A lutein ester microcapsule coated mobile phone film and a preparation method thereof

Abstract

The application belongs to the technical field of mobile phone screen protection film, and discloses a lutein ester microcapsule coating mobile phone film and a preparation method thereof. The lutein ester microcapsule coating mobile phone film comprises a substrate layer and a functional coating arranged on the substrate layer, and the functional coating comprises lutein ester microcapsules. The application further discloses an application of the lutein ester microcapsule coating mobile phone film in reducing oxidative stress damage of human epidermal tissue caused by electronic screen light and a preparation method thereof. The nematode experiment shows that the protection effect of the application is not dependent on visual pathways and material contact transfer, the lutein ester microcapsule coating is used to modify the transmitted screen light, the ability of the transmitted light to induce skin cells to produce active oxygen is reduced, and thus skin light protection is achieved.

Description

Technical Field

[0001] This invention relates to the field of mobile phone screen protector technology, and in particular to a lutein ester microcapsule coated mobile phone film and its preparation method. Background Technology

[0002] With the widespread use of smartphones, people are spending significantly more time in front of electronic screens every day. The light emitted from mobile phone screens (especially blue light) not only poses a threat to visual health, but recent studies have also found that screen light can damage the user's facial skin. Research shows that visible light can induce skin cells to produce reactive oxygen species (ROS), thereby triggering oxidative stress responses, leading to skin aging and pigmentation. Electronic screen light has been identified as another important exogenous oxidative stress inducing factor for the skin, following ultraviolet radiation.

[0003] Currently, most mobile phone screen protectors on the market focus on protecting users' eyes, lacking the function of protecting against oxidative stress damage to human epidermal tissue caused by screen light. The functional coatings of existing mobile phone screen protectors are all inert materials (such as PET resin, blue light absorbers, anti-fouling and antioxidant compositions, etc.), and their function is limited to physical protection or optical modulation, without active biological protection function. Therefore, there is an urgent need for a mobile phone screen protector product that can break through the traditional optical filtering approach and protect the skin from light damage. Summary of the Invention

[0004] The present invention aims to provide a lutein ester microcapsule coated mobile phone film and its preparation method, so as to solve the problem that the existing technology relies only on the visual pathway for photoprotection and cannot provide photoprotection for the skin.

[0005] To achieve the above objectives, the present invention provides the following technical solution:

[0006] A lutein ester microcapsule coated mobile phone film includes a substrate layer and a functional coating, wherein the functional coating is disposed on the substrate layer and contains lutein ester microcapsules.

[0007] Furthermore, the functional coating is a coating formed by coating a lutein ester microcapsule solution onto a substrate layer, wherein the concentration of the lutein ester microcapsule solution is 0.1% to 0.5%.

[0008] Furthermore, a polyvinyl alcohol base coating is provided between the substrate layer and the functional coating.

[0009] Furthermore, the thickness of the functional coating is 5–20 μm.

[0010] The present invention also provides the application of the above-mentioned lutein ester microcapsule coated mobile phone film in reducing oxidative stress damage to human epidermal tissue caused by electronic screen light.

[0011] This invention also provides a method for preparing the above-mentioned lutein ester microcapsule coated mobile phone film, comprising the following steps:

[0012] S1: Apply a polyvinyl alcohol solution to the substrate layer, dry and cure to form a base coating;

[0013] S2: Apply lutein ester microcapsule solution onto the base coating and let it dry to form a functional coating.

[0014] Furthermore, in step S1, the concentration of the polyvinyl alcohol solution is 0.5% to 2%, and the drying temperature is 50 to 70°C.

[0015] Furthermore, in step S2, the concentration of the lutein ester microcapsule solution is 0.1% to 0.5%, and it is naturally air-dried at 15 to 25°C.

[0016] Furthermore, in steps S1 and S2, a wire bar coater is used for coating, and the thickness of each coating layer is 5 to 15 μm.

[0017] The principles and beneficial effects of the technical solution are as follows:

[0018] 1. This invention is the first to apply lutein ester microcapsules to mobile phone film coatings, providing a novel approach to skin protection against screen light. By setting a functional coating containing lutein ester microcapsules on the surface of the mobile phone film, the absorption characteristics of lutein esters for specific wavelengths of light and the free radical quenching ability unique to carotenoids are utilized to reduce the ability of transmitted light to induce ROS production in skin cells, thus achieving photobiological protection. This is a completely new dimension of protection, distinct from simply reducing the amount of light. The above-mentioned photomodification mechanism was verified through experiments with Caenorhabditis elegans. The nematodes have no visual organs and did not come into contact with the film surface during the experiment. The experimental results showed a significant reduction in ROS levels and a significant improvement in mobility, proving that the protective effect of this invention does not depend on the visual pathway or the material transfer of the active ingredients, but is achieved through the modification of transmitted light.

[0019] 2. By preparing lutein esters into microcapsule form, the activity of lutein esters is effectively protected, enabling them to maintain stable photophysical functions in mobile phone film coatings.

[0020] 3. The preparation of mobile phone screen protectors can be completed in two steps: a polyvinyl alcohol base coating and a lutein ester microcapsule solution coating. The screen protector can be air-dried at room temperature. The operation is simple and does not require complicated equipment. Attached Figure Description

[0021] Figure 1 This is a comparison chart showing the movement ability (oscillation frequency) of nematodes covered with the lutein ester microcapsule coating of this invention and nematodes covered with ordinary mobile phone films under the illumination of a mobile phone screen.

[0022] Figure 2A comparison of fluorescence detection of reactive oxygen species (ROS) levels in nematodes.

[0023] Figure 3 The graph shows a comparison of the light transmittance of the lutein ester microcapsule coated mobile phone film of the present invention and ordinary mobile phone films at different wavelengths; wherein:

[0024] Figure 3 A is a comparison chart of transmittance at a wavelength of 430nm;

[0025] Figure 3 B is a comparison chart of transmittance at a wavelength of 550nm. Detailed Implementation

[0026] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments:

[0027] Example 1:

[0028] This embodiment provides a method for preparing a lutein ester microcapsule coated mobile phone film, including the following steps:

[0029] S1. Preparation of the base coating: Using a wire bar coater (10μm), a 1% polyvinyl alcohol (PVA) solution is uniformly coated onto the surface of the substrate layer (PET film), and then dried in a 60℃ oven to form a polyvinyl alcohol base coating.

[0030] S2. Preparation of functional coating: Using a wire bar coater (10μm), a 0.2% lutein ester microcapsule solution is uniformly coated on the surface of the base coating obtained in step S1. The coating is then air-dried at 20℃ to form a functional coating, which is the lutein ester microcapsule coated mobile phone film.

[0031] Measurements showed that the dry film thickness of the obtained functional coating was approximately 5–20 μm.

[0032] The lutein ester microcapsules used in this embodiment were prepared using conventional methods in the art. Specifically, lutein ester was mixed with wall materials such as sodium octenyl succinate starch and maltodextrin in appropriate proportions, and deionized water was added to prepare a solution. After high-speed shear emulsification and high-pressure homogenization, the solution was spray-dried to obtain lutein ester microcapsule powder. Since this microcapsule preparation method is well-known in the art, this invention does not impose any particular limitations on it.

[0033] Example 2: Measurement of Nematode Motility

[0034] This embodiment uses *C. elegans* as a model organism. *C. elegans* lacks visual organs, meaning it has no visual pathway to receive light. Light directly affects the entire body of *C. elegans*, thereby evaluating the impact of screen light on the skin surface and the protective effect of the lutein ester microcapsule coating mobile phone film of this invention.

[0035] The experiment employed a non-contact design: the phone screen was fixed face down above the nematode, allowing the screen light to shine vertically onto the nematode, while maintaining a distance between the membrane and the nematode to prevent direct contact.

[0036] Experimental group: The surface of the mobile phone screen was covered with the lutein ester microcapsule coating prepared in Example 1 of this invention. The mobile phone screen was kept on and continuously irradiated at the nematodes.

[0037] Control group: The surface of the mobile phone screen was covered with a regular mobile phone film (without lutein ester microcapsule coating), the mobile phone screen was kept on, and the nematodes were continuously irradiated.

[0038] Under the same environment, the wiggling frequency (motor ability) of two groups of nematodes was measured. The wiggling frequency of nematodes mainly represents their motor ability and the functional state of their neuromuscular system. It is a core behavioral indicator for assessing the health, aging process and drug toxicity of nematodes.

[0039] The measurement results are as follows Figure 1 As shown, under continuous illumination from a mobile phone screen, the nematodes in the experimental group covered with the lutein ester microcapsule coating mobile phone film of the present invention exhibited a significantly higher oscillation frequency than the nematodes in the control group covered with a regular mobile phone film. The above results indicate that the lutein ester microcapsule coating mobile phone film prepared in Example 1 can alleviate the damage to organisms caused by mobile phone screen light, effectively protect the neuromuscular function of nematodes, and provide non-contact skin light damage protection without relying on the visual pathway.

[0040] Example 3: Measurement of Reactive Oxygen Species (ROS) Levels in Nematodes

[0041] Using the same experimental conditions as in Example 2, after irradiating the two groups of nematodes for the same amount of time, the reactive oxygen species levels in the nematodes were detected using a ROS fluorescent probe.

[0042] The measurement results are as follows Figure 2 As shown, the control group nematodes exhibited strong ROS fluorescence signals, indicating that mobile phone screen light irradiation induced a significant oxidative stress response; while the experimental group nematodes showed significantly weaker ROS fluorescence signals than the control group, indicating that the lutein ester microcapsule coated mobile phone film of the present invention can effectively reduce the ROS level of nematodes under screen light irradiation.

[0043] Since *Caenorhabditis elegans* lacks visual organs and the nematodes did not contact the membrane surface during the experiment, the above results indicate that the protective effect of the lutein ester microcapsule-coated mobile phone film of this invention does not depend on the visual pathway or on the material transfer of the active ingredient, but is achieved by modifying the transmitted light as it passes through the coating. The ROS data of this embodiment corroborate the movement ability data of Example 2, jointly demonstrating that the lutein ester microcapsule-coated mobile phone film of this invention has a significant protective effect against photodamage to the skin.

[0044] Example 4: Transmittance Measurement

[0045] The transmittance of the lutein ester microcapsule coated mobile phone film prepared in Example 1 and the ordinary mobile phone film (without lutein ester microcapsule coating) at different wavelengths were measured using a spectrophotometer.

[0046] The measurement results are as follows Figure 3 As shown, at a wavelength of 430 nm, the light transmittance of the lutein ester microcapsule coated mobile phone film of the present invention is significantly lower than that of ordinary mobile phone films. Figure 3 A) indicates that the coating of the present invention can effectively reduce the transmittance of harmful blue light bands; at a wavelength of 550nm, there is no significant difference in transmittance between the mobile phone film of the present invention and ordinary mobile phone films. Figure 3 (B) indicates that the coating of the present invention does not affect the transmission of normal visible light and will not affect the screen display effect. The above results show that the coating of the present invention, while achieving protection against skin photodamage, also has a certain function of filtering harmful blue light, which can help reduce the potential impact of blue light on the user's eyes, but does not rely on this optical filtering effect to achieve its skin protection effect.

[0047] Example 5: Verification of process parameters

[0048] Following the method of Example 1, mobile phone films were prepared using the following parameters, all of which resulted in the formation of a uniform functional coating. The obtained mobile phone films showed a significant reduction effect on ROS in nematodes (verification method same as in Example 3).

[0049] The mass fractions of the polyvinyl alcohol solution were 0.5%, 1%, and 2%, respectively, and the drying temperatures were 50℃, 60℃, and 70℃, respectively. The mass fractions of the lutein ester microcapsule solution were 0.1%, 0.2%, and 0.5%, respectively, and the air-drying temperatures were 15℃, 20℃, and 25℃, respectively. The coating thicknesses were 5μm, 10μm, and 15μm, respectively.

[0050] The results show that, within the above parameter range, the present invention can obtain lutein ester microcapsule coated mobile phone films with stable coating structure and significant ROS reduction effect.

[0051] The above descriptions are merely embodiments of the present invention, and common knowledge regarding specific technical solutions or characteristics is not elaborated upon here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the technical solutions of the present invention, and these should also be considered within the scope of protection of the present invention. These modifications and improvements will not affect the effectiveness of the implementation of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A lutein ester microcapsule coated mobile phone film, characterized in that: It includes a substrate layer and a functional coating, wherein the functional coating is disposed on the substrate layer and contains lutein ester microcapsules.

2. The lutein ester microcapsule coated mobile phone film according to claim 1, characterized in that: The functional coating is a coating formed by coating a lutein ester microcapsule solution onto the substrate layer, wherein the concentration of the lutein ester microcapsule solution is 0.1% to 0.5%.

3. The lutein ester microcapsule coated mobile phone film according to claim 1, characterized in that: A polyvinyl alcohol base coating is also provided between the substrate layer and the functional coating.

4. The lutein ester microcapsule coated mobile phone film according to claim 1, characterized in that: The thickness of the functional coating is 5–20 μm.

5. The application of the lutein ester microcapsule coated mobile phone film according to any one of claims 1-4 in reducing oxidative stress damage to human epidermal tissue caused by electronic screen light.

6. A method for preparing a lutein ester microcapsule coated mobile phone film according to any one of claims 1-4, characterized in that, Includes the following steps: S1: Apply a polyvinyl alcohol solution to the substrate layer, dry and cure to form a base coating; S2: Apply lutein ester microcapsule solution onto the base coating and let it dry to form a functional coating.

7. The method for preparing a lutein ester microcapsule coated mobile phone film according to claim 6, characterized in that: In step S1, the concentration of the polyvinyl alcohol solution is 0.5% to 2%, and the drying temperature is 50 to 70°C.

8. The method for preparing a lutein ester microcapsule coated mobile phone film according to claim 6, characterized in that: In step S2, the concentration of the lutein ester microcapsule solution is 0.1% to 0.5%, and it is naturally air-dried at 15 to 25°C.

9. The method for preparing the lutein ester microcapsule coated mobile phone film according to claim 6, characterized in that: In steps S1 and S2, a wire bar coater is used for coating, and the thickness of each coating layer is 5 to 15 μm.

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