Bone conduction type transcraniocerebral pressure monitoring device and monitoring module

Abstract

The utility model provides a bone conduction type transcraniocerebral pressure monitoring device and a monitoring module. The bone conduction type transcraniocerebral pressure monitoring device comprises a holding device and the monitoring module. The monitoring module includes one or more acceleration sensors, an output device communicatively connected to the acceleration sensors, and a power supply device capable of supplying power to the one or more acceleration sensors and the output device. The one or more acceleration sensors are used for contacting the skin outside the skull so as to sense the craniocerebral pressure acceleration wave of the user for the output device to output.

Description

Technical Field

[0001] The present application relates to a transcranial intracranial pressure monitoring device and a transcranial intracranial pressure monitoring module, and in particular to a bone conduction transcranial intracranial pressure monitoring device and a bone conduction transcranial intracranial pressure monitoring module. Background Art

[0002] The human head is composed of a skull that covers brain tissue, blood and cerebrospinal fluid. Under normal conditions, the internal volume of the cranial cavity remains stable and balanced, and the volume of the cavity produces a uniformly distributed positive pressure, namely intracranial pressure (ICP). Intracranial pressure is used to assess the health of the damaged brain. This technology is often used in intensive care units, especially for patients with head trauma, stroke, brain tumors and after neurosurgery.

[0003] Traditional invasive intracranial pressure (ICP) monitors are the mainstream and most accurate sensing method. The installation of an invasive intracranial pressure monitor is to open a hole in the patient's skull, insert the monitor's catheter into the brain, and connect it to an external monitoring device to track and record changes in intracranial pressure in real time. However, in addition to the high cost and danger of invasive surgery itself, common complications of using invasive intracranial pressure monitors include infection, bleeding, blockage, malfunction, incorrect position, etc. In addition, there are problems such as the increased chance of infection if the intraventricular catheter is placed for more than a week, and it cannot be used for a long time.

[0004] Examples of existing non-invasive intracranial pressure monitoring devices include tympanic pressure sensing, magnetic induction, optical conduction, and mechanical displacement wave. Non-invasive intracranial pressure monitoring devices can effectively solve the problems caused by the above-mentioned invasive surgeries. However, compared to invasive intracranial pressure monitors, non-invasive intracranial pressure monitors have a more indirect sensing method. Some require multiple signal processing such as synthesis, filtering, amplification, and conversion. The final output signal is easily distorted, and the pathological characteristics are not obvious, so it has limited use in diagnosis. In addition, the need to set up a separate signal processor will also make it impossible to miniaturize the overall device and reduce costs, and there is still a lot of room for improvement. Utility Model Content

[0005] The technical problem to be solved by the present application is to provide a bone conduction transcranial intracranial pressure monitoring device and a bone conduction transcranial intracranial pressure monitoring module which are low-cost, miniaturized, simple in structure, have clear and easy-to-read signals and can continuously monitor physiological data related to brain pulsation (The Pulsating Brain) in response to the shortcomings of the existing technology.

[0006] In order to solve the above technical problems, one of the technical solutions adopted by the present application is to provide a bone conduction transcranial pressure monitoring device, which includes: a holding device; an acceleration sensor, which is arranged on the holding device in a manner of being exposed on the surface of the holding device, and is used to contact the skin outside the skull of a user to sense the transcranial pressure acceleration wave of the user to form a first monitoring signal; an output device, which is arranged on the holding device and is communicatively connected to the acceleration sensor, and is used to output the first monitoring signal; and a power supply device, which is arranged on the holding device and is electrically connected to the acceleration sensor and the output device to supply power to the acceleration sensor and the output device. When the user wears the bone conduction transcranial pressure monitoring device, the holding device can fit the acceleration sensor to the skin outside the skull of the user in a manner of contacting the skin outside the skull of the user.

[0007] In order to solve the above-mentioned technical problems, another technical solution adopted in the present application is to provide a bone conduction transcranial pressure monitoring module, which includes: an acceleration sensor, which is used to contact the skin outside the skull to sense the user's transcranial pressure acceleration wave to form a first monitoring signal; an output device, which is communicatively connected to the acceleration sensor, and is used to output the first monitoring signal; and a power supply device, which is electrically connected to the acceleration sensor and the output device to supply power to the acceleration sensor and the output device.

[0008] The bone conduction transcranial pressure monitoring device and bone conduction transcranial pressure monitoring module provided by the present application can provide a new option for non-invasive intracranial pressure-related physiological data monitoring through the technical solution of "an acceleration sensor, which is used to contact the skin outside the skull to sense the user's transcranial pressure acceleration wave to form a first monitoring signal". It can not only provide a low-cost, miniaturized wearable sensing device, but also provide highly accurate TCCP waveforms under non-invasive conditions. The biggest feature of the TCCP waveform is that its output amplitude is large (in volts), which makes the details of the waveform more vivid and easy to identify. Compared with other traditional non-invasive intracranial pressure waveforms, the TCCP waveform is visually clearer, thereby greatly improving the ability to identify various intracranial pressure-related physiological conditions, not only making the diagnosis process more intuitive, but also greatly improving the accuracy of identifying abnormal intracranial pressure conditions. Therefore, both subtle pressure changes and important physiological signals can be captured and analyzed more accurately.

[0009] The details of other effects and embodiments of the present application are described below with reference to the drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0011] Figure 1 is a functional block diagram of a bone conduction transcranial intracranial pressure monitoring module according to an embodiment of the present application;

[0012] Figure 2 2 is a schematic diagram illustrating the use of the bone conduction transcranial intracranial pressure monitoring device according to the first embodiment of the present application;

[0013] Figure 3A It is a three-dimensional schematic diagram of the appearance of the main body (hollow shell) of the bone conduction transcranial pressure monitoring device of the first embodiment of the present application;

[0014] Figure 3B It is a three-dimensional schematic diagram of the appearance of the main body (hollow shell) of the bone conduction transcranial pressure monitoring device of the first embodiment of the present application;

[0015] Figure 4 It is a schematic cross-sectional view of the main body (hollow shell) of the bone conduction transcranial pressure monitoring device according to the first embodiment of the present application;

[0016] Figure 5 is a partially enlarged cross-sectional schematic diagram of a bone conduction transcranial intracranial pressure monitoring device according to the first embodiment of the present application;

[0017] Figure 6 It is a flow chart of the bone conduction transcranial pressure monitoring method of the first embodiment of the present application;

[0018] Figure 7 is a schematic diagram for illustrating an example of a first monitoring signal of the present application;

[0019] Fig. 8A is a schematic diagram for illustrating an example of a first monitoring signal of the present application;

[0020] Figure 8B is a schematic diagram for illustrating an example of a first monitoring signal of the present application;

[0021] Fig. 9 It is a schematic diagram used to display the waveform of transcranial pressure on the left and right sides of the brain when monitoring the user simultaneously;

[0022] Fig.10 is a functional block diagram of a bone conduction transcranial intracranial pressure monitoring device according to a second embodiment of the present application;

[0023] Fig.11 is a schematic diagram for illustrating an example of the second monitoring signal of the present application;

[0024] Fig.12 This is a flow chart of the bone conduction transcranial pressure monitoring method according to the second embodiment of the present application. DETAILED DESCRIPTION

[0025] The following is an explanation of the implementation methods of the "bone conduction transcranial intracranial pressure monitoring device and monitoring module" disclosed in this application through specific embodiments. Those skilled in the art can understand the advantages and effects of this application from the contents disclosed in this specification. This application can be implemented or applied through other different specific embodiments, and the details in this specification can also be modified and changed based on different viewpoints and applications without departing from the concept of this application. In addition, the drawings of this application are only simple schematic illustrations and are not depicted according to actual dimensions. It is stated in advance. The following implementation methods will further explain the relevant technical contents of this application in detail, but the disclosed contents are not intended to limit the scope of protection of this application.

[0026] It should be understood that, although the terms "first", "second", "third", etc. may be used herein to describe various components or signals, these components or signals should not be limited by these terms. These terms are mainly used to distinguish one component from another component, or one signal from another signal. In addition, the term "or" used herein may include any one or more combinations of the associated listed items depending on the actual situation.

[0027] [First Implementation Form]

[0028] See also Figure 1 to Figure 5 , Figure 1 It is a block diagram of a bone conduction transcranial pressure monitoring module 10 according to the first embodiment of the present application. Figure 2 Schematic diagram illustrating the use of the bone conduction transcranial pressure monitoring device 100 according to the first embodiment of the present application. Figure 3A and Figure 3B 1 is a schematic three-dimensional diagram of the appearance of the main body 12 of the bone conduction transcranial intracranial pressure monitoring device 100 according to the first embodiment of the present application. Figure 4 Schematic diagram of the appearance of the main body 12 of the bone conduction transcranial intracranial pressure monitoring device 100 according to the first embodiment of the present application. Figure 5 It is a partially enlarged cross-sectional schematic diagram of the bone conduction transcranial intracranial pressure monitoring device 100 according to the first embodiment of the present application.

[0029] like Figure 1 As shown, the bone conduction transcranial intracranial pressure monitoring module 10 of the first embodiment of the present application includes one or more acceleration sensors 2, an output device 3, and a power supply device 4.

[0030] The acceleration sensor 2 is used to sense the user's transcranial pressure acceleration wave (first monitoring signal L1) by contacting the skin outside the user's skull through bone conduction.

[0031] The acceleration sensor 2 is attached to the skin outside the skull of the user (the person to be tested) to continuously sense the transcranial pressure acceleration wave to form a transcranial pressure (TCCP). Transcranial pressure (TCCP) is a LoG (Laplacian of Gaussian) waveform of the traditional ICP waveform. It is a novel brain dynamics assessment method, which will be described in detail later.

[0032] The output device 3 is used to output the sensing result of the acceleration sensor 2 for access or identification by a reader.

[0033] In this embodiment, the output device 3 is a wireless transmission module, which can transmit the sensing result of the acceleration sensor 2 to other receivable devices by wireless means. For example, the first monitoring signal or other monitoring signals which are the sensing results can be transmitted to a printer, a computer, a tablet computer, a mobile phone, a medical display, etc. For example, the output device 3 can transmit the sensing result of the acceleration sensor 2 to the reader's mobile phone, computer, or a display screen with a wireless receiving function, a speaker with a wireless receiving function, etc., for the reader to use. The wireless transmission module can adopt any structure and transmission method that can achieve the above purpose, such as through Bluetooth, ZigBee, Wi-Fi or any other remote communication method. Since the implementation method of the wireless transmission module is not the focus of this case, it will not be elaborated here. In addition, the output device 3 can also be a wired transmission module, or a display or speaker set on the retaining device 1, etc.

[0034] The power supply device 4 can be any existing power supply device such as a wired power supply, a wireless power supply, a battery, etc. Since the implementation method of the power supply device is not the focus of this case, it will not be described in detail here.

[0035] refer to Figure 3A , 3B , Figure 4 and Figure 5 The bone conduction transcranial pressure monitoring device 100 of the first embodiment of the present application includes a holding device 1, one or more acceleration sensors 2, an output device 3, and a power supply device 4. In other words, the bone conduction transcranial pressure monitoring device 100 includes a bone conduction transcranial pressure monitoring module 10 and a holding device 1. The bone conduction transcranial pressure monitoring device 100 can be fixed to the head of the user U, and the acceleration sensor 2 is in contact with the skin outside the skull of the user U to monitor the user's transcranial pressure-related physiological data in a non-invasive manner. Among them, one or more acceleration sensors 2, the output device 3 and the power supply device 4 are arranged on the holding device 1.

[0036] refer to Figure 2 The holding device 1 is used to place the acceleration sensor 2 on the user's head in a manner that the acceleration sensor 2 fits and contacts the skin outside the user's skull.

[0037] In this embodiment, the retaining device 1 includes a headband 11 and a body 12. The headband 11 is used to fix the body 12 to the head of the user U, and can be an inelastic strap, an adjustable strap, or an elastic strap, etc., which is not limited in this application. Although the headband 11 is used to fix the body 12 to the head of the user U in this embodiment, the application is not limited to this. For example, in other embodiments not shown, the body 12 can also be fixed to the head of the user U by using a head cover, an ear hook, an adhesive, or even manual pressure.

[0038] In this embodiment, the headband 11 has the function of fixing the body 12 to the user's head and also has the function of applying a bias pressure to the body 12 toward the user's head, which can be used as a biasing device. The biasing device can make the acceleration sensor 2 installed on the body 12 closer to the user's skull to enhance the strength and clarity of the bone conduction signal. However, the biasing device is not limited to the implementation form of the headband 11, for example, it can be a shrinkable adhesive, etc., as long as it can apply a bias pressure to the body 12 (acceleration sensor 2) toward the user's head.

[0039] refer to Figure 3A-3B In this embodiment, the body 12 is a hollow shell and has a through hole 14. The through hole 14 allows the acceleration sensor 2 to be disposed in the body 12 and exposed on the surface of the body 12. However, the present application is not limited thereto. For example, in other embodiments not shown, the body 12 may be a substrate or a patch, and the acceleration sensor 2 may be disposed to be completely flush with or even protrude from the surface of the body 12, as long as the acceleration sensor 2, the output device 3 and the power supply device 4 can be carried and the acceleration sensor 2 is exposed on the surface of the body 12.

[0040] In order to continuously monitor the user's transcranial pressure acceleration wave, the acceleration sensor 2 can be set on the user's head through the holding device 1 in a manner of fitting and contacting the skin outside the user's skull.

[0041] The output device 3 is disposed on the holding device 1 and is communicatively connected to the acceleration sensor 2. The power supply device 4 is disposed on the holding device 1 and is connected to the acceleration sensor 2 and the output device 3 for supplying power.

[0042] It should be emphasized that the core part of the present application is the bone conduction transcranial intracranial pressure monitoring module 10 including the acceleration sensor 2, the output device 3 and the power supply device 4. In other words, the implementation method of the holding device 1 is not the technical core of the present case. As long as the acceleration sensor 2 can be in contact with the skin outside the skull of the user U and the output device 3 outputs the first monitoring signal L1, the unique technical effect of the present case can be achieved.

[0043] The acceleration sensor 2 can be a capacitive acceleration sensor, a piezoelectric acceleration sensor, a piezoresistive acceleration sensor, an optical acceleration sensor, and a MEMS (micro-electromechanical system) acceleration sensor. The capacitive acceleration sensor has high sensitivity and low power consumption, and is suitable for applications that require long-term stability. The piezoelectric acceleration sensor has a wide dynamic range and high-frequency response, and is often used in high-vibration environments. The piezoresistive acceleration sensor has a simple structure and low manufacturing cost, but may be affected by temperature changes. The optical acceleration sensor provides the advantages of higher accuracy and less susceptibility to interference, but the cost is higher. MEMS acceleration sensors are widely used in consumer electronic products because of their miniaturization, low power consumption and low cost. The acceleration sensor 2 senses physiological data related to transcranial brain pressure through bone conduction, so a capacitive acceleration sensor or a MEMS acceleration sensor is preferred.

[0044] In detail, the advantages of capacitive acceleration sensors are high sensitivity and stability. When they are set in wearable devices to measure acceleration waves transmitted through solids such as bone conduction, capacitive sensors can accurately detect tiny acceleration changes. In addition, capacitive acceleration sensors usually have good long-term stability, which is very important for wearable devices that are worn for a long time, and their low energy consumption characteristics help to extend the battery life of the device.

[0045] On the other hand, MEMS accelerometers have the advantages of miniaturization, low cost and low power consumption in wearable devices. The small size of MEMS accelerometers is very suitable for wearable devices with limited volume, and the cost-effectiveness in production makes them an ideal choice for mass production. The low power consumption characteristics ensure the feasibility of long-term operation, and they are also easy to integrate with other electronic components, enabling wearable devices to achieve multifunctionality.

[0046] refer to Figure 6 , the bone conduction transcranial pressure monitoring method of this embodiment implemented by using the bone conduction transcranial pressure monitoring device 100 or the bone conduction transcranial pressure monitoring module 10 of this embodiment is explained.

[0047] Step S601, the acceleration sensor 2 (in this embodiment, the through hole 14 of the body 12) in the bone conduction transcranial intracranial pressure monitoring device 100 or the bone conduction transcranial intracranial pressure monitoring module 10 is brought into contact with and attached to the skin outside the skull of the user U;

[0048] Step S602, obtaining the transcranial cerebral pressure acceleration wave (transcranial cerebral pressure TCCP) of the monitored person (user U) through the acceleration sensor 2 as the first monitoring signal L1;

[0049] Step S603, setting the output device 3 to output the first monitoring signal L1.

[0050] According to the above-mentioned bone conduction transcranial pressure monitoring method, the transcranial pressure TCCP for monitoring the user U can be obtained.

[0051] Below, reference Figure 7 , 8A and 8B, the application of the transcranial pressure TCCP (first monitoring signal L1) obtained by the bone conduction transcranial pressure monitoring method of this embodiment in transcranial pressure related physiological phenomena is explained.

[0052] Transcranial pressure (TCCP) is a novel method for assessing brain dynamics. Figure 7 As shown in the schematic diagram of , the transcranial cerebral pressure TCCP is a continuous waveform, and each cycle includes six inflection points, namely the first inflection point 710a, the second inflection point 720a, the third inflection point 730a, the fourth inflection point 740a, the fifth inflection point 750a and the sixth inflection point 760a. In the transcranial cerebral pressure (TCCP) measurement, the observed continuous waveform shows an amplitude of the order of volt (V). This feature is different from the signal of the order of microvolt (μV) or millivolt (mV), which clearly shows that the intensity of the transcranial cerebral pressure TCCP signal is at a higher voltage level. By observing the changes in each inflection point in each cycle of the transcranial cerebral pressure TCCP, the reader can more easily observe the transcranial cerebral pressure-related physiological data of the monitored person (user U), and more accurately determine the pathological problems that may occur in the monitored person. It should be noted that the reader here refers to a person who has experience or relevant knowledge in brain pressure waveform and diagnosis, and can make pathological judgments based on the transcranial cerebral pressure-related physiological data.

[0053] As mentioned above, TCCP can be used to monitor subtle changes in brain pressure and thus reflect possible abnormalities in intracranial pressure. In detail, according to the Monro-Kellie Doctrine, changes in the total volume of intracranial fluid are accompanied by changes in intracranial pressure (ICP). Cerebral perfusion pressure is calculated by subtracting intracranial pressure from mean arterial pressure, using the formula CPP = MAP – ICP. The relative constancy of ICP is essential for maintaining cerebral perfusion pressure (CPP), which in turn determines the overall cerebral blood flow (CBF). If the volume of a component within the skull increases, the volume of a different component must decrease to maintain this balance and maintain normal ICP. Cerebral perfusion pressure (CPP), that is, the pressure of blood flow to the brain, is usually quite constant due to autoregulation, but for abnormal mean arterial pressure (MAP) or abnormal ICP, one of the main dangers of increased ICP is that the body's autoregulatory mechanism will reduce CPP and thus reduce overall cerebral blood flow and cause ischemia. In other words, if ICP is close to the MAP level due to abnormality, cerebral perfusion will decrease. The body responds to a drop in CPP by increasing systemic blood pressure and dilating cerebral blood vessels. This will cause cerebral blood volume to increase again, which in turn increases ICP, further reducing CPP, creating a vicious cycle. This leads to widespread reductions in cerebral flow and perfusion, ultimately leading to ischemia and cerebral infarction. Such abnormal increases and decreases in CPP can be reflected in the real-time pressure pulsation of the brain, which is transcranial pressure TCCP. Transcranial pressure TCCP can be used to assess the health of a damaged brain by continuously monitoring the cerebral pulse pressure formed by pressure fluctuations in the brain. The core of transcranial pressure wave monitoring is to measure and analyze changes in cerebrospinal fluid pressure, which helps identify potentially dangerous conditions such as cerebral edema, cerebral hemorrhage, or intracranial hypertension.

[0054] Regarding the actual industrial application of the transcranial pressure TCCP formed in this embodiment, Fig. 8A , 8B To illustrate, let's use TCCP to identify various possible pathological problems.

[0055] like Fig. 8A In the example, the monitored person is a young male who has a history of taking anti-anxiety drugs. He reported that he felt a momentary emotion of panic during the monitoring process. During the monitoring process, at the time point corresponding to the momentary emotion of panic, it can be observed that the transcranial cerebral pressure TCCP showed a significant decrease in the second turning point 702a of the cycle.

[0056] like Figure 8B In the example, the monitored person suffered from sleep disorders for a long time and had no history of heart disease. He was diagnosed with right carotid artery stenosis. Obvious pressure turbulence could be observed in the waveform of his transcranial cerebral pressure (TCCP) (multiple red circles).

[0057] From the above examples, it can be seen that TCCP monitoring technology can be effectively used to identify and evaluate various brain conditions and related pathological problems. Fig. 8A In the example shown, when a young male subject was experiencing panic, the TCCP waveform clearly reflected the changes in this psychological state, demonstrating the potential of this technology in sensing and recording physiological reactions caused by emotions. Figure 8B In the case of a patient who had long suffered from sleep disorders and was diagnosed with carotid artery stenosis, the TCCP waveform showed obvious pressure turbulence, which further proved the effectiveness of this technology in monitoring more complex brain pathological conditions. It can be seen that transcranial pressure TCCP monitoring technology can not only provide in-depth insights into the physiological state related to intracranial pressure, but also become an important tool for diagnosing and monitoring brain health.

[0058] also, Fig. 9 Displays the data application method of simultaneously monitoring the transcranial pressure TCCP of the left and right brain sides of the user U. Fig. 9 In the embodiment not shown in the figure, the number of acceleration sensors 2 can be at least two, and they are arranged on the holding device 1 in a manner of being spaced a predetermined distance from each other. When the user U wears the holding device 1, at least one of the at least two acceleration sensors 2 can contact and fit the skin on the left side of the skull of the user, and at least another of the at least two acceleration sensors 2 can contact and fit the skin on the right side of the skull of the user U, so that the transcranial pressure TCCP of the left and right sides of the brain of the user U can be monitored simultaneously.

[0059] Fig. 9 The waveforms of the left brain monitoring signal Left TCCP and the right brain monitoring signal Right TCCP obtained by the two acceleration sensors 2 can be seen in FIG. Fig. 9 In the figure, the monitored person is a young woman with symptoms of left venous stenosis. It can be clearly seen that the pathological state of transcranial pressure TCCP corresponding to the symptoms of left venous stenosis provides real-time changes in brain pressure physiological data. The waveform vibration represents the abnormal part (the dotted ellipse box). It can be seen that since the right brain perfusion pressure drops more than the left brain, it means that the transcranial pressure of the right brain is higher than the perfusion pressure of the left brain, resulting in insufficient autonomic regulation.

[0060] Compared with the left brain monitoring signal Left TCCP and the right brain monitoring signal Right TCCP, the abnormality can be clearly identified just by comparing the left and right waveforms. Fig. 9 The waveforms sensed by other non-invasive testing equipment, such as TCD (intracranial sound wave) and ABP (finger blood pressure monitor), cannot clearly show the difference between the left and right brain waveforms.

[0061] From the above, it can be seen that transcranial pressure-related physiological data such as transcranial pressure TCCP can provide the reader (diagnostician) with more and clearer applicable information related to the pathology of the monitored person (user U).

[0062] The advantages of using TCCP to monitor physiological data related to transcranial pressure include the following:

[0063] Advantage 1: No invasive catheter placement is required for evaluation: The measurement of transcranial intracranial pressure (TCCP) is non-invasive. It only requires the acceleration sensor 2 to be attached to the skull (skin outside the skull), such as the frontal bone, and the LoG-type intracranial pressure waveform (transcranial intracranial pressure waveform) can be obtained based on the principle of bone conduction.

[0064] Advantage 2: Excellent signal-to-noise ratio: TCCP has a good signal-to-noise ratio, which means that TCCP can provide clearer and more accurate brain dynamics and better resist interference and noise. This is crucial for accurately assessing the circulatory state and stably monitoring the dynamic changes of brain blood flow and pressure.

[0065] Advantage 3: High-frequency response capability: The technical design of transcranial pressure (TCCP) enables it to capture the high-frequency components of brain pressure, which are very important for evaluating the rapid dynamic changes of brain blood.

[0066] Advantage 4: The device is miniaturized and can be based on low-power Bluetooth transmission, which can achieve 7 / 24 (seven days a week, 24 hours a day) continuous intracranial pressure monitoring.

[0067] That is, in this embodiment, as long as the acceleration sensor 2 is worn on the skin outside the skull, it can provide real-time intracranial hemodynamic parameters through bone conduction for pathological interpretation or reference, and non-invasive real-time transcranial intracranial pressure monitoring also helps to identify and quantify abnormal changes. In addition, since the acceleration sensor 2 does not need to add other complex filtering, amplification signal conversion and other processors, the whole can be miniaturized, and the portability and simple operation are combined for telemedicine applications, which can promote the popularization of monitoring systems even in outlying islands and remote areas. Confirming TCCP as a non-invasive cerebral blood flow monitoring tool is intended to enhance medical care and improve treatment effects.

[0068] [Second Implementation Form]

[0069] refer to Fig.10 The second embodiment of the present invention is a bone conduction transcranial pressure monitoring module 10A. The second embodiment of the present invention is substantially the same as the previous embodiment except for the addition of a processor 5 (integrator), and the similarities are not further described.

[0070] In this embodiment, the processor 5 is disposed on the holding device 1 and is communicatively connected to the acceleration sensor 2 and the output device 3. The power supply device 4 is configured to supply power to the acceleration sensor 2, the output device 3 and the processor 5. The processor 5 is configured to integrate the first monitoring signal L1 output by the acceleration sensor 2 twice to form a second monitoring signal L2. The output device 3 outputs the second monitoring signal L2.

[0071] like Fig.11 As shown, the second monitoring signal L2 is the perfusion pressure waveform of the transcranial brain pressure. The waveform is similar to the individual ICP waveform related to the heartbeat, which has three judgment values ​​of P1, P2 and P3, and can provide the reader who needs to observe the pressure waveform for interpretation. The individual ICP waveform related to the heartbeat is a graph that reflects the changes in brain pressure during the heartbeat, with three main peaks of P1, P2 and P3, each of which represents a different physiological phenomenon. P1 (Percussion Wave) is the first peak in the waveform and is usually the highest. P1 represents the effect of arterial blood flow on brain tissue and cerebrospinal fluid (CSF), reflecting the real-time pressure effect of cardiac output on cerebral blood vessels. P2 (Rebound Wave): P2 is the second peak in the waveform. The height may vary compared with P1, depending on the elasticity of the brain tissue and the state of cerebrospinal fluid dynamics, and is usually related to the flexibility of the brain parenchyma and the response of the brain tissue to the initial increase in blood flow. P3 (Dicrotic Wave) is the third peak in the waveform, which is usually the lowest. This peak is related to the mitral valve rebound of arterial blood pressure. P3 is associated with the second half of the cardiac cycle and reflects the hemodynamics of the late cardiac cycle. These peaks are used to assess the state of intracerebral pressure because they provide information about cerebral hemodynamics, the elasticity of brain tissue, and the state of cerebrospinal fluid pressure.

[0072] Invasive methods provide the most direct and accurate measurement for obtaining ICP waveforms, but they carry higher risks, including the risk of infection and bleeding. Non-invasive methods have lower risks, but usually provide indirect or speculative measurement results. The waveforms measured in the prior art are difficult to achieve the amplitude of the original measurement signal, which is in the order of volts (V). Since subsequent signal processing such as amplification and filtering cannot be omitted, it is easy to cause serious distortion of the signal during interpretation. In comparison, the ICP waveform monitoring method provided in this embodiment can obtain a similar ICP waveform with less computing cost and a larger amplitude, providing a new option for obtaining an ICP waveform.

[0073] It should be noted that in this embodiment, the output device 3 is used to output the second monitoring signal L2. However, in accordance with the needs of the reader, the output device 3 can also output the first monitoring signal L1, or the first monitoring signal L1 and the second monitoring signal L2.

[0074] In addition, the bone conduction transcranial pressure monitoring device 100 in the first embodiment is added with a processor 5 to become a bone conduction transcranial pressure monitoring device 100A. The bone conduction transcranial pressure monitoring device 100A can be installed on the head of the user U, and continuously output the second monitoring signal L2, so that the reader can continuously monitor the user U's transcranial pressure-related physiological data.

[0075] Fig.12 The following describes a second embodiment of a bone conduction transcranial pressure monitoring method implemented by the bone conduction transcranial pressure monitoring device 100A or the bone conduction transcranial pressure monitoring module 10A of this embodiment.

[0076] Step S1201, the acceleration sensor 2 (in this embodiment, the through hole 14 of the body 12) in the bone conduction transcranial intracranial pressure monitoring device 100 is brought into contact with and attached to the skin outside the skull of the monitored person (user U);

[0077] Step S1202, obtaining a transcranial cerebral pressure acceleration wave (transcranial cerebral pressure TCCP) through the acceleration sensor 2 as a first monitoring signal L1;

[0078] Step S1203, integrating the first monitoring signal L1 obtained in the previous step S1102 twice to obtain a second monitoring signal L2 by the processor 5; and

[0079] Step S1204, setting the output device 3 to output the second monitoring signal L2.

[0080] According to the above-mentioned bone conduction transcranial intracranial pressure monitoring method, a perfusion pressure waveform for monitoring the transcranial intracranial pressure of the user U can be obtained, that is, an individual ICP waveform related to the heartbeat.

[0081] [Beneficial Effects of Embodiments]

[0082] In summary, the acceleration sensor 2 used in the bone conduction transcranial pressure monitoring device 100 proposed in the present application can monitor the user's transcranial pressure-related physiological data in a non-invasive manner. In other words, the bone conduction transcranial pressure monitoring device and bone conduction transcranial pressure monitoring module provided by the present application can provide users with a new option for non-invasive monitoring of intracranial pressure-related physiological data. In addition, the bone conduction transcranial pressure monitoring device provided by the present application is a low-cost miniature wearable sensing device that can provide the user with a waveform of intracranial pressure-related physiological data (TCCP waveform) in a non-invasive manner, and the waveform is clearer and easier to read than other existing non-invasive intracranial pressure-related physiological data monitoring waveforms, and can clearly reflect various intracranial pressure-related physiological conditions.

[0083] The embodiments and / or implementation methods described above are only used to illustrate the preferred embodiments and / or implementation methods for realizing the technology of the present application, and are not intended to limit the implementation methods of the technology of the present application in any form. Any technical personnel in this field may make slight changes or modifications to other equivalent embodiments without departing from the scope of the technical means disclosed in the content of the present application, but they should still be regarded as technologies or embodiments that are essentially the same as the present application.

Claims

1. A bone conduction transcranial pressure monitoring device, characterized in that: The bone conduction transcranial pressure monitoring device comprises: a retaining device; One or more acceleration sensors are disposed on the holding device in a manner of being exposed on the surface of the holding device, and are used to contact the skin outside the skull of a user to sense the transcranial pressure acceleration wave of the user to form a first monitoring signal; an output device, disposed on the holding device and communicatively connected to the acceleration sensor, for outputting the first monitoring signal; and a power supply device, which is disposed on the holding device and is electrically connected to the acceleration sensor and the output device to supply power to the acceleration sensor and the output device; When the user wears the bone conduction transcranial pressure monitoring device, the retaining device can fit the acceleration sensor to the skin outside the user's skull in a manner that the sensor contacts the skin outside the user's skull.

2. The bone conduction transcranial pressure monitoring device according to claim 1, characterized in that: The holding device further comprises a hollow shell, and the acceleration sensor, the output device and the power supply device are all arranged in the hollow shell.

3. The bone conduction transcranial pressure monitoring device according to claim 1, characterized in that: The holding device further comprises a biasing device for applying a biasing pressure to the acceleration sensor toward the user when the holding device fits the acceleration sensor to the skin outside the skull of the user.

4. The bone conduction transcranial pressure monitoring device according to claim 1, characterized in that: It further includes a processor, which is arranged in the holding device and can perform secondary integration on the first monitoring signal output by the acceleration sensor to form a second monitoring signal, and the output device outputs the second monitoring signal and / or the first monitoring signal.

5. The bone conduction transcranial pressure monitoring device according to claim 1, characterized in that: The output device includes a wired and / or wireless transmission module for transmitting the first monitoring signal.

6. The bone conduction transcranial pressure monitoring device according to claim 1, characterized in that: The output device is a display and / or a speaker.

7. The bone conduction transcranial pressure monitoring device according to claim 1, characterized in that: There are at least two acceleration sensors, which are arranged on the retaining device at a predetermined distance, so that when the user wears the bone conduction transcranial pressure monitoring device, the acceleration sensors can simultaneously contact and adhere to the outer skin of the left skull and the outer skin of the right skull of the user.

8. The bone conduction transcranial pressure monitoring device according to any one of claims 1 to 7, characterized in that: The acceleration sensor is a capacitive acceleration sensor, a piezoelectric acceleration sensor, or a piezoresistive acceleration sensor.

9. A bone conduction transcranial pressure monitoring module, characterized in that: The bone conduction transcranial pressure monitoring module comprises: One or more acceleration sensors are used to contact the skin outside the skull to sense the user's transcranial pressure acceleration wave to form a first monitoring signal; an output device, communicatively connected to the acceleration sensor, for outputting the first monitoring signal; and A power supply device is electrically connected to the acceleration sensor and the output device to supply power to the acceleration sensor and the output device.

10. The bone conduction transcranial pressure monitoring module according to claim 9, characterized in that: It further includes a processor that can perform secondary integration on the first monitoring signal output by the acceleration sensor to form a second monitoring signal, and the output device outputs the second monitoring signal and / or the first monitoring signal.

Images