Self-emulsifying full-wave-band compound micro-emulsion capsule sun-screening agent as well as preparation method and application thereof

Abstract

The invention relates to the technical field of skin care products, and particularly discloses a self-emulsifying full-wave-band compound micro-emulsion capsule sun-screening agent and a preparation method thereof. The preparation method comprises the following steps: 1, mixing an oily solvent, ethylhexyl triazinone, diethylaminohydroxybenzoyl hexyl benzoate and cresol trozole trisiloxane to obtain an oil phase; 2, mixing a water-based solvent, a humectant and methylene bis-benzotriazolyl tetramethyl butyl phenol to obtain a water phase; 3, mixing the oil phase, polyglycerol-6 laurate, PEG-20 (Polyethylene Glycol-20) glyceryl triisostearate, polyethylene glycol-30 dipolyhydroxystearate and hydrogenated lecithin, so as to obtain a pretreated oil phase; 4, adding the pretreated oil phase into the water phase to obtain a mixed phase; 5, adding gelatin, sodium alginate and glutaraldehyde to obtain a composite wall material microcapsule system; and 6, adding a preservative to obtain the sun-screening agent. The sunscreen composition has the advantages that the sunscreen effect is more comprehensive, and the stability of the sunscreen composition is improved on the premise of reducing the use amount of the emulsifier to reduce skin irritation.

Description

Technical Field

[0001] This invention relates to the field of skincare products, and in particular to a self-emulsifying full-spectrum compound microemulsion sunscreen and its preparation method. Background Technology

[0002] As people pay increasing attention to skin health and beauty, sunscreen products have become an important part of daily skincare. Ultraviolet (UV) radiation from sunlight is divided into UVA (long-wave ultraviolet radiation, wavelength 320-400nm) and UVB (medium-wave ultraviolet radiation, wavelength 280-320nm). UVA can penetrate the dermis, causing tanning and photoaging; UVB mainly affects the epidermis, causing sunburn, erythema, and other skin problems.

[0003] While current sunscreens on the market can achieve some sun protection by adding ingredients that absorb or block ultraviolet rays, existing sunscreens do not provide comprehensive protection against all UV wavelengths, only protecting against either UVA or UVB. Furthermore, traditional sunscreens often require large amounts of emulsifiers to achieve a water-oil phase mixture, but excessive emulsifiers can irritate the skin and cause allergic reactions. Conversely, reducing the amount of emulsifier can lead to poor stability, causing issues such as layering and deterioration during storage or use, affecting sun protection effectiveness and product lifespan. Therefore, there is still room for improvement. Summary of the Invention

[0004] In order to make sun protection more comprehensive and improve the stability of sunscreen agents while reducing the amount of emulsifiers used to reduce skin irritation, this application provides a self-emulsifying full-spectrum compound microemulsion capsule sunscreen agent and its preparation method.

[0005] In a first aspect, this application provides a method for preparing a self-emulsifying full-spectrum compound microemulsion sunscreen, employing the following technical solution: A method for preparing a self-emulsifying, full-spectrum, compound microemulsion sunscreen agent includes the following steps: Step 1): Heat the oily solvent to 55-65℃ and stir continuously at a speed of 180-220 r / min. Then add ethylhexyl triazine, diethylamino hydroxybenzoyl hexyl benzoate, and cresoltrazol trisiloxane. Stir at a speed of 180-220 r / min for 20-30 min to obtain the oil phase. Step 2): Mix the aqueous solvent and humectant, heat to 55-65℃, stir at 150-200 r / min for 15-20 min, then add methylenebis-benzotriazolyltetramethylbutyrol, stir at 150-200 r / min for 10-15 min, adjust the pH to 5.0-5.5 to obtain the aqueous phase; Step 3): Add polyglycerol-6 laurate, PEG-20 glycerol triisostearate, polyethylene glycol-30 dimer hydroxystearate, and hydrogenated lecithin to the oil phase. Stir at 250-300 r / min for 10-15 min to obtain the pretreated oil phase. Step 4) Slowly add the pretreated oil phase to the aqueous phase at a rate of 1-2 mL / min. During the addition, turn on the homogenizer and set the homogenizer speed to 3500-4000 r / min. After the addition is complete, homogenize for 25-30 min to obtain the mixed phase. Step 5) Cool the mixed phase to 35-40℃, then add gelatin to the mixed phase, stir at 150-200 r / min for 15-20 min, then slowly add sodium alginate aqueous solution and stir for 20-25 min, then add glutaraldehyde aqueous solution dropwise and heat to 45-50℃, stir and cure for 30-40 min to obtain composite wall material microcapsule system; Step 6) Add preservatives to the composite wall material microcapsule system, mix evenly, and adjust the pH to 5.0-5.5 to obtain a compound microemulsion capsule sunscreen agent derived from emulsification of the entire wavelength range.

[0006] By adopting the above technical solution, the combination of ethylhexyl triazine ketone, diethylamino hydroxybenzoyl hexyl benzoate, cresoltrazolium trisiloxane, and methylene bis-benzotriazolyl tetramethylbutyrolactone can effectively absorb UVB and UVA ultraviolet rays, making the sun protection effect more comprehensive. The combination of polyglycerol-6 laurate, PEG-20 glycerol triisostearate, polyethylene glycol-30 dimer hydroxystearate, and hydrogenated lecithin forms a special emulsion system. Combined with the microcapsule wall material formed by gelatin, sodium alginate aqueous solution, and glutaraldehyde aqueous solution, the stability of the sunscreen agent can be greatly improved. A small amount of emulsifier is required to achieve long-lasting stability, making the sunscreen agent of stable quality. At the same time, the sunscreen agent has lower irritation, higher safety, and is less likely to cause damage to the skin.

[0007] Preferably, in step 1), the oily solvent is a compound of C12-15 alcohol benzoate and caprylic / capric triglyceride, wherein the mass ratio of C12-15 alcohol benzoate to caprylic / capric triglyceride is 14-16:2.5-3.5.

[0008] By adopting the above technical solution and specifically selecting C12-15 benzoyl alcohol and caprylic / capric triglycerides, the solubility of oily components is high, allowing them to work together better and exert a better sun protection effect.

[0009] Preferably, in step 1), the mass ratio of the oily solvent, ethylhexyl triazine ketone, diethylamino hydroxybenzoyl hexyl benzoate, and cresoltrazol trisiloxane is 16.5-19.5: 7.5-8.5: 5.5-6.5: 5.5-6.5.

[0010] By adopting the above technical solution, the synergistic effect of ethylhexyl triazine ketone, diethylamino hydroxybenzoyl hexyl benzoate, and cresoltrazol trisiloxane is better, the synergistic effect is more significant, and the sun protection effect is better.

[0011] Preferably, in step 2), the mass ratio of the aqueous solvent, the humectant, and the methylenebis-benzotriazolyltetramethylbutyrolactone is 36.3-19.3:7.05-9.15:3.5-4.5, the aqueous solvent is deionized water, and the humectant is a compound of glycerin and sodium hyaluronate, wherein the mass ratio of glycerin and sodium hyaluronate in the humectant is 7-9:0.05-0.15.

[0012] By adopting the above technical solution and specifically selecting glycerin and sodium hyaluronate, the moisturizing effect is better, and the sunscreen is less likely to cause dryness after use, thus improving the user experience of the sunscreen.

[0013] Preferably, in step 3), the mass ratio of oil phase, polyglycerol-6 laurate, PEG-20 glycerol triisostearate, polyethylene glycol-30 dihydroxystearate, and hydrogenated lecithin is 35-41:9.5-10.5:2-2.8:0.4-0.6:1.5-2.5.

[0014] By adopting the above technical solution and specifically selecting the mass ratio of oil phase, polyglycerol-6 laurate, PEG-20 glycerol triisostearate, polyethylene glycol-30 dimer hydroxystearate, and hydrogenated lecithin, the emulsification stability is higher, the sunscreen agent is more stable, and it is less prone to stratification.

[0015] Preferably, in step 4), the mass ratio of the pretreated oil phase to the aqueous phase is 48.4-57.4:32.95-46.85.

[0016] By adopting the above technical solution and specifically selecting the ratio of pretreated oil phase and water phase, the components can be better combined in a specific ratio. The synergistic effect of methylene bis-benzotriazolyl tetramethylbutyrol, ethylhexyl triazine ketone, diethylamino hydroxybenzoyl hexyl benzoate, and cresoltrazol trisiloxane is better, the sun protection effect is more significant, the amount of emulsifier is lower, and the sunscreen agent has higher stability.

[0017] Preferably, in step 5), the mass ratio of the mixed phase, gelatin, sodium alginate aqueous solution, and glutaraldehyde aqueous solution is 90.35-95.25: 2.5-3.5: 1.5-2.5: 0.5-1.5; The concentration of the sodium alginate aqueous solution is 20 g / L; The mass concentration of the glutaraldehyde aqueous solution is 0.5%.

[0018] By adopting the above technical solution and by specifically selecting the mass ratio of gelatin, sodium alginate aqueous solution, and glutaraldehyde aqueous solution, the prepared microcapsules can better cooperate with the emulsifier, the microcapsules are less prone to rupture, and the sunscreen agent has better stability.

[0019] Preferably, in step 6), the mass ratio of the composite wall material microcapsule system to the preservative is 97.85-99.75:0.2-2, and the preservative is a compound of p-hydroxyacetophenone and 1,2-hexanediol, with a mass ratio of p-hydroxyacetophenone to 1,2-hexanediol of 0.1-1:0.1-1.

[0020] By adopting the above technical solution and selecting p-hydroxyacetophenone and 1,2-hexanediol, the anti-corrosion effect is better, the irritation is lower, and the quality of the sunscreen is better.

[0021] Secondly, this application provides a self-emulsifying, full-spectrum compound microemulsion sunscreen agent, employing the following technical solution: A self-emulsifying full-spectrum compound microemulsion sunscreen is prepared by the above-mentioned preparation method of the self-emulsifying full-spectrum compound microemulsion sunscreen.

[0022] By adopting the above technical solution, the resulting sunscreen has a more comprehensive sun protection effect, and the sunscreen has better stability, is less prone to stratification, and has better product quality.

[0023] Thirdly, this application provides an application of a self-emulsifying, full-spectrum compound microemulsion sunscreen agent, employing the following technical solution: An application of the above-mentioned self-emulsifying full-spectrum compound microemulsion capsule sunscreen agent, wherein the self-emulsifying full-spectrum compound microemulsion capsule sunscreen agent is added to a sunscreen product formulation to prepare a sunscreen product, wherein the mass content of the self-emulsifying full-spectrum compound microemulsion capsule sunscreen agent in the sunscreen product is 10-20%.

[0024] By adopting the above technical solution, the resulting sunscreen product has a good sun protection effect.

[0025] In summary, this application has the following beneficial effects: 1. Because this application uses a compound of ethylhexyl triazine ketone, diethylamino hydroxybenzoyl hexyl benzoate, cresoltrazolium trisiloxane, and methylene bis-benzotriazolyl tetramethylbutyrolactone, it can effectively absorb UVB and UVA ultraviolet rays, making the sun protection effect more comprehensive. Through the compound of polyglycerol-6 laurate, PEG-20 glycerol triisostearate, polyethylene glycol-30 dimer hydroxystearate, and hydrogenated lecithin, a special emulsification system is formed. Combined with the microcapsule wall material formed by gelatin, sodium alginate aqueous solution, and glutaraldehyde aqueous solution, the stability of the sunscreen is greatly improved. A small amount of emulsifier is used to achieve long-lasting stability, making the sunscreen quality stable. At the same time, the sunscreen has lower irritation, higher safety, and is less likely to damage the skin.

[0026] 2. In this application, the preferred method is to select the specific mass ratio of the oil phase, polyglycerol-6 laurate, PEG-20 glycerol triisostearate, polyethylene glycol-30 dihydroxystearate, and hydrogenated lecithin to achieve higher emulsification stability, better stability of the sunscreen agent, and less stratification. Attached Figure Description

[0027] Figure 1 This is a transmission electron microscope image of Example 1.

[0028] Figure 2 This is a transmission electron microscope image of Example 2.

[0029] Figure 3 This is a transmission electron microscope image of Example 3.

[0030] Figure 4 This is a transmission electron microscope image of Comparative Example 1.

[0031] Figure 5 This is a transmission electron microscope image of Comparative Example 2.

[0032] Figure 6 This is a transmission electron microscope image of Comparative Example 3.

[0033] Figure 7 This is a transmission electron microscope image of Comparative Example 4.

[0034] Figure 8 This is a transmission electron microscope image of Comparative Example 5. Detailed Implementation

[0035] The present application will be further described in detail below with reference to the embodiments. Example 1

[0036] A method for preparing a self-emulsifying, full-spectrum, compound microemulsion sunscreen, characterized by comprising the following steps: Step 1): Add 14g of C12-15 alcohol benzoate and 2.5g of caprylic / capric triglyceride to the oil phase pot, heat to 55℃, and stir continuously at 180r / min. Then add 7.5g of ethylhexyl triazine ketone, 5.5g of diethylamino hydroxybenzoyl hexyl benzoate and 5.5g of cresoltrazol trisiloxane, and stir at 180r / min for 20min to obtain the oil phase.

[0037] Step 2): Add 36.3g water, 7g glycerol, and 0.05g sodium hyaluronate to the aqueous phase pot, heat to 55℃, stir at 150r / min for 15min, then add 3.5g methylenebis-benzotriazolyltetramethylbutyrol, stir at 150r / min for 10min, add citric acid to adjust the pH to 5.0, and obtain the aqueous phase.

[0038] Step 3): Add 9.5g polyglycerol-6 laurate, 2g PEG-20 glycerol triisostearate, 0.46g polyethylene glycol-30 dimer hydroxystearate, and 1.5g hydrogenated lecithin to the oil phase. Stir at 250r / min for 10min to obtain the pretreated oil phase.

[0039] Step 4): Slowly add the pretreated oil phase to the aqueous phase at a rate of 1 mL / min. During the addition, turn on the homogenizer at a speed of 3500 r / min. After the addition is complete, homogenize for 25 min to obtain the mixed phase.

[0040] Step 5): Cool the mixed phase to 35°C, then add 2.5g of gelatin to the mixed phase, stir at 150r / min for 15min, then slowly add 1.5g of sodium alginate aqueous solution with a concentration of 20g / L, stir at 150r / min for 20min, then add 0.5g of glutaraldehyde aqueous solution with a mass concentration of 0.5%, and heat to 45°C, stir at 150r / min for 30min to cure, thus obtaining the composite wall material microcapsule system.

[0041] Step 6): Add 0.1g p-hydroxyacetophenone and 0.1g 1,2-hexanediol to the composite wall material microcapsule system. Stir at 150r / min for 10min until the mixture is homogeneous. Add citric acid to adjust the pH to 5.0. Stir at 150r / min for 5min to obtain the emulsified full-wavelength compound microemulsion capsule sunscreen. Example 2

[0042] A method for preparing a self-emulsifying, full-spectrum, compound microemulsion sunscreen, characterized by comprising the following steps: Step 1): Add 15g of C12-15 alcohol benzoate and 3g of caprylic / capric triglyceride to the oil phase pot, heat to 60℃, and stir continuously at 200r / min. Then add 8g of ethylhexyl triazine ketone, 6g of diethylamino hydroxybenzoyl hexyl benzoate and 6g of cresoltrazol trisiloxane, and stir at 200r / min for 25min to obtain the oil phase.

[0043] Step 2): Add 27.8g of water, 8g of glycerol, and 0.1g of sodium hyaluronate to the aqueous phase pot, heat to 60℃, stir at 180r / min for 18min, then add 4g of methylenebis-benzotriazolyltetramethylbutyrol, stir at 180r / min for 13min, add citric acid to adjust the pH to 5.0, and obtain the aqueous phase.

[0044] Step 3): Add 10g polyglycerol-6 laurate, 2.5g PEG-20 glycerol triisostearate, 0.5g polyethylene glycol-30 dimer hydroxystearate, and 2g hydrogenated lecithin to the oil phase. Stir at 280r / min for 13min to obtain the pretreated oil phase.

[0045] Step 4): The pretreated oil phase is slowly added dropwise to the aqueous phase at a rate of 1.5 mL / min. During the addition, a homogenizer is turned on at a speed of 3800 r / min. After the addition is complete, the homogenizer is homogenized for 28 min to obtain the mixed phase.

[0046] Step 5): Cool the mixed phase to 38°C, then add 3g of gelatin to the mixed phase, stir at 180r / min for 18min, then slowly add 2g of sodium alginate aqueous solution with a concentration of 20g / L, stir at 180r / min for 23min, then add 1g of glutaraldehyde aqueous solution with a mass concentration of 0.5%, and heat to 48°C, stir at 180r / min for 35min to cure, thus obtaining the composite wall material microcapsule system.

[0047] Step 6) Add 0.5g p-hydroxyacetophenone and 0.5g 1,2-hexanediol to the composite wall material microcapsule system, stir at 180r / min for 13min, mix evenly, add citric acid to adjust pH to 5.0, stir at 180r / min for 5min, and obtain the emulsified full-wavelength compound microemulsion capsule sunscreen agent. Example 3

[0048] A method for preparing a self-emulsifying, full-spectrum, compound microemulsion sunscreen, characterized by comprising the following steps: Step 1): Add 16g of C12-15 alcohol benzoate and 3.5g of caprylic / capric triglyceride to the oil phase pot, heat to 65℃, and stir continuously at 220r / min. Then add 8.5g of ethylhexyl triazine ketone, 6.5g of diethylamino hydroxybenzoyl hexyl benzoate, and 6.5g of cresoltrazol trisiloxane, and stir at 220r / min for 30min to obtain the oil phase.

[0049] Step 2): Add 19.3g of water, 9g of glycerol, and 0.15g of sodium hyaluronate to the aqueous phase pot, heat to 65℃, stir at 200r / min for 20min, then add 4.5g of methylenebis-benzotriazolyltetramethylbutyrol, stir at 200r / min for 15min, add citric acid to adjust the pH to 5.5, and obtain the aqueous phase.

[0050] Step 3): Add 10.5g polyglycerol-6 laurate, 2.8g PEG-20 glycerol triisostearate, 0.6g polyethylene glycol-30 dimer hydroxystearate, and 2.5g hydrogenated lecithin to the oil phase. Stir at 300r / min for 15min to obtain the pretreated oil phase.

[0051] Step 4) The pretreated oil phase is slowly added dropwise to the aqueous phase at a rate of 2 mL / min. During the addition, the homogenizer is turned on at a speed of 4000 r / min. After the addition is completed, the homogenizer is homogenized for 30 min to obtain the mixed phase.

[0052] Step 5): Cool the mixed phase to 40°C, then add 3.5g of gelatin to the mixed phase, stir at 200r / min for 20min, then slowly add 2.5g of sodium alginate aqueous solution with a concentration of 20g / L, stir at 200r / min for 25min, then add 1.5g of glutaraldehyde aqueous solution with a mass concentration of 0.5%, and heat to 50°C, stir at 200r / min for 40min to cure, thus obtaining the composite wall material microcapsule system.

[0053] Step 6): Add 1g of p-hydroxyacetophenone and 1g of 1,2-hexanediol to the composite wall material microcapsule system. Stir at 200r / min for 15min until well mixed. Add citric acid to adjust the pH to 5.5. Stir at 200r / min for 5min to obtain the emulsified full-spectrum compound microemulsion sunscreen.

[0054] Comparative Example 1 A method for preparing a self-emulsifying full-spectrum compound microemulsion capsule sunscreen agent differs from Example 2 only in that: Polyglycerol-6 laurate was replaced with an equal amount of polyglycerol-3 octanoate.

[0055] Comparative Example 2 A method for preparing a self-emulsifying full-spectrum compound microemulsion capsule sunscreen agent differs from Example 2 only in that: Polyglycerol-10 laurate was used to replace PEG-20 glycerol triisostearate in an equal amount.

[0056] Comparative Example 3 A method for preparing a self-emulsifying full-spectrum compound microemulsion capsule sunscreen agent differs from Example 2 only in that: Sorbitan isostearate was used to replace polyethylene glycol-30 dihydroxystearate in an equal amount.

[0057] Comparative Example 4 A method for preparing a self-emulsifying full-spectrum compound microemulsion capsule sunscreen agent differs from Example 2 only in that: Soybean lecithin was used to replace hydrogenated lecithin in an equal amount.

[0058] Comparative Example 5 A method for preparing a self-emulsifying full-spectrum compound microemulsion capsule sunscreen agent differs from Example 2 only in that: Polyglycerol-3 octanoate was used to replace polyglycerol-6 laurate in equal amounts; polyglycerol-10 laurate was used to replace PEG-20 glycerol triisostearate in equal amounts; sorbitan isostearate was used to replace polyethylene glycol-30 dihydroxystearate in equal amounts; and soybean lecithin was used to replace hydrogenated lecithin in equal amounts.

[0059] Experiment 1 The self-emulsifying full-spectrum compound microemulsion sunscreens of each embodiment and comparative example were injected into test tubes, sealed, and placed in a centrifuge at 3000 r / min for 25 min. The sunscreens in the test tubes were observed to see if they showed stratification. Then, samples were taken and observed by transmission electron microscopy (TEM) to see if the microcapsules of the sunscreens were ruptured.

[0060] Detailed experimental data for Experiment 1 are shown in Table 1 and Figure 1-8 .

[0061] Experiment 2 The irritation scores (IS) of the self-emulsifying full-spectrum compound microemulsion capsule sunscreens in each example and comparative example were tested according to SNT 2329-2009, "Cosmetic eye irritation / corrosiveness test for chicken embryo chorioallantoic membrane".

[0062] IS < 1: Non-irritating.

[0063] 1 ≤ IS < 5: Mild irritation.

[0064] 5 ≤ IS < 9: Moderate irritation.

[0065] IS≥10: Strong irritant / corrosive.

[0066] Table 1

[0067] According to Table 1 and Figure 1-8 It was found that the sunscreens in each embodiment did not exhibit stratification after centrifugation, and the microcapsule particles remained intact without breakage. This demonstrates that the emulsion system composed of polyglycerol-6 laurate, PEG-20 glycerol triisostearate, polyethylene glycol-30 dimer hydroxystearate, and hydrogenated lecithin in each embodiment, along with the microcapsule wall material composed of gelatin, sodium alginate, and glutaraldehyde, has a good synergistic effect. This significantly improves the overall stability of the sunscreen and also enhances the stability of the microcapsule wall material through the emulsion system. As a result, the sunscreen can maintain its quality stability even under extreme conditions, significantly reducing the likelihood of stratification that renders the sunscreen unusable. Furthermore, the emulsifier dosage in each embodiment is low, resulting in a low irritation score and minimizing the risk of skin allergies or other discomfort.

[0068] While each ratio also has lower irritation, the emulsion system has poor stability, which makes it prone to stratification and makes it difficult to protect the microcapsules, causing the microcapsules to rupture easily. This results in poor stability of the sunscreen agent, making it prone to stratification and rendering it unusable.

[0069] This specific embodiment is merely an explanation of this application and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of the claims of this application.

Claims

1. A method for preparing a self-emulsifying, full-spectrum, compound microemulsion sunscreen, characterized in that: Includes the following steps: Step 1): Heat the oily solvent to 55-65℃ and stir continuously at a speed of 180-220 r / min. Then add ethylhexyl triazine, diethylamino hydroxybenzoyl hexyl benzoate, and cresoltrazol trisiloxane. Stir at a speed of 180-220 r / min for 20-30 min to obtain the oil phase. Step 2): Mix the aqueous solvent and humectant, heat to 55-65℃, stir at 150-200 r / min for 15-20 min, then add methylenebis-benzotriazolyltetramethylbutyrol, stir at 150-200 r / min for 10-15 min, adjust the pH to 5.0-5.5 to obtain the aqueous phase; Step 3): Add polyglycerol-6 laurate, PEG-20 glycerol triisostearate, polyethylene glycol-30 dimer hydroxystearate, and hydrogenated lecithin to the oil phase. Stir at 250-300 r / min for 10-15 min to obtain the pretreated oil phase. Step 4) Slowly add the pretreated oil phase to the aqueous phase at a rate of 1-2 mL / min. During the addition, turn on the homogenizer and set the homogenizer speed to 3500-4000 r / min. After the addition is complete, homogenize for 25-30 min to obtain the mixed phase. Step 5) Cool the mixed phase to 35-40℃, then add gelatin to the mixed phase, stir at 150-200 r / min for 15-20 min, then slowly add sodium alginate aqueous solution and stir for 20-25 min, then add glutaraldehyde aqueous solution dropwise and heat to 45-50℃, stir and cure for 30-40 min to obtain composite wall material microcapsule system; Step 6) Add preservatives to the composite wall material microcapsule system, mix evenly, and adjust the pH to 5.0-5.5 to obtain a compound microemulsion capsule sunscreen agent derived from emulsification of the entire wavelength range.

2. The method for preparing a self-emulsifying full-spectrum compound microemulsion sunscreen agent according to claim 1, characterized in that: In step 1), the oily solvent is a compound of C12-15 alcohol benzoate and caprylic / capric triglyceride, wherein the mass ratio of C12-15 alcohol benzoate and caprylic / capric triglyceride is 14-16:2.5-3.

5.

3. The method for preparing a self-emulsifying full-spectrum compound microemulsion sunscreen agent according to claim 2, characterized in that: In step 1), the mass ratio of the oily solvent, ethylhexyl triazine ketone, diethylamino hydroxybenzoyl hexyl benzoate, and cresoltrazol trisiloxane is 16.5-19.5: 7.5-8.5: 5.5-6.5: 5.5-6.

5.

4. The method for preparing a self-emulsifying full-spectrum compound microemulsion sunscreen agent according to claim 1, characterized in that: In step 2), the mass ratio of aqueous solvent, humectant, and methylenebis-benzotriazolyltetramethylbutyrol is 36.3-19.3:7.05-9.15:3.5-4.

5. The aqueous solvent is deionized water, and the humectant is a compound of glycerin and sodium hyaluronate. In the humectant, the mass ratio of glycerin and sodium hyaluronate is 7-9:0.05-0.

15.

5. The method for preparing a self-emulsifying full-spectrum compound microemulsion sunscreen according to claim 1, characterized in that: In step 3), the mass ratio of the oil phase, polyglycerol-6 laurate, PEG-20 glycerol triisostearate, polyethylene glycol-30 dimer hydroxystearate, and hydrogenated lecithin is 35-41: 9.5-10.5：2-2.8：0.4-0.6：1.5-2.5。 6. The method for preparing a self-emulsifying full-spectrum compound microemulsion sunscreen agent according to claim 1, characterized in that: In step 4), the mass ratio of the pretreated oil phase to the aqueous phase is 48.4-57.4:32.95-46.

85.

7. The method for preparing a self-emulsifying full-spectrum compound microemulsion sunscreen agent according to claim 1, characterized in that: In step 5), the mass ratio of the mixed phase, gelatin, sodium alginate aqueous solution, and glutaraldehyde aqueous solution is 90.35-95.25: 2.5-3.5: 1.5-2.5: 0.5-1.

5. The concentration of the sodium alginate aqueous solution is 20 g / L; The mass concentration of the glutaraldehyde aqueous solution is 0.5%.

8. The method for preparing a self-emulsifying full-spectrum compound microemulsion sunscreen agent according to claim 1, characterized in that: In step 6), the mass ratio of the composite wall material microcapsule system to the preservative is 97.85-99.75:0.2-2. The preservative is a compound of p-hydroxyacetophenone and 1,2-hexanediol, and the mass ratio of p-hydroxyacetophenone and 1,2-hexanediol is 0.1-1:0.1-1.

9. A self-emulsifying, full-spectrum, compound microemulsion sunscreen agent, characterized in that: It is prepared by the method of preparing the self-emulsifying full-spectrum compound microemulsion capsule sunscreen as described in any one of claims 1-8.

10. The application of a self-emulsifying full-spectrum compound microemulsion sunscreen agent according to claim 9, characterized in that: The self-emulsifying full-spectrum compound microemulsion sunscreen agent is added to the sunscreen product formulation to prepare the sunscreen product, and the mass content of the self-emulsifying full-spectrum compound microemulsion sunscreen agent in the sunscreen product is 10-20%.

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