Cell separation and extraction device for animal blood disease testing

By designing a servo motor-driven centrifugation assembly and an automatic extraction system, the problems of existing devices being unable to automatically extract cell fluid and process a single test tube at a time were solved. Stable clamping, automatic extraction, and multi-group data analysis were achieved, improving separation and extraction efficiency and detection accuracy.

CN122445455APending Publication Date: 2026-07-24ADV (QINGDAO) BIOTECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-15
Publication Date
2026-07-24

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Abstract

The present application relates to the technical field of blood extraction, in particular to a cell separation and extraction device for animal blood disease detection, which comprises a box body, a partition plate is arranged at the bottom of the box body, a cavity is formed between the box body and the partition plate, a centrifugal assembly is arranged in the cavity, and the centrifugal assembly is used for placing test tubes for centrifugal operation, the test tubes after centrifugation are taken out and replaced by collection test tubes, the piston rod at the end of the air cylinder drives the rack to reciprocate in the vertical direction, the rack drives the double-head gear rod to mesh and rotate in the moving process, the double-head gear rod drives the second wedge-shaped plate to reciprocate at a 90° angle in the rotating process, so that the second wedge-shaped plate reciprocally extrudes the first wedge-shaped plate, the air in the rubber head of the suction tube is continuously sprayed out, in the process of air spraying to generate airflow, the airflow pushes and extrudes the cell liquid temporarily stored in the glass tube of the suction tube, so that the cell liquid enters the collection test tube for collection, and the accuracy of animal pathological detection is improved.
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Description

Technical Field

[0001] This invention relates to the field of blood extraction technology, and in particular to a cell separation and extraction device for animal blood disease testing. Background Technology

[0002] Some congenital and acquired immunodeficiency diseases in animals, infections caused by certain pathogenic microorganisms, and malignant tumors are all related to reduced or deficient cellular immunity. In addition, the occurrence of tissue transplant rejection is also mainly due to the role of cellular immunity. Therefore, the study of cellular immunity is of great significance for the diagnosis, prevention, and treatment of the above-mentioned diseases. The body's immune response is mainly manifested by lymphocytes. In the study of cellular immunity, it is often necessary to isolate cells from the blood for research. Currently, microbial detection and analysis instruments are commonly used to extract and analyze cells from the blood.

[0003] There are many existing technologies for separation and extraction devices, such as: Chinese invention patent CN114874906A discloses a cell separation and extraction device for blood disease testing, including a sterile chamber. Inside the sterile chamber is a guide rod, with a threaded rod fixedly connected to the top of the guide rod. From top to bottom, the guide rod is sequentially fixedly connected to a fixing nut, an auxiliary plate, a limiting plate, and a fixing plate. This invention allows the operator to place the test tube into the through hole and hemispherical groove, maintaining the integrity of the test tube and facilitating cell extraction. The operator can adjust the bolts on the threaded rod to seal the test tube opening at any height, giving the centrifuge excellent flexibility. Furthermore, the combined use of the fixing block and sealing ball improves the operator's testing efficiency and prevents blood from flowing out of the test tube during centrifugation, thus improving the accuracy of the test results.

[0004] However, some problems still exist in actual use: Firstly, in actual operation, traditional separation and extraction components still require manual extraction of cell fluid after centrifugation, which cannot achieve automated extraction of cell fluid. This not only further increases the labor intensity of the operators, but also easily leads to a decrease in cell activity and loss of target cells due to delays or improper manual operation, thus affecting the separation and extraction effect. Secondly, existing devices can only centrifuge blood samples in a single test tube, and only one set of separation data can be obtained in a single operation. The data has obvious uniformity, which makes it difficult to meet the needs of simultaneous detection of batch samples and comparative analysis of multiple sets of data, further limiting the efficiency and practicality of separation and extraction operations. Summary of the Invention

[0005] In order to overcome the above-mentioned defects in the prior art, the present invention provides a cell separation and extraction device for animal blood disease testing.

[0006] To achieve the above objectives, the present invention provides a cell separation and extraction device for animal blood disease testing, comprising a housing with a partition at the bottom, forming a cavity between the housing and the partition, and a centrifugation assembly within the cavity. The centrifugation assembly is used to hold test tubes for centrifugation. The centrifugation assembly includes a servo motor located at the bottom of the housing, with its output end penetrating the housing into the cavity and having a main gear at its end. Secondary gears mesh with the main gear on its side, and the secondary gears are arranged in an array. Each secondary gear has a placement box at its top, into which test tubes are placed. Clamping components are located on both sides of the placement box. A sealing assembly is located inside the housing to seal the top of the rotating test tubes. An extraction assembly is located at the top of the sealing assembly to extract the cell fluid after centrifugation.

[0007] Furthermore, the clamping assembly includes cylindrical columns disposed on both sides of the placement box, a sliding rod slidably disposed on the inner wall of the cylindrical column, a clamping plate disposed at the end of the sliding rod, an elastic element disposed between the cylindrical column and the sliding rod, and a guide plate disposed on the top of the clamping plate.

[0008] Furthermore, a groove is provided at the bottom of the column, a slider is provided at the end of the slider rod, the slider slides on the inner wall of the groove, and a limiting groove is provided at the bottom of the slider.

[0009] Furthermore, the outer wall of the placement box is provided with a support plate, the surface of the support plate is provided with a telescopic rod, the top of the telescopic rod is provided with a base plate, a compression spring is provided between the telescopic rod and the base plate, the top of the base plate is provided with a limiting block, and the limiting block is adapted to the limiting groove provided at the bottom of the slider.

[0010] Furthermore, the sealing assembly includes a rotating motor located at the top of the housing, the output shaft of the rotating motor passing through the housing and having a lead screw at its end, a movable block on the surface of the lead screw, a hollow frame on the side wall of the movable block, the hollow frame corresponding to the placement box, and a sealing cover at the bottom of the hollow frame.

[0011] Furthermore, a straw is provided inside the hollow frame. The straw consists of a rubber head and a glass tube, and a drip groove is formed on the surface of the glass tube.

[0012] Furthermore, the straw is provided with a first wedge plate at the top, and limiting rods are provided on both sides of the first wedge plate. The limiting rods pass through the hollow frame, and limiting springs are provided on the surface of the limiting rods. The two ends of the limiting springs are respectively connected to the hollow frame and the first wedge plate.

[0013] Furthermore, the extraction component includes a second wedge plate disposed above the first wedge plate. The top of the second wedge plate passes through the hollow frame and has a rotating gear at its end. During the rotation of the second wedge plate, it presses down on the top of the first wedge plate.

[0014] Furthermore, the rotating gear is provided with double-headed gear rods on both sides, and a rack is provided on one side of the double-headed gear rods. A cylinder is provided below the rack, and the piston rod at the end of the cylinder drives the rack to reciprocate in the vertical direction.

[0015] Compared with the prior art, the beneficial effects of the present invention are as follows: 1. In this cell separation and extraction device for animal blood disease testing, the base plate is pressed down vertically. When the test tube is inserted between the clamps, the test tube squeezes the clamps during insertion, causing the slide bar to slide on the inner wall of the cylinder. When the test tube is placed, the pressing of the base plate stops, and the base plate is reset by the restoring force of the compression spring. This causes the base plate to move 208 vertically upward and limit and fix the limiting groove at the bottom of the slider, keeping the test tube clamped between the clamps stable during centrifugation, preventing the test tube from shaking during rotation, and improving the efficiency of cell separation and extraction.

[0016] 2. In this cell separation and extraction device for animal blood disease testing, the output end of the rotating motor drives the lead screw to rotate. During the rotation of the lead screw, the moving block moves vertically, and the moving block moves the hollow frame downward until the sealing cover located below the hollow frame fits against the top of the test tube. When the output shaft of the servo motor drives the main gear to rotate, the secondary gear drives the placement box to mesh and rotate, causing the test tubes held inside the placement box to rotate and centrifuge. The sealing cover covers the top of the test tubes to prevent the animal blood inside the test tubes from splashing, thereby preventing the cell separation operation environment from being contaminated and improving the safety of the separation operation.

[0017] 3. In this cell separation and extraction device for animal blood disease testing, the centrifuged test tubes are removed and replaced with collection test tubes to collect cell fluid. The piston rod at the end of the cylinder drives a rack to reciprocate vertically. During this movement, the rack drives a double-headed gear rod to rotate. This rotation causes the second wedge plate to reciprocate at a 90° angle, resulting in the second wedge plate repeatedly squeezing the first wedge plate. This causes air to be continuously ejected from the pipette head. The airflow pushes the temporarily stored cell fluid in the glass tube of the pipette, allowing it to enter the collection test tube for collection. By mixing the cell fluid from multiple collection test tubes and analyzing it using testing equipment, the pathological causes of the animal can be determined, improving the accuracy of animal pathological testing. Attached Figure Description

[0018] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0019] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2This is a cross-sectional view of the overall structure of the present invention; Figure 3 This is a schematic diagram of the centrifuge assembly structure of the present invention; Figure 4 This is a cross-sectional view of the clamping component of the present invention; Figure 5 For the present invention Figure 4 Schematic diagram at point A; Figure 6 This is a schematic diagram of the sealing assembly structure of the present invention; Figure 7 This is a schematic diagram of the extraction component structure of the present invention; Figure 8 This is the main view of the extraction component of the present invention.

[0020] The meanings of the labels in the diagram are as follows: 100. Box body; 101. Partition; 200. Centrifuge assembly; 201. Servo motor; 202. Main gear; 203. Secondary gear; 204. Placement box; 205. Telescopic rod; 206. Compression spring; 207. Base plate; 208. Limiting block; 300. Clamping assembly; 301. Column; 302. Slide bar; 303. Clamping plate; 304. Elastic element; 305. Slide groove; 306. Slider; 400. Sealing assembly; 401. Rotary motor; 402. Lead screw; 403. Moving block; 404. Hollow frame; 405. Sealing cover; 406. Straw; 407. Drip groove; 408. First wedge plate; 409. Limiting rod; 410. Limiting spring; 500. Extraction component; 501. Second wedge plate; 502. Rotating gear; 503. Double-ended gear rod; 504. Rack; 505. Cylinder. Detailed Implementation

[0021] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0022] A cell separation and extraction device for animal blood disease testing, based on Figure 1-8As shown, the device includes a housing 100, with a partition 101 at the bottom of the housing 100, forming a cavity between the housing 100 and the partition 101. A centrifuge assembly 200 is located within the cavity, used for holding test tubes for centrifugation. The centrifuge assembly 200 includes a servo motor 201 located at the bottom of the housing 100. The output end of the servo motor 201 extends through the housing 100 into the cavity and has a main gear 202 at its end. A secondary gear 203 meshes with the side of the main gear 202, and the secondary gears 203 are arranged in an array. Each secondary gear 203 has a placement box 204 on its top, where test tubes are placed. Clamping assemblies 300 are located on both sides of the placement box 204. A sealing assembly 400 is located inside the housing 100, used to seal the top of the rotating test tubes. An extraction assembly 500 is located on the top of the sealing assembly 400, used to extract the cell fluid after centrifugation.

[0023] When centrifuging blood in test tubes, to facilitate quick clamping and fixing of the test tubes, the clamping assembly 300 includes a cylindrical tube 301 on both sides of the placement box 204. A sliding rod 302 is slidably provided on the inner wall of the cylindrical tube 301, and a clamping plate 303 is provided at the end of the sliding rod 302. An elastic element 304 is provided between the cylindrical tube 301 and the sliding rod 302. A guide plate is provided on the top of the clamping plate 303. By pressing the sliding rod 302, it slides against the inner wall of the cylindrical tube 301. During the sliding process, the sliding rod 302 squeezes the elastic element 304, thereby increasing the gap between the clamping plates 303. When the test tube is placed between the clamping plates 303 and the squeezing of the sliding rod 302 stops, the sliding rod 302 is reset by the force of the elastic element 304, causing the sliding rod 302 to drive the clamping plate 303 to move in the opposite direction until the end face of the clamping plate 303 is in contact with the outer wall of the test tube, thus achieving rapid positioning of the test tube. During centrifugation of the test tubes, the centrifugal force compresses the clamping plates 303, causing the test tubes, which are held and limited between the clamping plates 303, to shake, affecting the efficiency of cell separation and extraction. Therefore, a groove 305 is provided at the bottom of the column cylinder 301, and a slider 306 is provided at the end of the sliding rod 302. The slider 306 slides on the inner wall of the groove 305, and a limiting groove is provided at the bottom of the slider 306. A support plate is provided on the outer wall of the placement box 204, and a telescopic rod 205 is provided on the surface of the support plate. A base plate 207 is provided on the top of the telescopic rod 205, and a compression spring 206 is provided between the telescopic rod 205 and the base plate 207. A limiting block 208 is provided on the top of the base plate 207, and the limiting block 208 is adapted to the limiting groove provided at the bottom of the slider 306. By controlling the output shaft of the servo motor 201, the main gear 202 is driven to rotate, and the secondary gear 203 provided on one side of the main gear 202 meshes and rotates. The placement box 204 is provided on the top of the secondary gear 203. 4. Coaxial rotation: When placing the test tube, press the base plate 207 to move it downwards in the vertical direction. When the test tube is inserted between the clamping plates 303, the test tube squeezes the clamping plates 303 during insertion, causing the slide rod 302 to slide on the inner wall of the cylinder 301. When the limiting is completed, stop squeezing the base plate 207. The base plate 207 is reset by the restoring force of the compression spring 206, causing the base plate 207 to drive the limiting block 208 to move upwards in the vertical direction and limit and fix the limiting groove at the bottom of the slider 306. This keeps the test tube clamped between the clamping plates 303 stable during centrifugation, preventing the test tube from shaking during rotation and improving the efficiency of cell separation and extraction. When the centrifugation is completed, press the base plate 207 again, causing the base plate 207 to drive the limiting block 208 to move downwards in the vertical direction. The limiting block 208 moves away from the limiting groove at the bottom of the slider 306, making it easier to remove the centrifuged test tube.

[0024] To prevent blood from splashing and contaminating the environment during centrifugation of test tubes, the sealing assembly 400 includes a rotary motor 401 located at the top of the housing 100. The output shaft of the rotary motor 401 passes through the housing 100 and has a lead screw 402 at its end. A movable block 403 is provided on the surface of the lead screw 402, and a hollow frame 404 is provided on the side wall of the movable block 403. The hollow frame 404 corresponds one-to-one with the placement box 204, and a sealing cover 405 is provided at the bottom of the hollow frame 404. By controlling the output end of the rotary motor 401 to drive the lead screw 402 to rotate, the lead screw 402 rotates... During the process, the moving block 403 moves vertically, and the moving block 403 moves the hollow frame 404 downward until the sealing cover 405 below the hollow frame 404 fits against the top of the test tube. When the output shaft of the servo motor 201 drives the main gear 202 to rotate, the secondary gear 203 drives the placement box 204 to mesh and rotate, so that the test tube clamped inside the placement box 204 rotates for centrifugation. The sealing cover 405 covers the top of the test tube to prevent the animal blood inside the test tube from splashing out, thereby preventing the cell separation operation environment from being contaminated and improving the safety of the separation operation.

[0025] To quickly extract the separated cell fluid after centrifugation of the blood test tube, a pipette 406 is installed inside the hollow frame 404. The pipette 406 consists of a rubber head and a glass tube. A drip groove 407 is formed on the surface of the glass tube. A first wedge plate 408 is provided at the top of the pipette 406. Limiting rods 409 are provided on both sides of the first wedge plate 408. The limiting rods 409 pass through the hollow frame 404. A limiting spring 410 is provided on the surface of the limiting rods 409. The two ends of the limiting spring 410 are connected to the hollow frame 404 and the first wedge plate 408, respectively. By pressing the first wedge plate 408, the lower part of the first wedge plate 408... The rubber head is squeezed to expel air. During the downward movement of the first wedge plate 408, the limiting rod 409 slides on the inner wall of the hollow frame 404 and squeezes the limiting spring 410. After the air inside the rubber head is expelled, the squeezing of the rubber head of the pipette 406 stops. Since the rubber head is in a negative pressure state, when it is necessary to extract cell fluid, the pressing of the first wedge plate 408 stops. The first wedge plate 408 is reset by the force of the limiting spring 410. At this time, the glass tube of the pipette 406 absorbs the cell fluid in the test tube, thereby releasing the negative pressure state of the rubber head and realizing the rapid extraction of cell fluid.

[0026] During the cell fluid extraction process, operators need to press the first wedge plate 408 to facilitate automatic extraction of the cell fluid after centrifugation. This results in high labor intensity for the operators. Therefore, the extraction component 500 includes a second wedge plate 501 positioned above the first wedge plate 408. The top of the second wedge plate 501 penetrates the hollow frame 404, and a rotating gear 502 is provided at its end. During rotation, the second wedge plate 501 presses the top of the first wedge plate 408, and the rotating gear 502 drives the second wedge plate. When the second wedge plate 501 rotates to 90°, it squeezes the first wedge plate 408 during the rotation of the second wedge plate 501. When the rotating gear 502 rotates to 90°, the air inside the rubber head of the pipette 406 is discharged and a negative pressure state is formed. The hollow frame 404 is controlled to move the sealing cap 405 to the top of the test tube. When the centrifugation operation of the test tube is completed, the rotating gear 502 is rotated in the opposite direction to reset, thereby releasing the pressure of the second wedge plate 501 on the first wedge plate 408, allowing the pipette 406 to absorb and extract the cell fluid, reducing the labor intensity of the operators.

[0027] To improve testing accuracy, animal blood is dripped into multiple test tubes. The output shaft of the servo motor 201 drives the main gear 202 to rotate, causing the secondary gear 203 on the side of the main gear 202 to mesh and rotate. This causes the placement box 204 on top of the secondary gear 203 to rotate coaxially, achieving centrifugation. After centrifugation, cell fluid is extracted using a pipette 406. To quickly mix the extracted cell fluid in the pipette 406, double-headed gear rods 503 are located on both sides of the rotating gear 502. A rack 504 is located on one side of the double-headed gear rod 503, and a cylinder 505 is located below the rack 504. The piston rod at the end of the cylinder 505 drives the rack 504 to reciprocate vertically. By removing the centrifuged test tubes and replacing them with collection test tubes for collecting cell fluid, the cylinder is controlled... The piston rod at the end of 505 drives the rack 504 to reciprocate vertically. During the movement, the rack 504 drives the double-headed gear rod 503 to mesh and rotate. During the rotation of the double-headed gear rod 503, the second wedge plate 501 rotates at a 90° angle, thereby causing the second wedge plate 501 to reciprocate and squeeze the first wedge plate 408, causing the air in the rubber head of the pipette 406 to be continuously ejected. During the airflow generated by the air ejection, the airflow pushes the cell fluid temporarily stored in the glass tube of the pipette 406, causing the cell fluid to enter the collection test tube for collection. By mixing the cell fluid in multiple collection test tubes and analyzing the cell fluid through testing equipment, the cause of animal pathology can be obtained, meeting the needs of simultaneous detection of batch samples and comparative analysis of multiple sets of data, and improving the accuracy of animal pathology detection.

[0028] In practical use, when placing a test tube containing blood, the base plate 207 is pressed to move it downwards in the vertical direction. When the test tube is inserted between the clamping plates 303, the test tube squeezes the clamping plates 303 during insertion, causing the slide bar 302 to slide on the inner wall of the cylinder 301. When the limiting is completed, the squeezing of the base plate 207 stops, and the base plate 207 is reset by the restoring force of the compression spring 206. This causes the base plate 207 to drive the limiting block 208 to move upwards in the vertical direction and limit and fix the limiting groove at the bottom of the slider 306, so that the test tube held between the clamping plates 303 remains stable during centrifugation. When the output shaft of the servo motor 201 drives the main gear 202 to rotate, the secondary gear 203 drives the placement box 204 to mesh and rotate, preventing the test tube from shaking during rotation and improving the efficiency of cell separation and extraction. The output of the rotating motor 401 drives the lead screw 402 to rotate. During the rotation of the lead screw 402, the moving block 403 moves vertically. During the movement of the moving block 403, the hollow frame 404 moves downward until the sealing cover 405 located below the hollow frame 404 fits against the top of the test tube. When the output shaft of the servo motor 201 drives the main gear 202 to rotate, the secondary gear 203 drives the placement box 204 to mesh and rotate, causing the test tube clamped inside the placement box 204 to rotate for centrifugation. The sealing cover 405 covers the top of the test tube to prevent the animal blood inside the test tube from splashing out, thereby preventing the cell separation operation environment from being contaminated and improving the safety of the separation operation. By controlling the piston rod at the end of the cylinder 505, the rack 504 is moved vertically. When the rack 504 moves, it drives the double-headed gear rod 503 to mesh and rotate. The double-headed gear rod 503 drives the rotating gear 502 to mesh and rotate. When the rotating gear 502 drives the second wedge plate 501 to rotate to 90°, the second wedge plate 501 squeezes the first wedge plate 408 during rotation. When the rotating gear 502 rotates to 90°, the air inside the rubber head of the pipette 406 is discharged and a negative pressure state is formed. The hollow frame 404 is controlled to drive the sealing cap 405 to move to the top of the test tube. When the centrifugation operation of the test tube is completed, the rotating gear 502 is rotated in the opposite direction to reset, so that the second wedge plate 501 releases the pressure on the first wedge plate 408, allowing the pipette 406 to absorb and extract the cell fluid, reducing the labor intensity of the operators. After centrifugation, the test tubes are removed and replaced with collection test tubes for collecting cell fluid. The piston rod at the end of cylinder 505 drives rack 504 to reciprocate vertically. During this movement, rack 504 drives double-headed gear rod 503 to mesh and rotate. The rotation of double-headed gear rod 503 causes second wedge plate 501 to reciprocate at a 90° angle, thus causing second wedge plate 501 to reciprocate and compress first wedge plate 408. This causes air to continuously spray out from the rubber head of pipette 406. During the airflow, the air pushes the temporarily stored cell fluid in the glass tube of pipette 406, allowing the cell fluid to enter the collection test tube for collection. This reduces the labor intensity of operators. By mixing the cell fluid from multiple collection test tubes and analyzing the cell fluid using testing equipment, the cause of animal pathology can be determined, improving the accuracy of animal pathology testing.

[0029] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the present invention as claimed. The scope of protection of the present invention is defined by the appended claims and their equivalents.

Claims

1. A cell separation and extraction device for animal blood disease testing, characterized in that: The device includes a housing (100), with a partition (101) at the bottom. A cavity is formed between the housing (100) and the partition (101), and a centrifuge assembly (200) is provided inside the cavity. The centrifuge assembly (200) is used for placing test tubes for centrifugation. The centrifuge assembly (200) includes a servo motor (201) located at the bottom of the housing (100). The output end of the servo motor (201) extends through the housing (100) into the cavity, and a main gear (202) is provided at its end. A secondary gear is meshed on the side of the main gear (202). (203), the secondary gears (203) are arranged in an array, and each secondary gear (203) is provided with a placement box (204) on its top. The placement box (204) is used to place test tubes. The placement box (204) is provided with clamping components (300) on both sides. The box body (100) is provided with a sealing component (400). The sealing component (400) is used to seal the top of the rotating test tube. The sealing component (400) is provided with an extraction component (500) on its top. The extraction component (500) is used to extract the cell fluid after centrifugation.

2. The cell separation and extraction device for animal blood disease testing according to claim 1, characterized in that, The clamping assembly (300) includes a cylindrical tube (301) disposed on both sides of the placement box (204), a sliding rod (302) is slidably disposed on the inner wall of the cylindrical tube (301), a clamping plate (303) is disposed at the end of the sliding rod (302), an elastic element (304) is disposed between the cylindrical tube (301) and the sliding rod (302), and a guide plate is disposed on the top of the clamping plate (303).

3. The cell separation and extraction device for animal blood disease testing according to claim 2, characterized in that, The bottom of the column (301) is provided with a sliding groove (305), and the end of the sliding rod (302) is provided with a slider (306). The slider (306) slides on the inner wall of the sliding groove (305), and the bottom of the slider (306) is provided with a limiting groove.

4. The cell separation and extraction device for animal blood disease testing according to claim 3, characterized in that, The outer wall of the placement box (204) is provided with a support plate, and the surface of the support plate is provided with a telescopic rod (205). The top of the telescopic rod (205) is provided with a base plate (207). A compression spring (206) is provided between the telescopic rod (205) and the base plate (207). The top of the base plate (207) is provided with a limiting block (208). The limiting block (208) is adapted to the limiting groove provided at the bottom of the slider (306).

5. The cell separation and extraction device for animal blood disease testing according to claim 3, characterized in that, The sealing assembly (400) includes a rotating motor (401) located on the top of the housing (100). The output shaft of the rotating motor (401) passes through the housing (100) and has a lead screw (402) at its end. A moving block (403) is provided on the surface of the lead screw (402). A hollow frame (404) is provided on the side wall of the moving block (403). The hollow frame (404) corresponds one-to-one with the placement box (204). A sealing cover (405) is provided at the bottom of the hollow frame (404).

6. The cell separation and extraction device for animal blood disease testing according to claim 5, characterized in that, The hollow frame (404) is provided with a straw (406) inside. The straw (406) consists of a rubber head and a glass tube, and a drip groove (407) is opened on the surface of the glass tube.

7. The cell separation and extraction device for animal blood disease testing according to claim 6, characterized in that, The straw (406) is provided with a first wedge plate (408) at the top, and a limiting rod (409) is provided on both sides of the first wedge plate (408). The limiting rod (409) passes through the hollow frame (404), and a limiting spring (410) is provided on the surface of the limiting rod (409). The two ends of the limiting spring (410) are respectively connected to the hollow frame (404) and the first wedge plate (408).

8. The cell separation and extraction device for animal blood disease testing according to claim 1, characterized in that, The extraction component (500) includes a second wedge plate (501) disposed above the first wedge plate (408). The top of the second wedge plate (501) passes through the hollow frame (404) and the end is provided with a rotating gear (502). During the rotation of the second wedge plate (501), it presses the top of the first wedge plate (408).

9. The cell separation and extraction device for animal blood disease testing according to claim 8, characterized in that, The rotating gear (502) is provided with double-headed gear rods (503) on both sides, and a rack (504) is provided on one side of the double-headed gear rod (503). A cylinder (505) is provided below the rack (504), and the piston rod at the end of the cylinder (505) drives the rack (504) to reciprocate in the vertical direction.

Citation Information

Patent Citations

  • Cell separation and extraction device for blood disease examination

    CN114874906A