A fluorescent photonic crystal enhanced PDMS / chitosan upconversion flexible biosensor and its application in rapid detection of food hazards
By utilizing a fluorescent photonic crystal-enhanced PDMS/chitosan upconversion flexible biosensor, and leveraging the fluorescence internal filtering effect of PMMA photonic crystals and nucleic acid aptamer-modified gold nanoparticles, the problems of weak fluorescence signal and background light interference in traditional detection methods are solved. This enables high-sensitivity and accurate detection of food hazards, making it suitable for rapid on-site detection.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- JIMEI UNIV
- Filing Date
- 2026-05-14
- Publication Date
- 2026-07-17
AI Technical Summary
In existing technologies, traditional detection methods lack accuracy and sensitivity in detecting food hazards, especially at low concentrations of target substances where the fluorescence signal is weak and background light interference is severe, making it difficult to achieve rapid on-site detection.
A flexible biosensor based on fluorescent photonic crystal-enhanced PDMS/chitosan upconversion was developed. The PMMA photonic crystal was used to modulate light, and a composite carrier was constructed by combining PDMS and chitosan. Nucleic acid aptamer-modified gold nanoparticles were used as probes. The fluorescence signal was significantly recovered through the fluorescence internal filtering effect, thus constructing a flexible sensing system.
It significantly improves the sensitivity and accuracy of food hazard detection, simplifies the pretreatment steps, is suitable for rapid on-site screening, has a good linear detection range and an extremely low detection limit, and can detect veterinary drug residues and antibiotic hazards in food.
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