Analyzer for simultaneous detection of multiple items

Abstract

The application discloses an analyzer for simultaneously detecting multiple items. The analyzer comprises a machine body, a microfluidic detection chip and a detection assembly. The microfluidic detection chip is rotatably and replaceably arranged in the machine body, and the microfluidic detection chip has a plurality of detection grooves, each of which contains a detection reagent for different detection items. The detection assembly is arranged in the machine body, and the detection assembly comprises a light emitting component and a receiving component. The light emitting component comprises a plurality of light sources, each of which emits light of different wavelength. During the rotation of the microfluidic detection chip, each detection groove passes through each light source in turn along the rotation direction of the microfluidic detection chip. When the detection groove corresponds to the light source, the light source emits a light signal to the detection groove, and the receiving component is used for receiving the light signal emitted by the detection groove. The analyzer of the application can at least solve the problem that the operation process of the analyzer in the prior art is relatively complex when different items of blood are detected.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and more specifically, to an analyzer for simultaneously detecting multiple items. Background Technology

[0002] In related technologies, analyzers are typically equipped with different microfluidic detection chips to perform single-item tests on samples, such as biochemistry, immunology, and coagulation. However, existing analyzers have relatively complex operating procedures when performing different tests on blood. Summary of the Invention

[0003] The main objective of this application is to provide an analyzer for simultaneously detecting multiple items, thereby solving the problem of complex operation procedures in existing analyzers when performing different tests on blood.

[0004] According to one aspect of this application, an analyzer for simultaneously detecting multiple items is provided, comprising: Organism; A microfluidic detection chip is rotatably and replaceably disposed in the body. The microfluidic detection chip has multiple detection slots, and each detection slot contains detection reagents for different detection items. A detection component is disposed on the body. The detection component includes a light-emitting component and a receiving component. The light-emitting component includes multiple light sources, each of which emits a different wavelength. During the rotation of the microfluidic detection chip, each detection slot passes sequentially through each light source along the rotation direction of the microfluidic detection chip; when a detection slot corresponds to a light source, the light source emits a light signal to the detection slot, and the receiving component is used to receive the light signal emitted from the detection slot.

[0005] Furthermore, the light-emitting component also includes a first support portion, on which the light source is disposed. The first support portion has a plurality of first channels extending along the height direction of the body, and the light source is disposed in each of the first channels in a corresponding manner. During the rotation of the microfluidic detection chip, each detection slot passes through each of the first channels in sequence along the rotation direction of the microfluidic detection chip. When the detection slot corresponds to the first channel, the light source emits a light signal to the detection slot through the first channel.

[0006] Furthermore, the first channel includes a first branch channel and a second branch channel that are interconnected, the cross-section of the first branch channel is larger than the cross-section of the second branch channel, and the light source is disposed in the first branch channel.

[0007] Furthermore, the body is also provided with a first base, and the microfluidic detection chip is disposed on the first base. The first base has a plurality of second channels extending along the height direction of the body, and the second channels are arranged one-to-one with the first channels. During the rotation of the microfluidic detection chip, each detection groove passes through each of the second channels in sequence along the rotation direction of the microfluidic detection chip. When the detection groove corresponds to the second channel, the light source emits a light signal to the detection groove through the second channel.

[0008] Furthermore, the body is also provided with a dustproof component, which is located between the first base and the bottom of the microfluidic detection chip, and the dustproof component covers the end of the second channel away from the first channel.

[0009] Furthermore, the dustproof component includes a light-transmitting element, and the light-transmitting element comprises multiple elements, each of which is disposed in a corresponding manner at the end of the second channel away from the first channel.

[0010] Furthermore, the dustproof component also includes a dustproof element located on the side of the light-transmitting element close to the microfluidic detection chip, and the dustproof element has multiple clearance holes, which are arranged one-to-one with the multiple light-transmitting elements.

[0011] Furthermore, the receiving component includes a second support portion and a receiving plate. The second support portion is disposed on the body and has a plurality of third channels extending along the height direction of the body. The third channels are arranged one-to-one with the light source. The receiving plate is disposed on the second support portion and covers the third channels. When the detection slot corresponds to the light source, the light source emits a light signal to the detection slot, and the receiving board receives the light signal emitted from the detection slot through the third channel.

[0012] Furthermore, a second base is provided on the body, and the second support is disposed on the second base. The second base has an installation space and a plurality of fourth channels extending along the height direction of the body. The fourth channels are arranged in a one-to-one correspondence with the third channels. The microfluidic detection chip is rotatably and detachably disposed in the installation space; and / or, A filter is provided in the third channel and / or the fourth channel.

[0013] Furthermore, the light-emitting component and the receiving component are located on opposite sides of the microfluidic detection chip along the height direction of the body, and the microfluidic detection chip includes a transparent microfluidic detection chip.

[0014] In this application, since each light source emits a different wavelength, when one detection cell corresponds to one light source, that light source emits a light signal to the blood sample and reagent mixture within the detection cell. Simultaneously, the receiving component in the detection assembly activates, capturing in real-time the feedback light signal emitted by the mixture after being excited by light. Changes in the light signal are then analyzed to determine the detection parameters for the corresponding test item in the sample. The entire detection process eliminates the need for multiple disassemblies, replacements, or adjustments to the microfluidic detection chip, as well as switching detection modes, adjusting light source parameters, or intervening in the detection process. Simply rotating the microfluidic detection chip allows each detection cell carrying the blood sample and corresponding reagent to sequentially align with a light source of the appropriate wavelength. The light signal emitted by the light source acts on the detection cell, and the receiving component simultaneously receives the feedback light signal, thus enabling continuous automatic detection of multiple test items. This eliminates the need for complex switching between different test items, simplifying the overall operation of multi-item blood testing. Attached Figure Description

[0015] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, are illustrative and descriptive of this application and are used to explain this application, but do not constitute an undue limitation of this application. In the drawings: Figure 1 This is a diagram showing the connection relationships of the various components of the analyzer disclosed in the embodiments of this application; Figure 2 This is a partial cross-sectional view of the analyzer disclosed in the embodiments of this application; Figure 3 This is a schematic diagram of the receiving component disclosed in an embodiment of this application; Figure 4 This is a schematic diagram of the structure of the microfluidic detection chip disclosed in the embodiments of this application; Figure 5 This is a schematic diagram of the structure of the dustproof component disclosed in the embodiments of this application; Figure 6 The embodiments disclosed in this application Figure 5 Enlarged view of region A in the middle; Figure 7 This is a schematic diagram of the structure of the organism disclosed in the embodiments of this application.

[0016] The above figures include the following reference numerals: 10. Body; 20. Microfluidic detection chip; 21. Detection groove; 30. Detection component; 31. Light-emitting component; 311. Light source; 312. First support part; 313. First channel; 3131. First branch channel; 3132. Second branch channel; 32. Receiving component; 321. Second support part; 322. Receiving plate; 323. Third channel; 40. First base; 41. Second channel; 50. Dustproof component; 51. Light-transmitting component; 52. Dustproof component; 53. Clearance hole; 60. Second base; 61. Installation space; 62. Fourth channel; 70. Filter; 80. Drive motor. Detailed Implementation

[0017] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. This application will now be described in detail with reference to the accompanying drawings and embodiments.

[0018] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0019] Unless otherwise specifically stated, the relative arrangement, numerical expressions, and values ​​of the components and steps described in these embodiments do not limit the scope of this application. It should also be understood that, for ease of description, the dimensions of the various parts shown in the drawings are not drawn to actual scale. Techniques, methods, and devices known to those skilled in the art may not be discussed in detail, but where appropriate, such techniques, methods, and devices should be considered part of the specification. In all examples shown and discussed herein, any specific values ​​should be interpreted as merely exemplary and not as limitations. Therefore, other examples of exemplary embodiments may have different values. It should be noted that similar reference numerals and letters in the following drawings denote similar items; therefore, once an item is defined in one drawing, it need not be further discussed in subsequent drawings.

[0020] As described in the background section, in related technologies, analyzers are typically equipped with different microfluidic detection chips to perform single-item tests on samples, such as biochemistry, immunology, and coagulation. However, existing analyzers require changing to microfluidic chips adapted to different items when performing different tests on blood, making the operation process relatively complex. Therefore, this application provides a new analyzer for simultaneously detecting multiple items. This analyzer at least solves the problem of the complex operation process of existing analyzers when performing different tests on blood. The analyzer of this application will be described in detail below with reference to the accompanying drawings.

[0021] It is worth mentioning that the analyzer of this application can simultaneously detect biochemical, immunological, and coagulation parameters. The biochemical parameters include potassium ions, sodium ions, chloride ions, base excess, blood glucose, lactate, blood urea nitrogen, creatine kinase, and hemoglobin in the sample. The immunological parameters include C-reactive protein and atrial natriuretic peptide in the sample. The coagulation parameters include prothrombin time, fibrinogen, activated partial thromboplastin time, and D-dimer in the sample.

[0022] It should be noted that "the height direction of the body 10" in this application refers to Figure 2 The direction indicated by the middle arrow X.

[0023] See Figures 1 to 7 As shown in the figure, this application provides an analyzer for simultaneously detecting multiple items, hereinafter referred to as the analyzer. The analyzer includes a body 10, a microfluidic detection chip 20, and a detection component 30.

[0024] Specifically, the microfluidic detection chip 20 is rotatably and replaceably mounted on the body 10. The microfluidic detection chip 20 has multiple detection slots 21, each containing a detection reagent for different detection items. The detection component 30 is mounted on the body 10 and includes a light-emitting component 31 and a receiving component 32. The light-emitting component 31 includes multiple light sources 311, each emitting a different wavelength. During the rotation of the microfluidic detection chip 20, each detection slot 21 passes sequentially through each light source 311 along the rotation direction of the microfluidic detection chip 20. When a detection slot 21 corresponds to a light source 311, the light source 311 emits a light signal to the detection slot 21, and the receiving component 32 receives the light signal emitted from the detection slot 21.

[0025] It should be noted that the testing reagents in this application refer to specialized testing reagents for biochemical, immunological, and coagulation tests; the wavelength emitted by the light source 311 in this application corresponds to the testing requirements of different types of biochemical, immunological, and coagulation tests. In some embodiments, the light source 311 includes an LED lamp.

[0026] It should be noted that the phrase "each detection slot 21 passes through each light source 311 sequentially along the rotation direction of the microfluidic detection chip 20" in this application means that during the rotation of the microfluidic detection chip 20, the first detection slot 21 will rotate first to correspond with the first light source 311, completing the precise docking between the two; after the microfluidic detection chip 20 continues to rotate a certain angle, the first detection slot 21 will leave the area of ​​the first light source 311 and gradually rotate to correspond with the second light source 311. At the same time, the second detection slot 21 will rotate synchronously to correspond with the first light source 311, and so on. That is to say, the first detection slot 21 will sequentially complete the docking with the first light source 311, the second light source 311, ... up to the Nth light source 311 (N is the total number of light sources 311), and each subsequent detection slot 21 will pass through each light source 311 sequentially along the rotation direction of the microfluidic detection chip 20 in the same order as the first detection slot 21, achieving precise correspondence.

[0027] When using the analyzer to perform biochemical, immunological, and coagulation tests, the operator first needs to install the compatible microfluidic detection chip 20 on the main unit 10. Then, the analyzer is started, allowing the blood sample to be thoroughly mixed with the pre-loaded test reagents in each detection slot 21. The microfluidic detection chip 20 is then rotated. During this rotation, the multiple detection slots 21 on the microfluidic detection chip 20 sequentially pass through the various light sources 311 in the detection assembly 30, and each light source 311 emits a light signal to its respective detection slot 21. Since each light source 311 emits a different wavelength, when one detection slot 21 corresponds to one of the light sources 311, that light source 311 emits a light signal to the blood sample and reagent mixture within the detection slot 21. Simultaneously, the receiving component 32 in the detection assembly 30 is activated, capturing in real-time the feedback light signal emitted by the light-excited mixture within the detection slot 21. The changes in the light signal are then analyzed to determine the corresponding test parameters in the sample. The entire detection process does not require multiple disassembly, replacement, or adjustment of the microfluidic detection chip 20, nor does it require switching detection modes, adjusting the parameters of the light source 311, or intervening in the detection process. Simply by rotating the microfluidic detection chip 20, each detection slot 21 carrying a blood sample and corresponding reagent can be sequentially aligned with the light source 311 of the appropriate wavelength. After the light signal emitted by the light source 311 acts on the detection slot 21, the receiving component 32 synchronously receives the feedback light signal, thereby realizing continuous automatic detection of multiple detection items without the need for complex operation switching between different detection items, simplifying the overall operation process of multi-item blood testing.

[0028] It is worth mentioning that, since the wavelengths emitted by each light source 311 are different, and the mixture in each detection cell 21 corresponds to a specific detection item (biochemical, immunological, or coagulation item), although the mixture can produce a specific response to the light signal of the appropriate wavelength to output accurate detection parameters, the detection cell 21 will pass through each light source 311 in sequence as the microfluidic detection chip 20 rotates. At this time, each light source 311 will emit a light signal to the detection cell 21 it passes through. When the wavelength of the emitted light signal does not match the mixture in the detection cell 21, the mixture can still be effectively excited by the light signal of that wavelength and generate a feedback light signal. However, the intensity and wavelength characteristics of this feedback light signal are significantly different from the signal generated by the appropriate wavelength, and cannot accurately reflect the true detection result of the item corresponding to the detection cell 21. After the receiving component 32 captures this kind of non-specific feedback light signal, it will not be converted into valid detection data because the signal does not meet the preset detection standard. Moreover, this kind of invalid light signal will not damage the mixture itself, nor will it interfere with the subsequent excitation and detection of the detection cell 21 by the appropriate wavelength light source 311.

[0029] Optionally, the detection slots 21 in this application can be set to two, three, or more, and this application does not make a specific limitation. Similarly, the light source 311 can be set to two, three, or more, and this application does not make a specific limitation.

[0030] like Figure 2 and Figure 7 As shown, in some embodiments, the light-emitting component 31 further includes a first support portion 312, and a light source 311 is disposed on the first support portion 312. The first support portion 312 has a plurality of first channels 313 extending along the height direction of the body 10, and the light sources 311 are disposed one-to-one in the first channels 313. During the rotation of the microfluidic detection chip 20, each detection slot 21 passes through each first channel 313 sequentially along the rotation direction of the microfluidic detection chip 20. When the detection slot 21 corresponds to the first channel 313, the light source 311 emits a light signal to the detection slot 21 through the first channel 313. Optionally, the number of first channels 313 in this application can be set to two, three or more, and this application does not make a specific limitation.

[0031] Specifically, in this embodiment, the first support 312 provides stable mounting and positioning for each light source 311, preventing the light source 311 from shifting and affecting the detection accuracy. Since the light sources 311 are arranged one-to-one in the first channel 313, when the light source 311 emits a light signal to the detection slot 21, each first channel 313 can separate each light source 311, preventing mutual interference between the light signals of different light sources 311 and ensuring that the light signals emitted by each light source 311 are pure and accurate. Understandably, during the rotation of the microfluidic detection chip 20, the multiple detection slots 21 on the microfluidic detection chip 20 will sequentially pass through each first channel 313 along the rotation direction. When a certain detection slot 21 is aligned with the corresponding first channel 313, the light source 311 set in that channel will emit a light signal to the blood sample and reagent mixture in the detection slot 21 through the first channel 313. The first channel 313 can guide and converge the light signal, reduce the diffusion loss of the light signal during transmission, and allow the light signal to act more concentratedly on the detection slot 21, thereby enabling the receiving component 32 to capture the feedback light signal more clearly and accurately.

[0032] like Figure 2 As shown, in some embodiments, the first channel 313 includes a first branch channel 3131 and a second branch channel 3132 that are interconnected. The cross-section of the first branch channel 3131 is larger than the cross-section of the second branch channel 3132, and the light source 311 is disposed within the first branch channel 3131. It should be noted that, in this application, "the cross-section of the first branch channel 3131" refers to the cross-section obtained by cutting the first branch channel 3131 along a direction perpendicular to its length; similarly, "the cross-section of the second branch channel 3132" refers to the cross-section obtained by cutting the second branch channel 3132 along a direction perpendicular to its length.

[0033] Understandably, when the light source 311 emits a light signal within the first channel 3131, the larger cross-section of the first channel 3131 provides a stable accommodating space for the light source 311. Simultaneously, it facilitates the full diffusion and convergence of the emitted light signal to the connected second channel 3132, preventing scattering of the light signal due to space constraints in the initial stages of emission. The smaller cross-section of the second channel 3132, on the other hand, provides precise guidance and convergence for the light signal, further focusing the light signal transmitted from the first channel 3131, reducing signal loss and diffusion during transmission, and allowing the light signal to act more concentratedly and precisely on the detection slot 21 that has rotated to the corresponding position in the channel.

[0034] like Figure 2 , Figures 5 to 6As shown, in some embodiments, a first base 40 is also provided on the body 10, and the microfluidic detection chip 20 is disposed on the first base 40. The first base 40 has multiple second channels 41 extending along the height direction of the body 10, and the second channels 41 are arranged one-to-one with the first channels 313. During the rotation of the microfluidic detection chip 20, each detection slot 21 passes through each second channel 41 sequentially along the rotation direction of the microfluidic detection chip 20. When the detection slot 21 corresponds to the second channel 41, the light source 311 emits a light signal to the detection slot 21 through the second channel 41. It can be understood that the first base 40 in this embodiment provides a stable mounting base for the microfluidic detection chip 20, ensuring that the microfluidic detection chip 20 will not shift or shake during rotation, thus ensuring the stability of the detection process.

[0035] Specifically, during the rotation of the microfluidic detection chip 20, each detection slot 21 on the microfluidic detection chip 20 sequentially passes through each second channel 41 along the rotation direction. When a detection slot 21 rotates to correspond with a certain second channel 41, that second channel 41 forms a continuous optical transmission path with the corresponding first channel 313. The optical signal emitted by the light source 311 through the first channel 313 can be accurately transmitted to the detection slot 21 through the corresponding connected second channel 41. The second channel 41 can further concentrate the optical signal, reduce the diffusion loss of the optical signal during transmission, and block external stray light interference, ensuring that the optical signal accurately acts on the mixture in the detection slot 21. At the same time, the second channel 41 is set in a one-to-one correspondence with the first channel 313. This correspondence matches the correspondence between the light source 311 and the detection slot 21, ensuring that each detection slot 21 can accurately connect with the light source 311 of the appropriate wavelength through the corresponding channel during rotation, without the need for manual adjustment of the channel position, effectively ensuring the accuracy and stability of the optical signal transmission.

[0036] like Figure 2 , Figures 5 to 6 As shown, in some embodiments, the body 10 is also provided with a dustproof component 50, which is located between the first base 40 and the bottom of the microfluidic detection chip 20, and the dustproof component 50 covers the end of the second channel 41 away from the first channel 313.

[0037] Specifically, the second channel 41 serves as a crucial path for the light signal to travel from the first channel 313 to the detection slot 21. Its end furthest from the first channel 313 directly corresponds to the detection slot 21 of the microfluidic detection chip 20, making it the necessary path for the light signal to enter the detection slot 21. It is also a weak point where dust and other impurities can easily enter the channel. In this embodiment, the dustproof component 50 covers the end of the second channel 41 furthest from the first channel 313, effectively preventing external dust and other impurities from entering the interior of the second channel 41. This avoids impurities adhering to the inner wall of the second channel 41 and affecting the light signal transmission, thereby preventing stray light interference or increased light signal loss. This ensures that the light signal emitted by the light source 311 can be accurately transmitted to the detection slot 21 via the first channel 313 and the second channel 41, effectively guaranteeing the accuracy of the detection results.

[0038] like Figure 2 and Figure 5 As shown, in some embodiments, the dustproof component 50 includes a light-transmitting element 51, and there are multiple light-transmitting elements 51, which are disposed one-to-one at the end of the second channel 41 away from the first channel 313. In some embodiments, the light-transmitting element 51 includes a glass sheet.

[0039] Specifically, in this embodiment, by installing the light-transmitting element 51 at the end of the second channel 41 away from the first channel 313, it can not only cover the ports of each second channel 41 and effectively block external dust and other impurities from entering the interior of the second channel 41, but also, by utilizing the light-transmitting characteristics of the light-transmitting element 51 itself, accurately transmit the light signal emitted by the light source 311 to the detection slot 21 through the first channel 313, the second channel 41 and the light-transmitting element 51, thereby achieving lossless and stray light interference-free light signal transmission.

[0040] Optionally, the light-transmitting element 51 in this application may be set to two, three or more, and this application does not make a specific limitation.

[0041] like Figure 2 and Figure 5 As shown, in some embodiments, the dustproof component 50 further includes a dustproof element 52, which is located on the side of the light-transmitting element 51 near the microfluidic detection chip 20. The dustproof element 52 has multiple clearance holes 53, which are arranged one-to-one with the multiple light-transmitting elements 51. In this embodiment, the dustproof element 52 is installed on the side of the light-transmitting element 51 near the microfluidic detection chip 20, which can further block external dust and other impurities, preventing them from entering the channel through the gap between the light-transmitting element 51 and the second channel 41, thereby ensuring that the surface of the light-transmitting element 51 is clean and does not affect the penetration and transmission of the light signal. The one-to-one arrangement of the multiple clearance holes 53 with the multiple light-transmitting elements 51 will not block the light-transmitting element 51, effectively ensuring that the light signal emitted by the light source 311 is accurately transmitted to the detection slot 21 through the first channel 313, the second channel 41, the light-transmitting element 51, and the clearance holes 53.

[0042] Optionally, the clearance holes 53 in this application may be two, three, or more; this application does not impose a specific limitation. Figure 5 The diagram shows the case where the clearance holes 53 are set to eight.

[0043] like Figures 2 to 3 As shown, in some embodiments, the receiving component 32 includes a second support portion 321 and a receiving plate 322. The second support portion 321 is disposed on the body 10 and has multiple third channels 323 extending along the height direction of the body 10. The third channels 323 are arranged one-to-one with the light source 311. The receiving plate 322 is disposed on the second support portion 321 and covers the third channels 323. When the detection slot 21 corresponds to the light source 311, the light source 311 emits a light signal to the detection slot 21, and the receiving plate 322 receives the light signal emitted from the detection slot 21 through the third channels 323. It can be understood that the second support portion 321 provides a stable mounting base for the receiving plate 322, ensuring that the receiving plate 322 will not shift during the entire detection process, thus ensuring the accuracy of light signal reception.

[0044] Specifically, when the microfluidic detection chip 20 rotates to align a detection slot 21 with the corresponding light source 311, the light source 311 emits a light signal into the mixture within the detection slot 21. The mixture, excited by the light, emits a feedback light signal. At this point, the third channel 323 corresponding to the light source 311 becomes the critical path for transmitting the feedback light signal to the receiving board 322. The feedback light signal can be accurately transmitted to the receiving board 322 through the third channel 323. The receiving board 322 captures the light signal and converts it into valid detection data. In this embodiment, the third channel 323 is configured in a one-to-one correspondence with the light source 311, ensuring that the feedback light signal generated by each light source 311 can be accurately received by the receiving board 322 through the corresponding third channel 323, thus avoiding interference between light signals from different detection items.

[0045] like Figures 2 to 3 As shown, in some embodiments, a second base 60 is provided on the body 10, and a second support 321 is provided on the second base 60. The second base 60 has an installation space 61 and a plurality of fourth channels 62 extending along the height direction of the body 10. The fourth channels 62 are provided in a one-to-one correspondence with the third channels 323. The microfluidic detection chip 20 is rotatably and detachably provided in the installation space 61.

[0046] Specifically, the second base 60 provides a stable mounting carrier for the second support 321 of the receiving component 32, ensuring that the second support 321 and its receiving board 322 and third channel 323 are fixed in position during the detection process, avoiding the impact of component displacement on the accurate reception of optical signals. At the same time, the mounting space 61 of the second base 60 provides a suitable placement area for the microfluidic detection chip 20. The microfluidic detection chip 20 is rotatably and detachably set in the mounting space 61, which not only ensures that the chip can rotate smoothly and at a uniform speed during detection, allowing each detection slot 21 to pass through the corresponding light source 311 in sequence to achieve continuous detection of multiple items, but also facilitates the replacement operation of the chip before and after detection, and the chip can be disassembled and assembled without complicated steps.

[0047] Understandably, when the detection tank 21 corresponds to the light source 311 and the light source 311 emits a light signal to excite the mixed liquid to generate a feedback light signal, the feedback light signal will be accurately transmitted to the receiving board 322 through the fourth channel 62 and the third channel 323 in sequence. The corresponding design of the fourth channel 62 and the third channel 323 further optimizes the transmission path of the light signal, reduces the diffusion and stray light interference of the feedback light signal during transmission, and ensures that the receiving board 322 can clearly capture the effective light signal.

[0048] Optionally, the fourth channel 62 in this application can be set to two, three or more, and this application does not make a specific limitation.

[0049] In some embodiments, a filter 70 is provided in the third channel 323 and / or the fourth channel 62. That is, in this embodiment, the filter 70 may be provided only in the third channel 323 and not in the fourth channel 62; or the filter 70 may be provided only in the fourth channel 62 and not in the third channel 323; or the filter 70 may be provided in both the third channel 323 and the fourth channel 62. It is understood that the filter 70 is used to prevent light other than the light signal emitted from the detection slot 21 from entering the third channel 323 and the fourth channel 62, and to avoid astigmatism or other interfering light from affecting the detection results of the analyzer.

[0050] like Figure 2As shown, in some embodiments, the light-emitting component 31 and the receiving component 32 are located on opposite sides of the microfluidic detection chip 20 along the height direction of the body 10, and the microfluidic detection chip 20 includes a transparent microfluidic detection chip. It can be understood that in this embodiment, the light-emitting component 31 may be located below the microfluidic detection chip 20, and the receiving component 32 may be located above the microfluidic detection chip 20; alternatively, the light-emitting component 31 may be located above the microfluidic detection chip 20, and the receiving component 32 may be located below the microfluidic detection chip 20. With this configuration, when the microfluidic detection chip 20 rotates to align a certain detection groove 21 with the corresponding light source 311, the light-emitting component 31 located on one side of the microfluidic detection chip 20 emits a light signal towards the detection groove 21, and the transparent microfluidic detection chip allows the light signal to pass through unobstructed, acting on the mixture within the detection groove 21 to excite the mixture to generate a feedback light signal. At this time, the receiving component 32, located on the other side of the chip and positioned opposite to the light-emitting component 31, can receive the feedback light signal after passing through the transparent microfluidic detection chip. There is no need to adjust the direction of light signal transmission, thus avoiding problems such as light signal loss and conduction obstruction caused by component position offset or the opacity of the microfluidic detection chip.

[0051] In other words, the relative arrangement of the light-emitting component 31 and the receiving component 32 in this embodiment, combined with the transparent microfluidic detection chip, allows the emission, penetration, excitation, and reception of light signals to form a continuous vertical transmission path, effectively improving the transmission efficiency and accuracy of light signals, while avoiding mutual interference between light signals of different detection items.

[0052] like Figure 7 As shown, in some embodiments, a drive motor 80 is provided on the body 10, and the drive motor 80 is driven to drive the microfluidic detection chip 20 to rotate.

[0053] As can be seen from the above description, the embodiments of this application achieve the following technical effects: (1) By setting up multiple light sources 311 and receiving components 32, and making each detection slot 21 pass through each light source 311 in sequence along the rotation direction of the microfluidic detection chip 20, multiple items can be detected at the same time, simplifying the operation process.

[0054] (2) This application sets up a first channel 313 and places the light source 311 in the first channel 313, which can separate each light source 311 and prevent the light signals of different light sources 311 from interfering with each other.

[0055] (3) In this application, a dustproof component 50 is provided between the first base 40 and the bottom of the microfluidic detection chip 20, and the dustproof component 50 covers the end of the second channel 41 away from the first channel 313, which can block external dust and other impurities from entering the interior of the second channel 41 and effectively prevent impurities from adhering to the inner wall of the second channel 41 and affecting the transmission of optical signals.

[0056] For ease of description, spatial relative terms such as "above," "on top of," "on the upper surface of," "above," etc., are used herein to describe the spatial positional relationship of a device or feature as shown in the figures to other devices or features. It should be understood that spatial relative terms are intended to encompass different orientations in use or operation beyond the orientation of the device as described in the figures. For example, if the device in the figures were inverted, a device described as "above" or "on top of" other devices or structures would subsequently be positioned as "below" or "under" other devices or structures. Thus, the exemplary term "above" can include both "above" and "below." The device may also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatial relative descriptions used herein will be interpreted accordingly.

[0057] Furthermore, it should be noted that the use of terms such as "first" and "second" to define components is merely for the purpose of distinguishing the corresponding components. Unless otherwise stated, the above terms have no special meaning and therefore cannot be construed as limiting the scope of protection of this application.

[0058] The above are merely preferred embodiments of this application and are not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. An analyzer for simultaneously detecting multiple items, characterized in that, include: Body (10); A microfluidic detection chip (20) is rotatably and replaceably disposed on the body (10). The microfluidic detection chip (20) has multiple detection slots (21), and each detection slot (21) contains detection reagents for different detection items. The detection component (30) is disposed on the body (10). The detection component (30) includes a light-emitting component (31) and a receiving component (32). The light-emitting component (31) includes multiple light sources (311), and each light source (311) emits a different wavelength. During the rotation of the microfluidic detection chip (20), each detection slot (21) passes through each light source (311) in sequence along the rotation direction of the microfluidic detection chip (20); when the detection slot (21) corresponds to the light source (311), the light source (311) emits a light signal to the detection slot (21), and the receiving component (32) is used to receive the light signal emitted from the detection slot (21).

2. The analyzer for simultaneously detecting multiple items according to claim 1, characterized in that, The light-emitting component (31) further includes a first support portion (312), and the light source (311) is disposed on the first support portion (312). The first support portion (312) has a plurality of first channels (313) extending along the height direction of the body (10). The light source (311) is disposed in the first channel (313) one by one. During the rotation of the microfluidic detection chip (20), each detection groove (21) passes through each first channel (313) in sequence along the rotation direction of the microfluidic detection chip (20). When the detection groove (21) corresponds to the first channel (313), the light source (311) emits a light signal to the detection groove (21) through the first channel (313).

3. The analyzer for simultaneously detecting multiple items according to claim 2, characterized in that, The first channel (313) includes a first branch channel (3131) and a second branch channel (3132) that are interconnected. The cross-section of the first branch channel (3131) is larger than the cross-section of the second branch channel (3132). The light source (311) is disposed in the first branch channel (3131).

4. The analyzer for simultaneously detecting multiple items according to claim 2, characterized in that, The body (10) is also provided with a first base (40), and the microfluidic detection chip (20) is disposed on the first base (40). The first base (40) has a plurality of second channels (41) extending along the height direction of the body (10). The second channels (41) are arranged one-to-one with the first channels (313). During the rotation of the microfluidic detection chip (20), each detection groove (21) passes through each second channel (41) in sequence along the rotation direction of the microfluidic detection chip (20). When the detection groove (21) corresponds to the second channel (41), the light source (311) emits a light signal to the detection groove (21) through the second channel (41).

5. The analyzer for simultaneously detecting multiple items according to claim 4, characterized in that, The body (10) is also provided with a dustproof component (50), which is located between the first base (40) and the bottom of the microfluidic detection chip (20), and the dustproof component (50) covers the end of the second channel (41) away from the first channel (313).

6. The analyzer for simultaneously detecting multiple items according to claim 5, characterized in that, The dustproof component (50) includes a light-transmitting element (51), and the light-transmitting element (51) includes a plurality of light-transmitting elements, and the light-transmitting elements (51) are respectively disposed at one end of the second channel (41) away from the first channel (313).

7. The analyzer for simultaneously detecting multiple items according to claim 6, characterized in that, The dustproof component (50) further includes a dustproof element (52), which is located on the side of the light-transmitting element (51) close to the microfluidic detection chip (20). The dustproof element (52) has multiple clearance holes (53), and the multiple clearance holes (53) are arranged one-to-one with the multiple light-transmitting elements (51).

8. The analyzer for simultaneously detecting multiple items according to claim 1, characterized in that, The receiving component (32) includes a second support (321) and a receiving plate (322). The second support (321) is disposed on the body (10) and has a plurality of third channels (323) extending along the height direction of the body (10). The third channels (323) are disposed one-to-one with the light source (311). The receiving plate (322) is disposed on the second support (321) and covers the third channels (323). When the detection slot (21) corresponds to the light source (311), the light source (311) emits a light signal to the detection slot (21), and the receiving plate (322) receives the light signal emitted from the detection slot (21) through the third channel (323).

9. The analyzer for simultaneously detecting multiple items according to claim 8, characterized in that, A second base (60) is provided on the body (10), and a second support (321) is provided on the second base (60). The second base (60) has an installation space (61) and a plurality of fourth channels (62) extending along the height direction of the body (10). The fourth channels (62) are provided in a one-to-one correspondence with the third channels (323). The microfluidic detection chip (20) is rotatably and detachably disposed in the installation space (61); and / or, A filter (70) is provided in the third channel (323) and / or the fourth channel (62).

10. The analyzer for simultaneously detecting multiple items according to any one of claims 1 to 9, characterized in that, The light-emitting component (31) and the receiving component (32) are located on opposite sides of the microfluidic detection chip (20) along the height direction of the body (10), and the microfluidic detection chip (20) includes a transparent microfluidic detection chip.

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