A cyclic peptide compound, and a preparation method and use thereof

By developing cyclic peptide compounds, the problem of insufficient selectivity of existing cyclin-CDK inhibitors has been solved, providing selective inhibitors of cyclin A and B for the treatment of various proliferative diseases, thus achieving more effective cancer treatment.

CN122255223APending Publication Date: 2026-06-23TUOJIE BIOTECH (SHANGHAI) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TUOJIE BIOTECH (SHANGHAI) CO LTD
Filing Date
2025-12-19
Publication Date
2026-06-23

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Abstract

The present disclosure relates to a cyclic peptide compound and its preparation method and use. Specifically, a compound represented by formula (I) is disclosed, a preparation method thereof, a pharmaceutical composition containing the same, and its use as a cyclin inhibitor for preventing and / or treating diseases, wherein each group in formula (I) is as defined in the specification.
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