Bioreactor for producing bacteriostatic agent

By introducing side scrapers and lower scrapers into the bioreactor, combining heating plates and temperature sensors, the problem of reactants is solved, the processing capacity and output quality of the reactor are improved, and a suitable microbial culture environment is achieved.

CN222226331UActive Publication Date: 2024-12-24金博大生物医药科技(武汉)有限公司
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Patent Information

Application Number
CN202420884371.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-26
Publication Date
2024-12-24
Estimated Expiration
2034-04-26

AI Technical Summary

Technical Problem

When used in existing bioreactors, reactants are prone to adhere or accumulate on the inner wall and bottom end of the reaction vessel, resulting in some reactants being unable to be effectively utilized, affecting the reactor's processing capacity and output quality.

Method used

A bioreactor for the production of antibacterial agents is designed, including a reaction tank, heating chamber, side scraper and lower scraper. The reactants are scraped by rotating the connecting rod to drive the stirring leaves and scraper, combining the heating plate and temperature. The sensor realizes a constant temperature environment, improving reactant utilization and microbial yield.

Benefits of technology

Through the design of side scrapers and lower scrapers, the utilization rate of reactants is improved, the processing capacity and output quality of the reactor are ensured, and the yield and quality of microorganisms are improved through a constant temperature environment.

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Abstract

The utility model discloses a bioreactor for bacteriostatic agent production, and relates to the technical field of bacteriostatic agent production, the bioreactor comprises a reaction tank and a heating cavity arranged in the side wall of the reaction tank, the lower end of the reaction tank is funnel-shaped, and the top end of the inner side of the reaction tank is rotatably connected with a rotating shaft; the outer surface of the rotating shaft is fixedly connected with a plurality of uniformly distributed connecting rods, the end parts of the connecting rods are fixedly connected with side scrapers tightly attached to the inner side wall of the reaction tank, the lower ends of the side scrapers are fixedly connected with obliquely arranged lower scrapers, and the lower scrapers are tightly attached to the bottom end of the inner side of the reaction tank; a plurality of stirring blades arranged at equal intervals are fixedly connected to the outer surface of the connecting rod, a motor used for driving a rotating shaft to rotate is fixedly installed at the center of the upper end of the reaction tank, a plurality of heating plates are fixedly connected to the interior of a heating cavity, and reactants attached to the inner wall of the reaction tank are scraped by arranging side scraping plates and a lower scraping plate; the utilization rate of reactants and the output quality of the reactor are improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of antibacterial agent production, in particular to a bioreactor for antibacterial agent production. Background Art

[0002] Bacteriostatics are substances that inhibit the growth of bacteria. Bacteriostatics may not kill bacteria, but they can inhibit their growth and prevent them from overgrowing and endangering health. In the production process of bacteriostatics, microbial culture and reaction are required to obtain efficient production and quality.

[0003] When existing bioreactors are in use, reactants tend to adhere to or accumulate on the inner wall and bottom of the reaction vessel, resulting in some reactants being unable to be effectively utilized, thereby affecting the processing capacity and output quality of the reactor. Utility Model Content

[0004] In order to solve the above technical problems, a bioreactor for the production of antibacterial agents is provided. The technical solution solves the problem that when the existing bioreactor proposed in the above background technology is in use, the reactants are easily attached or accumulated on the inner wall and bottom of the reaction container, resulting in some reactants cannot be effectively utilized, thereby affecting the processing capacity and output quality of the reactor.

[0005] In order to achieve the above purpose, the technical solution adopted by the utility model is:

[0006] A bioreactor for producing an antibacterial agent comprises a reaction tank and a heating chamber opened in the side wall of the reaction tank, wherein the lower end of the reaction tank is funnel-shaped, the inner top end of the reaction tank is rotatably connected to a rotating shaft, the outer surface of the rotating shaft is fixedly connected to a plurality of evenly distributed connecting rods, the ends of the connecting rods are fixedly connected to side scrapers that fit tightly with the inner wall of the reaction tank, the lower ends of the side scrapers are fixedly connected to inclined lower scrapers that fit tightly with the inner bottom end of the reaction tank, the outer surface of the connecting rods are fixedly connected to a plurality of stirring blades that are arranged at equal intervals, a motor for driving the rotating shaft to rotate is fixedly installed at the center of the upper end of the reaction tank, and a plurality of heating plates are fixedly connected to the inside of the heating chamber.

[0007] Preferably, a temperature sensor is provided at the right portion of the upper end of the reaction tank, and a measuring end of the temperature sensor passes through the upper end of the reaction tank and extends into the interior of the reaction tank.

[0008] Preferably, a feed pipe communicating with the interior of the reaction tank is fixedly connected to the left upper end of the reaction tank, and a dust cover is threadedly connected to the upper end of the feed pipe.

[0009] Preferably, an air inlet hole is formed through the lower end of the reaction tank, a gas pipe is fixedly connected to the inside of the air inlet hole, and a gas tank is fixedly connected to the other end of the gas pipe.

[0010] Preferably, a discharge pipe is fixedly connected to the lower end of the reaction tank, and a valve is provided on the discharge pipe.

[0011] Preferably, a base for supporting and fixing the reaction tank is fixedly connected to the lower edge of the reaction tank.

[0012] Preferably, a controller is provided on the outer surface of the reaction tank.

[0013] Compared with the prior art, the utility model has the following beneficial effects:

[0014] This scheme proposes a bioreactor for the production of antibacterial agents. By setting side scrapers and lower scrapers to scrape off the reactants attached to the inner wall of the reaction tank, the utilization rate of the reactants is improved, thereby improving the processing capacity and output quality of the reactor.

[0015] In this solution, a heating plate is provided to heat the inner wall of the reaction tank through the heating plate and the temperature inside the tank is monitored in real time using a temperature sensor. The data of the temperature sensor will be synchronously transmitted to the controller, and the controller will adjust the heating effect of the heating plate according to the preset temperature, so that the reaction tank is in a constant temperature environment suitable for microbial cultivation, which can improve the yield and quality of microorganisms. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a structural schematic diagram of the utility model;

[0017] Figure 2 It is a schematic diagram of the structure inside the reaction tank in the utility model;

[0018] Figure 3 It is a structural schematic diagram of the heating chamber in the utility model.

[0019] The numbers in the figure are:

[0020] 1. Base; 2. Reactor; 3. Rotating shaft; 4. Connecting rod; 5. Side scraper; 6. Stirring blade; 7. Lower scraper; 8. Heating chamber; 9. Heating plate; 10. Temperature sensor; 11. Feed pipe; 12. Dust cover; 13. Motor; 14. Air inlet; 15. Air pipe; 16. Air tank; 17. Discharge pipe; 18. Valve; 19. Controller. DETAILED DESCRIPTION

[0021] The following description is used to disclose the present invention so that those skilled in the art can implement the present invention. The preferred embodiments described below are only examples, and those skilled in the art may think of other obvious variations.

[0022] Reference Figure 2 and Figure 3As shown, a bioreactor for the production of an antibacterial agent comprises a reaction tank 2 and a heating chamber 8 opened in the side wall of the reaction tank 2. The lower end of the reaction tank 2 is funnel-shaped to facilitate the discharge of the product. The inner top end of the reaction tank 2 is rotatably connected with a rotating shaft 3. The outer surface of the rotating shaft 3 is fixedly connected with a plurality of evenly distributed connecting rods 4. The end of the connecting rod 4 is fixedly connected with a side scraper 5 that is tightly fitted with the inner wall of the reaction tank 2. The lower end of the side scraper 5 is fixedly connected with an inclined lower scraper 7. The lower scraper 7 is tightly fitted with the inner bottom end of the reaction tank 2. The side scraper 5 and the lower scraper 7 can scrape off the reactants attached to the inner wall of the reaction tank 2, thereby improving the utilization rate of the reactants. The outer surface of the connecting rod 4 is fixedly connected with a plurality of stirring blades 6 that are arranged at equal intervals. A motor 13 for driving the rotating shaft 3 to rotate is fixedly installed at the center of the upper end of the reaction tank 2. The rotating shaft 3 is driven to rotate by the motor 13, and then the stirring blades 6 are driven to stir the reactants, so that the microorganisms and the reactants are fully in contact. The interior of the heating chamber 8 is fixedly connected with a plurality of heating plates 9.

[0023] Reference Figure 1 and Figure 2 As shown, a temperature sensor 10 is provided at the right upper end of the reaction tank 2. The temperature sensor 10 may adopt a temperature sensor with a model number of RTD04-1125-3N. The measuring end of the temperature sensor 10 passes through the upper end of the reaction tank 2 and extends to the inside of the reaction tank 2. A controller 19 is provided on the outer surface of the reaction tank 2. The controller 19 may adopt a controller with a model number of XMT5-8011K02. The inner wall of the reaction tank 2 is heated by the heating plate 9 and the temperature inside the reaction tank 2 is monitored in real time by the temperature sensor 10. The measurement data of the temperature sensor 10 will be synchronously transmitted to the controller 19. The controller 19 will adjust the heating effect of the heating plate 9 according to the preset temperature, so that the reaction tank 2 is in a constant temperature environment suitable for microbial culture.

[0024] Furthermore, a feed pipe 11 connected to the interior of the reaction tank 2 is fixedly connected to the left upper end of the reaction tank 2, and a dust cover 12 is threadedly connected to the upper end of the feed pipe 11. The dust cover 12 can be isolated after the reactants are added to prevent other bacteria from entering the interior of the reaction tank 2 and affecting the purity of the product.

[0025] An air inlet 14 is formed at the lower end of the reaction tank 2, and a gas pipe 15 is fixedly connected to the inside of the air inlet 14. A gas tank 16 is fixedly connected to the other end of the gas pipe 15. The gas tank 16 is used to store gas or oxygen required for the reaction and to adjust the gas concentration inside the reaction tank 2.

[0026] A discharge pipe 17 is fixedly connected to the lower end of the reaction tank 2 , and a valve 18 is provided on the discharge pipe 17 .

[0027] A base 1 for supporting and fixing the reaction tank 2 is fixedly connected to the lower edge of the reaction tank 2 .

[0028] Working principle: When the device is in use, the dust cover 12 is turned to open, and raw materials such as active ingredients, solvents, additives and preservatives are added into the reaction tank 2 through the feed pipe 11, and then the dust cover 12 is covered, and the motor 13 drives the rotating shaft 3 to rotate, so that the connecting rod 4 drives the stirring blade 6 to fully stir the reactants. At the same time, the side scraper 5 and the lower scraper 7 on the outside of the connecting rod 4 can scrape off the reactants attached to the inner wall of the reaction tank 2 to improve the utilization rate of the reactants. During the reaction, the reaction tank 2 is heated by the heating plate 9, and the temperature sensor 10 and the controller 19 are used to monitor and adjust the temperature of the reaction tank 2 in real time, so that the reaction tank 2 is in a constant temperature environment suitable for microbial cultivation. The gas required for the reaction can be introduced into the reaction tank 2 through the gas tank 16 and the gas pipe 15, and the gas concentration can be adjusted through the control valve of the gas tank 16. After the reaction is completed, the valve 18 is opened to discharge the reactants.

[0029] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and the specification only describe the principles of the utility model. The utility model may be subject to various changes and improvements without departing from the spirit and scope of the utility model. These changes and improvements fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.

Claims

1. A bioreactor for producing an antibacterial agent, characterized in that: The invention comprises a reaction tank (2) and a heating chamber (8) opened in the side wall of the reaction tank (2); the lower end of the reaction tank (2) is funnel-shaped; the inner top end of the reaction tank (2) is rotatably connected to a rotating shaft (3); the outer surface of the rotating shaft (3) is fixedly connected to a plurality of evenly distributed connecting rods (4); the end of the connecting rod (4) is fixedly connected to a side scraper (5) tightly fitted with the inner wall of the reaction tank (2); the lower end of the side scraper (5) is fixedly connected to an inclined lower scraper (7); the lower scraper (7) is tightly fitted with the inner bottom end of the reaction tank (2); the outer surface of the connecting rod (4) is fixedly connected to a plurality of stirring blades (6) arranged at equal intervals; a motor (13) for driving the rotating shaft (3) to rotate is fixedly installed at the center of the upper end of the reaction tank (2); and the interior of the heating chamber (8) is fixedly connected to a plurality of heating plates (9).

2. A bioreactor for producing an antibacterial agent according to claim 1, characterized in that: A temperature sensor (10) is provided at the right portion of the upper end of the reaction tank (2), and a measuring end of the temperature sensor (10) passes through the upper end of the reaction tank (2) and extends into the interior of the reaction tank (2).

3. A bioreactor for producing an antibacterial agent according to claim 1, characterized in that: A feed pipe (11) communicating with the interior of the reaction tank (2) is fixedly connected to the left upper end of the reaction tank (2), and a dust cover (12) is threadedly connected to the upper end of the feed pipe (11).

4. A bioreactor for producing an antibacterial agent according to claim 1, characterized in that: An air inlet (14) is provided through the lower end of the reaction tank (2), a gas supply pipe (15) is fixedly connected to the inside of the air inlet (14), and a gas tank (16) is fixedly connected to the other end of the gas supply pipe (15).

5. A bioreactor for producing an antibacterial agent according to claim 1, characterized in that: The lower end of the reaction tank (2) is fixedly connected with a discharge pipe (17), and a valve (18) is provided on the discharge pipe (17).

6. A bioreactor for producing an antibacterial agent according to claim 1, characterized in that: A base (1) for supporting and fixing the reaction tank (2) is fixedly connected to the lower edge of the reaction tank (2).

7. A bioreactor for producing an antibacterial agent according to claim 1, characterized in that: A controller (19) is provided on the outer surface of the reaction tank (2).