Covered grid stent manufacturing device

Abstract

The utility model provides a film-covered grid support manufacturing device, which relates to the field of medical instruments and is used for manufacturing a film-covered grid support. The film-covered grid stent comprises a grid type bare stent and a covering film, the grid-type bare stent is woven into a cylindrical shape by metal wires, and the covering film is connected to the peripheral face of the grid-type bare stent and is in a honeycomb shape with a plurality of meshes. According to the utility model, the technical problem that high flexibility of a peripheral stent and delaying of secondary stenosis of blood vessels cannot be compatible in the prior art is solved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, in particular to a device for manufacturing a membrane-covered grid stent. Background Art

[0002] Currently, for small blood vessel (peripheral blood vessel) stenosis lesions, stents are usually implanted at the lesion site to open the stenotic blood vessels and promote blood flow supply to the stenotic area, thereby achieving the purpose of treating the disease.

[0003] Peripheral stents used for implantation are mainly divided into two types: bare stents and covered stents. Among them, for bare stents, currently they mainly include photolithographic stents and braided stents. Photolithographic stents are made by laser cutting metal tubes. Although this type of stent can effectively inhibit endothelial cell proliferation, it has poor flexibility due to its non-circular cross-section and cannot be used in tortuous and narrow blood vessels; braided stents are woven from wire materials, and their cross-section is circular, which has higher flexibility, but due to the limitations of the braiding method, the braided stent has poor support and is prone to secondary stenosis of blood vessels. For covered stents, the coating is mostly made of polymer materials (such as expanded polytetrafluoroethylene). Since the current covered stents are generally cylindrical with a sealed circumference, endothelial cells can only grow from the openings at both ends of the covered stent to the inside of the covered stent, resulting in the easy formation of proliferative tissue inside the covered stent, which in turn is also prone to secondary stenosis of blood vessels. Utility Model Content

[0004] The purpose of the utility model is to provide a device for manufacturing a coated mesh stent, so as to alleviate the technical problem in the prior art that the high flexibility of the peripheral stent is incompatible with the delay of secondary stenosis of the blood vessel.

[0005] To achieve the above objectives, the present invention adopts the following technical solutions:

[0006] In the first aspect, an embodiment of the utility model provides a coated grid stent, comprising a mesh bare stent and a coating; the mesh bare stent is woven into a cylindrical shape by metal wires, the coating is connected to the circumference of the mesh bare stent, and the coating is in a honeycomb shape with multiple meshes.

[0007] In the coated mesh stent provided in this embodiment, the skeleton is a mesh bare stent woven from metal wires, which has better flexibility compared to a photolithographic stent as a skeleton. Since a coating is also provided, the coating will limit the excessive deformation of the mesh bare stent, thereby improving the support of the mesh bare stent. Thus, the coated mesh stent can achieve a better compatibility effect between high flexibility and good support. In addition, since the coating is provided with a mesh, after being implanted into the patient's body, endothelial cells can not only grow from the openings at both ends of the coated mesh stent to the inside of the coated stent, but can also attach to each cell on the circumference of the mesh coated stent exposed by the mesh of the coating, thereby reducing the proliferative tissue inside the stent, thereby delaying the secondary stenosis of the blood vessels caused by the endothelial cells only being able to grow from the openings at both ends of the coated stent to the inside of the coated stent.

[0008] In summary, the coated mesh stent provided in this embodiment alleviates the technical problem in the prior art of the incompatibility between the high flexibility of the peripheral stent and the prevention of secondary vascular stenosis.

[0009] In an optional implementation manner of this embodiment, more preferably, the meshes of the coating are arranged in a one-to-one correspondence within each cell on the circumference of the grid-type bare stent.

[0010] In a second aspect, an embodiment of the present invention provides a device for manufacturing a coated mesh stent, which is used to manufacture the coated mesh stent described in any one of the aforementioned embodiments.

[0011] Specifically, the film-covered grid stent manufacturing device includes a fixing cap and a film-covered body;

[0012] One end of the fixing cap is closed and the other end is open;

[0013] The membrane body includes a hollow cylindrical body and a negative pressure joint; one end of the hollow cylindrical body in the axial direction is the upper end, and the other end is the lower end: the open end of the fixing cap is connected to and closed at the lower end of the hollow cylindrical body in a detachable manner, and the fixing cap is circumferentially and axially limited to the hollow cylindrical body; the negative pressure joint is integrally connected to the upper end of the hollow cylindrical body and is in communication with the internal cavity of the hollow cylindrical body; the circumferential surface of the hollow cylindrical body is provided with negative pressure suction holes that match the membrane mesh;

[0014] A plurality of triangular raised fixing portions are respectively provided on the outer circumferential surface of the upper end of the hollow cylindrical body and the outer circumferential surface of the open end of the fixing cap, which are arranged at intervals along their respective circumferential directions. The orientations of the triangular raised fixing portions are configured so that, when the open end of the fixing cap is docked and closed to the lower end of the hollow cylindrical body, they can cooperate with the convex and concave ends of the mesh-type bare bracket sleeved on the outside of the hollow cylindrical body to limit the mesh-type bare bracket.

[0015] In an optional implementation manner of this embodiment, more preferably, a circumferential gap is provided between each two adjacent triangular raised fixing portions.

[0016] Further preferably, a serrated groove is provided on the outer circumferential surface of the lower end of the hollow cylindrical body. When the open end of the fixing cap is docked and closed to the lower end of the hollow cylindrical body, the serrated groove and the triangular raised fixing portion provided on the outer circumferential surface of the open end of the fixing cap are matched in a concave-convex manner.

[0017] In an optional implementation of this embodiment, it is more preferred that an annular fixing cap groove is provided on the inner circumference of the open end of the fixing cap, and an axial protruding connecting portion is provided on the lower end of the hollow cylindrical body. When the open end of the fixing cap is docked and closed to the lower end of the hollow cylindrical body, the axial protruding connecting portion is inserted into the interior of the open end of the fixing cap and is clamped in the annular fixing cap groove.

[0018] Further preferably, an annular or C-shaped elastic member is fixedly connected or axially limitedly connected to the outer peripheral surface of the axial protruding connecting portion, and in the assembled state, the elastic member is snapped into the annular groove of the fixing cap.

[0019] More preferably, an annular groove of the coating body is provided on the outer peripheral surface of the axial protruding connecting portion, and the elastic member is embedded in the annular groove of the coating body.

[0020] In addition, in an optional implementation manner of this embodiment, more preferably, the outer peripheral surface of the closed end of the fixing cap is hemispherical.

[0021] In an optional implementation manner of this embodiment, more preferably, the negative pressure joint is connected to the upper end of the hollow cylindrical body through a conical arc transition surface with a diameter gradually decreasing from the lower end to the upper end. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the specific implementation methods of the utility model or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0023] Figure 1 A schematic diagram of the overall structure of the membrane-covered grid stent provided in an embodiment of the present invention;

[0024] Figure 2 A schematic diagram of the overall structure of the membrane-covered grid stent manufacturing device provided by an embodiment of the present invention in an assembled state;

[0025] Figure 3 A schematic diagram of the overall structure of the membrane body in the membrane mesh stent manufacturing device provided by an embodiment of the present invention;

[0026] Figure 4 A cross-sectional view of the overall structure of the membrane body in the membrane mesh stent manufacturing device provided by an embodiment of the present invention;

[0027] Figure 5 This is an axonometric view of the local structure of the lower end of the cylindrical main body of the membrane;

[0028] Figure 6 A schematic diagram of the overall structure of the fixing cap in the device for manufacturing the coated mesh stent provided by an embodiment of the present invention;

[0029] Figure 7 A diagram showing the relationship between the coated mesh stent manufacturing device provided by an embodiment of the present invention and the mesh bare stent in the assembled state;

[0030] Figure 8 for Figure 7 Schematic diagram of the explosion structure;

[0031] Figure 9 for Figure 7 , an enlarged view of the local structure of the joint between the lower end of the cylindrical main body of the membrane and the fixing cap;

[0032] Figure 10 A schematic diagram of the usage of the film-coated grid stent manufacturing device provided in an embodiment of the present invention.

[0033] Icons: 11-grid bare bracket; 12-film; 121-mesh; 21-fixing cap; 22-film body; 221-hollow cylindrical main body; 2211-negative pressure suction hole; 222-negative pressure joint; 23-triangular raised fixing part; 24-serrated groove; 25-annular slot of fixing cap; 26-axial raised connecting part; 27-elastic part; 28-annular slot of film body; 29-conical arc transition surface. DETAILED DESCRIPTION

[0034] To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Generally, the components of the embodiments of the present invention described and shown in the drawings herein can be arranged and designed in various different configurations.

[0035] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but rather merely represents selected embodiments of the present invention. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without creative effort are also within the scope of protection of the present invention.

[0036] It should be noted that like reference numerals and letters denote similar items in the drawings, and therefore, once an item is defined in one drawing, it does not require further definition or explanation in subsequent drawings.

[0037] In the description of this utility model, it should be noted that the terms "upper," "lower," "inner," and "outer," etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, or are the orientations or positional relationships in which the utility model product is typically placed when in use. These terms are intended solely to facilitate the description of this utility model and simplify the description, and are not intended to indicate or imply that the devices or components referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on this utility model. Furthermore, the terms "first," "second," etc., etc., are used solely for distinction and should not be construed as indicating or implying relative importance.

[0038] It should also be noted that, in the description of this utility model, unless otherwise expressly specified or limited, the terms "disposed," "installed," and "connected" should be understood broadly. For example, they may refer to fixed connections, detachable connections, or integral connections; they may refer to direct connections, indirect connections through an intermediate medium, or internal connections between two components. Those skilled in the art will understand the specific meanings of these terms in this utility model based on the specific circumstances.

[0039] The following embodiments of the present invention are described in detail with reference to the accompanying drawings. In the absence of conflict, the following embodiments and features in the embodiments may be combined with each other.

[0040] Example 1

[0041] This embodiment provides a coated mesh stent, referring to Figure 1 The coated grid stent includes a mesh bare stent 11 and a coating 12; the mesh bare stent 11 is woven into a cylindrical shape by metal wires, the coating 12 is connected to the circumference of the mesh bare stent 11, and the coating 12 is a honeycomb shape with multiple meshes 121.

[0042] In the coated mesh stent provided in this embodiment, the skeleton is a mesh bare stent 11 woven from metal wires. Compared with the photolithographic stent as the skeleton, the flexibility is better. Since there is also a coating, the coating will limit the deformation of the mesh bare stent, thereby improving the support of the mesh bare stent. Therefore, the coated mesh stent can achieve a better compatibility effect between high flexibility and good support. In addition, since the coating 12 is provided with a mesh 121, after being implanted into the patient's body, the endothelial cells can not only grow from the openings at both ends of the coated mesh stent to the inside of the coated stent, but also attach to each cell on the circumference of the mesh coated 12 stent exposed at the mesh 121 of the coating 12, thereby reducing the proliferative tissue inside the stent, thereby delaying the secondary stenosis of the blood vessels caused by the endothelial cells only being able to grow from the openings at both ends of the coated stent to the inside of the coated stent.

[0043] In summary, the coated mesh stent provided in this embodiment alleviates the technical problem in the prior art of the incompatibility between the high flexibility of the peripheral stent and the delay of secondary vascular stenosis.

[0044] In this embodiment, the meshes 121 of the coating 12 may correspond to the intersections between adjacent cells on the circumference of the mesh bare stent 11, or may be arranged correspondingly within each cell, or a portion may correspond to the intersections and a portion may correspond to each cell. Preferably, the meshes 121 of the coating 12 are arranged one-to-one in each cell on the circumference of the mesh bare stent 11. In this way, the coating 12 limits the intersections of each cell of the mesh bare stent 11 and limits the relative rotation between the braided filaments at each intersection, thereby ensuring the flexibility of the stent while improving the supporting force.

[0045] Example 2

[0046] This embodiment provides a device for manufacturing a coated mesh stent, which is used to manufacture the coated mesh stent provided by any optional implementation manner in Example 1.

[0047] Specifically, refer to Figures 2 to 10The membrane grid bracket manufacturing device includes a fixing cap 21 and a membrane body 22. The fixing cap 21 is closed at one end and open at the other end. The membrane body 22 includes a hollow cylindrical main body 221 and a negative pressure joint 222; in detail, one axial end of the hollow cylindrical main body 221 is the upper end and the other end is the lower end: the open end of the fixing cap 21 is connected to and closed at the lower end of the hollow cylindrical main body 221 in a detachable manner, and the fixing cap 21 is circumferentially and axially limited to the hollow cylindrical main body 221; the negative pressure joint 222 is integrally connected to the upper end of the hollow cylindrical main body 221, and the negative pressure joint 222 is connected to the internal cavity of the hollow cylindrical main body 221; the circumferential surface of the hollow cylindrical main body 221 is provided with negative pressure suction holes 2211 that match the mesh 121 of the membrane 12. A plurality of triangular raised fixing portions 23 arranged at intervals along their respective circumferential directions are respectively provided on the outer circumferential surface of the upper end of the hollow cylindrical main body 221 and the outer circumferential surface of the open end of the fixing cap 21. The orientation of the triangular raised fixing portions 23 is configured so that, when the fixing cap 21 is connected to the open end and closed to the lower end of the hollow cylindrical main body 221, they can cooperate with the convex and concave ends of the mesh bare bracket 11 mounted on the outside of the hollow cylindrical main body 221 to limit the mesh bare bracket 11.

[0048] When manufacturing the coated mesh stent described in Example 1, Figures 7 to 9 As shown, the grid-type bare bracket 11 is sleeved on the outside of the hollow cylindrical main body 221, so that the upper end of the grid-type bare bracket 11 is matched with the multiple triangular protruding fixing parts 23 provided on the outer peripheral surface of the upper end of the hollow cylindrical main body 221, and the open end of the fixing cap 21 is docked and sealed on the lower end of the hollow cylindrical main body 221. The fixing cap 21 is limited circumferentially and axially to the hollow cylindrical main body 221, so that the lower end of the grid-type bare bracket 11 is matched with the multiple triangular protruding fixing parts 23 provided on the outer peripheral surface of the open end of the fixing cap 21 to limit the grid-type bare bracket 11 circumferentially and axially; then, as shown Figure 10 As shown, a vent pipe is connected to the negative pressure connector 222, and the other end of the vent pipe is connected to the negative pressure device; Figure 7 The structure shown is immersed in the coating solution as a whole. After that, the device is lifted out of the coating solution. Before the coating solution dries up and forms a film, the negative pressure device is turned on. The coating solution attached to the cells of the grid-type bare bracket 11 will be sucked into the cavity of the hollow cylindrical main body 221 through the negative pressure suction hole 2211 under negative pressure, and the excess coating solution flows down. After the coating solution dries up and forms a film, the coated grid-type bare bracket 11 is removed, and the coated grid bracket is completed.

[0049] The coated mesh stent fabrication device provided in this embodiment is simple to use, and the membrane is broken before film formation, which helps ensure that the meshes 121 on the final coated mesh stent coating 12 are evenly distributed. In addition, in the above-mentioned fabrication method, drugs such as paclitaxel and rapamycin that inhibit endothelial cell proliferation can be added to the coating solution, thereby enabling the resulting coated mesh stent to further delay vascular restenosis.

[0050] In addition, in an optional implementation manner of this embodiment, it is more preferred that Figure 6 and Figure 7 As shown, a circumferential gap is provided between each two adjacent triangular protruding fixing portions 23 , which is conducive to allowing excess coating solution to quickly flow down from the circumferential gap during the above-mentioned manufacturing steps.

[0051] Further preferably, a serrated groove 24 is provided on the outer circumferential surface of the lower end of the hollow cylindrical main body 221. In the assembled state where the open end of the fixing cap 21 is docked and closed to the lower end of the hollow cylindrical main body 221, the serrated groove 24 is matched with the triangular raised fixing portion 23 provided on the outer circumferential surface of the open end of the fixing cap 21. Therefore, in the assembled state, the fixing cap 21 can be circumferentially limited by the serrated groove 24 to prevent the fixing cap 21 from rotating, thereby further limiting the circumferential rotation of the grid-type bare bracket 11.

[0052] In the optional implementation of this embodiment, there are many specific assembly methods for the open end of the fixing cap 21 to be docked and closed at the lower end of the hollow cylindrical body 221. Among them, in order to avoid axial separation of the two after assembly, it is more preferred, such as Figures 2 to 6 As shown, the inner circumference of the open end of the fixing cap 21 is provided with a fixing cap annular groove 25, and the lower end of the hollow cylindrical main body 221 is provided with an axial protrusion connecting portion 26. When the open end of the fixing cap 21 is docked and closed to the lower end of the hollow cylindrical main body 221, the axial protrusion connecting portion 26 is inserted into the inside of the open end of the fixing cap 21 and is clamped in the fixing cap annular groove 25, so that quick assembly can be achieved while ensuring axial limitation, preventing the two from axially separating after the open end of the fixing cap 21 is docked and closed to the lower end of the hollow cylindrical main body 221.

[0053] After the axial protrusion connecting portion 26 is inserted into the interior of the open end of the fixing cap 21, there are many specific clamping structures for clamping the annular clamping groove 25 of the fixing cap, among which, preferably but not limited to, continue to refer to Figures 2 to 6 An annular or C-shaped elastic member 27 is fixedly connected or axially limitedly connected to the outer peripheral surface of the axial protruding connecting portion 26. In the assembled state, the elastic member 27 is snapped into the annular groove 25 of the fixing cap.

[0054] More preferably, an outer peripheral surface of the axial protruding connecting portion 26 is provided with a film body annular groove 28 , and the elastic member 27 is embedded in the film body annular groove 28 .

[0055] In addition, in an optional implementation of the present embodiment, it is more preferred that the outer peripheral surface of the closed end of the fixed cap 21 is hemispherical; it is more preferred that the negative pressure joint 222 is connected to the upper end of the hollow cylindrical body 221 through a conical arc transition surface 29 whose diameter gradually decreases from the lower end to the upper end. The above structures are beneficial to allowing excess coating solution to be quickly diverted and dropped during the manufacturing process.

[0056] Finally, it should be noted that: the various embodiments in this specification are described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the various embodiments can be referred to each other; the above embodiments in this specification are only used to illustrate the technical solution of the utility model, rather than to limit it; although the utility model is described in detail with reference to the aforementioned embodiments, ordinary technicians in this field should understand that: it is still possible to modify the technical solutions recorded in the aforementioned embodiments, or to replace some or all of the technical features therein with equivalents; and these modifications or replacements do not cause the essence of the corresponding technical solution to deviate from the scope of the technical solution of the various embodiments of the utility model.

Claims

1. A coated mesh stent manufacturing device, used for manufacturing a coated mesh stent, the coated mesh stent comprising a mesh bare stent (11) and a coating (12); the mesh bare stent (11) is woven into a cylindrical shape by metal wires, the coating (12) is connected to the circumference of the mesh bare stent (11), and the coating (12) is in a honeycomb shape with a plurality of meshes (121); the characteristics are: The film-covered grid stent manufacturing device comprises a fixing cap (21) and a film-covered body (22); The fixing cap (21) has one end closed and the other end open; The membrane body (22) comprises a hollow cylindrical main body (221) and a negative pressure joint (222); one axial end of the hollow cylindrical main body (221) is the upper end, and the other end is the lower end; the open end of the fixing cap (21) is connected to and sealed at the lower end of the hollow cylindrical main body (221) in a detachable manner, and the fixing cap (21) is circumferentially and axially limited to the hollow cylindrical main body (221); the negative pressure joint (222) is integrally connected to the upper end of the hollow cylindrical main body (221) and communicates with the internal cavity of the hollow cylindrical main body (221); the circumferential surface of the hollow cylindrical main body (221) is provided with negative pressure suction holes (2211) matching the mesh (121) of the membrane (12); A plurality of triangular raised fixing portions (23) are respectively arranged at intervals along their respective circumferential directions on the outer circumferential surface of the upper end of the hollow cylindrical body (221) and the outer circumferential surface of the open end of the fixing cap (21). The orientation of the triangular raised fixing portions (23) is configured so that, when the fixing cap (21) is connected to the open end and sealed to the lower end of the hollow cylindrical body (221), the fixing portions (23) can be matched with the end of the mesh bare bracket (11) sleeved on the outside of the hollow cylindrical body (221) in a concave-convex manner, so as to limit the mesh bare bracket (11).

2. The film-covered grid stent manufacturing device according to claim 1, characterized in that: A circumferential gap is provided between each two adjacent triangular raised fixing portions (23).

3. The film-covered grid stent manufacturing device according to claim 2, characterized in that: A sawtooth groove (24) is provided on the outer circumferential surface of the lower end of the hollow cylindrical body (221); when the opening end of the fixing cap (21) is butted against and sealed to the lower end of the hollow cylindrical body (221), the sawtooth groove (24) and the triangular raised fixing portion (23) provided on the outer circumferential surface of the opening end of the fixing cap (21) are matched in a concave-convex manner.

4. The film-covered grid stent manufacturing device according to claim 1, characterized in that: The inner circumferential surface of the open end of the fixing cap (21) is provided with a fixing cap annular groove (25), and the lower end of the hollow cylindrical body (221) is provided with an axial protruding connecting portion (26). When the open end of the fixing cap (21) is butted against and sealed to the lower end of the hollow cylindrical body (221), the axial protruding connecting portion (26) is inserted into the interior of the open end of the fixing cap (21) and is clamped in the fixing cap annular groove (25).

5. The film-covered grid stent manufacturing device according to claim 4, characterized in that: An annular or C-shaped elastic member (27) is fixedly connected or axially limitedly connected to the outer peripheral surface of the axial protruding connection portion (26); in the assembled state, the elastic member (27) is snapped into the annular snap groove (25) of the fixing cap.

6. The film-covered grid stent manufacturing device according to claim 5, characterized in that: The outer peripheral surface of the axial protruding connection portion (26) is provided with a coating body annular groove (28), and the elastic member (27) is embedded in the coating body annular groove (28).

7. The film-covered grid stent manufacturing device according to claim 1, characterized in that: The outer peripheral surface of the closed end of the fixing cap (21) is hemispherical.

8. The film-covered grid stent manufacturing device according to claim 1, characterized in that: The negative pressure joint (222) is connected to the upper end of the hollow cylindrical body (221) via a conical arc transition surface (29) whose diameter gradually decreases from the lower end to the upper end.

Images