end side of the artery backflow pipe. According to the invention, backflow blood conveyed by the artery backflow tube can be prevented from flowing back in the artery.

Description

Technical Field

[0001] This invention relates to arterial return tubes and mechanical circulatory support systems. Background Technology

[0002] The incidence of cardiovascular diseases is rising year by year, and some patients may develop end-stage heart failure, for which drug treatment has limited effectiveness. Mechanical Circulatory Support (MCS) systems are used to replace or assist the heart's pumping function, including ventricular assist devices (VADs) and extracorporeal life support (ECLS). VADs partially or completely replace the heart's pumping function and do not provide gas exchange, while ECLSs include an oxygenator and provide circulatory and respiratory support through an extracorporeal circuit.

[0003] Percutaneous ventricular assist devices (pVADs) are a type of ventricular assist device (VAD), and percutaneous transseptal ventricular assist devices (PTVAs) are a type of pVAD. As an FDA-approved short-term circulatory support measure via the left atrial-femoral artery pathway, PTVA avoids the risks of open-heart surgery compared to traditional left ventricular assist devices, and is relatively inexpensive and simple to operate. A PTVA typically consists of a cardiopulmonary bypass pump, an arterial return catheter, and a left ventricular drainage catheter. During the procedure, the left ventricular drainage catheter reaches the left atrium via the femoral vein and interatrial septum, while the arterial return catheter reaches the descending aorta via the femoral artery, connecting to the cardiopulmonary bypass pump to form a complete blood circulation pathway.

[0004] Venous-arterial extracorporeal membrane oxygenation (VA-ECMO) is a type of extracorporeal life support (ECLS) that provides cardiopulmonary support for patients with cardiogenic shock. VA-ECMO typically includes a venous drainage tube, an arterial return tube, a centrifugal pump, and a membrane oxygenator. VA-ECMO can be divided into peripheral cannulation and central cannulation. Peripheral cannulation involves insertion through peripheral blood vessels (such as the femoral vein and femoral artery), while central cannulation involves insertion through the right atrium and ascending aorta. Peripherally cannulated VA-ECMO is currently the most commonly used VA-ECMO placement method in clinical practice. The arterial return tube is usually placed distally in the trunk, limbs, or cervicothoracic junction, such as the femoral artery, common carotid artery, or axillary artery, and is inserted from the distal end to the proximal end.

[0005] When an arterial return catheter is inserted distal to the aorta, the perfusion blood flow direction is opposite to the physiological blood flow direction of the aorta. This backflow of blood in the aorta increases the afterload of the left ventricle, leading to left ventricular dilation, decreased coronary perfusion and stroke volume, and potentially further complications such as cardiac thrombosis, arrhythmias, and pulmonary edema. Furthermore, the perfusion blood flow within the aorta is prone to turbulence, resulting in complications such as thrombosis, decreased blood flow velocity, insufficient distal perfusion pressure, and red blood cell destruction. Summary of the Invention

[0006] One object of the present invention is to provide an arterial reflux tube that helps to prevent backflow of refluxed blood in the artery.

[0007] Arterial return tube, wherein the arterial return tube is provided with a return channel for blood to pass through;

[0008] The arterial return tube includes a supporting section and a curved section located at the distal end of the supporting section. When the arterial return tube is in a free state, at least a portion of the curved section is in a predetermined bent state relative to the supporting section. The curved section can elastically deform to change the bent state.

[0009] The curved section is provided with an infusion port, which is connected to the return channel. At least a portion of the infusion port faces the proximal side of the arterial return tube, so that the blood discharged from the infusion port flows towards the proximal side of the arterial return tube.

[0010] In some embodiments, the curved segment includes a folded portion and a deflection portion connected to the proximal end of the folded portion, the folded portion bending towards the proximal side of the arterial reflux tube relative to the deflection portion, the deflection portion deflecting towards the radial side of the arterial reflux tube, the folded portion causing the curved segment to form a curled shape.

[0011] In some embodiments, the injection port includes a lateral injection hole disposed on the inner curved side of the deflection portion and / or the reverse fold portion.

[0012] In some embodiments, multiple lateral injection holes are provided, and the lateral injection holes are distributed along the extension direction of the curved section.

[0013] In some embodiments, when the arterial return tube is in a free state, the support section is straight, and along a direction perpendicular to the axis of the support section, the arterial return tube has a first side and a second side opposite to each other, and the curved section bends toward the first side; the infusion port includes a first opening disposed in the folded portion and a second opening disposed in the deflected portion; the first opening is oriented toward the second side, and the second opening is oriented toward the first side, so as to allow the first blood flow flowing out of the first opening and the second blood flow flowing out of the second opening to intersect.

[0014] In some embodiments, the infusion port includes a distal infusion orifice located at the distal end face of the curved segment, and the second opening includes the distal infusion orifice.

[0015] In some embodiments, the end face of the folded portion is an inclined surface that is tilted relative to the axis of the folded portion, the inclined surface is tilted toward the second side, and the inclined surface causes the end of the folded portion to form a pointed portion; the inclined surface is provided with an inclined opening, the inclined opening is tilted toward the second side, and the first opening includes the inclined opening.

[0016] In some embodiments, the farthest end of the folded portion is tilted toward the deflected portion.

[0017] In some embodiments, a transition section is also included, which connects the support section and the bending section; when the arterial return tube is in a free state, the transition section bends toward the second side relative to the support section, and the bending section bends toward the first side relative to the support section.

[0018] In some embodiments, the curved segment forms a curved plane, the support segment is located on the curved plane, and the lateral injection holes are arranged symmetrically with respect to a plane parallel to the curved plane and passing through the central axis of the curved segment.

[0019] In some embodiments, the curved section forms a curved plane, and the axis of the lateral injection hole is located on the curved plane.

[0020] Another object of the present invention is to provide a mechanical circulation support system, comprising:

[0021] Extracorporeal circulation pump, drainage catheter, and arterial return tube;

[0022] The drainage catheter is used to connect to the suction port of the extracorporeal circulation pump, and the arterial return tube is used to connect to the pump outlet of the extracorporeal circulation pump. The arterial return tube is any of the arterial return tubes described above.

[0023] The beneficial effects of this invention are:

[0024] According to an embodiment of the present invention, the arterial return tube includes a supporting section and a curved section located distal to the supporting section. When the return tube is in a free state, at least a portion of the curved section is in a predetermined bent state relative to the supporting section. By providing an infusion port in the curved section and making at least a portion of the infusion port face the proximal side of the arterial return tube, when blood in the return channel flows out from the infusion port, the blood can flow towards the proximal side of the arterial return tube, which helps to prevent the blood flow direction formed by the arterial return tube from reversing the physiological blood flow direction of the artery and forming backflow. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the structure of one embodiment of the mechanical circulation support system in this invention;

[0026] Figure 2 yes Figure 1 Schematic diagram of the middle cerebral artery reflux canal;

[0027] Figure 3 yes Figure 2 A schematic diagram of the local structure of the distal end of the middle cerebral artery reflux canal;

[0028] Figure 4 This is a schematic diagram of the blood flow path during the use of an arterial return tube;

[0029] Figure 5 This is a schematic diagram of a partial structure of the distal end of the arterial return tube in another embodiment;

[0030] Figure 6 This is a schematic diagram of the perfusion blood flow vectors at each perfusion port in one embodiment of the arterial return tube;

[0031] Figure 7 yes Figure 6 A schematic diagram of the synthesis of various perfusion blood flow vectors;

[0032] Figure 8 These are schematic diagrams showing the placement of the lateral injection holes on the cross-section of the curved section in two different embodiments;

[0033] Figure 9 This is a schematic diagram of the structure at the end of the curved section in another embodiment.

[0034] List of feature names corresponding to the labels in the figure:

[0035] 100. Extracorporeal circulation pump;

[0036] 200. Arterial reflux tube; 201. First side; 202. Second side; 203. Reflux channel;

[0037] 210. Support section; 220. Bending section; 221. Deflection section; 222. Reverse bending section; 2221. Inclined surface; 2222. Tip; 2223. Opening of the inclined surface; 2224. Bending plane;

[0038] 230. Injection port; 231. First opening; 232. Second opening;

[0039] 241. Lateral injection hole;

[0040] 242. Distal injection hole;

[0041] 250. Transition section;

[0042] 260. Clamping tubing; 261. Tailstock; 262. Hemostatic valve; 2611. Standard Luer collateral branch;

[0043] 300. Drainage catheter;

[0044] 410. Heart; 411. Left atrium; 412. Right atrium; 413. Left superior pulmonary vein; 420. Descending aorta; 430. Femoral vein; 440. Femoral artery;

[0045] 510. Direction of physiological blood flow in the aorta; 520. First blood flow; 530. Second blood flow. Detailed Implementation

[0046] The present invention will now be described in further detail with reference to the accompanying drawings and specific embodiments. Similar elements in different embodiments are referred to by related similar element reference numerals. In the following embodiments, many details are described to facilitate a better understanding of the present application. However, those skilled in the art will readily recognize that some features may be omitted in different situations, or may be replaced by other elements, materials, or methods. In some cases, certain operations related to the present application are not shown or described in the specification. This is to avoid obscuring the core parts of the present application with excessive description. For those skilled in the art, detailed description of these related operations is not necessary; they can fully understand the related operations based on the description in the specification and general technical knowledge in the art.

[0047] The embodiments described in the detailed implementation can be combined in any suitable manner without contradiction. For example, different implementation methods can be formed by combining different embodiments. In order to avoid unnecessary repetition, the various possible combinations of the embodiments will not be described separately.

[0048] Furthermore, the features, operations, or characteristics described in the specification can be combined in any suitable manner to form various embodiments. At the same time, the steps or actions in the method description can be rearranged or adjusted in a manner obvious to those skilled in the art. Therefore, the various orders in the specification and drawings are only for the clear description of a particular embodiment and do not imply a necessary order, unless otherwise stated that a particular order must be followed.

[0049] The serial numbers assigned to components in this document, such as "first" and "second," are used only to distinguish the described objects and have no sequential or technical meaning. The terms "connection" and "linkage" used in this application, unless otherwise specified, include both direct and indirect connections (linkages).

[0050] In some embodiments, please refer to Figure 1 The mechanical circulatory support system includes an extracorporeal circulation pump 100, a drainage catheter 300, and an arterial return catheter 200. It should be noted that, as examples, the mechanical circulatory support system may be a percutaneous transatrial septal left ventricular assist device (PTVA) that draws blood from the left ventricular system, or a venous-arterial extracorporeal membrane oxygenation (VA-ECMO) device that draws blood from the femoral vein 430 or internal jugular vein, etc.

[0051] Those skilled in the art will understand that the drainage catheter 300 is used to connect to the suction port of the extracorporeal circulation pump 100, and the arterial return tube 200 is used to connect to the pump outlet of the extracorporeal circulation pump 100. Figure 1 The extracorporeal circulation pump 100 can draw blood from the left ventricular system through the drainage catheter 300 and then deliver it to the arterial system through the arterial return tube 200, thereby replacing or assisting the left ventricular pumping function.

[0052] The extracorporeal circulation pump 100 can be of any suitable type, such as a peristaltic pump or a centrifugal pump. The drainage catheter 300 can be percutaneously inserted into the left ventricular system to drain blood from the left ventricular system to the extracorporeal circulation pump 100. This can, for example, reduce left ventricular filling pressure, alleviate pulmonary congestion and pulmonary edema, and relieve left ventricular load. The arterial return catheter 200 is used to return the pressurized blood from the extracorporeal circulation pump 100 to the systemic circulation, for example, by injecting it into the aorta through the femoral artery 440, maintaining perfusion of the corresponding organs and ensuring blood and oxygen supply to vital organs. The specific structures of the extracorporeal circulation pump 100 and the arterial return catheter 200 can be referenced from existing structures in related technologies. Considering that they are not directly related to the innovative content and technical problem to be solved in this application, they will not be elaborated here. The local systemic circulation of the human body can be referenced... Figure 1 It includes the heart 410, descending aorta 420, femoral vein 430, and femoral artery 440. The heart 410 includes the left atrium 411, right atrium 412, and left superior pulmonary vein 413.

[0053] The structure of the arterial reflux tube 200 will be introduced below.

[0054] In some embodiments, please refer to Figure 2 The arterial return tube 200 includes a clamping hose 260 located proximally, a tube body connected to the distal end of the clamping hose 260, and a hemostatic valve 262 and a tailstock 261 connected to the proximal end of the clamping hose 260. The clamping hose 260 can be integrally extruded from PVC or PU material with anti-collapse capability, and can be clamped and deformed to close the lumen. The tube body includes a support section 210 and a curved section 220 located distal to the support section 210. The arterial return tube 200 has a return channel 203 (obscured in the figure, not shown), which allows blood to pass through, thereby delivering blood pumped by the extracorporeal circulation pump 100 to the arterial blood vessels through the distal part of the arterial return tube 200. The return channel 203 can be formed by sequentially connecting the inner lumens of the tailstock 261, the clamping hose 260, and the tube body. The hemostatic valve 262 can be quickly connected and disconnected from the tailstock 261. It consists of a valve seat with a Luer connector and a common silicone sealing gasket. Its main function is to provide hemostasis for the arterial return tube 200 during the insertion and removal of the dilator, preventing excessive blood loss from the patient. The tailstock 261 is equipped with a Luer locking connector that can be quickly connected to the pump outlet of the extracorporeal circulation pump 100 and the detachable hemostatic valve 261. The hemostatic valve 261 can be disconnected from the pump outlet of the extracorporeal circulation pump 100 by removing it. The tailstock 261 also comes with a standard Luer side branch 2611, which can be used for intraoperative blood aspiration and preoperative air evacuation.

[0055] Those skilled in the art should understand that the terms "proximal" and "distal" used in this article are conventional medical terms. For the instrument to be operated on, the proximal end is the end closer to the user, and the distal end is the end furthest from the user, usually the end that first enters the patient's body. For more information on proximal and distal ends, please refer to [reference needed]. Figure 2 The orientation shown in the diagram. Accordingly, the proximal-distal direction is the direction from the proximal end to the distal end or from the distal end to the proximal end of the corresponding component.

[0056] In some embodiments, the arterial return tube 200 includes a supporting section 210 and a curved section 220 located distal to the supporting section 210. When the arterial return tube 200 is in a free state, the supporting section 210 is straight, and at least a portion of the curved section 220 is bent relative to the supporting section 210. The curved section 220 is provided with an infusion port 230, which is connected to the return channel 203. At least a portion of the infusion port 230 faces the proximal side of the arterial return tube 200, so that blood discharged from the infusion port 230 flows towards the proximal side of the arterial return tube 200. Those skilled in the art will understand that the supporting section 210 can provide support for the distal portion of the arterial return tube 200 and transmit operating forces to move the distal portion of the arterial return tube 200.

[0057] By providing a curved section 220 and an infusion port 230 on the curved section 220 facing the proximal side of the arterial return tube 200, the blood discharged from the infusion port 230 flows towards the proximal side of the arterial return tube 200, that is, it flows towards the proximal side in a direction parallel to the axis of the support section 210, or it flows towards the proximal side at an angle relative to the axis of the support section 210. Since the insertion direction of the arterial return tube 200 is against the direction of physiological blood flow in the artery, if blood is injected into the artery directly through the opening at the distal end of the arterial return tube 200, it will cause backflow, thereby increasing the afterload of the heart 410 and creating local turbulence and blood flow stagnation areas in the artery, which can easily lead to thrombus formation. However, when the present invention adopts the above solution, it can prevent the blood flowing out of the infusion port 230 from forming backflow.

[0058] It should be noted that the curved section 220 can elastically deform to change its bending state, thereby enabling it to enter the arterial blood vessel. The elastic deformation of the curved section 220 can be achieved by the elasticity of the corresponding part of the tube body itself. Through the elastic deformation of the curved section 220, before inserting the arterial return tube 200 into the artery, a straight dilator can be inserted into the return channel of the arterial return tube 200. The curved section 220 can tend to be straight under the constraint of the dilator, so as to puncture the blood vessel and enter the arterial blood vessel, thereby reaching the target site. After the dilator is removed, the curved section 220 can return to the preset bending state by elastic deformation.

[0059] In some embodiments, please refer to Figure 2 and Figure 3 The curved segment 220 includes a folded portion 222 and a deflection portion 221 connected to the proximal end of the folded portion 222. The folded portion 222 bends towards the proximal side of the arterial return tube 200 relative to the deflection portion 221, while the deflection portion 221 deflects towards the radial side of the arterial return tube 200. The folded portion 222 causes the curved segment 220 to form a coiled shape. When the infusion port 230 includes a distal infusion hole 242 located on the distal end face of the curved segment 220, the orientation of the distal infusion hole 242 can be directly changed by providing the folded portion 222, thereby changing the flow direction of blood flowing out of the arterial return tube 200 in the artery. This also avoids continuous impact when the infusion port 230 is close to the blood vessel wall, which helps to reduce damage to the vascular intima.

[0060] In some embodiments, the infusion port 230 includes a lateral infusion hole 241 disposed on the inner curved side of the deflection portion 221 and / or the folded portion 222, so that the infusion port 230 faces the proximal side of the arterial return tube 200, and the blood discharged from the infusion port 230 can flow towards the proximal side of the arterial return tube 200. The inner curved side is also the side near the center of the bend in the curved section 220, for example... Figure 3 The lower half of the deflection portion 221 and the folded portion 222. It should be noted that in some embodiments, the bent segment 220 may also be in other preset bending states, such as a minor arc or a semi-circle.

[0061] The number of lateral injection holes 241 is not limited. In some embodiments, multiple lateral injection holes 241 are provided, and the lateral injection holes 241 are distributed along the extension direction of the curved section 220. In some other embodiments, there may be only one, two, or more than four lateral injection holes 241. The number of lateral injection holes 241 located at the same cross-section of the curved section 220 may also be two or more. For example, in some embodiments, the curved section 220 forms a curved plane 2224, which is parallel to the adjacent... Figure 3 The plane of the paper in which it is located, and the support segment 210 is located on the curved plane 2224. For example... Figure 8 In Figure (a), the lateral perfusion holes 241 are arranged symmetrically with respect to the bending plane 2224 and passing through the central axis of the bending segment 220. This arrangement helps maintain the integrity of the inner bending side (the side closer to the center of the bend) of the bending segment 220, thereby preventing the collapse of the lateral perfusion holes 241 and deformation of the bending segment 220 when the bend is large. It also helps ensure the stability and flow rate of blood flow. In some embodiments, the axes of the two symmetrical lateral perfusion holes 241 can be symmetrically arranged at an angle of 25° to 45° with respect to the bending plane 2224 (e.g., ...). Figure 8(θ in the text). In some embodiments, two symmetrical lateral injection holes 241 form a group, and each group of lateral injection holes 241 is distributed along the extension direction of the curved section 220. For example... Figure 3 and Figure 4 There are six lateral injection holes 241, which are divided into three groups, and there is one distal injection hole 242.

[0062] In some other embodiments, such as Figure 8 In Figure (b), the curved section 220 forms a curved plane 2224, and the axis of the lateral perfusion port 241 is located on the curved plane 2224, which is conducive to making the perfusion blood flow more directly along the physiological blood flow direction 510 of the aorta and reducing the impact on the blood vessel wall.

[0063] In some embodiments, along a direction perpendicular to the axis of the support section 210, the arterial return tube 200 has opposing first sides 201 and second sides 202, with the curved section 220 curved toward the first side 201; the infusion port 230 includes a first opening 231 disposed in the folded portion 222 and a second opening 232 disposed in the deflection portion 221; the orientation of the first opening 231 is biased toward the second side 202, and the orientation of the second opening 232 is biased toward the first side 201, so that the first blood flow 520 flowing out of the first opening 231 and the second blood flow 530 flowing out of the second opening 232 intersect. In this way, the components of the first blood flow 520 and the second blood flow 530 in the direction perpendicular to the proximal and distal ends can be at least partially canceled out, which is beneficial to ensuring that the overall direction of the perfusion blood flow formed by the arterial return tube 200 is consistent with the physiological blood flow direction 510 of the aorta.

[0064] In some specific embodiments, please refer to Figure 6 and Figure 7 Each lateral perfusion orifice 241 has a different opening angle α and orifice diameter to form perfusion blood flow vectors with different directions and velocities (including...). Figure 5 and Figure 6 The vectors b, c, and d in the vectors are combined and superimposed to form vector a at the intersection point and distal perfusion orifice 242 of each perfusion blood flow vector, as shown in the figure. Figure 7 As shown, the vertically downward perfusion blood flow principal vector is finally obtained. Figure 6 The illustration shows an example of the superposition of various perfusion blood flow vectors. Figure 6 (a) shows the perfusion flow vectors before synthesis. Figure 6 (b) shows the vector e synthesized from vectors a and c. Figure 6 (c) shows the vector f synthesized from vectors d and e. Figure 6 (d) shows the synthesis of vectors b and f, both of which are aligned with the physiological blood flow direction 510 of the aorta.

[0065] In some specific embodiments, please refer to Figure 3 and Figure 4 The perfusion port 230 includes a distal perfusion orifice 242, which is located on the distal end face of the curved section 220. The second opening 232 also includes the distal perfusion orifice 242. By cooperating with the lateral perfusion orifice 241, the overall direction of the perfusion blood flow is adjusted, which helps to better avoid backflow. In some embodiments, the perfusion blood in the arterial return tube 200 is divided into lateral blood flow and main blood flow after passing through multiple lateral perfusion orifices 241 along the axis of the curved section 220. The lateral blood flow flows out from the lateral perfusion orifice 241, while the main blood flow flows out from the distal perfusion orifice 242 after being decelerated through multiple stages by the lateral perfusion orifice 241.

[0066] In some other embodiments, both the first opening 231 and the second opening 232 may be formed by a lateral injection port 241. Additionally, the injection port 230 may also include a forward injection port, which may be, for example, located at the connection between the folded portion 222 and the deflected portion 221 (e.g., Figure 3 The lateral injection hole 241 (marked with a dotted line in the image) is oriented parallel to the proximal and distal directions of the support section 210.

[0067] In some embodiments, the distal end of the folded portion 222 is tilted toward the deflected portion 221, which facilitates the orientation of the second opening 232 toward the first side 201 and also helps to avoid damage to blood vessels by the edge formed at the distal end of the curved segment 220.

[0068] In some other embodiments, please refer to Figure 9 The distal end face of the folded portion 222 is an inclined surface 2221, which is tilted relative to the axis of the folded portion. The inclined surface 2221 faces the second side at an angle, forming a pointed end 2222 at the end of the folded portion 222. An inclined opening 2223 is provided on the inclined surface 2221, which faces the second side. The first opening 231 includes the inclined opening 2223, which is also the distal irrigation port 242. By providing the inclined surface 2221, a soft, angled tip can be obtained at the end of the curved section 220, which helps reduce damage to the vessel wall during cannulation, and the inclined opening 2223 helps reduce flow resistance. It should be noted that the inclined surface 2221 can be curved or straight.

[0069] In some embodiments, the arterial return conduit 200 further includes a transition section 250, which connects the supporting section 210 and the bending section 220. When the arterial return conduit 200 is in a free state, the transition section 250 bends towards the second side 202 relative to the supporting section 210, and the bending section 220 bends towards the first side 201 relative to the supporting section 210. Those skilled in the art will understand that when the arterial return conduit 200 has the bending section 220, the bending section 220 will occupy a larger radial space of the return conduit, while the bending of the transition section 250 towards the first side 201 helps to avoid contact and friction between the supporting section 210 and the inner wall of the artery. The transition section 250 is not a necessary structure; in some other embodiments, the supporting section 210 and the bending section 220 can be directly connected, for example... Figure 5 As shown.

[0070] like Figure 1 In some embodiments, when the mechanical circulatory support system is operating, the extracorporeal circulation pump 100 draws blood from the left atrium 411 via the drainage conduit 300 and then pumps the blood back to the descending aorta 420 via the arterial return conduit 200. The bend 220 and the infusion port 230 of the arterial return conduit 200 allow the blood discharged from the infusion port 230 to flow towards the proximal side of the arterial return conduit 200, thereby helping to avoid backflow and thus avoiding increased afterload on the heart 410. It also avoids local turbulence and blood flow stagnation areas caused by backflow, which helps to reduce thrombus formation. The fold 222 also prevents the distal infusion port 242 from continuously impacting the vessel wall when it is close to the vessel wall, which helps to reduce damage to the vascular intima.

[0071] An embodiment of the arterial reflux tube in this invention:

[0072] The specific structure of the arterial return tube 200 can be the same as that of the arterial return tube 200 in any embodiment of the above-described mechanical circulation support system, and will not be described in detail here.

[0073] The above examples illustrate the present invention only to aid in understanding it and are not intended to limit the scope of the invention. Those skilled in the art can make various simple deductions, modifications, or substitutions based on the principles of this invention.

Claims

1. An arterial reflux tube, characterized in that, The arterial return tube is equipped with a return channel for blood to pass through; The arterial return tube includes a supporting section and a curved section located at the distal end of the supporting section. When the arterial return tube is in a free state, at least a portion of the curved section is in a predetermined bent state relative to the supporting section. The curved section can elastically deform to change the bent state. The curved section is provided with an infusion port, which is connected to the return channel. At least a portion of the infusion port faces the proximal side of the arterial return tube, so that the blood discharged from the infusion port flows towards the proximal side of the arterial return tube.

2. The arterial reflux tube as described in claim 1, characterized in that, The curved segment includes a folded portion and a deflection portion connected to the proximal end of the folded portion. The folded portion bends toward the proximal side of the arterial reflux tube relative to the deflection portion, and the deflection portion deflects toward the radial side of the arterial reflux tube. The folded portion causes the curved segment to form a curled shape.

3. The arterial reflux tube as described in claim 2, characterized in that, The injection port includes a lateral injection hole, which is located on the inner curved side of the deflected portion and / or the reversed portion.

4. The arterial reflux tube as described in any one of claims 2 to 3, characterized in that, When the arterial return tube is in a free state, the supporting section is straight. Along a direction perpendicular to the axis of the supporting section, the arterial return tube has a first side and a second side opposite to each other, and the curved section bends toward the first side. The infusion port includes a first opening disposed in the folded portion and a second opening disposed in the deflected portion. The first opening is oriented toward the second side, and the second opening is oriented toward the first side, so that the first blood flow flowing out of the first opening and the second blood flow flowing out of the second opening intersect.

5. The arterial reflux tube as described in claim 4, characterized in that, The end face of the folded portion is an inclined plane that is tilted relative to the axis of the folded portion. The inclined plane is tilted toward the second side, and the inclined plane causes the end of the folded portion to form a pointed part. The inclined plane is provided with an inclined opening, and the inclined opening is tilted toward the second side. The first opening includes the inclined opening.

6. The arterial reflux tube as described in claim 4, characterized in that, The farthest end of the folded portion is inclined toward the deflected portion.

7. The arterial reflux tube as described in claim 4, characterized in that, It also includes a transition section, which connects the support section and the bending section; when the arterial return tube is in a free state, the transition section bends toward the second side relative to the support section, and the bending section bends toward the first side relative to the support section.

8. The arterial reflux tube as described in claim 3, characterized in that, The curved section forms a curved plane, the support section is located on the curved plane, and the lateral injection holes are arranged symmetrically with respect to the curved plane and passing through the central axis of the curved section.

9. The arterial reflux tube as described in claim 3, characterized in that, The curved section forms a curved plane, and the axis of the lateral injection hole is located on the curved plane.

10. A mechanical circulation support system, characterized in that, include: Extracorporeal circulation pump, drainage catheter, and arterial return tube; The drainage catheter is used to connect to the suction port of the extracorporeal circulation pump, and the arterial return tube is used to connect to the pump outlet of the extracorporeal circulation pump. The arterial return tube is the arterial return tube according to any one of claims 1 to 9.

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