Stem cell purification device

Abstract

The utility model discloses a stem cell purification device, which relates to the technical field of purification devices and comprises a purification device body, and cooling fans are arranged in two sides of the purification device body. An air inlet cover is fixedly installed on the two sides of the purification device body and located on one side of the cooling fan, semiconductor chilling plates are arranged on the top and the bottom of the air inlet cover, a plurality of temperature conduction copper plates are fixedly installed on the refrigeration faces of the semiconductor chilling plates and located on the inner side of the air inlet cover, and the cooling fan is matched with the temperature conduction copper plates; the stem cell purification device has the beneficial effects that refrigeration can be performed through the semiconductor refrigeration sheet in the purification process, then the temperature of the temperature conducting copper plate is reduced, and when the cooling fan is started to blow air into the purification device body, external air exchanges heat with the temperature conducting copper plate so as to play a role in cooling, so that the temperature of purified stem cells is reduced, and the purification effect is improved. The activity and survival rate of the stem cells are improved, and purification of the adipose-derived stem cells is facilitated.

Description

Technical Field

[0001] The utility model relates to the technical field of purification devices, in particular to a stem cell purification device. Background Art

[0002] Adipose stem cells are a type of stem cell with multidirectional differentiation potential isolated from adipose tissue. They mainly restore the repair function of tissue cells and promote cell regeneration. They are expected to become a source of stem cells for repairing damaged tissues and organs. They are currently also widely used to restore breast shape after breast cancer surgery, and provide an important basis for the ultimate successful repair and functional reconstruction of the breast.

[0003] According to a fat stem cell purification device with application number 202121907434.1, a stirring plate, a stirring cover, a stirring column and a motor are provided, and a slider slides inside a corresponding slide groove, and the motor is started, and the motor output shaft drives the rotating column and the stirring plate to rotate. Since the stirring rod installed at the bottom of the stirring column fits the inner wall of the culture dish, after the extracted fat is placed inside the culture dish, the rotating column is rotated so that the stirring rod stirs and breaks the fat. Through this structure, the fat inside can be effectively stirred and decomposed into fat tissue blocks, which saves the time of staff in stirring and decomposing tissue blocks, solves the problem that uneven stirring affects the quality of stem cell extraction from tissue blocks, and improves the working efficiency of the purification device.

[0004] However, the above-mentioned stem cell purification device has certain shortcomings. The stem cells need to be purified at a lower temperature. The device needs to stir the fat during the purification process. During stirring, the stirring rod will convert mechanical energy into friction heat and kinetic energy inside the fat, causing the temperature of the purified fat to increase, thereby reducing the activity and survival rate of the stem cells, which is not convenient for stem cell purification. In addition, the stirring structure of the purification device has certain defects. During stirring, the stirring plate and the stirring rod need to be driven by a motor to rotate to achieve the stirring effect. However, when the stirring plate rotates, the stirring rod will rotate with the stirring plate, and cannot effectively stir the tissue blocks in the culture dish. For this reason, we propose a stem cell purification device. Utility Model Content

[0005] In view of the deficiencies of the prior art, the utility model provides a stem cell purification device, which solves the problems raised in the above background technology.

[0006] To achieve the above objectives, the utility model is implemented through the following technical solutions: a stem cell purification device, including a purification device body, cooling fans are arranged inside both sides of the purification device body, air inlet covers are fixedly installed on both sides of the purification device body and on one side of the cooling fan, semiconductor refrigeration plates are arranged on the top and bottom of the air inlet cover, a plurality of temperature-conducting copper plates are fixedly installed on the cooling surface of the semiconductor refrigeration plates and on the inner side of the air inlet cover, the cooling fan cooperates with the temperature-conducting copper plates, exhaust ports are opened inside the purification device body and on the top and bottom of the cooling fan, heat dissipation fins are fixedly installed on the heat dissipation surface of the semiconductor refrigeration plates, and the exhaust ports cooperate with the heat dissipation fins.

[0007] Preferably, a motor is fixedly installed at the bottom of the interior of the purification device body, a mounting frame is fixedly installed at the output end of the motor, a plurality of fixing holes are opened inside the mounting frame, a purification test tube is arranged inside the fixing holes, the cooling fan cooperates with the purification test tube, a connecting column is fixedly installed in the middle of the top of the mounting frame, a mounting plate is arranged on the outer side of the connecting column, a through hole is opened in the middle of the mounting plate, the through hole cooperates with the connecting column, a clamping mechanism is arranged inside the connecting column, a plurality of stirring rods are rotatably installed inside the mounting plate, the stirring rod cooperates with the purification test tube, a gear is fixedly installed on one end of the stirring rod, an inner gear ring is fixedly installed on the inner wall of the purification device body, and the gear is meshed with the inner gear ring.

[0008] Preferably, the clamping mechanism includes a reset groove, two reset grooves are provided inside the connecting column, a slide is movably installed inside the reset groove, a clamping block is fixedly installed on one side of the slide, clamping grooves are provided inside the mounting plate and on both sides of the through hole, the clamping block cooperates with the clamping grooves, a spring is installed inside the reset groove and on one side of the slide, the slide cooperates with the spring, a pull groove is provided inside the connecting column and above the reset groove, a pull plate is fixedly installed on the top of the slide, and the pull plate is slidably connected to the pull groove.

[0009] Preferably, a bearing cooperating with the stirring rod is arranged inside the mounting plate.

[0010] Preferably, two grooves are formed inside the mounting plate.

[0011] Preferably, a box cover is provided on the top of the purification device body, a control panel is provided on the outside of the purification device body, and a temperature sensor is provided on the inner wall of the purification device body.

[0012] The utility model provides a stem cell purification device, which has the following beneficial effects:

[0013] 1. The stem cell purification device cooperates with a cooling fan, an air inlet hood, a semiconductor refrigeration sheet, a thermal copper plate, an exhaust port and heat dissipation fins. During the purification process, the semiconductor refrigeration sheet can be used for cooling, and then the temperature of the thermal copper plate is reduced. When the cooling fan is turned on to blow air into the purification device body, the outside air will exchange heat with the thermal copper plate to achieve a cooling effect, thereby reducing the temperature of the purified stem cells, improving the activity and survival rate of the stem cells, and being more conducive to the purification of adipose stem cells.

[0014] 2. The stem cell purification device cooperates with a motor, a mounting frame, a purification test tube, a connecting column, a mounting plate, a stirring rod, gears and an inner gear ring. During the purification process, the mounting frame, the purification test tube and the mounting plate can be driven to rotate by turning on the motor. When the mounting plate rotates, the gear engages with the inner gear ring and then drives the stirring rod to rotate to stir the fat in the purification test tube. Compared with the existing technology, the stirring effect and purification efficiency of the stem cells are effectively improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the structure of the utility model;

[0016] Figure 2 It is a cross-sectional view of the utility model;

[0017] Figure 3 It is a top view of the utility model;

[0018] Figure 4 For this utility model Figure 2 A in the enlarged view;

[0019] Figure 5 For this utility model Figure 2 Enlarged view of point B in .

[0020] In the figure: 1. purification device body; 2. cooling fan; 3. air inlet hood; 4. semiconductor refrigeration plate; 5. thermal conductive copper plate; 6. spring; 7. exhaust port; 8. heat dissipation fin; 9. motor; 10. mounting frame; 11. fixing hole; 12. purification test tube; 13. connecting column; 14. mounting plate; 15. through hole; 16. reset groove; 17. slide plate; 18. block; 19. slot; 20. pull groove; 21. pull plate; 22. stirring rod; 24. gear; 25. inner gear ring. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0022] See also Figures 1 to 5The utility model provides a technical solution: a stem cell purification device, including a purification device body 1, a box cover is arranged on the top of the purification device body 1, a control panel is arranged on the outside of the purification device body 1, and a temperature sensor is arranged on the inner wall of the purification device body 1. The main function of the temperature sensor is to monitor the stability inside the purification device body 1, so that the staff can timely understand whether the temperature inside the purification device body 1 is conducive to stem cell purification, wherein the cooling fan 2, the semiconductor refrigeration sheet 4, the motor 9 and the temperature sensor are all electrically connected to the control panel.

[0023] Cooling fans 2 are provided inside both sides of the purification device body 1, and air inlet hoods 3 are fixedly installed on both sides of the purification device body 1 and on one side of the cooling fan 2. Semiconductor refrigeration plates 4 are provided on the top and bottom of the air inlet hood 3. Several heat-conducting copper plates 5 are fixedly installed on the cooling surface of the semiconductor refrigeration plate 4 and on the inner side of the air inlet hood 3. The cooling fan 2 cooperates with the heat-conducting copper plates 5. Exhaust ports 7 are provided inside the purification device body 1 and on the top and bottom of the cooling fan 2. Heat dissipation fins 8 are fixedly installed on the heat dissipation surface of the semiconductor refrigeration plate 4. The exhaust ports 7 cooperate with the heat dissipation fins 8. The main function of the exhaust ports 7 is to discharge the air in the purification device body 1 when the cooling fan 2 blows air into the purification device body 1, and take away the heat on the heat dissipation fins 8 while discharging, thereby improving the heat dissipation efficiency of the heat dissipation fins 8 to the semiconductor refrigeration plate 4.

[0024] A motor 9 is fixedly installed at the bottom of the purification device body 1, and a mounting frame 10 is fixedly installed at the output end of the motor 9. A plurality of fixing holes 11 are opened inside the mounting frame 10, and a purification test tube 12 is arranged inside the fixing hole 11. The cooling fan 2 cooperates with the purification test tube 12, wherein a fixing groove cooperating with the purification test tube 12 is opened inside the bottom of the mounting frame 10, wherein a rubber clamping ring is arranged inside the fixing hole 11, and its main function is to fix the purification test tube 12 inside the fixing hole 11, and also to avoid the purification test tube 12 idling during purification and stirring. A connecting column 13 is fixedly installed in the middle of the top of the mounting frame 10, and a mounting plate 14 is arranged on the outside of the connecting column 13, and two grooves are arranged inside the mounting plate 14, which The main function of the two middle grooves is to facilitate the taking and installation of the mounting plate 14. A through hole 15 is opened in the middle of the mounting plate 14, and the through hole 15 cooperates with the connecting column 13. The connecting column 13 is rectangular, and a clamping mechanism is arranged inside the connecting column 13. Several stirring rods 22 are rotatably installed inside the mounting plate 14. The interior of the mounting plate 14 is provided with bearings that cooperate with the stirring rods 22. The main function of the bearings is to improve the smoothness of the rotation of the stirring rod 22 to avoid the stirring rod 22 from getting stuck when the gear 24 is meshed with the inner gear ring 25. The stirring rod 22 cooperates with the purification test tube 12, and a gear 24 is fixedly installed on one end of the stirring rod 22. An inner gear ring 25 is fixedly installed on the inner wall of the purification device body 1, and the gear 24 is meshed with the inner gear ring 25.

[0025] The clamping mechanism includes a reset groove 16. Two reset grooves 16 are provided inside the connecting column 13. A slide plate 17 is movably installed inside the reset groove 16. A clamping block 18 is fixedly installed on one side of the slide plate 17. A clamping groove 19 is provided inside the mounting plate 14 and on both sides of the through hole 15. The clamping block 18 cooperates with the clamping groove 19. A spring 6 is installed inside the reset groove 16 and on one side of the slide plate 17. The slide plate 17 cooperates with the spring 6. A pull groove 20 is provided inside the connecting column 13 and above the reset groove 16. A pull plate 21 is fixedly installed on the top of the slide plate 17. The pull plate 21 is slidably connected to the pull groove 20. The main function of the clamping mechanism is to facilitate the installation and disassembly of the mounting plate 14 on the outside of the connecting column 13, so as to facilitate the placement of the purification test tube 12 into the fixing hole 11 during purification and the removal of the purification test tube 12 after purification.

[0026] In summary, when the stem cell purification device is used, the box cover is first opened, and then the two pull plates 21 are pulled to drive the slide plate 17 and the block 18 to move. After the block 18 is pulled out of the slot 19, the mounting plate 14 can be vertically lifted to be removed, and then the purification tube 12 containing adipose tissue is inserted into the fixing hole 11, and then the mounting plate 14 is installed back to the outside of the connecting column 13. During installation, it is necessary to pay attention to inserting the stirring rod 22 into the purification tube 12 and making the gear 24 mesh with the inner gear ring 25. When installing the mounting plate 14, the pull plate 21 is also pulled to move the block 18. When the mounting plate 14 is placed on the outside of the connecting column 13, the pull plate 21 is released to allow the spring 6 to rebound and push the slide plate 17 and the block 18 to reset, thereby The card block 18 is inserted into the card slot 19, and then purification can begin. During purification, the cooling fan 2, the semiconductor refrigeration plate 4 and the motor 9 are turned on at the same time. The motor 9 drives the mounting frame 10 and the mounting plate 14 to rotate. When the mounting plate 14 rotates, the gear 24 engages with the inner gear ring 25 and then drives the stirring rod 22 to rotate to stir and purify the fat tissue in the purification test tube 12. At the same time, when the semiconductor refrigeration plate 4 is turned on, its cooling surface reduces the temperature of the temperature of the heat-conducting copper plate 5. When the cooling fan 2 is turned on, the outside air is blown into the purification device body 1. When the air enters the purification device body 1, it exchanges heat with the heat-conducting copper plate 5, thereby reducing the temperature of the air to cool the purification test tube 12, which is more conducive to the purification of adipose stem cells.

[0027] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A stem cell purification device, comprising a purification device body (1), characterized in that: Cooling fans (2) are provided inside both sides of the purification device body (1), and air inlet covers (3) are fixedly installed on both sides of the purification device body (1) and on one side of the cooling fan (2). Semiconductor cooling plates (4) are provided on the top and bottom of the air inlet cover (3), and a plurality of heat-conducting copper plates (5) are fixedly installed on the cooling surface of the semiconductor cooling plate (4) and on the inner side of the air inlet cover (3). The cooling fan (2) cooperates with the heat-conducting copper plates (5), and exhaust ports (7) are provided inside the purification device body (1) and on the top and bottom of the cooling fan (2). Heat-dissipating fins (8) are fixedly installed on the heat-dissipating surface of the semiconductor cooling plate (4), and the exhaust ports (7) cooperate with the heat-dissipating fins (8).

2. A stem cell purification device according to claim 1, characterized in that: A motor (9) is fixedly installed at the bottom of the purification device body (1), and a mounting frame (10) is fixedly installed at the output end of the motor (9). A plurality of fixing holes (11) are opened inside the mounting frame (10), and a purification test tube (12) is arranged inside the fixing hole (11). The cooling fan (2) cooperates with the purification test tube (12). A connecting column (13) is fixedly installed in the middle of the top of the mounting frame (10), and a mounting plate (14) is arranged on the outer side of the connecting column (13). A through hole (15) is provided in the middle of the plate (14), and the through hole (15) cooperates with the connecting column (13). A clamping mechanism is provided inside the connecting column (13). A plurality of stirring rods (22) are rotatably installed inside the mounting plate (14), and the stirring rods (22) cooperate with the purification test tube (12). A gear (24) is fixedly installed at one end of the stirring rod (22). An inner gear ring (25) is fixedly installed on the inner wall of the purification device body (1), and the gear (24) meshes with the inner gear ring (25).

3. A stem cell purification device according to claim 2, characterized in that: The clamping mechanism comprises a reset groove (16), two reset grooves (16) are provided inside the connecting column (13), a slide plate (17) is movably installed inside the reset groove (16), a clamping block (18) is fixedly installed on one side of the slide plate (17), a clamping groove (19) is provided inside the mounting plate (14) and on both sides of the through hole (15), the clamping block (18) cooperates with the clamping groove (19), a spring (6) is installed inside the reset groove (16) and on one side of the slide plate (17), the slide plate (17) cooperates with the spring (6), a pull groove (20) is provided inside the connecting column (13) and above the reset groove (16), a pull plate (21) is fixedly installed on the top of the slide plate (17), and the pull plate (21) is slidably connected to the pull groove (20).

4. A stem cell purification device according to claim 2, characterized in that: A bearing matched with the stirring rod (22) is arranged inside the mounting plate (14).

5. A stem cell purification device according to claim 2, characterized in that: Two grooves are formed inside the mounting plate (14).

6. A stem cell purification device according to claim 1, characterized in that: A box cover is arranged on the top of the purification device body (1), a control panel is arranged on the outside of the purification device body (1), and a temperature sensor is arranged on the inner wall of the purification device body (1).

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