Stem cell storage device with graded refrigeration function

Abstract

The utility model discloses a stem cell storage device with a graded refrigeration function, and belongs to the technical field of cell storage. Comprising a storage structure, the back of the storage structure is fixedly connected with a graded refrigeration structure, the graded refrigeration structure comprises a refrigeration shell, the back of the refrigeration shell is provided with a containing groove, one side of the refrigeration shell is fixedly connected with a high-pressure pump, and one side of the high-pressure pump is connected with a liquid nitrogen tank through a pressurization pipeline; one side of the bottom of the liquid nitrogen tank is connected with an evaporator through a nitrogen conveying pipeline, the middle section of the nitrogen conveying pipeline is fixedly connected with an electromagnetic valve, the middle of the bottom of the evaporator is connected with the top of the liquid nitrogen tank through a backflow pipeline, the other side of the evaporator is connected with the storage structure through a conveying pipeline, and one side of the front portion of the refrigeration shell is fixedly connected with a controller. According to the stem cell storage device with the graded refrigeration function, the graded refrigeration effect is achieved, and the problem of long storage time needed by a user is solved.

Description

Technical Field

[0001] The invention relates to the technical field of cell storage, and more specifically to a stem cell storage device with graded refrigeration. Background Art

[0002] A stem cell storage device is a device used to store stem cells. Most existing storage methods use liquid nitrogen. Since liquid nitrogen can quickly freeze the cells, it can effectively prevent stem cell degradation and allow the storage time of stem cells to be longer.

[0003] Existing stem cell storage devices usually use liquid nitrogen direct infusion to freeze and preserve stem cells. If the user does not need to preserve the stem cells for a long time, the stem cells preserved by liquid nitrogen direct infusion need to be thawed, which brings trouble to the user.

[0004] Therefore, it is necessary to provide a stem cell storage device with graded refrigeration to solve the above problems. Utility Model Content

[0005] Based on the above problems existing in the prior art, the purpose of the embodiments of the present application is to provide a stem cell storage device with graded refrigeration to achieve the graded refrigeration effect and solve the storage time problem required by the user.

[0006] The technical solution adopted by the present application to solve its technical problem is: a stem cell storage device with graded refrigeration, including a storage structure, the back of the storage structure is fixedly connected to the graded refrigeration structure, the graded refrigeration structure includes a refrigeration shell, the back of the refrigeration shell is provided with a receiving groove, one side of the refrigeration shell is fixedly connected to a high-pressure pump, one side of the high-pressure pump is connected to a liquid nitrogen tank through a pressurized pipe, one side of the bottom of the liquid nitrogen tank is connected to an evaporator through a nitrogen delivery pipe, the middle section of the nitrogen delivery pipe is fixedly connected to an electromagnetic valve, the middle part of the bottom of the evaporator is connected to the top of the liquid nitrogen tank through a reflux pipe, the other side of the evaporator is connected to the storage structure through a delivery pipe, and one side of the front of the refrigeration shell is fixedly connected to a controller.

[0007] Furthermore, the storage structure includes a containing shell, the top of the back of the containing shell is connected to a cover plate by a hinge, four copper inner cylinders are provided inside the containing shell, the middle parts of the four copper inner cylinders are slidably connected to a stem cell storage tank, the bottoms of the four copper inner cylinders are provided with flow control components, the flow control components include a diverter block, both sides of the diverter block are connected to the delivery pipeline, the front part of the diverter block is connected to the diverter block on the other side through a reflux pipeline, the top of the diverter block is fixedly connected to a flow control outer cylinder, the top of the flow control outer cylinder is slidably connected to a flow barrel, the outer wall of the flow barrel is provided with an elastic part, and the bottom of the flow barrel is fixedly connected to a sealing plate.

[0008] Furthermore, a nitrogen adding pipeline is provided on the top of the liquid nitrogen tank, and the controller can control its evaporator and solenoid valve.

[0009] The beneficial effects of the utility model are:

[0010] First, by providing a graded refrigeration structure, the device can achieve graded refrigeration, so that the user can control the temperature of liquid nitrogen according to the length of time the stem cells are stored, providing convenience for the user.

[0011] Second, by providing the flow control component 105, the user can realize the self-sealing function of the device after taking out the stem cell storage tank 103, preventing the liquid nitrogen inside from continuously evaporating and causing losses to the user. By providing a graded refrigeration structure, the device can realize graded refrigeration, and the user can control the temperature of the liquid nitrogen according to the length of time the stem cells are stored, providing convenience for the user. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] The drawings constituting part of the present invention are used to provide a further understanding of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation on the present invention. In the drawings:

[0013] Figure 1 It is an overall schematic diagram of a stem cell storage device with graded refrigeration in the present application;

[0014] Figure 2 is a cross-sectional schematic diagram of the figure;

[0015] Figure 3 for Figure 2 A schematic cross-sectional view of the central control flow assembly;

[0016] Figure 4 for Figure 1 A cross-sectional schematic diagram of a hierarchical refrigeration structure;

[0017] In the figure: 1. storage structure; 101. containing shell; 102. copper inner cylinder; 103. stem cell storage tank; 104. cover plate; 105. flow control component; 1051. diverter block; 1052. flow control outer cylinder; 1053. flow barrel; 1054. elastic member; 1055. sealing plate; 2. graded refrigeration structure; 201. refrigeration shell; 202. controller; 203. evaporator; 204. liquid nitrogen tank; 205. high-pressure pump; 206. solenoid valve. DETAILED DESCRIPTION

[0018] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0019] It should be noted that, unless otherwise specified, all technical and scientific terms used in this application have the same meanings as commonly understood by ordinary technicians in the technical field to which this application belongs.

[0020] In the present invention, unless otherwise specified, directions such as "up" and "down" are usually relative to the directions shown in the drawings, or relative to the vertical, perpendicular or gravity direction; similarly, for ease of understanding and description, "left" and "right" are usually relative to the left and right shown in the drawings; "inside" and "outside" refer to the inside and outside relative to the outline of each component itself, but the above-mentioned directions are not used to limit the present invention.

[0021] like Figure 1-3 As shown, the present application provides a stem cell storage device with graded refrigeration, including a storage structure 1, a graded refrigeration structure 2 is fixedly connected to the back of the storage structure 1, the graded refrigeration structure 2 includes a refrigeration shell 201, a receiving groove is provided on the back of the refrigeration shell 201, a high-pressure pump 205 is fixedly connected to one side of the refrigeration shell 201, a side of the high-pressure pump 205 is connected to a liquid nitrogen tank 204 through a pressurized pipe, a side of the bottom of the liquid nitrogen tank 204 is connected to an evaporator 203 through a nitrogen delivery pipe, a solenoid valve 206 is fixedly connected to the middle section of the nitrogen delivery pipe, the middle part of the bottom of the evaporator 203 is connected to the top of the liquid nitrogen tank 204 through a reflux pipe, the other side of the evaporator 203 is connected to the storage structure 1 through a delivery pipe, and a controller 202 is fixedly connected to one side of the front of the refrigeration shell 201.

[0022] The storage structure 1 includes a containing shell 101, the top of the back of the containing shell 101 is connected to a cover plate 104 by a hinge, four copper inner cylinders 102 are arranged inside the containing shell 101, the middle parts of the four copper inner cylinders 102 are slidably connected to a stem cell storage tank 103, the bottoms of the four copper inner cylinders 102 are provided with a flow control component 105, the flow control component 105 includes a diverter block 1051, both sides of the diverter block 1051 are connected to the delivery pipeline, the front part of the diverter block 1051 is connected to the diverter block 1051 on the other side through a reflux pipeline, the top of the diverter block 1051 is fixedly connected to a flow control outer cylinder 1052, the top of the flow control outer cylinder 1052 is slidably connected to a flow barrel 1053, the outer wall of the flow barrel 1053 is provided with an elastic member 1054, and the bottom of the flow barrel 1053 is fixedly connected to a sealing plate 1055.

[0023] A nitrogen supply pipeline is provided on the top of the liquid nitrogen tank 204 , and the controller 202 can control the evaporator 203 and the solenoid valve 206 thereof.

[0024] The size of the receiving groove provided on the back of the refrigeration housing 201 matches the size of the liquid nitrogen tank 204 .

[0025] The outer wall of the flow barrel 1053 is fixedly connected with a reset plate, the middle part of the flow barrel 1053 is designed as a through pipe, and a raised frustum-shaped groove body is opened at the bottom of the flow control outer cylinder 1052. The minimum diameter of the raised frustum-shaped groove body is adapted to the minimum diameter of the flow barrel 1053, and the bottom of the flow barrel 1053 slides in the minimum diameter groove of the raised frustum-shaped groove body.

[0026] Working principle:

[0027] Before using the device, first check all major components of the device to ensure that all components of the device cooperate normally and that the device can work normally. When the user needs to preserve the stem cells for a long time, the controller 202 controls the evaporator 203 not to operate, and starts the high-pressure pump 205 to increase the pressure in the liquid nitrogen tank 204. The liquid nitrogen in the liquid nitrogen tank 204 enters the evaporator 203 through the nitrogen delivery pipeline and is delivered to the cavity in the storage structure 1 through the delivery pipeline connected to the other end of the evaporator 203 to achieve long-term freezing of the stem cells. When the user When it is necessary to freeze the stem cells in a short time, the high-pressure pump 205 is started and the solenoid valve 206 and the evaporator 203 are controlled by the controller 202. The solenoid valve 206 limits the flow rate of liquid nitrogen in the liquid nitrogen tank 204, and the liquid nitrogen is heated by the evaporator 203 to gasify the liquid nitrogen. The gasified liquid nitrogen enters the cavity in the storage structure 1 through the conveying pipeline, so that the stem cells in the storage structure 1 are refrigerated and stored. By providing the graded refrigeration structure 2, the graded refrigeration of the device can be realized, so that the user can control the temperature of the liquid nitrogen according to the storage time of the stem cells, which provides convenience for the user.

[0028] When the user needs to take out the stem cell storage tank 103, the stem cell storage tank 103 no longer presses the flow barrel 1053. When the stem cell storage tank 103 no longer presses the flow barrel 1053, the elastic member 1054 pushes the flow barrel 1053 to rebound. The rebound of the flow barrel 1053 drives the sealing plate 1055 to move upward. The sealing plate 1055 moves upward to seal the flow control outer cylinder 1052. By providing the flow control component 105, the user can realize the self-sealing function of the device after taking out the stem cell storage tank 103, thereby preventing the liquid nitrogen inside from continuing to evaporate and causing losses to the user.

[0029] Obviously, the above-described embodiments are only a part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present invention.

[0030] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, devices, components and / or combinations thereof.

[0031] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the numbers used in this way can be interchanged where appropriate, so that the embodiments of the present application described herein can be implemented in an order other than those illustrated or described herein.

[0032] The above description is only the preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

[0033] The above is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments. All technical solutions under the concept of the present invention belong to the protection scope of the present invention. It should be pointed out that for ordinary technicians in this technical field, some improvements and modifications without departing from the principle of the present invention should also be regarded as the protection scope of the present invention.

Claims

1. A stem cell storage device with graded refrigeration, characterized in that: The invention comprises a storage structure (1), wherein the back of the storage structure (1) is fixedly connected to a hierarchical refrigeration structure (2), wherein the hierarchical refrigeration structure (2) comprises a refrigeration shell (201), wherein the back of the refrigeration shell (201) is provided with a receiving groove, wherein one side of the refrigeration shell (201) is fixedly connected to a high-pressure pump (205), wherein one side of the high-pressure pump (205) is connected to a liquid nitrogen tank (204) via a pressurized pipeline, wherein one side of the bottom of the liquid nitrogen tank (204) is connected to an evaporator (203) via a nitrogen delivery pipeline, wherein the middle section of the nitrogen delivery pipeline is fixedly connected to an electromagnetic valve (206), wherein the middle section of the bottom of the evaporator (203) is connected to the top of the liquid nitrogen tank (204) via a reflux pipeline, wherein the other side of the evaporator (203) is connected to the storage structure (1) via a delivery pipeline, and wherein one side of the front section of the refrigeration shell (201) is fixedly connected to a controller (202).

2. A stem cell storage device with graded refrigeration according to claim 1, characterized in that: The storage structure (1) comprises a housing (101), the top of the back of the housing (101) is connected to a cover plate (104) via a hinge, four copper inner cylinders (102) are arranged inside the housing (101), the middle of the four copper inner cylinders (102) are slidably connected to a stem cell storage tank (103), and the bottom of the four copper inner cylinders (102) are provided with a flow control component (105), the flow control component (105) comprises a diverter block (1051), and the diverter block Both sides of (1051) are connected to the delivery pipeline, the front part of the diverter block (1051) is connected to the diverter block (1051) on the other side through a counterflow pipeline, the top of the diverter block (1051) is fixedly connected to a flow control outer cylinder (1052), the top of the flow control outer cylinder (1052) is slidably connected to a flow barrel (1053), the outer wall of the flow barrel (1053) is provided with an elastic member (1054), and the bottom of the flow barrel (1053) is fixedly connected to a sealing plate (1055).

3. The stem cell storage device with graded refrigeration according to claim 1, characterized in that: A nitrogen supply pipeline is provided on the top of the liquid nitrogen tank (204), and the controller (202) can control the evaporator (203) and the solenoid valve (206) thereof.

4. The stem cell storage device with graded refrigeration according to claim 1, characterized in that: The size of the receiving groove provided on the back of the refrigeration housing (201) is compatible with the size of the liquid nitrogen tank (204).

5. The stem cell storage device with graded refrigeration according to claim 2, characterized in that: The outer wall of the flow barrel (1053) is fixedly connected with a reset plate, the middle part of the flow barrel (1053) is designed as a through pipe, and the bottom of the flow control outer cylinder (1052) is provided with a raised frustum-shaped groove body, the minimum diameter of the raised frustum-shaped groove body is matched with the minimum diameter of the flow barrel (1053), and the bottom of the flow barrel (1053) slides in the minimum diameter groove of the raised frustum-shaped groove body.

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