Serum extraction pretreatment device

By designing an automated serum extraction pretreatment device, the problem of inefficiency of traditional serum extraction methods is solved, efficient and safe blood sample processing is achieved, and high throughput requirements of modern laboratories are adapted to the high throughput requirements.

CN222196000UActive Publication Date: 2024-12-20ZHANGYE HOPE FARMING & ANIMAL HUSBANDRY IND SCI & TECH CO LTD
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Patent Information

Application Number
CN202420747238.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-11
Publication Date
2024-12-20
Estimated Expiration
2034-04-11

AI Technical Summary

Technical Problem

Traditional serum extraction methods are inefficient, manual centrifugation, separation and transfer processes are time-consuming and error-prone, and cannot meet the needs of modern laboratories for high-throughput sample processing.

Method used

A serum extraction pretreatment device was designed, using an automated centrifugal and separation system, including the equipment body, control panel, centrifugal disk, arc groove, insulation layer, clamping block and motor, through automatic centrifugal and insulation layer Ensure the sample temperature is stable, the clamping block prevents the test tube from falling off when rotating at high speed, and improves processing speed and safety.

Benefits of technology

It significantly improves the efficiency of blood sample processing, reduces manual operation time, improves the safety of serum processing process and the stability of sample temperature, and adapts to the needs of modern laboratories for high-throughput sample processing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of serum extraction, and discloses a serum extraction pretreatment device which comprises an equipment main body, a control panel, a centrifugal disc, an arc-shaped groove, a heat preservation layer, a placement table, a test tube groove, a first clamping block, a second clamping block, a movable rod, a connecting piece, a supporting arm, a connecting rod, a bearing and a safety cover, a control panel is arranged at the left end of the equipment body, a heat preservation layer is arranged in a centrifugal disc, a second clamping block is arranged on the front side of a first clamping block, and the two clamping blocks are used for firmly clamping a test tube and preventing the test tube from moving or falling off during high-speed rotation. According to the serum extraction pretreatment device, the blood sample treatment efficiency is greatly improved through an automatic sample treatment system, a safety cover is automatically closed, rapid centrifugation is carried out, the time needed by manual operation is shortened through automation of the series of processes, and more samples can be treated within a short time.
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Description

Technical Field

[0001] The utility model relates to the technical field of serum extraction, in particular to a serum extraction pretreatment device. Background Art

[0002] The serum extraction pretreatment device is designed to improve the efficiency and accuracy of extracting serum from blood samples. In clinical diagnosis, drug testing and biomedical research, serum is an extremely important biological sample because it contains rich biomarkers such as proteins, hormones and antibodies, which play a key role in disease diagnosis and biological research.

[0003] Traditional serum extraction methods usually include manual centrifugation, separation and transfer processes, which are not only time-consuming and error-prone, but also inefficient when processing a large number of samples. With the deepening of medical research and the increasing demand for high-throughput sample processing in clinical laboratories, this traditional method is gradually unable to meet the needs of modern laboratories. In order to solve these problems, the development of serum extraction pretreatment devices has become an important research direction. These devices significantly improve the processing speed and accuracy of sample processing through automated centrifugation and separation processes. Utility Model Content

[0004] 1. Technical issues to be resolved

[0005] The utility model aims to provide a serum extraction pretreatment device to solve the problem of low efficiency of the traditional serum extraction method proposed in the above background technology.

[0006] (II) Technical solution

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a serum extraction pretreatment device, which includes an equipment body, a control panel, a centrifugal disk, an arc-shaped groove, a heat preservation layer, a placement table, a test tube slot, a first clamping block, a second clamping block, a movable rod, a telescopic spring, a spring seat, a rotor, a driven gear, a driving gear, a motor, a telescopic motor, a transmission rod, a support rod, a connecting piece, a support arm, a connecting rod, a bearing and a safety cover. A control panel is arranged at the left end of the equipment body, a centrifugal disk is arranged at the upper end of the equipment body, an arc-shaped groove is arranged at the upper end of the centrifugal disk, a heat preservation layer is arranged inside the centrifugal disk, a placement table is arranged in the middle of the arc-shaped groove, a plurality of test tube slots are arranged inside the equipment body, a first clamping block is arranged inside the equipment body, a second clamping block is arranged on the front side of the first clamping block, and the two clamping blocks are used to firmly clamp the test tube to prevent it from moving or falling off during high-speed rotation.

[0008] Preferably, movable rods are provided at the front and rear ends of the first clamping block and the second clamping block, and telescopic springs are provided at the outer rings of the movable rods, which work together to provide the necessary tension and elasticity for the clamping blocks to adapt to test tubes of different sizes and maintain their stability.

[0009] Preferably, a spring seat is provided at the other end of the telescopic spring away from the clamping block, and the spring seat is connected to the inside of the device body.

[0010] Preferably, a rotor is disposed at the lower end of the centrifugal disk, and a driven gear is disposed at the lower end of the rotor.

[0011] Preferably, a driving gear is provided at the rear end of the driven gear, and a motor is provided at the rear end of the driving gear. The teeth of the driven gear and the driving gear are engaged with each other to transmit and adjust the power of the motor to the rotor, thereby ensuring the accuracy and consistency of the centrifugal speed.

[0012] Preferably, a telescopic motor is provided at the rear end of the device body, and a transmission rod is provided at the upper end of the telescopic motor.

[0013] Preferably, a support rod is provided at the upper end of the transmission rod, a connecting piece is provided at the upper end of the support rod, and the other end of the connecting piece is connected to the support arm.

[0014] Preferably, a connecting rod is provided at the lower end of the support arm, a bearing is provided on the lower side of the connecting rod, and the bearing is installed inside a safety cover, which is used to close the device during operation to prevent sample leakage or splashing when the test tube ruptures.

[0015] Compared with the prior art, the beneficial effects of the utility model are:

[0016] 1. The serum extraction pretreatment device greatly improves the efficiency of blood sample processing through an automated sample processing system, automatically closes the safety cover, and performs rapid centrifugation. The automation of this series of processes reduces the time required for manual operations, making it possible to process more samples in a shorter time;

[0017] 2. The serum extraction pretreatment device has two clamping blocks for firmly clamping the test tube to prevent it from moving or falling off during high-speed rotation, thereby improving the safety of the serum treatment process;

[0018] 3. The heat preservation layer in the serum extraction pretreatment device ensures the stability of the sample temperature during the entire pretreatment process, which is particularly important for maintaining the integrity and activity of biological samples (such as proteins and cytokines in serum). BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0020] Figure 2 This is a schematic diagram of the cross-sectional structure of the centrifugal disc of the utility model;

[0021] Figure 3 This is a schematic diagram of the test tube clamp structure of the utility model;

[0022] Figure 4 This is a schematic diagram of the cross-sectional structure of the utility model equipment;

[0023] Figure 5 This is a schematic diagram of the structure of the telescopic rod module of the utility model;

[0024] Figure 6 This is a schematic diagram of the safety cover structure of the utility model.

[0025] In the figure: 1. Equipment body; 2. Control panel; 3. Centrifugal disc; 4. Arc-shaped groove; 5. Insulation layer; 6. Placement table; 7. Test tube slot; 8. First clamping block; 9. Second clamping block; 10. Movable rod; 11. Telescopic spring; 12. Spring seat; 13. Rotor; 14. Driven gear; 15. Driving gear; 16. Motor; 17. Telescopic motor; 18. Transmission rod; 19. Support rod; 20. Connector; 21. Support arm; 22. Connecting rod; 23. Bearing; 24. Safety cover. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0027] Example 1

[0028] See also Figure 1-Figure 6The utility model provides a technical solution: a serum extraction pretreatment device, which includes an equipment body 1, a control panel 2, a centrifugal disk 3, an arc-shaped groove 4, a heat preservation layer 5, a placement table 6, a test tube slot 7, a first clamping block 8, a second clamping block 9, a movable rod 10, a telescopic spring 11, a spring seat 12, a rotor 13, a driven gear 14, a driving gear 15, a motor 16, a telescopic motor 17, a transmission rod 18, a support rod 19, a connecting piece 20, a support arm 21, a connecting rod 22, a bearing 23 and a safety cover 24. The left end of the equipment body 1 is provided with a control panel 2, the upper end of the equipment body 1 is provided with a centrifugal disk 3, the upper end of the centrifugal disk 3 is provided with an arc-shaped groove 4, and the centrifugal disk 3 is provided with a support arm 21. An insulation layer 5 is arranged inside, a placing table 6 is arranged in the middle of the arc-shaped groove 4, several test tube grooves 7 are arranged inside the equipment body 1, a first clamping block 8 is arranged inside the equipment body 1, a second clamping block 9 is arranged on the front side of the first clamping block 8, movable rods 10 are arranged at the front and rear ends of the first clamping block 8 and the second clamping block 9, and a telescopic spring 11 is arranged on the outer ring of the movable rod 10. The core of the equipment is a centrifugal disk 3 located on the equipment body 1, an arc-shaped groove 4 is installed above the centrifugal disk 3 for placing the test tube groove 7, and the test tube groove 7 is equipped with a first clamping block 8 and a second clamping block 9. These clamping blocks clamp the test tube through the movable rod 10, the telescopic spring 11 and the spring seat 12 to ensure the stability of the test tube during the centrifugation process.

[0029] A spring seat 12 is provided at the other end of the telescopic spring 11 away from the clamping block, and the spring seat 12 is connected to the inside of the equipment body 1. A rotor 13 is provided at the lower end of the centrifugal disc 3, and a driven gear 14 is provided at the lower end of the rotor 13. A driving gear 15 is provided at the rear end of the driven gear 14, and a motor 16 is provided at the rear end of the driving gear 15. The teeth of the driven gear 14 and the driving gear 15 are engaged with each other. The rotor 13 is located below the centrifugal disc 3, and the rotor is driven to rotate by the driven gear 14, the driving gear 15 and the motor 16. The telescopic motor 17 is located above the rotor 13 and is connected to the rotor through a transmission rod 18 and a support rod 19 to help control the speed.

[0030] A telescopic motor 17 is provided at the rear end of the device body 1, a transmission rod 18 is provided at the upper end of the telescopic motor 17, a support rod 19 is provided at the upper end of the transmission rod 18, a connecting piece 20 is provided at the upper end of the support rod 19, the other end of the connecting piece 20 is connected to a support arm 21, a connecting rod 22 is provided at the lower end of the support arm 21, a bearing 23 is provided on the lower side of the connecting rod 22, the bearing 23 is installed inside the safety cover 24, a safety cover 24 is installed above the device body 1, it is connected to the bearing 23 through the connecting rod 22, the bearing 23 allows the safety cover 24 to rotate, and the safety cover 24 covers the centrifugal disk 3 to ensure that the sample is safe and leak-free during the centrifugation process.

[0031] Working principle: The core of the device is the centrifugal disc 3 located on the device body 1. An arc-shaped groove 4 is installed above the centrifugal disc 3 for placing a test tube slot 7. The test tube slot 7 is equipped with a first clamping block 8 and a second clamping block 9. These clamping blocks clamp the test tube through a movable rod 10, a telescopic spring 11 and a spring seat 12 to ensure that the test tube is stable during the centrifugation process. Below the centrifugal disc 3 is a rotor 13, which is driven to rotate by a driven gear 14, a driving gear 15 and a motor 16. The telescopic motor 17 is located above the rotor 13 and is connected to the rotor through a transmission rod 18 and a support rod 19 to assist in controlling the speed. The connecting piece 20 and the support arm 21 are used to stabilize the entire structure. A safety cover 24 is installed on the side, which is connected to the bearing 23 through a connecting rod 22. The bearing 23 allows the safety cover 24 to rotate. The safety cover 24 covers the top of the centrifugal disk 3 to ensure that the sample is safe and leak-free during the centrifugation process. During the operation, the user can set the centrifugation parameters through the control panel 2. Once the operation starts, the motor 16 will drive the rotor 13 to rotate, and the speed is controlled by the cooperation of the driving gear 15 and the driven gear 14. The test tube is placed in the test tube slot 7 and is firmly clamped by the first clamping block 8 and the second clamping block 9. During the high-speed rotation, the serum and other components in the blood sample are separated. During the whole process, the safety cover 24 remains closed to ensure the safety of the operation.

[0032] Example 2

[0033] See also Figure 1-Figure 4 The utility model provides a technical solution: a serum extraction pretreatment device, which includes a device body 1, a control panel 2, a centrifugal disk 3, an arc-shaped groove 4, a heat preservation layer 5, a placement table 6, a test tube slot 7, a first clamping block 8, a second clamping block 9, a movable rod 10, a telescopic spring 11, a spring seat 12, a rotor 13, a driven gear 14, a driving gear 15, a motor 16 and a safety cover 24. The left end of the device body 1 is provided with a control panel 2, the upper end of the device body 1 is provided with a centrifugal disk 3, the upper end of the centrifugal disk 3 is provided with an arc-shaped groove 4, the inside of the centrifugal disk 3 is provided with a heat preservation layer 5, and the middle of the arc-shaped groove 4 is provided with a A placing table 6, several test tube slots 7 are arranged inside the equipment body 1, a first clamping block 8 is arranged inside the equipment body 1, a second clamping block 9 is arranged on the front side of the first clamping block 8, movable rods 10 are arranged at the front and rear ends of the first clamping block 8 and the second clamping block 9, and a telescopic spring 11 is arranged on the outer ring of the movable rod 10. The core of the equipment is a centrifugal disk 3 located on the equipment body 1, and an arc-shaped groove 4 is installed above the centrifugal disk 3 for placing the test tube slot 7. The test tube slot 7 is equipped with a first clamping block 8 and a second clamping block 9. These clamping blocks clamp the test tube through the movable rod 10, the telescopic spring 11 and the spring seat 12 to ensure the stability of the test tube during the centrifugation process.

[0034] A spring seat 12 is provided at the other end of the telescopic spring 11 away from the clamping block, and the spring seat 12 is connected to the inside of the equipment body 1. A rotor 13 is provided at the lower end of the centrifugal disk 3, and a driven gear 14 is provided at the lower end of the rotor 13. A driving gear 15 is provided at the rear end of the driven gear 14, and a motor 16 is provided at the rear end of the driving gear 15. The teeth of the driven gear 14 and the driving gear 15 are engaged with each other. The rotor 13 is located below the centrifugal disk 3, and the rotor is driven to rotate by the driven gear 14, the driving gear 15 and the motor 16. A safety cover 24 is installed above the equipment body 1, and the safety cover 24 covers the top of the centrifugal disk 3 to ensure that the sample is safe and leak-free during the centrifugation process.

[0035] Compared with Example 1, Example 2 lacks components such as the telescopic motor 17, the transmission rod 18, the support rod 19, etc., so that the safety cover 24 has no power support, but the number of electronic parts of the device is reduced, the structure is simpler, and the probability of failure is reduced. Other beneficial effects are consistent with Example 1.

[0036] Finally, it should be noted that the above content is only used to illustrate the technical solution of the utility model, rather than to limit the protection scope of the utility model. Simple modifications or equivalent substitutions of the technical solution of the utility model by ordinary technicians in this field do not deviate from the essence and scope of the technical solution of the utility model.

Claims

1. A serum extraction pretreatment device, comprising a device body (1), a control panel (2) and a centrifugal disk (3), characterized in that: A control panel (2) is arranged at the left end of the device body (1), a centrifugal disc (3) is arranged at the upper end of the device body (1), an arc-shaped groove (4) is arranged at the upper end of the centrifugal disc (3), a heat-insulating layer (5) is arranged inside the centrifugal disc (3), a placing table (6) is arranged in the middle of the arc-shaped groove (4), a plurality of test tube slots (7) are arranged inside the device body (1), a first clamping block (8) is arranged inside the device body (1), and a second clamping block (9) is arranged on the front side of the first clamping block (8).

2. A serum extraction pretreatment device according to claim 1, characterized in that: Movable rods (10) are provided at the front and rear ends of the first clamping block (8) and the second clamping block (9), and the outer ring of the movable rod (10) is provided with a telescopic spring (11).

3. A serum extraction pretreatment device according to claim 2, characterized in that: A spring seat (12) is provided at the other end of the telescopic spring (11) away from the clamping block, and the spring seat (12) is connected to the inside of the device body (1).

4. A serum extraction pretreatment device according to claim 1, characterized in that: A rotor (13) is disposed at the lower end of the centrifugal disc (3), and a driven gear (14) is disposed at the lower end of the rotor (13).

5. A serum extraction pretreatment device according to claim 4, characterized in that: A driving gear (15) is arranged at the rear end of the driven gear (14), and a motor (16) is arranged at the rear end of the driving gear (15). The teeth of the driven gear (14) and the driving gear (15) are engaged with each other.

6. A serum extraction pretreatment device according to claim 5, characterized in that: A telescopic motor (17) is arranged at the rear end of the device body (1), and a transmission rod (18) is arranged at the upper end of the telescopic motor (17).

7. A serum extraction pretreatment device according to claim 6, characterized in that: A support rod (19) is disposed at the upper end of the transmission rod (18), a connecting piece (20) is disposed at the upper end of the support rod (19), and the other end of the connecting piece (20) is connected to a support arm (21).

8. A serum extraction pretreatment device according to claim 7, characterized in that: A connecting rod (22) is provided at the lower end of the support arm (21), a bearing (23) is provided at the lower side of the connecting rod (22), and the bearing (23) is installed inside the safety cover (24).