Biomarker detection equipment for biotechnology

Abstract

The utility model belongs to the field of biotechnology, and particularly relates to biomarker detection equipment for biotechnology, which comprises a detection box, a placement groove is formed in the surface of the top of the detection box, a top block is fixedly mounted in the placement groove, a liquid inlet is formed in the surface of the top block, a detection tank is fixedly connected to the bottom of the top block, a biosensor is fixedly mounted on the surface of the detection tank, and an intelligent valve is fixedly mounted at the bottom of the detection tank. Through the arrangement of the placing groove, a sample cup can be conveniently placed, the area of a liquid outlet formed in the bottom of the sample cup is the same as that of the bottom of the ejector block, perfect clamping can be achieved, the ejector block is a rubber product as a whole, sealing can be well kept when the ejector block makes contact with a sealing ring in the liquid outlet, and therefore leakage waste of a biological extracting solution is reduced; through the arrangement of the liquid inlet, the biological extracting solution can be conveniently guided into the detection tank at the bottom, and through the arrangement of the detection tank, the biological extracting solution can be conveniently detected.

Description

Technical Field

[0001] The utility model relates to the field of biotechnology, in particular to a biomarker detection device for biotechnology. Background Art

[0002] Biomarkers refer to biochemical indicators that can mark changes or possible changes in the structure or function of systems, organs, tissues, cells and subcellular structures, and have very wide applications.

[0003] For example, a microbial detection device with a publication number of CN219260026U includes a cabinet, an incubator, a drive device, a command input device and a controller. The incubator is installed in the cabinet in a drawer-like manner. The incubator has multiple placement positions, which are used to place culture containers carrying samples. The incubator has an open position and an embedded position relative to the cabinet. The drive device is installed in the cabinet and connected to the incubator. The drive device is used to drive the incubator to move between the open position and the embedded position. The command input device is used to receive user commands. The controller is electrically connected to the drive device and the command input device. The controller is used to control the drive device to drive the incubator to move according to the user's command. The proposed microbial detection device, by arranging a drive device between the cabinet and the incubator, the user only needs to input the user's command through the command input device, and the controller can control the drive device according to the command to move the incubator from the embedded position to the open position, or move the incubator from the open position to the embedded position, which greatly facilitates the staff.

[0004] However, based on the working principle proposed in the above patent, the applicant believes that although the above device can facilitate the use of the staff to a certain extent, in actual use, the above device has a weak ability to detect biomarkers and cannot identify and detect the components inside the biological extract well, which is easy to affect the detection quality of the biological extract when used.

[0005] Therefore, in order to solve the above problems, a biomarker detection device for biotechnology is proposed. Utility Model Content

[0006] The technical problem to be solved by the utility model is that the prior art has the disadvantage of weak detection capability for biological extracts, for which we propose a biomarker detection device for biotechnology.

[0007] The utility model solves the technical problem by adopting the following technical solution: a biomarker detection device for biotechnology, comprising a detection box; a placement groove is provided on the surface of the top of the detection box, a top block is fixedly installed inside the placement groove, a liquid inlet is provided on the surface of the top block, a detection tank is fixedly connected to the bottom of the top block, a biosensor is fixedly installed on the surface of the detection tank, and an intelligent valve is fixedly installed on the bottom of the detection tank.

[0008] Preferably, a liquid storage tank is fixedly mounted on the bottom of the detection box, the liquid storage tank is communicated with the detection box, and a first glass window is arranged on the back of the liquid storage tank.

[0009] Preferably, liquid outlet pipes are provided on both sides of the first glass window, side panels are fixedly installed on both sides of the liquid storage box and the detection box, and a support plate is fixedly installed on the bottom of the side panel.

[0010] Preferably, a sample cup is movably mounted inside the placement groove, a holding frame is fixedly mounted at the bottom of the inner cavity of the sample cup, and liquid permeable openings are provided around the holding frame.

[0011] Preferably, a rotary spring is fixedly mounted on the top of the lifting frame, a rubber sealing plate is fixedly connected to the bottom of the rotary spring, a sealing ring is provided at the bottom of the rubber sealing plate, and a liquid outlet is provided at the bottom of the inner cavity of the sample cup.

[0012] Preferably, a control box is fixedly mounted on the front of the detection box, a display screen is fixedly mounted on the surface of the control box, and operation buttons are arranged on both sides of the display screen.

[0013] Preferably, a protective door is movably installed on the front of the bottom of the display screen, a second glass window is provided on the surface of the protective door, and a pull ring is fixedly installed on the right side of the second glass window.

[0014] The beneficial effects of the utility model are:

[0015] 1. The utility model is convenient for placing the sample cup by setting the placement groove. The area of ​​the liquid outlet arranged at the bottom of the sample cup is the same as the area of ​​the bottom of the top block, which can achieve perfect insertion. The top block as a whole is a rubber product. When it contacts the sealing ring inside the liquid outlet, it can maintain a good seal, thereby reducing the waste of biological extract leakage. The setting of the liquid inlet is convenient for guiding the biological extract to the inside of the detection tank at the bottom. The setting of the detection tank is convenient for detecting the biological extract. A biosensor is arranged inside the detection tank. The biosensor uses biological molecules or cells in the biological system to detect biomarkers. For example, the enzyme-linked immunosorbent assay can be used to detect proteins in the blood, such as hepatitis virus, H IV, etc. The setting of the intelligent valve is convenient for the user to control the outflow of the internal biological extract.

[0016] 2. The utility model is convenient for collecting the biological extract after detection through the arrangement of the liquid storage box, and convenient for the user to observe the internal capacity of the liquid storage box through the arrangement of the first glass window, and convenient for supporting the whole device through the arrangement of the side plate and the support plate, and convenient for the user to guide the biological extract to be detected into the detection box through the arrangement of the sample cup, and convenient for the user to guide the biological extract to be detected into the detection box through the arrangement of the sample cup, and a rubber sealing plate is installed at the bottom of the sample cup through a rotary spring, and under normal conditions, the rubber sealing plate is in close contact with the sealing ring on the surface of the liquid outlet, so that the liquid outlet is completely sealed, and when the sample cup is placed in the placement groove, the top block will lift the rubber sealing plate, and a gap will appear at the liquid outlet, so that the biological extract can enter the detection box along the liquid inlet and the liquid permeable port, and convenient for the user to collect the data after detection through the arrangement of the display screen, convenient for the user to control the electrical property of the device through the arrangement of the operation button, and convenient for the user to open the protective door through the arrangement of the pull ring. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0018] Figure 1 It is a frontal perspective schematic diagram of the overall structure of the utility model;

[0019] Figure 2 It is a three-dimensional back view of the overall structure of the utility model;

[0020] Figure 3 It is a bottom-up stereoscopic schematic diagram of the overall structure of the utility model;

[0021] Figure 4 It is a cross-sectional enlarged stereoscopic schematic diagram of the sample cup structure of the utility model;

[0022] Figure 5 It is a partial enlarged schematic diagram of the detection box structure of the utility model.

[0023] In the figure: 1. detection box; 2. placement slot; 3. top block; 4. liquid inlet; 5. detection tank; 6. biosensor; 7. smart valve; 8. liquid storage tank; 9. first glass window; 10. liquid outlet pipe; 11. side panel; 12. support plate; 13. sample cup; 14. lifting frame; 15. liquid permeable port; 16. rotary spring; 17. rubber sealing plate; 18. sealing ring; 19. liquid outlet; 20. control box; 21. display screen; 22. operation button; 23. protective door; 24. second glass window; 25. pull ring. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] The following is combined with Figure 1-5 To further explain this application in detail,

[0026] The present application embodiment discloses a biomarker detection device for biotechnology. Figure 4 and Figure 5 A biomarker detection device for biotechnology includes a detection box 1; a placement groove 2 is provided on the surface of the top of the detection box 1, a top block 3 is fixedly installed inside the placement groove 2, a liquid inlet 4 is provided on the surface of the top block 3, a detection tank 5 is fixedly connected to the bottom of the top block 3, a biosensor 6 is fixedly installed on the surface of the detection tank 5, and a smart valve 7 is fixedly installed at the bottom of the detection tank 5; the placement groove 2 is convenient for placing a sample cup 13, the area of ​​the liquid outlet 19 provided at the bottom of the sample cup 13 is the same as the area of ​​the bottom of the top block 3, and a perfect insertion can be achieved, and the top block 3 is a rubber product as a whole, when it contacts with the sealing ring 18 inside the liquid outlet 19, it can maintain a good seal, thereby reducing the waste of biological extract leakage, and the biological extract is conveniently guided to the inside of the detection tank 5 at the bottom through the liquid inlet 4, and the biological extract is conveniently detected through the detection tank 5, and a biosensor 6 is provided inside the detection tank 5, and the biosensor 6 uses biological molecules or cells in the biological system to detect biomarkers. For example, the enzyme-linked immunosorbent assay can be used to detect proteins in the blood, such as hepatitis virus, H IV, etc., through the intelligent valve 7, it is convenient for the user to control the outflow of the internal biological extract.

[0027] Reference Figure 4 and Figure 1 A liquid storage tank 8 is fixedly installed at the bottom of the detection box 1, and the liquid storage tank 8 is connected to the detection box 1. A first glass window 9 is provided on the back of the liquid storage tank 8; the liquid storage tank 8 is convenient for collecting the biological extract after detection, and the first glass window 9 is convenient for the user to observe the internal capacity of the liquid storage tank 8.

[0028] Reference Figure 1 and Figure 4 Liquid outlet pipes 10 are provided on both sides of the first glass window 9, side panels 11 are fixedly installed on both sides of the liquid storage box 8 and the detection box 1, and support plates 12 are fixedly installed on the bottom of the side panels 11; the side panels 11 and the support plates 12 are used to support the entire device.

[0029] Reference Figure 2 and Figure 1 A sample cup 13 is movably mounted on the inner side of the placement groove 2, a lifting frame 14 is fixedly mounted on the bottom of the inner cavity of the sample cup 13, and liquid permeable ports 15 are opened around the lifting frame 14; the sample cup 13 facilitates the user to guide the biological extract to be tested into the detection box 1.

[0030] Reference Figure 2 and Figure 3 A rotary spring 16 is fixedly installed on the top of the lifting frame 14, and a rubber sealing plate 17 is fixedly connected to the bottom of the rotary spring 16. A sealing ring 18 is arranged at the bottom of the rubber sealing plate 17, and a liquid outlet 19 is opened at the bottom of the inner cavity of the sample cup 13; a rubber sealing plate 17 is installed at the bottom of the sample cup 13 through the rotary spring 16. Under normal conditions, the rubber sealing plate 17 is in close contact with the sealing ring 18 on the surface of the liquid outlet 19, thereby completely sealing the liquid outlet 19. When the sample cup 13 is placed in the placement groove 2, the top block 3 will lift the rubber sealing plate 17, and a gap will appear at the liquid outlet 19, so that the biological extract can enter the detection box 1 along the liquid inlet 4 and the liquid permeable port 15.

[0031] Reference Figure 1 and Figure 2 A control box 20 is fixedly installed on the front of the detection box 1, and a display screen 21 is fixedly installed on the surface of the control box 20. Operation buttons 22 are arranged on both sides of the display screen 21; the display screen 21 is convenient for users to collect data after detection, and the operation buttons 22 are convenient for users to electrically control the device.

[0032] Reference Figure 1 and Figure 3 A protective door 23 is movably installed on the front of the bottom of the display screen 21, a second glass window 24 is provided on the surface of the protective door 23, and a pull ring 25 is fixedly installed on the right side of the second glass window 24; the pull ring 25 is convenient for the user to open the protective door 23.

[0033] Working principle: When the device is used, the biological extract is first guided into the sample cup 13. A rubber sealing plate 17 is installed at the bottom of the sample cup 13 through a rotary spring 16. Under normal conditions, the rubber sealing plate 17 is in close contact with the sealing ring 18 on the surface of the liquid outlet 19, thereby completely sealing the liquid outlet 19. When the sample cup 13 is placed in the placement slot 2, the top block 3 will lift the rubber sealing plate 17, and a gap will appear at the liquid outlet 19. The biological extract can enter the detection box 1 along the liquid inlet 4 and the liquid permeable port 15. The biological extract is easily detected through the detection tank 5. A biosensor 6 is arranged inside the detection tank 5. The biosensor 6 uses biological molecules or cells in the biological system to detect biomarkers. For example, the enzyme-linked immunosorbent assay can be used to detect proteins in the blood, such as hepatitis virus, HIV, etc. The intelligent valve 7 is convenient for the user to control the outflow of the internal biological extract.

[0034] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments, and the above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, and these changes and improvements fall within the scope of the utility model to be protected.

Claims

1. A biomarker detection device for biotechnology, characterized in that: The invention comprises a detection box (1); a placement groove (2) is provided on the top surface of the detection box (1); a top block (3) is fixedly installed inside the placement groove (2); a liquid inlet (4) is provided on the surface of the top block (3); a detection tank (5) is fixedly connected to the bottom of the top block (3); a biosensor (6) is fixedly installed on the surface of the detection tank (5); and a smart valve (7) is fixedly installed on the bottom of the detection tank (5).

2. A biomarker detection device for biotechnology according to claim 1, characterized in that: A liquid storage tank (8) is fixedly mounted on the bottom of the detection box (1); the liquid storage tank (8) is connected to the detection box (1); and a first glass window (9) is provided on the back of the liquid storage tank (8).

3. A biomarker detection device for biotechnology according to claim 2, characterized in that: Liquid outlet pipes (10) are provided on both sides of the first glass window (9), side panels (11) are fixedly installed on both sides of the liquid storage box (8) and the detection box (1), and a support plate (12) is fixedly installed on the bottom of the side panel (11).

4. A biomarker detection device for biotechnology according to claim 1, characterized in that: A sample cup (13) is movably mounted inside the placement groove (2), a lifting frame (14) is fixedly mounted at the bottom of the inner cavity of the sample cup (13), and liquid permeable openings (15) are provided around the lifting frame (14).

5. A biomarker detection device for biotechnology according to claim 4, characterized in that: A revolving spring (16) is fixedly mounted on the top of the lifting frame (14), a rubber sealing plate (17) is fixedly connected to the bottom of the revolving spring (16), a sealing ring (18) is arranged at the bottom of the rubber sealing plate (17), and a liquid outlet (19) is provided at the bottom of the inner cavity of the sample cup (13).

6. A biomarker detection device for biotechnology according to claim 1, characterized in that: A control box (20) is fixedly mounted on the front of the detection box (1), a display screen (21) is fixedly mounted on the surface of the control box (20), and operation buttons (22) are arranged on both sides of the display screen (21).

7. A biomarker detection device for biotechnology according to claim 6, characterized in that: A protective door (23) is movably installed on the front of the bottom of the display screen (21), a second glass window (24) is arranged on the surface of the protective door (23), and a pull ring (25) is fixedly installed on the right side of the second glass window (24).

Images