Single-stage negative oxygen ion flow device for purifying blood cells

Abstract

The invention discloses a single-stage negative oxygen ion flow device for purifying blood cells, which belongs to the technical field of electrotherapy, negative ion therapy and blood purification, and comprises a single-stage negative oxygen ion generation and targeted guide and grounding loop. According to the device, a high-purity negative oxygen ion flow with the particle size smaller than 0.01 mu m is generated through a single-stage negative high voltage and double shielding technology and enters a human body through skin / respiratory tract double paths, a device-human body-ground closed charge circulation loop is constructed, deep purification of blood cells is achieved through quadruple mechanisms such as cell membrane potential repair, and the purpose of purifying the blood cells is achieved. The device is suitable for household blood health care and auxiliary treatment of hyperviscosity and microcirculation disturbance of medical institutions, solves the problems of low ion purity, poor penetrability, target deficiency and the like of traditional equipment, and is high in safety and remarkable in purification effect.

Description

Technical Field

[0001] This invention relates to the fields of electrotherapy, negative ion therapy, and blood purification technology. Specifically, it relates to a single-stage negative oxygen ion flow device for purifying blood cells. Through the directional generation, targeted introduction, and closed-loop charge circulation of the single-stage negative oxygen ion flow, it achieves charge repair, free radical scavenging, red blood cell depolymerization, and metabolic activation of blood cells. It can be applied to home blood health care and as an adjunct treatment for diseases such as hyperviscosity syndrome / microcirculation disorders in medical institutions. Background Technology

[0002] Negative ion therapy, due to its drug-free and physical conditioning characteristics, is widely used in the fields of blood health maintenance and auxiliary treatment of microcirculation disorders. Existing negative ion generators and negative ion therapy devices mostly employ traditional bipolar discharge technology. However, this technology has many core defects in targeted blood cell purification applications, failing to achieve deep physical purification of blood cells. Specific problems are as follows:

[0003] Low ion purity and excessive harmful byproducts: Bipolar discharge technology generates an equal amount of positive ions while producing negative ions. The rapid neutralization of positive and negative ions causes a large loss of energy. In addition, the discharge process easily produces harmful byproducts such as ozone and nitrogen oxides. The ozone concentration often exceeds the national standard (>0.1mg / m³). Long-term inhalation can irritate the respiratory mucosa and even damage lung tissue, posing a health hazard.

[0004] Poor ionic properties and lack of biological penetration: The generated ions are mostly micron-sized large ion clusters, which cannot penetrate the gaps in the stratum corneum of human skin and the capillary barrier. They can only be adsorbed through the superficial layer of the respiratory tract and are difficult to enter the blood circulation, so they have no substantial conditioning effect on blood cells.

[0005] The mechanism of action is passive, with insufficient targeting and circulation: It adopts an open and divergent ion release method without a directional guidance mechanism. After the ion flow diffuses freely, the concentration decays rapidly, making it impossible to form a targeted effect on the human body. Furthermore, it has not established an in vivo and in vivo charge circulation pathway, and can only achieve the "surface effect" of ions, failing to solve the core problems of red blood cell aggregation and increased blood viscosity.

[0006] In summary, there is an urgent need for a device that can generate a high-purity, small-particle-size negative oxygen ion flow, and has directional guidance and closed-loop charge circulation, to fundamentally solve the problems of ion penetration, targeting, and safety, and achieve deep physical purification of blood cells. Summary of the Invention

[0007] The purpose of this invention is to overcome the technical defects of existing negative ion therapy devices and provide a single-stage negative oxygen ion flow device for purifying blood cells. By constructing an integrated closed-loop system of a single-stage negative oxygen ion generation module, a targeted guidance and grounding circuit module, it achieves high-concentration generation of pure negative oxygen ion flow, directional targeted introduction, and a closed charge cycle between the human body and the earth, fundamentally solving the problems of low ion purity, poor penetration, and lack of targeting. At the same time, through multiple safety monitoring and intelligent parameter control, it ensures the safety and adaptability of the device to different scenarios, achieving deep purification of blood cells and improvement of microcirculation, while also meeting the needs of home daily health care and medical auxiliary treatment.

[0008] To achieve the above objectives, this application adopts the following technical solution: This application provides a single-stage negative oxygen ion flow device for purifying blood cells, comprising: A single-stage negative oxygen ion generating module is used to generate a negative oxygen ion stream; The targeted guidance and grounding circuit module is used to form a closed charge circulation circuit with the human body and the earth, guiding the negative oxygen ion flow to enter the human body in a directional manner and form a circulation. The single-stage negative oxygen ion generating module includes: The emitter unit is used to excite electrons under high voltage, so that the electrons combine with oxygen molecules to generate negative oxygen ions; A high-voltage capacitor coupling circuit is connected to the emitter unit and is used to provide a high-frequency negative high voltage to the emitter unit; A shielding unit is used to cover the high-voltage capacitor coupling circuit and the emitter unit to isolate positive ions and electromagnetic radiation; The emitter unit includes an emitting needle, and the tip curvature radius of the emitting needle is within a preset range. The operating voltage of the high-voltage capacitor coupling circuit is within a preset voltage range, and the operating frequency is within a preset frequency range, so that the particle size of the generated negative oxygen ions is less than 0.01 micrometers.

[0009] Optionally, the emitter unit includes multiple emitter needles arranged in an array, and the emitter needles are made of nanoscale noble metal materials or carbon fibers, with a preset range of 0.1 to 0.5 micrometers corresponding to the radius of curvature of their needle tips.

[0010] Optionally, the high-voltage capacitor coupling circuit includes a high-frequency high-voltage transformer and a dielectric capacitor, with a preset voltage range of -3kV to -40kV for its operating voltage and a preset frequency range of 20kHz to 100kHz for its operating frequency.

[0011] Optionally, the shielding unit includes: The circuit shielding layer is formed by covering the high-voltage capacitor coupling circuit with a conductive material and grounded; A structural shield is disposed outside the emitter unit and grounded, and the structural shield has an outlet for directional output of negative oxygen ion flow.

[0012] Optionally, the target guidance and grounding loop module includes: A directional transmitting antenna is electrically connected to the single-stage negative oxygen ion generating module to form a unipolar electrostatic field that guides the flow of negative oxygen ions toward the human body. Human body grounding components are used to electrically connect the user to the earth; The device forms an electrical connection with the human body grounding component and the earth through the ground port of its power plug to construct the closed charge loop.

[0013] Optionally, the human body grounding component is a grounding pad made of conductive rubber, a grounding wristband with a built-in conductive layer, or a grounding foot ring with a built-in conductive layer, and its grounding resistance meets the requirement of forming a low-potential connection with the earth.

[0014] Optionally, it also includes an intelligent control and safety monitoring module, which includes a microcontroller and one or more of an ozone sensor, a microcurrent sensor and a temperature sensor connected to the microcontroller; The microcontroller automatically adjusts the output parameters of the single-stage negative oxygen ion generating module or performs protection operations based on the monitoring data from the connected sensors.

[0015] Optionally, the ozone sensor is used to monitor the ozone concentration in real time, and the microcontroller is preset with a safety threshold of no more than 0.003 mg / m³; when the ozone concentration monitoring value meets the set relationship with the safety threshold, the microcontroller controls the reduction of high voltage output or cuts off the power supply of the single-stage negative oxygen ion generating module.

[0016] Optionally, the microcurrent sensor is connected to the target guidance and grounding loop module to detect the loop current of the closed charge circulation loop; when no loop current is detected, the microcontroller prevents the single-stage negative oxygen ion generation module from starting.

[0017] Compared with the prior art, this application has the following beneficial effects: 1. Achieve high-purity, small-particle-size pure negative oxygen ion flow generation: Through single-stage negative high-voltage power supply and "circuit + structure" dual shielding technology (shielding the high-voltage capacitor coupling circuit and the emitter unit respectively), the generation of positive ions is completely isolated, achieving the generation of high-purity negative oxygen ion flow. Moreover, the generated negative oxygen ion particle size is less than 0.01 micrometers, with extremely strong biological penetrability. It can directly penetrate the stratum corneum and capillary barrier of the skin and enter the blood circulation, fundamentally solving the core defects of low ion purity and poor penetrability of traditional technologies.

[0018] 2. Constructing a targeted closed charge cycle with significant purification effect: By guiding the ion flow and combining it with the closed charge cycle loop of the human body-earth, a piroampere-level microcurrent closed loop is established, which is "device → human body → earth → device". This allows the negative oxygen ion flow to complete charge replenishment and free radical removal in the blood and then flow back in an orderly manner, achieving deep purification of blood cells. It can effectively reduce blood viscosity, deaggregate red blood cells, and improve microcirculation perfusion, and has a significant auxiliary therapeutic effect on hyperviscosity syndrome and microcirculation disorders.

[0019] 3. No drug intervention, high biosafety: This device purifies blood cells through physical means, without drug intervention or invasive operation, and will not produce toxic side effects on the human body. Moreover, after the negative oxygen ion flow enters the human body, there is no residue. After charge circulation, the excess negative charge flows back to the earth in an orderly manner, without damaging human tissues and organs. Attached Figure Description

[0020] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with this application and, together with the description, serve to explain the principles of this application. Furthermore, these drawings and textual descriptions are not intended to limit the scope of the concept in any way, but rather to illustrate the concepts of this application to those skilled in the art through reference to specific embodiments.

[0021] Figure 1 This application provides a schematic diagram of the internal module electrical connections of a single-stage negative oxygen ion flow device for purifying blood cells. Figure 2 This is a schematic diagram illustrating the working principle of a single-stage negative oxygen ion flow device for purifying blood cells, provided in an embodiment of this application. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of this application clearer, the technical solutions in the embodiments of this application will be clearly and completely described below in conjunction with the embodiments of this application. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application. Unless otherwise specified, the following embodiments and features can be combined with each other.

[0023] Reference Figure 1 and Figure 2 The present invention relates to a single-stage negative oxygen ion flow device for purifying blood cells. The core of the device includes a single-stage negative oxygen ion generation module and a targeted guidance and grounding circuit module. Optional modules include an intelligent control and safety monitoring module and a human-machine interaction module. The modules are electrically connected to form an integrated closed-loop system. The specific structure, implementation details, working parameters and core functions of each module are described in detail below.

[0024] The single-stage negative oxygen ion generation module is the core ion generation unit of this device, used to generate a pure negative oxygen ion stream that is free of positive ions and ozone, with a particle size of less than 0.01 micrometers. It includes an emitter unit, a high-voltage capacitor coupling circuit, and a shielding unit, which work together to achieve the stable generation of a high-concentration, high-purity, small-particle-size negative oxygen ion stream.

[0025] The emitter unit is used to excite free electrons under high-frequency negative high voltage, allowing these free electrons to combine with neutral oxygen molecules in the air to generate negative oxygen ions. Its structure and material design directly determine the ion generation efficiency and particle size. To ensure that the generated negative oxygen ions have a particle size of less than 0.01 micrometers (the diameter of human capillaries is about 3 micrometers; negative oxygen ions of this size can quickly penetrate human capillaries), the specific structural design of the emitter unit is as follows: Core components include multiple emission needles, which are made of nanoscale precious metal materials or carbon fiber; among them, the nanoscale precious metal materials are preferably 99.99% nano-gold needles or Pt90% Ir10% platinum-iridium alloy needles. The gold needle has an electron work function as low as 4.8eV, which can excite high-density electrons at a relatively low voltage, and it is chemically stable with no metal volatilization; the platinum-iridium alloy needle has a resistivity ≤1.0×10^-7Ω. m, with excellent conductivity and corrosion resistance, is suitable for high-frequency medical applications; carbon fiber material is lightweight and has high electron emission efficiency, making it a preferred alternative for home use.

[0026] Structural parameters: Multiple emitting needles are arranged in a matrix (e.g., 4×4 / 6×6, etc.), and the tip curvature radius is strictly controlled within a preset range, specifically 0.1 to 0.5 micrometers in some embodiments, to form a strong electric field tip effect and ensure efficient electron escape; the needle spacing is controlled at 2-3 mm to avoid ion loss caused by electric field interference between electrodes.

[0027] Preparation and Installation: The nanoscale gold needle is deposited with a gold layer on a tungsten steel needle substrate (0.1 mm in diameter) using vacuum magnetron sputtering. The gold layer thickness is controlled between 50-100 nm to ensure stable electron work function and prevent coating peeling. The platinum-iridium alloy needle is precision forged, and the needle tip is laser-polished to ensure accurate curvature radius. The carbon fiber emitting needle is molded, and the needle tip is sharpened. The entire emitting needle is fixed to a high-temperature resistant insulating ceramic base (temperature resistance ≥200℃, resistivity ≥10^14Ω). (m) A polytetrafluoroethylene insulating pad is used to isolate the ceramic base from the high-voltage circuit to prevent high-voltage leakage.

[0028] The high-voltage capacitor coupling circuit is electrically connected to the emitter unit to provide a stable high-frequency negative high voltage to the emitter unit, providing energy for electron escape. It is the core power unit for generating small-particle negative oxygen ions, and the specific design is as follows: Circuit topology: A coupling structure of high-frequency high-voltage transformer + dielectric capacitor + rectifier and filter unit is adopted to achieve low-loss and highly stable negative high-voltage output; among which, the dielectric capacitor is preferably a polytetrafluoroethylene high-voltage capacitor with a withstand voltage of ≥15kV, capacitance of 0.1μF, and low dielectric loss (tanδ≤0.001), ensuring capacitor stability at high frequencies; the rectifier and filter unit adopts high-voltage silicon stack rectification, combined with ceramic filter capacitor, to achieve smooth negative high-voltage output.

[0029] Key operating parameters: The preset operating voltage range is -3kV to -40kV, the preset operating frequency range is 20kHz to 100kHz, and the duty cycle is 50%. This parameter range effectively allows free electrons to fully combine with neutral oxygen molecules to generate small-particle O2. - H2O ion clusters ensure that the ion particle size is less than 0.01 micrometers.

[0030] Overvoltage protection design: A Zener diode (regulated voltage -40.5kV) and a resettable fuse (rated current 50mA) are connected in series in the circuit. When the voltage is overloaded, the diode breaks down in reverse to release the voltage, and the fuse automatically disconnects to prevent the high-frequency high voltage transformer from burning out and abnormal ion flow from being generated, thus ensuring the safe use of the circuit and device.

[0031] The shielding unit is used to cover the high-voltage capacitor coupling circuit and the emitter unit, achieving positive ion isolation and electromagnetic radiation shielding. It adopts a dual shielding technology of "circuit shielding layer + structural shielding cover", and the specific design is as follows: Circuit shielding layer: The high-voltage capacitor coupling circuit is completely wrapped with a 30μm thick conductive material (preferably copper foil). The conductive material is directly grounded to form an electrostatic shielding layer to prevent the circuit from radiating a positive electric field and avoid the generation of positive ions.

[0032] Structural shielding cover: An annular metal shielding cover is set on the outside of the emitter unit. The shielding cover is directly grounded and has a directional ion flow outlet (e.g., 5mm aperture). Only negative oxygen ion flow is allowed to be directionally output through the outlet, eliminating the leakage of stray positive ions, and further shielding the electromagnetic radiation of the emitter unit.

[0033] Electric field calibration: Before the device leaves the factory, the electric field around the emitter is calibrated by a high-precision electric field meter to ensure that after the shielding treatment, there is basically only a pure negative electrostatic field outside the emitter, and the positive electric field strength is 0 or close to 0, so as to ensure that the generated ion flow is a high-purity negative oxygen ion flow.

[0034] Secondly, the targeted guidance and grounding loop module is the core unit for the directional introduction and charge circulation of negative oxygen ion flow. It is used to form a closed charge circulation loop with the human body and the earth, guiding the negative oxygen ion flow to actively target and enter the human body and complete the charge circulation, solving the problem of "passive diffusion and no circulation" in traditional technology. It includes a directional transmitting antenna and a human body grounding component. The two work together with the device's power ground wire to construct a complete closed charge circulation loop.

[0035] The directional transmitting antenna is electrically connected to the single-stage negative oxygen ion generating module to form a unipolar negative electrostatic field, providing a directional driving force for the negative oxygen ion flow, thus changing the ion flow from free diffusion to active targeted transmission. The specific design of the directional transmitting antenna is as follows: Structure and materials: A ring-shaped aluminum directional transmitting antenna (8-12cm in diameter) is used, with a hard anodized insulating treatment on the surface (10μm oxide layer thickness), which ensures the stable formation of the electrostatic field and avoids the risk of electric shock from human contact.

[0036] Installation and electric field parameters: The distance between the antenna and the emitter unit is controlled at 5-8cm, and the angle of the directional negative electrostatic field formed is 60-90°, which ensures both the effective coverage range of the ion flow (diameter 1-1.5m) and the directionality, and reduces the diffusion loss of the ion flow.

[0037] Power supply and isolation: The antenna is powered by 12V DC low voltage and is electrically isolated from the high voltage capacitor coupling circuit through an optocoupler to avoid electromagnetic interference from the high voltage module and ensure the stability of the directional negative electrostatic field.

[0038] Ion flow acceleration mechanism: The directional negative electrostatic field generates electrostatic repulsion on the negatively charged oxygen ion flow, causing the ion flow to form a directional high-speed "ion wind" of 0.5-1m / s, which actively tends towards the human body with a positive potential / grounded. The ion flow transmission efficiency is more than 80% higher than that of traditional open release.

[0039] The human body grounding component is used to electrically connect the user to the earth and is a key component in constructing a closed charge circulation loop. The specific design of the human body grounding component is as follows: Component types include grounding mats made of conductive rubber, grounding wristbands or grounding ankle rings with built-in conductive layers, adaptable to different usage postures and scenarios; the grounding mats have a surface resistivity of ≤10^6Ω, and are available in sizes of 30×40cm (suitable for standing scenarios) or 60×180cm (suitable for lying scenarios), with a built-in copper foil conductive layer (0.1mm thick) and an anti-slip textured surface; the grounding wristbands / grounding ankle rings are made of food-grade silicone, with a built-in silver fiber conductive layer (contact resistance ≤100Ω), and are equipped with adjustable buckles and anti-breakage aviation connectors, suitable for sitting, lying and other scenarios.

[0040] Grounding connection requirements: The human body grounding component is connected to the grounding port of the device through a copper core grounding wire (wire diameter ≥ 0.5mm²). The device adopts a national standard 10A three-prong power plug, and its grounding port is directly connected to the earth through a 2.5mm² copper core wire. The overall grounding resistance is ≤ 4Ω, which meets the requirement of forming a low potential connection with the earth and ensures that the human body forms a low potential connection with the earth, providing a smooth channel for charge circulation.

[0041] Based on the above device, the closed charge circulation loop and ion flow permeation mechanism are as follows: The device is electrically connected to the grounding component of the human body and the earth through the grounding port of the power plug, thus constructing a closed charge loop of "single-stage negative oxygen ion generation module → directional transmitting antenna → human body → earth → device". The negative oxygen ion flow carries a negative potential and forms a potential difference with the grounded human body (0V), driving the negative oxygen ion flow into the human body. Excess negative charge flows to the earth through the human body grounding component and finally flows back to the device, forming a micro-current closed loop with a current of <100pA, which is completely harmless to the human body.

[0042] Dual Ion Flow Permeation Path: The generated negative oxygen ion flow has a particle size of less than 0.01 micrometers, possessing extremely strong biological penetrability. It can enter the human blood circulation through a dual pathway of skin penetration and respiratory tract penetration (the diameter of human capillaries is about 3 micrometers, while the diameter of commercially available bipolar ions is generally about 12-15 micrometers, which cannot penetrate the skin and capillaries). The bioavailability is improved by more than 90% compared to traditional technologies. In the skin penetration pathway, the negative oxygen ion flow enters the dermis through the gaps in the stratum corneum of the skin, and directly enters the systemic circulation through the capillaries of the dermis. In the respiratory tract penetration pathway, the negative oxygen ion flow enters the pulmonary circulation through the gas exchange membrane of the alveolar wall, and after binding with hemoglobin, it is transported to tissues throughout the body.

[0043] Based on the above principles, this device achieves deep purification of blood cells through a closed charge circulation loop and directional ion flow introduction. Its core mechanism is based on a four-pronged approach: cell membrane potential repair, reactive oxygen species scavenging, erythrocyte depolymerization, and blood cell metabolic activation. These four mechanisms work synergistically to optimize blood cell function and improve microcirculation. Cell membrane potential repair: Normal blood cells (red blood cells, vascular endothelial cells) carry a negative charge on their surface. Under pathological conditions, the cell potential decreases or even becomes positively charged, leading to abnormal cell function. Negative oxygen ion flow replenishes cells with a large number of free electrons, restores the normal polarization state of the cell membrane, rebuilds the sodium-potassium-ATPase ion channel, promotes the transmembrane transport of potassium, sodium, and calcium ions, and restores the normal physiological function of blood cells and vascular endothelial cells.

[0044] Scavenging of reactive oxygen species: Reactive oxygen species in the body are positively charged / uncharged oxidizing substances, which are the core factors leading to oxidative damage to red blood cell membranes and aging of vascular endothelium. The free electrons provided by the negative oxygen ion flow react with the free radicals in an oxidation-reduction reaction, reducing them to stable water molecules (H2O) and oxygen molecules (O2), fundamentally reducing the damage of free radicals to blood cells and blood vessels.

[0045] Red blood cell deagglomeration and reduced blood viscosity: The core reason for red blood cell aggregation is the loss of negative charge on its surface, which causes the electrostatic attraction between cells to be greater than the repulsion. The flow of negative oxygen ions replenishes the negative charge of red blood cells, and uses the principle of like charges repulsion to deagglomerate the aggregated red blood cell clusters. At the same time, it repairs the flexibility of the red blood cell membrane, improves the deformability of red blood cells, reduces the apparent viscosity of blood, and promotes the flow of blood in the microcirculation.

[0046] Blood cell metabolism activation: After negative oxygen ions enter the human body, they repair and activate the mitochondrial respiratory chain in cells through cell membrane potential repair, promote ATP synthesis, and improve the energy metabolism level of blood cells; at the same time, they activate the proliferation and differentiation capacity of bone marrow hematopoietic stem cells, improve the production and metabolism of red blood cells and white blood cells, and enhance the oxygen-carrying capacity and immune function of blood; in addition, they can also activate the normal contraction and relaxation of vascular smooth muscle cells, improve vascular elasticity, and relieve microcirculation disorders.

[0047] To enhance device functionality and user experience, in some embodiments, the single-stage negative oxygen ion flow device may also include an intelligent control and safety monitoring module.

[0048] The intelligent control and safety monitoring module is the core unit for the device's intelligent regulation and multiple safety protections. It includes a microcontroller and sensors electrically connected to the microcontroller. The sensors include one or more high-precision sensors such as ozone sensors, microcurrent sensors, and temperature sensors. The microcontroller enables dynamic adjustment of ion concentration, multi-dimensional safety monitoring, and automatic fault protection, thus mitigating usage risks from the outset.

[0049] 1. Core control components Microcontroller: The STM32F103C8T6 microcontroller is selected, which features low power consumption (standby current <1μA) and high computing speed (72MHz). It supports multi-channel data acquisition and precise PWM output, providing core computing power for the intelligent control of the device. The built-in PID closed-loop control algorithm can adjust the PWM output duty cycle of the high-voltage capacitor coupling circuit in real time according to the preset ion concentration or sensor monitoring data, with a concentration adjustment accuracy of ±5%, avoiding ion concentration fluctuations.

[0050] Sensor group: including ozone sensor, micro current sensor, temperature sensor, current transformer, etc. All sensors are high-precision models with a data sampling frequency of ≥1 time / second, providing accurate data support for safety monitoring.

[0051] 2. Core intelligent control function The microcontroller uses a PID closed-loop control algorithm to precisely adjust the device's operating parameters, supporting both scenario-based preset modes and medical-customized modes. Negative oxygen ion concentration, operating voltage, and operating frequency can all be adjusted according to needs, adapting to different users and scenarios. Daily health care mode: Suitable for daily blood maintenance for healthy people, negative oxygen ion concentration of 2 million to 100 million / cm³, working voltage -3kV to -10kV, working frequency 20kHz to 30kHz, recommended usage time 10-20 minutes / time; Deep purification mode: Suitable for people with hyperviscosity syndrome / microcirculation disorders, negative oxygen ion concentration of 10 billion to 60 billion ions / cm³, working voltage -20kV to -40kV, working frequency 50kHz to 100kHz, recommended usage time 30-60 minutes / time. Medical Customization Mode: Suitable for personalized treatment in medical institutions. The concentration of negative oxygen ions is 2 million to 60 billion / cm³, the working voltage is -3kV to -40kV, and the working frequency is 20kHz to 100kHz, all of which can be freely adjusted. The parameters are set by medical staff according to the patient's blood indicators and physical condition.

[0052] 3. Multiple security monitoring and protection mechanisms Based on the monitoring data from each sensor, the microcontroller automatically adjusts the output parameters of the single-stage negative ion generating module or executes protective operations such as shutdown and alarm, achieving comprehensive safety protection. The core protection mechanism is as follows: Real-time ozone monitoring and protection: Built-in MQ-131 high-precision ozone sensor with a detection accuracy of 0.001 mg / m³, used for real-time monitoring of ozone concentration. The microcontroller has a preset ozone safety threshold of no more than 0.003 mg / m³. When the ozone concentration monitoring value meets the set relationship with the safety threshold; specifically, when the monitoring value is close to (the difference is considered close if it is less than the set value) but does not exceed the safety threshold, the microcontroller automatically reduces the output voltage of the high-voltage capacitor coupling circuit; if the monitoring value exceeds the safety threshold, the power supply of the single-stage negative oxygen ion generation module is immediately cut off, and a buzzer (80dB) and LED red light flashing alarm are triggered until the ozone concentration drops to a safe range.

[0053] Grounding continuity monitoring and protection: The micro-current sensor is electrically connected to the target guidance and grounding loop module to detect the micro-current of the closed charge circulation loop in real time. When no loop current is detected (human body is not grounded), the microcontroller prohibits the single-stage negative oxygen ion generation module from starting and provides an LED yellow light to avoid the risk of static electricity generated by the accumulation of ion flow on the human body surface when there is no grounding.

[0054] Over-temperature protection: An NTC thermistor (temperature range -20~120℃) is installed at both the high-voltage capacitor coupling circuit and the ceramic base of the emitter unit to monitor the temperature of the core components of the device in real time; when the temperature exceeds 60℃, the microcontroller automatically reduces the power of the device; when the temperature exceeds 70℃, the device will stop immediately and trigger an alarm to prevent overheating damage.

[0055] Overcurrent protection: A current transformer is added to the power supply end of the device to monitor the operating current in real time; when the operating current exceeds 500mA, the self-resetting fuse will automatically disconnect and cut off the power supply to prevent short circuit faults.

[0056] Electromagnetic radiation shielding: The whole machine is made of 1.5mm cold-rolled steel plate shell, and the inside is covered with conductive cloth electromagnetic shielding foam (shielding effectiveness ≥60dB). The high-voltage capacitor coupling circuit and the control module are isolated by metal partition. The electromagnetic radiation power density at 1m around the device is <0.5W / m², which is far lower than the national standard <2W / m².

[0057] Timed shutdown protection: The microcontroller has a built-in timer function (adjustable from 10 to 60 minutes), which automatically shuts down after the set usage time to avoid excessive replenishment of human body charge due to prolonged use.

[0058] In addition, the device adopts a compact desktop design, with overall dimensions of 25×20×15cm. Its rounded corners and non-slip rubber base facilitate both home placement and medical portability. The core structural design is as follows: Shell material: The shell is made of cold-rolled steel plate and treated with electrostatic powder coating, which is scratch-resistant, corrosion-resistant, and has electromagnetic radiation shielding effect. Air outlet: Located on the front of the device, using insulated ABS grilles (1mm grille spacing), which can rotate 360° (adjustable angle 0-90°) to accommodate different usage postures such as lying down, standing, and sitting, ensuring that the ion flow is accurately aligned with the human body; Power supply: 220V / 50Hz AC mains power supply, built-in power adapter (output 12VDC + high voltage), total power ≤50W, low power consumption and energy saving; Interface layout: The power interface, grounding interface, and antenna interface are located on the back of the device. All interfaces are waterproof and insulated, making them safe and convenient to use.

[0059] In addition, the device can be equipped with a human-computer interaction module, which serves as the user's entry point for operation and information interaction with the device. The module is designed to be simple and easy to understand, and is suitable for users of different ages. The core components are as follows: Display unit: Equipped with a 2.4-inch LCD screen, which displays parameters such as negative oxygen ion concentration, working voltage, working frequency, ozone concentration, working time, and equipment status (normal / prompt / alarm) in real time, and the data is intuitive and visible; Operating unit: It is equipped with 4 backlit touch buttons (power, mode, duration, and adjustment), which support mode switching, usage time setting, and parameter fine-tuning. The buttons are highly sensitive and easy to use in low-light environments. Alarm unit: Equipped with a buzzer and a three-color LED indicator. Green indicates that the equipment is working normally, yellow indicates grounding abnormality and other prompts, and red indicates ozone exceeding the standard, over-temperature and other alarms. It provides multi-dimensional prompts on the equipment status, allowing users to keep track of the device's operation in a timely manner.

[0060] The device of this invention is easy to operate and requires no professional skills. It is divided into home use and medical use methods according to the application scenario. Both methods follow the core process of "grounding → parameter setting → startup → shutdown," as detailed below: 1. Instructions for home use (suitable for healthy individuals / people with mild hyperviscosity syndrome) Equipment placement: Place the device on a stable, well-ventilated table, 0.5-1m away from people, and keep it at least 1m away from high-voltage equipment such as microwave ovens and induction cookers to avoid electromagnetic interference; Grounding preparation: Lay a dedicated grounding mat on a dry surface and connect the grounding device to the grounding interface via a grounding wire; the user should stand barefoot on the grounding mat (or wear a grounding wristband and connect the device) to ensure effective grounding between the human body and the earth; Power-on setup: Connect to 220V AC mains power, press the power button, select daily health care mode / deep purification mode via touch buttons, set the usage time (10-60 minutes), and rotate the air outlet to direct it towards the human torso; Start-up and use: Press the start button to start the device. The LCD screen will display the operating parameters in real time. During use, keep the room well-ventilated and avoid touching the air outlet and high-pressure components of the device. End of operation: After the set time is reached, the device will automatically stop; wait 3 minutes (when the residual charge of the device is completely released) before disconnecting the power supply and grounding connection, and clean the grounding pad / wristband for later use.

[0061] 2. Medical Application Instructions (Suitable for use in hospital rehabilitation departments / geriatric departments, as an adjunct treatment for hyperviscosity syndrome / microcirculatory disorders) Preoperative assessment: Medical staff determine the treatment mode and core parameters (negative oxygen ion concentration, working voltage, treatment duration) based on the patient's blood indicators (blood viscosity, erythrocyte aggregation index) and physical condition. Equipment debugging: Place the device next to the treatment bed, connect the ground wire to the dedicated grounding wristband, start the device and enter the medical customized mode, adjust the parameters and save them through the touch button or remote debugging tool; Treatment procedure: The patient wears a grounding wristband and sits / lies on the treatment bed. Point the device's air outlet at the patient and start the device. During the treatment, monitor the patient's vital signs (heart rate, blood pressure) and the device's operating parameters in real time to ensure treatment safety. Treatment course settings: Each treatment lasts 30-60 minutes, once a day, and 10 treatments constitute one course of treatment; after the course of treatment, the patient's blood indicators should be checked again, and subsequent treatment parameters should be adjusted according to the results; Postoperative care: After treatment, have the patient sit quietly for 5 minutes before getting up to avoid orthostatic hypotension; clean the grounding wristband promptly, disinfect it, and keep it for future use.

[0062] In summary, the device of this invention can achieve deep purification of blood cells through physical means, without drug intervention or side effects. It solves the core technical defects of existing negative ion therapy equipment, and provides a brand-new technical solution for blood health maintenance and auxiliary treatment of microcirculation disorders. It has significant industrial application value and social value.

[0063] It is understood that the same or similar parts in the above embodiments can be referred to each other, and the contents not described in detail in some embodiments can be referred to the same or similar contents in other embodiments.

[0064] It should be noted that in the description of this application, the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance. Furthermore, in the description of this application, unless otherwise stated, "a plurality of" means at least two.

[0065] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0066] Although embodiments of this application have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting this application. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of this application.

Claims

1. A single-stage negative oxygen ion flow device for purifying blood cells, characterized in that, include: A single-stage negative oxygen ion generating module is used to generate a negative oxygen ion stream; The targeted guidance and grounding circuit module is used to form a closed charge circulation circuit with the human body and the earth, guiding the negative oxygen ion flow to enter the human body in a directional manner and form a circulation. The single-stage negative oxygen ion generating module includes: The emitter unit is used to excite electrons under high voltage, so that the electrons combine with oxygen molecules to generate negative oxygen ions; A high-voltage capacitor coupling circuit is connected to the emitter unit and is used to provide a high-frequency negative high voltage to the emitter unit; A shielding unit is used to cover the high-voltage capacitor coupling circuit and the emitter unit to isolate positive ions and electromagnetic radiation; The emitter unit includes an emitting needle, and the tip curvature radius of the emitting needle is within a preset range. The operating voltage of the high-voltage capacitor coupling circuit is within a preset voltage range, and the operating frequency is within a preset frequency range, so that the particle size of the generated negative oxygen ions is less than 0.01 micrometers.

2. The apparatus according to claim 1, characterized in that, The emitter unit includes multiple emitter needles arranged in an array. The emitter needles are made of nanoscale precious metal materials or carbon fibers, and the preset range of their tip curvature radius is 0.1 to 0.5 micrometers.

3. The apparatus according to claim 1, characterized in that, The high-voltage capacitor coupling circuit includes a high-frequency high-voltage transformer and a dielectric capacitor. The preset voltage range corresponding to the operating voltage of the high-voltage capacitor coupling circuit is -3kV to -40kV, and the preset frequency range corresponding to the operating frequency is 20kHz to 100kHz.

4. The apparatus according to claim 1, characterized in that, The shielding unit includes: The circuit shielding layer is formed by covering the high-voltage capacitor coupling circuit with a conductive material and grounded; A structural shield is disposed outside the emitter unit and grounded, and the structural shield has an outlet for directional output of negative oxygen ion flow.

5. The apparatus according to claim 1, characterized in that, The target guidance and grounding loop module includes: A directional transmitting antenna is electrically connected to the single-stage negative oxygen ion generating module to form a unipolar electrostatic field that guides the flow of negative oxygen ions toward the human body. Human body grounding components are used to electrically connect the user to the earth; The device forms an electrical connection with the human body grounding component and the earth through the ground port of its power plug to construct the closed charge loop.

6. The apparatus according to claim 5, characterized in that, The human body grounding component is a grounding pad made of conductive rubber, a grounding wristband with a built-in conductive layer, or a grounding foot ring with a built-in conductive layer, and its grounding resistance meets the requirement of forming a low-potential connection with the earth.

7. The apparatus according to claim 1, characterized in that, It also includes an intelligent control and safety monitoring module, which includes a microcontroller and one or more of an ozone sensor, a microcurrent sensor and a temperature sensor connected to the microcontroller; The microcontroller automatically adjusts the output parameters of the single-stage negative oxygen ion generating module or performs protection operations based on the monitoring data from the connected sensors.

8. The apparatus according to claim 7, characterized in that, The ozone sensor is used to monitor ozone concentration in real time. The microcontroller has a preset safety threshold of no more than 0.003 mg / m³. When the ozone concentration monitoring value meets the set relationship with the safety threshold, the microcontroller controls the reduction of high voltage output or cuts off the power supply of the single-stage negative oxygen ion generating module.

9. The apparatus according to claim 7, characterized in that, The microcurrent sensor is connected to the target guidance and grounding loop module to detect the loop current of the closed charge circulation loop; when no loop current is detected, the microcontroller disables the single-stage negative oxygen ion generation module from starting.

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