Novel measuring cylinder for clinical test

By integrating the aeration assembly and half-splicing design in the clinical trial measuring cylinder, the problem of incomplete dissolution of solid drugs is solved, faster dissolution speed and better sealing are achieved, and the accuracy of experimental results is ensured.

CN222196718UActive Publication Date: 2024-12-20BAIKANG (HUBEI) PHARM TECH CO LTD
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Patent Information

Application Number
CN202420016249.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-01-04
Publication Date
2024-12-20
Estimated Expiration
2034-01-04

AI Technical Summary

Technical Problem

In clinical trials, the dissolution rate of solid drugs in liquid is slow, which can easily lead to the precipitation of the drug at the bottom of the measuring cylinder and incomplete stirring, affecting the measurement results.

Method used

A new type of measuring cylinder for clinical trials is designed, integrating an aeration assembly, and aeration the inside of the measuring cylinder during the stirring process, using bubble impact to re-enter the solid medicines to the stirring range, speed up the dissolution speed, and design and seal through semi-splicing. The ring improves the stability and sealing of the measuring cylinder.

Benefits of technology

It effectively accelerates the dissolution rate of solid drugs, improves the sealing and stability of the measuring cylinder, and ensures the accuracy of experimental results and the quality of the solution.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model is suitable for the technical field of measuring cylinders, and provides a novel measuring cylinder for clinical tests. The measuring cylinder assembly comprises a measuring cylinder main body, a measuring cylinder base and a measuring cylinder head; the aeration assembly is arranged on the measuring cylinder base and is used for accelerating the dissolution of the solid medicine. Compared with the prior art, the medicine stirring device has the beneficial effects that when the medicine stirring device is used, the aeration component is arranged, so that the inside of the medicine stirring device is aerated through the aeration component while stirring is carried out, and solid medicines precipitated at the bottom move upwards along with the impact of bubbles and enter the working range of the stirring rod again; and when the rising gas impacts the solid medicine, the dissolving speed of the solid medicine can be further increased, so that the dissolving effect is better.
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Description

Technical Field

[0001] The utility model belongs to the technical field of measuring cylinders, in particular to a novel measuring cylinder for clinical trials. Background Art

[0002] A measuring cylinder is an instrument used to measure liquids and is mostly made of glass.

[0003] When conducting clinical trials, a variety of different liquids and solid drugs are often poured into a measuring cylinder for mixing to obtain a solution of a certain mass. During the mixing process, in order to increase the dissolution rate of the solid drug in the liquid and avoid liquid loss, which affects the final measurement result, a stirring rod is sometimes used to stir the drug directly in the measuring cylinder until the drug is completely dissolved. However, due to the slow dissolution rate of solid drugs, the solid drugs are easily precipitated at the bottom, resulting in incomplete dissolution due to lack of stirring.

[0004] Therefore, how to provide a new type of measuring cylinder for clinical trials is a problem that those skilled in the art need to solve urgently. Utility Model Content

[0005] The purpose of the utility model is to provide a novel measuring cylinder for clinical trials, aiming to solve the problems mentioned in the background technology.

[0006] The utility model is implemented as follows: a novel measuring cylinder for clinical trials, comprising:

[0007] The measuring cylinder as a whole comprises a measuring cylinder body, a measuring cylinder base and a measuring cylinder head;

[0008] An aeration component is arranged on the base of the measuring cylinder to accelerate the dissolution of solid medicines.

[0009] Preferably, the measuring cylinder body is spliced ​​in half, the measuring cylinder base is movably arranged at the bottom of the measuring cylinder body and movably plugged with the bottom of the measuring cylinder body, the measuring cylinder head is movably plugged at the top of the measuring cylinder body, a sealing ring is movably arranged at the lower end of the surface of the measuring cylinder head to seal the connection between the measuring cylinder body and the measuring cylinder head, and a cup mouth is fixedly installed on the side of the top of the measuring cylinder head.

[0010] Preferably, the aeration assembly includes an aeration tank, a temporary air storage tank, a limiting frame, a first one-way air valve and a movable sealing plate. The aeration tank and the temporary air storage tank are arranged inside the base of the measuring cylinder from the inside to the outside. An array of ventilation grooves is arranged between the aeration tank and the temporary air storage tank to connect the aeration tank and the temporary air storage tank. An exhaust duct is arranged in a circular array on the top of the inner side of the aeration tank and is connected to the measuring cylinder body. The limiting frame is fixedly installed on the top of the exhaust duct, and the movable sealing plate is movably installed on the top of the limiting frame. The first one-way air valve is fixedly installed on the right end of the temporary air storage tank. The top of the first one-way air valve is movably connected to a ventilation pipe, and the top of the ventilation pipe is fixedly connected to an inflatable air bag.

[0011] Preferably, a second one-way air valve is movably installed in the middle of the top of the inflatable airbag, and a connecting ring is fixedly installed on the edge of the top of the inflatable airbag.

[0012] Preferably, the exhaust passage is arranged in an S-shaped curved pipe shape as a whole.

[0013] Preferably, the surface of the measuring cylinder body is provided with bumps in an array from top to bottom, and a limiting block is installed in a circumferential array on the surface of the upper end of the measuring cylinder body to limit the sealing ring.

[0014] Compared with the prior art, the utility model has the following beneficial effects: when in use, by setting an aeration component, the interior is aerated through the aeration component while stirring, so that the solid medicine precipitated at the bottom moves upward with the impact of bubbles and re-enters the working range of the stirring rod, and the rising gas will further accelerate the dissolution rate of the solid medicine when it hits the solid medicine, so that the dissolution effect is better.

[0015] By splitting the measuring cylinder as a whole into a measuring cylinder body, a measuring cylinder head and a measuring cylinder base which are arranged in half, the measuring cylinder can be disassembled when cleaning, so that the inner wall can be cleaned conveniently. By setting a sealing ring, the connection between the measuring cylinder body and the measuring cylinder head is shielded and sealed, so that the overall stability of the measuring cylinder is improved, thereby making it more sealed and avoiding leakage of internal liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0017] Figure 1 A schematic diagram of the overall appearance structure of a new type of measuring cylinder for clinical trials provided by an embodiment of the utility model;

[0018] Figure 2A schematic diagram of a rear cross-sectional structure of a novel measuring cylinder for clinical trials provided in an embodiment of the utility model;

[0019] Figure 3 A new type of measuring cylinder for clinical trials provided by the utility model Figure 1 A schematic diagram of the enlarged structure of part A;

[0020] Figure 4 A new type of measuring cylinder for clinical trials provided by the utility model Figure 2 A schematic diagram of the enlarged structure of part B;

[0021] Figure 5 A new type of measuring cylinder for clinical trials provided by the utility model Figure 2 Schematic diagram of the enlarged structure of part C.

[0022] In the figure: 1-measuring cylinder body, 2-measuring cylinder base, 3-aeration groove, 4-venting groove, 5-temporary air storage groove, 6-exhaust duct, 7-limiting frame, 8-movable sealing plate, 9-first one-way air valve, 10-venting pipe, 11-inflatable air bag, 12-second one-way air valve, 13-connecting ring, 14-measuring cylinder head, 15-sealing ring, 16-cup mouth, 17-bump, 18-limiting block. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical solution and advantages of the utility model more clear, the utility model is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the utility model and are not used to limit the utility model.

[0024] The specific implementation of the present utility model is described in detail below in conjunction with specific embodiments.

[0025] like Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 FIG. 1 is a schematic diagram of a novel measuring cylinder for clinical trials provided by an embodiment of the utility model, comprising:

[0026] The measuring cylinder as a whole comprises a measuring cylinder body 1, a measuring cylinder base 2 and a measuring cylinder head 14;

[0027] An aeration component is arranged on the measuring cylinder base 2 to accelerate the dissolution of solid medicines.

[0028] In the embodiment of the utility model, when in use, the measuring cylinder body 1, the measuring cylinder base 2 and the measuring cylinder head 14 are spliced ​​together to form a measuring cylinder as a whole, and then the aeration component is started for aeration to accelerate the dissolution of the solid medicine.

[0029] like Figure 1 , Figure 2 and Figure 3 As shown, as a preferred embodiment of the utility model, the measuring cylinder body 1 is spliced ​​in half, the measuring cylinder base 2 is movably arranged at the bottom of the measuring cylinder body 1, and is movably plugged with the bottom of the measuring cylinder body 1, the measuring cylinder head 14 is movably plugged at the top of the measuring cylinder body 1, and a sealing ring 15 is movably arranged on the lower end of the surface of the measuring cylinder head 14 to seal the connection between the measuring cylinder body 1 and the measuring cylinder head 14, and a cup mouth 16 is fixedly installed on the side of the top of the measuring cylinder head 14.

[0030] In the embodiment of the utility model, when in use, the measuring cylinder body 1 that is split in half is spliced ​​together and then installed on the measuring cylinder base 2, and then the measuring cylinder head 14 is installed on the top of the measuring cylinder body 1, and then the sealing ring 15 is rotated downward to block and seal the connection between the measuring cylinder body 1 and the measuring cylinder head 14, thereby improving the overall stability of the measuring cylinder, thereby making it more sealed and avoiding leakage of the internal liquid.

[0031] like Figure 1 , Figure 2 , Figure 4 and Figure 5 As shown, as a preferred embodiment of the utility model, the aeration assembly includes an aeration tank 3, a temporary air storage tank 5, a limiting frame 7, a first one-way air valve 9 and a movable sealing plate 8, the aeration tank 3 and the temporary air storage tank 5 are arranged inside the measuring cylinder base 2 from the inside to the outside, and an array of ventilation grooves 4 are arranged between the aeration tank 3 and the temporary air storage tank 5 to communicate with the aeration tank 3 and the temporary air storage tank 5, an exhaust duct 6 is arranged in a top circumferential array on the inner side of the aeration tank 3, and is connected with the measuring cylinder body 1, the limiting frame 7 is fixedly installed on the top of the exhaust duct 6, the movable sealing plate 8 is movably installed on the top of the limiting frame 7, the first one-way air valve 9 is fixedly installed on the right end of the temporary air storage tank 5, the top of the first one-way air valve 9 is movably connected with a ventilation pipe 10, and the top of the ventilation pipe 10 is fixedly connected with an inflatable airbag 11.

[0032] In the embodiment of the utility model, when in use, by pressing the inflatable airbag 11, the internal gas enters the temporary gas storage tank 5, and then enters the aeration tank 3, so that the internal air pressure becomes larger, and then the movable sealing plate 8 is opened upward under the action of the air pressure, so that the excess gas passes through the exhaust duct 6 and forms bubbles around the movable sealing plate 8 to be discharged, so that the solid medicine inside is mobilized as the gas rises, so as to re-enter the working range of the stirring rod, and the rising gas will further accelerate its dissolution rate when it hits the solid medicine.

[0033] like Figure 2 and Figure 5 As shown, as a preferred embodiment of the utility model, a second one-way air valve 12 is movably installed in the middle of the top of the inflatable airbag 11, and a connecting ring 13 is fixedly installed on the edge of the top of the inflatable airbag 11.

[0034] In the embodiment of the utility model, when in use, the connecting ring 13 on the top of the inflatable airbag 11 and the second one-way air valve 12 are connected to a container filled with clean air, so that the quality and purity of the final solution can be guaranteed, making the final experimental result more accurate.

[0035] like Figure 2 and Figure 4 As shown, as a preferred embodiment of the present utility model, the exhaust passage 6 is arranged in an S-shaped curved pipe shape as a whole.

[0036] In the embodiment of the utility model, when in use, the exhaust passage 6 is arranged as an S-shaped curved pipe as a whole, so that the exhaust of gas is more concentrated and the entry of liquid is avoided.

[0037] like Figure 1 and Figure 2 As shown, as a preferred embodiment of the utility model, the surface of the measuring cylinder body 1 is provided with bumps 17 in an array from top to bottom, and the surface circumferential array of the upper end of the measuring cylinder body 1 is provided with limiting blocks 18 to limit the sealing ring 15.

[0038] In the embodiment of the utility model, when in use, the protrusion 17 is used to increase the gripping feeling of the measuring cylinder body 1, so that the gripping effect is better, and the limit block 18 is provided to reduce the movement of the sealing ring 15.

[0039] The above embodiment of the utility model provides a novel measuring cylinder for clinical trials. When in use, the measuring cylinder body 1 divided into two halves is spliced ​​together, then installed on the measuring cylinder base 2, and then the measuring cylinder head 14 is installed on the top of the measuring cylinder body 1;

[0040] Then, the sealing ring 15 is rotated downward until it contacts the stop block 18, thereby shielding and sealing the connection between the measuring cylinder body 1 and the measuring cylinder head 14, thereby improving the overall stability of the measuring cylinder, thereby making it more airtight and preventing leakage of the internal liquid;

[0041] Then put the liquid medicine and solid medicine into the bottled measuring cylinder and stir;

[0042] When stirring, the inflatable airbag 11 can be pressed to allow the internal gas to enter the temporary gas storage groove 5 at the inner edge of the measuring cylinder base 2 through the vent pipe 10 and the first one-way air valve 9, and then enter the aeration tank 3 through the vent groove 4, thereby increasing the internal gas pressure;

[0043] Then, the movable sealing sheet 8 overcomes the pressure of the liquid under the action of the air pressure and opens upward, so that the excess gas passes through the exhaust channel 6 and forms bubbles around the movable sealing sheet 8 to be discharged, so that the solid medicine inside moves with the rising of the gas, so as to re-enter the working range of the stirring rod, and when the rising gas hits the solid medicine, it will further accelerate its dissolution speed;

[0044] As the excess gas is discharged, the movable sealing sheet 8 is re-closed with the limit frame 7 under the action of hydraulic pressure, thereby preventing the liquid from entering the aeration tank 3, affecting the subsequent cleaning work and causing the leakage of the liquid medicine, thus affecting the final experimental results.

[0045] Considering the quality and purity of the solution, the connecting ring 13 and the second one-way air valve 12 on the top of the inflatable airbag 11 can be connected to a container filled with clean air, so that the quality of the final solution can be guaranteed and the final experimental result can be more accurate.

[0046] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A new type of measuring cylinder for clinical trials, characterized in that: include; The measuring cylinder as a whole comprises a measuring cylinder body, a measuring cylinder base and a measuring cylinder head; An aeration component, which is arranged on the base of the measuring cylinder to accelerate the dissolution of solid medicines; The aeration assembly includes an aeration tank, a temporary air storage tank, a limiting frame, a first one-way air valve and a movable sealing plate. The aeration tank and the temporary air storage tank are arranged inside the base of the measuring cylinder from the inside to the outside. An array of ventilation grooves is arranged between the aeration tank and the temporary air storage tank to connect the aeration tank and the temporary air storage tank. An exhaust duct is arranged in an array on the top circumference of the inner side of the aeration tank and is connected to the measuring cylinder body. The limiting frame is fixedly installed on the top of the exhaust duct. The movable sealing plate is movably installed on the top of the limiting frame. The first one-way air valve is fixedly installed on the right end of the temporary air storage tank. The top of the first one-way air valve is movably connected to a ventilation pipe, and the top of the ventilation pipe is fixedly connected to an inflatable airbag.

2. A new type of measuring cylinder for clinical trials according to claim 1, characterized in that: The measuring cylinder body is spliced ​​in half, the measuring cylinder base is movably arranged at the bottom of the measuring cylinder body and movably plugged with the bottom of the measuring cylinder body, the measuring cylinder head is movably plugged at the top of the measuring cylinder body, a sealing ring is movably arranged at the lower end of the surface of the measuring cylinder head to seal the connection between the measuring cylinder body and the measuring cylinder head, and a cup mouth is fixedly installed on the side of the top of the measuring cylinder head.

3. A new type of measuring cylinder for clinical trials according to claim 1, characterized in that: A second one-way air valve is movably installed in the middle of the top of the inflatable airbag, and a connecting ring is fixedly installed at the edge of the top of the inflatable airbag.

4. A new type of measuring cylinder for clinical trials according to claim 1, characterized in that: The exhaust duct is arranged in an S-shaped curved pipe shape as a whole.

5. A new type of measuring cylinder for clinical trials according to claim 2, characterized in that: The surface of the measuring cylinder body is provided with bumps in an array from top to bottom, and a limiting block is installed in a circumferential array on the surface of the upper end of the measuring cylinder body to limit the sealing ring.