Drying device and drying system thereof

Abstract

The utility model provides a drying device and a drying system thereof. The drying device comprises a drying box, a feeding pipe, a discharging pipe, a nitrogen port, an exhaust pipe, a hot water pipe and a filtering unit. The exhaust pipe is arranged at the top of the drying box; the nitrogen port is formed in the bottom of the drying box; the filtering unit is arranged in the drying box; the hot water pipe enters the drying box, is in contact with the outer side of the filtering unit, and then penetrates through the outer wall of the drying box to reach the outside of the drying box; the feeding pipe and the discharging pipe penetrate through the outer wall of the drying box and are connected with the filtering unit.

Description

Technical Field

[0001] The utility model relates to the technical field of medicine drying, in particular to a drying device and a drying system thereof. Background Art

[0002] Solution crystallization is generally the most common way to purify raw materials. Through filtering equipment such as screens or filters, solid-liquid separation can be quickly achieved to screen out the raw materials. In order to quickly remove the residual solvent on the raw materials, oven drying is generally used. However, for some APIs, drying in the air will inevitably come into contact with oxygen in the air, and then react to produce by-products, thus affecting the quality control of the drugs. A certain degree of nitrogen protection can be achieved by continuously passing nitrogen into the oven. However, it is impossible to meet the low oxygen and low moisture nitrogen protection throughout the drying process. At the same time, continuous nitrogen flow causes nitrogen waste. The continuous flow of nitrogen takes away a lot of heat, the drying effect is poor, and the drying time is prolonged. Summary of the invention

[0003] In order to solve the above problems, the utility model provides a drying device, including a drying box, a feed pipe, a discharge pipe, a nitrogen port, an exhaust pipe, a hot water pipe, and a filter unit; the exhaust pipe is provided on the top of the drying box; the nitrogen port is provided at the bottom of the drying box; the filter unit is provided in the drying box; the hot water pipe enters the drying box, contacts with the outside of the filter unit, and then penetrates the outer wall of the drying box to reach the outside of the drying box; the feed pipe and the discharge pipe respectively penetrate the outer wall of the drying box and are connected with the filter unit.

[0004] Preferably, a filter inlet and a filter outlet are provided on the filter unit, wherein the filter inlet is close to the top of the filter unit and the filter outlet is close to the bottom of the filter unit. A filter unit is further provided inside the filter unit and is located between the filter inlet and the filter outlet.

[0005] Preferably, an inclined plate is provided below the filter unit, and the inclined plate is inclined toward the filter outlet.

[0006] Preferably, the hot water pipe is in contact with the outer side of the filter unit in a winding manner.

[0007] Preferably, the feed pipe is connected to the filter inlet through a hose, and the discharge pipe is connected to the filter outlet through a hose.

[0008] Preferably, a temperature sensor and / or an air pressure sensor is provided in the drying box.

[0009] The utility model also provides a drying system, including the drying device, a nitrogen buffer device, a nitrogen delivery pipeline 1, a nitrogen delivery pipeline 2, and a nitrogen return flow channel; the nitrogen buffer device is connected with the feed pipe through the nitrogen delivery pipeline 1, is connected with the nitrogen port through the nitrogen delivery pipeline 2, and is connected with the discharge pipe through the nitrogen return flow channel.

[0010] Preferably, a heating device is provided in the nitrogen buffer device.

[0011] Preferably, a temperature sensor is provided on the nitrogen delivery pipeline.

[0012] Preferably, a gas sensor and / or an air pressure sensor is provided on the exhaust pipe. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 is a schematic diagram of a drying device in one embodiment;

[0014] Figure 2 FIG. 1 is a schematic diagram of a drying system in one embodiment.

[0015] Explanation of the reference numerals: drying box 1, filter unit 2, filter unit 201, inclined plate 202, feed pipe 301, hose 302, nitrogen port 303, discharge pipe 304, hot water pipe 305, exhaust pipe 306, nitrogen buffer device 4, nitrogen delivery pipeline 1 401, nitrogen delivery pipeline 2 402, nitrogen return flow channel 403; sensor 5. DETAILED DESCRIPTION

[0016] Unless otherwise specified, the experimental methods used in the following examples are conventional methods.

[0017] Unless otherwise specified, the materials and reagents used in the following examples are all common commercial products and can be purchased on the market.

[0018] The present invention will be further described below through embodiments, which are not intended to further limit the content of the present invention. Those skilled in the art should understand that equivalent replacements or corresponding improvements made to the content of the present invention still fall within the scope of protection of the present invention.

[0019] A drying device, such as Figure 1As shown, it includes a drying box 1, a feed pipe 301, a discharge pipe 304, a nitrogen port 303, an exhaust pipe 306, a hot water pipe 305, and a filter unit 2; the exhaust pipe 306 is provided on the top of the drying box 1; the nitrogen port 303 is provided at the bottom of the drying box 1; the filter unit 2 is provided in the drying box 1; the hot water pipe 305 enters the drying box 1, contacts the outside of the filter unit 2, and then penetrates the outer wall of the drying box 1 to reach the outside of the drying box 1; the feed pipe 301 and the discharge pipe 304 respectively penetrate the outer wall of the drying box 1 and are connected with the filter unit 2.

[0020] When working, the exhaust device extracts the air in the drying box 1 through the exhaust pipe 306, and nitrogen is introduced into the drying box 1 through the nitrogen port 303 at the right time. When the nitrogen fills the drying box 1, the exhaust pipe 306 and the nitrogen port 303 are closed, so that the drying box 1 is in a nitrogen atmosphere. Alternatively, the exhaust pipe 306 and the nitrogen port 303 can be kept open, and nitrogen is continuously introduced from the nitrogen port 303, so that the drying box 1 is in a nitrogen atmosphere.

[0021] Under nitrogen atmosphere, the feed liquid enters the filter unit 2 through the feed pipe 301, and the solid is discharged through the discharge pipe 304 after being filtered out, and the solid in the filter unit 2 is dried at high temperature. The temperature increase in the filter unit 2 can be provided by the hot water in the hot water pipe 305, and another heating device can also be set in the drying box 1 for further heating.

[0022] In a preferred embodiment, a filter inlet and a filter outlet are provided on the filter unit 2, wherein the filter inlet is close to the top of the filter unit 2, and the filter outlet is close to the bottom of the filter unit 2. A filter unit 201 is also provided inside the filter unit 2, located between the filter inlet and the filter outlet.

[0023] In a preferred embodiment, an inclined plate 202 is provided below the filter unit 2, and the inclined plate 202 is inclined toward the filter outlet.

[0024] In a preferred embodiment, the hot water pipe 305 is in contact with the outer side of the filter unit 2 in a winding manner.

[0025] In a preferred embodiment, the feed pipe 301 is connected to the filter inlet through a hose 302 , and the discharge pipe 304 is connected to the filter outlet through a hose 302 .

[0026] In a preferred embodiment, a temperature sensor and / or an air pressure sensor is provided in the drying box 1 to sense the temperature and / or air pressure in the drying box 1 .

[0027] A drying system such as Figure 2As shown, it includes the drying device, the nitrogen buffer device 4, the nitrogen delivery pipeline 1 401, the nitrogen delivery pipeline 2 402, and the nitrogen return flow channel 403; the nitrogen buffer device 4 is connected with the feed pipe 301 through the nitrogen delivery pipeline 1 401, is connected with the nitrogen port 303 through the nitrogen delivery pipeline 2 402, and is connected with the discharge pipe 304 through the nitrogen return flow channel 403.

[0028] When the drying system is working, the exhaust pipe 306 and the discharge pipe 304 are opened, and the nitrogen is first heated by the nitrogen buffer device 4, and then passes through the nitrogen delivery pipe 1 401 and the nitrogen delivery pipe 2 402, and enters the drying box 1 and the filter unit 2, and the air is discharged through the exhaust pipe 306 and the discharge pipe 304. After that, the feed liquid enters the filter unit 2 through the feed pipe 301 and is discharged through the discharge pipe 304 after being filtered. During this period, the nitrogen continues to be introduced along the nitrogen delivery pipe 1 401 and refluxes through the nitrogen reflux channel 403, and the exhaust pipe 306 can be closed or kept open. When the exhaust pipe 306 is opened, the nitrogen continues to be introduced through the nitrogen port 303.

[0029] In a preferred embodiment, a heating device is provided in the nitrogen buffer device 4 .

[0030] In a preferred embodiment, the drying system includes a sensor 5, and one or more of a temperature sensor, a gas sensor, and an air pressure sensor may be selected according to detection requirements.

[0031] In a preferred embodiment, a temperature sensor is provided on the nitrogen delivery pipeline 1 401 .

[0032] In a preferred embodiment, the exhaust pipe 306 is provided with a gas sensor and / or an air pressure sensor.

Claims

1. A drying device, characterized in that: Including drying box, feed pipe, discharge pipe, nitrogen port, exhaust pipe, hot water pipe, filter unit; The exhaust pipe is arranged on the top of the drying box; The nitrogen inlet is arranged at the bottom of the drying box; The filtering unit is arranged in the drying box; The hot water pipe enters the drying box, contacts the outside of the filter unit, and then passes through the outer wall of the drying box to reach the outside of the drying box; The feed pipe and the discharge pipe respectively penetrate the outer wall of the drying box and are connected with the filter unit.

2. The drying device according to claim 1, characterized in that: The filter unit is provided with a filter inlet and a filter outlet, wherein the filter inlet is close to the top of the filter unit and the filter outlet is close to the bottom of the filter unit. A filter unit is further provided inside the filter unit and is located between the filter inlet and the filter outlet.

3. The drying device according to claim 2, characterized in that: An inclined plate is provided below the filter unit, and the inclined plate is inclined toward the filter outlet.

4. The drying device according to claim 3, characterized in that: The hot water pipe is in contact with the outer side of the filter unit in a winding manner.

5. The drying device according to claim 4, characterized in that: The feed pipe is connected to the filter inlet through a hose, and the discharge pipe is connected to the filter outlet through a hose.

6. The drying device according to claim 5, characterized in that: A temperature sensor and / or an air pressure sensor is arranged in the drying box.

7. A drying system, characterized in that: It comprises the drying device according to any one of claims 1 to 6, a nitrogen buffer device, a nitrogen delivery pipeline 1, a nitrogen delivery pipeline 2, and a nitrogen return flow channel; The nitrogen buffer device is connected to the feed pipe through the nitrogen delivery pipeline 1, is connected to the nitrogen port through the nitrogen delivery pipeline 2, and is connected to the discharge pipe through the nitrogen return flow channel.

8. The drying system according to claim 7, characterized in that: A heating device is provided in the nitrogen buffer device.

9. The drying system according to claim 8, characterized in that: A temperature sensor is arranged on the nitrogen delivery pipeline.

10. The drying system according to claim 9, characterized in that: The exhaust pipe is provided with a gas sensor and / or an air pressure sensor.

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