Method for detecting methyl benzoate in atomized liquid, electronic equipment and storage medium

Abstract

The invention belongs to the technical field of electronic atomization, and particularly relates to a method for detecting methyl benzoate in atomized liquid, electronic equipment and a storage medium. The method comprises the following steps: obtaining storage conditions and water activity of atomized liquid to be detected, wherein the components of the atomized liquid to be detected comprise neotame and benzoic acid; and determining the content of methyl benzoate generated by the esterification reaction of methanol and benzoic acid according to the storage condition and the water activity of the atomized liquid to be detected. According to the method, the neotame in the atomized liquid without methyl benzoate is subjected to kinetic research, and the potential methyl benzoate generation amount can be obtained based on the storage condition and the water activity of any atomized liquid, so that the risk of the atomized liquid is evaluated.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of electronic atomization, and particularly relates to a method for detecting methyl benzoate in atomized liquid, an electronic device and a storage medium. BACKGROUND

[0002] Since methyl benzoate can cause chronic respiratory diseases, it is particularly important to monitor methyl benzoate in atomized liquid. The current method for checking methyl benzoate is to check atomized liquid raw materials one by one. However, even if methyl benzoate is found, it cannot be traced back to whether it is brought by the raw material itself or generated in situ during the storage or use of the chemical substances in the raw material. In any case, this method is time-consuming and labor-intensive. SUMMARY

[0003] The application aims to provide a method for detecting methyl benzoate in atomized liquid, an electronic device and a storage medium, to solve the problem of time-consuming and labor-intensive method for checking methyl benzoate.

[0004] To solve the above technical problems, the application provides a method for detecting atomized liquid, which comprises: obtaining the storage condition and water activity of the atomized liquid to be detected, the components of the atomized liquid to be detected comprising neotame and benzoic acid; determining the content of methyl benzoate generated by esterification reaction of methanol and benzoic acid according to the storage condition and water activity of the atomized liquid to be detected.

[0005] In one embodiment, the storage condition of the atomized liquid to be detected comprises: storage temperature of the atomized liquid to be detected, storage time of the atomized liquid to be detected.

[0006] In one embodiment, the method for determining the content of methyl benzoate generated by esterification reaction of methanol and benzoic acid according to the storage condition and water activity of the atomized liquid to be detected comprises: inputting the storage temperature of the atomized liquid to be detected into a neotame hydrolysis reaction rate influence intensity constant formula to determine the neotame hydrolysis reaction rate influence intensity constant in the atomized liquid to be detected; obtaining the initial rate constant of neotame hydrolysis reaction in the atomized liquid to be detected according to the neotame hydrolysis reaction rate influence intensity constant in the atomized liquid to be detected and the water activity of the atomized liquid to be detected; obtaining the neotame content corresponding to the storage time according to the initial rate constant of neotame hydrolysis reaction in the atomized liquid to be detected and the storage time of the atomized liquid to be detected; and obtaining the content of methyl benzoate according to the neotame content corresponding to the storage time and the initial neotame content of the atomized liquid to be detected.

[0007] In one embodiment, the neotame hydrolysis reaction rate influence intensity constant formula is as follows: p = 1.306 x 10 17 exp (-15343 / T); wherein p is the neotame hydrolysis reaction rate influence intensity constant; and T is the storage temperature of the atomized liquid to be detected.

[0008] In one embodiment, the formula of the intensity constant of the neotame hydrolysis reaction rate is obtained by: configuring sample atomized liquids with different water activities; performing aging tests on the sample atomized liquids with different water activities at a target temperature to obtain a relationship between the preset rate constant of the neotame hydrolysis reaction and the water activity at the target temperature; obtaining the intensity constant of the neotame hydrolysis reaction at the target temperature according to the relationship between the preset rate constant of the neotame hydrolysis reaction and the water activity at the target temperature; performing aging tests at different target temperatures to obtain the intensity constant of the neotame hydrolysis reaction rate at different target temperatures; and obtaining a relationship between the intensity constant of the neotame hydrolysis reaction rate and the temperature according to the intensity constant of the neotame hydrolysis reaction rate at different target temperatures, and taking the relationship between the intensity constant of the neotame hydrolysis reaction rate and the temperature as the formula of the intensity constant of the neotame hydrolysis reaction rate.

[0009] In one embodiment, the aging tests on the sample atomized liquids with different water activities at a target temperature to obtain a relationship between the preset rate constant of the neotame hydrolysis reaction and the water activity at the target temperature include: performing aging tests on sample atomized liquids with a target water activity at the target temperature to obtain corresponding neotame concentrations at different sampling times; obtaining the preset rate constant of the neotame hydrolysis reaction at the target water activity according to the corresponding neotame concentrations at different sampling times and the initial neotame concentration; performing aging tests at different water activities to obtain the preset rate constant of the neotame hydrolysis reaction at different water activities; and obtaining the relationship between the preset rate constant of the neotame hydrolysis reaction and the water activity at the target temperature according to the preset rate constant of the neotame hydrolysis reaction at different water activities and the water activity.

[0010] In one embodiment, the initial rate constant of the neotame hydrolysis reaction in the to-be-tested atomized liquid is obtained according to the intensity constant of the neotame hydrolysis reaction rate in the to-be-tested atomized liquid and the water activity of the to-be-tested atomized liquid by the following formula: K1(T, aw) = p x aw; wherein K1(T, aw) is the initial rate constant of the neotame hydrolysis reaction; p is the intensity constant of the neotame hydrolysis reaction rate; and aw is the water activity of the atomized liquid.

[0011] In one embodiment, the methyl benzoate content is obtained according to the neotame content corresponding to the storage time, the initial neotame content of the to-be-tested atomized liquid, and the following formula: X = (C o -C t ) x 0.4; wherein X is the generation amount of methyl benzoate; C0 is the initial neotame concentration; C t is the neotame concentration at the time t of storage.

[0012] The application also provides an electronic device, which comprises a processor, a memory, and a program or instructions stored in the memory and executable on the processor, and the program or instructions are executed by the processor to implement the steps of the method described above.

[0013] The application further provides a computer readable storage medium, and a program or instructions are stored on the computer readable storage medium, and the program or instructions are executed by a processor to realize steps of the method.

[0014] The application provides a method for detecting methyl benzoate in atomized liquid, the method performs kinetic study on neotame in atomized liquid without methyl benzoate, and based on storage conditions and water activity of any atomized liquid, potential methyl benzoate generation amount can be obtained, so as to evaluate the risk of the atomized liquid, and the method saves time and labor.

[0015] Additional aspects and advantages of the application will be made apparent by the following description and the appended claims. BRIEF DESCRIPTION OF DRAWINGS

[0016] The above and / or additional aspects and advantages of the application will become apparent and be readily appreciated from the following description, including the accompanying drawings, wherein: Figure 1 is a flowchart of a method for detecting methyl benzoate in atomized liquid according to an embodiment of the application; Figure 2 is a diagram of an electronic device according to an embodiment of the application. DETAILED DESCRIPTION

[0017] Embodiments of the application will be described in detail below, examples of which are shown in the drawings, wherein the same or similar reference signs represent the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the drawings are exemplary and are only used to explain the application, and cannot be understood as a limitation on the application. Based on the embodiments in the application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the application.

[0018] The terms "first", "second" in the description and claims of the application can explicitly or implicitly include one or more features. In the description of the application, unless otherwise specified, the meaning of "a plurality of" is two or more. In addition, "and / or" in the specification and claims means at least one of the connected objects, and the character " / ", generally means that the front and rear associated objects are in an "or" relationship.

[0019] In the description of the present application, it is understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application.

[0020] In the description of the present application, it should be noted that unless otherwise explicitly specified and limited, the terms "mounting", "connection", "connection" should be understood broadly, for example, it can be fixed connection, or detachable connection, or integral connection; it can be mechanical connection, or electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, or it can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0021] All raw materials of the current atomized liquid do not contain methyl benzoate, but a small amount of methyl benzoate can still be detected. Analysis of this result found that methyl benzoate is generated by esterification of methanol produced by hydrolysis of sweetener neotame in the atomized liquid and benzoic acid in the atomized liquid under acidic conditions. The specific principle is as follows: the 3,3-dimethylbutyl group in the structure of neotame produces a large steric hindrance effect, making neotame relatively stable and difficult to hydrolyze, but in the acidic and high-temperature environment of the atomized liquid, the methyl ester group in neotame may be hydrolyzed to produce a small amount of methanol, which reacts with the high content of benzoic acid in the atomized liquid to produce methyl benzoate. Because the ester group in the structure of methyl benzoate forms a conjugated system (π-π conjugation) with the benzene ring, and in the high content of benzoic acid system in the atomized liquid, the formed methyl benzoate is stable and not easy to occur reverse hydrolysis reaction, therefore the methyl benzoate produced by the reaction is stably present in the atomized liquid.

[0022] The key parameter of the hydrolysis reaction of neotame in the atomized liquid system is water activity (water activity, abbreviated as aw). Water activity refers to the "energy state" or "availability" of water in the atomized liquid system, which can directly reflect the ability of water to participate in chemical reactions. At the same time, the higher the aw, the faster the hydrolysis reaction rate, therefore, the hydrolysis reaction of neotame can be understood as a reaction affected by temperature and water activity. Therefore, the present application designs a scheme for predicting the content of potential methyl benzoate based on the temperature and water activity content prediction model of the atomized liquid.

[0023] The application provides a detection method of atomized liquid, as shown in the following formula (I): Figure 1 The method comprises the following steps: S1, obtaining the storage condition and water activity of the atomized liquid to be detected; S2, determining the content of methyl benzoate generated by esterification reaction of methanol and benzoic acid according to the storage condition and water activity of the atomized liquid to be detected.

[0024] In an embodiment, the storage condition of the atomized liquid to be detected comprises the storage temperature of the atomized liquid to be detected and the storage time of the atomized liquid to be detected.

[0025] The method can quantitatively determine the potential generation amount of methyl benzoate in the atomized liquid without methyl benzoate, and can evaluate the risk of the atomized liquid based on the storage condition and water activity of the atomized liquid, and the method is time-saving and labor-saving.

[0026] In step S1, the storage temperature T and storage time t of the atomized liquid to be detected can be obtained, and the corresponding water activity aw can be measured by a water activity tester. Based on these parameters of the atomized liquid to be detected, the content of methyl benzoate can be accurately predicted.

[0027] Step S2 specifically comprises the following steps: S21, configuring sample atomized liquids with different water activities. The following is only an example for better understanding of the scheme.

[0028] For example, the components of the experimental group atomized liquid are as follows: 50% propylene glycol (PG), 2% nicotine benzoate, 1% cooling agent N, 2, 3-trimethyl-2-(1-methylethyl) butyramide (WS-23), 2000 mg / L neotame, and finally glycerol is added to 100%. The components of the blank control group atomized liquid are the same as those of the experimental group, and the difference is that the neotame is not added in the components.

[0029] The water activities aw of the above-mentioned blank control group and experimental group atomized liquids are adjusted to 0.2, 0.4, 0.6 and 0.8 by sodium chloride or potassium chloride, and are marked as 0, 1-1, 1-2, 2-1……4-2. After vortex mixing for 1 nin, defoaming is performed, and the atomized liquids are ready for use.

[0030] S22, performing an aging test on the sample atomized liquids with different water activities at a target temperature to obtain the relationship between the preset rate constant of neotame hydrolysis reaction and the water activity at the target temperature, comprising: The sample neotame solution of target water activity is aged at a target temperature to obtain the corresponding neotame concentration at different sampling times. For example, all the sample neotame solutions in S21 are placed in constant temperature ovens at 40°C, 60°C and 80°C, respectively. Samples are taken at 0, 24, 48, 96 and 168 hours, respectively, and the neotame concentration C is determined by HPLC. t The results are shown in Tables 1-3 below.

[0031] Table 1: Results of neotame detection concentration at each time point of 40°C accelerated aging experiment

[0032] The formula of the neotame hydrolysis reaction rate in the sample neotame solution is: k = In(C o / C t ) / t (1). wherein k is the neotame hydrolysis reaction rate constant (i.e., the preset rate constant) at temperature T, with the unit of h -1 ; C0 is the initial neotame concentration, with the unit of mg / L; C t is the neotame concentration at time t, with the unit of mg / L; and t is the accelerated aging time, with the unit of h.

[0033] According to the corresponding neotame concentration at different sampling times and the initial neotame concentration, the preset rate constant of the neotame hydrolysis reaction at the target water activity can be obtained. For example, according to the results of the above 40°C accelerated aging experiment, the neotame detection concentration at different activities aw and different sampling times t can be obtained. Therefore, at the same water activity aw, the linear is plotted with t as the horizontal coordinate and In(C o / C t ) as the vertical coordinate, and according to formula (1) k = In(C o / C t ) / t, it can be known that the slope of the plotted straight line is the neotame hydrolysis reaction rate constant k. Finally, the obtained data are: k = 0.000016 h -1 at aw = 0.2, k = 0.000029 h -1 at aw = 0.4, k = 0.000043 h -1 at aw = 0.6, and k = 0.000056 h -1 at aw = 0.8.

[0034] According to the preset rate constant of neotame hydrolysis reaction under different water activity and the water activity, the relationship between the preset rate constant of neotame hydrolysis reaction and the water activity under the target temperature is obtained, such as the last integration of neotame hydrolysis reaction rate constant k and aging time t under different water activity aw, such as taking water activity aw as the horizontal coordinate, neotame hydrolysis reaction rate constant k as the vertical coordinate to draw the linearity, k = 6.7 x 10 -5 aw+ 3 x 10 -6 , R 2 = 0.9997. It can be seen that under the same temperature T, the neotame hydrolysis reaction rate constant k has a linear relationship with the water activity aw, and the higher the water activity aw, the higher the neotame hydrolysis efficiency.

[0035] Table 2 Neotame detection concentration results of 60℃ accelerated aging experiment at each time point

[0036] Similarly, according to the above 60℃ accelerated aging experiment results, k = 0.000239h -1 under aw = 0.2, k = 0.000531h -1 under aw = 0.4, k = 0.000810h -1 under aw = 0.6, k = 0.001067h -1 under aw = 0.8. Finally, the neotame hydrolysis reaction rate constant k and the aging time t under different water activity aw are integrated, such as taking water activity aw as the horizontal coordinate, neotame hydrolysis reaction rate constant k as the vertical coordinate to draw the linearity, k = 0.001382aw- 0.000029, R 2 = 0.9991.

[0037] Table 3 Neotame detection concentration results of 80℃ accelerated aging experiment at each time point

[0038] Similarly, according to the above 80℃ accelerated aging experiment results, k = 0.004029h -1 under aw = 0.2, k = 0.007443h -1 under aw = 0.4, k = 0.011088h -1 under aw = 0.6, k = 0.014257h -1Finally, the hydrolysis reaction rate constant k of neotame at different water activity aw and aging time t were integrated, and a linear graph was drawn with water activity aw as the horizontal coordinate and the hydrolysis reaction rate constant k as the vertical coordinate, to obtain k=0.017165aw+0.000622, R 2 =0.9993.

[0039] S23、According to the relationship between the preset rate constant of neotame hydrolysis reaction at the target temperature and the water activity, the intensity constant of neotame hydrolysis reaction at the target temperature is obtained.

[0040] Based on the preset rate constant of neotame hydrolysis reaction under the coupling effect of temperature and water activity, the Arrhenius equation of neotame hydrolysis reaction is constructed: p=A×exp(Ea / RT) (2); The formula (2) is transformed to obtain: ln(p)=- (Ea / R) × (1 / T) + ln(A) (3); Wherein, p is the rate influencing intensity constant of neotame hydrolysis reaction, the unit is h -1 ; Ea is the activation energy of neotame hydrolysis reaction, the unit is J / mol; A is the pre-exponential factor, the unit is h -1 ; R is the ideal gas constant 8.314, the unit is J / (mol•K); T is the absolute temperature, T=℃+273.15, the unit is K.

[0041] According to the rate influencing intensity constant of neotame hydrolysis reaction at different target temperatures, the relationship between the rate influencing intensity constant of neotame hydrolysis reaction and temperature is obtained, and the relationship between the rate influencing intensity constant of neotame hydrolysis reaction and temperature is taken as the rate influencing intensity constant formula of neotame hydrolysis reaction. According to the step S22, it is known that at T=40℃, i.e. 313.15K, k=6.7×10 -5 aw+3×10 -6 ; at T=60℃, i.e. 333.15K, k=0.001382aw-0.000029; at T=80℃, i.e. 353.15K, k=0.017165aw+0.000622. A linear equation is established with 1 / T as the horizontal coordinate and ln(p) as the vertical coordinate, and linear regression fitting is performed to obtain the equation: ln(p)=-15343×(1 / T)+39.411. Wherein, the rate influencing intensity constant p of neotame hydrolysis reaction is the slope in the formula of the rate constant k of neotame hydrolysis reaction and water activity aw, such as at T=40℃, i.e. 313.15K, p is 6.7×10 -5 .

[0042] Comparing the equation ln(p)=-15343×(1 / T)+39.411 with the formula (3) ln(p)=-(Ea / R)×(1 / T)+ln(A), the slope -(Ea / R)=-15343, since R=8.314 J / (mol•K), so the reaction activation energy Ea=15343×8.314=127.56 KJ / mol; the intercept ln(A)=39.411, namely the pre-exponential factor A=exp(39.411)=1.306×10 17 Therefore, the Arrhenius equation (3) of the neotame hydrolysis reaction is p=1.306×10 17 ×exp(-15343 / T), namely the neotame hydrolysis reaction rate influence strength constant formula.

[0043] S24, the product of the neotame hydrolysis reaction rate influence strength constant p and the water activity aw is taken as the rate constant k1 (namely the initial rate constant) of the neotame hydrolysis reaction based on the coupling effect of temperature and water activity, the equation is K1(T, aw)=p×aw (4); Wherein, k1 is the rate constant of the neotame hydrolysis reaction based on the coupling effect of temperature and water activity; p is the neotame hydrolysis reaction rate influence strength constant, the unit is h -1 ; aw is the water activity, dimensionless.

[0044] S25, based on the storage temperature of any to-be-measured atomized liquid, the neotame hydrolysis reaction rate influence strength constant can be obtained according to the formula (3), and then combined with the water activity of the to-be-measured atomized liquid, the rate constant k1 of the neotame hydrolysis reaction based on the coupling effect of temperature and water activity can be obtained according to the formula (4). Then according to the formula (1) k=In(C o / C t ) / t and the storage time of the to-be-measured atomized liquid, the neotame concentration C t corresponding to the time can be obtained.

[0045] S26, the methyl benzoate content is obtained according to the neotame content corresponding to the storage time and the initial neotame content of the to-be-measured atomized liquid.

[0046] As can be deduced from the reaction equation of the neotame hydrolysis product methanol and benzoic acid to generate methyl benzoate, the relationship between the neotame consumption and the methyl benzoate generation is as follows: W=(C o -C t )×P1 (5); P1=(M2 / M1) (6); Substituting formula (6) into formula (5) to obtain: W=(C o -C t )×(M2 / M1) (7); Wherein, W is the methanol production of the neotame hydrolysis reaction, the unit is mg / L; C0 is the initial neotame concentration, the unit is mg / L; C t is the neotame concentration at t time, the unit is mg / L; M2 is the molecular weight of methanol, 32 g / mol; M1 is the molecular weight of neotame, 378.5 g / mol; P1 is the molar conversion coefficient of neotame hydrolysis reaction, dimensionless.

[0047] X=W×P2 (8); P2=(M3 / M2) (9); Substitute formula (9) into formula (8) to obtain: X=W×(M3 / M2) (10); Substitute formula (7) into formula (10) to obtain: X=(C 0- C t )×(M2 / M1)×(M3 / M2) (11); Wherein, X is the methyl benzoate production, the unit is mg / L; W is the methanol production of the neotame hydrolysis reaction, the unit is mg / L; M3 is the molecular weight of methyl benzoate, 136 g / mol; P2 is the molar conversion coefficient of esterification reaction, dimensionless.

[0048] Since M1, M2 and M3 are fixed values, formula (11) is obtained: X=(C o -C t )×0.4(12)。

[0049] S34, according to S33, the neotame concentration C t stored to this time is obtained, combined with formula (12) X=(C o -C t )×0.4, the methyl benzoate production represented by X can be obtained.

[0050] In order to better explain the scheme, the following also provides examples.

[0051] Example 1 The test aerosol liquid is acid blueberry raspberry flavor aerosol liquid, the neotame addition amount in the aerosol liquid is 1151 mg / g, the storage time is 3 days, the storage temperature is 38℃, and the water activity aw is 0.4223.

[0052] Example 2 The test aerosol liquid is triple mango flavor aerosol liquid, the neotame addition amount in the aerosol liquid is 1143 mg / g, the storage time is 3 days, the storage temperature is 38℃, and the water activity aw is 0.4119.

[0053] Example 3 The to-be-tested atomized liquid is an acid blueberry raspberry flavored atomized liquid, the neotame addition amount in the atomized liquid is 1151 mg / g, the storage time is 7 days, the storage temperature is 38℃, and the water activity aw is 0.4223.

[0054] Example 4 The to-be-tested atomized liquid is an acid blueberry raspberry flavored atomized liquid, the neotame addition amount in the atomized liquid is 1151 mg / g, the storage time is 3 days, the storage temperature is 50℃, and the water activity aw is 0.4223.

[0055] Example 5 The to-be-tested atomized liquid is an acid blueberry raspberry flavored atomized liquid, the neotame addition amount in the atomized liquid is 1151 mg / g, the storage time is 3 days, the storage temperature is 20℃, and the water activity aw is 0.4223.

[0056] Example 6 The to-be-tested atomized liquid is an acid blueberry raspberry flavored atomized liquid, the neotame addition amount in the atomized liquid is 1151 mg / g, the storage time is 3 days, the storage temperature is 38℃, and the water activity aw is 0.2.

[0057] Example 7 The to-be-tested atomized liquid is an acid blueberry raspberry flavored atomized liquid, the neotame addition amount in the atomized liquid is 1151 mg / g, the storage time is 3 days, the storage temperature is 38℃, and the water activity aw is 0.6.

[0058] The storage temperature of the to-be-tested atomized liquid in the example is input into the neotame hydrolysis reaction rate intensity constant formula p = 1.306 x 10 17 × exp (-15343 / T) to obtain the neotame hydrolysis reaction rate intensity constant. Then, according to the water activity, the initial rate constant of the neotame hydrolysis reaction based on the coupling effect of temperature and water activity is obtained through the formula K1(T, aw) = p x aw. Then, according to the storage time of the to-be-tested atomized liquid, the neotame concentration C o corresponding to the time is obtained through the formula k = In(C t / C t ) / t. Finally, the methyl benzoate content is obtained through the formula X = (C o -C t ) x 0.4 according to the neotame addition amount (initial concentration). In order to verify the feasibility of the scheme protected in the present application, the to-be-tested atomized liquid after storage for the corresponding time in the example was tested by GC-MS, and the test data are shown in Table 4.

[0059] Table 4 Calculation data and test data of the atomized liquid in the example

[0060] According to the data in Table 4, the relative deviation of the methyl benzoate concentration measured by the present scheme and the methyl benzoate concentration measured by GC-MS is less than 5%, which indicates the applicability and accuracy of the method. Meanwhile, the method has a faster detection speed, which solves the problem of time and labor consumption.

[0061] The present application also provides an electronic device, such as Figure 2 The processor 210, the memory 200, the communication interface 220, the input device 230, and the output device 240 in the electronic device are connected to each other through a bus. The memory 200 is configured to store instructions executable by the processor 210; and the processor 210 is configured to execute the method disclosed in any of the above embodiments by running the instructions in the memory 200.

[0062] The present application also provides a readable storage medium, and the readable storage medium stores a program or instructions, which are executed by a processor to implement various processes of the above method embodiments and achieve the same technical effects. To avoid repetition, details are not described here.

[0063] The processor is the processor in the electronic device in the above embodiments. The readable storage medium includes a computer readable storage medium, such as a computer readable memory (Read-Only Memory, ROM), a random access memory (Random Access Memory, RAM), a magnetic disk, or an optical disk.

[0064] It should be noted that, in this document, the terms "comprising", "including", or any other variant thereof are intended to cover non-exclusive inclusions, so that a process, method, article, or device that includes a list of elements does not only include those elements, but also includes other elements not explicitly listed, or further includes elements inherent in such a process, method, article, or device. Without more limitations, the element defined by the statement "including a" does not exclude the presence of additional identical elements in the process, method, article, or device including the element. In addition, it should be pointed out that the scope of the methods and devices in the present application is not limited to the order of performing the functions shown or discussed, but can also include performing the functions in a substantially simultaneous manner or in a reverse order, for example, the described method can be performed in an order different from that described, and various steps can be added, omitted, or combined. In addition, the features described with reference to certain examples can be combined in other examples.

[0065] Those skilled in the art can clearly understand the above-mentioned embodiment method can be realized by means of software and the necessary general hardware platform, of course, also can be through hardware, but many cases the former is the better embodiment. Based on such understanding, the technical solutions of the present application essentially or say the part of the contribution to the prior art can be embodied in the form of software products, the computer software product is stored in a storage medium (such as ROM / RAM, magnetic disk, optical disc), including a number of instructions to make a terminal (may be a mobile phone, computer, server, air conditioner, or network equipment, etc.) executes the method described in various embodiments of the present application.

[0066] The embodiments of the present application are described above in conjunction with the drawings, but the present application is not limited to the above-mentioned specific embodiments, the above-mentioned specific embodiments are only illustrative, but not limited, those skilled in the art can make many forms without departing from the purpose of the present application and the scope of the claims under the inspiration of the present application, all belong to the protection of the present application.

Claims

1. A method for detecting atomizing fluid, characterized in that, The method includes: The storage conditions and water activity of the atomizing liquid to be tested are obtained, wherein the components of the atomizing liquid to be tested include neotame and benzoic acid; The content of methyl benzoate generated by the esterification reaction of methanol and benzoic acid was determined based on the storage conditions and water activity of the atomizing liquid to be tested.

2. The method according to claim 1, characterized in that, The storage conditions of the atomizing liquid to be tested include: the storage temperature of the atomizing liquid to be tested and the storage time of the atomizing liquid to be tested.

3. The method according to claim 2, characterized in that, Based on the storage conditions and water activity of the atomizing solution to be tested, the content of methyl benzoate generated by the esterification reaction of methanol and benzoic acid is determined, including: The storage temperature of the atomized liquid to be tested is input into the formula for the influence constant of the neotame hydrolysis reaction rate, and the influence constant of the neotame hydrolysis reaction rate in the atomized liquid to be tested is determined. The initial rate constant of the neotame hydrolysis reaction in the test atomized liquid is obtained based on the influence constant of the neotame hydrolysis reaction rate in the test atomized liquid and the water activity of the test atomized liquid. The neotame content corresponding to the storage time is obtained based on the initial rate constant of the neotame hydrolysis reaction in the test atomized liquid and the storage time of the test atomized liquid. The methyl benzoate content was obtained based on the neotame content corresponding to the storage time and the initial neotame content of the atomizing liquid to be tested.

4. The method according to claim 3, characterized in that, The formula for the strength constant affecting the rate of neotame hydrolysis is as follows: p=1.306×10 17 ×exp(-15343 / T); Where p is the intensity constant of the effect of neotame hydrolysis reaction rate; T is the storage temperature of the atomized liquid to be tested.

5. The method according to claim 4, characterized in that, The formula for the strength constant of the effect of the neotame hydrolysis reaction rate is obtained by: Prepare sample nebulizers with different water activities; The sample atomized liquids with different water activities were subjected to aging tests at the target temperature to obtain the relationship between the preset rate constant of the neotame hydrolysis reaction and the water activity at the target temperature. Based on the relationship between the preset rate constant of the neotame hydrolysis reaction and the water activity at the target temperature, the intensity constant of the neotame hydrolysis reaction at the target temperature is obtained. Aging tests were conducted at different target temperatures to obtain the intensity constant of the effect of neotame hydrolysis reaction rate at different target temperatures. Based on the influence constant of the neotame hydrolysis reaction rate at different target temperatures, the relationship between the influence constant of the neotame hydrolysis reaction rate and temperature is obtained, and the relationship between the influence constant of the neotame hydrolysis reaction rate and temperature is used as the formula for the influence constant of the neotame hydrolysis reaction rate.

6. The method according to claim 5, characterized in that, The sample atomized liquids with different water activities were subjected to aging tests at the target temperature to obtain the relationship between the preset rate constant of the neotame hydrolysis reaction and the water activity at the target temperature, including: At the target temperature, an aging test was conducted on the sample atomized liquid with the target water activity to obtain the neotame concentration corresponding to different sampling times; Based on the neotame concentration and initial neotame concentration at different sampling times, the preset rate constant of neotame hydrolysis reaction at the target water activity was obtained. Aging tests were conducted with different water activities to obtain the preset rate constant for the hydrolysis reaction of neotame under different water activities; Based on the preset rate constant and water activity of the neotame hydrolysis reaction at different water activities, the relationship between the preset rate constant and water activity of the neotame hydrolysis reaction at the target temperature was obtained.

7. The method according to claim 3, characterized in that, Based on the influence constant of the neotame hydrolysis reaction rate in the test atomized liquid and the water activity of the test atomized liquid, the initial rate constant of the neotame hydrolysis reaction in the test atomized liquid is obtained by the following formula: K1(T,aw) = p × aw; Where K1(T,aw) is the initial rate constant of the neotame hydrolysis reaction; p is the intensity constant of the influence of the neotame hydrolysis reaction rate; and aw is the water activity of the atomizing liquid.

8. The method according to claim 3, characterized in that, Based on the neotame content corresponding to the storage time and the initial neotame content of the atomizing solution to be tested, the methyl benzoate content is obtained using the following formula: X=(C o -C t )×0.4; Where X is the amount of methyl benzoate produced; C0 is the initial neotame concentration; C t The concentration of neotame at storage time t.

9. An electronic device, characterized in that, It includes a processor, a memory, and a program or instructions stored in the memory and executable on the processor, wherein the program or instructions, when executed by the processor, implement the steps of the method as described in any one of claims 1 to 8.

10. A computer-readable storage medium, characterized in that, The readable storage medium stores a program or instructions that, when executed by a processor, implement the steps of the method as described in any one of claims 1 to 8.

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