Communicated detection column
The connected detection column allows simultaneous detection of multiple pathogens by connecting columns with pipes, improving efficiency and accuracy by preventing reagent layer interference.
Patent Information
- Application Number
- CN202420801711.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-17
- Publication Date
- 2024-12-31
- Estimated Expiration
- 2034-04-17
AI Technical Summary
Existing methods for detecting multiple pathogens in blood samples are inefficient and prone to accuracy issues due to interference between detection layers.
A connected detection column with multiple side-by-side columns connected by a pipe, each containing a reagent layer for different pathogens, allowing simultaneous detection without interference.
Enhances detection efficiency and accuracy by enabling simultaneous detection of multiple pathogens without cross-layer interference.
Smart Images

Figure CN222280651U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical detection equipment, in particular to a connected detection column. Background Art
[0002] At present, in order to detect pathogens contained in blood samples, the principle of antibody-antigen specific binding is usually used to detect samples through test columns. However, it is usually necessary to test samples for multiple pathogens, and multiple test columns are required to load samples one by one to detect different pathogens. However, the detection efficiency is low and the use is inconvenient. In addition, a test column with multiple detection layers can be used to detect different pathogens at a time, but there may be interference between different detection layers, affecting the accuracy of the detection. Utility Model Content
[0003] The purpose of the utility model is to provide a connected detection column to solve the problems existing in the above-mentioned prior art, facilitate the detection of multiple pathogens in samples, improve the detection efficiency, and ensure the detection accuracy.
[0004] To achieve the above purpose, the utility model provides the following solutions:
[0005] The utility model provides a connected detection column, comprising a plurality of columns arranged side by side, at least one end of the column being a sample adding end, and a reagent layer being arranged in the other end of each column; a connecting pipe is arranged between two adjacent columns, and the two ends of the connecting pipe are respectively connected to connecting ports arranged on the column.
[0006] Preferably, the communication openings on adjacent columns are opposite to each other and are at the same height; and the communication pipe is configured as a straight pipe.
[0007] Preferably, the reagent layer includes a detection layer and a control layer in sequence along a direction away from the sample application end, and a partition is provided between the detection layer and the control layer.
[0008] Preferably, the partition is provided with a through hole through which the sample can pass.
[0009] Preferably, the separators are provided at both ends of the reagent layer.
[0010] Preferably, the height of the communication port is higher than the height of the reagent layer.
[0011] Preferably, the column is made of transparent material.
[0012] Preferably, a reinforcing tube is further provided between adjacent columns.
[0013] Preferably, one end of each column facing away from the reagent layer is the sample addition end.
[0014] Compared with the prior art, the utility model has achieved the following technical effects:
[0015] The utility model provides a connected detection column, which is provided with a plurality of columns arranged side by side, wherein the plurality of columns are connected by a connecting tube. When a sample needs to be tested for different pathogens, the sample is added through a sample adding end, and the sample can enter each column through the connecting port and the connecting tube to react with each reagent layer. The reagent layers in different columns can be used to detect different pathogens. In this way, different pathogens can be detected at one time, and different reagent layers do not affect each other, thereby improving the detection efficiency and ensuring the detection accuracy. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0017] Figure 1 This is a schematic diagram of the structure of the connected detection column provided in Example 1.
[0018] In the figure: 100 - interconnected detection column; 10 - column body; 11 - sample addition end; 12 - connecting port; 20 - reagent layer; 21 - detection layer; 22 - control layer; 23 - partition; 30 - connecting tube; 40 - reinforcement tube. DETAILED DESCRIPTION
[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0020] The purpose of the utility model is to provide a connected detection column to solve the problems existing in the above-mentioned prior art, facilitate the detection of multiple pathogens in samples, improve the detection efficiency, and ensure the detection accuracy.
[0021] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.
[0022] Embodiment 1
[0023] This embodiment provides a connected detection column 100, see Figure 1, including a plurality of columns 10 arranged side by side, one end of at least one column 10 being a sample addition end 11, and a reagent layer 20 being arranged in the other end of each column 10; a connecting tube 30 is arranged between two adjacent columns 10, and both ends of the connecting tube 30 are respectively connected to a connecting port 12 arranged on the column 10.
[0024] A plurality of columns 10 are arranged side by side, wherein the plurality of columns 10 are connected by a connecting tube 30. When it is necessary to detect different pathogens on a sample, the sample is added through a sample adding end 11, and the sample can enter each column 10 through the connecting port 12 and the connecting tube 30 to react with each reagent layer 20. The reagent layers 20 in different columns 10 can be used to detect different pathogens. In this way, different pathogens can be detected by adding the sample once, and different reagent layers 20 do not affect each other, thereby improving the detection efficiency and ensuring the detection accuracy.
[0025] Specifically, the number of columns 10 can be determined according to actual needs, such as being set to two, three, etc.
[0026] In the optional solution provided in this embodiment, it is more preferred that the connecting ports 12 on adjacent columns 10 are opposite and at the same height; the connecting tube 30 is configured as a straight tube. Such a configuration can ensure that the sample liquid level in each column 10 is consistent, thereby achieving uniform detection of the sample.
[0027] In the optional scheme provided in this embodiment, it is more preferred that the reagent layer 20 includes a detection layer 21 and a control layer 22 in sequence along the direction away from the sample application end 11, and a partition 23 is arranged between the detection layer 21 and the control layer 22. By setting the control layer 22 and the detection layer 21, the detection layer 21 first contacts and reacts with the sample, and by comparing with the control layer 22, the degree of reaction between the detection layer 21 and the sample pathogen can be judged for judgment; the partition 23 is arranged to facilitate demarcation for comparison; specifically, the detection layer 21 and the control layer 22 can use conventional gel detection reagents, which lose color after reacting with pathogens, so that the pathogen status is judged by the degree of discoloration of the detection layer 21.
[0028] In the optional solution provided in this embodiment, it is more preferred that the partition 23 is provided with a through hole that allows the sample to pass through; when there are a lot of samples, they can enter the control layer 22 through the through holes on the partition 23 to continue the reaction.
[0029] In the optional solution provided in this embodiment, preferably, partitions 23 are provided at both ends of the reagent layer 20 , and the position and shape of the reagent layer 20 can be positioned and fixed by the partitions 23 , and the sample enters the reagent layer 20 through the through holes on the partitions 23 .
[0030] In the optional solution provided in this embodiment, it is more preferred that the height of the communication port 12 is higher than the height of the reagent layer 20 , so that the sample can enter from above the reagent layer 20 .
[0031] In the optional solution provided in this embodiment, it is more preferred that the column 10 is set to be made of a transparent material, specifically plastic or glass, to facilitate observation of the reagent layer 20.
[0032] In the optional solution provided in this embodiment, it is more preferred that a reinforcing tube 40 is further provided between adjacent columns 10 to improve the overall strength.
[0033] In the optional scheme provided in this embodiment, it is more preferred that the end of each column 10 facing away from the reagent layer 20 is a sample loading end 11, and the sample can be loaded through any sample loading end 11. At the same time, when the sample liquid level submerges the connecting port 12, the sample flow in multiple columns 10 can still be satisfied.
[0034] The utility model uses specific examples to illustrate the principle and implementation of the utility model. The above examples are only used to help understand the method and core idea of the utility model. At the same time, for those skilled in the art, according to the idea of the utility model, there will be changes in the specific implementation and application scope. In summary, the content of this specification should not be understood as limiting the utility model.
Claims
1. A connected detection column, characterized in that: The invention comprises a plurality of columns (10) arranged side by side, wherein one end of at least one of the columns (10) is a sample addition end (11), and a reagent layer (20) is arranged in the other end of each of the columns (10); a connecting tube (30) is arranged between two adjacent columns (10), and both ends of the connecting tube (30) are respectively connected to a connecting port (12) arranged on the column (10).
2. The connected detection column according to claim 1, characterized in that: The communication openings (12) on adjacent columns (10) are opposite to each other and are located at the same height; and the communication pipe (30) is configured as a straight pipe.
3. The connected detection column according to claim 1, characterized in that: The reagent layer (20) comprises a detection layer (21) and a control layer (22) in sequence along a direction away from the sample application end (11), and a partition (23) is arranged between the detection layer (21) and the control layer (22).
4. The connected detection column according to claim 3, characterized in that: The partition (23) is provided with a through hole through which the sample can pass.
5. The connected detection column according to claim 4, characterized in that: The separators (23) are arranged at both ends of the reagent layer (20).
6. The connected detection column according to claim 2, characterized in that: The height of the communication port (12) is higher than the height of the reagent layer (20).
7. The connected detection column according to claim 1, characterized in that: The column (10) is made of a transparent material.
8. The connected detection column according to claim 1, characterized in that: A reinforcement tube (40) is also provided between adjacent columns (10).
9. The connected detection column according to claim 1, characterized in that: One end of each column (10) facing away from the reagent layer (20) is the sample addition end (11).