A sugar-based supramolecular emulsifier, its preparation method and application

Abstract

This invention discloses a sugar-based supramolecular emulsifier, its preparation method, and its applications, belonging to the field of supramolecular emulsifier preparation technology. The invention involves reacting sugars, fatty acids, sodium fatty acids, alcohols, and solvents in a mass ratio of 0.8-45:5-15:0-5:35-94.2:120 at 40-95℃ for 5-13 hours to obtain a suspension. The suspension is then dried to obtain a sugar-based supramolecular emulsifier powder. The sugar-based supramolecular emulsifier powder prepared by this invention exhibits excellent emulsification stability and environmental friendliness. Furthermore, the synthesis process is simple and cost-controllable, making it suitable for use in cosmetics, food, pharmaceuticals, and other fields.

Description

Technical Field

[0001] This invention relates to a sugar-based supramolecular emulsifier, its preparation method, and its application, belonging to the field of supramolecular emulsifier preparation technology. Background Technology

[0002] Emulsifiers, as functional additives that significantly reduce interfacial tension and enable immiscible oil and water phases to form stable dispersion systems, are widely used in food, cosmetics, pharmaceuticals, and other fields. Their performance directly determines the stability, texture, safety, and application effects of products. While traditional small-molecule synthetic emulsifiers (such as Tween and Span) can rapidly adsorb at the oil-water interface and significantly reduce interfacial tension, they have drawbacks such as limited intake, potential cumulative toxicity, and unfriendly labeling. Protein-based emulsifiers are easily affected by temperature, ionic strength, and pH fluctuations, leading to denaturation, flocculation, or hydrolytic inactivation. With "clean labeling" and "plant-based" becoming mainstream consumer trends, developing novel emulsifiers that are renewable in origin, metabolically safe, functionally controllable, and can be labeled as "dietary fiber" or "polysaccharides" has become a common demand in the food, personal care, and pharmaceutical industries.

[0003] Sugars, as abundant and renewable natural raw materials, possess unique advantages such as wide availability, good biocompatibility, non-toxicity, non-irritation, and easy biodegradability. Sugar-based emulsifiers (glycosyl emulsifiers) are gradually replacing traditional synthetic emulsifiers and have become a key research focus. Currently commercially available glycosyl emulsifiers include sucrose esters, alkyl polysaccharides, and trehalose derivatives, showing promising application prospects in food preservation, cosmetic conditioning, and other scenarios.

[0004] However, existing glycobased emulsifiers still have many technical limitations. From a structural and performance perspective, traditional glycobased emulsifiers are mostly small-molecule single components with simple molecular structures and limited interfacial adsorption capacity. The resulting emulsion systems are prone to stratification and demulsification under complex conditions such as high temperature, acid-base changes, and long-term storage, making it difficult to meet the stability requirements of high-end products. In cosmetic emulsions, their emulsified particle size is relatively large, affecting the fineness of the product texture and its absorption by the skin.

[0005] The development of supramolecular chemistry has provided a new direction for solving the performance bottlenecks of traditional emulsifiers. Supramolecular emulsifiers achieve molecular self-assembly based on non-covalent bonds (hydrogen bonds, hydrophobic interactions, van der Waals forces, etc.) to form aggregates with specific spatial structures. By controlling the structure of the assembled particles, the interfacial adsorption performance and steric stabilization effect can be optimized, significantly improving the stability of the emulsion.

[0006] Currently, research on constructing glycosyl supramolecular emulsifiers from carbohydrates through supramolecular self-assembly is still in its early stages and has significant shortcomings.

[0007] In summary, current glycosyl emulsifiers suffer from problems such as limited structural performance, complex synthesis processes, and high industrialization difficulty. The development of supramolecular emulsifiers faces bottlenecks including insufficient component compatibility, poor preparation controllability, and weak functional specificity. Therefore, developing a glycosyl supramolecular emulsifier that uses sugars as the core raw material, is prepared through controllable supramolecular self-assembly, possesses excellent emulsifying stability and environmental friendliness, and has a simple, cost-effective synthesis process suitable for multiple applications has become a pressing technical problem to be solved in this field. Summary of the Invention

[0008] To address the aforementioned problems, this invention provides a sugar-based supramolecular emulsifier, its preparation method, and its applications. Specifically, this invention involves reacting sugars, fatty acids, sodium fatty acids, alcohols, and solvents at a mass ratio of 0.8-45:5-15:0-5:35-94.2:120 at 40-95°C for 5-13 hours to obtain a suspension. The suspension is then dried to obtain a sugar-based supramolecular emulsifier powder. The sugar-based supramolecular emulsifier powder prepared by this invention exhibits excellent emulsification stability and environmental friendliness. Furthermore, the synthesis process is simple and cost-controllable, making it suitable for use in cosmetics, food, pharmaceuticals, and other fields.

[0009] The first objective of this invention is to provide a method for preparing a carbohydrate supramolecular emulsifier, comprising the following steps: Sugars, fatty acids, sodium fatty acids, alcohols, and solvents are reacted at 40-95℃ for 5-13 hours in a mass ratio of 0.8-45:5-15:0-5:35-94.2:120 to obtain a suspension. The suspension is then dried to obtain a sugar supramolecular emulsifier powder.

[0010] Optionally, the sugars are one or more of the following: trehalose, erythritol, aloe polysaccharide, tremella polysaccharide, chondrus crispus extract, hydrolyzed sclerotium gum, cellulose, hydroxyethyl cellulose, carboxymethyl cellulose, dextran, xanthan gum, fructooligosaccharide, gum arabic, starch, dextrin, agarose, cyclodextrin, and hydroxypropyl cyclodextrin; wherein the cyclodextrin is one or more of α-cyclodextrin, β-cyclodextrin, and γ-cyclodextrin.

[0011] Optionally, the fatty acid is one or more of the following: undecenoic acid, linolenic acid, stearic acid, linoleic acid, palmitoleic acid, myristic acid, tall oil acid, oleic acid, hydrogenated coconut oil acid, coconut oil acid, caprylic acid, capric acid, lauric acid, palmitic acid, stearic acid, isostearic acid, butyloctanoic acid, docosahexaenoic acid, eicosapentaenoic acid, and hexanoic acid.

[0012] Optionally, the sodium fatty acid is one or more of sodium stearate, sodium linoleate, sodium palmitate, sodium myristate, sodium oleate, sodium cocoate, sodium laurate, sodium palmitate, and sodium isostearate.

[0013] Optionally, the alcohol is one or more of butyloctanol, decanol, decyltetradecol, arachidonicol, hexyldecol, cetyl alcohol, cetearyl alcohol, polydimethylsiloxane alcohol, myristol, behenol, octyldodecyl alcohol, lanosterol, lanolin alcohol, cocoyl alcohol, isocetyl alcohol, isostearyl alcohol, stearyl alcohol, oleyl alcohol, lauryl alcohol, and palm oil alcohol.

[0014] Optionally, the solvent is water.

[0015] Optionally, the reaction is a stirred reaction, with the stirring speed being 100-1000 rpm.

[0016] Optionally, the drying is spray drying, specifically spray drying at a temperature of 180-220℃ and a pressure of 0.3-0.5MPa for 6-12 hours.

[0017] The second objective of this invention is to prepare a sugar supramolecular emulsifier using the method described herein.

[0018] In one embodiment of the present invention, the particle size range of the sugar supramolecular emulsifier is 300-500 nm.

[0019] A third objective of this invention is the application of the sugar supramolecular emulsifier described herein in the preparation of pharmaceuticals, food, or cosmetics.

[0020] Optionally, cosmetics include ointments, creams, lotions, etc.; sugar supramolecular emulsifier powders can enhance the moisturizing, stability, and antioxidant functions of cosmetics.

[0021] Optionally, the medication may include dressings, creams, etc.

[0022] A fourth objective of this invention is to provide a cosmetic product that utilizes the sugar supramolecular emulsifier described in this invention.

[0023] In one embodiment of the present invention, the cosmetic preparation method is as follows: A sugar-based supramolecular emulsifier is added to the oil phase and mixed evenly, then added to the aqueous phase and homogenized and emulsified to obtain a cosmetic product. Among them, the mass concentration of sugar supramolecular emulsifiers in the entire cosmetic product is 0.3-2%.

[0024] Optionally, preservatives and functional ingredients may be added to the cosmetic preparation method at appropriate times as needed.

[0025] Optionally, cosmetics include lotions, creams, and lotions; different aqueous and oil phases can be selected as needed.

[0026] The fifth objective of this invention is to provide a method for preparing emulsions with storage stability and multifunctionality, which employs the sugar supramolecular emulsifier described in this invention.

[0027] Alternatively, multifunctionality refers to enhancing properties such as moisturizing and anti-oxidation.

[0028] The technical effects of this invention are as follows: (1) The sugar supramolecular emulsifier powder prepared by the present invention has excellent emulsification stability, biocompatibility and environmental friendliness.

[0029] (2) The synthesis process of the present invention is simple, the cost is controllable, and it is applicable to many fields such as cosmetics, food, and pharmaceutical preparation.

[0030] (3) The sugar supramolecular emulsifier powder of the present invention has a particle size of 300-500 nm and an EAI index of 92 nm. 2 The emulsion has an ESI index of over 84% and a cell viability retention rate of over 90%. The prepared emulsion is homogeneous and stable without stratification after one month of storage in a high temperature and high humidity environment and after one month of freeze-thaw cycle. The prepared cosmetic has excellent antioxidant properties and is homogeneous and stable without stratification after one month of storage in a high temperature and high humidity environment and after one month of freeze-thaw cycle. Attached Figure Description

[0031] Figure 1 The infrared spectrum of the sugar supramolecular emulsifier powder prepared in Example 1.

[0032] Figure 2 The figures show the stability test results for Examples 1-4, Example 21, Example 23, Example 24, and Comparative Examples 1 and 2. Detailed Implementation

[0033] The preferred embodiments of the present invention are described below. It should be understood that the embodiments are for better explanation of the present invention and are not intended to limit the present invention.

[0034] Test method: 1. Emulsifying activity and stability (EAI / ESI index) test: Add the emulsifier powder to water to prepare an emulsifier aqueous solution with a mass concentration of 1%; weigh the emulsifier aqueous solution and liquid paraffin at a mass ratio of 1:4, vortex mix for 5 minutes to form an emulsion; take 0.1 mL of the emulsion and dilute it with distilled water to 10 mL (dilution factor N=100).

[0035] After standing for 10 min, using distilled water as a blank, measure the absorbance A0 at 500 nm. Substitute the absorbance into the formula to calculate EAI; EAI(m) 2 / g)={(2×2.303) / [C×(1-φ)×10 4 ]}×A 500 × dilution factor; where φ is 0.2; Transfer the emulsion to centrifuge tubes and let it stand for 4 hours. Take 0.1 mL of the upper layer of emulsion each time, dilute it, and measure the absorbance A. t ; Calculate ESI using the formula:

[0036] The emulsion was subjected to accelerated aging tests under two conditions: a high temperature and high humidity (40℃ / 75% RH) constant temperature and humidity chamber and a freeze-thaw cycle (alternating between -20℃ and 25℃, with one cycle completed every 24 hours). After one month, the emulsion was observed to determine whether it was uniform and stable and whether it separated into layers.

[0037] 2. Antioxidant performance test: The in vitro antioxidant capacity was measured using Vitamin C as a positive control. Take 1 mL of the emulsion from Example 18 and Comparative Example 12 and mix it with 5 mL of 25 mg / mL DPPH ethanol solution. React in a water bath at 37°C for 20 min. Measure the absorbance at 517 nm. Record the reading as A after the value stabilizes. x The absorbance of the solvent was measured using the same method and denoted as A0. The DPPH scavenging rate of Example 18 and Comparative Example 12 can then be calculated.

[0038] DPPH clearance rate = (1 - A) x / A0)×100 3. Cell compatibility test: The MTT (3-(4,5-dimethylthiazolyl-2-yl)-2,5-diphenyltetrazolium bromide) method is a classic cell proliferation / toxicity assay that indirectly reflects cell number and viability by detecting the ability of mitochondrial dehydrogenases in living cells to reduce MTT to formazan.

[0039] Take fibroblasts in the logarithmic growth phase and adjust the density (1×10⁻⁶). 4 (cells / well, 96-well plate); add 100 μL of complete culture medium to each well and incubate for 24 h to allow the cells to adhere; Experimental Groups: Blank control group (culture medium only, no cells); Negative control group (untreated cells); Experimental group (0.5% emulsifier aqueous solution); Positive control group (10% PDGF stimulation); Add 10 μL of MTT solution (5 mg / mL, prepared in PBS) to each well (final concentration 0.5 mg / mL); incubate at 37 °C for 4 h, then discard the supernatant; add 150 μL of DMSO to each well and shake slowly for 10 min to dissolve the crystals; measure the absorbance at 490 nm using a microplate reader.

[0040] The formula for calculating cell viability retention rate is as follows: Cell viability (%) = (OD value of experimental group - OD value of blank group) / (OD value of control group - OD value of blank group) × 100% Raw materials used in the examples: Trehalose: BR, 98%; Erythritol: 98%, Shanghai Yuanye Biotechnology Co., Ltd. Tremella polysaccharide: UV ≥ 90%; Chondrus crispus extract: 98%; Hydrolyzed sclerotium gum: molecular weight 500 kDa; Dextran: 99%; Molecular weight 6000 Da; Xanthan gum: 99%; Fructooligosaccharides: 99%; Gum arabic: 99%; Aloe polysaccharides; BR, 60%; Dextrin: Resistant dextrin, food grade, 99%; Agarose: Gel strength (1% gel) > 1200g / cm³ 2 ; α-Cyclodextrin: 99.8%; Docosahexaenoic acid: Purity ≥ 98%; Sodium lauryl var.: 97%; Polydimethylsiloxane alcohol: 99%; Palmitoleic acid: 99%; Sodium palmitate: 99%; Cetearyl alcohol: 99%; Cocolate acid: 99%; Sodium cocoate: 99%; Coconut oil alcohol: 99%; Eicosapentaenoic acid: 98%; Sodium myristate: 98%; Palm oil alcohol: 98%; Sodium palmitate: 99%; Undecenoic acid: 99%; Hydroxyethyl cellulose: 5500-6500 MPa; Linoleic acid: purity ≥ 99%; Hexanoic acid: 99%.

[0041] Example 1 A method for preparing a carbohydrate supramolecular emulsifier includes the following steps: Trehalose, docosahexaenoic acid, sodium lauryl laurate, cocoyl alcohol, and water were reacted at 70°C and 300 rpm for 8 hours in a mass ratio of 30:10:3:60:120 to obtain a suspension. The suspension was then spray-dried (at 190°C and 0.45 MPa for 7 hours) to obtain a sugar supramolecular emulsifier powder.

[0042] Figure 1 Infrared spectrum of the sugar supramolecular emulsifier powder prepared in Example 1. Figure 1 It can be seen that: in the emulsifier, trehalose is present at 1603 cm⁻¹ -1 The peak at 1553 cm⁻¹ shifts to lower wavenumbers (1553 cm⁻¹). -1 The shift in absorption peak at 3402 cm⁻¹ originates from the change in electron cloud density after supramolecular interactions. Simultaneously, the emulsifier exhibits this shift. -1 There is a distinct hydrogen bond absorption peak at this point, compared to 3260 cm⁻¹ for trehalose. -1 A clear shift towards higher wavenumbers was observed, and these data confirm the formation of supramolecular systems.

[0043] Example 2 A method for preparing a carbohydrate supramolecular emulsifier includes the following steps: Erythritol, palmitoleic acid, sodium palmitate, cetearyl alcohol, and water were reacted at 75°C and 400 rpm for 6 hours in a mass ratio of 45:15:5:94:120 to obtain a suspension. The suspension was then spray-dried (at 190°C and 0.45 MPa for 7 hours) to obtain a sugar supramolecular emulsifier powder.

[0044] Example 3 A method for preparing a carbohydrate supramolecular emulsifier includes the following steps: Tremella polysaccharide, cocoacid, sodium cocoate, cocoyl alcohol, and water were reacted at 50℃ and 500rpm for 10h in a mass ratio of 0.8:5:1:35:120 to obtain a suspension. The suspension was then spray-dried (at 190℃ and 0.45MPa for 7h) to obtain a sugar supramolecular emulsifier powder.

[0045] Example 4 A method for preparing a carbohydrate supramolecular emulsifier includes the following steps: Trehalose, eicosapentaenoic acid, sodium myristate, palmitole alcohol, and water were reacted at 80°C and 500 rpm for 12 h in a mass ratio of 25:15:4:56:120 to obtain a suspension. The suspension was then spray-dried (at 190°C and 0.45 MPa for 7 h) to obtain a sugar supramolecular emulsifier powder.

[0046] Example 5 A method for preparing a carbohydrate supramolecular emulsifier includes the following steps: α-Cyclodextrin, cocoacid, sodium palmitate, cetearyl alcohol, and water were reacted at 50°C and 600 rpm for 9 h in a mass ratio of 40:10:5:75:120 to obtain a suspension. The suspension was then spray-dried (at 190°C and 0.45 MPa for 7 h) to obtain a sugar supramolecular emulsifier powder.

[0047] Example 6 In Example 1, docosahexaenoic acid was replaced with undecenoic acid and sodium laurate was replaced with sodium linoleate, while other aspects remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0048] Example 7 In Example 1, trehalose was replaced with hydroxyethyl cellulose, docosahexaenoic acid with linoleic acid, and sodium laurate with sodium isostearate, while other components remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0049] Example 8 In Example 1, docosahexaenoic acid was replaced with hexanoic acid and sodium laurate was replaced with sodium stearate, while other aspects remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0050] Example 9 The mass ratio of trehalose, docosahexaenoic acid, sodium lauryl laurate, cocoyl alcohol, and water in Example 1 was adjusted to 30:15:4:76:120, while other aspects remained the same as in Example 1, to obtain a sugar supramolecular emulsifier powder.

[0051] Example 10 The mass ratio of trehalose, docosahexaenoic acid, sodium lauryl laurate, cocoyl alcohol, and water in Example 1 was adjusted to 45:5:0:80:120, while other aspects remained the same as in Example 1, to obtain a sugar supramolecular emulsifier powder.

[0052] Example 12 The trehalose in Example 1 was replaced with Carrageenan extract; everything else remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0053] Example 13 The trehalose in Example 1 was replaced with hydrolyzed sclerotium gum; everything else remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0054] Example 14 The trehalose in Example 1 was replaced with dextran; everything else remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0055] Example 15 The trehalose in Example 1 was replaced with xanthan gum; everything else remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0056] Example 16 The trehalose in Example 1 was replaced with fructooligosaccharide; everything else remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0057] Example 17 The trehalose in Example 1 was replaced with gum arabic; everything else remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0058] Example 18 The trehalose in Example 1 was replaced with aloe polysaccharide; everything else remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0059] Example 19 The trehalose in Example 1 was replaced with dextrin (resistant dextrin); everything else remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0060] Example 20 The trehalose in Example 1 was replaced with agarose; everything else remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0061] The obtained emulsifier was subjected to performance testing, and the test results are as follows: Table 1

[0062] Comparative Example 1 In Example 1, docosahexaenoic acid was replaced with glycolic acid, while other aspects remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0063] The results showed that no homogeneous powder was formed, and the EAI index was 34.6m. 2 / g, ESI is 21.4%, the prepared emulsion is unstable under high temperature and high humidity conditions for 1 month and exhibits stratification.

[0064] Comparative Example 2 The sodium lauryl ester in Example 1 was replaced with sodium tallooleate, while other aspects remained the same as in Example 1, to obtain a sugar supramolecular emulsifier powder.

[0065] The results showed that a gel-like mass was formed, with an EAI index of 44.6m. 2 The emulsion prepared with a concentration of / g and an ESI of 30.4% was unstable and thickened after being frozen for one month.

[0066] Comparative Example 3 In Example 1, coconut oil alcohol was replaced with n-octanol, while other aspects remained the same as in Example 1, resulting in a sugar supramolecular emulsifier powder.

[0067] The results showed that when the powder particle size was approximately 1500 nm, the resulting emulsion rapidly separated into layers.

[0068] Comparative Example 4 The coconut oil alcohol in Example 1 was omitted, while everything else remained the same as in Example 1, to obtain a sugar supramolecular emulsifier powder.

[0069] The results showed that no homogeneous powder was formed, and the EAI index was 40.8m. 2 / g, ESI 23.4%, the prepared emulsion is unstable under freezing conditions for 1 month and exhibits stratification.

[0070] Comparative Example 5 The mass ratio of trehalose, docosahexaenoic acid, sodium lauryl laurate, cocoyl alcohol, and water in Example 1 was adjusted to 30:0:3:60:120, while other aspects remained the same as in Example 1, to obtain a sugar supramolecular emulsifier powder.

[0071] The results showed that a homogeneous powder was not formed, cell viability was less than 50%, and the prepared emulsion was unstable under high temperature and high humidity conditions for one month, exhibiting thickening and stratification.

[0072] Comparative Example 6 The mass ratio of trehalose, docosahexaenoic acid, sodium lauryl laurate, cocoyl alcohol, and water in Example 1 was adjusted to 30:10:3:20:120, while other aspects remained the same as in Example 1, to obtain a sugar supramolecular emulsifier powder.

[0073] The results showed that the powder particle size was approximately 2000 nm and the EAI index was 51.6 nm. 2 / g, ESI 34.4%, the prepared emulsion is unstable under high temperature and high humidity conditions for 1 month, and thickening and stratification phenomenon occurs.

[0074] Comparative Example 7 The mass ratio of trehalose, docosahexaenoic acid, sodium lauryl laurate, cocoyl alcohol, and water in Example 1 was adjusted to 60:10:3:60:120, while other aspects remained the same as in Example 1, to obtain a sugar supramolecular emulsifier powder.

[0075] The results showed that the powder particle size was about 1600 nm, and the emulsion made from it was unstable under freezing conditions for 1 month and exhibited stratification.

[0076] Comparative Example 8 The reaction temperature in Example 1 was adjusted to 30°C, while other aspects remained the same as in Example 1, to obtain a sugar supramolecular emulsifier powder.

[0077] The results showed that no homogeneous powder was formed, the cell activity was retained at approximately 23%, and the prepared emulsion was unstable under high temperature and high humidity conditions for one month, exhibiting oil exudation.

[0078] Comparative Example 9 The reaction temperature in Example 1 was adjusted to 100°C, while other aspects remained the same as in Example 1, to obtain a sugar supramolecular emulsifier powder.

[0079] The results showed that a gel-like mass was formed, with an EAI index of 41.9m. 2 / g, ESI is 27.8%, the prepared emulsion is unstable under high temperature and high humidity conditions for 1 month, and oil phase precipitation occurs.

[0080] Example 21 A method for preparing an emulsion based on the supramolecular emulsifier of Example 1 includes the following steps: Cetyl ethylhexanoate (7506), caprylic / capric triglyceride (GTCC), squalane, and polydimethylsiloxane were added to an oil pan and heated at 85°C and 350 rpm until completely dissolved. The supramolecular emulsifier powder from Example 1 was added, mixed evenly, and kept warm to obtain the oil phase. Glycerin, 980 (carbomer), and water were added to an emulsification pan and heated at 85°C and 600 rpm until completely dissolved to obtain the aqueous phase. The oil phase was added to the aqueous phase, homogenized at 2500 rpm for 5 min, and kept warm at 85°C for 20 min. The temperature was then lowered to 55°C, arginine was added, and stirring and cooling continued. When the temperature reached 40°C, the preservative (PE9010) was added. The emulsion was then cooled to room temperature to obtain the finished product. The emulsion contains, by mass percentage, 4% cetyl ethylhexanoate (7506), 3% caprylic / capric triglyceride (GTCC), 3% squalane, 1% polydimethylsiloxane, 5% glycerol, 0.3% 980 (carbomer), 1% supramolecular emulsifier powder from Example 1, 0.3% arginine, 0.5% preservatives, and the remainder is water.

[0081] The obtained emulsion was subjected to performance testing, and the test results are as follows: Table 2

[0082] Example 22 A method for preparing a cream based on supramolecular emulsifier powder from Example 1 includes the following steps: Cetyl ethylhexanoate (7506), caprylic / capric triglyceride (GTCC), squalane, cetearyl alcohol, and polydimethylsiloxane were added to an oil pan and heated at 85°C and 400 rpm until completely dissolved. The supramolecular emulsifier powder from Example 1 was added, mixed evenly, and kept warm to obtain the oil phase. Glycerin and water were added to an emulsification pan and heated at 85°C and 500 rpm until completely dissolved to obtain the aqueous phase. The oil phase was added to the aqueous phase and homogenized at 3000 rpm for 2 min. Clariant Aristoflex AVC was added, and homogenized at 1200 rpm for 5 min. The mixture was kept at 85°C for 20 min. The temperature was then lowered to 40°C, and a preservative (PE9010) was added. The mixture was allowed to cool to room temperature to obtain the finished cream. The cream contains, by weight percentage, 10% cetyl ethylhexanoate (7506), 7% caprylic / capric triglyceride (GTCC), 4.5% squalane, 1.5% hexadecyl alcohol, 2% polydimethylsiloxane, 3% glycerin, 0.5% Clariant Aristoflex AVC, 1.5% supramolecular emulsifier powder from Example 1, 0.5% preservatives, and the remainder is water.

[0083] The obtained cream was subjected to performance testing, and the test results are as follows: Table 3

[0084] Example 23 A method for preparing a cream based on supramolecular emulsifier powder from Example 1 includes the following steps: Meadowfoam seed oil, caprylic / capric triglyceride (GTCC), squalane, cetearyl alcohol, polydimethylsiloxane, and shea butter were added to an oil pan and heated at 85°C and 400 rpm until completely dissolved. The supramolecular emulsifier powder from Example 1 was added, mixed evenly, and kept warm to obtain the oil phase. Glycerin and water were added to an emulsification pan and heated at 85°C and 500 rpm until completely dissolved to obtain the aqueous phase. The oil phase was added to the aqueous phase and homogenized at 3000 rpm for 2 minutes. Clariant Aristoflex AVC was added, and homogenized at 1200 rpm for 5 minutes. The mixture was kept warm at 85°C for 20 minutes. The temperature was then lowered to 40°C, and a preservative (PE9010) was added. The product cream was obtained after the temperature dropped to room temperature. The cream, by weight percentage, contains 5% meadowfoam seed oil, 8% caprylic / capric triglyceride (GTCC), 3% squalane, 2.5% hexadecyl alcohol, 2% polydimethylsiloxane, 3% shea butter, 3% glycerin, 0.8% Clariant Aristoflex AVC, 2% supramolecular emulsifier powder from Example 1, 0.5% preservatives, and the remainder is water.

[0085] The obtained frost was subjected to performance testing, and the test results are as follows: Table 4

[0086] Comparative Example 10 In Example 21, the supramolecular emulsifier powder was changed to trehalose, while other aspects remained the same as in Example 21, resulting in an emulsion.

[0087] The creams obtained in Example 21 and Comparative Example 10 were subjected to performance tests, and the test results are as follows: Table 5

[0088] Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Anyone skilled in the art can make various modifications and alterations without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention should be determined by the claims.

Claims

1. A method for preparing a carbohydrate supramolecular emulsifier, characterized in that, Includes the following steps: Sugars, fatty acids, sodium fatty acids, alcohols, and solvents are reacted at 40-95℃ for 5-13 hours in a mass ratio of 0.8-45:5-15:0-5:35-94.2:120 to obtain a suspension. The suspension is then dried to obtain a sugar supramolecular emulsifier powder.

2. The method according to claim 1, characterized in that, The sugars are one or more of the following: trehalose, erythritol, aloe polysaccharide, tremella polysaccharide, chondrus crispus extract, hydrolyzed sclerotium gum, cellulose, hydroxyethyl cellulose, carboxymethyl cellulose, dextran, xanthan gum, fructooligosaccharide, gum arabic, starch, dextrin, agarose, cyclodextrin, and hydroxypropyl cyclodextrin.

3. The method according to claim 1, characterized in that, The fatty acids are one or more of the following: undecenoic acid, linolenic acid, stearic acid, linoleic acid, palmitoleic acid, myristic acid, tall oil acid, oleic acid, hydrogenated coconut oil acid, coconut oil acid, caprylic acid, capric acid, lauric acid, palmitic acid, stearic acid, isostearic acid, butyloctanoic acid, docosahexaenoic acid, eicosapentaenoic acid, and hexanoic acid.

4. The method according to claim 1, characterized in that, Sodium fatty acids are one or more of sodium stearate, sodium linoleate, sodium palmitate, sodium myristate, sodium oleate, sodium cocoate, sodium laurate, sodium palmitate, and sodium isostearate.

5. The method according to claim 1, characterized in that, The alcohol is one or more of the following: butyloctanol, decanol, decyltetradecol, arachidonicol, hexyldecol, cetyl alcohol, cetearyl alcohol, polydimethylsiloxane alcohol, myristol, behenol, octyldodecyl alcohol, lanosterol, lanolin alcohol, cocoyl alcohol, isocetol, isostearol, stearol, oleyl alcohol, lauryl alcohol, and palm oil alcohol.

6. The method according to claim 1, characterized in that, The solvent is water; the stirring speed is 100-1000 rpm; spray drying is carried out at a temperature of 180-220℃ and a pressure of 0.3-0.5MPa for 6-12 hours.

7. The sugar supramolecular emulsifier prepared by the method according to any one of claims 1-6.

8. The use of the sugar supramolecular emulsifier according to claim 7 in the preparation of pharmaceuticals, food or cosmetics.

9. A cosmetic product, characterized in that, The sugar supramolecular emulsifier described in claim 7 was used.

10. A method for preparing an emulsion with storage stability and multifunctionality, characterized in that, The sugar supramolecular emulsifier described in claim 7 was used.

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