Traditional Chinese medicine composition for freeing lung, relieving sore throat, tonifying qi, consolidating body resistance, clearing away heat and toxic materials and application of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition for diffusing lung and relieving sore throat, tonifying qi and consolidating body resistance and clearing away heat and toxic materials as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by mass: 1-7 parts of ginseng, 10-20 parts of liquorice and 3-10 parts of platycodon grandiflorum. According to the traditional Chinese medicine composition, ginseng, platycodon grandiflorum and liquorice in specific parts by mass are used as a traditional Chinese medicine compound, medicinal and edible medicinal materials are used as raw materials for scientific formulation, and the traditional Chinese medicine composition can be used for the recovery period of viral (including coronavirus) or other respiratory tract infectious diseases and has the effects of clearing away heat and toxic materials, tonifying qi and consolidating basis, freeing lung and relieving cough, eliminating phlegm and relieving sore-throat and improving the curative effect. The memory is improved; the physical fatigue is relieved. The raw materials used by the traditional Chinese medicine composition are all medicinal and edible traditional Chinese medicines, are high in safety, can be sufficiently taken for a long time without generating adverse effects, can lighten the body and prolong the life after being taken for a long time, and have a good application prospect.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a traditional Chinese medicine composition that promotes lung function, soothes the throat, invigorates qi, strengthens the body, clears heat, and detoxifies, as well as its preparation method and application. Background Technology

[0002] The recovery period for viral (such as COVID-19) or other respiratory infectious diseases refers to the time when a patient has passed the acute infection phase, but their body has not yet fully recovered to its pre-infection state. This phase may last 1-2 weeks or even longer, during which the patient may still experience some physical symptoms such as fatigue, shortness of breath, cough, muscle or joint pain, headache, palpitations, difficulty concentrating, and memory loss.

[0003] Due to the diverse clinical symptoms and complex course of the disease during the recovery period from COVID-19, exploring drugs that promote the recovery of bodily functions during this period has significant scientific and clinical value. Because of the high cost of developing new Western medicines, traditional Chinese medicine (TCM) formulas have been used in recent years for the recovery period from COVID-19. Classical formulas are the essence of TCM, consisting of prescriptions recorded in ancient Chinese medical texts that are effective and possess distinct characteristics and advantages. Currently, classical formulas are still widely used in modern clinical practice due to their long-term clinical application and proven efficacy. For example, Qingfei Paidu Decoction, as a highly effective TCM treatment for COVID-19, is one of the most widely used and frequently employed TCM formulas in clinical treatment.

[0004] Current technologies mostly employ pure traditional Chinese medicine preparations for prevention and treatment. However, due to the bitter taste of traditional Chinese medicine, medication adherence is poor, resulting in unsatisfactory treatment effects. Traditional Chinese medicine formulas that combine medicinal and edible ingredients are an excellent choice for daily health maintenance and auxiliary management of chronic diseases. Their core advantages lie in their high safety, gentle efficacy, and long-term suitability. They can meet dietary needs while regulating the internal organs, strengthening the body, and preventing diseases. With the development of the times, people are paying more and more attention to health maintenance, and a large number of food products that combine medicinal and edible ingredients have emerged. However, there are currently very few traditional Chinese medicine formulas that combine medicinal and edible ingredients specifically for the recovery period of viral diseases (such as novel coronavirus infection) or other respiratory infectious diseases. Summary of the Invention

[0005] To overcome the problems existing in the prior art, one objective of the present invention is to provide a traditional Chinese medicine composition. A second objective of the present invention is to provide an application of the above-mentioned traditional Chinese medicine composition. A third objective of the present invention is to provide another application of the above-mentioned traditional Chinese medicine composition.

[0006] The concept of "medicine and food sharing the same origin" means that traditional Chinese medicine and food originated simultaneously. The *Huainanzi* states that Shennong tasted the flavors of hundreds of herbs and the sweetness and bitterness of springs, enabling the people to know what to avoid and what to seek. At that time, he encountered seventy poisons in a single day. This shows that in Shennong's era, medicine and food were not distinguished; non-toxic substances were acceptable, while toxic substances were avoided. Ginseng, platycodon, and licorice are all tonifying Chinese herbs. Although they share the same origin as food, they must be used according to the patient's condition. Improper dosage may lead to antagonistic effects, loss of efficacy, or even conflicting properties and meridian tropism, resulting in the opposite effect. This invention uses specific proportions of ginseng, platycodon, and licorice as a compound Chinese medicine formula. Each herb has its own properties and meridian tropism; when the dosage is appropriate, their properties and flavors harmonize, achieving a synergistic effect and working together to achieve the desired effect.

[0007] To achieve the above objectives, the technical solution adopted by the present invention is as follows:

[0008] The first aspect of the present invention provides a traditional Chinese medicine composition, which is prepared from the following raw materials in parts by weight: 1-7 parts of ginseng, 10-20 parts of licorice, and 3-10 parts of platycodon.

[0009] In this formula, ginseng is warm in nature and has a sweet and slightly bitter taste. It nourishes the five internal organs, calms the mind, stabilizes the spirit, stops palpitations, eliminates evil influences, brightens the eyes, improves mood and intelligence, and prolonged use can lighten the body and prolong life.

[0010] Licorice: Sweet and neutral in nature, non-toxic. It treats cold and heat imbalances in the five internal organs, strengthens tendons and bones, promotes muscle growth, increases strength, treats wounds, and detoxifies. Long-term use can lighten the body and prolong life.

[0011] Platycodon grandiflorus: bitter, pungent, neutral. It clears the lungs, soothes the throat, eliminates phlegm, and drains pus. Long-term use can lighten the body and prolong life.

[0012] Preferably, it is prepared from the following raw materials in parts by weight: 1-5 parts ginseng, 13-17 parts licorice, and 5-9 parts platycodon.

[0013] More preferably, the ginseng is present in 2-4 parts by weight.

[0014] More preferably, the licorice is present in 14-16 parts by weight.

[0015] More preferably, the amount of the platycodon root is 6-8 parts by weight.

[0016] Preferably, the dosage form of the traditional Chinese medicine composition is tablets, ointments, powders, decoctions, granules, capsules, or pills.

[0017] Preferably, the traditional Chinese medicine composition can be used as a food product, and can be prepared in the form of liquid or solid beverages, special nutritional foods, or other conventional food products using conventional preparation methods in the art.

[0018] Preferably, it also includes medically acceptable excipients.

[0019] Preferably, the excipients include at least one of the following: a slow-release agent, an excipient, a filler, a binder, a wetting agent, a disintegrant, an absorption promoter, an adsorbent carrier, a surfactant, and a lubricant.

[0020] For those skilled in the art, the aforementioned pharmaceutically acceptable uses of excipients are to improve drug stability or to give drugs appropriate dosage forms for easy transport, carrying, storage, or administration, such as surfactants, lubricants, and preservatives. The types of pharmaceutically acceptable excipients, as well as the selection criteria and methods, are well known to those skilled in the art. Through orthogonal experimental design methods, those skilled in the art can select suitable excipients, their proportions, and preparation processes through a limited number of experiments without inventive effort. For pharmaceutically acceptable excipients in traditional Chinese medicine compound preparations, see *Pharmaceutics* (edited by Cui Lide, Beijing: People's Medical Publishing House, 2007) and *Traditional Chinese Medicine Pharmaceutics* (edited by Zhang Zhaowang, Beijing: China Traditional Chinese Medicine Press, 2007), etc. For oral granules of traditional Chinese medicine, commonly used excipients include starch, lactose, microcrystalline silica gel, and microcrystalline cellulose. Their uses and methods of application in formulations are well known to those skilled in the art, and their dosages can be obtained directly through a limited number of experiments without inventive effort.

[0021] Preferably, the preparation method of the traditional Chinese medicine composition includes the following steps: taking all raw materials for water extraction, extracting 1-3 times, concentrating the extract into a thick paste, and then preparing it into a pharmaceutically acceptable dosage form.

[0022] More preferably, the temperature of the water extraction is 90-100°C.

[0023] The second aspect of the present invention provides for any of the following applications of the traditional Chinese medicine composition described in the first aspect: A) Preparation of anti-inflammatory drugs; B) Prepare medicines or foods for clearing the lungs and relieving sore throat; C) Prepare medicines or foods for invigorating qi and strengthening the body's foundation; D) Prepare medicines or foods for clearing heat and detoxifying; E) Prepare drugs for improving memory; F) Prepare food products to help improve memory; G) Prepare drugs for relieving physical fatigue; H) Prepare food products to help relieve physical fatigue.

[0024] "Boosting Qi and Strengthening the Foundation" refers to a traditional Chinese medicine conditioning method that improves physical condition or promotes recovery by replenishing the body's vital energy and consolidating its foundation.

[0025] "Xuanfei Liyan" refers to a traditional Chinese medicine treatment method that disperses external pathogens, unblocks lung qi, and relieves throat discomfort.

[0026] Clearing heat and detoxifying refers to a traditional Chinese medicine treatment method that removes heat toxins from the body and alleviates the accumulation of heat toxins.

[0027] Preferably, the anti-inflammatory drug is a drug for treating acute inflammation.

[0028] The third aspect of this invention provides the use of the traditional Chinese medicine composition described in the first aspect in the preparation of a medicament for treating symptoms during the recovery period of novel coronavirus infection.

[0029] Preferably, the symptoms of recovery from novel coronavirus infection include at least one of fatigue, shortness of breath, cough, muscle pain, joint pain, headache, palpitations, poor concentration, and memory loss.

[0030] The beneficial effects of this invention are: This invention provides a traditional Chinese medicine composition using specific mass proportions of ginseng, platycodon, and licorice as a compound. It is scientifically formulated using medicinal and edible herbs as raw materials and can be used during the recovery period from viral (including coronavirus) or other respiratory infections. It has the effects of clearing heat and detoxifying, tonifying qi and strengthening the body, promoting lung function and relieving cough, eliminating phlegm and soothing the throat, improving cognition and memory, and relieving physical fatigue. The raw materials used in this invention are all medicinal and edible herbs, ensuring high safety. Long-term, sufficient dosage can be taken without adverse effects, and prolonged use can promote health and longevity, showing promising application prospects. Attached Figure Description

[0031] Figure 1 The results of the cotton ball granulation swelling test in rats are shown; (A) shows the weight gain of rats in each group; (B) shows the weight of granulation tissue in rats in each group. Figure 2 The results of the rat paw edema model experiment are as follows: (A) Weight gain of rats in each group; (B) Swelling rate of toes in each group at 1 hour; (C) Swelling rate of toes in each group at 2 hours. Figure 3 The results of the mouse ear swelling inhibition test are shown; (A) the weight gain of rats in each group; (B) the ear swelling rate of rats in each group. Figure 4 The results of the mouse avoidance test include: (A) body weight gain of mice in each group; (B) latency period of mice; and (C) number of electric shocks to mice. Figure 5 The results of the forced swimming experiment are shown; (A) the weight gain of mice in each group; and (B) the EST time.

[0032] All data were analyzed using one-way ANOVA. " indicates P < 0.05, "<0.01, " "<0.001", <0.0001. Detailed Implementation

[0033] The present invention will be further described in detail below through specific embodiments. Unless otherwise specified, the raw materials used in the following embodiments can be obtained from conventional commercial channels or prepared and isolated through simple synthesis; unless otherwise specified, the processes employed are conventional processes in the art.

[0034] Example 1 This embodiment provides a traditional Chinese medicine composition, wherein the effective ingredients are: ginseng 3 parts, licorice 15 parts, and platycodon 7 parts; the specific preparation steps are as follows: (1) Remove impurities from the above-mentioned medicinal materials, wash them, and then put the medicinal materials into a clay pot or decoction pot; (2) Add 10 times the weight of the medicinal materials in pure water and soak them to allow the medicinal materials to fully absorb water and swell, thereby increasing the dissolution rate of the active ingredients; (3) First, heat the liquid rapidly over high heat until it reaches 100°C and boils violently. Then, reduce the heat to low and keep the liquid at a gentle boil at 100°C. Continue to decoct for 1 hour. Immediately filter the liquid with gauze or a filter screen and collect the filtrate. (4) Add warm water equal to 8 times the total weight of the herbs and decoct for 1 hour for the second time, then collect the filtrate. (5) Mix and concentrate the drug solution obtained in steps (3) and (4) to an appropriate volume, and freeze-dry to obtain the corresponding extract powder.

[0035] Comparative Example 1 This comparative example provides a traditional Chinese medicine composition, wherein the effective ingredients are: 15 parts of licorice and 7.5 parts of platycodon.

[0036] The specific preparation steps are the same as in Example 1.

[0037] Comparative Example 2 This comparative example provides a traditional Chinese medicine composition, wherein the effective ingredients are: 5 parts ginseng, 20 parts licorice, 15 parts platycodon, and 4 parts astragalus.

[0038] Characteristic 1: Comparison of the throat-soothing and throat-moistening effects of various traditional Chinese medicine formulas Animal function tests were conducted according to the "Throat-Clearing and Moisturizing" evaluation method in the "Methods for Functional Testing and Evaluation of Health Foods" (2023 Edition): 1. Rat cotton ball granulation test Adult rats were randomly divided into 6 groups, with 6 rats in each group. Low-dose and high-dose (FORMULA RG Lo, FORMULA RGHi) groups were set up (1.26 g / kg and 2.53 g / kg, respectively). A model control group (equivalent volume of purified water) was also set up. A positive control group (antibacterial and anti-inflammatory capsules 1.08 g / kg) was also set up. Ancient formula group 1 (comparative example 1 Chinese medicine composition, 1.26 g / kg) and ancient formula group 2 (comparative example 2 Chinese medicine composition 1.24 g / kg) were administered orally to the rats daily. The rats' body weight was measured every seven days. The administration volume was 1 mL / 100 g, and the administration was continued for 30 days.

[0039] On day 22 of drug administration, all rats were anesthetized with isoflurane by inhalation, their abdomens were shaved, and disinfected with 75% alcohol and iodine. A 1 cm incision was made in the abdomen (near the xiphoid process), and one 25 mg sterile cotton ball (autoclaved) was inserted into each of the forelimb axillaes through the incision. After the surgery, the skin was sutured, and the wound was disinfected with iodine. On the day of modeling, the drug was administered by gavage 1 hour after the operation, while the model control group received an equal volume of purified water.

[0040] On day 30 of the experiment, rats in each experimental group were given the test sample, while the model control group was given the same volume of solvent. After isoflurane inhalation anesthesia and exsanguination, the rats were euthanized. The skin was cut at the original suture site, and the granulation tissue was removed using cotton balls. The tissue was placed in a pre-weighed, clean petri dish and dried in a constant temperature drying oven at 90°C for 1 hour. The net amount of granuloma was then calculated. Statistical analysis showed significant differences between the low- and high-dose FORMULA RG groups, the ancient formula 1 group, the ancient formula 2 group, and the positive control group compared to the model control group. The results are shown in [Figure number missing]. Figure 1 .

[0041] from Figure 1 As can be seen, the rats in each group gained weight normally during the experiment; compared with the model control group, the net amount of granulomas in the low-dose group, high-dose group, ancient formula 1 group, ancient formula 2 group and positive control group of rats was reduced, all of which had anti-inflammatory effects.

[0042] 2. Rat paw edema test Adult rats were randomly divided into 6 groups, with 6 rats in each group. Low-dose and high-dose (FORMULA RG Lo, FORMULA RG Hi) groups were set up (1.26 g / kg and 2.53 g / kg, respectively). A model control group (equivalent volume of purified water) was also set up. A positive control group (antibacterial and anti-inflammatory capsule 1.08 g / kg) was also set up. Ancient formula group 1 (1.26 g / kg) and ancient formula group 2 (1.24 g / kg) were administered orally to the rats daily. The rats' body weight was measured every seven days. The administration volume was 1 mL / 100 g, and the administration was continued for 30 days.

[0043] One hour after the last administration, 40,000 units of 1% dextran were injected subcutaneously into the right hind paw of each rat (0.1 mL / rat). Before modeling, the volume of the right hind paw of each group of rats was measured using a toe volume analyzer, which was taken as the toe volume at 0 hours. After modeling, the volume of the rat's toes was measured at 1, 2, 4, and 6 hours, with three measurements taken at the same site, and the average value was taken. The difference between the toe volume measured at different times and the toe volume before the inflammatory agent was applied was taken as the swelling value, and the toe swelling rate at each time point was calculated (swelling rate (%) = swelling value / toe volume before inflammation × 100%). Statistical analysis showed that, compared with the model control group, the toe swelling rate was significantly lower in the low-dose FORMULA RG group, high-dose group, traditional formula 1 group, traditional formula 2 group, and positive control group at 1 hour and 2 hours after modeling. The results are shown in the table below. Figure 2 .

[0044] from Figure 2 As can be seen, the rats in each group gained weight normally during the experiment; compared with the model control group, the rats in the low-dose FORMULA RG group, high-dose group, ancient formula 1 group, ancient formula 2 group and positive control group had reduced paw swelling rate at 1 hour and 2 hours after modeling, indicating anti-inflammatory effect; Figure 2 (C) The low and high dose groups of FORMULA RG showed better reduction in toe swelling compared to the ancient formula 1 and ancient formula 2 groups, indicating that the specific compound of the present invention has a superior anti-inflammatory effect.

[0045] 3. Xylene-induced mouse ear swelling test Adult mice were randomly divided into 6 groups, with 6 mice in each group. Low-dose and high-dose (FORMULA RG Lo, FORMULA RGHi) groups were set up (1.26 g / kg, 2.53 g / kg). A model control group (equivalent volume of purified water) was also set up. A positive control group (antibacterial and anti-inflammatory capsules 1.08 g / kg) was also set up. The ancient formula group 1 (2.27 g / kg) and the ancient formula group 2 (2.23 g / kg) were administered orally to the mice daily. The weight of the mice was measured every seven days. The administration volume was 0.2 ml / 10 g, and the administration was continued for 30 days.

[0046] One hour after the last administration, 20 μL of xylene was applied to the center of the right auricle of the mouse ear, allowing it to diffuse freely. Thirty minutes after modeling, the mice were anesthetized with isoflurane, blood was collected from the orbital venous plexus, and the ears were removed. Ear flaps were punched at the same location in both ears using a 9 mm diameter punch and weighed. The difference in weight between the two ears was taken as the auricle swelling value, and the auricle swelling rate was calculated. (Auricle swelling rate (%) = auricle swelling value / control ear flap weight × 100%). Statistical analysis showed that the auricle swelling rate of mice in the low- and high-dose FORMULA RG groups, the Ancient Formula 1 group, the Ancient Formula 2 group, and the positive control group was significantly different from that of the model control group. The results are shown in [Figure 1]. Figure 3 .

[0047] from Figure 3 As can be seen, the mice in each group gained weight normally during the experiment. Compared with the model control group, the auricular swelling rate was reduced in the low-dose FORMULA RG group, high-dose FORMULA RG group, ancient formula 1 group, ancient formula 2 group and positive control group, all of which have anti-inflammatory effects. Among them, the high-dose FORMULA RG group showed a more significant reduction in auricular swelling rate compared with ancient formula 1 group and ancient formula 2 group, indicating that the specific compound of the present invention has a better anti-inflammatory effect.

[0048] Characteristic 2: Evaluation of the efficacy of various traditional Chinese medicine formulas in improving memory The extract of the product described in this invention was used to conduct an animal function test (effect on a scopolamine-induced memory impairment model mouse) according to the "Darkness avoidance test" in the "Methods for Functional Testing and Evaluation of Health Foods" (2023 edition): Adult mice were randomly divided into 5 groups of 10 mice each. Low-dose and high-dose groups (FORMULA RG Lo and FORMULA RG Hi) were set up (2.28 g / kg and 4.56 g / kg, respectively). A model control group (equivalent volume of purified water) was also set up. A blank control group and a positive control group (0.10 g / kg of taurine tablets) were also set up. The mice were administered the medication orally by gavage daily, and their weight was measured every seven days. The dosage was 0.2 ml / 10 g, and the administration was continued for 30 days.

[0049] Ten minutes before the dark avoidance test, all mice, except the blank control group, were intraperitoneally injected with 5 mg / kg scopolamine hydrobromide solution at a dose of 0.1 ml / 10 g. Training began the day after the last administration. Ten minutes before the dark avoidance test, all mice, except the blank control group, were intraperitoneally injected with 5 mg / kg scopolamine hydrobromide solution at a dose of 0.1 ml / 10 g. The latency period from entering the bright room to entering the dark room and receiving an electric shock was measured and recorded for each mouse. Training lasted 5 minutes, and the number of electric shocks within 5 minutes was recorded. The test was repeated 24 hours later, and the latency period for each animal entering the dark room and the number of electric shocks within 5 minutes were recorded. After 5 days of cessation of training, another dark avoidance test was conducted. Statistical analysis showed that, compared with the blank control group, the number of electric shocks in the model control group mice was significantly higher during the first training experiment, with a statistically significant difference (P<0.01), indicating that the learning and memory impairment model of the model mice was established. Compared with the model control group, the number of electric shocks in the high-dose group mice was significantly lower during the first training, with a statistically significant difference (P<0.05). Compared with the model control group, except for the low-dose group, the electric shock latency of all treatment groups was longer than that of the model control group. The results are shown in the table below. Figure 4 .

[0050] from Figure 4As can be seen, the mice in each group gained weight normally during the experiment; in the first training test, compared with the model control group, the number of electric shocks in the high-dose group mice was reduced during the first training (P<0.05), which has an effect on improving memory.

[0051] Characteristic 3: Evaluation of the efficacy of various traditional Chinese medicine formulas in relieving physical fatigue The product extract described in this invention was used to conduct a forced swimming (FST) animal function test, referring to the "Relief of Physical Fatigue" evaluation method in the "Methods for Functional Testing and Evaluation of Health Foods" (2023 Edition) and other relevant literature. Adult mice were randomly divided into 5 groups of 6 mice each. Low-dose and high-dose (FORMULA RG Lo, FORMULA RG Hi) groups (1.14 g / kg, 2.28 g / kg) were set up. A model control group (equivalent volume of purified water) was also set up. A blank control group and a positive control group (VC 75 mg / kg) were also set up. The mice were administered the drug orally by gavage daily, and their weight was measured every three days. The drug volume was 0.1 ml / 10 g. The mice were allowed to swim acclimatize for three days (without drug administration). After 15 days of continuous gavage, various indicators of the function of relieving physical fatigue were tested.

[0052] Ten minutes after the last administration, all mice, except the blank control group, swam until they sank into the water and failed to surface for air within 10 seconds; the exhaustion swimming time (EST) was recorded. Statistical analysis showed that the EST duration was significantly different between the low-dose and high-dose groups and the model control group (P<0.0001). The results are shown in [see attached table]. Figure 5 .

[0053] from Figure 5 As can be seen, the mice in each group gained weight normally during the experiment; compared with the model control group, the mice in the low-dose group and the high-dose group had a longer EST duration and had the effect of relieving physical fatigue.

[0054] Based on the "Expert Consensus on Integrated Traditional Chinese and Western Medicine Rehabilitation Program for Convalescent Patients with Novel Coronavirus Infection" and the "Expert Consensus on Traditional Chinese Medicine Treatment of Common Symptoms After Nucleic Acid / Antigen Negative Conversion in Novel Coronavirus Infection," both expert consensuses mention that symptoms such as cough and sore throat, shortness of breath and fatigue, joint pain, soreness of the waist and knees, body aches and palpitations, anxiety and insomnia, memory loss and poor concentration may occur during the recovery period after infection with the novel coronavirus. These symptoms correspond to the "heat-clearing and detoxifying," "relieving physical fatigue," and "improving memory" effects of this invention. Therefore, the traditional Chinese medicine composition of this invention has great application potential in the preparation of drugs for treating symptoms during the recovery period of novel coronavirus infection.

[0055] The above embodiments are preferred embodiments of the present invention, but the embodiments of the present invention are not limited to the above embodiments. Any changes, modifications, substitutions, combinations, or simplifications made without departing from the spirit and principle of the present invention shall be considered equivalent substitutions and shall be included within the protection scope of the present invention.

Claims

1. A traditional Chinese medicine composition, characterized in that, It is prepared from the following raw materials in parts by weight: ginseng 1-7 parts, licorice 10-20 parts, and platycodon 3-10 parts.

2. The traditional Chinese medicine composition according to claim 1, characterized in that, It is prepared from the following raw materials in parts by weight: ginseng 1-5 parts, licorice 13-17 parts, and platycodon 5-9 parts.

3. The traditional Chinese medicine composition according to claim 1, characterized in that, The dosage form of the traditional Chinese medicine composition is tablets, ointments, powders, decoctions, granules, capsules, or pills.

4. The traditional Chinese medicine composition according to claim 1, characterized in that, It also includes medically acceptable excipients.

5. The traditional Chinese medicine composition according to claim 4, characterized in that, The excipients include at least one of the following: sustained-release agent, excipient, filler, binder, wetting agent, disintegrant, absorption promoter, adsorbent carrier, surfactant, and lubricant.

6. The traditional Chinese medicine composition according to claim 1, characterized in that, The preparation method of the traditional Chinese medicine composition includes the following steps: taking all raw materials for water extraction, extracting 1-3 times, concentrating the extract into a thick paste, and then preparing it into a pharmaceutically acceptable dosage form.

7. The traditional Chinese medicine composition according to claim 6, characterized in that, The water extraction temperature is 90-100℃.

8. The traditional Chinese medicine composition according to any one of claims 1-7 is used in any of the following applications: A) Preparation of anti-inflammatory drugs; B) Prepare medicines or foods for clearing the lungs and relieving sore throat; C) Prepare medicines or foods for invigorating qi and strengthening the body's foundation; D) Prepare medicines or foods for clearing heat and detoxifying; E) Prepare drugs for improving memory; F) Prepare food products to help improve memory; G) Prepare drugs for relieving physical fatigue; H) Prepare food products to help relieve physical fatigue.

9. The use of the traditional Chinese medicine composition according to any one of claims 1-7 in the preparation of a medicament for treating symptoms during the recovery period of novel coronavirus infection.

10. The application according to claim 9, characterized in that, Symptoms during the recovery period from novel coronavirus infection include at least one of the following: fatigue, shortness of breath, cough, muscle pain, joint pain, headache, palpitations, poor concentration, and memory loss.

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