A clinical platelet aggregation detection carrier

Abstract

The present application relates to the technical field of platelet aggregation detection, and specifically discloses a clinical platelet aggregation detection carrier, which comprises an instrument body and further comprises: a detection assembly arranged inside the instrument body, which is used for detecting different types of samples of lipemia, anemia and normal blood and selecting centrifugal operation of the blood samples; the detection assembly can detect different types of samples of lipemia, anemia and normal blood, and can automatically indicate whether centrifugal operation of the blood is needed according to the types of the detected samples; through the sampling assembly, the blood samples at different layer depths can be automatically adjusted according to the lipemia, anemia and normal blood samples detected by the detection assembly; through the agent adding assembly, the amount of the added inducing agent can be automatically adjusted according to the sample amount taken by the sampling assembly, so that the concentration of the mixed inducing agent reaches the specified range, thereby improving the detection accuracy of the platelet aggregation degree.

Description

Technical Field

[0001] This invention relates to the field of platelet aggregation detection technology, specifically to a clinical platelet aggregation detection carrier. Background Technology

[0002] Platelet aggregation testing is a core indicator for assessing thrombotic diseases, hemorrhagic diseases, and the efficacy of antiplatelet drugs. The accuracy of the results is highly dependent on sample quality and testing standardization. Platelet aggregation testing devices (also known as platelet aggregators) are medical devices used to detect the degree of platelet aggregation. They belong to Class II medical devices in clinical laboratory equipment and are classified as hematological analysis equipment.

[0003] When detecting platelet aggregation using platelet aggregation detection devices, individual differences exist in clinical blood samples. For example, the physical properties of the plasma layer and the distribution of platelets after centrifugation differ between lipemic, anemic, and normal blood samples. Existing platelet aggregation detection devices cannot adjust the sampling depth according to different types of blood samples, nor can they adaptively adjust the amount of inducing agent added according to the sample volume. This may result in the addition of too much or too little inducing agent. If too much inducing agent is added, a sample with a slight functional defect may also show a large degree of aggregation, leading to false negative results and masking the true pathological condition. Furthermore, for normal platelets, too much inducing agent may also trigger non-physiological and violent reactions. If too little inducing agent is added, platelets cannot be effectively activated, resulting in a weak or non-existent reaction, which will affect the detection of platelet aggregation. Therefore, we propose a clinical platelet aggregation detection carrier. Summary of the Invention

[0004] The purpose of this invention is to provide a clinical platelet aggregation detection carrier to solve the problems mentioned in the background art regarding existing platelet aggregation detection devices, which cannot adjust the corresponding sampling depth according to different types of blood samples, and cannot adaptively adjust the amount of inducing agent added according to the sample volume. There may be cases where too much or too little inducing agent is added. If too much inducing agent is added, a sample with a slight functional defect may also show a large degree of aggregation, resulting in a false negative result and masking the true pathological state. Moreover, for normal platelets, too much inducing agent may also trigger non-physiological severe reactions. If too little inducing agent is added, platelets cannot be effectively activated, resulting in a weak reaction or no reaction, which will affect the detection of platelet aggregation.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a clinical platelet aggregation detection carrier, comprising: an instrument body, a guide frame disposed inside the instrument body, a first guide rail disposed on the guide frame, a second guide rail disposed on the first guide rail, an mounting component disposed on the second guide rail, and a sampling needle disposed on the mounting component;

[0006] It also includes: a detection component, which is located inside the instrument body. The detection component is used to detect different types of blood samples, such as lipemia, anemia, and normal blood, and to select the blood sample centrifugation operation.

[0007] The sampling component is located inside the instrument body. The sampling component automatically adjusts to collect blood samples at different depths based on the lipid blood, anemia, and normal blood samples detected by the detection component.

[0008] The dosing component is located inside the instrument body. The dosing component automatically adjusts the amount of inducing agent added based on the sample volume collected by the sampling component.

[0009] The detection component includes a mounting block fixedly connected to the inner wall of the instrument body, a support block fixedly connected to the bottom of the instrument body on the lower side of the mounting block, a sleeve fixedly connected to the lower side of the mounting block, a first sample tube on the inner side of the mounting block, the sleeve and the support block, a mounting plate fixedly connected to the lower side of the mounting block, a mounting shell and a camera fixedly connected to one side of the mounting plate, a photoelectric detection sensor fixedly connected to the inner side of the mounting shell, and an indicator light on the upper side of the mounting block.

[0010] The instrument body contains a centrifugation module and a waste liquid box.

[0011] The sampling component includes a first bracket and a second bracket fixedly connected to the inside of the instrument body. A second sample tube is provided on the second bracket. A connector is fixedly connected to one side of the second guide rail. Three first switches are provided on the side of the connector near the mounting component. A first pressure block is fixedly connected to one side of the mounting component.

[0012] The dosing assembly includes a support plate fixedly connected to the inner wall of the instrument body, a cylinder fixedly connected to the support plate, a connecting pipe fixedly connected to the lower side of the cylinder, a solenoid valve installed on the connecting pipe, a receiving cylinder provided on the lower side of the connecting pipe, a limit base provided on the lower side of the receiving cylinder, a limit base fixedly connected to the inner bottom of the instrument body, and a pressure sensor provided on the limit base.

[0013] The first guide rail is fixedly connected to a second pressure block, the inner wall of the instrument body is provided with a third switch, the upper side of the first guide rail is provided with a fourth switch, and the second guide rail is fixedly connected to a third pressure block on one side.

[0014] The support plate has a housing fixedly connected to its upper side, a second electromagnet fixedly connected to its inner side, a sliding member slidably arranged at the bottom of its inner side, a third electromagnet fixedly connected to one side of the sliding member that repels the second electromagnet, and a distance sensor arranged on one side of the mounting component.

[0015] The sliding member is fixedly connected to a connecting shell on one side, and a fourth electromagnet is fixedly connected to the inside of the connecting shell. A toothed block that attracts the fourth electromagnet is slidably arranged inside the connecting shell. A second spring that is fixedly connected to the connecting shell is symmetrically fixed to the inside of the toothed block. A toothed rod is fixedly connected to the inside of the shell, and the toothed rod is located on one side of the connecting shell. The toothed rod cooperates with the toothed block.

[0016] The slider is slidably mounted on the upper side of the slider, a third spring is fixedly connected to one side of the slider and fixedly connected to the inner wall of the housing, a second magnet that repels the third electromagnet is fixedly connected to the other side of the slider, and a second switch is mounted on one side of the slider.

[0017] The device includes a first electromagnet fixedly connected to the inner side of the housing, a movable block slidably disposed on the inner side of the housing, a first spring fixedly connected to the inner wall of the housing on one side of the movable block, a first magnet repelling the first electromagnet fixedly connected to the other side of the movable block, a pressing component fixedly connected to one side of the movable block, and a magnetic stirring module disposed on the inner side of the instrument body.

[0018] The present invention has at least the following beneficial effects:

[0019] This invention utilizes a detection component to detect different types of blood samples, including those with lipemia, anemia, and normal blood. It can automatically indicate whether blood centrifugation is necessary based on the sample type. For anemia samples, characterized by a reduced red blood cell count or decreased hemoglobin content, leading to a decreased hematocrit, whole blood or deep sampling is required to ensure the representativeness of platelet counts and maintain the physiological matrix environment. Centrifugation is unnecessary to prevent significant reduction in the red blood cell layer volume and relative thickening of the plasma layer caused by centrifugation, thus avoiding false negatives (misinterpreted as platelet dysfunction) or test failures due to abnormal centrifugation stratification. The sampling component allows for the determination of whether blood samples are lipemia, anemia, or normal blood based on the type detected by the detection component. For normal blood samples, the system automatically adjusts to collect samples from different depths. For lipemic samples, which may exhibit pseudo-low aggregation, the upper chylous layer is discarded after centrifugation, and the clear PRP (platelet-rich plasma) layer is collected. For anemic samples, the sample is gently inverted and mixed to ensure uniform distribution of the anticoagulant, and the mixed whole blood is used for testing (deep sampling). For normal blood samples, the upper PRP layer is collected after centrifugation. The dosing component automatically adjusts the amount of inducing agent added based on the sample volume collected by the sampling component, ensuring that the concentration of the added inducing agent (the ratio of the added inducing agent mass to the total volume of the sample and the added inducing agent) reaches the specified range, thereby improving the accuracy of platelet aggregation detection. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0021] Figure 2This is a structural schematic diagram of the invention from another perspective;

[0022] Figure 3 This is a schematic diagram of the detection component of the present invention;

[0023] Figure 4 This is a cross-sectional structural schematic diagram of the mounting block, sleeve, support block and mounting shell of the present invention;

[0024] Figure 5 This is a partial structural schematic diagram of the sampling component of the present invention;

[0025] Figure 6 This is a schematic diagram of a partial connection of the connector of the present invention;

[0026] Figure 7 This is a schematic diagram of the structure of the additive assembly of the present invention;

[0027] Figure 8 This is a cross-sectional view of the support plate and the cylinder, and an exploded structural diagram of the receiving cylinder and the limiting base of the present invention;

[0028] Figure 9 This is a cross-sectional structural schematic diagram of the housing of the present invention;

[0029] Figure 10 This is a cross-sectional structural schematic diagram of the connecting shell of the present invention;

[0030] Figure 11 This is a schematic diagram of the sliding component connection structure of the present invention;

[0031] Figure 12 This is a partial cross-sectional structural diagram of the slider of the present invention.

[0032] In the diagram: 11. Instrument body; 12. Guide frame; 13. First guide rail; 14. Second guide rail; 15. Mounting component; 16. Sampling needle; 2. Detection assembly; 21. Mounting block; 22. Support block; 23. Sleeve; 24. First sample tube; 25. Mounting plate; 26. Mounting shell; 27. Photoelectric detection sensor; 28. Camera; 29. ​​Indicator light; 3. Sampling assembly; 31. First bracket; 32. Second bracket; 33. Second sample tube; 34. First pressure block; 35. Connector; 36. First switch; 4. Additive assembly; 41. Support plate; 42. Cylinder; 43. Connecting pipe; 44. Receiving cylinder; 45. Limiting base; 46. Pressure sensor; 47. Solenoid valve; 48. Housing; 49. First electromagnet; 410. Moving block; 411. First magnet; 412. First spring; 413. Pressing element; 414. Second electromagnet; 415. Sliding element; 416. Third electromagnet; 417. Connecting shell; 418. Fourth electromagnet; 419. Tooth block; 420. Second spring; 421. Toothed rod; 422. Slider; 423. Second magnet; 424. Third spring; 425. Second switch; 426. Second pressing block; 427. Third switch; 428. Third pressing block; 429. Fourth switch; 430. Distance sensor; 51. Centrifuge module; 52. Waste liquid box; 61. Magnetic stirring module. Detailed Implementation

[0033] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0034] Example 1

[0035] Please see Figures 1 to 12 The present invention provides a technical solution: a clinical platelet aggregation detection carrier, comprising: an instrument body 11, a guide frame 12 disposed on the inner side of the instrument body 11, a first guide rail 13 disposed on the guide frame 12, a second guide rail 14 disposed on the first guide rail 13, an installation component 15 disposed on the second guide rail 14, and a sampling needle 16 disposed on the installation component 15.

[0036] It also includes: detection component 2, which is located inside the instrument body 11. Detection component 2 is used to detect different types of blood samples such as lipemia, anemia and normal blood, and to select the blood sample centrifugation operation.

[0037] Sampling component 3 is located inside the instrument body 11. Sampling component 3 automatically adjusts to collect blood samples at different depths based on the lipid blood, anemia and normal blood samples detected by detection component 2.

[0038] Additive addition component 4 is located inside the instrument body 11. The additive addition component 4 automatically adjusts the amount of inducing agent added according to the sample volume taken by the sampling component 3.

[0039] When detecting platelet aggregation using the instrument body 11, the first guide rail 13 can be controlled to move left and right along the guide frame 12, the second guide rail 14 can be controlled to move back and forth along the first guide rail 13, and the mounting component 15 can be controlled to move up and down along the second guide rail 14, adjusting the position and sampling height of the sampling needle 16 (existing technology application). Through the detection component 2, different types of samples, including lipemia, anemia, and normal blood, can be detected. The system can automatically indicate whether blood centrifugation is necessary based on the sample type. For anemia samples, characterized by a reduced red blood cell count or decreased hemoglobin content, leading to a decreased hematocrit, whole blood or deep sampling is required to ensure the representativeness of the platelet count and maintain the physiological matrix environment. Centrifugation is unnecessary to prevent a significant reduction in the red blood cell layer volume and a relative thickening of the plasma layer caused by centrifugation, thus avoiding the negative effects of centrifugation. False negatives (misjudged as platelet dysfunction) or test failures caused by layer abnormalities can be addressed by using sampling component 3. Based on the lipid-rich, anemic, and normal blood samples detected by detection component 2, the system automatically adjusts the sampling depth of blood samples. For lipid-rich samples, which may exhibit false low aggregation, the upper chylous layer is discarded after centrifugation, and the intermediate clear PRP (platelet-rich plasma) layer is collected. For anemic samples, the sample is gently inverted and mixed to ensure uniform anticoagulant distribution, and the mixed whole blood is used for testing (deep sampling). For normal blood samples, the upper PRP layer is collected after centrifugation. The dosing component 4 automatically adjusts the amount of inducing agent added based on the sample volume collected by sampling component 3, ensuring that the concentration of the added inducing agent (the ratio of the added inducing agent mass to the total volume of the sample and inducing agent) reaches the specified range, thereby improving the accuracy of platelet aggregation detection.

[0040] The detection component 2 includes a mounting block 21 fixedly connected to the inner wall of the instrument body 11. A support block 22 fixedly connected to the bottom of the instrument body 11 is provided on the lower side of the mounting block 21. A sleeve 23 is fixedly connected to the lower side of the mounting block 21. A first sample tube 24 is provided inside the mounting block 21, the sleeve 23 and the support block 22. The through hole on the mounting block 21, the sleeve 23 and the groove on the upper side of the support block 22 are adapted to the first sample tube 24. A mounting plate 25 is fixedly connected to the lower side of the mounting block 21. A mounting shell 26 and a camera 28 are fixedly connected to one side of the mounting plate 25. A photoelectric detection sensor 27 is fixedly connected to the inner side of the mounting shell 26. The sleeve 23 is located at the position of the mounting shell 26 and is set as a through hole so that the photoelectric detection sensor 27 can detect the blood sample in the first sample tube 24. An indicator light 29 is provided on the upper side of the mounting block 21.

[0041] The first sample tube 24 containing the blood sample is placed inside the mounting block 21, sleeve 23, and support block 22. When detected by the photoelectric detection sensor 27, the photoelectric detection sensor 27 emits a light source and converts the transmitted light intensity into a current signal. For lipemic samples, the light transmittance is low and the output current signal is low. For anemic samples, the number of red blood cells is low, the light transmittance is high, and the output current signal is relatively high. For normal blood samples, the output current signal is between that of lipemic and anemic blood. The camera 28 captures images of the blood sample and extracts physical features (HSV color, GLCM texture, red blood cell layer height) from the images. Based on the labeled image library, it further detects and judges lipemic, anemic, and normal blood samples to improve detection accuracy. If the detected sample is lipemic or normal blood, the indicator light 29 will light up, indicating that the blood sample needs to be centrifuged. If the detected sample is anemic, the indicator light 29 will not light up, and whole blood or deep sampling will be taken after mixing without centrifugation.

[0042] The instrument body 11 is equipped with a centrifugation module 51 and a waste liquid box 52. When the indicator light 29 is lit, the first sample tube 24 is centrifuged through the centrifugation module 51. The waste liquid box 52 can be used to collect waste liquid, such as the upper chyle waste liquid discarded for lipemia samples.

[0043] The sampling assembly 3 includes a first bracket 31 and a second bracket 32 ​​fixedly connected to the inside of the instrument body 11. A second sample tube 33 is provided on the second bracket 32. A connector 35 is fixedly connected to one side of the second guide rail 14. Three first switches 36 are provided on the side of the connector 35 near the mounting part 15. A first pressure block 34 is fixedly connected to one side of the mounting part 15. The end face of the first pressure block 34 is arc-shaped to facilitate pressing the first switches 36.

[0044] After the first sample tube 24 is centrifuged by the centrifugation module 51, it is placed on the first support 31. When the sample is lipemic, the middle first switch 36 is turned on. When the mounting part 15 moves down and drives the first pressure block 34 to move synchronously, when the first pressure block 34 moves down to touch the middle first switch 36, the mounting part 15 stops moving down. At this time, the middle layer of clear PRP can be aspirated through the sampling needle 16. If the sample is anemic, the lower first switch 36 is turned on for deep sampling. If the sample is normal blood, the upper first switch 36 is turned on to collect the upper layer of PRP. The collected sample is then transferred to the second sample tube 33.

[0045] Example 2

[0046] The dosing assembly 4 includes a support plate 41 fixedly connected to the inner wall of the instrument body 11. A cylinder 42 is fixedly connected to the support plate 41. The cylinder 42 stores an inducing agent. A connecting pipe 43 is fixedly connected to the lower side of the cylinder 42. A solenoid valve 47 is installed on the connecting pipe 43. A receiving cylinder 44 is provided on the lower side of the connecting pipe 43. A limiting base 45 is provided on the lower side of the receiving cylinder 44. The receiving cylinder 44 is limited to the upper side of the limiting base 45. The limiting base 45 is fixedly connected to the inner bottom of the instrument body 11. A pressure sensor 46 is provided on the limiting base 45. The receiving cylinder 44 abuts against the upper side of the pressure sensor 46.

[0047] A second pressure block 426 is fixedly connected to the inner side of the first guide rail 13. A third switch 427 is provided on the inner wall of the instrument body 11. A fourth switch 429 is provided on the upper side of the first guide rail 13. A third pressure block 428 is fixedly connected to one side of the second guide rail 14. The end faces of the second pressure block 426 and the third pressure block 428 are both set to arc shape, which can facilitate the contact of the third switch 427 and the fourth switch 429.

[0048] A housing 48 is fixedly connected to the upper side of the support plate 41. A second electromagnet 414 is fixedly connected to the inner side of the housing 48. A sliding member 415 is slidably arranged at the bottom inner side of the housing 48. A first limiting groove adapted to the sliding member 415 is provided at the bottom inner side of the housing 48. The sliding member 415 is slidably arranged along the first limiting groove, which can guide and limit the movement of the sliding member 415. A third electromagnet 416 that repels the second electromagnet 414 is fixedly connected to one side of the sliding member 415. A distance sensor 430 is provided on one side of the mounting part 15. The distance sensor 430 is electrically connected to the second electromagnet 414 and the third electromagnet 416.

[0049] Initially, the distance sensor 430 is electrically connected to the second electromagnet 414, and the third electromagnet 416 is energized but not electrically connected to the distance sensor 430. After the sample is transferred to the second sample tube 33 by the sampling needle 16, and after the control mounting component 15 moves upward along the second guide rail 14, the distance sensor 430 can detect the sample liquid level in the second sample tube 33. When the detected sample liquid level is high, the sample volume in the second sample tube 33 is large, which will enhance the output signal of the distance sensor 430, making the magnetism of the second electromagnet 414 relatively strong, and the repulsive effect on the third electromagnet 416 relatively strong. This causes the sliding component 415 to move a relatively large distance away from the second electromagnet 414, and the third spring 424 is compressed.

[0050] A connecting shell 417 is fixedly connected to one side of the sliding member 415. A fourth electromagnet 418 is fixedly connected to the inside of the connecting shell 417. A toothed block 419 that attracts the fourth electromagnet 418 is slidably arranged inside the connecting shell 417. A second spring 420 that is fixedly connected to the connecting shell 417 is symmetrically fixedly connected to the inside of the toothed block 419. A toothed rod 421 is fixedly connected to the inside of the housing 48. The toothed rod 421 is located on one side of the connecting shell 417 and cooperates with the toothed block 419.

[0051] Initially, the fourth electromagnet 418 is energized, generating an attraction to the toothed block 419, causing the toothed block 419 to disengage from the toothed rod 421. The second spring 420 is compressed to avoid hindering the movement of the slider 415. After the distance sensor 430 detects the liquid level in the second sample tube 33, the fourth electromagnet 418 is de-energized. Under the elastic force of the second spring 420, the toothed block 419 is engaged and fixed with the toothed rod 421, maintaining the current position of the slider 415.

[0052] A slider 422 is slidably disposed on the upper side of the slider 415. Correspondingly, a second limiting groove adapted to the slider 422 is disposed on the upper side of the slider 415. The slider 422 is slidably disposed along the second limiting groove. A third spring 424 fixedly connected to the inner wall of the housing 48 is fixedly connected to one side of the slider 422. A second magnet 423 repelling the third electromagnet 416 is fixedly connected to the other side of the slider 422. A second switch 425 is disposed on one side of the slider 422.

[0053] After detecting the liquid level in the second sample tube 33 using the distance sensor 430, the movement of the first guide rail 13 along the guide frame 12 is controlled. When the second pressure block 426 contacts the third switch 427, the movement stops. The second guide rail 14 is then controlled to move along the first guide rail 13, stopping when the third pressure block 428 contacts the fourth switch 429. At this point, the distance sensor 430 corresponds vertically to the receiving cylinder 44. The distance sensor 430 can detect the level of the inducing agent added to the receiving cylinder 44. The movement of the third switch 427 and the fourth switch 429 is then controlled. When there is resistance, the distance sensor 430 can be electrically connected to the third electromagnet 416; by controlling the opening of the solenoid valve 47, the inducer in the cylinder 42 can enter the receiving cylinder 44 through the connecting pipe 43. By detecting the liquid level of the inducer in the receiving cylinder 44 through the distance sensor 430, the repulsive force of the third electromagnet 416 on the second magnet 423 can be gradually increased, causing the slider 422 to move away from the third electromagnet 416. The total distance that the slider 422 moves away from the second electromagnet 414 represents the total volume of the sample and inducer added.

[0054] A first electromagnet 49 is fixedly connected to the inside of the housing 48. The first electromagnet 49 is electrically connected to the pressure sensor 46. A moving block 410 is slidably arranged inside the housing 48. A third limiting groove adapted to the moving block 410 is provided at the bottom of the inside of the housing 48. The moving block 410 is slidably arranged along the third limiting groove. A first spring 412 fixedly connected to the inner wall of the housing 48 is fixedly connected to one side of the moving block 410. A first magnet 411 repelling the first electromagnet 49 is fixedly connected to the other side of the moving block 410. A pressing member 413 is fixedly connected to one side of the moving block 410. The two ends of the pressing member 413 are set with arc-shaped end faces to facilitate contact with the second switch 425. A magnetic stirring module 61 is provided inside the instrument body 11.

[0055] As the inducer is added into the receiving cylinder 44, the pressure sensor 46 detects the weight of the added inducer, causing the magnetism of the first electromagnet 49 to gradually increase. This gradually increases the repulsive force on the first magnet 411, causing the moving block 410 to move further away from the first electromagnet 49. The first spring 412 is compressed. The distance the moving block 410 moves away from the first electromagnet 49 indicates the mass of the added inducer. When the pressing member 413 moves to contact the second switch 425, it indicates that after adding the inducer currently in the receiving cylinder 44, the concentration of the added and mixed inducer (the mass of the inducer) will increase. When the ratio of the added inducer mass to the total volume of the sample and the added inducer reaches the specified range, that is, the final concentration of the inducer reaches about 1 μM, the solenoid valve 47 will be closed. By controlling the descent of the sampling needle 16, the inducer in the receiving tube 44 is drawn up and added to the second sample tube 33 to mix with the sample. The magnetic stirring module 61 can magnetically stir the sample and the inducer to achieve uniform mixing, thereby detecting the degree of platelet aggregation. The addition component 4 automatically adjusts the amount of inducer added according to the sample volume, which can improve the accuracy of platelet aggregation detection.

[0056] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0057] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A clinical platelet aggregation detection vector, comprising: The instrument body has a guide frame inside, a first guide rail on the guide frame, a second guide rail on the first guide rail, a mounting component on the second guide rail, and a sampling needle on the mounting component. Its features include: a detection component, which is disposed inside the instrument body and is used to detect different types of blood samples, such as lipemia, anemia, and normal blood, and to select for centrifugation of blood samples; The sampling component is located inside the instrument body. The sampling component automatically adjusts to collect blood samples at different depths based on the lipid blood, anemia, and normal blood samples detected by the detection component. The dosing component is located inside the instrument body and automatically adjusts the amount of inducing agent added based on the sample volume collected by the sampling component.

2. The clinical platelet aggregation detection carrier according to claim 1, characterized in that: The detection component includes a mounting block fixedly connected to the inner wall of the instrument body. A support block fixedly connected to the bottom of the instrument body is provided on the lower side of the mounting block. A sleeve is fixedly connected to the lower side of the mounting block. A first sample tube is provided inside the mounting block, sleeve, and support block. A mounting plate is fixedly connected to the lower side of the mounting block. A mounting shell and a camera are fixedly connected to one side of the mounting plate. A photoelectric detection sensor is fixedly connected inside the mounting shell. An indicator light is provided on the upper side of the mounting block.

3. The clinical platelet aggregation detection carrier according to claim 1, characterized in that: The instrument body is equipped with a centrifugation module and a waste liquid box on its inner side.

4. The clinical platelet aggregation detection carrier according to claim 1, characterized in that: The sampling assembly includes a first bracket and a second bracket fixedly connected to the inside of the instrument body. A second sample tube is provided on the second bracket. A connector is fixedly connected to one side of the second guide rail. Three first switches are provided on the side of the connector near the mounting component. A first pressure block is fixedly connected to one side of the mounting component.

5. The clinical platelet aggregation detection carrier according to claim 1, characterized in that: The dosing assembly includes a support plate fixedly connected to the inner wall of the instrument body, a cylinder fixedly connected to the support plate, a connecting pipe fixedly connected to the lower side of the cylinder, a solenoid valve installed on the connecting pipe, a receiving cylinder provided on the lower side of the connecting pipe, a limit base provided on the lower side of the receiving cylinder, the limit base fixedly connected to the inner bottom of the instrument body, and a pressure sensor provided on the limit base.

6. The clinical platelet aggregation detection carrier according to claim 5, characterized in that: A second pressure block is fixedly connected to the inner side of the first guide rail, a third switch is provided on the inner wall of the instrument body, a fourth switch is provided on the upper side of the first guide rail, and a third pressure block is fixedly connected to one side of the second guide rail.

7. The clinical platelet aggregation detection carrier according to claim 5, characterized in that: A housing is fixedly connected to the upper side of the support plate, a second electromagnet is fixedly connected to the inner side of the housing, a sliding member is slidably arranged at the bottom of the inner side of the housing, a third electromagnet that repels the second electromagnet is fixedly connected to one side of the sliding member, and a distance sensor is arranged on one side of the mounting component.

8. The clinical platelet aggregation detection carrier according to claim 7, characterized in that: A connecting shell is fixedly connected to one side of the sliding member, a fourth electromagnet is fixedly connected to the inside of the connecting shell, a toothed block that attracts the fourth electromagnet is slidably arranged inside the connecting shell, a second spring that is fixedly connected to the connecting shell is symmetrically fixed to the inside of the toothed block, and a toothed rod is fixedly connected to the inside of the shell, the toothed rod is located on one side of the connecting shell, and the toothed rod cooperates with the toothed block.

9. The clinical platelet aggregation detection carrier according to claim 7, characterized in that: A slider is slidably mounted on the upper side of the slider. A third spring is fixedly connected to one side of the slider and fixedly connected to the inner wall of the housing. A second magnet that repels the third electromagnet is fixedly connected to the other side of the slider. A second switch is provided on one side of the slider.

10. The clinical platelet aggregation detection carrier according to claim 7, characterized in that: A first electromagnet is fixedly connected to the inner side of the housing, a movable block is slidably arranged on the inner side of the housing, a first spring is fixedly connected to one side of the movable block and fixedly connected to the inner wall of the housing, a first magnet that repels the first electromagnet is fixedly connected to the other side of the movable block, a pressing member is fixedly connected to one side of the movable block, and a magnetic stirring module is arranged on the inner side of the instrument body.

Images