Liquid adding device for immunohistochemical dyeing machine

Abstract

The utility model discloses a liquid adding device for an immunohistochemical dyeing machine. The liquid adding device comprises a cleaning head module, a Y-direction movement module, a Z-direction movement module and a liquid adding installation module, the cleaning head module mainly comprises a bottom plate, a reagent needle and a Z-direction movement module, and the Z-direction movement module drives the reagent needle to move in the Z direction; in the Y-direction movement module, a Y motor drives a Y synchronous belt to conduct transmission, and a Y sliding block drives a cleaning head module to move along a Y linear guide rail. The Z-direction movement module comprises a Z motor, a Z sliding block, a lead screw connecting block and a guide rod, and the Z motor is connected with the Z sliding block through the lead screw connecting block and drives the reagent needle to do Z-direction linear movement through the Z sliding block; in the liquid adding installation module, a base and a guide rail installation supporting column are fixed to the two ends of a Y linear guide rail through a first guide rail support and a second guide rail support correspondingly, and the supporting effect is achieved. The liquid adding device provided by the utility model is simple in structure, high in moving speed and high in liquid adding speed.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid adding devices, in particular to a liquid adding device used for an immunohistochemical staining machine. Background Art

[0002] During the sample testing process, different liquids (for example: dewaxing solution, alcohol, high pH repair solution, low pH repair solution, pure water, TBS buffer) need to be added to the specimens on the specimen rack to achieve the effect of adding liquid or flushing. Usually, the reagent needle is connected to the quantitative pump (for pumping liquid) and the rotary valve (for switching different liquids) to extract the liquid from the large-capacity reagent barrel, and then drip it on different specimens through the cleaning head (the cleaning head is equipped with a reagent needle). In order to be able to efficiently and accurately add liquid or flush each specimen on the specimen rack, the cleaning head needs to have a flexible position adjustment function so that the cleaning head can move flexibly in the horizontal and vertical directions, so that the reagent needle can reach the designated liquid adding position quickly and accurately. Utility Model Content

[0003] In view of the deficiencies in the prior art, the purpose of the utility model is to provide a liquid adding device for an immunohistochemical staining machine, which adopts a guide rail guidance + synchronous belt transmission method to realize the linear motion of the cleaning head along the Y direction; and adopts a guide rod guidance + screw transmission method to drive the reagent needle of the cleaning head to make linear motion in the Z direction. It has a simple structure, fast moving speed and fast liquid adding speed.

[0004] The technical solution adopted by the utility model to solve the technical problem is: a liquid adding device for an immunohistochemical staining machine, the liquid adding device mainly comprises:

[0005] A cleaning head module, the cleaning head module mainly comprises a bottom plate, and a reagent needle and a Z-direction motion module arranged on the bottom plate, the reagent needle is used to drip liquid, and the Z-direction motion module is used to drive the reagent needle to move along the Z direction;

[0006] A Y-direction motion module, the Y-direction motion module mainly includes a Y motor, a Y linear guide, a Y synchronous belt and a Y slider, the Y slider is connected to the cleaning head module, the Y motor drives the Y synchronous belt to drive, and the Y slider drives the cleaning head module to move along the Y linear guide;

[0007] A Z-direction motion module, which is disposed on the bottom plate. The Z-direction motion module mainly comprises a Z motor, a Z slider, a screw connecting block and a guide rod installed on the bottom plate. The guide rod is installed in a guide rod mounting hole on the Z slider. The Z motor is connected to the Z slider through the screw connecting block, and the reagent needle is driven to perform Z-direction linear motion through the Z slider;

[0008] A liquid adding installation module, which mainly includes a base, a guide rail installation support, a drag chain, a first guide rail bracket and a second guide rail bracket. The base and the guide rail installation support are respectively fixed to the two ends of the Y linear guide through the first guide rail bracket and the second guide rail bracket. The drag chain is installed at one end of the base, and the Y motor is installed on the base.

[0009] Furthermore, the cleaning head module also includes a PCB adapter board, a Z zero position optical coupler, a Z zero position plate and a Y zero position plate; the PCB adapter board is installed on the base plate through a mounting plate, the Z zero position optical coupler is installed on the base plate through a Z optical coupler mounting plate, the Z zero position plate is installed on the Z slider and cooperates with the Z zero position optical coupler, and the Y zero position plate is installed on the base plate and cooperates with the Y-axis motion module.

[0010] Furthermore, the cleaning head module also includes a reagent needle fixing block, and the reagent needle is connected to the Z slider through the reagent needle fixing block; a pipe joint is provided at the upper end of the reagent needle, and the pipe joint is used to fix the reagent needle, and the reagent needle is connected to the liquid adding assembly.

[0011] Furthermore, the cleaning head module also includes a shield and a connecting block, wherein the shield is used to protect the reagent needle and the Z-direction motion module; the connecting block is fixed to the base plate, and the connecting block is used to limit the linear motion of the cleaning head module on the Y linear guide rail.

[0012] Furthermore, the Y-axis motion module also includes a Y driving wheel and a Y driven wheel connected to both ends of the Y synchronous belt, the Y driving wheel is connected to the Y motor; the Y driven wheel is installed on the second guide rail bracket.

[0013] Furthermore, the Y-axis motion module also includes a Y zero-position optical coupler, and the Y zero-position optical coupler is fixed to one end of the Y linear guide rail through a Y optical coupler mounting plate.

[0014] Furthermore, the Y-axis motion module also includes a limit block, and there are two limit blocks, which are respectively arranged on the first guide rail bracket and the second guide rail bracket.

[0015] Furthermore, in the Z-axis motion module, a bushing is provided between the guide rod and the guide rod mounting hole; the middle portion of the guide rod is mounted on the base plate through a guide rod pressure plate, and a guide groove for accommodating the guide rod is provided between the guide rod pressure plate and the base plate.

[0016] Furthermore, the liquid adding device also includes a needle washing pool, which is fixed on the base and is used for filling the system liquid and cleaning the reagent needle.

[0017] The beneficial effects of the utility model are as follows: compared with the prior art, the liquid adding device provided by the utility model adopts a guide rail guidance + synchronous belt transmission mode, the base and the guide rail mounting pillars play a supporting role at both ends of the Y linear guide rail, the Y motor is installed on the base, drives the Y synchronous belt to move, thereby driving the cleaning head module to make a linear motion along the Y direction; adopts a guide rod guidance + screw transmission mode, the Z motor is installed on the bottom plate, and is connected to the Z slider through a screw connecting block, thereby driving the reagent needle in the cleaning head module to make a linear motion in the Z direction; the liquid adding device provided by the utility model has the advantages of simple structure, fast moving speed, fast liquid adding speed, etc. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 The present invention is a schematic diagram of the three-dimensional structure of the liquid adding device provided by the utility model.

[0019] Figure 2 This is a schematic diagram of the disassembled structure of the liquid adding device provided by the utility model.

[0020] Figure 3 This is a schematic diagram of the three-dimensional structure of the cleaning head module in the liquid adding device provided by the utility model.

[0021] Figure 4 This is a schematic diagram of the three-dimensional structure of the cleaning head module in the liquid adding device provided by the utility model.

[0022] Figure 5 This is a schematic diagram of the disassembled structure of the cleaning head module in the liquid adding device provided by the utility model.

[0023] Among them, 1-cleaning head module; 2-reagent needle; 3-needle washing pool; 4-base; 5-Y motor; 6-drag chain; 7-Y linear guide; 8-limit block; 9-Y driven wheel; 10-guide rail mounting pillar; 11-second guide rail bracket; 12-Y synchronous belt; 13-Y slider; 14-first guide rail bracket; 16-Y optical coupling mounting plate; 17-Y zero position optical coupling; 18-Y driving wheel; 19-reagent needle fixing block; 20-pipe connector; 21-Z slider; 22-Y zero position piece; 23-bushing; 24-Z optical coupling mounting plate; 25-Z zero position optical coupling; 26-PCB adapter plate; 27-bottom plate; 28-connecting block; 29-Z motor; 30-guide rod pressure plate; 31-guide rod; 32-screw rod connecting block; 33-Z zero position piece; 34-guide rod mounting hole; 35-guide groove; 36-mounting plate. DETAILED DESCRIPTION

[0024] In order to facilitate the understanding of the present invention, the present invention will be described more comprehensively with reference to the relevant drawings. The drawings provide preferred embodiments of the present invention. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to provide a more thorough and comprehensive understanding of the contents disclosed in the present invention.

[0025] Example 1

[0026] A liquid adding device for an immunohistochemical staining machine, the liquid adding device mainly comprising: a cleaning head module 1, the cleaning head module 1 mainly comprising a bottom plate 27, and a reagent needle 2 and a Z-direction motion module arranged on the bottom plate 27, the reagent needle 2 is used to drip liquid, and the Z-direction motion module is used to drive the reagent needle 2 to move along the Z direction; a Y-direction motion module, the Y-direction motion module mainly comprising a Y motor 5, a Y linear guide 7, a Y synchronous belt 12 and a Y slider 13, the Y slider 13 is connected to the cleaning head module 1, the Y motor 5 drives the Y synchronous belt 12 to transmit, and drives the cleaning head module 1 to move along the Y linear guide 7 through the Y slider 13; a Z-direction motion module, the Z-direction motion module is arranged on the bottom plate 27, and the Z-direction motion module mainly It includes a Z motor 29, a Z slider 21, a screw connecting block 32 and a guide rod 31 installed on the base plate 27, the guide rod 31 is installed in the guide rod mounting hole 34 on the Z slider 21, the Z motor 29 is connected to the Z slider 21 through the screw connecting block 32, and the reagent needle 2 is driven to make a linear motion in the Z direction through the Z slider 21; a liquid adding installation module, the liquid adding installation module mainly includes a base 4, a guide rail mounting support 10, a drag chain 6, a first guide rail bracket 14 and a second guide rail bracket 11, the base 4 and the guide rail mounting support 10 are respectively fixed to the two ends of the Y linear guide 7 through the first guide rail bracket 14 and the second guide rail bracket 11, the drag chain 6 is installed at one end of the base 4, and the Y motor 5 is installed on the base 4.

[0027] The working mode of the liquid adding device in this embodiment is as follows: the Y linear guide rail 7 is supported and fixed by the base 4 and the guide rail mounting pillars 10 at both ends, and the Y linear guide rail 7 plays a supporting and guiding role; the cleaning head module 1 is fixed on the Y slider 13, and under the drive of the Y motor 5, it moves linearly along the Y linear guide rail 7. The cleaning head module 1 is provided with a Z-direction motion module, so that the cleaning head module 1 has degrees of freedom in the Y and Z directions. The Z-direction motion module adopts a screw motor transmission mode, and drives the reagent needle 2 to move linearly in the Z direction through the Z slider 21 to reach the designated liquid adding position for operations such as liquid adding and flushing.

[0028] In one embodiment, the cleaning head module 1 further includes a PCB adapter plate 26, a Z zero position optical coupler 25, a Z zero position piece 33 and a Y zero position piece 22; the PCB adapter plate 26 is mounted on the bottom plate 27 through a mounting plate 36, the Z zero position optical coupler 25 is mounted on the bottom plate 27 through a Z optical coupler mounting plate 24, the Z zero position piece 33 is mounted on the Z slider 21 and cooperates with the Z zero position optical coupler 25, and the Y zero position piece 22 is mounted on the bottom plate 27 and cooperates with the Y-axis motion module. The Z zero position optical coupler 25 cooperates with the Z zero position piece 33 to facilitate the Z-axis motion module to reset and find the zero.

[0029] In one embodiment, the cleaning head module 1 further includes a reagent needle fixing block 19, through which the reagent needle 2 is connected to the Z slider 21; a pipe joint 20 is provided at the upper end of the reagent needle 2, and the pipe joint 20 is used to fix the reagent needle 2, and the reagent needle 2 is connected to a liquid adding component (including a quantitative pump, a rotary valve, a reagent barrel, etc., not shown). The reagent needle 2 is connected to the Z slider 21 through the reagent needle fixing block 19, and driven by the Z slider 21, the reagent needle 2 can move linearly along the Z direction.

[0030] In one embodiment, the cleaning head module 1 also includes a shield and a connecting block 28, wherein the shield is used to protect the reagent needle 2 and the Z-axis motion module; the connecting block 28 is fixed on the base plate 27, and the connecting block 28 is used to limit the linear motion of the cleaning head module 1 on the Y linear guide 7.

[0031] In one embodiment, the Y-direction motion module further includes a Y driving wheel 18 and a Y driven wheel 9 connected to both ends of the Y synchronous belt 12, the Y driving wheel 18 is connected to the Y motor 5; the Y driven wheel 9 is installed on the second guide rail bracket 11. The Y motor 5 drives the Y driving wheel 18, and the Y driving wheel 18 drives the Y synchronous belt 12 to drive, drive the Y driven wheel 9 to rotate, and finally drive the cleaning head module 1 to perform linear motion on the Y linear guide rail 7 through the Y slider 13.

[0032] In one embodiment, the Y-axis motion module further includes a Y zero position optical coupler 17, and the Y zero position optical coupler 17 is fixed to one end of the Y linear guide rail 7 through a Y optical coupler mounting plate 16. The Y zero position optical coupler 17 cooperates with the Y zero position piece 22 to facilitate the cleaning head module 1 to reset and find the zero in the direction of the Y linear guide rail 7.

[0033] In one embodiment, the Y-axis motion module further includes a limit block 8, and there are two limit blocks 8, which are respectively arranged on the first guide rail bracket 14 and the second guide rail bracket 11. The function of the limit block 8 is to limit the movement of the cleaning head module 1 along the Y linear guide rail 7.

[0034] In one embodiment, in the Z-axis motion module, a bushing 23 is provided between the guide rod 31 and the guide rod mounting hole 34; the middle portion of the guide rod 31 is mounted on the bottom plate 27 via a guide rod pressing plate 30, and a guide groove 35 for accommodating the guide rod 31 is provided between the guide rod pressing plate 30 and the bottom plate 27. When the guide rod 31 is installed, the middle portion of the guide rod 31 is fixed to the bottom plate 27 via the guide rod pressing plate 30, and the guide rod 31 is just accommodated in the guide groove 35.

[0035] In one embodiment, the liquid adding device further comprises a needle washing pool 3 , which is fixed on the base 4 . The needle washing pool 3 is used for filling the system liquid and cleaning the reagent needle 2 .

[0036] The above implementation modes are only used to illustrate the present invention, but not to limit the present invention. Ordinary technicians in the relevant technical field can make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, all equivalent technical solutions also belong to the scope of the present invention. The scope of patent protection of the present invention should be limited by the claims.

Claims

1. A liquid adding device for an immunohistochemical staining machine, characterized in that: The liquid adding device mainly comprises: A cleaning head module, the cleaning head module mainly comprises a bottom plate, and a reagent needle and a Z-direction motion module arranged on the bottom plate, the reagent needle is used to drip liquid, and the Z-direction motion module is used to drive the reagent needle to move along the Z direction; A Y-direction motion module, the Y-direction motion module mainly includes a Y motor, a Y linear guide, a Y synchronous belt and a Y slider, the Y slider is connected to the cleaning head module, the Y motor drives the Y synchronous belt to drive, and the Y slider drives the cleaning head module to move along the Y linear guide; A Z-direction motion module, which is disposed on the bottom plate. The Z-direction motion module mainly comprises a Z motor, a Z slider, a screw connecting block and a guide rod installed on the bottom plate. The guide rod is installed in a guide rod mounting hole on the Z slider. The Z motor is connected to the Z slider through the screw connecting block, and the reagent needle is driven to perform Z-direction linear motion through the Z slider; A liquid adding installation module, which mainly includes a base, a guide rail installation support, a drag chain, a first guide rail bracket and a second guide rail bracket. The base and the guide rail installation support are respectively fixed to the two ends of the Y linear guide through the first guide rail bracket and the second guide rail bracket. The drag chain is installed at one end of the base, and the Y motor is installed on the base.

2. A liquid adding device for an immunohistochemical staining machine as claimed in claim 1, characterized in that: The cleaning head module also includes a PCB adapter plate, a Z zero position optical coupler, a Z zero position plate and a Y zero position plate; the PCB adapter plate is installed on the base plate through a mounting plate, the Z zero position optical coupler is installed on the base plate through a Z optical coupler mounting plate, the Z zero position plate is installed on the Z slider and cooperates with the Z zero position optical coupler, and the Y zero position plate is installed on the base plate and cooperates with the Y-axis motion module.

3. A liquid adding device for an immunohistochemical staining machine as claimed in claim 1, characterized in that: The cleaning head module also includes a reagent needle fixing block, and the reagent needle is connected to the Z slider through the reagent needle fixing block; a pipeline connector is provided at the upper end of the reagent needle, and the pipeline connector is used to fix the reagent needle, and the reagent needle is connected to the liquid adding component.

4. A liquid adding device for an immunohistochemical staining machine as claimed in claim 1, characterized in that: The cleaning head module also includes a shield and a connecting block, wherein the shield is used to protect the reagent needle and the Z-direction motion module; the connecting block is fixed to the base plate, and the connecting block is used to limit the linear motion of the cleaning head module on the Y linear guide rail.

5. A liquid adding device for an immunohistochemical staining machine as claimed in claim 1, characterized in that: The Y-direction motion module further comprises a Y driving wheel and a Y driven wheel connected to both ends of the Y synchronous belt, wherein the Y driving wheel is connected to the Y motor; and the Y driven wheel is mounted on the second guide rail bracket.

6. A liquid adding device for an immunohistochemical staining machine as claimed in claim 1, characterized in that: The Y-axis motion module also includes a Y zero-position optical coupler, and the Y zero-position optical coupler is fixed to one end of the Y linear guide rail through a Y optical coupler mounting plate.

7. A liquid adding device for an immunohistochemical staining machine as claimed in claim 1, characterized in that: The Y-axis motion module further includes a limit block, and there are two limit blocks, which are respectively arranged on the first guide rail bracket and the second guide rail bracket.

8. A liquid adding device for an immunohistochemical staining machine as claimed in claim 1, characterized in that: In the Z-axis motion module, a bushing is provided between the guide rod and the guide rod mounting hole; the middle portion of the guide rod is mounted on the base plate via a guide rod pressure plate, and a guide groove for accommodating the guide rod is provided between the guide rod pressure plate and the base plate.

9. A liquid adding device for an immunohistochemical staining machine as claimed in claim 1, characterized in that: The liquid adding device also includes a needle washing pool, which is fixed on the base and is used for filling the system liquid and cleaning the reagent needle.

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