Pesticide insecticidal composition as well as preparation method and application thereof

Abstract

The invention relates to a pesticide insecticidal composition and a preparation method and application thereof, and relates to the field of pesticides, the effective components comprise chlorantraniliprole and sanguinarine sulfate, and the weight ratio of chlorantraniliprole to sanguinarine sulfate is 99: 1-1: 99. According to the invention, chlorantraniliprole and sanguinarine sulfate are compounded together, so that pests can be killed to the greatest extent, and meanwhile, crops are stimulated to repair damage, so that the purposes of repairing after pests and rejuvenating are achieved. Subsequent growth of crops is guaranteed, and social value and economic value of stabilizing and increasing yield and improving quality are achieved.

Description

Technical Field

[0001] This invention relates to the field of pesticides, and in particular to a pesticide insecticidal composition, its preparation method, and its application. Background Technology

[0002] The information disclosed in this background section is intended only to enhance the understanding of the overall background of the invention and should not be construed as an admission or in any way implying that the information constitutes prior art known to those skilled in the art.

[0003] In recent years, climate change has intensified in my country, leading to more severe crop diseases and pests, and making crop growth more susceptible to climate influences. However, given China's large population, the demand for food crops and the requirements for their safety are even higher. Therefore, ensuring crop yield and quality has become a hot topic in contemporary research.

[0004] Although the use of pesticides is indispensable in agricultural production, the negative effects of excessive and frequent application of pesticides on crops, soil, and even the entire ecological environment cannot be ignored. At the same time, it leads to the continuous enhancement of pesticide resistance in pests, making the damage to crops more serious and control more difficult, thus creating a vicious cycle.

[0005] Reduced application and increased yield technology is an effective solution for pest and disease control and yield improvement. It meets the needs of crop growth and plays a huge role in promoting the sustainable development of modern agriculture, while also having broad development prospects.

[0006] Chlorantraniliprole, with the molecular formula C0.05 18 H 14 BrC l2 N5O2, relative molecular weight 483.2, CAS number: 500008-45-7, structural formula as shown in formula (1).

[0007] .

[0008] Chlorantraniliprole possesses a novel insecticidal mechanism through its chemical structure, effectively activating ryanodine (muscle) receptors in insects. This leads to the excessive release of calcium ions from intracellular calcium stores, causing paralysis and death in insects. It exhibits high activity against lepidopteran larvae, a broad insecticidal spectrum, and good persistence. Furthermore, chlorantraniliprole can disrupt the mating process of lepidopteran insects, reducing the oviposition rate of various noctuid moths. Therefore, it offers a longer and more stable effect than most insecticides.

[0009] Sanguinarinine sulfate is an extract of the poppy plant *Gnaphalium affine*, and one of the main active components of the total alkaloids in *Gnaphalium affine*, exhibiting good insecticidal activity. The English name for sanguinarinine sulfate is Sanguinarinum sulfate, and its molecular formula is C2.40 H 28 N2O 12 S, relative molecular weight 760.4, CAS number: 5578-73-4, structural formula as shown in formula (2): .

[0010] Studies have found that sanguinarine sulfate has some control efficacy against cabbage caterpillars, bean aphids, apple aphids, two-spotted spider mites, and pear psyllids on cruciferous vegetables. The recommended dosage for controlling cabbage caterpillars and bean aphids is 30-50 grams of 1% wettable powder per 667 square meters. Spraying during the early larval stages of cabbage caterpillars yields the best control effect and is safe for crops. Currently, there are no reports on the combination and application of chlorantraniliprole and sanguinarine sulfate. Summary of the Invention

[0011] Purpose of the invention The purpose of this invention is to provide a pesticide insecticidal composition, its preparation method, and its application. Through numerous experiments, this invention unexpectedly discovered that combining chlorantraniliprole and sanguinarine sulfate can maximize the killing of pests while simultaneously stimulating crop damage repair, achieving post-insect infestation recovery and revitalization. This ensures the subsequent growth of crops, resulting in stable yields, increased production, and improved quality—a significant social and economic benefit.

[0012] Solution To achieve the objective of this invention, this embodiment provides a pesticide insecticidal composition, the active ingredients of which include chlorantraniliprole and sanguinarine sulfate, wherein the weight ratio of chlorantraniliprole to sanguinarine sulfate is 99:1 to 1:99.

[0013] Further, the weight ratio of chlorantraniliprole to sanguinarine sulfate is 20:1 to 1:20, optionally 10:1 to 1:10, optionally 5:1 to 1:5, optionally 5:1 to 1:3, optionally 3:1 to 1:3, optionally 20:1, 15:1, 10:1, 5:1, 3:1, 1:3, 1:5, 1:10, 1:15 or 1:20.

[0014] Further, the active ingredient accounts for 1% to 90% of the total weight of the pesticide composition, optionally 16% to 50%.

[0015] Furthermore, it also includes additives selected from one or more of the following: synergists, dispersants, wetting agents, binders, disintegrants, emulsifiers, stabilizers, antifreeze agents, defoamers, preservatives, thickeners, solvents, and dispersion media.

[0016] Furthermore, the dosage form of the composition is at least one selected from the following: suspension concentrate, emulsifiable concentrate, microcapsule suspension concentrate, wettable powder, water-dispersible granules, microemulsion, and granules; preferably, it is a suspension concentrate.

[0017] Further, it includes the following raw materials in parts by weight: 1-50 parts chlorantraniliprole, 1-50 parts sanguisorbine sulfate, 1-10 parts dispersant, 0-10 parts wetting agent, 0.1-5 parts thickener, 0-10 parts antifreeze agent, and 49-69 parts water; Further, it includes the following raw materials in parts by weight: 1-40 parts chlorantraniliprole, 1-40 parts sanguisorbine sulfate, 4-10 parts dispersant, 0-10 parts wetting agent, 0.5-5 parts thickener, 0-10 parts antifreeze agent, and 49-69 parts water.

[0018] Furthermore, water was replenished to a total of 100 portions.

[0019] Furthermore, the dispersant includes one or more of sodium methylnaphthalene sulfonate formaldehyde condensate, sodium alkylnaphthalene sulfonate, sodium alkylnaphthalene sulfonate, and sodium lignin sulfonate.

[0020] Furthermore, thickeners include xanthan gum.

[0021] Furthermore, the wetting agent includes one or more of sodium butylnaphthalene sulfonate, sodium dodecyl sulfate, sodium butylnaphthalene sulfonate, and sodium dodecyl sulfate.

[0022] Furthermore, antifreeze agents include one or more of glycerol and ethylene glycol.

[0023] Secondly, a method for preparing the aforementioned pesticide insecticidal composition is provided, wherein the active ingredient and adjuvant are mixed in proportion, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain chlorantraniliprole·sanguisorbine sulfate suspension.

[0024] The raw materials include the following parts by weight: chlorantraniliprole 1-50 parts, sanguisorbine sulfate 1-50 parts, dispersant 1-10 parts, wetting agent 0-10 parts, thickener 0.1-5 parts, antifreeze agent 0-10 parts, and water 49-69 parts; Optionally, the raw materials include the following parts by weight: 1-40 parts of chlorantraniliprole, 1-40 parts of sanguisorbine sulfate, 4-10 parts of dispersant, 0-10 parts of wetting agent, 0.5-5 parts of thickener, 0-10 parts of antifreeze agent, and 49-69 parts of water; Optionally, water can be replenished to 100 servings.

[0025] Thirdly, the invention provides the application of the pesticide insecticidal composition described above or the pesticide insecticidal composition prepared by the method described above in the control of pests and / or the improvement of crop yield.

[0026] Furthermore, the pests include lepidopteran pests, and optionally the lepidopteran pests are at least one of the following: rice stem borer, rice leaf roller, corn borer, armyworm, codling moth, beet armyworm, diamondback moth, and bollworm.

[0027] Fourthly, a method of using the pesticide insecticidal composition described in the first aspect or the pesticide insecticidal composition prepared by the preparation method described in the second aspect is provided, wherein the pesticide composition is applied to the pest to be controlled or its growth medium at an effective dose, and optionally the effective ingredient is applied at a dose of 10-15 g / mu.

[0028] In order to facilitate the storage, transportation and use of the pesticide composition, the pesticide composition may also contain adjuvants.

[0029] The content of the adjuvant is not particularly required and can be the same as that of adjuvants used in the conventional preparation of suspension pesticides. Preferably, based on the total weight of the pesticide composition, the total content of chlorantraniliprole and sanguinarine sulfate is 1-90%, and the adjuvants and water are added to make up to 100% of the total weight of the pesticide suspension.

[0030] Beneficial effects (1) Compared with single agents, the pesticide composition of the present invention has a significant synergistic effect on lepidopteran pests, which improves the control effect.

[0031] (2) Compared with single agents, the pesticide composition of the present invention can reduce the amount of pesticide used in the field, effectively reducing environmental pollution and pesticide residues.

[0032] (3) The active ingredients in the pesticide composition of the present invention have different mechanisms of action, which helps to avoid and delay the development of pesticide resistance in pests.

[0033] (4) The chlorantraniliprole of the present invention has a significant effect on increasing crop yield. Sanguisorbine sulfate is extracted from plants and is a natural plant-derived component. The present invention selects chlorantraniliprole and sanguisorbine sulfate in combination to improve the insecticidal effect while promoting crop growth and increasing yield, thereby achieving the effect of reducing application and increasing yield. Detailed Implementation

[0034] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention. Unless otherwise expressly stated, throughout the specification and claims, the term "comprising" or its variations such as "including" or "comprising of," etc., will be understood to include the stated elements or components, and does not exclude other elements or other components.

[0035] Furthermore, to better illustrate the present invention, numerous specific details are provided in the following detailed embodiments. Those skilled in the art should understand that the present invention can be practiced without certain specific details. In some embodiments, materials, elements, methods, and means well known to those skilled in the art are not described in detail in order to highlight the spirit of the invention.

[0036] In the following examples, chlorantraniliprole and sanguinarine sulfate are technical grade products, both of which can be obtained commercially. Other raw materials are conventional commercially available products.

[0037] Test Example 1: Indoor toxicity determination of the combination of chlorantraniliprole and sanguinarine sulfate on rice stem borer. Experimental Methods: The experiment followed the principles of "Pesticide Bioassay Technology" (edited by Chen Nianchun, published by Beijing Agricultural University Press) and "Guidelines for Indoor Bioassay of Pesticides NY / T 1154.6-2006," employing the indoor immersion method for rice stem borer. Rice stem borers were immersed in the pesticide solution for 5-10 seconds, and excess solution was absorbed with filter paper before transferring them to normal rearing conditions. Each treatment was replicated four times, with 10-20 insects immersed in each replicate. A single pesticide treatment was included as a control. Mortality was assessed 24 hours after treatment, following the People's Republic of China National Standard GB / T17980.1-2000 "Guidelines for Field Efficacy Testing of Pesticides (I) Insecticides for Control of Lepidoptera Boring Pests of Rice." The control effect was calculated based on the rice stem borer mortality rate. Statistical analysis was performed using DPS data processing software to calculate the LC50 of each pesticide. 50 Then, the cotoxicity coefficient (CTC) is calculated according to Sun Yunpei's method.

[0038] Actual Toxicity Index (ATI) = (LC50 of Standard Reagent) 50 / LC of the test reagent 50 )×100.

[0039] Theoretical Toxicity Index (TTI) = Toxicity Index of Agent A × Percentage of A in the Mixture + Toxicity Index of Agent B × Percentage of B in the Mixture

[0040] Co-toxicity coefficient (CTC) = [Actual toxicity index (ATI) of mixture / Theoretical toxicity index (TTI) of mixture] × 100.

[0041] When CTC ≤ 80, the composition exhibits an antagonistic effect; when 80 < CTC < 120, the composition exhibits an additive effect; and when CTC ≥ 120, the composition exhibits a synergistic effect.

[0042] The results are shown in Table 1.

[0043] Table 1. Results of indoor toxicity tests of chlorantraniliprole and sanguinarine sulfate combination on rice stem borer.

[0044] The results in Table 1 show that chlorantraniliprole and sanguinarine sulfate have a synergistic effect on rice stem borer when the ratio is 20:1 to 1:20. Especially when the ratio is between 5:1 and 1:3, the co-toxicity coefficient of the listed ratios is higher than 160, and the synergistic effect is obvious.

[0045] Test Example 2: Indoor toxicity determination of the combination of chlorantraniliprole and sanguinarine sulfate on corn borer. Experimental Methods: The experiment followed the principles of "Pesticide Bioassay Technology" (edited by Chen Nianchun, published by Beijing Agricultural University Press) and "Guidelines for Indoor Bioassay of Pesticides NY / T 1154.6-2006," employing the indoor immersion method for corn borers. Corn borers were immersed in the pesticide solution for 5-10 seconds, excess solution was absorbed with filter paper, and the borers were then transferred to normal rearing conditions. Each treatment was repeated four times, with 10-20 borers immersed in each replicate. A single pesticide treatment was included as a control. Mortality was assessed 24 hours after treatment. The People's Republic of China National Standard GB / T 17980.6-2000 "Guidelines for Field Efficacy Testing of Pesticides (I) Insecticides for the Control of Corn Borers" was applied. The control effect was calculated based on the corn borer mortality rate. Statistical analysis was performed using DPS data processing software to calculate the LC50 of each pesticide. 50 Then, the cotoxicity coefficient (CTC) was calculated according to Sun Yunpei's method, and the results are shown in Table 2.

[0046] Table 2. Results of indoor toxicity tests of the combination of chlorantraniliprole and sanguinarine sulfate on corn borer.

[0047] Table 2 shows that chlorantraniliprole and sanguinarine sulfate have a synergistic effect on corn borers when the ratio is 20:1-1:20. Especially when the ratio is between 10:1-1:10, the co-toxicity coefficient of the listed ratios is higher than 160, and the synergistic effect is obvious.

[0048] Test Example 3: Indoor toxicity determination of chlorantraniliprole combined with sanguinarine sulfate against peanut bollworm. Experimental Methods: The experiment followed the principles of "Pesticide Bioassay Technology" (edited by Chen Nianchun, published by Beijing Agricultural University Press) and "Guidelines for Indoor Bioassay of Pesticides NY / T 1154.6-2006," employing the indoor immersion method for bollworm assay. Bollworms were immersed in the pesticide solution for 5-10 seconds, excess solution was absorbed with filter paper, and the bollworms were transferred to normal rearing conditions. Each treatment was repeated four times, with 10-20 bollworms immersed in each replicate. A single pesticide treatment was included as a control. Bollworm mortality was assessed 24 hours after treatment. The control effect was calculated using the mortality rate of bollworms, following the People's Republic of China National Standard GB / T 17980.5-2000 "Guidelines for Field Efficacy Testing of Pesticides (I) Insecticides for the Control of Bollworms." Statistical analysis was performed using DPS data processing software to calculate the LC50 of each pesticide. The co-toxicity coefficient (CTC) was then calculated using the Sun Yunpei method. The results are shown in Table 3.

[0049] Table 3. Results of indoor toxicity assays of the combined chlorantraniliprole and sanguinarine sulfate on cotton bollworm.

[0050] The results in Table 3 show that chlorantraniliprole and sanguinarine sulfate have a synergistic effect on cotton bollworm when the ratio is 20:1 to 1:20. Especially when the ratio is between 5:1 and 1:5, the co-toxicity coefficient of the listed ratios is higher than 160, and the synergistic effect is more obvious.

[0051] The pesticide composition of this invention can be prepared into a suspension suitable for agricultural use using known methods. Specific examples are provided below. In this application, the active ingredient or effective ingredient refers to chlorantraniliprole and sanguinarine sulfate. All percentages in the formulation are by mass percentages, and will not be repeated below.

[0052] Example 1: 21% chlorantraniliprole·sancalcein sulfate suspension (20:1) Chlorantraniliprole 20% Sanguisorbine sulfate 1% Sodium methylnaphthalenesulfonate formaldehyde condensate (dispersant) 5% Xanthan gum (thickener) 0.5% Sodium butylnaphthalenesulfonate (wetting agent) 3% Glycerol (antifreeze) 2% Add deionized water to bring the total to 100%.

[0053] The active ingredients, various additives, and solutions are thoroughly mixed according to the formula ratio, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain 21% chlorantraniliprole·sanguinarine sulfate suspension.

[0054] This example was applied to the beet armyworm. A 1500-fold dilution of 21% chlorantraniliprole·sanguisorbine sulfate suspension (effective concentration of chlorantraniliprole: 133.3 μg / ml; effective concentration of sanguisorbine sulfate: 6.67 μg / ml) was sprayed. The control efficacy at 7 and 15 days post-application was 81.5% and 92.9%, respectively. A 1000-fold dilution of 20% chlorantraniliprole suspension (effective concentration: 200 μg / ml) and a 1000-fold dilution of 40% sanguisorbine sulfate wettable powder were applied using the same method. The control efficacy at 7 days post-application was 70.6% and 41.3%, respectively, and at 15 days post-application, it was 84.3% and 32.1%, respectively. Further evidence shows that the combination of chlorantraniliprole and sanguinarine sulfate has a significant synergistic effect, and its control effect on beet armyworm is significantly better than that of single agents. Not only is the control effect improved, but the amount of active ingredient used is also significantly reduced compared to the use of single agents, which also reduces environmental pollution.

[0055] Example 2: 32% chlorantraniliprole·sancalcein sulfate suspension (15:1) Chlorantraniliprole 30% Sanguisorbine sulfate 2% Sodium methylnaphthalenesulfonate formaldehyde condensate (dispersant) 10% Xanthan gum (thickener) 1% 5% Ethylene glycol (antifreeze) Add deionized water to bring the total to 100%.

[0056] The active ingredients, various additives, and solutions are thoroughly mixed according to the formula ratio, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain 32% chlorantraniliprole·sanguinarine sulfate suspension.

[0057] This example was applied to the control of corn borers. A 32% chlorantraniliprole·sanguisorbine sulfate suspension was diluted with water at a ratio of 1500 (effective concentration of chlorantraniliprole: 200 μg / ml; effective concentration of sanguisorbine sulfate: 13.33 μg / ml) and sprayed. The control efficacy at 7 days and 15 days after application was 87.1% and 94.8%, respectively. A 20% chlorantraniliprole suspension diluted 1000 times (effective concentration: 200 μg / ml) and a 40% sanguisorbine sulfate wettable powder diluted 1000 times (effective concentration: 400 μg / ml), applied using the same method, showed control efficacies of 72.4% and 47.3% at 7 days after application, and 83.2% and 35.5% at 15 days after application, respectively. Further evidence shows that the combination of chlorantraniliprole and sanguinarine sulfate has a significant synergistic effect, and its control effect on corn borers is significantly better than that of single agents. Not only is the control effect improved, but the amount of active ingredient used is also significantly reduced compared to the use of single agents, which also reduces environmental pollution.

[0058] Example 3: 24% chlorantraniliprole·sancalcein sulfate suspension (5:1) Chlorantraniliprole 20% Sanguisorbine sulfate 4% Sodium alkylnaphthalene sulfonate (dispersant) 4% Xanthan gum (thickener) 1% 5% Ethylene glycol (antifreeze) Sodium dodecyl sulfate (wetting agent) 5% Add deionized water to bring the total to 100%.

[0059] The active ingredients, various additives, and solutions are thoroughly mixed according to the formula ratio, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain 24% chlorantraniliprole·sanguisorbine sulfate suspension.

[0060] This example was applied to the control of diamondback moth. A 24% chlorantraniliprole·sanguisorbine sulfate suspension was diluted 2000 times (effective concentration of chlorantraniliprole: 100 μg / ml; effective concentration of sanguisorbine sulfate: 20 μg / ml) with water and sprayed. The control efficacy at 7 days and 15 days after application was 85.2% and 90.5%, respectively. A 20% chlorantraniliprole suspension (Zhejiang Xin'an Chemical Group Co., Ltd.) diluted 2000 times (effective concentration: 100 μg / ml) and a 40% sanguisorbine sulfate wettable powder (Shaanxi Xianong Biotechnology Co., Ltd.) diluted 1000 times (effective concentration: 400 μg / ml) were applied using the same method. The control efficacy at 7 days after application was 71.2% and 35.2%, respectively, and at 15 days after application, it was 82.2% and 32.1%, respectively. Further evidence shows that the combination of chlorantraniliprole and sanguinarine sulfate has a significant synergistic effect, and its control efficacy against diamondback moth is significantly better than that of a single agent. Not only is the control effect improved, but the amount of active ingredient used is also significantly reduced compared to the use of either agent, thus also reducing environmental pollution.

[0061] Example 4: 50% chlorantraniliprole·sancalcein sulfate suspension (4:1) Chlorantraniliprole 40% Sanguisorbine sulfate 10% Sodium alkylnaphthalene sulfonate (dispersant) 4% Xanthan gum (thickener) 2% Sodium butylnaphthalenesulfonate (wetting agent) 3% Glycerol (antifreeze) 2% Add deionized water to bring the total to 100%.

[0062] The active ingredients, various additives, and solutions are thoroughly mixed according to the formula ratio, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain 50% chlorantraniliprole·sanguisorbine sulfate suspension.

[0063] This example was applied to the control of fruit tree fruit borer. A 2500-fold dilution of 50% chlorantraniliprole·sanguisorbine sulfate suspension (effective concentration of chlorantraniliprole: 160 μg / ml; effective concentration of sanguisorbine sulfate: 40 μg / ml) was sprayed. The control efficacy at 7 and 15 days post-application was 92.3% and 96.5%, respectively. A 1000-fold dilution of 20% chlorantraniliprole suspension (effective concentration: 200 μg / ml) and a 1000-fold dilution of 40% sanguisorbine sulfate wettable powder (effective concentration: 400 μg / ml) were applied using the same method. The control efficacies at 7 days post-application were 72.5% and 49.6%, respectively, and at 15 days post-application were 80.2% and 56.3%, respectively. Further evidence shows that the combination of chlorantraniliprole and sanguinarine sulfate has a significant synergistic effect, and its control effect on fruit tree fruit borer is significantly better than that of a single agent. Not only is the control effect improved, but the amount of active ingredient used is also significantly reduced compared to the use of either agent, thus reducing environmental pollution.

[0064] Example 5: 50% chlorantraniliprole·sancalcein sulfate suspension (1:4) 10% chlorantraniliprole Sanguisorbine sulfate 40% Sodium dodecyl sulfate (wetting agent) 2% Sodium lignosulfonate (dispersant) 5% Xanthan gum (thickener) 3% Add deionized water to bring the total to 100%.

[0065] The active ingredients, various additives, and solutions are thoroughly mixed according to the formula ratio, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain 50% chlorantraniliprole·sanguisorbine sulfate suspension.

[0066] This example was applied to control the rice stem borer, spraying the seedling trays before transplanting. A 1000-fold dilution of 50% chlorantraniliprole·sanguisorbine sulfate suspension (effective concentration of chlorantraniliprole: 100 μg / ml; effective concentration of sanguisorbine sulfate: 400 μg / ml) was used for spraying. The control efficacy was 88.9% and 95.2% at 10 and 20 days after application, respectively. A 2000-fold dilution of 20% chlorantraniliprole suspension (effective concentration: 100 μg / ml) and a 1000-fold dilution of 40% sanguisorbine sulfate wettable powder were applied using the same method. The control efficacies were 82.5% and 62.3% at 10 days, and 87.8% and 60.6% at 20 days, respectively. Further evidence shows that the combination of chlorantraniliprole and sanguinarine sulfate has a significant synergistic effect, and its control effect on rice stem borer is significantly better than that of a single agent. Not only is the control effect improved, but the amount of active ingredient used is also significantly reduced compared to using it alone, which also reduces environmental pollution.

[0067] Example 6: 30% chlorantraniliprole·sancalcein sulfate suspension (1:5) chlorantraniliprole 5% Sanguisorbine sulfate 25% Sodium methylnaphthalenesulfonate formaldehyde condensate (dispersant) 10% Xanthan gum (thickener) 1% Ethylene glycol (antifreeze) 4% Add deionized water to bring the total to 100%.

[0068] The active ingredients, various additives, and solutions are thoroughly mixed according to the formula ratio, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain 30% chlorantraniliprole·sanguinarine sulfate suspension.

[0069] This example was applied to control the rice stem borer, spraying the seedling trays before transplanting. A 30% chlorantraniliprole·sanguisorbine sulfate suspension was diluted 300 times (effective concentration of chlorantraniliprole: 166.7 μg / ml; effective concentration of sanguisorbine sulfate: 833.3 μg / ml) and sprayed. The control efficacy at 7 and 15 days after application was 89.1% and 96.3%, respectively. A 20% chlorantraniliprole suspension diluted 1000 times (effective concentration: 200 μg / ml) and a 40% sanguisorbine sulfate wettable powder diluted 1000 times (effective concentration: 400 μg / ml) were applied using the same method. The control efficacy at 7 days after application was 82.8% and 51.3%, respectively, and at 15 days after application, it was 90.1% and 52.8%, respectively. Further evidence shows that the combination of chlorantraniliprole and sanguinarine sulfate has a significant synergistic effect, and its control effect on rice stem borer is significantly better than that of a single agent. Not only is the control effect improved, but the amount of active ingredient used is also significantly reduced compared to using it alone, which also reduces environmental pollution.

[0070] Example 7: 20% chlorantraniliprole·sancalcein sulfate suspension (1:3) chlorantraniliprole 5% Sanguisorbine sulfate 15% Sodium methylnaphthalenesulfonate formaldehyde condensate (dispersant) 10% Xanthan gum (thickener) 1% Glycerol (antifreeze) 1% Add deionized water to bring the total to 100%.

[0071] The active ingredients, various additives, and solutions are thoroughly mixed according to the formula ratio, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain 30% chlorantraniliprole·sanguinarine sulfate suspension.

[0072] This example was applied to the control of corn armyworm. A 300-fold dilution of 20% chlorantraniliprole·sanguisorbine sulfate suspension (effective concentration of chlorantraniliprole: 166.7 μg / ml; effective concentration of sanguisorbine sulfate: 500.1 μg / ml) was sprayed. The control efficacy at 7 and 15 days after application was 90.3% and 93.2%, respectively. A 1000-fold dilution of 20% chlorantraniliprole suspension (effective concentration: 200 μg / ml) and a 1000-fold dilution of 40% sanguisorbine sulfate wettable powder (effective concentration: 400 μg / ml) were applied using the same method. The control efficacy at 7 days after application was 78.7% and 47.6%, respectively, and at 15 days after application, it was 85.3% and 52.5%, respectively. Further evidence shows that the combination of chlorantraniliprole and sanguinarine sulfate has a significant synergistic effect, and its control effect on corn armyworm is significantly better than that of single agents. Not only is the control effect improved, but the amount of active ingredient used is also significantly reduced compared to using them alone, which also reduces environmental pollution.

[0073] Example 8: 16% chlorantraniliprole·sancalcein sulfate suspension (1:15) 1% chlorantraniliprole Sanguisorbine sulfate 15% Sodium alkylnaphthalene sulfonate (dispersant) 4% Sodium lignosulfonate (dispersant) 2% Sodium dodecyl sulfate (wetting agent) 5% Add deionized water to bring the total to 100%.

[0074] The active ingredients, various additives, and solutions are thoroughly mixed according to the formula ratio, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain 16% chlorantraniliprole·sanguinarine sulfate suspension.

[0075] This example was applied to the control of rice leaf roller. A 500-fold dilution of 16% chlorantraniliprole·sanguisorbine sulfate suspension (effective concentration of chlorantraniliprole: 80 μg / ml; effective concentration of sanguisorbine sulfate: 1200 μg / ml) was sprayed. The control efficacy at 7 and 15 days post-application was 72.3% and 76.2%, respectively. A 2000-fold dilution of 20% chlorantraniliprole suspension (effective concentration: 100 μg / ml) and a 1000-fold dilution of 40% sanguisorbine sulfate wettable powder were applied using the same method. The control efficacy at 7 days post-application was 60.2% and 19.7%, respectively, and at 15 days post-application, it was 62.3% and 21.5%, respectively. The combination of chlorantraniliprole and sanguinarine sulfate has a significant synergistic effect, and its control effect on rice leaf roller is significantly better than that of single agents. Not only is the control effect improved, but the amount of active ingredient used is also significantly reduced compared to using them alone, which also reduces environmental pollution.

[0076] Field test examples In 2024, a demonstration field was established around Dukou in Gong'an County, Jingzhou City, Hubei Province. No rain fell during the trial period.

[0077] The experimental rice variety was Zhuliangyou 5298. Treatments from Examples 1-8 were sprayed, with the following dosages: Example 1: 17.1 ml / mu; Example 2: 11.3 ml / mu; Example 3: 15 ml / mu; Example 4: 7.2 ml / mu; Example 5: 7.2 ml / mu; Example 6: 12 ml / mu; Example 7: 18 ml / mu; Example 8: 22.5 ml / mu; 30% chlorantraniliprole suspension: 25 ml / mu; and 30% sanguisorbate sulfate wettable powder: 15 g / mu. Each treatment was applied at a rate of 15 L / mu. A blank control was included. Each treatment was replicated three times, with each replicate covering 0.5 mu.

[0078] The results are shown in Table 4.

[0079] Table 4. Results of the survey on rice yield and quality

[0080] In summary, this invention can prevent various lepidopteran pests with strong insecticidal effects, thus extending the control period and saving costs. Simultaneously, it can improve crop resistance and stimulate crop growth after pests and diseases occur, resulting in improved quality and increased yield.

[0081] The preferred embodiments of the present invention have been described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the scope of the technical concept of the present invention, various simple modifications can be made to the technical solution of the present invention, and these simple modifications all fall within the protection scope of the present invention.

[0082] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not describe the various possible combinations separately.

[0083] Furthermore, various different embodiments of the present invention can be combined in any way, as long as they do not violate the spirit of the present invention, they should also be regarded as the content of the present invention.

Claims

1. A pesticide insecticidal composition, characterized in that, The active ingredients include chlorantraniliprole and sanguinarine sulfate, with a weight ratio of chlorantraniliprole to sanguinarine sulfate of 99:1 to 1:

99.

2. The pesticide insecticidal composition according to claim 1, characterized in that, The weight ratio of chlorantraniliprole to sanguinarine sulfate is 20:1 to 1:20, optionally 10:1 to 1:10, optionally 5:1 to 1:5, optionally 5:1 to 1:3, optionally 3:1 to 1:3, optionally 20:1, 15:1, 10:1, 5:1, 3:1, 1:3, 1:5, 1:10, 1:15 or 1:

20.

3. The pesticide insecticidal composition according to claim 1 or 2, characterized in that, The active ingredient accounts for 1% to 90% of the total weight of the pesticide composition, optionally 16% to 50%.

4. The pesticide insecticidal composition according to any one of claims 1 to 3, characterized in that, It also includes additives, which are selected from one or more of the following: synergists, dispersants, wetting agents, binders, disintegrants, emulsifiers, stabilizers, antifreeze agents, defoamers, preservatives, thickeners, solvents, and dispersion media. And / or, the dosage form of the composition is at least one of the following: suspension concentrate, emulsifiable concentrate, microcapsule suspension, wettable powder, water-dispersible granules, microemulsion, and granules; preferably a suspension concentrate.

5. The pesticide insecticidal composition according to any one of claims 1 to 4, characterized in that, The raw materials include the following parts by weight: chlorantraniliprole 1-50 parts, sanguisorbine sulfate 1-50 parts, dispersant 1-10 parts, wetting agent 0-10 parts, thickener 0.1-5 parts, antifreeze agent 0-10 parts, and water 49-69 parts; Optionally, the raw materials include the following parts by weight: 1-40 parts of chlorantraniliprole, 1-40 parts of sanguisorbine sulfate, 4-10 parts of dispersant, 0-10 parts of wetting agent, 0.5-5 parts of thickener, 0-10 parts of antifreeze agent, and 49-69 parts of water; Optionally, water can be replenished to 100 servings.

6. The pesticide insecticidal composition according to claim 5, characterized in that, The dispersant includes one or more of sodium methylnaphthalene sulfonate formaldehyde condensate, sodium alkylnaphthalene sulfonate, sodium alkylnaphthalene sulfonate, and sodium lignin sulfonate; And / or, thickeners include xanthan gum; And / or, the wetting agent includes one or more of sodium butylnaphthalene sulfonate, sodium lauryl sulfate, sodium butylnaphthalene sulfonate, and sodium lauryl sulfate; And / or, antifreeze agents include one or more of glycerol and ethylene glycol.

7. A method for preparing the pesticide insecticidal composition according to claim 5 or 6, characterized in that, The active ingredients and adjuvants are mixed in proportion, subjected to high-speed shearing, wet milling, and finally homogenized filtration to obtain chlorantraniliprole·sanguinarine sulfate suspension.

8. The use of an insecticidal composition according to any one of claims 1 to 6 or an insecticidal composition prepared by the preparation method according to claim 7 in controlling pests and / or increasing crop yield.

9. The application according to claim 8, characterized in that, The pests include lepidopteran pests, and optionally, the lepidopteran pests are at least one of the following: rice stem borer, rice leaf roller, corn borer, armyworm, codling moth, beet armyworm, diamondback moth, and bollworm.

10. A method of using a pesticide insecticidal composition according to any one of claims 1 to 6 or a pesticide insecticidal composition prepared by the preparation method according to claim 7, characterized in that, The pesticide composition is applied to the pests that need to be controlled or their growth medium at an effective dose, optionally at an effective dose of 10-15 g / mu.

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