Special constant-temperature thawing and dissolving device for medical fibrinogen

Abstract

The invention discloses a special constant-temperature thawing and dissolving device for medical fibrinogen, and relates to the technical field of medical auxiliary instruments, the special constant-temperature thawing and dissolving device for medical fibrinogen comprises a heat preservation box body, and a circulating hot water supply device, a constant-temperature preheating tank, an infusion doser and a dissolving tank which are integrated in the heat preservation box body, the circulating hot water supply device is arranged on one side of an inner cavity of the heat preservation box body; a porous placing frame is placed in the constant-temperature preheating tank, a disposable pipetting mechanism is arranged on the infusion doser, a magnetic shaking table is installed in the center of an inner cavity of the dissolving tank, the preheating function and the dissolving function are integrated into one device, hot water is conveyed to the constant-temperature preheating tank through the circulating hot water supply device for preliminary preheating, and then medicine bottles are transferred to the dissolving tank for dissolving; the process is orderly linked, the tedious step-by-step operation is avoided, the pollution risk is reduced, the operation is simplified, medical fibrinogen thawing and dissolving can be more efficiently and stably completed, and the working efficiency and quality are improved.

Description

Technical Field

[0001] This invention relates to the field of medical auxiliary device technology, specifically to a constant temperature thawing and dissolving device for medical fibrinogen. Background Technology

[0002] As a biological agent, human fibrinogen requires a rigorous and complex reconstitution process before clinical use. As indicated in the instructions, the powder and dissolving solution must be preheated to 30-37°C, gently mixed and dissolved in a specific manner, and then infused using an infusion set with a filter at a rate of approximately 60 drops / minute. Currently, medical institutions generally rely on manual operation by healthcare professionals: using a water bath for preheating and maintaining the temperature, and manually shaking the vial to dissolve the drug. While specialized incubators and magnetic stirrers exist, these are not specifically designed for the characteristics of this drug, and manual coordination of each step is still necessary.

[0003] Existing general-purpose equipment involves preheating, dissolving, and injecting in separate steps, which is cumbersome and increases the risk of contamination. Secondly, general-purpose constant temperature equipment has large temperature fluctuations, and general-purpose stirrers are prone to damaging protein structures due to shear force. The dissolution endpoint is determined entirely by human experience, which is difficult to standardize. The differences in operation among different medical staff directly affect the efficacy and safety of the drug. Therefore, we propose a medical fibrinogen-specific constant temperature thawing and dissolution device. Summary of the Invention

[0004] The purpose of this invention is to address the problems of existing general-purpose equipment combinations, which involve separate steps for preheating, dissolving, and liquid injection, resulting in cumbersome operation and increased risk of contamination; secondly, general-purpose constant temperature equipment suffers from large temperature fluctuations, and general-purpose stirrers are prone to damaging protein structures due to shear force; the dissolution endpoint is determined entirely by human experience, making standardization difficult; and the differences in operation among different medical personnel directly affect the efficacy and safety of the drug. This invention provides a medical fibrinogen-specific constant temperature thawing and dissolution device.

[0005] To achieve the above objectives, the present invention specifically adopts the following technical solution:

[0006] A medical fibrinogen-specific constant-temperature thawing and dissolution device includes an insulated box, and a circulating hot water supply, a constant-temperature preheating tank, an infusion dispenser, and a dissolution tank integrated within the insulated box. The circulating hot water supply is located on one side of the inner cavity of the insulated box. A perforated rack is placed inside the constant-temperature preheating tank, and the infusion dispenser is equipped with a disposable pipetting mechanism. A magnetic shaker is installed at the center of the inner cavity of the dissolution tank, and a dissolution monitor is installed in the magnetic shaker corresponding to the middle of the medicine bottle. Sterile water is filled at the bottom of the inner cavities of the constant-temperature preheating tank and the dissolution tank, and the sterile water submerges the perforated rack and the magnetic shaker. The inlet end of the circulating hot water supply is connected to the upper side of the inner cavity of the constant-temperature preheating tank and the dissolution tank, respectively, and the outlet end of the circulating hot water supply is connected to the center of the bottom of the constant-temperature preheating tank and the dissolution tank, respectively.

[0007] Furthermore, a miniature circulating water pump is installed at the top of the inner cavity of the circulating hot water supply unit, and the output end of the miniature circulating water pump pumps sterile water evenly downward through a long strip-shaped dispensing seat with multiple drip holes evenly opened at the bottom. A PTC heater is embedded in the middle of the inner cavity of the circulating hot water supply unit, and water temperature sensors are fixedly installed on the side walls of the constant temperature preheating tank and the dissolving tank corresponding to the middle of the medicine bottle. The miniature circulating water pump, the PTC heater and the water temperature sensor are all electrically connected to the PLC control terminal.

[0008] Furthermore, the upper side of the inner cavity of the constant temperature preheating tank and the dissolving tank is fixedly connected to an inlet nozzle, and the inlet end of the micro circulating water pump is connected to the inlet nozzle through a pipe buried in the side wall of the insulated box. The bottom center of the constant temperature preheating tank is fixedly connected to a preheating distribution plate, and the bottom center of the dissolving tank is fixedly connected to a dissolving distribution plate. Both the preheating distribution plate and the dissolving distribution plate are hollow cylinders with multiple connecting holes evenly spaced on the side wall. The bottom center of the preheating distribution plate and the dissolving distribution plate is connected to the bottom center of the circulating hot water supply through a medical hose. The upper end of the dissolving distribution plate is fixedly connected to the bottom of the magnetic shaker.

[0009] Furthermore, the magnetic shaker includes a magnetic cylinder base, with multiple electromagnets embedded at equal intervals at the upper end of the magnetic cylinder base. The upper ends of the multiple electromagnets are respectively fixedly connected to ferromagnetic adsorption blocks via compression connecting springs. The upper ends of the multiple ferromagnetic adsorption blocks are fixedly connected to a medicine bottle shaker, and the medicine bottle shaker is placed concentrically with the magnetic cylinder base. A medicine bottle insertion hole is opened at the center of the medicine bottle shaker, and a rubber friction sleeve is fixedly connected to the inner wall of the insertion hole.

[0010] Furthermore, the dissolution monitor is installed at the bottom of the medicine bottle holder near the central medicine bottle insertion hole. The dissolution monitor includes an auxiliary light source and an optical sensor arranged opposite each other, and the auxiliary light source and optical sensor are positioned close to the medicine bottle inserted into the center of the medicine bottle holder.

[0011] Furthermore, the disposable pipetting mechanism includes a transfer frame, the front side of which has a docking slot, and a transfer needle with a filter is inserted into the docking slot.

[0012] Furthermore, the infusion dosing device is positioned between the constant temperature preheating tank and the dissolving tank, and a square slot is provided on the rear side of the infusion dosing device. A gas spring telescopic rod sleeve is movably inserted into the square slot on the rear side of the infusion dosing device. A piston inner rod is movably inserted into the bottom of the gas spring telescopic rod sleeve. The bottom of the piston inner rod is fixedly connected to the bottom of the square slot on the rear side of the infusion dosing device, and an ejection spring is provided between the upper end of the piston inner rod and the top of the inner cavity of the gas spring telescopic rod sleeve. The upper end of the gas spring telescopic rod sleeve is fixedly connected to the rear side of the transfer frame, and a vent valve at the top of the gas spring telescopic rod sleeve passes through the transfer frame.

[0013] Furthermore, the filter transfer needle is a double-headed needle with a hollow flat round piece fixed in the middle that matches the docking slot, and a filter screen is fixedly connected in the middle of the hollow flat round piece. The size of the docking slot matches the mouth of the medicine bottle, and a through hole is opened at the bottom center of the docking slot.

[0014] Furthermore, the infusion dosing device has multiple storage slots at equal intervals on its upper end, and a storage cylinder is movably inserted into the storage slot. The storage cylinder is a hollow cylinder with an open side wall, and a disposable transfer needle with a filter is placed inside the storage cylinder.

[0015] Furthermore, an insulated box cover is fixedly connected to the upper back side of the insulated box body, and a sealing pressure plate is fixedly connected to the inner side of the insulated box cover corresponding to the positions of the constant temperature preheating tank and the melting tank, and a PLC control terminal is embedded in the insulated box cover.

[0016] The beneficial effects of this invention are as follows:

[0017] 1. This invention integrates preheating and dissolving functions into a single device. First, a circulating hot water supply delivers hot water to the constant-temperature preheating tank for initial preheating. Then, the medicine bottle is transferred to the dissolving tank for dissolution. This sequential process avoids cumbersome step-by-step operations, reduces the risk of contamination, and simplifies operation. The inlet of the circulating hot water supply is connected to the upper side of the inner cavity of both the constant-temperature preheating tank and the dissolving tank, while the outlet is connected to the center of their bottoms, continuously providing hot water at a suitable temperature to ensure stable ambient temperature during preheating and dissolution. During dissolution, the circulating hot water supply continuously supplies hot water to the dissolving tank, maintaining a constant temperature and providing stable temperature conditions for the thawing and dissolution of medical fibrinogen, thus ensuring efficacy and safety. The dissolving tank uses a magnetic shaker, mimicking the hand-shaking of the medicine bottle to accelerate dissolution, avoiding the shear force of traditional stirrers that damages the protein structure and protecting efficacy. A dissolution monitor is installed inside the magnetic shaker of the dissolving tank, corresponding to the middle of the medicine bottle, to monitor the dissolution status in real time, accurately determine the dissolution endpoint, standardize operations, reduce the impact of differences in operation among medical personnel, and improve efficacy and safety. The entire process is simple to operate and can complete the thawing and dissolution of medical fibrinogen more efficiently and stably, improving work efficiency and quality.

[0018] 2. The miniature circulating water pump of this invention can more precisely pump sterile water through a long strip-shaped dispensing seat to the circulating hot water supply unit, where it is heated by a PTC heater to ensure a constant water temperature. Water temperature sensors installed on the side walls of the constant temperature preheating tank and dissolving tank, corresponding to the middle of the medicine bottle, can monitor the water temperature in real time and feed the data back to the PLC control terminal. Based on the received water temperature data, the PLC control terminal intelligently adjusts the pumping speed of the miniature circulating water pump and the heating power of the PTC heater, thereby maintaining a stable water temperature throughout the system. This provides a more precise and stable temperature environment for the thawing and dissolution of medical fibrinogen, further ensuring efficacy and safety of use.

[0019] 3. When the magnetic shaker of this invention is powered on, multiple electromagnets sequentially and cyclically generate magnetic force, attracting corresponding ferromagnetic adsorption blocks to move downwards, while the corresponding compression connecting springs are compressed. When the current of the electromagnets changes periodically, the ferromagnetic adsorption blocks will move up and down reciprocally under the elastic force of the compression connecting springs, thereby driving the medicine bottle shaker to shake, achieving the effect of mimicking a human hand rotating and shaking a medicine bottle, accelerating the dissolution process of medical fibrinogen. The medicine bottle insertion hole in the center of the medicine bottle shaker and the rubber friction sleeve fixedly connected to the inner wall can better fix the medicine bottle, preventing it from slipping or colliding and being damaged during shaking, ensuring the smooth progress of the dissolution process. At the same time, this magnetically driven method avoids the shear force that may be generated by traditional stirrers, which can damage the protein structure, thus maximizing the protection of the efficacy of medical fibrinogen. Attached Figure Description

[0020] Figure 1 This is a perspective view of the present invention;

[0021] Figure 2 This is a front sectional view of the present invention;

[0022] Figure 3 This is the present invention. Figure 2 Enlarged view of point A in the middle;

[0023] Figure 4 This is a side sectional view of the present invention.

[0024] In the diagram: 1. Insulated box; 2. Circulating hot water supply; 3. Constant temperature preheating tank; 4. Infusion dosing device; 5. Dissolving tank; 6. Miniature circulating water pump; 7. PTC heater; 8. Insulated hose; 9. Preheating dispensing tray; 10. Dissolving dispensing tray; 11. Inlet nozzle; 12. Multi-hole rack; 13. Magnetic cylinder base; 14. Dissolving monitor; 15. Medicine bottle shaker; 16. Electromagnet; 17. Ferromagnetic adsorption block; 18. Compression connecting spring; 19. Gas spring telescopic rod sleeve; 20. Piston inner rod; 21. Transfer rack; 22. Docking slot; 23. Transfer needle with filter; 24. Vent valve; 25. Insulated box lid; 26. Sealing plate; 27. Storage slot; 28. Storage cylinder; 29. ​​Water temperature sensor. Detailed Implementation

[0025] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings.

[0026] Please see Figures 1-4This invention provides a medical fibrinogen-specific constant temperature thawing and dissolution device, including an insulated box 1, and a circulating hot water supply 2, a constant temperature preheating tank 3, an infusion dosing device 4, and a dissolution tank 5 integrated within the insulated box 1. The circulating hot water supply 2 is located on one side of the inner cavity of the insulated box 1. A porous placement rack 12 is placed inside the constant temperature preheating tank 3, and a disposable liquid transfer mechanism is provided on the infusion dosing device 4. A magnetic shaker is installed at the center of the inner cavity of the dissolution tank 5, and a dissolution monitor 14 is provided in the magnetic shaker corresponding to the middle of the medicine bottle. Sterile water is filled at the bottom of the inner cavities of the constant temperature preheating tank 3 and the dissolution tank 5, and the sterile water submerges the porous placement rack 12 and the magnetic shaker. The inlet end of the circulating hot water supply 2 is connected to the upper side of the inner cavity of the constant temperature preheating tank 3 and the dissolution tank 5, respectively, and the outlet end of the circulating hot water supply 2 is connected to the bottom center of the constant temperature preheating tank 3 and the dissolution tank 5, respectively.

[0027] The working principle and usage process of this invention are as follows: First, the medical fibrinogen vials to be thawed and dissolved, along with the dissolving solution vials, are placed on a porous rack 12 within a constant-temperature preheating tank 3. Hot water at a suitable temperature is supplied to the constant-temperature preheating tank 3 via a circulating hot water supply 2 to preheat the vials. After preheating for a period of time, the dissolving solution is drawn out using a syringe and injected into the medical fibrinogen vials. Then, the vials containing the dissolved solution are transferred to a magnetic shaker within a dissolving tank 5. The magnetic shaker in the dissolving tank 5 begins operation, mimicking hand shaking to agitate the vials and accelerate the dissolution process. Simultaneously, a dissolution monitor 14 monitors the dissolution status of the solution in real time. During the dissolution process, the circulating hot water supply 2 continuously provides hot water to the dissolution tank 5 to maintain a constant temperature environment. Once the solution is completely dissolved, the vials can be removed for subsequent use. The entire process is simple to operate and can more efficiently and stably complete the thawing and dissolution of medical fibrinogen.

[0028] The preheating and dissolving functions are integrated into one device. First, a circulating hot water supply unit 2 supplies hot water to the constant-temperature preheating tank 3 for initial preheating. Then, the medicine bottle is transferred to the dissolving tank 5 for dissolution. This process is seamlessly connected, avoiding cumbersome step-by-step operations, reducing the risk of contamination, and simplifying operation. The inlet of the circulating hot water supply unit 2 is connected to the upper side of the inner cavity of both the constant-temperature preheating tank 3 and the dissolving tank 5, while the outlet is connected to the center of their bottoms, continuously providing hot water at a suitable temperature to ensure a stable ambient temperature during preheating and dissolution. During dissolution, the circulating hot water supply unit 2 continuously supplies hot water to the dissolving tank 5 to maintain a constant temperature, providing stable temperature conditions for the thawing and dissolution of medical fibrinogen, thus ensuring efficacy and safety. The dissolving tank 5 uses a magnetic shaker, mimicking the shaking of the medicine bottle by hand to accelerate dissolution, avoiding the shear force of traditional stirrers that damages the protein structure and protecting the efficacy. A dissolution monitor 14 is installed inside the magnetic shaker of the dissolving tank 5, corresponding to the middle of the medicine bottle, to monitor the dissolution status in real time, accurately determine the dissolution endpoint, standardize operations, reduce the impact of differences in operation among medical personnel, and improve efficacy and safety. The entire process is simple to operate and can complete the thawing and dissolution of medical fibrinogen more efficiently and stably, improving work efficiency and quality.

[0029] In this embodiment, preferably, a miniature circulating water pump 6 is installed at the top of the inner cavity of the circulating hot water supply unit 2. The output end of the miniature circulating water pump 6 pumps sterile water evenly downward through a long strip-shaped dispensing seat with multiple evenly distributed drip holes at the bottom. A PTC heater 7 is embedded in the middle of the inner cavity of the circulating hot water supply unit 2, and a water temperature sensor 29 is fixedly installed on the side wall of the constant temperature preheating tank 3 and the dissolving tank 5 corresponding to the middle of the medicine bottle. The miniature circulating water pump 6, the PTC heater 7, and the water temperature sensor 29 are all electrically connected to the PLC control terminal. The miniature circulating water pump 6 can more accurately pump sterile water evenly and dispersedly into the circulating hot water supply unit 2 through the long strip-shaped dispensing seat, and work with the PTC heater 7 to heat the water to ensure a constant water temperature. The water temperature sensor 29 installed on the side wall of the constant temperature preheating tank 3 and the dissolving tank 5 corresponding to the middle of the medicine bottle can monitor the water temperature in real time and feed the data back to the PLC control terminal. Based on the received water temperature data, the PLC control terminal intelligently adjusts the pumping speed of the micro circulating water pump 6 and the heating power of the PTC heater 7 to maintain the stability of the water temperature of the entire system. This provides a more precise and stable temperature environment for the thawing and dissolution of medical fibrinogen, further ensuring the efficacy and safety of the drug.

[0030] In this embodiment, preferably, an inlet nozzle 11 is fixedly connected to the upper side of the inner cavity of the constant temperature preheating tank 3 and the dissolving tank 5, and the inlet end of the micro circulating water pump 6 is connected to the inlet nozzle 11 through a pipe buried in the side wall of the insulated box 1. A preheating distribution plate 9 is fixedly connected to the bottom center of the constant temperature preheating tank 3, and a dissolving distribution plate 10 is fixedly connected to the bottom center of the dissolving tank 5. Both the preheating distribution plate 9 and the dissolving distribution plate 10 are hollow cylinders with multiple connecting holes evenly spaced on the side wall. The bottom center of the preheating distribution plate 9 and the dissolving distribution plate 10 is connected to the bottom center of the circulating hot water supply unit 2 through a medical hose. The upper end of the dissolving distribution plate 10 is fixedly connected to the bottom of the magnetic shaker. The inlet nozzle 11 on the upper side of the inner cavity of the constant temperature preheating tank 3 and the dissolving tank 5 facilitates the extraction of sterile water above the constant temperature preheating tank 3 and the dissolving tank 5, providing continuous water supply support for the circulating hot water supply unit 2. The miniature circulating water pump 6 is connected to the inlet 11 via a pipe embedded in the side wall of the insulated box 1, enabling efficient introduction of water into the circulation system. The design of the preheating dispensing tray 9 and the dissolving dispensing tray 10 ensures that hot water contacts the medicine bottles evenly and fully, guaranteeing a consistent ambient temperature for each bottle during both the preheating and dissolving stages, thus improving the effectiveness and efficiency of defrosting and dissolving. The upper end of the dissolving dispensing tray 10 is connected and fixed to the bottom of the magnetic shaker. This structure not only ensures a stable supply of hot water during dissolving but also makes the entire device more compact and efficient.

[0031] In this embodiment, preferably, the magnetic shaker includes a magnetic cylinder base 13. Multiple electromagnets 16 are embedded at equal intervals at the upper end of the magnetic cylinder base 13. Ferromagnetic adsorption blocks 17 are fixedly connected to the upper ends of the multiple electromagnets 16 via compression connecting springs 18. A medicine bottle shaker 15 is fixedly connected to the upper ends of the multiple ferromagnetic adsorption blocks 17, and the medicine bottle shaker 15 is concentrically placed with the magnetic cylinder base 13. A medicine bottle insertion hole is opened at the center of the medicine bottle shaker 15, and a rubber friction sleeve is fixedly connected to the inner wall of the insertion hole. When the magnetic shaker is energized, the multiple electromagnets 16 sequentially and cyclically generate magnetic force, sequentially attracting the corresponding ferromagnetic adsorption blocks 17 to move downwards, while the corresponding compression connecting springs 18 are compressed. When the current of the electromagnets 16 changes periodically, the ferromagnetic adsorption blocks 17 will reciprocate up and down under the elastic force of the compression connecting springs 18, thereby causing the medicine bottle shaker 15 to shake, achieving the effect of mimicking a human hand rotating and shaking a medicine bottle, and accelerating the dissolution process of medical fibrinogen. The medicine bottle holder 15 features a central medicine bottle insertion hole and a rubber friction sleeve fixedly connected to the inner wall, which better secures the medicine bottle, preventing it from slipping or being damaged during shaking and ensuring a smooth dissolution process. Simultaneously, this magnetically driven method avoids the shearing forces that can damage protein structures caused by traditional stirrers, maximizing the preservation of the efficacy of medical fibrinogen.

[0032] In this embodiment, preferably, the dissolution monitor 14 is installed at the bottom of the medicine bottle shaker 15 near the central medicine bottle insertion hole. The dissolution monitor 14 includes an auxiliary light source and an optical sensor arranged opposite each other, and the auxiliary light source and the optical sensor are set close to the medicine bottle inserted at the center of the medicine bottle shaker 15. The auxiliary light source emits light of a specific wavelength, and the optical sensor receives the intensity of the transmitted light passing through the solution. When the solution changes from a turbid state where the powder is not completely dissolved to a clear and transparent state where the powder is completely dissolved, the intensity of the transmitted light reaches a predetermined threshold. The PLC control terminal then controls the magnetic shaker to stop working and issues a prompt, thereby realizing the automatic judgment and shutdown of the dissolution endpoint and avoiding excessive stirring.

[0033] In this embodiment, preferably, the disposable pipetting mechanism includes a transfer frame 21. A docking slot 22 is provided on the front side of the transfer frame 21, and a filter-equipped transfer needle 23 is inserted into the docking slot 22. The filter-equipped transfer needle 23 is inserted into the docking slot 22, and then the infusion bottle is placed with its opening facing upwards, corresponding to the bottom of the filter-equipped transfer needle 23. Finally, the opening of a fully dissolved fibrin bottle is aligned with the upper end of the filter-equipped transfer needle 23 and inserted downwards. Simultaneously, the bottom of the filter-equipped transfer needle 23 is inserted into the infusion bottle. The high pressure inside the fibrin bottle opening forces out the dissolved fibrin solution, allowing the solution to be filtered through the filter-equipped transfer needle 23 before entering the infusion bottle, facilitating subsequent infusion. The design of the docking slot 22 allows for more precise matching of the opening of the shaken and dissolved bottle, ensuring accurate positioning of the filter-equipped transfer needle 23 when inserted into the bottle, avoiding liquid leakage or contamination due to positional deviations. This design makes the disposable pipetting mechanism more convenient and efficient during operation, reducing errors and risks that may arise from manual operation.

[0034] In this embodiment, preferably, the infusion dosing device 4 is disposed between the constant temperature preheating tank 3 and the dissolving tank 5, and a square slot is provided on the rear side of the infusion dosing device 4. A gas spring telescopic rod sleeve 19 is movably inserted into the square slot on the rear side of the infusion dosing device 4. A piston inner rod 20 is movably inserted into the bottom of the gas spring telescopic rod sleeve 19. The bottom of the piston inner rod 20 is fixedly connected to the bottom of the square slot on the rear side of the infusion dosing device 4. An ejection spring is provided between the upper end of the piston inner rod 20 and the top of the inner cavity of the gas spring telescopic rod sleeve 19. The upper end of the gas spring telescopic rod sleeve 19 is fixedly connected to the rear end of the transfer frame 21, and the top vent valve 24 of the gas spring telescopic rod sleeve 19 is provided through the transfer frame 21. When the transfer frame 21 performs a liquid transfer operation, the vent valve 24 is opened through the gas spring telescopic rod sleeve 19 and the piston inner rod 20, and the gas spring telescopic rod sleeve 19 and the piston inner rod 20 extend under the return elasticity of the ejection spring. When the transfer frame 21 is pressed down to insert the filter transfer needle 23 into the infusion bottle, the gas spring telescopic rod sleeve 19 moves downward along the piston inner rod 20, compressing the ejector spring and providing guidance for the transfer frame 21 to rise and fall. When the device is stored, the gas spring telescopic rod sleeve 19 is pressed down to the end of its stroke, and then the vent valve 24 is closed, so that the gas spring telescopic rod sleeve 19 and the piston inner rod 20 remain in a contracted state under the action of air pressure. This not only facilitates the storage of the transfer frame 21 and reduces the space occupied, but also allows the gas spring telescopic rod sleeve 19 and the piston inner rod 20 to quickly return to the working state when the vent valve 24 is opened for the next use.

[0035] In this embodiment, preferably, the filter transfer needle 23 is a double-ended needle with a hollow flat round piece fixed in the middle that matches the docking groove 22. A filter screen is fixedly connected to the center of the hollow flat round piece's inner cavity. The size of the docking groove 22 matches the mouth of the medicine bottle, and a through-hole is provided at the bottom center of the docking groove 22. This unique structure of the filter transfer needle 23 allows it to play multiple roles during liquid transfer. The double-ended needle design facilitates bidirectional liquid flow. The hollow flat round piece fixed in the middle not only provides stable support for the connection between the filter transfer needle 23 and the docking groove 22, but also effectively intercepts impurities or undissolved particles that may be generated during dissolution through the filter screen fixedly connected in the center of the inner cavity. This ensures that the dissolved liquid injected into the medicine bottle is pure and uncontaminated, guaranteeing the safety of subsequent infusions. The size of the docking groove 22 matches the mouth of the medicine bottle, ensuring the accuracy and stability of the filter transfer needle 23 when inserted into the medicine bottle, avoiding liquid leakage or contamination problems caused by positional deviations. Meanwhile, the through-hole at the bottom center of the docking slot 22 provides a smooth channel for the insertion of the filter transfer needle 23, further improving the convenience and efficiency of pipetting operations.

[0036] In this embodiment, preferably, the upper end of the infusion dosing device 4 is provided with multiple storage slots 27 at equal intervals, and a storage cylinder 28 is movably inserted into the storage slot 27. The storage cylinder 28 is a hollow cylinder with an opening on the side wall, and a disposable transfer needle with filter is placed inside the storage cylinder 28.

[0037] Multiple storage slots 27 on the upper part of the infusion dispenser 4 provide a stable and orderly storage location for the storage cylinder 28, facilitating quick access by medical staff. The movable plug-in design makes the installation and removal of the storage cylinder 28 easy and simple, improving work efficiency. The hollow cylindrical shape of the storage cylinder 28, with its side openings, is not only structurally simple but also allows for easy observation of the internal storage of the filter transfer needles. Multiple disposable filter transfer needles 23 are placed inside the storage cylinder, ensuring hygiene and safety for each use, avoiding the risk of cross-infection, and enabling centralized management to prevent the filter transfer needles 23 from scattering or being lost, thus ensuring the standardization and reliability of medical procedures.

[0038] In this embodiment, preferably, an insulated box cover 25 is fixedly connected to the upper back side of the insulated box body 1, and a sealing pressure plate 26 is fixedly connected to the inner side of the insulated box cover 25 corresponding to the positions of the constant temperature preheating tank 3 and the dissolution tank 5. A PLC control terminal is embedded inside the insulated box cover 25. The design of the insulated box cover 25 not only provides good insulation for the entire device, reducing heat loss and energy consumption, but also effectively prevents external dust and impurities from entering the device, ensuring the cleanliness of the environment for the thawing and dissolution of medical fibrinogen. The sealing pressure plate 26, fixedly connected to the inner side of the insulated box cover 25 corresponding to the positions of the constant temperature preheating tank 3 and the dissolution tank 5, can tightly fit against the constant temperature preheating tank 3 and the dissolution tank 5 when the insulated box cover 25 is closed, further enhancing the sealing performance and ensuring the stability of the internal temperature of the device. The PLC control terminal embedded in the insulated box cover 25 serves as the intelligent control core of the entire device. It can centrally receive and process data from various sensors, such as water temperature information from the water temperature sensor 29. Based on preset programs, it can more accurately adjust the pumping speed of the micro circulating water pump 6, the heating power of the PTC heater 7, and the working status of the magnetic shaker, thereby achieving intelligent control of the device's operating parameters. This enables the entire medical fibrinogen-specific constant temperature thawing and dissolution device to operate more efficiently, stably, and safely, providing a reliable guarantee for the thawing and dissolution of medical fibrinogen.

[0039] The above description of the disclosed embodiments enables those skilled in the art to make or use the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A medical fibrinogen-specific constant-temperature thawing and dissolving device, characterized in that: The utility model provides a kind of medical infusion device, including heat preservation box (1), and integrated in heat preservation box (1) circulating hot water supplier (2), constant temperature preheating groove (3), infusion medicine device (4) and dissolving groove (5), circulating hot water supplier (2) is arranged in heat preservation box (1) inner chamber one side, the porous placing rack (12) is placed in constant temperature preheating groove (3), and disposable pipetting mechanism is provided on infusion medicine device (4), the inner chamber center of dissolving groove (5) is equipped with magnetic shaker, and the inner corresponding medicine bottle middle part of magnetic shaker is equipped with dissolving monitor (14), the inner chamber bottom of constant temperature preheating groove (3) and dissolving groove (5) is equipped with sterile water, and sterile water submerges porous placing rack (12) and magnetic shaker, circulating hot water supplier (2) inlet end is respectively communicated constant temperature preheating groove (3) and the inner chamber upper side of dissolving groove (5), and circulating hot water supplier (2) outlet end is respectively communicated constant temperature preheating groove (3) and the bottom center of dissolving groove (5).

2. The medical fibrinogen special constant temperature thawing and dissolving device according to claim 1, characterized in that: The inner chamber top of circulating hot water supplier (2) is equipped with micro circulating water pump (6), and the output end of micro circulating water pump (6) is downwardly and evenly dispersed pumped sterile water through the long strip-shaped distribution seat that is uniformly provided with a plurality of liquid drop holes in bottom, the inner chamber middle part of circulating hot water supplier (2) is embedded with PTC heater (7), and water temperature sensor (29) is fixedly installed on the side wall corresponding medicine bottle middle part of constant temperature preheating groove (3) and dissolving groove (5), and micro circulating water pump (6), PTC heater (7) and water temperature sensor (29) are all electrically connected with PLC control terminal.

3. The medical fibrinogen special constant temperature thawing and dissolving device according to claim 2, characterized in that: The inner chamber upper side of constant temperature preheating groove (3) and dissolving groove (5) is fixedly connected with inlet nozzle (11), and the inlet end of micro circulating water pump (6) is communicated with inlet nozzle (11) through the pipeline embedded in the side wall of heat preservation box (1), the bottom center of constant temperature preheating groove (3) is fixedly connected with preheating distribution disc (9), and the bottom center of dissolving groove (5) is fixedly connected with dissolving distribution disc (10), the preheating distribution disc (9) and dissolving distribution disc (10) are all hollow cylinders with a plurality of communication holes being equidistantly provided in the side wall, and the bottom center of preheating distribution disc (9) and dissolving distribution disc (10) is connected with the bottom center of circulating hot water supplier (2) through medical hose, and the upper end of dissolving distribution disc (10) is fixedly connected with the bottom of magnetic shaker.

4. The medical fibrinogen special constant temperature thawing and dissolving device according to claim 1, characterized in that: The magnetic shaker includes magnetic cylinder base (13), a plurality of electromagnets (16) are equidistantly embedded in the upper end of magnetic cylinder base (13), and the upper end of a plurality of electromagnets (16) is fixedly connected with ferromagnetic adsorption block (17) through compression connecting spring (18), the upper end of a plurality of ferromagnetic adsorption blocks (17) is fixedly connected with medicine bottle rocker (15), and medicine bottle rocker (15) is concentrically placed with magnetic cylinder base (13), medicine bottle rocker (15) is provided with medicine bottle insertion hole in the center, and the inner wall of insertion hole is fixedly connected with rubber friction sleeve.

5. The medical fibrinogen special constant temperature thawing and dissolving device according to claim 4, characterized in that: The dissolution monitor (14) is installed at the bottom of the medicine bottle cradle (15) near the central medicine bottle insertion hole, the dissolution monitor (14) comprises an auxiliary light source and an optical sensor arranged oppositely, and the auxiliary light source and the optical sensor are arranged close to the medicine bottle inserted in the center of the medicine bottle cradle (15).

6. The medical fibrinogen special constant temperature thawing and dissolving device according to claim 1, characterized in that: The disposable pipetting mechanism comprises a transfer frame (21), the front side of the transfer frame (21) is provided with a docking clamping groove (22), and a filtering transfer needle (23) is inserted into the docking clamping groove (22).

7. The medical fibrinogen special constant temperature thawing and dissolving device according to claim 6, characterized in that: The infusion medicine adding device (4) is arranged between the constant-temperature preheating tank (3) and the dissolution tank (5), the rear side of the infusion medicine adding device (4) is provided with a square insertion slot, a gas spring telescopic rod sleeve (19) is movably inserted into the square insertion slot of the rear side of the infusion medicine adding device (4), a piston inner rod (20) is movably inserted into the bottom of the gas spring telescopic rod sleeve (19), the bottom of the piston inner rod (20) is fixedly connected with the bottom of the square insertion slot of the rear side of the infusion medicine adding device (4), a push spring is arranged between the upper end of the piston inner rod (20) and the top of the inner cavity of the gas spring telescopic rod sleeve (19), the upper end of the gas spring telescopic rod sleeve (19) is fixedly connected with the rear side of the transfer frame (21), and a deflation valve (24) arranged at the top of the gas spring telescopic rod sleeve (19) penetrates through the transfer frame (21).

8. The medical fibrinogen special constant temperature thawing and dissolving device according to claim 6, characterized in that: The filtering transfer needle (23) is a double-end needle with a hollow flat circular sheet fixed at the middle portion and matched with the docking clamping groove (22), and a filter screen is fixedly connected in the inner cavity of the hollow flat circular sheet, the size of the docking clamping groove (22) is matched with the bottle opening of the medicine bottle, and a through insertion hole is formed in the bottom center of the docking clamping groove (22).

9. The medical fibrinogen special constant temperature thawing and dissolving device according to claim 6, characterized in that: A plurality of storage insertion slots (27) are formed at the upper end of the infusion medicine adding device (4) at equal intervals, a storage cylinder (28) is movably inserted into each storage insertion slot (27), the storage cylinder (28) is a hollow cylinder with an open side wall, and a disposable filtering transfer needle (23) is placed in the storage cylinder (28).

10. The medical fibrinogen special constant temperature thawing and dissolving device according to claim 1, characterized in that: The upper end of the heat preservation box body (1) is fixedly connected with a heat preservation box cover (25), the inner side of the heat preservation box cover (25) is fixedly connected with a sealing pressing plate (26) corresponding to the positions of the constant-temperature preheating tank (3) and the dissolution tank (5), and a PLC control terminal is embedded in the heat preservation box cover (25).

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