Pipetting workstation

Abstract

The utility model provides a pipetting workstation and relates to the technical field of medical instruments. The pipetting workstation comprises a rack, a multi-gun-head pipettor assembly, a pipetting device and a carrier device, the pipetting device comprises an X moving assembly, a Y moving assembly and a Z moving assembly, the Z moving assembly is fixedly connected to the rack, the multi-tip pipettor assembly is in transmission connection with the Z moving assembly, the Z moving assembly drives the multi-tip pipettor assembly to ascend and descend in the Z direction, the Y moving assembly comprises a Y sliding plate and a Y power assembly, the X moving assembly is connected to the Y sliding plate, the Y sliding plate is movably connected to the rack, and the Y sliding plate is movably connected to the rack. The Y power assembly is in transmission connection with the Y sliding plate to drive the Y sliding plate to move in the Y direction; the carrier device is connected to the X moving assembly and used for containing the gun head box and the carrier so as to be matched with the multi-gun-head pipettor assembly to complete gun head replacement or pipetting. The pipetting work station can improve the adjustment precision in the Y direction, so that the pipetting convenience is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical equipment, in particular to a liquid transfer workstation. Background Art

[0002] The pipetting workstation is mainly used for liquid handling. It has the characteristics of high throughput, high precision, high automation, high compatibility, and high cost performance. It has functions such as continuous gradient dilution, liquid distribution, addition, and combination between 96 microplates. It is widely used in large-scale pipetting processing such as genomics research, drug screening, and protein analysis and processing.

[0003] Since the pipetting head of the 96-channel pipette is large and heavy, the existing 96-channel pipetting workstation can only achieve position adjustment in the X and Z directions. Therefore, during the pipetting process, if the carrier is replaced, in order to ensure that the gun tip is aligned with the center position of the liquid hole on the carrier, the carrier and the carrier need to be manually adjusted in the Y direction, resulting in poor adjustment accuracy and a relatively troublesome pipetting process. Utility Model Content

[0004] The utility model aims to provide a liquid transfer workstation, which can improve the adjustment accuracy in the Y direction, thereby improving the convenience of liquid transfer.

[0005] To achieve this purpose, the utility model adopts the following technical solutions:

[0006] Liquid handling station, including:

[0007] Multi-tip pipette assembly;

[0008] frame;

[0009] The liquid transfer device comprises an X-moving assembly, a Y-moving assembly and a Z-moving assembly, wherein the Z-moving assembly is fixedly connected to the frame, the multi-gun tip pipette assembly is transmission-connected to the Z-moving assembly, the Z-moving assembly drives the multi-gun tip pipette assembly to move up and down along the Z direction, the Y-moving assembly comprises a Y-slide plate and a Y-power assembly, the X-moving assembly is transmission-connected to the Y-slide plate, the Y-slide plate is movably connected to the frame, and the Y-power assembly is transmission-connected to the Y-slide plate to drive the Y-slide plate to move along the Y direction;

[0010] A carrier device connected to the X-moving assembly is used to place the tip box and the carrier to cooperate with the multi-tip pipette assembly to complete the tip replacement or pipetting

[0011] As a further technical solution, the Y moving assembly further includes a Y slide rail, and the Y power assembly includes a Y driving member and a fixing frame;

[0012] One of the Y driving member and the fixed frame is connected to the frame, and the other is connected to the Y slide plate. The output shaft of the Y driving member is transmission-connected to the fixed frame. The Y slide rail is fixedly arranged on the frame and extends along the Y direction. The Y slide plate is slidably connected to the Y slide rail.

[0013] As a further technical solution, the Y moving component also includes a position sensor and a controller. The position sensor is arranged on one side of the Y slide plate to sense the position of the Y slide plate. The position sensor and the Y driving member are both connected to the controller.

[0014] As a further technical solution, the Y moving component also includes an auxiliary sensing component, one end of which is fixedly connected to the Y slide board, and the position sensor cooperates with the other end of the auxiliary sensing component. The position sensor senses the position of the auxiliary sensing component and sends a signal to the controller.

[0015] As a further technical solution, the Y moving assembly also includes two supporting pallets, both of which are fixedly connected to the frame and fixedly arranged on both sides of the Y slide at intervals along the X direction, and the Z moving assembly is fixedly connected to the two supporting pallets.

[0016] As a further technical solution, the X moving assembly includes an X power assembly and an X slider support plate, the X power assembly is arranged on the Y slider, the X slider support plate is connected to the Y slider, the carrier device is movably connected to the X slider support plate along the X direction, and is transmission-connected to the X power assembly.

[0017] As a further technical solution, the carrier device includes a carrier body, and a rack and an X slide rail extending along the X direction are arranged on the end surface of the carrier body close to the X slider support plate, and the X power assembly includes an X driving member and a gear;

[0018] The carrier body is slidably connected to the X slider support plate through the X slide rail, and the gear transmission is connected to the output shaft of the X driving member and meshes with the rack.

[0019] As a further technical solution, the carrier device also includes an adjustment mechanism, and a first opening for placing a gun tip box is provided on the carrier body. The adjustment mechanism is connected to the carrier body and is located on at least one side of the first opening. The adjustment mechanism cooperates with the first opening to limit the relative position of the gun tip box.

[0020] As a further technical solution, the adjustment mechanism includes an adjustment limiter and an elastic clamping assembly, the adjustment limiter is arranged on one side of the first opening, and the elastic clamping assembly is arranged on the adjustment limiter and abuts against the gun tip box.

[0021] As a further technical solution, the elastic clamping assembly includes an elastic member and an abutment member, a guide groove is provided on the adjustment limit member, the first end of the elastic member is connected to the bottom wall of the guide groove, the abutment member is connected to the second end of the elastic member and abuts against the gun tip box.

[0022] Compared with the prior art, the liquid transfer workstation provided by the utility model has the following technical advantages:

[0023] Since the frame is provided with a Y slide movably, and a Y power assembly connected to the Y slide in transmission, and since the X moving assembly is connected to the Y slide in transmission, and the Z moving assembly is fixedly connected to the frame; in the process of using the pipetting workstation for pipetting, after replacing a new carrier, the relative position of the carrier and the multi-gun tip pipette assembly in the X direction can be adjusted by the X moving assembly, and the relative position of the multi-gun tip pipette assembly and the carrier in the Z direction can be adjusted by the Z moving assembly; at the same time, the Y power assembly is started, and the Y power assembly drives the Y slide and the X moving assembly to slide in the Y direction, so as to adjust the relative position of the carrier device and the multi-gun tip pipette assembly in the Y direction, so as to ensure that the gun heads in the multi-gun tip pipette assembly are aligned with the center position of the liquid hole on the carrier. In the whole process, the relative position of the carrier device can be adjusted without manual adjustment of the carrier device in the Y direction, thereby improving the adjustment accuracy in the Y direction and improving the convenience of pipetting. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is an isometric structural diagram of a liquid transfer workstation provided by an embodiment of the utility model;

[0025] Figure 2 It is a partial structural schematic diagram of a liquid transfer workstation provided by an embodiment of the utility model;

[0026] Figure 3 This is a schematic diagram of the structure of the Y moving component in the liquid transfer workstation provided by the embodiment of the utility model. Figure 1 ;

[0027] Figure 4 This is a schematic diagram of the structure of the Y moving component in the liquid transfer workstation provided by the embodiment of the utility model. Figure 2 ;

[0028] Figure 5 This is a partial structural diagram of the pipetting device in the pipetting workstation provided by the embodiment of the utility model Figure 1 ;

[0029] Figure 6 This is a partial structural diagram of the pipetting device in the pipetting workstation provided by the embodiment of the utility model Figure 2 ;

[0030] Figure 7 It is a structural schematic diagram of a carrier device in a liquid transfer workstation provided by an embodiment of the utility model;

[0031] Figure 8 It is a partial enlarged view of the carrier device in the liquid transfer workstation provided by the embodiment of the utility model;

[0032] Fig. 9 It is a structural schematic diagram of an elastic clamping assembly in a liquid transfer workstation provided by an embodiment of the utility model;

[0033] Fig.10 It is a structural schematic diagram of another implementation manner of the elastic clamping assembly in the liquid transfer workstation provided by an embodiment of the utility model.

[0034] In the figure:

[0035] 10. Multi-tip pipette assembly; 20. Tip box; 30. Carrier;

[0036] 100, rack;

[0037] 210, X moving assembly; 211, X power assembly; 2111, X driving member; 2112, X pulley; 212, X slider support plate; 220, Y moving assembly; 221, Y slide plate; 222, Y power assembly; 2221, Y driving member; 2222, fixed frame; 223, Y slide rail; 224, position sensor; 225, auxiliary sensing member; 226, support support plate; 230, Z moving assembly; 231, Z driving member; 232, Z slide rail; 233, Z lead screw; 234, electrical assembly;

[0038] 300, carrier device; 310, carrier body; 311, rack; 312, X-slide rail; 313, first opening; 314, second opening; 320, adjustment limit member; 321, first side wall; 330, elastic clamping assembly; 331, elastic member; 332, abutting member; 333, guide groove; 334, auxiliary member. DETAILED DESCRIPTION

[0039] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It is to be understood that the specific embodiments described herein are only used to explain the present invention, rather than to limit the present invention. It should also be noted that, for ease of description, only the parts related to the present invention, rather than all structures, are shown in the accompanying drawings.

[0040] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0041] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0042] In the description of this embodiment, the terms "upper", "lower", "right", etc., are based on the directions or positions shown in the drawings, and are only for the convenience of description and simplified operation, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first" and "second" are only used to distinguish in the description and have no special meaning.

[0043] Specific combination Figures 1 to 10 As shown, the pipetting workstation provided in this embodiment is used to cooperate with the multi-gun tip pipette assembly 10 to complete pipetting and replace the gun tip. The specific pipetting workstation includes a frame 100, a pipetting device and a carrier device 300: the pipetting device includes an X-moving component 210, a Y-moving component 220 and a Z-moving component 230: the Z-moving component 230 is fixedly connected to the frame 100, and is used to install the multi-gun tip pipette assembly 10: the Y-moving component 220 includes a Y-slide plate 221 and a Y-power assembly 222, the X-moving component 210 is transmission-connected to the Y-slide plate 221, the Y-slide plate 221 is movably connected to the frame 100, and the Y-power assembly 222 is transmission-connected to the Y-slide plate 221 to drive the Y-slide plate 221 to move along the Y direction; the carrier device 300 is transmission-connected to the X-moving component 210, and is used to place the gun tip box 20 and the carrier 30, so as to cooperate with the multi-gun tip pipette assembly 10 to complete the replacement of the gun tip or pipetting.

[0044] Since the frame 100 is movably provided with a Y slide 221, and is provided with a Y power assembly 222 that is transmission-connected to the Y slide 221, and since the X moving assembly 210 is transmission-connected to the Y slide 221, the Z moving assembly 230 is fixedly connected to the frame 100; in the process of using the pipetting workstation for pipetting, after replacing a new carrier 30, the relative position of the carrier 30 and the multi-gun tip pipette assembly 10 in the X direction can be adjusted by the X moving assembly 210, and the relative position of the multi-gun tip pipette assembly 10 and the carrier 30 in the Z direction can be adjusted by the Z moving assembly 230; at the same time, the Y power assembly 222 is started, and the Y power assembly 222 drives the Y slide 221 and the X moving assembly 210 to slide in the Y direction, thereby adjusting the relative position of the carrier device 300 and the multi-gun tip pipette assembly 10 in the Y direction, thereby ensuring that the gun tips in the multi-gun tip pipette assembly 10 are aligned with the center position of the liquid hole on the carrier 30. During the whole process, the relative position of the carrier device 300 can be adjusted without manual adjustment of the carrier device 300 in the Y direction, thereby improving the adjustment accuracy in the Y direction and the convenience of pipetting.

[0045] Preferably, the Y moving component 220 also includes a Y slide rail 223, and the Y power assembly 222 includes a Y driving member 2221 and a fixed frame 2222; one of the Y driving member 2221 and the fixed frame 2222 is connected to the frame 100, and the other is connected to the Y slide plate 221, the output shaft of the Y driving member 2221 is transmission-connected to the fixed frame 2222, the Y slide rail 223 is fixedly arranged on the frame 100 and extends along the Y direction, and the Y slide plate 221 is slidingly connected to the Y slide rail 223.

[0046] Specific combination Figures 2 to 4 As shown, two Y slide rails 223 are provided, and the two Y slide rails 223 are spaced apart along the X direction, and the two Y slide rails 223 are both slidably matched with the Y slide plate 221. In this embodiment, the fixed frame 2222 is connected to the frame 100, the Y driving member 2221 is connected to the Y slide plate 221, and the output shaft of the Y driving member 2221 is transmission-connected with the fixed frame 2222; when the relative position of the Y slide plate 221 needs to be adjusted, the Y driving member 2221 is started, and the output shaft rotates forward and reversely to change the relative position between the Y driving member 2221 and the fixed frame 2222, thereby driving the Y slide plate 221 to change the relative position with the frame 100 along the Y direction, and then adjusting the relative position of the carrier device 300 and the multi-gun tip pipette assembly 10 in the Y direction, thereby ensuring that the gun tips in the multi-gun tip pipette assembly 10 are aligned with the center position of the liquid hole on the carrier 30.

[0047] In some other embodiments, the Y driving member 2221 may be connected to the frame 100, the fixing frame 2222 may be connected to the Y slide plate 221, and the output shaft of the Y driving member 2221 may be in driving connection with the fixing frame 2222. Alternatively, the Y driving member 2221 may be directly configured as a push rod motor, the fixed end of the push rod motor may be directly fixedly connected to the frame 100, the output shaft of the push rod motor may be in driving connection with the Y slide plate 221, and the Y slide plate 221 may be driven to move along the Y direction as the output shaft of the push rod motor is extended or retracted.

[0048] Preferably, the Y moving component 220 further includes a position sensor 224 and a controller. The position sensor 224 is disposed on one side of the Y slide 221 for sensing the position of the Y slide 221. The position sensor 224 and the Y driving member 2221 are both connected to the controller.

[0049] Specific combination Figure 4 As shown, the position sensor 224 is fixedly arranged on the frame 100 and is located on one side of the Y slide 221, and is used to monitor the relative position of the Y slide 221 and transmit it to the controller. After replacing a new carrier 30, the controller sends an adjustment signal to the Y drive 2221, and the Y drive 2221 receives the adjustment signal and starts, thereby driving the Y slide 221 to slide, so as to adjust the relative position of the carrier device 300 and the multi-gun tip pipette assembly 10; when the position sensor 224 senses that the Y slide 221 is adjusted to the target position, the position sensor 224 sends a stop signal to the controller, and the controller receives the stop signal and controls the Y drive to stop running, thereby ensuring that the gun tips in the multi-gun tip pipette assembly 10 are accurately aligned with the center position of the liquid hole on the carrier 30.

[0050] Preferably, the Y moving component 220 also includes an auxiliary sensing component 225, one end of which is fixedly connected to the Y slide 221, and the position sensor 224 cooperates with the other end of the auxiliary sensing component 225 for sensing. The position sensor 224 senses the position of the auxiliary sensing component 225 and sends a signal to the controller.

[0051] Specific combination Figure 4 As shown, the position sensor 224 is configured as a photoelectric switch, and the auxiliary sensing member 225 is configured as a plate. The first end of the auxiliary sensing member 225 is fixedly connected to the side wall of the Y slide 221, and the second end is tilted in the direction away from the side wall of the Y slide 221. The auxiliary sensing member 225 moves with the sliding of the Y slide 221. During the Y-direction position adjustment process, when the photoelectric switch senses the auxiliary sensing member 225, the photoelectric switch sends a stop signal to the controller, and the Y driving member 2221 stops operating. The auxiliary sensing member 225 cooperates with the photoelectric switch to improve the sensing accuracy of the position sensor 224, thereby improving the adjustment accuracy of the Y slide 221.

[0052] Preferably, the Y moving assembly 220 further includes two supporting pallets 226 , which are fixedly connected to the frame 100 and fixedly arranged at intervals on both sides of the Y slide plate 221 along the X direction, and the Z moving assembly 230 is fixedly connected to the two supporting pallets 226 .

[0053] Specific combination Figure 6 As shown, the Z moving component 230 is fixedly connected to the two supporting plates 226, which ensures the connection stability and connection strength between the Z moving component 230 and the frame 100, while preventing the Z moving component 230 from sliding against the Y slide 221. At the same time, the Z moving component 230 is located above the Y moving component 220, which can improve the space utilization of the pipetting workstation.

[0054] In this embodiment, the specific structure of the Z moving assembly 230 is as follows: the Z moving assembly 230 includes a Z driving member 231, a Z slide rail 232, a Z screw rod 233 and an electrical assembly 234. The first end of the Z slide rail 232 is directly or indirectly fixedly connected to the two support plates 226, and the second end extends upward, and the Z slide rail 232 is vertically arranged with the frame 100, the Z driving member 231 is arranged at the second end of the Z slide rail 232, and is transmission-connected with the first end of the Z screw rod 233, and the multi-gun tip pipette assembly 10 is directly or indirectly transmission-connected to the second end of the Z screw rod 233. When it is necessary to adjust the relative position of the multi-gun tip pipette assembly 10 in the Z direction, the Z driving member 231 is started, and as the output shaft of the Z driving member 231 rotates forward or reversely, the Z screw rod 233 is driven forward or reversed, thereby driving the multi-gun tip pipette assembly 10 to reciprocate along the Z direction, thereby changing the relative position of the multi-gun tip pipette assembly 10 in the Z direction. In addition, the electrical assembly 234 is connected to the other side of the Z slide rail 232 to ensure the use effect while reducing the overall volume of the Z moving component 230.

[0055] Preferably, the X moving assembly 210 includes an X power assembly 211 and an X slider support plate 212, the X power assembly 211 is arranged on the Y slider 221, the X slider support plate 212 is connected to the Y slider 221, and the carrier device 300 is movably connected to the X slider support plate 212 and is transmission-connected to the X power assembly 211.

[0056] Specific combination Figure 2 and Figure 5 As shown, when the Y slide plate 221 moves along the Y direction, the Y slide plate 221 drives the X slider support plate 212 and the carrier device 300 to move in the Y direction, and at the same time, the carrier device 300 moves relative to the Y slide plate 221 and the X slider support plate 212 along the X direction, so that the relative position of the carrier device 300 and the frame 100 in the Y direction and the X direction is finally changed, and the X power assembly 211 provides a driving force for the carrier device 300 to move relative to the Y slide plate 221 and the X slider support plate 212 along the X direction.

[0057] Specifically, the carrier device 300 includes a carrier body 310, and a rack 311 and an X slide rail 312 extending along the X direction are arranged on the end surface of the carrier body 310 close to the X slider support plate 212. The X power assembly 211 includes an X driving member 2111 and a gear; the carrier body 310 is slidably connected to the X slider support plate 212 through the X slide rail 312, and the gear is connected to the output shaft of the X driving member 2111 and meshes with the rack 311. Along the Y direction, a plurality of X slide rails 312 are arranged at intervals on the end surface of the carrier body 310 close to the X slider support plate 212. The plurality of X slide rails 312 are all slidably matched with the X slider support plate 212. During the position adjustment process, the plurality of X slide rails 312 play a guiding role, guiding the carrier body 310 to slide relative to the X slider support plate 212 in the X direction; after the position adjustment is completed, the plurality of X slide rails 312 play a limiting role, preventing the carrier body 310 from being separated from the X slider support plate 212 in the Y direction.

[0058] The specific structure of the X moving assembly 210 is as follows: the X moving assembly 210 includes an X driving member 2111, an X connecting rod and two X pulleys 2112, the X driving member 2111 is arranged on the Y slide 221, the two X pulleys 2112 are arranged on the Y slide 221 at intervals, an X pulley 2112 is connected to the output shaft of the X driving member 2111, another X pulley 2112 is sleeved on the first end of the X connecting rod, the two X pulleys 2112 are connected by an X belt transmission, the second end of the X connecting rod passes through the Y slide 221 and the X slider support plate 212, the gear is connected to the second end of the X connecting rod, and the gear is meshed with the rack 311. When adjusting the position, the X driving member 2111 is started, and the gear is driven to rotate through the X pulley 2112, the X belt and the X connecting rod. As the gear rotates, the meshing position with the rack 311 is changed, thereby realizing the relative movement of the carrier body 310 in the X direction. Through the two X pulleys 2112 and the X belt transmission, the X pulley 2112 is arranged in a manner of X connecting rod and gear transmission to achieve the relative movement of the carrier body 310 in the X direction while reducing the space volume of the X moving component 210.

[0059] In some other embodiments, the X pulley 2112, X belt and X connecting rod may not be provided, and the output shaft of the X driving member 2111 may be directly connected to the gear transmission, thereby reducing the use of parts and components and lowering production costs.

[0060] The carrier device 300 also includes an adjustment mechanism. A first opening 313 for placing the gun tip box 20 is provided on the carrier body 310. The adjustment mechanism is connected to the carrier body 310 and is located on one side of the first opening 313. The adjustment mechanism cooperates with the first opening 313 to limit the relative position of the gun tip box 20.

[0061] Specific combination Figure 7 As shown, since an adjustment limit piece 320 is provided on one side of the first opening 313, after the gun tip box 20 is placed in the first opening 313, the adjustment limit piece 320 abuts against the gun tip box 20, which can limit the relative position of the gun tip box 20 and the first opening 313, thereby preventing the gun tip box 20 from moving with the pipette or the gun tip box 20 from being separated from the first opening 313 during the process of replacing the gun tip and moving the pipette out of the gun tip box 20, thereby improving the convenience of replacing the gun tip.

[0062] When limiting the position of the gun tip box 20 placed in the first opening 313, the adjustment limiter 320 can be set only on one side of the first opening 313, so that the gun tip box 20 and the adjustment limiter 320 are interference-fitted; or an elastic clamping assembly 330 can be set on the adjustment limiter 320, so that the adjustment limiter 320 and the elastic clamping assembly 330 cooperate to achieve the elastic clamping assembly 330 and the gun tip box 20 abutting, thereby limiting the relative position of the gun tip box 20, and at the same time, facilitating the disassembly and maintenance of the gun tip box 20 after the pipetting is completed. In this embodiment, the elastic clamping assembly 330 is set on the adjustment limiter 320, and the elastic clamping assembly 330 abuts against the gun tip box 20.

[0063] Preferably, a plurality of adjustment stoppers 320 are provided, and the side walls of the gun head box 20 corresponding to the plurality of adjustment stoppers 320 can be detachably connected to the carrier body 310. The number of adjustment stoppers 320 corresponding to the side walls of the gun head box 20 can be set to two, three or four, and the specific number of settings can be appropriately increased or decreased according to actual needs. In this embodiment, two adjustment stoppers 320 are provided, and the two adjustment stoppers 320 are connected to one side of the first opening 313 corresponding to the two opposite side walls of the gun head box 20, and the two adjustment stoppers 320 are both provided with elastic clamping components 330, such as Figure 7 Such a configuration can better limit the relative position of the gun tip box 20 in the first opening 313 from two directions, further improving the convenience of replacing the gun tip.

[0064] In some other embodiments, the elastic clamping assembly 330 may be provided on only one of the adjustment and limiting members 320 , and the other adjustment and limiting members 320 directly abut against the side wall of the gun tip box 20 .

[0065] Preferably, the elastic snap-fit ​​assembly 330 includes an elastic member 331 and an abutment member 332, the first end of the elastic member 331 is fixedly connected to the adjustment limit member 320, and the second end extends toward the middle of the first opening 313, the abutment member 332 is connected to the second end of the elastic member 331, and abuts against the gun tip box 20.

[0066] Specific combination Figure 8The cam 332 is in the state of being moved to the left of the cam 333, so that the cam 333 is in the state of being moved to the right of the cam 333. The cam 332 is in the state of being moved to the left of the cam 333, so that the cam 333 is in the state of being moved to the right of the cam 333.

[0067] In order to further improve the convenience of placing the gun tip box 20 in the first opening 313, or removing the gun tip box 20 from the first opening 313, the abutment 332 can be set to a columnar shape, and the end surface of the abutment 332 facing away from the elastic member 331 can be set as a guide surface, or the abutment 332 can be directly set to a sphere, thereby further improving the convenience of replacing the gun tip.

[0068] Preferably, the elastic clamping assembly 330 further includes a guide groove 333, which is arranged on the first side wall 321 of the adjustment limiter 320, and the first end of the elastic member 331 is fixedly connected to the bottom wall of the guide groove 333. The length of the compression spring is greater than or equal to the depth of the guide groove 333; during the disassembly and assembly of the gun tip box 20, the compression spring is compressed, and the abutment member 332 is compressed into the guide groove 333 to facilitate the disassembly and assembly of the gun tip box 20; after the gun tip box 20 is placed in the first opening 313, the compression spring automatically retracts, and the abutment member 332 extends to the open end of the guide groove 333 and abuts against the corresponding side wall of the gun tip box 20 to limit the relative position of the gun tip box 20. During the compression or autonomous retraction of the compression spring, the guide groove 333 guides and limits the compression spring, guides the compression spring to move along a predetermined path, and avoids bending and tilting during the movement of the compression spring, thereby further ensuring the limiting effect of the gun tip box 20.

[0069] In some other embodiments, the elastic clamping assembly 330 further includes an auxiliary member 334, an auxiliary channel is provided on the guide groove 333, the auxiliary member 334 is connected to the elastic member 331 or the abutting member 332, and extends out of the adjustment limit member 320 through the auxiliary channel. Specifically, at least one of the abutting members 332 is connected to the auxiliary member 334, and the auxiliary channel is provided on the guide groove 333 corresponding to the abutting member 332; when the gun tip box 20 needs to be removed, the auxiliary member 334 is pulled to move in a direction away from the gun tip box 20, so that the elastic member 331 is compressed, so that a gap appears between the gun tip box 20 and the other adjustment limit member 320, thereby facilitating the removal of the gun tip box 20.

[0070] In order to further improve the limiting effect of the gun tip box 20, a plurality of elastic clamping components 330 are arranged at intervals on the adjusting and limiting member 320. In this embodiment, two elastic clamping components 330 are arranged at intervals on one adjusting and limiting member 320.

[0071] Preferably, a plurality of second openings 314 for accommodating the carrier 30 are disposed at intervals on the carrier body 310 .

[0072] Combination Figure 7 As shown, the number of carriers 30 is appropriately increased or decreased according to actual needs, and the number of second openings 314 corresponds to the number of carriers 30, which can achieve the technical effect of storing source liquid or contaminated liquid and improving the overall convenience of use of the pipetting workstation. In this embodiment, three second openings 314 are spaced apart on the carrier body 310, and three corresponding carriers 30 are also provided.

[0073] Obviously, the above embodiments of the present invention are merely examples for the purpose of clearly illustrating the present invention, and are not intended to limit the implementation methods of the present invention. For those skilled in the art, various obvious changes, readjustments and substitutions can be made without departing from the scope of protection of the present invention. It is not necessary and impossible to list all implementation methods here. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention shall be included in the scope of protection of the claims of the present invention.

Claims

1. A pipetting workstation, characterized in that: include: Multi-tip pipette assembly (10); Rack(100); A liquid transfer device, comprising an X-moving assembly (210), a Y-moving assembly (220) and a Z-moving assembly (230), wherein the Z-moving assembly (230) is fixedly connected to the frame (100), the multi-gun tip liquid transfer device assembly (10) is transmission-connected to the Z-moving assembly (230), the Z-moving assembly (230) drives the multi-gun tip liquid transfer device assembly (10) to move up and down along the Z direction, the Y-moving assembly (220) comprises a Y-slide plate (221) and a Y-power assembly (222), the X-moving assembly (210) is connected to the Y-slide plate (221), the Y-slide plate (221) is movably connected to the frame (100), and the Y-power assembly (222) is transmission-connected to the Y-slide plate (221) to drive the Y-slide plate (221) to move along the Y direction; The carrier device (300) is connected to the X-moving assembly (210) and is used to place the gun tip box (20) and the carrier (30) to cooperate with the multi-gun tip pipette assembly (10) to complete gun tip replacement or pipetting.

2. The liquid handling workstation according to claim 1, characterized in that: The Y moving assembly (220) further includes a Y slide rail (223), and the Y power assembly (222) includes a Y driving member (2221) and a fixing frame (2222); One of the Y driving member (2221) and the fixed frame (2222) is connected to the frame (100), and the other is connected to the Y slide plate (221); the output shaft of the Y driving member (2221) is transmission-connected to the fixed frame (2222); the Y slide rail (223) is fixedly arranged on the frame (100) and extends along the Y direction; the Y slide plate (221) is slidably connected to the Y slide rail (223).

3. The liquid handling workstation according to claim 2, characterized in that: The Y moving component (220) further comprises a position sensor (224) and a controller. The position sensor (224) is arranged on one side of the Y sliding plate (221) and is used to sense the position of the Y sliding plate (221). Both the position sensor (224) and the Y driving member (2221) are connected to the controller.

4. The liquid handling workstation according to claim 3, characterized in that: The Y moving component (220) further comprises an auxiliary sensing component (225), one end of which is fixedly connected to the Y sliding plate (221), and the position sensor (224) is inductively matched with the other end of the auxiliary sensing component (225), and the position sensor (224) senses the position of the auxiliary sensing component (225) and sends a signal to the controller.

5. The liquid handling workstation according to claim 1, characterized in that: The Y moving assembly (220) further comprises two supporting pallets (226), the two supporting pallets (226) are both fixedly connected to the frame (100), and are fixedly arranged at intervals on both sides of the Y sliding plate (221) along the X direction, and the Z moving assembly (230) is fixedly connected to the two supporting pallets (226).

6. The liquid handling workstation according to any one of claims 1 to 5, characterized in that: The X moving assembly (210) comprises an X power assembly (211) and an X slider support plate (212); the X power assembly (211) is arranged on the Y slider (221); the X slider support plate (212) is connected to the Y slider (221); the carrier device (300) is movably connected to the X slider support plate (212) along the X direction and is transmission-connected to the X power assembly (211).

7. The liquid handling workstation according to claim 6, characterized in that: The carrier device (300) comprises a carrier body (310), a rack (311) and an X slide rail (312) extending in the X direction are arranged on the end surface of the carrier body (310) close to the X slide support plate (212), and the X power assembly (211) comprises an X driving member (2111) and a gear; The carrier body (310) is slidably connected to the X-slider support plate (212) via the X-slide rail (312); the gear transmission is connected to the output shaft of the X-driving member (2111) and meshes with the rack (311).

8. The liquid handling workstation according to claim 7, characterized in that: The carrier device (300) further comprises an adjusting mechanism, a first opening (313) for placing a gun tip box (20) is provided on the carrier body (310), the adjusting mechanism is connected to the carrier body (310) and is located on at least one side of the first opening (313), and the adjusting mechanism cooperates with the first opening (313) to limit the relative position of the gun tip box (20).

9. The liquid handling workstation according to claim 8, characterized in that: The adjustment mechanism comprises an adjustment limiter (320) and an elastic clamping assembly (330), wherein the adjustment limiter (320) is arranged on one side of the first opening (313), and the elastic clamping assembly (330) is arranged on the adjustment limiter (320) and abuts against the gun tip box (20).

10. The liquid handling workstation according to claim 9, characterized in that: The elastic clamping assembly (330) comprises an elastic member (331) and an abutment member (332); a guide groove (333) is provided on the adjustment limit member (320); a first end of the elastic member (331) is connected to the bottom wall of the guide groove (333); and the abutment member (332) is connected to the second end of the elastic member (331) and abuts against the gun tip box (20).

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