Fluid delivery system and method for continuous fluid flow

Abstract

A fluid delivery system for continuous fluid flow includes a first inlet in fluid communication with a first pump; a first pressure sensor for detecting a first fluid pressure downstream of the first pump; a second inlet in fluid communication with a second pump; a second pressure sensor for detecting a second fluid pressure downstream of the second pump; an outlet; a valve including a first position and a second position, wherein the first position fluidly connects the first inlet to the outlet, and the second position fluidly connects the first inlet, the second inlet, and the outlet; and a controller system including a processor and a memory.

Description

Background Technology

[0001] Valves, confluencers, and diverters are typically used to control the passage of fluid and can be used to control the flow rate of fluid along one or more fluid paths. Depending on the type of valve used, the position of one or more valve components can be adjusted to achieve the desired delivery of fluid along the fluid path. In many applications, two or more input fluid flows are combined in some way to produce an output fluid flow. It is generally desirable to provide fluid flow to downstream processing through this single output flow. Applications using two or more pumps to drive the input fluid flows often encounter interruptions in the combined output fluid flow and / or pressure fluctuations.

[0002] Typically, pressure pulsations or fluctuations occur when attempting to combine two or more input fluid flows from alternating pumping mechanisms into a single continuous output flow. These pressure pulsations are undesirable because they can reduce the efficiency and accuracy of downstream processing and analysis. For example, analytical techniques such as high-performance liquid chromatography, mass spectrometry, and analytical separation devices are more accurate and efficient when a continuous (uninterrupted) fluid flow is provided without pressure pulsations or fluctuations. Therefore, it is desirable to provide a continuous fluid delivery to these downstream systems at a substantially constant pressure. Summary of the Invention

[0003] According to one aspect, a fluid delivery system for continuous fluid flow includes: a first inlet in fluid communication with a first pump; a first pressure sensor for detecting a first fluid pressure downstream of the first pump; a second inlet in fluid communication with a second pump; a second pressure sensor for detecting a second fluid pressure downstream of the second pump; an outlet; a valve including a first position and a second position, wherein the first position fluidly connects the first inlet to the outlet, and the second position fluidly connects the first inlet, the second inlet, and the outlet; and a controller system including a processor and a memory.

[0004] The controller system described in the preceding paragraph is communicatively connected to a first pump, a second pump, a first pressure sensor, a second pressure sensor, and a valve. The controller system receives signals from the first pressure sensor indicating a first fluid pressure and from the second pressure sensor indicating a second fluid pressure. The processor is programmed to guide the valve from a first position to a second position in response to the first fluid pressure being approximately equal to the second fluid pressure, and substantially simultaneously stop the fluid flow through the first inlet.

[0005] According to another aspect, a method of conveying fluid in a continuous fluid transport system includes: receiving a first fluid through a first inlet in fluid communication with a first pump; receiving one or more signals from a first pressure sensor indicating a first fluid pressure of the first fluid; receiving one or more signals from a second pressure sensor indicating a second fluid pressure downstream of a second pump; comparing the first fluid pressure with the second fluid pressure, and upon determining that the first pressure is approximately equal to the second pressure, (i) operably controlling a valve to switch the valve from a first position to a second position, wherein the first position allows fluid flow of the first fluid through a system outlet, and the second position is fluidly connected to the first pump, the second pump, and the system outlet; and (ii) stopping fluid flow through the first inlet substantially simultaneously with switching the valve from the first position to the second position.

[0006] According to another aspect, a fluid delivery system for continuous fluid flow includes: a first pump; a first pump pressure sensor for detecting fluid pressure associated with a chamber of the first pump; a second pump; a second pump pressure sensor for detecting fluid pressure associated with a chamber of the second pump; one or more flow reservoirs; a shear valve including a rotor and a stator, the rotor being rotatable about an axis relative to the stator, the rotor including a first rotor slot and the stator including a first stator orifice, a second stator orifice, a third stator orifice, and a fourth stator orifice, wherein the first stator orifice is in fluid communication with the first pump, the second stator orifice is in fluid communication with the second pump, the third stator orifice is in fluid communication with one or more flow reservoirs, and the fourth stator orifice is in fluid communication with an outlet; and a controller system including a processor and a memory, wherein the controller system is communicatively coupled to the first pump, the first pump pressure sensor, the second pump, the second pump pressure sensor, and the shear valve.

[0007] The fluid delivery system described in the preceding paragraph may include a controller system that receives signals indicating a first pressure from a first pump pressure sensor and indicating a second pressure from a second pump pressure sensor, wherein the processor is operable to control a shear valve in response to the first pressure being approximately equal to the second pressure, such that the shear valve rotates the rotor from a first position to a second position fluidly connecting the first rotor slot, the first stator orifice, the second stator orifice, and the outlet, while simultaneously operable to control the first pump, such that the fluid flow from the first pump is stopped substantially simultaneously.

[0008] According to another aspect, a method for controlling a shear valve for fluid transport includes: receiving one or more signals from a first pump pressure sensor indicating a first pressure generated by the first pump; receiving one or more signals from a second pump pressure sensor indicating a second pressure generated by the second pump; comparing the first pressure with the second pressure; and, when determining that the first pressure is approximately equal to the second pressure, operably controlling the shear valve to rotate the rotor from a first position to a second position (the second position fluidly connecting the first rotor slot, the first stator orifice, the second stator orifice, and the outlet) and operably controlling the first pump to stop substantially simultaneously with rotating the rotor to the second position. Attached Figure Description

[0009] This document discloses non-limiting and non-exhaustive illustrative embodiments. Referring to the illustrative embodiments depicted in the accompanying drawings, in which:

[0010] Figure 1 The illustration shows a fluid delivery system 100 for continuous fluid flow according to some embodiments.

[0011] Figure 2 The illustration shows a method 200 for conveying a continuous fluid flow according to some embodiments.

[0012] Figure 3 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments.

[0013] Figure 4 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments.

[0014] Figure 5 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments.

[0015] Figure 6 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments.

[0016] Figure 7 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments.

[0017] Figure 8 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments.

[0018] Figure 9 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments.

[0019] Figure 10 The illustration depicts a method for controlling a shear valve for continuous fluid delivery according to some embodiments. Detailed Implementation

[0020] Embodiments of this disclosure provide novel systems and methods for providing a continuous fluid flow to downstream systems. Many downstream systems require a single inlet for fluid. Typically, switching between two or more fluid sources at a confluence results in discontinuous flow due to pressure pulsations, undesirable flow variations, and differential pressure. Many systems, such as analytical devices, operate more accurately and efficiently when a continuous fluid flow is provided. By controlling valves or confluences based on certain processing conditions, the systems and methods of this disclosure can provide a continuous fluid flow through the system outlet while switching between multiple fluid sources, such as two or more pumps.

[0021] As used herein, “continuous fluid flow” can refer to a substantially uninterrupted flow of one or more fluids. For example, continuous fluid flow can refer to a fluid flow without pressure pulsations, flow noise, flow variations, and / or pressure fluctuations.

[0022] Figure 1 The illustration shows a fluid delivery system 100 for continuous fluid flow according to some embodiments. System 100 includes a system inlet 101, a first pump 102, a first pressure sensor 104, a first conduit 106, a second pump 112, a second pressure sensor 114, a second conduit 116, a valve 120, an output 130, and a controller system 150. Controller system 150 includes a processor 152 and a memory 154. System 100 can be used to provide a continuous fluid flow to downstream processing. In one example, the continuous fluid flow includes a flow without pressure pulsations. Pressure pulsations can include pressure changes greater than 0.1%, greater than 0.5%, greater than 1%, greater than 3%, greater than 5%, or values ​​between these. Alternatively, pressure pulsations can be measured as absolute pressure values. In one example, a pressure pulsation is defined as an increase / decrease in fluid pressure greater than 0.01 bar. In another example, a pressure pulsation is defined as an increase / decrease in fluid pressure greater than 0.1 bar. In yet another example, a pressure pulsation is defined as an increase / decrease in fluid pressure greater than 1 bar.

[0023] In one example, system 100 is sufficient to provide a continuous flow of fluid while switching between two or more pumps and using only a single pump at a time. The operating pressure and flow rate of the fluid in system 100 can depend on the downstream system. System 100 can provide a continuous flow of fluid through outlet 130 without a programmed flow transition from fluid from first pump 102 to fluid from second pump 112. A programmed flow transition can include a shift in the flow contribution from one pump to another. A programmed flow transition can include providing flow from a first fluid source through the outlet while simultaneously providing flow from a second fluid source through the same outlet. Because no programmed flow transition is required, one pump can distribute while another pump draws.

[0024] The first pump 102 may be in fluid communication with one or more of the first pressure sensor 104 and the first conduit 106. The first pump 102 may be filled and fluidly connected to an optional reservoir. In one example, fluid communication includes connecting two or more components to conduits, pipes, orifices, valves, and / or pumps sufficient to allow fluid to flow between the two or more components. In another example, fluid communication includes two or more components (which may be physically connected or not) wherein fluid is capable of flowing between the two or more components. The first pump 102 is capable of pressurizing a fluid, such as a first fluid (not shown), sufficient to allow fluid delivery through outlet 130. In one example, the first pump 102 includes a pump sufficient for solvent delivery. In another example, the first pump 102 is a positive displacement pump, such as a reciprocating pump, a syringe pump, and a piston pump. The first pump 102 may include a syringe pump comprising a pump chamber and a piston / plunger. The syringe pump may further include a guide rod, a motor, and a lead screw.

[0025] The first pressure sensor 104 may be downstream of the first pump 102 and may be in fluid communication with one or more of the first pump 102 and the first conduit 106. The first pressure sensor 104 is capable of transmitting a signal indicating the pressure of a first fluid. Therefore, the first pressure sensor 104 is capable of transmitting a signal indicating the outlet pressure of the first pump 102. The first pressure sensor 104 may measure absolute pressure, differential pressure, and gauge pressure. In one example, the first pressure sensor 104 is sufficient to measure the pressure of one or more liquids. In another example, the first pressure sensor 104 may include all sensors, transducers, and elements capable of generating an electrical signal proportional to pressure or pressure changes. In yet another example, the first pressure sensor 104 includes one or more of a strain gauge pressure sensor, a piezoelectric pressure sensor, and a capacitive pressure sensor.

[0026] The second pump 112 may be in fluid communication with one or more of the second pressure sensor 114 and the second conduit 116. The second pump 112 may be filled and fluidly connected to an optional reservoir. This optional reservoir may be the same reservoir used for the first pump 102. The second pump 112 is capable of pressurizing a fluid, such as a second fluid (not shown), sufficiently to allow fluid delivery through outlet 130. The first and second fluids may be the same fluid (with the same composition) or different fluids. Therefore, the first and second fluids may have the same liquid composition. In one example, the second pump 112 includes a pump sufficient for solvent delivery. In another example, the second pump 112 is a positive displacement pump, such as a reciprocating pump, a syringe pump, and a piston pump. The second pump 112 may include a syringe pump comprising a pump chamber and a piston / plunger. The syringe pump may further include a guide rod, a motor, and a lead screw.

[0027] The second pressure sensor 114 may be downstream of the second pump 112 and may be in fluid communication with one or more of the second pump 112 and the second conduit 116. The second pressure sensor 114 is capable of transmitting a signal indicating the pressure of a second fluid. Therefore, the second pressure sensor 114 is capable of transmitting a signal indicating the outlet pressure of the second pump 112. The second pressure sensor 114 may measure absolute pressure, differential pressure, and gauge pressure. In one example, the second pressure sensor 114 is sufficient to measure the pressure of one or more liquids. In another example, the second pressure sensor 114 may include all sensors, transducers, and elements capable of generating an electrical signal proportional to pressure or pressure changes. In yet another example, the second pressure sensor 114 includes one or more of a strain gauge pressure sensor, a piezoelectric pressure sensor, and a capacitive pressure sensor.

[0028] Valve 120 may be in fluid communication with one or more of the following: system inlet 101, first pump 102, first pressure sensor 104, first line 106, second pump 112, second pressure sensor 114, second line 116, and outlet 130. In one example, first line 106, second line 116, and outlet 130 are components of valve 120. Valve 120 may include a first position and a second position. The first position fluidly connects first line 106 to outlet 130. The second position fluidly connects first line 106, second line 116, and outlet 130. Valve 120 may further include a third position fluidly connecting second line 116 to outlet 130.

[0029] Valve 120 may include a valve actuator for moving, rotating, or switching one or more components within valve 120. For example, the valve actuator may be used to switch the position of the valve from a first position to a second position or from a second position to a first position. One or more of the first pump 102 and the second pump 112 may be upstream of valve 120. One or more of the first pressure sensor 104 and the second pressure sensor 114 may be upstream of valve 120.

[0030] Outlet 130 may be in fluid communication with valve 120. Outlet 130 may deliver fluid pumped by one or more of the first pump 102 and the second pump 112 to a downstream process. Outlet 130 may be part of valve 120 and / or may be a line or conduit for delivering liquid. Outlet 130 may include a flow restrictor that establishes a back pressure as a threshold for outlet flow. In one example, a pressure of at least 5 bar, at least 6 bar, at least 8 bar, or at least 10 bar is applied to outlet 130. System 100 may be used to provide a continuous flow of fluid to downstream devices and processes. In one example, outlet 130 delivers fluid to downstream processes such as reaction chambers, separation devices, downstream pumps, tanks, and / or valves, chromatographic devices, and / or spectroscopic devices. In another example, outlet 130 delivers fluid to downstream processes such as high-performance liquid chromatography (HPLC) units and mass spectrometry (MS) units. In yet another example, outlet 130 delivers fluid to a mass spectrometer nebulizer.

[0031] The controller system 150 includes a processor 152 and a memory 154. The processor 152 is communicatively coupled to the memory 154. The memory 154 may include non-transient memory. The controller system 150 is communicatively coupled to one or more of the first pump 102, the first pressure sensor 104, the second pump 112, the second pressure sensor 114, and the valve 120. Therefore, the processor 152 is capable of operatively controlling one or more of the first pump 102, the second pump 112, and the valve 120. The controller system 150 can receive a signal indicating a first fluid pressure from the first pressure sensor 104, and the controller system 150 can receive a signal indicating a second fluid pressure from the second pressure sensor 114.

[0032] In response to a first fluid pressure approximately equal to a second fluid pressure, processor 152 is operable to control (and / or direct) valve 120 sufficiently to switch / move valve 120 from a first position to a second position or from a third position to a second position. In one example, when valve 120 moves from the first position to the second position, processor 152 is operable to stop fluid flow through the first conduit 106 substantially simultaneously. Stopping fluid flow through the first conduit 106 may include operable to control the first pump 102 to stop. Similarly, when valve 120 moves to the second position, processor 152 is operable to stop fluid flow through the second conduit 116 substantially simultaneously.

[0033] Additionally, in response to a signal from a valve position sensor adapted to detect the valve position, processor 152 can operatively control valve 120. Processor 152 can determine whether a first fluid pressure is approximately equal to a second fluid pressure based on stored differential pressure conditions. For example, processor 152 can compare the pressure difference between the first and second fluid pressures (such as a percentage differential or an absolute differential) with stored differential pressure conditions to determine whether the pressures are approximately equal. In one example, if the pressure difference between the first and second fluid pressures is a value included in stored differential pressure conditions, processor 152 determines that the pressures are approximately equal.

[0034] In some embodiments, the stored differential pressure condition can be a percentage value of the pressure difference between a first fluid pressure and a second fluid pressure. In one example, the stored differential pressure condition includes a percentage value between 0.01% and 10%. In another example, the stored differential pressure condition includes a percentage value between about 0.1% and about 5%. In yet another example, the stored differential pressure condition includes a percentage value between about 0.5% and about 2%. The stored differential pressure condition can include percentage values ​​less than 5%, less than 4%, less than 3%, less than 2%, or less than 1%.

[0035] In other embodiments, the stored differential pressure condition may include a range of values. In one example, the stored differential pressure condition includes values ​​between -0.2 bar and +0.2 bar. In another example, the stored differential pressure condition includes values ​​between -0.1 bar and +0.1 bar. In yet another example, the stored differential pressure condition includes values ​​between -0.05 bar and +0.05 bar. For example, the stored differential pressure condition may include values ​​of about 0.2 bar, less than about 0.15 bar, less than about 0.1 bar, less than about 0.05 bar, less than about 0.01 bar, and / or 0.

[0036] Processor 152 is operable to control the first pump 102 and / or the second pump 112 by sending valve movement signals from controller system 150 based on pump control timing. In one example, when valve 120 switches from a first position to a second position, processor 152 is operable to control the first pump 102 sufficiently to simultaneously stop the fluid flow from the first pump 102. For example, substantially simultaneous stopping of the first pump 102 may occur within 0.0001 seconds to 1 second after signaling to valve 120 to switch to the second position. substantially simultaneous stopping of the first pump 102 may occur within 0.001 seconds to 0.01 seconds after signaling to valve 120 to switch to the second position. substantially simultaneous stopping of the first pump 102 may occur within 0.01 seconds to 0.1 seconds after signaling to valve 120 to switch to the second position. Processor 152 is similarly operable to control the second pump 112 based on these timing parameters.

[0037] Processor 152 is operable to control the first pump 102 and / or the second pump 112 based on the position of valve 120. For example, based on the precise position of one or more components in valve 120, processor 152 is operable to control the first pump 102 sufficiently to simultaneously stop fluid flow from the first pump 102. Similarly, based on the precise position of one or more components in valve 120, processor 152 is operable to control the second pump 112 sufficiently to simultaneously stop fluid flow from the second pump 112. The position of one or more components in valve 120 can be sensed by a position sensor located within valve 120.

[0038] Alternatively or additionally, processor 152 is operable to control the first pump 102 and / or the second pump 112 based on signals from one or more of the first pressure sensor 104 and the second pressure sensor 114. During valve 120 position switching, minor pressure disturbances can be sensed by one or more of the first pressure sensor 104 and the second pressure sensor 114. By receiving and analyzing signals from one or more of the first pressure sensor 104 and the second pressure sensor 114, processor 152 is able to stop the first pump 102 or the second pump 112 based on minor pressure disturbances. Furthermore, processor 152 is operable to control valve 120 sufficiently to switch valve 120 from a first position to a second position to prevent overpressurization of one or more of the first pump 102 (such as a chamber within the first pump 102) and the second pump 112 (such as a chamber within the second pump 112).

[0039] Importantly, system 100 can be used to provide a continuous fluid flow to downstream equipment and processes. Many downstream processes are more efficient and precise when a continuous fluid flow is provided. By controlling the position of valve 120 based on process conditions, such as those indicated by the first pressure sensor 104 and the second pressure sensor 114, system 100 can provide a continuous fluid flow while switching between providing fluid flow from the first pump 102 and the second pump 112. By using two pumps, one pump can provide fluid flow while the other is not operating or pumping.

[0040] Reference Figure 2 The illustration depicts a method 200 for conveying a continuous fluid flow according to some embodiments. Method 200 includes one or more of the following steps:

[0041] Step 202 involves receiving a first fluid through a first inlet in fluid communication with a first pump. Step 202 includes receiving the first fluid through a first inlet such as a first conduit 106 in fluid communication with a first pump, such as a first pump 102. In one example, the first fluid comprises one or more liquids. In another example, the first fluid comprises a solution of a reagent dissolved in a fluid necessary for a downstream process. In yet another example, the first fluid comprises a liquid solvent such as one or more of methanol, acetone, ethanol, benzene, hexane, water, acetonitrile, and isopropanol. The first inlet may be a conduit between the first pump 102 and valve 120.

[0042] Step 204 involves receiving one or more signals from a first pressure sensor indicating the pressure of a first fluid. Step 204 includes receiving one or more signals from a first pressure sensor, such as first pressure sensor 104, indicating the pressure of a first fluid. The signals may include electrical signals indicating the pressure of the first fluid. In one example, the first pressure sensor is downstream of a first pump.

[0043] Step 206 involves receiving one or more signals from a second pressure sensor indicating a second fluid pressure downstream of a second pump, such as a second pump 112. The signals may include electrical signals indicating the second fluid pressure.

[0044] Step 208 involves comparing a first fluid pressure with a second fluid pressure. Step 208 includes comparisons such as determining a difference / percentage between the first and second fluid pressures. For example, a difference of zero means that the first fluid pressure is equal to or approximately equal to the second fluid pressure. To calculate the difference, the second fluid pressure can be subtracted from the first fluid pressure, and vice versa. Comparing the first and second fluid pressures may include determining that the first pressure is approximately equal to the second pressure. In one example, if the percentage difference is between 0.01% and 10%, the controller system may determine that the first pressure is approximately equal to the second pressure. In another example, if the percentage difference is between 0.1% and 5%, the controller system may determine that the first pressure is approximately equal to the second pressure. In yet another example, if the difference is between -1 bar and +1 bar, the controller system may determine that the first pressure is approximately equal to the second pressure. If the difference is less than about 0.2 bar, less than about 0.15 bar, less than about 0.1 bar, less than about 0.05 bar, less than about 0.01 bar, and / or 0, the controller system may determine that the first pressure is approximately equal to the second pressure.

[0045] Step 210, upon determining that the first pressure is approximately equal to the second pressure, (i) operably controls a valve to a position sufficient to switch the valve from a first position to a second position, wherein the first position allows fluid flow of the first fluid through a system outlet, and the second position fluidly connects a first pump, a second pump, and the system outlet; and (ii) stops fluid flow through the first inlet substantially simultaneously with switching the valve from the first position to the second position. Step 210 includes operably controlling a valve, such as valve 120, to a position sufficient to switch the valve from the first position to the second position. In one example, the first position allows fluid flow of the first fluid through a system outlet, such as outlet 130, and the second position fluidly connects a first pump, such as first pump 102, a second pump, such as second pump 112, and the system outlet, such as outlet 130. Alternatively, upon determining that the first pressure is approximately equal to the second pressure, the valve may switch from a third position to the second position. The third position may fluidly connect the second pump to the system outlet. Thus, when the valve switches from the third position to the second position, fluid flow from the second pump may stop substantially simultaneously.

[0046] Stopping fluid flow through the first inlet, substantially simultaneously with switching the valve from the first position to the second position, may include: operably controlling the first pump to stop. Method 200 may further include operably controlling the valve in response to a signal from a valve position sensor adapted to detect the valve position. In one example, the first pump is upstream of the valve. In another example, the second pump is upstream of the valve. In yet another example, method 200 may include continuous fluid flow in the case where both pumps are not used simultaneously. Method 200 may include the use of system 100 and / or the steps of method 200 may be performed in any order.

[0047] Method 200 can provide a fluid flow through a system outlet without a programmed flow transition between the first and second fluids. A programmed flow transition can include a shift in the flow contribution from one pump to another. A programmed flow transition can include providing a flow from a first fluid source through the outlet while simultaneously providing a flow from a second fluid source through the same outlet. For example, a programmed flow transition between the first and second fluids can include a 50 / 50 volume percentage mixture of the two fluids flowing through the outlet.

[0048] Importantly, system 100 and method 200 provide illustrative embodiments of systems and methods capable of providing a continuous flow of fluid through a single outlet while switching fluid sources between two or more pumps. Furthermore, in one example, only one pump needs to provide fluid flow at any given time. Such systems and methods can provide a continuous fluid flow at the outlet without pressure pulsations or fluctuations. Continuous fluid flow is preferred because the outlet can be connected to downstream analytical devices. These analytical devices are less efficient or accurate if the fluid is supplied with interrupted flow and / or pressure fluctuations.

[0049] Figure 3 The illustration shows a fluid delivery system 300 for continuous fluid flow according to some embodiments. System 300 includes an inlet 302, an optional reservoir 304, a first pump 310, a first pressure sensor 316, a first conduit 318, a second pump 320, a second pressure sensor 326, a second conduit 328, a shear valve 340, an optional outlet conduit 380, and an optional downstream system 382. In one example, the first pump 310 includes a first chamber 312 and a first piston 314. In another example, the second pump 320 includes a second chamber 322 and a second piston 324. The first pump 310 and the second pump 320 may be fluidly connected to the first pressure sensor 316 and the second pressure sensor 326, respectively. The first pressure sensor 316 and the second pressure sensor 326 may be upstream or downstream of the outlets of the first pump 310 and the second pump 320, respectively. The first conduit 318 and the second conduit 328 may fluidly connect the first pump 310 and the second pump 320 to the shear valve 340, respectively. When the shear valve 340 is in the first position 350, the first pump 310 can distribute fluid, while the second pump 320 can optionally pressurize.

[0050] The shear valve 340 includes a rotor and a stator. The rotor may include two rotor slots and / or consist of two rotor slots. The rotor slots are sufficient to allow fluid to pass through them. These rotor slots can rotate approximately 12 positions in 30-degree increments. The stator may include four stator orifices and / or consist of four stator orifices. The stator orifices are sufficient to allow fluid to pass through them. Therefore, the shear valve 340 includes one or more of a first rotor slot 360, a second rotor slot 362, a first stator orifice 370, a second stator orifice 372, a third stator orifice 374, and a fourth stator orifice 376. The shear valve 340 may include a valve actuator (not shown) adapted to rotate the rotor. A controller may be configured to send signals to the valve actuator to operate the rotor. The rotor can rotate relative to the stator about an axis (such as axis 366). Therefore, one or more of the first rotor slot 360 and the second rotor slot 362 can rotate relative to one or more of the first stator aperture 370, the second stator aperture 372, the third stator aperture 374, and the fourth stator aperture 376. One or more of the first rotor slot 360 and the second rotor slot 362 can rotate in 30-degree increments, as shown by reference numeral 364.

[0051] The first stator orifice 370 is in fluid communication with the first pump 310 and / or the first pressure sensor 316. The second stator orifice 372 is in fluid communication with the second pump 320 and / or the second pressure sensor 326. The third stator orifice 374 is in fluid communication with the inlet 302 and / or an optional reservoir 304 (such as one or more mobile phase reservoirs). The fourth stator orifice 376 may be in fluid communication with the outlet line 380. Therefore, the fourth stator orifice 376 may be in fluid communication with an optional downstream system 382. Figure 3 As shown, the shear valve 340 is shown in a first position 350. In the first position 350, the first rotor slot 360 is fluidly connected to the first stator orifice 370 and the fourth stator orifice 376. In the first position 350, the second rotor slot 362 is in fluid communication with the third stator orifice 374, while the second stator orifice 372 is isolated. In the first position 350, the first pump 310 can supply fluid flow to the outlet line 380. When the first pump 310 supplies fluid flow to the outlet line 380, the second pump 320 can pressurize the fluid in the second chamber 322 by moving / pushing the second piston 324 into the second chamber 322.

[0052] Figure 4 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments. Figure 4A shear valve 340 is shown in a second position 450. In the second position 450, a first rotor slot 360 is fluidly connected to a first stator orifice 370, a second stator orifice 372, and a fourth stator orifice 376. In the second position 450, a second rotor slot 362 is in fluid communication with a third stator orifice 374. The valve actuator may have rotated the rotor 30 degrees (e.g., clockwise) from the first position 350 to the second position 450. In one example, in the second position 450, a first pump 310 or a second pump 320 may supply fluid flow to an outlet line 380. For example, as... Figure 4 As shown, when the shear valve 340 is in the second position 450, the second pump 320 supplies all fluid flow to the outlet line 380.

[0053] Figure 5 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments. Figure 5 A shear valve 340 is shown in a third position 550. In the third position 550, a first rotor slot 360 is fluidly connected to a second stator orifice 372 and a fourth stator orifice 376. In the third position 550, a second rotor slot 362 is fluidly connected to a first stator orifice 370 and a third stator orifice 374. The valve actuator may have rotated the rotor 60 degrees (e.g., clockwise) from the second position 450 to the third position 550. In one example, in the third position 550, a second pump 320 supplies fluid flow to the outlet line 380. In another example, in the third position 550, a first pump 310 may draw fluid sufficiently to fill the first chamber 312 with fluid from an optional reservoir 304. Importantly, the transition from the second position 450 to the third position 550 does not inhibit or alter the flow of fluid from the second pump 320. Moving to the third position 550 does allow the first pump 310 to begin pumping, while the second pump 320 continues to supply fluid flow to the fourth stator orifice 376. In the third position 550, the first pump 310 can pump at a higher rate than the second pump 320 to achieve complete pumping before the second pump 320 runs out of fluid.

[0054] Figure 6 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments. Figure 6A shear valve 340 is shown in a fourth position 650. The valve actuator may have rotated the rotor 30 degrees (e.g., counterclockwise) from a third position 550 to the fourth position 650. In the fourth position 650, the first rotor slot 360 is fluidly connected to the second stator orifice 372 and the fourth stator orifice 376. In the fourth position 650, the second rotor slot 362 is in fluid communication with the third rotor slot 374. Furthermore, in the fourth position 650, the first stator orifice 370 may be isolated. For example, the first stator orifice 370 may be isolated from the rotor, such as from the first rotor slot 360 and the second rotor slot 362. Since the first rotor orifice 370 can be isolated in the fourth position 650, the first pump 310 can be pressurized in the fourth position 650. In one example, the first pump 310 pressurizes by moving the first piston 314 into the first chamber 312. When the first pump 310 pressurizes and / or after the first pump 310 has been pressurized, the second pump 320 can supply fluid flow to the outlet line 380 through the fourth stator orifice 376.

[0055] Figure 7 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments. Figure 7 A shear valve 340 is shown in a second position 450. In the second position 450, a first rotor slot 360 is fluidly connected to a first stator orifice 370, a second stator orifice 372, and a fourth stator orifice 376. In the second position 450, a second rotor slot 362 is in fluid communication with a third stator orifice 374. The valve actuator may have rotated the rotor 30 degrees (e.g., clockwise) from the fourth position 650 to the second position 450. In one example, in the second position 450, a first pump 310 or a second pump 320 may supply fluid flow to an outlet line 380. For example, as... Figure 7 As shown, when the shear valve 340 is in the second position 450, the first pump 310 supplies all fluid flow to the outlet line 380.

[0056] Figure 8 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments. Figure 8A shear valve 340 is shown in a fifth position 750. The valve actuator may have rotated the rotor 90 degrees (e.g., counterclockwise) from a fourth position 650 to the fifth position 750. In the fifth position 750, a first rotor slot 360 fluidly connects a first stator orifice 370 and a fourth stator orifice 376. In the fifth position 750, a second rotor slot 362 fluidly connects a second stator orifice 372 and a third stator orifice 374. In one example, in the fifth position 750, a first pump 310 supplies fluid flow to an outlet line 380 through the fourth stator orifice 376. In another example, in the fifth position 750, a second pump 320 can draw fluid sufficiently to fill a second chamber 322 with fluid from an optional reservoir 304. The drawing rate of the second pump 320 may be higher than the dispensing rate of the first pump 310, so that the second pump 320 is completely drawn before the first pump 310 has fully dispensed all the fluid from the first chamber 312.

[0057] The valve actuator is capable of rotating the first rotor slot 360 and the second rotor slot 362 to any position among the first position 350, second position 450, third position 550, fourth position 650, and fifth position 750. Therefore, the valve actuator is capable of rotating the first rotor slot 360 and the second rotor slot 362 to any position among the first position 350, second position 450, third position 550, fourth position 650, and fifth position 750 in any order. In one example, the valve actuator is capable of rotating the first rotor slot 360 and the second rotor slot 362 from the fifth position 750 to the first position 350. In another example, the valve actuator is capable of rotating the first rotor slot 360 and the second rotor slot 362 from the fourth position 650 to the second position 450. In a non-limiting example, the valve actuator is capable of rotating the first rotor slot 360 and the second rotor slot 362 in the following order: first position 350, second position 450, third position 550, fourth position 650, second position 450, fifth position 750. The valve actuator is able to rotate the shear valve 340 from the fifth position 750 to the first position 350 to restart the sequence.

[0058] System 300 is capable of operating at pressures consistent with downstream devices. In one example, system 300 is capable of operating at pressures between 1 bar and 500 bar. In another example, system 300 is capable of operating at pressures between 1 bar and 50 bar. In yet another example, system 300 is capable of operating at pressures between 1 bar and 10 bar. System 300 is capable of supplying liquid flow to downstream devices at a variety of flow rates. The downstream device can determine the desired liquid flow rate. In one example, system 300 is capable of supplying liquid flow to downstream devices at flow rates ranging from about 1 µL / min to 10 mL / min. System 300 is preferably configured to accommodate the flow rates required for any particular application. The needs of the downstream system determine the flow rate, and therefore determine pumping capacity, valve pressure ratings, and slot sizes, etc.

[0059] Figure 9 The figure illustrates a fluid delivery system 300 for continuous fluid flow according to some embodiments. Figure 9 The illustration shows that system 300 may include one or more controller systems 850 that communicate with one or more other components within system 300. For example, the controller system may include a processor 852 and a memory 854 (such as non-transient memory), and may be communicatively coupled (such as via electrical communication) to one or more of the first pump 310, the first pressure sensor 316, the second pump 320, the second pressure sensor 326, and the shear valve 340. The processor 852 may communicate with and access the memory 854 to the extent necessary to run programs or access system settings. Depending on the type of sensor, the first pressure sensor 316 and the second pressure sensor 326 may communicate electrically with the first pump 310 and the second pump 320, respectively.

[0060] The controller system 850 is capable of receiving one or more signals from one or more components in the system 300. For example, the controller system 850 may receive a signal indicating a first pressure from a first pressure sensor 316 and a signal indicating a second pressure from a second pressure sensor 326. Although in Figure 9A single controller system 850 is shown, but the first pump 310, the second pump 320, and the shear valve 340 may each include a separate controller. These separate controllers may communicate with a parent controller such as controller system 850. In this example, controller system 850 will monitor pump position and valve position, as well as output from pressure sensors. Controller system 850 may receive one or more signals from the first pump 310 and the second pump 320 indicating pump position, pump speed, and / or pump pressure. For example, controller system 850 may receive one or more signals from the first pump 310 and the second pump 320 indicating whether the individual pumps are pumping, suctioning, pressurizing, and / or on or off. Alternatively, controller system 850 may be able to receive signals from a valve position sensor adapted to detect the rotor position of shear valve 340.

[0061] Processor 852 is operable to control shear valve 340 to rotate the rotor to a third position 550, fluidly connecting the first rotor slot 360, the second stator orifice 372, and the fourth stator orifice 376. Processor 852 is operable to control shear valve 340 to rotate the rotor to a fourth position 650, fluidly connecting the first rotor slot 360, the second stator orifice 372, and the fourth stator orifice 376, while isolating the first stator orifice 370 from the rotor. Processor 852 is operable to control shear valve 340 to rotate the rotor to a fifth position 750, fluidly connecting the first rotor slot 360, the first stator orifice 370, and the fourth stator orifice 376. Processor 852 is operable to control shear valve 340 to rotate the rotor to a fifth position 750, fluidly connecting the second rotor slot 362, the second stator orifice 372, and the third stator orifice 374. In response to a signal from a valve position sensor adapted to detect the rotor position, the processor 852 is operable to control the shear valve 340. For example, the valve position sensor is adapted to detect whether the rotor is in a first position 350, a second position 450, a third position 550, a fourth position 650, or a fifth position 750.

[0062] In response to the first pressure being approximately equal to the second pressure, processor 852 is operable to control shear valve 340 sufficiently to switch valve 340 from a first position 350 to a second position 450. Processor 852 is capable of determining whether the first pressure is approximately equal to the second pressure based on stored differential pressure conditions. For example, processor 852 can compare the differential pressure between the first and second pressures with stored differential pressure conditions to determine whether the pressures are approximately equal. In one example, if the differential pressure between the first and second pressures is a value included in the stored differential pressure conditions, processor 852 determines that the pressures are approximately equal. Alternatively or additionally, processor 852 is operable to control shear valve 340 based on the flow rates and volumes of the first pump 310 and the second pump 320. For example, processor 852 can operable to control shear valve 340 to prevent complete pump depletion by receiving signals indicating the flow rates of the first pump 310 and / or the second pump 320.

[0063] In many embodiments, the stored differential pressure condition can be a percentage value. In one example, the stored differential pressure condition includes a percentage value between 0.01% and 10%. In another example, the stored differential pressure condition includes a percentage value between about 0.1% and about 5%. In yet another example, the stored differential pressure condition includes a percentage value between about 0.5% and about 2%. The stored differential pressure condition can include percentage values ​​less than 5%, less than 4%, less than 3%, less than 2%, or less than 1%.

[0064] In other embodiments, the stored differential pressure condition may include a range of values. In one example, the stored differential pressure condition includes values ​​between -0.2 bar and +0.2 bar. In another example, the stored differential pressure condition includes values ​​between -0.1 bar and +0.1 bar. In yet another example, the stored differential pressure condition includes values ​​between -0.05 bar and +0.05 bar. For example, the stored differential pressure condition may include values ​​of about 0.2 bar, less than about 0.15 bar, less than about 0.1 bar, less than about 0.05 bar, less than about 0.01 bar, and / or 0.

[0065] In a non-limiting example, if the controller system 850 determines that a stored differential pressure condition is met, the controller system 850 sends a command to the shear valve controller communicating with the shear valve 340 to switch the position using the valve actuator. Immediately following this command, the controller system 850 may send a command to the pump controller communicating with the first pump 310 or the second pump 320 to stop the first pump 310 or the second pump 320. In another example, the next command from the controller system 850 is to signal to switch the shear valve 340 to a position that fluidly connects the first pump 310 or the second pump 320 to the third stator orifice 374.

[0066] Processor 852 is operable to control the first pump 310 and / or the second pump 320 by sending valve movement signals from controller system 850 based on pump control timing. In one example, when shear valve 340 switches from a first position 350 to a second position 450, processor 852 is operable to control the first pump 310 sufficiently to simultaneously stop the fluid flow from the first pump 310. For example, substantially simultaneous stopping of the first pump 310 may occur within 0.0001 seconds to 1 second after signaling to shear valve 340 to switch to the second position 450. Substantially simultaneous stopping of the first pump 310 may occur within 0.001 seconds to 0.01 seconds after signaling to shear valve 340 to switch to the second position 450. Substantially simultaneous stopping of the first pump 310 may occur within 0.01 seconds to 0.1 seconds after signaling to shear valve 340 to switch to the second position 450. Processor 852 is similarly operable to control the second pump 320 based on these timing parameters.

[0067] Processor 852 is operable to control the first pump 310 and / or the second pump 320 based on the position of shear valve 340. Processor 852 is operable to control the first pump 310 based on the precise position of one or more components in shear valve 310, sufficient to simultaneously stop fluid flow from the first pump 310. For example, processor 852 can control the first pump 310 based on the position of the first rotor slot 360 and / or the second rotor slot 362 relative to one or more of the first stator orifice 370, the second stator orifice 372, the third stator orifice 374, and the fourth stator orifice 376, sufficient to simultaneously stop fluid flow from the first pump 310. The position of one or more components in the valve can be sensed by a position sensor located within the valve. In one example, the position sensor is capable of sensing when the rotor begins to move through the orifice.

[0068] Alternatively or additionally, the processor 852 can operatively control the first pump 310 and / or the second pump 320 based on signals from one or more of the first pressure sensor 316 and the second pressure sensor 326. During the position switching of the shear valve 340, minor pressure disturbances can be sensed by one or more of the first pressure sensor 316 and the second pressure sensor 326. By receiving and analyzing signals from one or more of the first pressure sensor 316 and the second pressure sensor 326, the processor 852 can stop the first pump 310 or the second pump 320 based on the minor pressure disturbance. Similarly, the processor 852 can operatively control the second pump 320 based on sensed pressure disturbances. Furthermore, the processor 852 can operatively control the shear valve 340 sufficiently to switch the shear valve 340 from a first position 350 to a second position 450 to prevent overpressurization of one or more of the first pump 310 (such as the first chamber 312) and the second pump 320 (such as the second chamber 322).

[0069] Similarly, at the fourth position 650, when the stored differential pressure condition is met, the processor 852 is operable to control the second pump 320. The processor 852 can send a signal to the valve actuator to switch the shear valve 340 from the fourth position 650 to the second position 450. When the shear valve 340 switches from the fourth position 650 to the second position 450, the second pump 320 can be controlled to stop dispensing via a command from the controller system 850. In one example, the processor 852 is operable to control the second pump 320 based on the precise position of one or more components in the shear valve 340, sufficient to simultaneously stop the fluid flow from the second pump 320.

[0070] Importantly, system 300 is capable of efficiently providing a continuous flow to downstream processes. Unlike check valves, which may experience undesirable flow changes when switching between pumps, system 300 can switch between providing flow from first pump 310 and second pump 320 without pressure pulsations. Unlike programmed flow transitions where both pumps provide flow to the downstream system, system 300 can provide a continuous flow, supplying flow from only one pump at a time. These flow transitions typically require numerous expensive controllers and precise pump speed and / or flow rate monitoring to control them. By using the controller system and shear valve of this invention to provide a continuous fluid flow, downstream processes, such as analytical equipment, can be operated more precisely and efficiently.

[0071] Reference Figure 10 The illustration shows a method 900 for controlling a shear valve for continuous fluid delivery according to some implementation. Method 900 includes one or more of the following steps:

[0072] Step 902 involves receiving one or more signals from a first pump pressure sensor indicating a first pressure generated by the first pump. Step 902 includes receiving one or more signals from a first pump pressure sensor, such as a first pressure sensor 316, indicating a first pressure generated by a first pump, such as a first pump 310. These signals may include electrical signals indicating the first pressure.

[0073] Step 904 involves receiving one or more signals from a second pump pressure sensor indicating a second pressure generated by the second pump. Step 904 includes receiving one or more signals from a second pump pressure sensor, such as second pressure sensor 326, indicating a second pressure generated by a second pump, such as second pump 320. These signals may include electrical signals indicating the second pressure.

[0074] Step 906 involves comparing the first pressure with the second pressure. Step 906 includes comparing the first pressure with the second pressure, such as determining a difference / percentage between the first pressure and the second pressure. For example, a difference of zero means that the first pressure is equal to or approximately equal to the second pressure. To calculate the difference, the second pressure can be subtracted from the first pressure, and vice versa. Comparing the first pressure with the second pressure may include determining that the first pressure is approximately equal to the second pressure.

[0075] If the percentage difference equals the stored differential pressure condition, the controller system can determine that the first pressure is approximately equal to the second pressure. In many embodiments, the stored differential pressure condition can be a percentage value. In one example, the stored differential pressure condition includes a percentage value between 0.01% and 10%. In another example, the stored differential pressure condition includes a percentage value between about 0.1% and about 5%. In yet another example, the stored differential pressure condition includes a percentage value between about 0.5% and about 2%. The stored differential pressure condition can include percentage values ​​less than 5%, less than 4%, less than 3%, less than 2%, or less than 1%.

[0076] In other embodiments, if the difference equals a stored differential pressure condition between -0.2 bar and +0.2 bar, the controller system can determine that the first pressure is approximately equal to the second pressure. In another example, if the difference equals a stored differential pressure condition between -0.1 bar and +0.1 bar, the controller system can determine that the first pressure is approximately equal to the second pressure. In yet another example, if the difference equals a stored differential pressure condition between -0.05 bar and +0.05 bar, the controller system can determine that the first pressure is approximately equal to the second pressure. If the difference is less than about 0.2 bar, less than about 0.15 bar, less than about 0.1 bar, less than about 0.05 bar, less than about 0.01 bar, and / or 0, the controller system can determine that the first pressure is approximately equal to the second pressure.

[0077] Step 908, when the first pressure is determined to be approximately equal to the second pressure, operably controls a shear valve to rotate the rotor from a first position to a second position, thereby fluidly connecting the first rotor slot, the first stator orifice, the second stator orifice, and the outlet. Step 908 includes operably controlling a shear valve, such as shear valve 340, to rotate the rotor from the first position to a second position, such as second position 450. The first rotor slot may be the first rotor slot 360. The first stator orifice may be the first stator orifice 370, the second stator orifice may be the second stator orifice 372, and the outlet may be the fourth stator orifice 376 or the outlet conduit 380.

[0078] Step 910, substantially simultaneously with rotating the rotor to the second position, operably controls the first pump to stop, step 910 including operably controlling the first pump, such as the first pump 310, to stop substantially simultaneously with rotating the rotor to the second position, such as the second position 450.

[0079] Stopping may include sending a signal to the pump to stop its movement or rotation. In one example, stopping includes shutting off the pump. In another example, stopping includes stopping the output flow of fluid from the pump. For example, stopping the first pump substantially simultaneously may occur within 0.0001 seconds to 1 second of switching to the second position. Stopping the first pump substantially simultaneously may occur within 0.001 seconds to 0.01 seconds of switching to the second position. Stopping the first pump substantially simultaneously may occur within 0.01 seconds to 0.1 seconds of switching to the second position. Stopping the first pump substantially simultaneously may occur at exactly the same time as switching to the second position. Alternatively, the second pump may be operatively controlled to stop substantially simultaneously with rotating the rotor to the second position. The steps of method 900 may be performed in any order.

[0080] Operable control of stopping the first pump may include controlling the first pump based on the rotor position. The position of one or more components in the valve may be sensed by a position sensor located within the valve. In one example, the position sensor is capable of sensing when the rotor begins to move through the orifice. In one example, the first pump is controlled to stop once the valve position sensor has sensed that the valve is in a second position. Alternatively or additionally, the first pump may be controlled to stop if one or more of the first and second pressure sensors sense a small pressure disturbance.

[0081] Importantly, method 900 provides a continuous fluid flow to one or more downstream devices while switching fluid flows. Therefore, a single pump can continuously supply 100% fluid flow to downstream devices. This allows auxiliary pumps to draw from reservoirs while the main pump is distributing. Furthermore, method 900 provides a continuous fluid flow without pressure pulsations and / or programmed flow transitions. When a continuous fluid flow is provided, downstream devices operate more precisely and efficiently.

[0082] While this disclosure has been described with reference to one or more exemplary embodiments, those skilled in the art will understand that various changes can be made without departing from the scope of the embodiments, and equivalents can replace its elements. Furthermore, many modifications can be made to adapt particular situations or materials to the teachings of the embodiments without departing from its essential scope. Therefore, this disclosure is not intended to be limited to the disclosed embodiments, but rather to include all embodiments falling within the scope of the appended claims. Various examples have been described. These and other examples are within the scope of the following claims.

Claims

1. A fluid transport system for continuous fluid flow, comprising: First pump; A first pump pressure sensor is used to detect the fluid pressure associated with the chamber of the first pump; Second pump; A second pump pressure sensor is used to detect the fluid pressure associated with the chamber of the second pump; One or more mobile phase storage devices; A shear valve comprising a rotor and a stator, the rotor being rotatable about an axis relative to the stator, the rotor including a first rotor slot, the stator including a first stator orifice, a second stator orifice, a third stator orifice, and a fourth stator orifice, wherein the first stator orifice is in fluid communication with a first pump, the second stator orifice is in fluid communication with a second pump, the third stator orifice is in fluid communication with one or more fluid phase reservoirs, and the fourth stator orifice is in fluid communication with an outlet; and The controller system includes a processor and a memory, and is communicatively connected to the first pump, the first pump pressure sensor, the second pump, the second pump pressure sensor, and the shear valve. The controller system receives signals indicating a first pressure from the first pump pressure sensor and signals indicating a second pressure from the second pump pressure sensor. The processor is operatively controllable in response to the first pressure being approximately equal to the second pressure, such that the shear valve rotates the rotor from a first position to a second position fluidly connecting the first rotor slot, the first stator orifice, the second stator orifice, and the outlet, while simultaneously operatively controlling the first pump to substantially simultaneously stop the fluid flow from the first pump.

2. The system according to claim 1 further includes a second rotor slot, the second rotor slot being in fluid communication with the third stator orifice in the second position.

3. The system according to claim 1, wherein, The processor is operatively capable of controlling the shear valve to rotate the rotor to a third position that fluidly connects the first rotor slot, the second stator orifice, and the outlet.

4. The system according to claim 3 further includes a second rotor slot, the second rotor slot being in fluid communication with the first stator orifice and the third stator orifice in the third position.

5. The system according to claim 1, wherein, The processor is operatively capable of controlling the shear valve to rotate the rotor to a fourth position that fluidly connects the first rotor slot, the second stator orifice, and the outlet, while isolating the first stator orifice from the rotor.

6. The system according to claim 1, wherein, The processor is capable of operatively controlling the shear valve to rotate the rotor to a fifth position in which the first rotor slot, the first stator orifice, and the outlet are fluidly connected.

7. The system according to claim 1, wherein, The processor is operatively capable of controlling the shear valve to rotate the rotor to a fifth position that fluidly connects the second rotor slot, the second stator orifice, and the third stator orifice.

8. The system according to claim 1, wherein, The processor is capable of operatively controlling the shear valve in response to a signal from a valve position sensor adapted to detect the rotor position.

9. The system according to claim 1, wherein, After the rotor has rotated to the second position, the system can operatively control the first pump to stop the fluid flow from the first pump.

10. The system according to claim 1, wherein, The first pump and the second pump are selected from reciprocating pumps and syringe pumps.

11. The system according to claim 1, wherein, The processor is able to determine whether the first fluid pressure is approximately equal to the second fluid pressure based on stored differential pressure conditions.

12. A method for controlling a shear valve for fluid transport, comprising: Receive one or more signals from the first pump pressure sensor indicating the first pressure generated by the first pump; Receive one or more signals from the second pump pressure sensor indicating the second pressure generated by the second pump; Compare the first pressure with the second pressure; When the first pressure is determined to be approximately equal to the second pressure, the shear valve can be operatively controlled to rotate the rotor from a first position to a second position in which the first rotor slot, the first stator orifice, the second stator orifice, and the outlet are fluidly connected. as well as The first pump can be operatively stopped substantially simultaneously with rotating the rotor to the second position.

13. The method according to claim 12, wherein, The processor is capable of operatively controlling the shear valve in response to a signal from a valve position sensor adapted to detect the rotor position.

14. The method of claim 12, wherein once the rotor has rotated to the second position, the first pump can be operatively controlled to stop such that the fluid flow from the first pump ceases.

15. The method according to claim 12, wherein, The shear valve also includes a third stator orifice.

16. The method according to claim 15, wherein, In the second position, the third stator orifice is in fluid communication with the second rotor slot.

17. The method according to claim 15, wherein, The processor is capable of operatively controlling the shear valve to rotate the rotor to a third position where the second stator orifice and the outlet are fluidly connected.

18. The method according to claim 12, wherein, The first pump and the second pump are selected from reciprocating pumps and syringe pumps.

19. The method according to claim 12, wherein, The first pump and the second pump are upstream of the shear valve.

20. The method of claim 12, further comprising determining whether the first pressure is approximately equal to the second pressure based on stored differential pressure conditions.

21. A fluid transport system for continuous fluid flow, comprising: The first inlet is in fluid communication with the first pump; A first pressure sensor is used to detect the first fluid pressure downstream of the first pump; The second inlet is in fluid communication with the second pump; A second pressure sensor is used to detect the pressure of a second fluid downstream of the second pump; exit; A valve, comprising a first position and a second position, wherein the first position fluidly connects a first inlet to an outlet, and the second position fluidly connects the first inlet, the second inlet, and the outlet; and A controller system, comprising a processor and a memory, wherein the controller system is communicatively connected to the first pump, the second pump, the first pressure sensor, the second pressure sensor, and the valve. The controller system receives signals from the first pressure sensor indicating the first fluid pressure and from the second pressure sensor indicating the second fluid pressure. The processor is programmed to guide the valve from the first position to the second position in response to the first fluid pressure being approximately equal to the second fluid pressure, and substantially simultaneously stop fluid flow through the first inlet.

22. The system according to claim 21, wherein, The processor determines whether the first fluid pressure is approximately equal to the second fluid pressure by comparing the difference between the first fluid pressure and the second fluid pressure with a stored pressure difference value.

23. The system according to claim 21, wherein, The processor is capable of operatively controlling the valve in response to a signal from a valve position sensor adapted to detect the valve position.

24. The system according to claim 21, wherein, Stopping the flow through the first inlet includes: operably controlling the first pump to stop.

25. The system according to claim 21, wherein, The first pump and the second pump are upstream of the valve.

26. The system according to claim 21, wherein, The first fluid and the second fluid are of the same composition.

27. A method for conveying fluid in a continuous fluid transport system, the method comprising: The first fluid is received through a first inlet that is in fluid communication with the first pump; Receive one or more signals from a first pressure sensor indicating the pressure of a first fluid; Receive one or more signals from the second pressure sensor indicating the pressure of the second fluid downstream of the second pump; Compare the first fluid pressure with the second fluid pressure; as well as When it is determined that the first pressure is approximately equal to the second pressure (i) Operable to control the valve to switch the valve from a first position to a second position, wherein the first position allows fluid flow of the first fluid through the system outlet, and the second position fluidly connects the first pump, the second pump, and the system outlet; as well as (ii) At substantially the same time as switching the valve from the first position to the second position, stop the flow of fluid through the first inlet.

28. The method according to claim 27, wherein, Stopping the fluid flow through the first inlet includes operatively controlling the first pump to stop.

29. The method of claim 27, further comprising operably controlling the valve in response to a signal from a valve position sensor adapted to detect the position of the valve.

30. The method according to claim 27, wherein, The first pump and the second pump are upstream of the valve.

31. The method of claim 27, further comprising determining whether the first pressure is approximately equal to the second pressure by comparing the difference between the first pressure and the second pressure with a stored differential pressure value.

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