Targeted aerosol inhalation administration device for acute lung injury
By designing a preheating and status assessment system for the nebulizer, the discomfort caused by low-temperature airflow was resolved, achieving suitable airflow temperature and improved drug utilization, thereby enhancing patient tolerance and treatment effectiveness.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- CHONGQING UNIV OF TECH
- Filing Date
- 2026-03-06
- Publication Date
- 2026-05-01
AI Technical Summary
Existing nebulizers have low airflow temperatures in winter, which can easily cause discomfort to patients if inhaled directly, especially those with lung damage, COPD, and asthma. Furthermore, the operating status of the device is difficult to judge intuitively, resulting in serious waste of medication.
A targeted nebulization inhalation drug delivery device was designed, which includes a preheating mechanism and a nebulization mechanism. The water bath in the heating frame preheats the connecting pipe to ensure a suitable airflow temperature. A fan blade is set at the top of the nebulization cup to judge the device's operating status, and a scraper collects the drug liquid, thereby achieving stable airflow and improved drug utilization.
It effectively avoids airway irritation from cold mist, reduces discomfort symptoms such as coughing and airway spasms, improves patient tolerance and treatment comfort, increases drug utilization, and ensures drug administration stability and quality.
Smart Images

Figure CN121944313A_ABST
Abstract
Description
A targeted nebulized inhalation drug delivery device for acute lung injury Technical Field
[0001] This invention relates to the field of nebulized inhalation equipment technology, specifically a targeted nebulized inhalation drug delivery device for acute lung injury. Background Technology
[0002] Targeted nebulized inhalation drug delivery devices are specialized medical devices that precisely control aerosol particle size, release timing, and airflow parameters to allow drugs to be deposited in specific parts of the respiratory tract (nasal cavity, pharynx, bronchi, alveoli). They can significantly increase local drug concentration, reduce systemic drug dosage and side effects, and are widely used for asthma, COPD, sinusitis, lung infections, etc.
[0003] Nebulized inhalation drug delivery devices deliver medication to patients by atomizing the liquid. However, the tubing of existing nebulizers is often directly exposed, resulting in low-temperature airflow. Especially in winter, direct inhalation of cold gas can easily cause discomfort and increase irritation responses such as sneezing and coughing. This has a more significant impact on patients with lung injury, COPD, or asthma. Therefore, to address these issues, a targeted nebulized inhalation drug delivery device for acute lung injury is proposed. Summary of the Invention
[0004] The purpose of this invention is to provide a targeted nebulized inhalation drug delivery device for acute lung injury, so as to solve the problems mentioned in the background art.
[0005] To achieve the above objectives, the present invention provides the following technical solution: As an optional solution of the targeted nebulized inhalation drug delivery device for acute lung injury described in the present invention, wherein: a targeted nebulized inhalation drug delivery device for acute lung injury includes a nebulizer, a connecting tube, a preheating mechanism, and a nebulizing mechanism; a preheating mechanism is installed above the nebulizer, and a connecting tube is provided inside the preheating mechanism, one end of the connecting tube is connected to the nebulizer, and the other end of the connecting tube is connected to the nebulizing mechanism; the preheating mechanism includes a heating frame fixedly connected to the nebulizer, a base plate is provided inside the heating frame, multiple guide grooves are opened inside the base plate, and springs are provided inside each guide groove, one end of the spring is fixedly connected to a moving column, and the other end of the spring is fixedly connected to the inner wall of the heating frame; a limit plate is fixedly connected to the top of each moving column; one side of the heating frame is fixedly connected to the connecting tube.
[0006] Nebulized inhalation drug delivery devices deliver medication by atomizing it for inhalation. Existing nebulizers often have exposed tubing, resulting in low airflow temperatures. Especially in winter, direct inhalation of cold gas can easily cause discomfort, increasing irritation such as sneezing and coughing. This has a more significant impact on patients with lung damage, COPD, and asthma. This device places the connecting tube on one side of the moving column, using multiple guide grooves to compress the moving column and thus limit and fix the connecting tube. The heating frame contains heating elements and water. Heating the water creates a water bath environment to preheat the connecting tube, ensuring a suitable airflow temperature. This avoids cold mist irritating the airways, reducing discomfort such as coughing and bronchospasm, and improving the tolerance of children, the elderly, COPD patients, and asthma patients. The staggered arrangement of multiple moving columns extends the travel distance and heating area of the connecting tube within the heating frame, further ensuring effective gas preheating.
[0007] As an optional embodiment of the targeted nebulized inhalation drug delivery device for acute lung injury described in this invention, the nebulization mechanism includes a nebulizing cup, one end of which is connected to a connecting tube, and a mask is also installed on one side of the nebulizing cup; a rotating shaft is rotatably connected above the nebulizing cup, a driven fan blade is fixedly connected to the top of the rotating shaft, and an active fan blade is fixedly connected to the bottom of the rotating shaft, with the active fan blade disposed inside the transverse tube of the nebulizing cup.
[0008] A guide cover is also provided on the outside of the active fan blade, and the guide cover is fixedly connected to the inside of the atomizing cup.
[0009] As an alternative embodiment of the targeted nebulized inhalation drug delivery device for acute lung injury described in this invention, the guide cover is arranged in an arc shape.
[0010] As an optional embodiment of the targeted nebulized inhalation drug delivery device for acute lung injury described in this invention, wherein: an adjustment disc is provided at the bottom of the nebulizer cup, a connecting column is fixedly connected to the top of the adjustment disc, and the outer side of the connecting column is rotatably connected to the nebulizer cup; a connecting rod is fixedly connected to one side of the connecting column, and a scraper is fixedly connected to the other end of the connecting rod.
[0011] As an alternative embodiment of the targeted nebulized inhalation drug delivery device for acute lung injury described in this invention, the scraper is arranged in a spiral, and the outer side of the scraper is fitted against the inner wall of the nebulization cup.
[0012] The gas produced by nebulization is mostly transparent and only appears as a mist inside the nebulization mechanism. It is difficult to intuitively judge whether the airflow in the connecting tube and the nebulization cup is normal, and it is impossible to accurately confirm the operating status of the equipment. Therefore, a rotating shaft, driven fan blades and active fan blades are set at the top of the nebulization cup. When the airflow flows, it can drive the active fan blades to rotate, which in turn drives the driven fan blades to rotate, so as to intuitively judge the operating status of the equipment and ensure the stability and quality of drug administration.
[0013] After atomization, a large amount of liquid medicine droplets tend to adhere to the inner wall of the atomizing cup, resulting in medicine waste. By rotating the adjusting disc, the connecting column is driven to rotate, which in turn drives the connecting rod and scraper to rotate, scraping the inner wall of the atomizing cup to collect the adhered liquid medicine droplets, thereby improving medicine utilization, avoiding resource waste, and also serving a cleaning function.
[0014] Compared with the prior art, the beneficial effects of the present invention are as follows: The device arranges the connecting pipe on one side of the moving column, and the moving column is squeezed by multiple guide grooves to realize the limiting and fixing of the connecting pipe. The heating frame is equipped with heating elements and water. The water bath environment is formed by heating the water to preheat the connecting pipe, so that the airflow temperature is suitable, avoiding cold mist irritating the airway, reducing discomfort symptoms such as cough and bronchospasm, and improving the use tolerance of children, the elderly, COPD and asthma patients. The staggered arrangement of multiple moving columns can extend the travel and heating area of the connecting pipe in the heating frame, further ensuring the gas preheating effect.
[0015] Furthermore, the gas produced by nebulization is mostly transparent, existing only as a mist within the nebulizing mechanism, making it difficult to visually determine whether the airflow within the connecting tube and the nebulizer cup is normal, and thus impossible to accurately confirm the device's operating status. Therefore, a rotating shaft, driven fan blades, and active fan blades are installed at the top of the nebulizer cup. When the airflow flows, it drives the active fan blades to rotate, which in turn drives the driven fan blades, enabling a direct assessment of the device's operating status and ensuring drug delivery stability and quality.
[0016] After atomization, a large amount of liquid medicine droplets tend to adhere to the inner wall of the atomizing cup, resulting in medicine waste. By rotating the adjusting disc, the connecting column is driven to rotate, which in turn drives the connecting rod and scraper to rotate, scraping the inner wall of the atomizing cup to collect the adhered liquid medicine droplets, thereby improving medicine utilization, avoiding resource waste, and also serving a cleaning function. Attached Figure Description
[0017] Figure 1 is a schematic diagram of the overall structure of a targeted nebulized inhalation drug delivery device for acute lung injury; Figure 2 is a schematic diagram of the structure of the preheating mechanism of a targeted nebulized inhalation drug delivery device for acute lung injury; Figure 3 is a schematic diagram of the structure of the nebulization mechanism of a targeted nebulized inhalation drug delivery device for acute lung injury.
[0018] In the diagram: 1-Atomizer, 2-Connecting pipe, 3-Preheating mechanism, 301-Heating frame, 302-Base plate, 303-Guide groove, 304-Spring, 305-Moving column, 306-Limiting plate, 4-Atomizing mechanism, 401-Atomizing cup, 402-Mask, 403-Rotating shaft, 404-Driven fan blade, 405-Active fan blade, 406-Guide cover, 407-Adjusting plate, 408-Connecting column, 409-Connecting rod, 410-Scraper. Detailed Implementation
[0019] Example 1: Referring to Figures 1 and 2, the present invention provides a technical solution: a targeted nebulized inhalation drug delivery device for acute lung injury, comprising a nebulizer 1, a connecting tube 2, a preheating mechanism 3, and a nebulizing mechanism 4; the preheating mechanism 3 is installed above the nebulizer 1, and the connecting tube 2 is provided inside the preheating mechanism 3, one end of the connecting tube 2 is connected to the nebulizer 1, and the other end of the connecting tube 2 is connected to the nebulizing mechanism 4; the preheating mechanism 3 includes a heating frame 301 fixedly connected to the nebulizer 1, a base plate 302 is provided inside the heating frame 301, a plurality of guide grooves 303 are opened inside the base plate 302, and a spring 304 is provided inside each guide groove 303, one end of the spring 304 is fixedly connected to a moving column 305, and the other end of the spring 304 is fixedly connected to the inner wall of the heating frame 301; a limit plate 306 is fixedly connected to the top of each moving column 305; one side of the heating frame 301 is fixedly connected to the connecting tube 2.
[0020] Nebulized inhalation drug delivery devices atomize liquid medication into tiny droplets, which are then inhaled by the patient through the respiratory tract to achieve local or systemic drug delivery. In existing traditional nebulized drug delivery devices, the connecting tubing between the nebulizer and the nebulizer cup is mostly directly exposed to the external environment without any insulation or preheating structure. This results in low-temperature airflow, especially in cold winter conditions. The low ambient temperature further cools the airflow as it passes through the exposed tubing. When this low-temperature aerosol is directly inhaled into the patient's respiratory tract, it can easily cause cold stimulation to the throat, trachea, and bronchi, leading to adverse reactions such as coughing, sneezing, and throat discomfort. In severe cases, it can even induce airway spasm. For individuals with lung damage, chronic obstructive pulmonary disease, asthma, or other respiratory sensitivities, as well as for debilitated patients, the negative effects of this low-temperature stimulation are even more pronounced, not only reducing treatment comfort but also potentially affecting treatment adherence and drug delivery efficacy.
[0021] To address the aforementioned issues, this device optimizes the design of the pipeline preheating and fixing structure. The connecting pipe 2 is positioned on one side of the moving column 305. Multiple guide grooves 303 inside the housing exert a squeezing and guiding effect on the moving column 305, thereby achieving stable positioning and limiting of the connecting pipe 2. This prevents the pipeline from shifting, bending, or becoming blocked during use, ensuring smooth airflow. The heating frame 301 integrates heating elements and contains a suitable amount of water. The heating elements heat the water to create a constant-temperature water bath environment. This water bath heating method uniformly and gently preheats the connecting pipe 2 passing through the heating frame 301, raising the airflow temperature inside the pipe to a suitable range close to human body temperature. When the preheated atomized gas enters the patient's respiratory tract, it can effectively avoid the cold mist irritating the airway mucosa, significantly reduce discomfort symptoms such as cough, airway spasm, and chest tightness, and greatly improve the use tolerance and treatment comfort of children, the elderly, patients with chronic obstructive pulmonary disease, and asthma patients. At the same time, the multiple moving columns 305 are arranged in an interlaced manner, which can force the connecting pipe 2 to form a tortuous and winding path inside the heating frame 301, effectively extending the heating stroke and heat exchange area of the connecting pipe 2 in the heating area, extending the heat exchange time between the airflow and the water bath environment, so that the airflow in the pipe can fully absorb heat and rise in temperature, further improving the preheating uniformity and preheating effect, and ensuring that the output atomized gas temperature is stable and comfortable.
[0022] Example 2: This example is an improvement on Example 1. Please refer to Figure 3. Specifically, the atomizing mechanism 4 includes an atomizing cup 401. One end of the atomizing cup 401 is connected to the connecting pipe 2. A mask 402 is also installed on one side of the atomizing cup 401. A rotating shaft 403 is rotatably connected above the atomizing cup 401. A driven fan blade 404 is fixedly connected to the top of the rotating shaft 403. An active fan blade 405 is fixedly connected to the bottom of the rotating shaft 403. The active fan blade 405 is disposed inside the transverse tube of the atomizing cup 401.
[0023] A guide cover 406 is also provided on the outside of the active fan blade 405, and the guide cover 406 is fixedly connected to the inside of the atomizing cup 401.
[0024] The guide cover 406 is arranged in an arc shape.
[0025] An adjustment plate 407 is provided at the bottom of the atomizing cup 401. A connecting post 408 is fixedly connected to the top of the adjustment plate 407. The outer side of the connecting post 408 is rotatably connected to the atomizing cup 401. A connecting rod 409 is fixedly connected to one side of the connecting post 408. A scraper 410 is fixedly connected to the other end of the connecting rod 409.
[0026] The scraper 410 is spirally arranged, and the outer side of the scraper 410 is fitted to the inner wall of the atomizing cup 401.
[0027] The gas produced by atomization is mostly transparent, only appearing as a mist inside the atomizing mechanism 4. This makes it difficult to visually determine whether the airflow between the connecting pipe 2 and the atomizing cup 401 is normal, and thus cannot accurately confirm the equipment's operating status. Therefore, a rotating shaft 403, a driven fan blade 404, and an active fan blade 405 are installed at the top of the atomizing cup 401. When the airflow flows, it drives the active fan blade 405 to rotate, which in turn drives the driven fan blade 404 to rotate, enabling a direct assessment of the equipment's operating status and ensuring drug delivery stability and quality. The rotating shaft 403... 03. Both the driven fan blade 404 and the active fan blade 405 are made of lightweight plastic, which helps their subsequent rotation. After atomization, a large amount of liquid medicine droplets are easily attached to the inner wall of the atomizing cup 401, causing waste of medicine. By rotating the adjusting plate 407, the connecting column 408 is driven to rotate. The connecting column 408 drives the connecting rod 409 and the scraper 410 to rotate, scraping the inner wall of the atomizing cup 401, so that the attached liquid medicine droplets fall and are collected, improving the utilization rate of medicine, avoiding waste of resources, and also having a cleaning function.
[0028] This article uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only for the purpose of helping to understand the method and core ideas of the present invention. The above descriptions are only preferred embodiments of the present invention. It should be noted that due to the limitations of textual expression, while there are objectively infinite specific structures, those skilled in the art can make several improvements, modifications, or changes without departing from the principles of the present invention, and can also combine the above technical features in an appropriate manner. These improvements, modifications, changes, or combinations, or the direct application of the inventive concept and technical solution to other situations without modification, should all be considered within the scope of protection of the present invention.
Claims
1. A targeted nebulized inhalation drug delivery device for acute lung injury, characterized in that: The device includes an atomizer (1), a connecting pipe (2), a preheating mechanism (3), and an atomizing mechanism (4). The preheating mechanism (3) is installed above the atomizer (1), and the connecting pipe (2) is installed inside the preheating mechanism (3). One end of the connecting pipe (2) is connected to the atomizer (1), and the other end of the connecting pipe (2) is connected to the atomizing mechanism (4). The preheating mechanism (3) includes a heating frame (301) fixedly connected to the atomizer (1), and the heating frame (301) contains a heating element. The base plate (302) has multiple guide grooves (303) inside, and each guide groove (303) is equipped with a spring (304). One end of the spring (304) is fixedly connected to a moving column (305), and the other end of the spring (304) is fixedly connected to the inner wall of the heating frame (301). The top of each moving column (305) is fixedly connected to a limit plate (306). One side of the heating frame (301) is fixedly connected to the connecting pipe (2).
2. The targeted nebulized inhalation drug delivery device for acute lung injury according to claim 1, characterized in that: The atomizing mechanism (4) includes an atomizing cup (401), one end of which is connected to the connecting tube (2), and a mask (402) is also installed on one side of the atomizing cup (401); a rotating shaft (403) is rotatably connected above the atomizing cup (401), a driven fan blade (404) is fixedly connected to the top of the rotating shaft (403), and an active fan blade (405) is fixedly connected to the bottom of the rotating shaft (403). The active fan blade (405) is located inside the transverse tube of the atomizing cup (401).
3. A targeted nebulized inhalation drug delivery device for acute lung injury according to claim 2, characterized in that: The outer side of the active fan blade (405) is also provided with a guide cover (406), and the guide cover (406) is fixedly connected to the inside of the atomizing cup (401).
4. A targeted nebulized inhalation drug delivery device for acute lung injury according to claim 3, characterized in that: The guide cover (406) is arc-shaped.
5. A targeted nebulized inhalation drug delivery device for acute lung injury according to claim 2, characterized in that: An adjustment plate (407) is provided at the bottom of the atomizing cup (401). A connecting post (408) is fixedly connected to the top of the adjustment plate (407). The outer side of the connecting post (408) is rotatably connected to the atomizing cup (401). A connecting rod (409) is fixedly connected to one side of the connecting post (408). A scraper (410) is fixedly connected to the other end of the connecting rod (409).
6. A targeted nebulized inhalation drug delivery device for acute lung injury according to claim 5, characterized in that: The scraper (410) is spirally arranged, and the outer side of the scraper (410) is fitted to the inner wall of the atomizing cup (401).