A step-by-step synthetic reaction method of emamectin

Abstract

The present application relates to the technical field of step-by-step synthesis reaction, in particular to a step-by-step synthesis reaction method of emamectin benzoate, which extracts the heat trace path of raw materials in the preheating section and forms a propulsion trajectory line, selects a related heat band in the middle section to generate a conversion path diagram, positions each path and connects the conversion fluctuation section to form a rhythm structure, reflects the main and auxiliary material route adjustment entrance to realize collaborative propulsion, and connects the whole section to form a synthesis path paragraph set along the propulsion direction. The present application can form a comparable spatial clue by converting the heat diffusion change of the raw material after touching the wall into a path sequence, continuously track the reaction progress by observing the energy fluctuation and position change of the path in the middle section, present the stage connection rhythm by associating the start and end points of each path section, and facilitate the identification of the transition urgency. By comparing the main and auxiliary material paths, the approach area deviation can be captured to improve the consistency of the entry section. By integrating all path sections along the propulsion direction, the continuous coupling of multi-section reactions can be enhanced and the deviation can be reduced.

Description

Technical Field

[0001] This invention relates to the field of stepwise synthesis reaction technology, and more particularly to a stepwise synthesis reaction method for emamectin benzoate. Background Technology

[0002] The field of stepwise synthesis reaction technology includes the organization of the order of raw material addition, intermediate formation pathway, solvent usage, temperature range setting, stirring rate execution method, and separation and processing steps for multi-step chemical reactions. Specifically, it controls the composition of reactants, acid and base conditions, catalyst dosage, and by-product removal process through multiple sequential reaction steps, so that the target compound is gradually generated in continuous or batch operation. The core aspects of raw material pretreatment, single-step reaction execution, multi-step series reaction, solvent replacement, and solid-liquid separation process are the foundation of systematic chemical operation.

[0003] The traditional stepwise synthesis method of emamectin benzoate refers to setting multiple consecutive reaction steps to obtain emamectin benzoate through amination of the emamectin nucleus and salt formation reaction. Specifically, reactants containing methylamino functional groups are first added within a set temperature range and stirred to allow emamectin to undergo substitution or addition reactions. Then, benzoic acid or benzoate is added and the system is adjusted with a quantitative amount of acid or base to complete the salt formation step. Afterward, a solid product is obtained by solvent displacement and cooling crystallization, and the compound is obtained by solid-liquid separation. The traditional method usually completes the synthesis of emamectin benzoate by operating in the above sequence.

[0004] Existing technologies lack a spatial representation of the propagation state of raw materials within the cavity, making it difficult to capture differences in thermal diffusion and propagation deviations, and potentially leading to unidentified regional differences in the initial reaction stages. The lack of path correspondence in intermediate formation makes it difficult to observe the continuity of transformation, easily resulting in inaccurate judgments of reaction strength. The connection between reaction stages relies on experience, and the lack of continuous expression of the rhythmic changes in stage transitions may cause reaction fluctuations. The contact process between main and auxiliary materials in space cannot be identified by comparison, making it difficult to locate mixing deviation points. The overall reaction is organized only as a chain of steps, lacking a continuous structure along the propagation direction, resulting in insufficient correlation between multiple reaction stages and affecting the judgment and stability of the entire process. Summary of the Invention

[0005] To address the technical problems existing in the prior art, this invention provides a stepwise synthesis method for abamectin. The technical solution is as follows: A stepwise synthesis method for emamectin benzoate includes the following steps: S1: Observe the initial response of raw material touching the wall in the preheating start-up reaction section of abamectin, trace the path of raw material to the reaction chamber, extract the distribution band of thermal expansion traces and extend it to the inner wall propagation area, align the thermal trace extension interface at different times, separate the path band with the torsion point, and form the boundary trajectory line of raw material participation in the propagation. S2: Determine the regional boundary based on the trajectory line of the raw material participating in the advancement boundary, extend the heat trace path to the middle space, use the reaction phenomenon of the converted product in this space as a reference, select the continuous heat generation zone in the region, compare the reaction progress position and time, extract the path band related to the change of reactants, and form the intermediate conversion reaction distribution map line. S3: Call the intermediate conversion reaction distribution map line to mark the path zone, locate the reaction start point and end point of each path zone in sequence, compare the path changes and record the fluctuation segment, connect the path segments with frequent fluctuations in the degree of conversion, output the connecting zone continuously and unify it into a line to form a step-by-step reaction rhythm switching structure map line. S4: According to the step-by-step reaction rhythm, switch the path band in the structure diagram, map the main material and auxiliary material movement routes into the same space, observe the close section of the two routes, identify the offset segment in the close area, adjust the starting entrance of the auxiliary material route and correct the direction, so that it keeps the previous trajectory consistent with the main material route, and form a material collaborative propulsion trajectory structure. S5: Based on the path segments in the material collaborative propulsion trajectory structure, the main and auxiliary routes are simultaneously unfolded along the predetermined propulsion direction, and the reaction performance of each layer of material in the reaction section is laid out in sequence according to the propulsion direction. The path extension process connects all reaction sections, forming a set of stepwise synthesis reaction path segments of abamectin.

[0006] As a further embodiment of the present invention, the raw material participation in the advancement boundary trajectory line includes a heat distribution boundary layer, a boundary extension zone, and path segmentation nodes; the intermediate conversion reaction distribution path map includes a reaction evolution interval, a conversion characteristic zone, and an energy accumulation zone; the step-by-step reaction rhythm switching structure map specifically includes a rhythm partition sequence, a conversion connection point group, and a reaction step structure; the material collaborative advancement trajectory structure includes a route coupling transition zone, a collaborative matching section, and a synchronous advancement interface; and the emamectin benzoate step-by-step synthesis reaction path segment set specifically includes a segment sequence framework, a step-by-step partition system, and an advancement structure set.

[0007] As a further aspect of the present invention, the step of obtaining the boundary trajectory line of the raw material participation is as follows: S101: Observe the initial response of the raw material to the wall in the preheating start-up reaction section of abamectin. Record the contact path based on the outer edge contour of the raw material, the heating morphology of the wall surface and the position of the contact point at the moment of contact. Based on these records, determine the continuous change of the outer edge of the adhesion zone to form the initial propagation zone of the contact and generate the contact propagation morphology characteristics. S102: The contact wall propagation morphology features are called to track the transfer path of the raw material to the reaction chamber. The path extension direction is determined according to the contact wall propagation morphology features, the direction of the wall heating traces and the outer edge movement trajectory. The heat expansion trace distribution zone is extracted to form the path extension interval, and the path extension interval features are obtained. S103: The path extension interval features are called to align the thermal trace extension interfaces at different times. The interface correspondence is determined based on the path extension interval features, the outer edge position of the thermal expansion trace distribution zone and the interface sequence. The torsion point is determined accordingly to separate and connect the path zone to form an overall propulsion interface, and the raw material participation propulsion boundary trajectory line is obtained.

[0008] As a further aspect of the present invention, the step of obtaining the intermediate conversion reaction distribution curve is as follows: S201: Determine the region boundary based on the trajectory line of the raw material participating in the propulsion boundary, obtain the sequence of outer edge points of the trajectory line in space, determine the shape of the region boundary based on the positional relationship between the sequence of outer edge points and the wall of the reaction section, and establish the region boundary range accordingly. Extend the heat trace path to the middle section space within the range to generate the region boundary range interval. S202: Extend the heat trace path to the middle space by calling the area boundary range interval. Determine the continuous direction of the extended path in space according to the area boundary range interval, the arrangement relationship of the outer edge of the heat trace path and the arrangement order of the middle space position. Select the continuous heat generation zone according to the relationship between the extension direction and the position of the reaction phenomenon of the conversion product in the middle space to obtain the continuous heat generation zone sequence interval. S203: Call the continuous tropic zone sequence interval to compare the reaction progress position and time. Based on the continuous tropic zone sequence interval, the reaction progress time point, and the arrangement order of the tropic zones in the path, determine the correspondence between the path band and the reactant changes. Based on this, extract the corresponding path band from the sequence and connect them into a trajectory to obtain the intermediate conversion reaction distribution map.

[0009] As a further aspect of the present invention, the step of obtaining the step-by-step reaction rhythm switching structure graph is as follows: S301: Call the intermediate conversion reaction distribution map line to mark the path band, obtain the path band edge point sequence in the map line, determine the position of the reaction start point and end point based on the continuous change of the edge point sequence in the path band, and record the fluctuation segment based on the path change between the start point and end point to generate the path fluctuation segment segment. S302: The path fluctuation segment is called to determine the order relationship between the fluctuation segments based on the adjacency relationship between the path fluctuation segment and the path band in the sequence, and the path segments with frequent fluctuations in the degree of transformation are connected adjacently according to the order relationship to form a continuous output band, thus obtaining a continuous output band segment. S303: Call the continuous output strip segments to determine the connection relationship between segments according to the arrangement order of the continuous output strip segments in the path strip sequence, and uniformly organize the connecting strips according to the connection relationship and output the continuous trajectory line to obtain the step-by-step reaction rhythm switching structure diagram line.

[0010] As a further aspect of the present invention, the step of obtaining the material cooperative propulsion trajectory structure is as follows: S401: Based on the path band in the step-by-step reaction rhythm switching structure diagram, the main material and auxiliary material movement routes are mapped into the same space, the corresponding point sequence of the two routes in the space is obtained, the proximity relationship of the corresponding point sequence in the space is used to determine the position of the proximity segment, and the offset segment is identified based on the position change of the proximity segment to generate the offset segment interval. S402: Call the offset segment interval to determine the entrance correction direction based on the relative position of the offset segment interval and the starting entrance of the auxiliary material route in space, and adjust the starting entrance of the auxiliary material route according to the judgment result so that the correction direction is consistent with the trajectory of the front section of the main material route, and obtain the entrance correction segment. S403: Call the inlet correction segment to determine the connection order of the two routes based on the corresponding positional relationship between the inlet correction segment and the main material route front section trajectory, and then organize and output the auxiliary material route correction segment and the main material route front section in a unified manner according to the connection order to obtain the material collaborative propulsion trajectory structure.

[0011] As a further aspect of the present invention, the steps for obtaining the set of reaction pathway segments in the stepwise synthesis of abamectin are as follows: S501: Based on the path segments in the material collaborative propulsion trajectory structure, the main and auxiliary routes are simultaneously unfolded along the predetermined propulsion direction. The sequence of the main and auxiliary routes in the propulsion direction is obtained. The unfolding correspondence of the two routes is determined according to the front-to-back position relationship of the sequence of the points in the propulsion direction. Based on the correspondence, the reaction performance of each layer of material in the reaction section is unfolded in the propulsion direction in sequence to generate the propulsion unfolding segment. S502: The propulsion and spreading segment is invoked to determine the connection sequence of the path extension process based on the positional relationship between the propulsion and spreading segment and the path segment within the reaction segment, and the path segments are connected one by one according to the connection sequence so that they form a continuous extension flow between the reaction segments, thus obtaining a connected segment. S503: Call the connecting segment to determine the serialization logic between segments based on the overall arrangement relationship between the connecting segment and the reaction segment, and sort each advancement segment in a unified order according to the serialization logic and output the path segment set to obtain the stepwise synthesis reaction path segment set of emamectin benzoate.

[0012] The beneficial effects of the technical solutions provided in the embodiments of the present invention include at least the following: In this invention, by converting the thermal diffusion changes of raw materials upon contact with the wall into a path sequence, the differences in the material's propulsion within the cavity can be made into comparable spatial clues. Through the extension of these paths in the mid-section space, energy fluctuations and positional changes in the reaction zone can be observed, allowing the reaction progress to exhibit a continuously traceable pattern. By associating the start and end positions of each path segment, the transition rhythm of reaction stages can be presented, making the rapid and slow states during stage transitions easily identifiable. By comparing the main and auxiliary material routes in a common space, offsets in the proximity zone can be captured, maintaining higher consistency in the material entry section. By integrating all path segments along the propulsion direction, multiple reaction segments can form a continuous relationship, increasing the coupling between reaction stages and reducing process deviations. Attached Figure Description

[0013] Figure 1 This is a flowchart of the method of the present invention; Figure 2 This is a flowchart illustrating the process of obtaining the boundary trajectory line of the raw materials involved in the propulsion of this invention. Figure 3 This is a flowchart illustrating the process of obtaining the distribution path of the intermediate conversion reaction in this invention. Figure 4 This is a flowchart illustrating the process of obtaining the step-by-step reaction rhythm switching structure diagram of the present invention. Figure 5 This is a flowchart illustrating the process of obtaining the material collaborative propulsion trajectory structure according to the present invention. Figure 6 This is a flowchart illustrating the process of obtaining the reaction pathway segments for the stepwise synthesis of abamectin in this invention. Detailed Implementation

[0014] The present invention will now be described in further detail with reference to the accompanying drawings. These drawings are simplified schematic diagrams, illustrating only the basic structure of the invention, and therefore only show the components relevant to the invention.

[0015] refer to Figures 1 to 6 A stepwise synthesis method for emamectin benzoate includes the following steps: S1: In the preheating start-up reaction section of abamectin, observe the initial response after the raw material touches the wall, trace the path of the raw material into the reaction chamber, extract the distribution band of thermal expansion traces, extend it to the propagation area on the inner wall of the chamber, align the thermal trace extension interfaces at different times in the path, separate the path torsion points into multiple continuous path bands, and form the boundary trajectory line of the raw material participating in the propulsion. S2: Based on the regional boundaries shown by the trajectory lines of the raw materials participating in the advancement, each heat trace path is extended to the middle space. The reaction phenomena of the conversion products generated in this space are used as a reference. The continuous heat generation areas in each region are selected one by one, and their reaction progress positions and times are compared. The path bands that are significantly related to the changes of reactants are extracted to form the distribution path map of the intermediate conversion reaction. S3: Call the various path bands displayed in the intermediate transformation reaction distribution path diagram, locate the reaction start and end points of each path band, complete the location at the path level according to the order of appearance, pay attention to the changes between paths, connect the path segments with frequent fluctuations in the degree of transformation, and output these connecting bands in a continuous manner to form a step-by-step reaction rhythm switching structure diagram. S4: According to the step-by-step reaction rhythm, switch the path band in the structure diagram, map the movement routes of the main material and the auxiliary material into the same space, observe the close section of the two routes, identify the offset segment in the close area of ​​the two path trajectories, adjust the starting entrance of the auxiliary material route to keep it consistent with the previous trajectory of the main material route, and form a material collaborative propulsion trajectory structure. S5: Based on the path segments in the material collaborative propulsion trajectory structure, the main and auxiliary routes are simultaneously unfolded along the predetermined propulsion direction, and the reaction performance of each layer of materials in the reaction section is unfolded sequentially along the propulsion direction. The entire reaction section is connected through the path extension and propulsion process to form a set of reaction path segments for the stepwise synthesis of abamectin.

[0016] The raw material participation boundary trajectory line includes the heat distribution layer, boundary extension zone, and path segmentation nodes; the intermediate conversion reaction distribution path line includes the reaction evolution interval, conversion characteristic zone, and energy accumulation zone; the step-by-step reaction rhythm switching structure line specifically includes the rhythm partition sequence, conversion connection point group, and reaction step structure; the material collaborative advancement trajectory structure includes the route coupling transition zone, collaborative matching section, and synchronous advancement interface; the step-by-step synthesis reaction path segment set of emamectin benzoate specifically includes the segment sequence framework, step-by-step partition system, and advancement structure set.

[0017] Please see Figure 2 The steps for obtaining the boundary trajectory line of the raw materials involved in propulsion are as follows: S101: Observe the initial response of the raw material to the wall in the preheating start-up reaction section of abamectin. Record the contact path based on the outer edge contour of the raw material, the heating morphology of the wall surface and the position of the contact point at the moment of contact. Based on these records, determine the continuous change of the outer edge of the adhesion zone to form the initial propagation zone of the contact and generate the contact propagation morphology characteristics. During the preheating stage, the movement of the abamectin raw material after entering the reaction chamber is continuously acquired. The imaging device records the contour of the outer edge before it approaches the inner wall at 120fps. The temperature matrix is ​​updated every 0.05s. The shortest distance from the outer edge to the wall is read frame by frame and listed as a distance sequence. By comparing the distance difference between two frames, when the distance in a certain frame shrinks by more than 0.15mm relative to the previous frame, the shortest distance point of the outer edge in that frame is taken as the wall contact point. At the same time, the difference between the corresponding wall temperature and the preheating reference temperature is recorded as the temperature rise value at that point. For example, if the preheating reference temperature is 182℃ and the temperature displayed at the moment of wall contact is 187℃, then the temperature rise is 5℃. The spatial position of the wall contact point is expressed by the circumferential angle θ and the axial height z. For example, the position is θ=32°, z=14. By recording multiple contact points sequentially and arranging them chronologically in a data table, a contact sequence can be formed. For adjacent points in the sequence, the angle and height increments are checked. When the angle increment is between 1° and 10° and the height increment is between 0.5 mm and 4 mm, these points are considered to belong to the same propagation direction segment. For example, if three consecutive points are (32°, 14mm), (36°, 16mm), and (41°, 17mm), the angle changes are 4° and 5° respectively, and the height changes are 2mm and 1mm respectively, all falling within the range. Therefore, these three points can be considered to reflect the same propagation trend. These trends are then concatenated chronologically. If the angle difference between two trends does not exceed 12° and the height difference does not exceed 6mm, then continuity is established. The propagation segment forms a complete propagation band according to this logic. The outer edge sequence is listed based on the outermost coordinates of the contact point at each moment, and the displacement of the outer edge in the angle and height directions is compared chronologically. For example, at a certain moment, the outer edge point is located at θ=45°, z=18°. mm, at the next moment the outer edge point is located at θ=50°, z=19mm, then the angle direction shifts to the right by 5° and the height direction rises by 1mm. After this trend of change is continuously recorded, the outer edge trajectory of the contact wall morphology can be presented as time progresses, and the contact wall propagation morphology characteristics can be obtained.

[0018] S102: The path of raw material transfer to the reaction chamber is traced by calling the wall-contact propagation morphology characteristics. The path extension direction is determined based on the wall-contact propagation morphology characteristics, the direction of wall heating marks, and the outer edge movement trajectory. The path extension interval is then extracted by extracting the thermal expansion mark distribution zone. The path extension interval characteristics are obtained. After organizing the wall-contact propagation morphology features in chronological order, the outer edge point and surrounding wall temperature points at each moment are compared. By comparing the temperature differences between the four surrounding points, the direction of more significant temperature increase is identified. For example, near the outer edge point, the upper side temperature is 191℃, the lower side temperature is 187℃, the right side temperature is close to 190℃, and the left side temperature is 185℃. The upper side is 4℃ higher than the lower side, and the right side is 5℃ higher than the left side. Therefore, the temperature extension direction is slightly upward and to the right. Then, the angle between the temperature extension direction and the actual displacement direction of the outer edge point is determined. By observing the offset relationship between the two directions on the angle scale, when the offset is in a small angle range, such as less than 30°, it can be classified as a consistent direction, thus forming an extension band at each moment. The lateral and longitudinal positions of the outer edge point of the extension band are scanned and compared point by point. The difference between adjacent points, for example, if the horizontal span of adjacent points falls within the range of 1mm to 8mm and the vertical span falls within the range of 10mm to 60mm, they belong to the same card area. All card areas are arranged into multiple extension intervals in chronological order. Then, each interface is processed according to the sorting method of the outer edge points at each moment. The sorting results of interfaces at different times are compared by sorting them at the same angle. For example, if the distance between points with the same serial number in two interfaces falls within the range of 0.5mm to 5mm, they can be regarded as having a corresponding relationship. These corresponding relationships are used to maintain the overall consistency of the arrangement between interfaces and to align the thermal trace interfaces at multiple moments in a unified coordinate system. Through such a correction sequence and card area division logic, the directional change and positional segment change of thermal trace extension over time can be clearly identified, and the path extension interval characteristics can be obtained.

[0019] S103: Call the path extension interval features to align the thermal trace extension interfaces at different times. Based on the path extension interval features, the outer edge position of the thermal expansion trace distribution zone and the interface sequence, determine the interface correspondence and determine the torsion point to separate and connect the path zone to form an overall propulsion interface, and obtain the raw material participation propulsion boundary trajectory line.

[0020] The path extension interval feature is used to provide a sequence of outer edge points for each time interface. These outer edge points are rearranged in ascending order of angle. The spacing between corresponding points on two adjacent time interfaces is compared. When the angle difference falls within the range of 0.5° to 6° and the height difference falls within the range of 0.3mm to 5mm, continuity is maintained, thus forming a correspondence. The direction of height change of continuous correspondences is compared. When two consecutive height changes have the same sign and the next change in sign (e.g., the first two height increments are positive and the next height increment becomes negative), then this position reflects a path direction twist and can be identified as a twist point. After all the torsion points are sorted by time, the advancement segments between different torsion positions of each interface can be divided. The outer edge points between each advancement segment are connected in time sequence to form the advancement interface. The outermost position of the advancement interface is connected point by point to present the outer edge of the overall path. For example, the outermost point of a certain segment is located at (θ=38°, z=20mm), (θ=44°, z=22mm), and (θ=49°, z=23mm) in sequence. After being connected, an advancement line that gradually deviates to the upper right over time can be obtained. The advancement trajectory formed by the sequence of all advancement lines in time is the leading edge advancement trajectory line, and the boundary trajectory line of the material participation advancement is obtained.

[0021] Please see Figure 3 The steps for obtaining the distribution curve of intermediate conversion reaction are as follows: S201: Determine the regional boundary based on the trajectory line of the raw material participating in the propulsion boundary, obtain the sequence of outer edge points of the trajectory line in space, determine the shape of the regional boundary based on the positional relationship between the sequence of outer edge points and the wall of the reaction section, and establish the range of the regional boundary accordingly. Extend the heat trace path to the middle section space within the range to generate the range of the regional boundary. The spatial positions of the outer edge points are read based on the trajectory line of the raw material propulsion boundary. These outer edge points are arranged in chronological order to form a coordinate sequence. For example, the outer edge points of a certain segment of the trajectory line are (θ=33°, z=21mm), (θ=39°, z=24mm), and (θ=46°, z=27mm). A point-by-point comparison is performed between the outer edge points and the reaction section wall. The spatial interval value is obtained by subtracting the height difference between the wall and the corresponding angular direction from the height difference of the outer edge point. All interval values ​​are then arranged into a distance sequence and classified according to intervals. When the interval value is between 2mm and 6mm, the point is determined to be in the section close to the wall; when the interval value is between 6mm and 14mm, it is determined to be in the middle section; when the interval value exceeds 14mm... When the value is mm, it is determined to be in a region far from the wall. The continuity of the trend of change along the angular direction of the outer edge points is judged. By comparing the angle increment and height increment of adjacent outer edge points, when the angle increment falls within the range of 3° to 10° and the height increment falls within the range of 1mm to 5mm, it indicates that the trajectory segment exhibits a stable outward trend. For example, the angle increments of the aforementioned three points are 6° and 7°, and the height increments are 3mm and 3mm, both within the range. Therefore, this trajectory segment has the characteristic of continuous outward advancement. The spatial arrangement of each point is determined according to the direction of outward advancement. The boundary shape of the region is constructed by extracting four parameters—minimum angle, maximum angle, minimum height, and maximum height—that appear in a certain segment of the trajectory line. For example, the minimum angle is 33°, the maximum... Angle 46°, minimum height 21mm, and maximum height 27mm form a set of area boundary coordinate ranges. Then, the thermal trace path is extended to the middle section space according to this range. The extension action is performed by offsetting each outer edge point into the space at a fixed distance increment, for example, the offset increases from 2mm to 12mm. After each offset, the position of the offset point is judged to confirm whether it is still within the area boundary range. When the angle coordinate of the offset point is between 33° and 46° and the height is between 21mm and 27mm, the point is recorded as a valid extension point. Through continuous offset and judgment actions, an extension point sequence is formed. The extension point sequence gradually expands and covers the middle section area under the condition of the area boundary space range, generating the area boundary range interval.

[0022] S202: Extend the heat trace path to the middle space by calling the regional boundary range interval. Determine the continuous direction of the extended path in space based on the regional boundary range interval, the arrangement relationship of the outer edge of the heat trace path, and the arrangement order of the middle space position. Select the continuous heat generation zone based on the relationship between the extension direction and the position of the reaction phenomenon of the conversion product in the middle space to obtain the continuous heat generation zone sequence interval. After determining the range of the calling region boundary, the outer edge points of the heat trace path are reordered. The sorting is based on the angular coordinates from smallest to largest, for example, the outer edge points are arranged in order of θ=34°, 41°, and 47°. The corresponding height coordinates are read to form a point sequence. At the same time, according to the division method of the middle section space, the height direction is assigned a number at fixed intervals. For example, the 20mm to 40mm interval is divided into height segments of 2mm. For the outer edge points, a comparison is performed item by item with the height segments. For example, the outer edge point with a height of 26mm corresponds to the height segment 24–26mm. This comparison process, using mm, completes the index matching between the outer edge point and the mid-section spatial position. Based on the region boundary range, spatial constraints are applied to the outer edge point. When the outer edge point's angle and height coordinates are within the region boundary angle range, it is determined that the point has the potential for extension. Then, continuous direction judgment is performed on the angle and height changes between adjacent outer edge points. When the angle change is between 2° and 9° and the height change is between 1mm and 4mm, it indicates that the path segment has a continuous propagation tendency. For example, at the first moment, the outer edge point's angle is 34° and its height is 24mm; at the next moment, the outer edge point's angle is 39° and its height is 27mm. mm, both increments are within the interval, therefore directional continuity is established. Matching is performed on the continuous directional path points and the locations of the conversion reaction phenomena in the middle space. By reading the points with significant temperature increases in the reaction phenomenon monitoring data, for example, at a certain moment θ=38°, z=28mm, the temperature is 3°C higher than the surrounding area. The interval judgment shows that the temperature rise at this point is within the reaction phenomenon identification threshold range. Then, the angle difference and height difference between the continuous path points and the heating points are numerically compared. When the angle difference is less than 7° and the height difference is less than 5mm, the continuous path points are classified into continuous heating zones. By continuously comparing adjacent path points with heating points at multiple moments, multiple continuous heating zones can be formed. Then, these heating zone positions are rearranged in chronological order, thus obtaining the continuous heating zone sequence interval.

[0023] S203: Call the continuous tropic zone sequence interval to compare the reaction progress position and time. Based on the continuous tropic zone sequence interval, the reaction progress time point, and the arrangement order of the tropic zones in the path, determine the correspondence between the path band and the reactant changes. Based on this, extract the corresponding path band from the sequence and connect them into a trajectory to obtain the intermediate conversion reaction distribution map.

[0024] After establishing the continuous heat generation sequence intervals, the points in each sequence interval are read in chronological order. For example, time t1 is (θ=36°, z=25mm), time t2 is (θ=42°, z=28mm), and time t3 is (θ=47°, z=32mm). The reaction progress time points are read from data recorded every 10 seconds during the conversion rate monitoring process. For instance, the conversion rate reaches 15%, 27%, and 41% at 30s, 60s, and 90s of reaction, respectively. These time points form a reaction progress time point sequence. By comparing the time labels of the sequence intervals with the time points item by item, a correspondence is considered valid when the time difference is within 5 seconds. The spatial arrangement order of the continuous heat generation points is then determined by analyzing the heat generation points from the smallest to the largest angle. The angles are arranged sequentially from largest to smallest, and the arrangement order is compared with the reaction progress time order. When the order of the two is consistent, it indicates that the correspondence is stable. For example, the continuous tropics angles are arranged as 36°, 42°, and 47°, while the corresponding reaction progress time order is 30s, 60s, and 90s. The consistency of the two sequences indicates that the match is established. The path band is extracted from the continuous tropics sequence according to this correspondence. By connecting the points of the path band in space in ascending order of time, a continuous trajectory can be formed. For example, connecting the points at three time points in sequence can form a spatial path line that gradually advances from θ=36° to θ=47°. The changes of this path line at different times can be extended and connected to form the reaction distribution trend line in the middle space, and the intermediate transformation reaction distribution line can be obtained.

[0025] Please see Figure 4 The steps for obtaining the step-by-step reaction rhythm switching structure graph are as follows: S301: Call the intermediate conversion reaction distribution map line to mark the path zone, obtain the path zone edge point sequence in the map line, determine the reaction start point and end point position based on the continuous change of the edge point sequence in the path zone, and record the fluctuation segment based on the path change between the start point and end point to generate the path fluctuation segment segment. After calling the intermediate transformation reaction distribution map, edge points on the path band are extracted sequentially over time. This extraction is accomplished by reading the outermost coordinate point at each moment in the map. For example, the edge points at times t1, t2, and t3 are (θ=36°, z=24mm), (θ=41°, z=28mm), and (θ=47°, z=31mm), respectively. The continuous changes of these edge points within the path band are then evaluated. This evaluation is performed by comparing the angle difference and height difference between adjacent points one by one. When the angle difference is between 3° and 1°... A continuous change is considered to occur when the angle difference is between 0° and the height difference is between 2mm and 6mm. For example, if the angle difference between t1 and t2 is 5° and the height difference is 4mm, and the angle difference between t2 and t3 is 6° and the height difference is 3mm, both meet the conditions for continuous change, thus confirming that these three points are in a continuous segment. Then, the start and end point identification actions are performed on the endpoints of the continuous segment. This identification action is implemented by checking whether there are points that meet the continuity conditions at the two ends of the continuous segment before and after the specified time. For example, before t1, there are no points where the angle difference falls between 3° and 10° and the height difference falls between 2mm and 6mm. Points ranging from mm to 6mm are considered as starting points, with the edge point of t1 being the starting point. Similarly, since there are no subsequent points satisfying the conditions after t3, the edge point of t3 is considered the ending point. The fluctuation segment recording action is performed based on the path changes between the starting and ending points. The fluctuation segment recording is performed by calibrating points where the direction of angle change and the direction of height change within the path band are reversed. For example, if the angle value rises from 41° to 45° and then falls to 43° in a certain segment, this position is considered a fluctuation node. At least two points are taken before and after the fluctuation node to compare the change trends. When the comparison finds that the change directions of the two segments are inconsistent, a fluctuation segment is formed. Then, all fluctuation nodes are sorted by number to form a fluctuation segment fragment sequence composed of multiple small segments. This process is repeated continuously in the path band to form a complete path fluctuation segment fragment, thus generating a path fluctuation segment fragment.

[0026] S302: Call the path fluctuation segment fragment. Determine the order relationship between fluctuation segments based on the adjacency relationship between the path fluctuation segment fragment and the path band in the sequence. Connect the path segments with frequent changes in the degree of transformation according to the order relationship to form a continuous output band and obtain a continuous output band fragment. After the path fluctuation segment is formed, the relative position of the segment within the overall path sequence is adjusted. This adjustment is performed by reading the starting node number of each segment. For example, if the starting numbers of three segments are 6, 13, and 18, the adjacency relationship is determined by comparing the differences between these numbers. If the difference between the starting number of the next segment and the ending number of the previous segment is between 1 and 3, the segment is considered adjacent. When determining the interval, it is determined that the two segments are in a sequentially adjacent state. For example, if the end number of segment 1 is 9 and the start number of segment 2 is 13, the difference of 4 exceeds the interval, so segment 1 and segment 2 are not adjacent. However, if the end number of segment 2 is 15 and the start number of segment 3 is 18, the difference of 3 falls within the interval, so segment 2 and segment 3 are adjacent. Then, a path segment connection action is performed based on the adjacent relationship. The connection action is implemented by performing a dual judgment on the angle increment and height increment of the end point of the adjacent segment and the start point of the other segment. When the angle increment is in the range of 2° to 8° and the height increment is in the range of 1mm to 5mm, the trends between the segments are consistent. For example, the end point of segment 2 is θ=44°, z=29. For segment 3, the starting point is θ=48° and z=32mm. The angle increment of 4° and the height increment of 3mm both fall within the interval, indicating that the connection condition is met. Based on this condition, several points with increasing angle and height are inserted between the two segments, such as θ=46°, z=30mm and θ=47°, z=31mm, to make the connection more continuous. Then, multiple rounds of connection actions are performed on all segments that meet the connection condition to gradually form a structurally continuous output sequence. After the output sequence is constructed, all segments that constitute the output sequence are uniformly classified as continuous output strip segments to obtain continuous output strip segments.

[0027] S303: Call the continuous output strip segments to determine the connection relationship between segments based on the arrangement order of the continuous output strip segments in the path strip sequence, and uniformly organize the connecting strips according to the connection relationship and output the continuous trajectory line to obtain the step-by-step reaction rhythm switching structure diagram line.

[0028] After generating continuous output segments, the sorting process establishes an order by ranking the angle coordinates of the first point of each segment. For example, if the first point angles of three segments are 38°, 44°, and 53°, they are sorted as 38°, 44°, and 53°. Then, a connection check is performed on the first and last points of adjacent segments in the sorted result. This check is done by comparing the angle offset and height offset within a range. If the angle offset is less than 9° and the height offset is less than 6°, the connection is established. When the distance is mm, the connection condition is considered met. For example, at the end of segment 1, θ=43° and z=27mm, and at the beginning of segment 2, θ=44° and z=28mm. The offsets of 1° and 1mm are both within the range, so the connection relationship is established. The points of the two segments are then connected. The connection action is to ensure structural uniformity by arranging all points of the two segments in chronological order and performing a continuity check on their angle change trends. When the angle value shows a continuous increasing trend and the height change does not show a reverse fluctuation, it indicates that the path after connection is stable. Then, a sorting action is performed on any redundant points that may appear after connection. This action is completed by deleting points whose angle increment and height increment are both lower than the set lower limit. For example, when the angle increment is lower than 0.5° and the height increment is lower than 0.4mm, it is considered redundant. Deleting redundant points enhances the path coordination. All segments that have been connected are sorted in overall chronological order, and the sorting results are checked again according to the path continuity to ensure that there are no breaks in the segments in the spatial and temporal directions. This forms a complete and continuous trajectory line, which is presented as a step-by-step reaction rhythm switching structure line.

[0029] Please see Figure 5 The steps for obtaining the material collaborative propulsion trajectory structure are as follows: S401: According to the step-by-step reaction rhythm, switch the path band in the structure diagram to map the main material and auxiliary material movement routes into the same space, obtain the corresponding point sequence of the two routes in space, determine the position of the close segment according to the proximity relationship of the corresponding point sequence in space, and identify the offset segment based on the position change of the close segment to generate the offset segment interval. According to the step-by-step reaction rhythm, the path bands in the structure diagram are switched to map the main material route and the auxiliary material route into the same space. This action is accomplished by reading the angle and height coordinates of the two routes in a unified coordinate system. For example, the positions of the main material at t1, t2, and t3 are (θ=30°, z=20 mm), (θ=36°, z=24 mm), and (θ=42°, z=27 mm), respectively, and the positions of the auxiliary material route at the corresponding times are (θ=34°, z=19 mm), (θ=39°, z=23 mm), and (θ=45°, z=26 mm). A step-by-step comparison is performed between the two point sequences. A corresponding point sequence is formed by calculating the angle difference and height difference between the two points. When the angle difference is between 2° and 9° and the height difference is between 1 mm and 7 mm, it is recorded as a close point pair. For example, at t1, the angle difference is 4° and the height difference is 1 mm, and at t2, the angle difference is 3° and the height difference is 1 mm. These points all fall within the proximity interval. After recording, these proximity point pairs are arranged in chronological order to form proximity segments. The spatial positional changes of the proximity segments are identified by performing trend judgment on the angle and height changes of each point within the proximity segment. This trend judgment is implemented by comparing the increments of angle and height differences between adjacent proximity points point by point. When the increment of angle difference increases from less than 3° to more than 7°, or when the increment of height difference increases from less than 2mm to more than 5mm, it is considered that an offset behavior has occurred. For example, in the comparison of t2→t3, the auxiliary material route point θ=45°, z=26 The angle difference between mm and the main material route (θ=42°, z=27mm) increases from 3° to 3°, but the height difference increases from 1 mm to 1 mm without creating an offset. However, in another segment, at the auxiliary material point (θ=50°, z=30mm), the angle difference immediately jumps to over 8° and the height difference to over 3mm. This identifies the offset start point. Continuous scanning is then performed on points after the offset start point. When the angle difference of three consecutive points remains above 7° and the height difference remains above 3mm, these points are marked as offset segments. The start and end numbers of the offset segments are recorded in a sequence. Multiple offset segments are then sequentially arranged according to their original spatial order to form a complete offset segment interval. S402: Call the offset segment interval to determine the entrance correction direction based on the relative position of the offset segment interval and the starting entrance of the auxiliary material route in space, and adjust the starting entrance of the auxiliary material route according to the judgment result so that the correction direction is consistent with the trajectory of the front section of the main material route, and obtain the entrance correction segment. After calling the offset segment interval, a comparison is performed between the center position of the offset segment in space and the spatial position of the starting entrance of the auxiliary material route. This action is carried out by reading the angle and height values ​​of the initial point of the auxiliary material entrance and subtracting them from the angle and height values ​​of the center point of the offset segment. For example, if the auxiliary material entrance is located at θ=28°, z=18mm, and the center point of the offset segment is at θ=37°, z=24mm, the angle difference is 9° and the height difference is 6mm. An interval judgment is performed on these two differences. When the angle difference falls into the range of 6° to 12° and the height difference falls into the range of 4mm to 10mm, the entrance direction is considered to deviate significantly from the main material route, and correction is required in the direction of increasing angle and increasing height. Then, based on this judgment result, the coordinates of the auxiliary material entrance are adjusted. This action is performed by gradually correcting the entrance by increasing the angle by 1° each time and the height by 1mm each time. The position is compared with the previous point of the main material route immediately after each correction to ensure that the correction direction tends to the movement trend of the previous section of the main material. For example, the position of the previous section of the main material at t1 and t2 is (θ=30°, z=20mm) and (θ=35°, z=23mm). After two correction steps, the auxiliary material inlet may reach (θ=30°, z=20mm). At this time, the angle difference is 0° and the height difference is 0mm, which meets the trend characteristics of the previous section. When more correction steps are performed, if the angle difference and height difference are found to exceed the range of 3° and 3mm respectively, the correction is reversed and readjusted to ensure that the inlet position is always in the interval corresponding to the movement direction of the previous section of the main material. The inlet correction segment is formed by sequentially recording the coordinates of all correction steps. When the correction segment can show an increasing trend in angle and increasing trend in height at each time, it is considered to meet the requirements, thus forming a complete inlet correction segment.

[0030] S403: Call the entry correction segment. Based on the corresponding positional relationship between the entry correction segment and the main material route front section trajectory, determine the connection order of the two routes. According to the connection order, organize the auxiliary material route correction segment and the main material route front section in a unified manner and output them in series to obtain the material collaborative propulsion trajectory structure.

[0031] After invoking the entry correction segment, a correspondence determination is performed between the correction segment and the points in the preceding section of the main material route. This determination is implemented by comparing the angle and height coordinates of the two sequences item by item. For example, the positions of the correction segment at t1 and t2 are (θ=31°, z=19mm) and (θ=33°, z=22mm), respectively, while the corresponding points in the preceding section of the main material route are (θ=30°, z=20mm) and (θ=35°, z=23mm). When the angle difference between the two is in the range of 1° to 4° and the height difference is in the range of 1mm to 4mm, they can be identified as corresponding points. All corresponding points are arranged in chronological order, and a judgment action is performed on their changing trends. This is done by comparing the angle increment and height increment of adjacent corresponding points item by item. When the direction increments of the two routes are of the same sign and the angle increment falls within the range of 2° to 8° and the height increment falls within the range of 1mm, a corresponding point is identified. When the connection trend is consistent within the range of mm to 5mm, the connection trend can be confirmed. Then, the connection trend of the points with consistent connection trends is connected in series. This action is carried out by merging two sequences and sorting them by angle coordinates from smallest to largest. During the merging process, if the angle increment of some points is less than 0.5° and the height increment is less than 0.4mm, they are considered redundant points and deleted to make the route more coherent. Then, the connected route is uniformly sorted. The final continuity check of the overall route is performed to avoid the occurrence of angle reversal or height reversal. When all checks pass, the route connection is completed and the connected route is output as a structure, thus forming a collaborative propulsion trajectory structure between materials.

[0032] Please see Figure 6 The steps for obtaining the set of reaction pathway segments in the stepwise synthesis of abamectin are as follows: S501: Based on the path segments in the material collaborative propulsion trajectory structure, the main and auxiliary routes are simultaneously unfolded along the predetermined propulsion direction. The sequence of points of the main and auxiliary routes in the propulsion direction is obtained. The unfolding correspondence of the two routes is determined according to the front-to-back position relationship of the sequence of points in the propulsion direction. Based on the correspondence, the reaction performance of each layer of material in the reaction section is unfolded in the propulsion direction in sequence to generate the propulsion unfolding segment. Based on the path segments in the material collaborative propulsion trajectory structure, the main material route and the auxiliary material route are synchronously deployed along a predetermined propulsion direction. This action is completed by reading the sequential points of the two routes along the same propulsion axis and arranging them according to time sequence. For example, the points of the main material route in the propulsion direction are (θ=31°, z=21mm), (θ=37°, z=25mm), and (θ=42°, z=28mm), while the points of the auxiliary material route in the propulsion direction are (θ=33°, z=20mm). For the two routes (θ=38°, z=24mm) and (θ=46°, z=29mm), a corresponding point relationship determination is performed on the sequential point sequences. This determination is achieved by comparing the angle difference and height difference of each pair of points item by item. When the angle difference is between 2° and 8° and the height difference is between 1mm and 6mm, they are recorded as corresponding point pairs. For example, the first pair of points has an angle difference of 2° and a height difference of 1mm, and the second pair of points has an angle difference of 1° and a height difference of 1mm, both of which meet the corresponding conditions. Then, the corresponding point sequences are determined based on their position relative to each other in the direction of advancement. The relationship between the two routes is determined by checking whether the angle changes of the two routes are synchronous and whether the height changes are within similar increment ranges. When the angle increment between adjacent points of the main and auxiliary routes is between 4° and 9° and the height increment is between 2mm and 5mm, it is considered to have synchronous development characteristics. For example, if the main material's angle increases from 31° to 37° and the auxiliary material's angle increases from 33° to 38°, both increasing by 5°, and the height increases by 4mm and 4mm respectively, it can be confirmed that the two routes are synchronous in the direction of advancement. This relationship is then mapped to the material layers in the reaction section. The reaction position recorded in each material layer is read and arranged according to the direction of advancement. When the reaction position of a certain layer falls between the corresponding points of the main and auxiliary routes and the difference between its angle and height coordinates and the two points is within 3° and 3mm, it is included in the spreading layer position. The same sequential arrangement is performed on the multi-layer data, and all layers are integrated into a continuous sequence according to the direction of advancement. This continuous sequence is then recorded as the advancing spreading segment.

[0033] S502: Call the propulsion and spreading segment. Based on the positional relationship between the propulsion and spreading segment and the path segment within the reaction segment, determine the connection sequence of the path extension process, and connect the path segments one by one according to the connection sequence, so that it forms a continuous extension flow between the reaction segments, and obtain the connected segment. After the propulsion and spreading segment is invoked, its position within the reaction segment is compared with its position within the path segment. This comparison is performed segment by segment. This is done by reading the sequence number of each depth layer in the spreading segment and comparing it with the corresponding depth layer sequence number in the path segment. For example, if the depth layer sequence numbers of the spreading segment are 3, 4, and 6, and the depth layer sequence numbers of the path segment are 2, 3, and 4, then the difference between the spreading depth layer and the path segment depth layer is between 1 and 2. When the layers are intersecting, it is considered that the two have the conditions for connection. Then, the angle coordinates are compared and judged again. When the angle difference is between 3° and 10°, it means that the path extension direction is consistent with the paving direction. For example, if the paving point θ=40° and the path segment θ=37°, the difference of 3° meets this range, thus determining that the two segments have the possibility of extension and connection. Then, according to the connection relationship, the connection sequence is arranged. The points in each segment that meet the connection conditions are arranged in ascending order according to the advancement direction. When the depth layer number of adjacent points always increases in the direction of advancement and the increment does not exceed 2 layers, it is recorded as a continuous connection segment. For example, the numbering from 3→4→6 is relatively large across layers, but each segment... If the internal direction of change remains the same, it can be considered as an extended structure. Then, a connection action is performed on multiple continuous segments. This action is based on the angle difference and height difference between the interface points of two segments. When the angle difference is between 4° and 9° and the height difference is between 2mm and 6mm, they can be connected. For example, the end of path segment A is (θ=39°, z=26mm) and the beginning of path segment B is (θ=44°, z=29mm). The difference of 5° and 3mm both fall within the allowable connection range. Then, these segments are arranged into a continuous flow direction according to the connection order. By accumulating and sorting all the segments that meet the conditions, the connected segments can be obtained.

[0034] S503: Call the connecting segment to determine the serialization logic between segments based on the overall arrangement relationship between the connecting segment and the reaction segment, and sort each advancement segment in a unified order according to the serialization logic and output the path segment set to obtain the stepwise synthesis reaction path segment set of emamectin benzoate.

[0035] After calling the connecting segment, a segment-by-segment comparison is performed on its overall arrangement relationship with the reaction segment structure. This action is accomplished by reading the sequential number of each reaction segment and sorting the segment numbers of the connecting segment in ascending order. For example, if the connecting segment corresponds to segment numbers 1, 3, 4, and 6, the adjacent difference of these numbers is judged. When the difference of the segment number is 1 or 2, it is considered to have serial logic. For example, the difference between segment 1 and 3 is 2 and the difference between segment 3 and 4 is 1, both of which meet the range. Then, the difference between the angle coordinates and the height coordinates of the contact interface between the segments is judged. When the angle difference is in the range of 3° to 11° and the height difference is in the range of 2mm to 8mm, the segment is considered to be able to complete the spatial connection. Then, the segments that can complete the connection are sorted in numerical order. The points inside each advancement segment are rearranged from low angle to high angle according to the advancement direction. Then, the continuity of the rearranged points is checked. When the angle of all points increases in one direction and the height increment does not decrease in the opposite direction, the segment is considered to be sorted. By performing the above actions on all segments in sequence, a complete advancement segment set can be formed.

[0036] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention should be included within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the scope of the claims.

Claims

1. A stepwise synthesis method for emamectin benzoate, characterized in that, Includes the following steps: S1: Observe the initial response of raw material touching the wall in the preheating start-up reaction section of abamectin, trace the path of raw material to the reaction chamber, extract the distribution band of thermal expansion traces and extend it to the inner wall propagation area, align the thermal trace extension interface at different times, separate the path band with the torsion point, and form the boundary trajectory line of raw material participation in the propagation. S2: Determine the regional boundary based on the trajectory line of the raw material participating in the advancement boundary, extend the heat trace path to the middle space, use the reaction phenomenon of the converted product in this space as a reference, select the continuous heat generation zone in the region, compare the reaction progress position and time, extract the path band related to the change of reactants, and form the intermediate conversion reaction distribution map line. S3: Call the intermediate conversion reaction distribution map line to mark the path zone, locate the reaction start point and end point of each path zone in sequence, compare the path changes and record the fluctuation segment, connect the path segments with frequent fluctuations in the degree of conversion, output the connecting zone continuously and unify it into a line to form a step-by-step reaction rhythm switching structure map line. S4: According to the step-by-step reaction rhythm, switch the path band in the structure diagram, map the main material and auxiliary material movement routes into the same space, observe the close sections of the two routes, identify the offset segments in the close area, adjust the starting entrance of the auxiliary material route and correct the direction, so that it keeps the previous trajectory consistent with the main material route, forming a material collaborative propulsion trajectory structure.

2. The stepwise synthesis reaction method of abamectin according to claim 1, characterized in that: The raw material participation in the advancement boundary trajectory line includes a heat distribution boundary layer, a boundary extension zone, and path segmentation nodes. The intermediate conversion reaction distribution path line includes a reaction evolution interval, a conversion characteristic zone, and an energy accumulation zone. The step-by-step reaction rhythm switching structure line specifically includes a rhythm partition sequence, a conversion connection point group, and a reaction step structure. The material collaborative advancement trajectory structure includes a route coupling transition zone, a collaborative matching section, and a synchronous advancement interface.

3. The stepwise synthesis reaction method of abamectin according to claim 1, characterized in that: The steps for obtaining the boundary trajectory line of the raw material are as follows: S101: Observe the initial response of the raw material to the wall in the preheating start-up reaction section of abamectin. Record the contact path based on the outer edge contour of the raw material, the heating morphology of the wall surface and the position of the contact point at the moment of contact. Based on these records, determine the continuous change of the outer edge of the adhesion zone to form the initial propagation zone of the contact and generate the contact propagation morphology characteristics. S102: The contact wall propagation morphology features are called to track the transfer path of the raw material to the reaction chamber. The path extension direction is determined according to the contact wall propagation morphology features, the direction of the wall heating traces and the outer edge movement trajectory. The heat expansion trace distribution zone is extracted to form the path extension interval, and the path extension interval features are obtained. S103: The path extension interval features are called to align the thermal trace extension interfaces at different times. The interface correspondence is determined based on the path extension interval features, the outer edge position of the thermal expansion trace distribution zone and the interface sequence. The torsion point is determined accordingly to separate and connect the path zone to form an overall propulsion interface, and the raw material participation propulsion boundary trajectory line is obtained.

4. The stepwise synthesis reaction method of abamectin according to claim 1, characterized in that: The steps for obtaining the intermediate conversion reaction distribution map are as follows: S201: Determine the region boundary based on the trajectory line of the raw material participating in the propulsion boundary, obtain the sequence of outer edge points of the trajectory line in space, determine the shape of the region boundary based on the positional relationship between the sequence of outer edge points and the wall of the reaction section, and establish the region boundary range accordingly. Extend the heat trace path to the middle section space within the range to generate the region boundary range interval. S202: Extend the heat trace path to the middle space by calling the area boundary range interval. Determine the continuous direction of the extended path in space according to the area boundary range interval, the arrangement relationship of the outer edge of the heat trace path and the arrangement order of the middle space position. Select the continuous heat generation zone according to the relationship between the extension direction and the position of the reaction phenomenon of the conversion product in the middle space to obtain the continuous heat generation zone sequence interval. S203: Call the continuous tropic zone sequence interval to compare the reaction progress position and time. Based on the continuous tropic zone sequence interval, the reaction progress time point, and the arrangement order of the tropic zones in the path, determine the correspondence between the path band and the reactant changes. Based on this, extract the corresponding path band from the sequence and connect them into a trajectory to obtain the intermediate conversion reaction distribution map.

5. The stepwise synthesis reaction method of abamectin according to claim 1, characterized in that: The steps for obtaining the step-by-step reaction rhythm switching structure diagram are as follows: S301: Call the intermediate conversion reaction distribution map line to mark the path band, obtain the path band edge point sequence in the map line, determine the position of the reaction start point and end point based on the continuous change of the edge point sequence in the path band, and record the fluctuation segment based on the path change between the start point and end point to generate the path fluctuation segment segment. S302: The path fluctuation segment is called to determine the order relationship between the fluctuation segments based on the adjacency relationship between the path fluctuation segment and the path band in the sequence, and the path segments with frequent fluctuations in the degree of transformation are connected adjacently according to the order relationship to form a continuous output band, thus obtaining a continuous output band segment. S303: Call the continuous output strip segments to determine the connection relationship between segments according to the arrangement order of the continuous output strip segments in the path strip sequence, and uniformly organize the connecting strips according to the connection relationship and output the continuous trajectory line to obtain the step-by-step reaction rhythm switching structure diagram line.

6. The stepwise synthesis reaction method of abamectin according to claim 1, characterized in that: The steps for obtaining the material cooperative propulsion trajectory structure are as follows: S401: Based on the path band in the step-by-step reaction rhythm switching structure diagram, the main material and auxiliary material movement routes are mapped into the same space, the corresponding point sequence of the two routes in the space is obtained, the proximity relationship of the corresponding point sequence in the space is used to determine the position of the proximity segment, and the offset segment is identified based on the position change of the proximity segment to generate the offset segment interval. S402: Call the offset segment interval to determine the entrance correction direction based on the relative position of the offset segment interval and the starting entrance of the auxiliary material route in space, and adjust the starting entrance of the auxiliary material route according to the judgment result so that the correction direction is consistent with the trajectory of the front section of the main material route, and obtain the entrance correction segment. S403: Call the inlet correction segment to determine the connection order of the two routes based on the corresponding positional relationship between the inlet correction segment and the main material route front section trajectory, and then organize and output the auxiliary material route correction segment and the main material route front section in a unified manner according to the connection order to obtain the material collaborative propulsion trajectory structure.

7. The stepwise synthesis reaction method of abamectin according to claim 1, characterized in that, Also includes: S5: Based on the path segments in the material collaborative propulsion trajectory structure, the main and auxiliary routes are simultaneously unfolded along the predetermined propulsion direction, and the reaction performance of each layer of material in the reaction section is laid out in sequence according to the propulsion direction. The path extension process is used to connect all reaction sections to form a set of stepwise synthesis reaction path segments of abamectin. The set of reaction pathway segments for the stepwise synthesis of abamectin specifically comprises a segment sequence framework, a stepwise partitioning system, and a set of advancement structures.

8. The stepwise synthesis reaction method of abamectin according to claim 7, characterized in that: The steps for obtaining the set of reaction pathway segments for the stepwise synthesis of abamectin are as follows: S501: Based on the path segments in the material collaborative propulsion trajectory structure, the main and auxiliary routes are simultaneously unfolded along the predetermined propulsion direction. The sequence of the main and auxiliary routes in the propulsion direction is obtained. The unfolding correspondence of the two routes is determined according to the front-to-back position relationship of the sequence of the points in the propulsion direction. Based on the correspondence, the reaction performance of each layer of material in the reaction section is unfolded in the propulsion direction in sequence to generate the propulsion unfolding segment. S502: The propulsion and spreading segment is invoked to determine the connection sequence of the path extension process based on the positional relationship between the propulsion and spreading segment and the path segment within the reaction segment, and the path segments are connected one by one according to the connection sequence so that they form a continuous extension flow between the reaction segments, thus obtaining a connected segment. S503: Call the connecting segment to determine the serialization logic between segments based on the overall arrangement relationship between the connecting segment and the reaction segment, and sort each advancement segment in a unified order according to the serialization logic and output the path segment set to obtain the stepwise synthesis reaction path segment set of emamectin benzoate.

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